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Adnexal tumor

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https://www.readbyqxmd.com/read/29037024/treatment-outcome-and-risk-analysis-for-cataract-after-radiotherapy-of-localized-ocular-adnexal-mucosa-associated-lymphoid-tissue-malt-lymphoma
#1
Hee Hyun Park, Sea-Won Lee, Soo Yoon Sung, Byung Ock Choi
PURPOSE: We retrospectively reviewed the results of radiotherapy for localized ocular adnexal MALT lymphoma (OAML) to investigate the risk factors of cataract. METHODS: Sixty-seven patients with stage IE OAML treated with radiotherapy at Seoul St. Mary's Hospital from 2001 to 2016 were included. Median treatment dose was 30 Gy. Lens protection was done in 52 (76%) patients. Radiation therapy (RT) extent was as follows: superficial (82.1%), tumor mass (4.5%), and entire orbital socket (13...
September 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/28984773/ovarian-torsion-of-mixed-epithelial-tumor-misdiagnosed-as-a-malignancy-in-postmenopausal-woman-a-case-report
#2
Hyeji Jeon, Aeli Ryu, Hui-Gyeong Seo, Si-Hyong Jang
RATIONALE: Adnexal torsion is 1 of the most common emergency gynecological disease. It is more often diagnosed in reproductive age, but rarely in postmenopausal women. The clinical symptoms of adnexal torsion are nonspecific in postmenopausal women. Epithelial ovarian tumors are common in adults, and the risk of malignancy increases with age, especially after menopause. So, it is difficult to diagnose adnexal torsion precisely compared with reproductive women, and most cases of adnexal torsion with postmenopausal women are diagnosed as a malignancy preoperatively...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28984693/myoepithelial-rich-and-infiltrative-giant-vascular-eccrine-spiradenoma-a-unique-presentation-of-a-rare-adnexal-tumor
#3
Corey Georgesen, Cynthia Magro
A rare variant of the eccrine spiradenoma, the giant vascular eccrine spiradenoma, has been characterized as a large circumscribed and sometimes hemorrhagic solitary tumor occurring in adults older than 50 years. Histopathologically, the lesion is comprised of distinct cell populations and cystic hemorrhagic glandular spaces. We present a 68-year-old Bengali man with a giant vascular eccrine spiradenoma and describe immunohistochemical features of this tumor. In addition, we highlight unique aspects of this case, including a rich myoepithelial component and focal pseudocapsular infiltration...
September 26, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28979031/perianal-eccrine-syringofibroadenoma
#4
Atul Madhusudan Dongre, Vivek Vilas Nikam, Hari Shivaram Pathave, Nitya Malladi
Eccrine syringofibroadenoma (ESFA) is a rare eccrine ductal adnexal tumor. It shows variable presentations as solitary or multiple nodular lesions arranged in different patterns. It is most commonly seen in middle-aged to elderly patients, and most common sites include the extremities. Classic histopathological findings show anastomosing cords and strands of uniform cuboidal cells surrounded by fibrovascular stroma. Herein, we report a case of reactive ESFA which developed on the perianal region of a 31-year-old man...
September 2017: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/28960399/role-of-intracystic-cytokines-and-nitric-oxide-in-ovarian-neoplasms
#5
Agrimaldo Martins Filho, Millena Prata Jammal, Douglas Côbo Micheli, Beatriz Martins Tavares-Murta, Renata Margarida Etchebehere, Eddie Fernando Candido Murta, Rosekeila Simões Nomelini
The development of new biomarkers for the diagnosis and prognosis of ovarian cancer may provide an opportunity for new therapies. In this study, we aimed to compare cytokines (interleukin [IL]-2, IL-5, IL-6, IL-8, IL-10, and tumor necrosis factor [TNF]-α) and nitric oxide (NO) metabolite levels in non-neoplastic tumors, benign primary ovarian tumors, and malignant primary ovarian neoplasms. The secondary aim was to relate cytokine and intracystic NO metabolite levels to clinical, laboratory, and pathologic characteristics for patients with primary ovarian malignancies...
