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high intensity exercise and telomere length

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https://www.readbyqxmd.com/read/27747783/genomic-integrity-is-favourably-affected-by-high-intensity-interval-training-in-an-animal-model-of-early-stage-chronic-kidney-disease
#1
Patrick S Tucker, Aaron T Scanlan, Rebecca K Vella, Vincent J Dalbo
BACKGROUND: Chronic kidney disease (CKD) is an irreversible disease that diminishes length and quality of life. Emerging evidence suggests CKD progression and genomic integrity are inversely and causally related. To reduce health complications related to CKD progression, chronic aerobic exercise is often recommended. To date, appraisals of differing modes of exercise, along with postulations regarding the mechanisms responsible for observed effects, are lacking. In order to examine the ability of aerobic exercise to encourage improvements in genomic integrity, we evaluated the effects of 8 weeks of high-intensity interval training (HIIT; 85 % VO2max), low intensity training (LIT; 45-50 % VO2max), and sedentary behaviour (SED), in an animal model of early-stage CKD...
December 2016: Sports Medicine—Open
https://www.readbyqxmd.com/read/22302075/physical-activity-sedentary-behavior-and-leukocyte-telomere-length-in-women
#2
Mengmeng Du, Jennifer Prescott, Peter Kraft, Jiali Han, Edward Giovannucci, Susan E Hankinson, Immaculata De Vivo
Leukocyte telomere length (LTL) is a potential indicator of cellular aging; however, its relation to physical activity and sedentary behavior is unclear. The authors examined cross-sectionally associations among activity, sedentary behavior, and LTL among 7,813 women aged 43-70 years in the Nurses' Health Study. Participants self-reported activity by questionnaire in 1988 and 1992 and sedentary behavior in 1992. Telomere length in peripheral blood leukocytes, collected in 1989-1990, was measured by quantitative polymerase chain reaction...
March 1, 2012: American Journal of Epidemiology
https://www.readbyqxmd.com/read/18295822/exercise-training-improves-the-antioxidant-enzyme-activity-with-no-changes-of-telomere-length
#3
Yun-A Shin, Jun-Hyoup Lee, Wook Song, Tae-Won Jun
The purpose of this study was to determine the changes of both oxidant and antioxidant levels with exercise training in obese middle-aged women. The association between telomere length and oxidative stress with exercise was also examined. Sixteen obese middle-aged women participated in this study. The subjects were randomly divided into exercise group (EX) and control group (CON). EX performed aerobic exercise training for 6 months. DNA was extracted from leukocytes in peripheral blood and their telomere lengths were measured by real time PCR analysis...
May 2008: Mechanisms of Ageing and Development
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