September 28, 2017: Scandinavian Journal of Immunology
https://www.readbyqxmd.com/read/28954110/concomitant-poroma-and-porocarcinoma
#6
Álvaro Abarzúa, Sergio Álvarez-Véliz, Catherina Moll-Manzur
Eccrine poromas and porocarcinomas are adnexal tumors derived from the sweat duct epithelium. However, eccrine poroma is benign in nature, whilst eccrine porocarcinoma is regarded as its malignant counterpart. We report the case of a man who presented simultaneously with an eccrine poroma and eccrine porocarcinoma. Both lesions had no clear distinctive features, enhancing the need of high-level clinical suspicion together with surgical excision and histopathology for prompt diagnosis confirmation.
July 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28953010/the-rcpa-quality-assurance-program-in-dermatopathology-a-retrospective-review
#7
Martyn Peck, Trevor W Beer, Tony Badrick, Benjamin A Wood
AIMS: To review the Royal College of Pathologists of Australasia (RCPA) Quality Assurance Program Dermatopathology module from 2005 to 2016 to assess diagnostic performance, changes over time, and areas of diagnostic difficulty. METHODS: The computerized records of the RCPA Dermatopathology subspecialist module were reviewed. Cases were categorized into groups including nonneoplastic disorders, neoplasms, and cases with multiple diagnoses. The performance of participants over time in each of these categories and in more specific areas (including melanocytic and adnexal neoplasms) was assessed...
September 20, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28945214/clear-cell-carcinoma-of-the-endometrium-evaluation-of-prognostic-parameters-in-a-multi-institutional-cohort-of-165-cases
#8
Eman Abdulfatah, Sharif Sakr, Sumi Thomas, Zaid Al-Wahab, David G Mutch, Sean Dowdy, Sudeshna Bandyopadhyay, Adnan Munkarah, Mohamed Elshaikh, Robert Morris, Rouba Ali-Fehmi
OBJECTIVES: Clear cell carcinoma (CCC) comprises a rare yet an aggressive subtype, accounting for less than 5% of all uterine carcinomas. Several clinicopathologic features have been predictive of poor prognosis; however, data remain controversial. The aim of this study was to evaluate the clinicopathologic features of a multi-institutional cohort of endometrial CCC in order to identify which, if any, have prognostic significance. METHODS: Retrospective review of endometrial CCC diagnosed between 1995 and 2012 at 3 institutions was conducted to evaluate clinicopathologic parameters: age, race, tumor size, stage, myometrial invasion (MI), lymphovascular invasion, lymph node and adnexal involvement, adjuvant therapy, and outcomes...
October 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28939925/ocular-adnexal-marginal-zone-lymphoma-of-mucosa-associated-lymphoid-tissue
#9
REVIEW
Dimitrios Kalogeropoulos, Alexandra Papoudou-Bai, Panagiotis Kanavaros, Chris Kalogeropoulos
Ocular adnexal lymphomas are a group of heterogeneous neoplasms representing approximately 1-2% of non-Hodgkin lymphomas and 8% of extranodal lymphomas. The incidence of primary ocular adnexal lymphoid tumors has raised over the last decades, and this could be probably attributed to the more sophisticated diagnostic techniques. Due to the wide spectrum of clinical manifestations, ocular tissue biopsy is important in order to set a precise diagnosis based on histological, immunophenotypical and, in some cases, molecular findings...
September 22, 2017: Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/28937387/malignant-chondroid-syringoma-of-thigh-with-late-metastasis-to-lung-a-very-rare-case-report
#10
Mayur Kothiya, Neha Mittal, Rajiv Kumar, Shubhada Kane
Mixed/biphasic tumors include epithelial-myoepithelial tumors, pleomorphic adenoma, matrix-producing tumors, cutaneous mixed tumors such as chondroid syringoma (CS), malignant mixed tumors (carcinosarcomas), pulmonary blastomas (in lung), and many others. Morphology may show overlap between various mixed tumors. At any particular site, whether these tumors are primary or metastasis from other sites is difficult to determine, more so if primary is unknown or not disclosed. CS is a rare benign mixed/biphasic skin adnexal tumor, considered as cutaneous counterpart of pleomorphic adenoma...
July 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28935270/preoperative-c-reactive-protein-serum-levels-as-a-predictive-diagnostic-marker-in-patients-with-adnexal-masses
#11
Elisabeth Reiser, Stefanie Aust, Veronika Seebacher, Alexander Reinthaller, Samir Helmy-Bader, Richard Schwameis, Christoph Grimm, Stephan Polterauer
OBJECTIVE: To evaluate C-reactive protein (CRP) serum levels as a preoperative predictive marker for ovarian cancer in patients with adnexal masses. METHODS: CRP serum levels of 1843 adnexal masses and subsequent surgery were investigated (patients with benign ovarian tumors: n=1423; borderline tumor of the ovary [BTO]: n=83; EOC: n=337). Test characteristics and predictive values of CRP serum levels were investigated by univariate analysis and multivariate binary logistic regression models...
September 18, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28914967/chemotherapy-response-score-is-a-useful-histological-predictor-of-prognosis-in-high-grade-serous-carcinoma
#12
Authors Priya Singh, Vikrant Kaushal, Bhavana Rai, Arvind Rajwanshi, Nalini Gupta, Pranab Dey, Rashi Garg, Manish Rohilla, Vanita Suri, Sushmita Ghoshal, Radhika Srinivasan
AIM: High grade serous carcinoma (HGSC) is the most common tubal/ovarian malignant tumor usually presenting in advance stage. Interval debulking surgery (IDS) post neoadjuvant chemotherapy (NACT) has been increasingly in use for the management of these patients. Chemotherapy response score (CRS) has been proposed for grading response of tubo-ovarian HGSC to NACT on the basis of examination of IDS specimens. Our aim was to evaluate CRS in post NACT cases, assess the interobserver agreement and correlate it to overall and progression- free survival...
September 15, 2017: Histopathology
https://www.readbyqxmd.com/read/28913138/chondrosarcoma-mimicking-an-adnexal-mass-a-very-rare-case-report
#13
Hüseyin Çağlayan Özcan, Aynur Mustafa, Zehra Bozdağ, Seyhun Sucu, Özcan Balat
Chondrosarcoma is considered as a common primary bone sarcoma. These sarcomas can form large masses without any specific symptoms because there are no barriers in pelvic anatomy to prevent the enlargement of tumors, and can mimic ovarian masses. We present a pelvic chondrosarcoma in a woman aged 37 years who was misdiagnosed as having an ovarian mass due to the limited information obtained from imaging studies. Pelvic chondrosarcoma should be considered in patients who have pelvic masses with solid components...
March 2017: Turk J Obstet Gynecol
https://www.readbyqxmd.com/read/28913135/prognostic-risk-factors-for-lymph-node-involvement-in-patients-with-endometrial-cancer
#14
Tayfun Toptaş, Tayup Şimşek, Şeyda Karaveli
OBJECTIVE: We aimed to analyze variables affecting lymph node (LN) involvement and to assess the need for systematic lymphadenectomy in patients with endometrial cancer (EC). MATERIALS AND METHODS: A single centre retrospective analysis was conducted in a total of 128 consecutive patients with EC who underwent systematic pelvic or combined pelvic and paraaortic lymphadenectomy between 2009 and 2012. Mann-Whitney U, chi-square, and Fisher's exact test were used for univariate analyses when appropriate...
March 2017: Turk J Obstet Gynecol
https://www.readbyqxmd.com/read/28881040/comprehensive-histopathologic-comparison-of-epidermotropic-dermal-metastatic-melanoma-and-primary-nodular-melanoma
#15
Stephanie L Skala, David P Arps, Lili Zhao, Kelly B Cha, Min Wang, Paul W Harms, Aleodor A Andea, Douglas R Fullen, May P Chan
AIMS: Metastatic melanoma involving the epidermis and/or upper dermis may show significant histologic overlap with primary cutaneous melanoma, especially the nodular subtype. Proper histopathologic classification is crucial to appropriate staging and management, yet often challenging. This study aims to identify helpful histopathologic features in differentiating epidermotropic/dermal metastatic melanoma (EDMM) and primary nodular melanoma (PNM). METHODS AND RESULTS: A cohort of EDMM (n=74) and PNM (n=75) was retrospectively reviewed for various histopathologic features, and the data were compared between groups by univariate analysis...
September 7, 2017: Histopathology
https://www.readbyqxmd.com/read/28860920/eyelid-trichilemmal-carcinoma
#16
Michael K Chai, Phillip Tenzel, Codrin Iacob, Adrienne Jordan, Harsha S Reddy
Trichilemmal carcinomas are rare malignant adnexal tumors which can involve the head and, rarely, the eyelid. Accurate diagnosis and differentiation from basal cell carcinoma or trichoepithelioma are dependent on histopathological and immunohistochemical analysis. We report a case of an eyelid mass, initially diagnosed by incisional biopsy as a trichoepithelioma, later found on excisional biopsy to be a trichilemmal carcinoma and present a review of the literature of the histopathology, differential diagnosis and management...
July 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/28851436/postmenopausal-mild-hirsutism-and-hyperandrogenemia-due-to-granulosa-cell-tumor-of-the-ovary-a-case-report
#17
Mulat Adefris, Elfalet Fekadu
BACKGROUND: Among classes of ovarian tumor, granulosa cell tumors are the least common. In approximately 10% of cases of granulosa cell tumor, androgen will be secreted which will present with hirsutism and hyperandrogenemia. We describe a woman with ovarian granulosa cell tumor who presented with hirsutism. CASE PRESENTATION: A 50-year-old woman of Amhara ethnicity, para III, abortion I (induced), presented with excessive hair on her face and lower abdomen of 4 years' duration which affected her quality of life...
August 30, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28845118/metastatic-adnexal-cancer-in-a-man
#18
Rashmi Advani, Manhal Izzy, Ashwin Akki, Calley Levine, Nicole Panarelli, Lawrence J Brandt
Primary cutaneous adnexal neoplasms are mostly benign in nature; however, there have been reports of malignant adnexal tumors with distant metastasis to lymph nodes. Adnexal cutaneous malignancy with metastasis to the gastrointestinal tract has never been reported. Here, we present a rare case of a man with primary adnexal cutaneous adenocarcinoma who presented with symptomatic anemia secondary to occult gastrointestinal bleeding, found to be from gastrointestinal metastasis of the adnexal malignancy.
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28841778/dermatopathology-101-part-2-skin-tumors
#19
Julia Liersch, Amelie von Köckritz, Jörg Schaller
The present CME article highlights fundamental aspects with respect to the histopathology of the most common skin tumors (epidermal, adnexal, melanocytic, and mesenchymal), their laboratory workup, as well as the importance of supplementary immunohistochemical and molecular studies. The information provided is meant to assist experienced clinicians in choosing the correct biopsy technique and in interpreting dermatopathology reports, and to provide dermatology residents with a better understanding of dermatopathology...
September 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28834973/simple-rules-not-so-simple-the-use-of-international-ovarian-tumor-analysis-iota-terminology-and-simple-rules-in-inexperienced-hands-in-a-prospective-multicenter-cohort-study
#20
Evelyne Meys, Iris Rutten, Roy Kruitwagen, Brigitte Slangen, Sandrina Lambrechts, Helen Mertens, Ernst Nolting, Dieuwke Boskamp, Toon Van Gorp
Objectives To analyze how well untrained examiners - without experience in the use of International Ovarian Tumor Analysis (IOTA) terminology or simple ultrasound-based rules (simple rules) - are able to apply IOTA terminology and simple rules and to assess the level of agreement between non-experts and an expert. Methods This prospective multicenter cohort study enrolled women with ovarian masses. Ultrasound was performed by non-expert examiners and an expert. Ultrasound features were recorded using IOTA nomenclature, and used for classifying the mass by simple rules...
August 23, 2017: Ultraschall in der Medizin
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