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the st george respiratory questionnaire

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https://www.readbyqxmd.com/read/28108209/the-impact-of-cognitive-impairment-on-efficacy-of-pulmonary-rehabilitation-in-patients-with-copd
#1
Fiona A H M Cleutjens, Martijn A Spruit, Rudolf W H M Ponds, Lowie E G W Vanfleteren, Frits M E Franssen, Jeanette B Dijkstra, Candy Gijsen, Emiel F M Wouters, Daisy J A Janssen
OBJECTIVES: To compare changes in pulmonary rehabilitation (PR) dropout and outcomes between chronic obstructive pulmonary disease (COPD) patients with and without cognitive impairment. DESIGN: A cross-sectional observational study. SETTING: Patients with COPD were recruited from a PR centre in the Netherlands. PARTICIPANTS: The study population consisted of 157 patients with clinically stable COPD who were referred for and completed PR...
January 17, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28102972/evaluating-the-clinical-copd-questionnaire-a-systematic-review
#2
REVIEW
Zijing Zhou, Aiyuan Zhou, Yiyang Zhao, Ping Chen
The Clinical COPD Questionnaire (CCQ) is recommended by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) to evaluate health status in patients with COPD. The objective of this work was to systemically assess the reliability, validity, responsiveness and minimum clinically important difference (MCID) of the CCQ. A structured search was conducted in three databases to identify articles that evaluated the psychometric properties of the CCQ in individuals with COPD. Two investigators screened the title, abstract and full text of the articles to determine study eligibility and performed the data extraction...
February 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28100551/psychometric-properties-of-the-st-george-s-respiratory-questionnaire-in-patients-with-idiopathic-pulmonary-fibrosis
#3
Jeffrey J Swigris, Dirk Esser, Hilary Wilson, Craig S Conoscenti, Hendrik Schmidt, Wibke Stansen, Nancy Kline Leidy, Kevin K Brown
The St George's Respiratory Questionnaire (SGRQ) has been used to measure health-related quality of life (HRQoL) in patients with idiopathic pulmonary fibrosis (IPF).This analysis evaluated the psychometric properties of the SGRQ using data from 428 patients with IPF who participated in a 12-month, randomised, placebo-controlled phase II trial of nintedanib.Internal consistency (Cronbach's α) was 0.91 for SGRQ total and >0.70 for domain scores. Test-retest reliability (intraclass correlation coefficients) was 0...
January 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28099192/aerobic-exercise-training-in-very-severe-chronic-obstructive-pulmonary-disease-a-systematic-review-and-meta-analysis
#4
Mara Paneroni, Carla Simonelli, Michele Vitacca, Nicolino Ambrosino
OBJECTIVE: To evaluate the effectiveness of exercise training in patients with very severe chronic obstructive pulmonary disease (COPD). DESIGN: We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Cumulative Index to Nursing and Allied Health Literature databases using the following as search terms: COPD, Chronic Obstructive Pulmonary Disease, Exercise, and Pulmonary Rehabilitation. We included randomized controlled trials (RCTs) of subjects with forced expiratory volume in the first second of less than 35% of the predicted normal value enrolled in in-patient, outpatient, or home- or community-based training programs lasting at least 4 weeks with respect to usual care...
January 17, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28096283/laba-lama-combination-in-copd-a-meta-analysis-on-the-duration-of-treatment
#5
REVIEW
Luigino Calzetta, Paola Rogliani, Josuel Ora, Ermanno Puxeddu, Mario Cazzola, Maria Gabriella Matera
When there are no randomised clinical trials directly comparing all relevant treatment options, an indirect treatment comparison via meta-analysis of the available clinical evidence is an acceptable alternative. However, meta-analyses may be very misleading if not adequately performed. Here, we propose and validate a simple and effective approach to meta-analysis for exploring the effectiveness of long-acting β2-agonist (LABA)/long-acting muscarinic antagonist (LAMA) fixed-dose combinations in chronic obstructive pulmonary disease...
January 2017: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/28095852/the-st-george-s-respiratory-questionnaire-as-a-prognostic-factor-in-ipf
#6
Taiki Furukawa, Hiroyuki Taniguchi, Masahiko Ando, Yasuhiro Kondoh, Kensuke Kataoka, Osamu Nishiyama, Takeshi Johkoh, Junya Fukuoka, Koji Sakamoto, Yoshinori Hasegawa
BACKGROUND: It is unclear whether health related quality of life (HRQL) may have a predictive value for mortality in idiopathic pulmonary fibrosis (IPF). We investigated the relationship between HRQL assessed using the St. George's Respiratory Questionnaire (SGRQ) and survival time in patients with IPF, and tried to determine a clinical meaningful cut off value to predict poorer survival rates. METHODS: We retrospectively analyzed consecutive patients with IPF who underwent an initial evaluation from May 2007 to December 2012...
January 17, 2017: Respiratory Research
https://www.readbyqxmd.com/read/28090299/tadalafil-therapy-for-sarcoidosis-associated-pulmonary-hypertension
#7
H J Ford, R P Baughman, R Aris, P Engel, J F Donohue
Sarcoidosis-associated pulmonary hypertension (SAPH) is estimated to occur in at least 5% or more of sarcoidosis patients, and it contributes to significant morbidity and mortality. Optimal therapy for SAPH is not well established. We performed a 24-week open-label trial of tadalafil for SAPH at 2 academic medical centers. Subjects were required to have confirmed sarcoidosis plus a right heart catheterization within 12 months of enrollment showing a mean pulmonary artery pressure ≥ 25 mmHg, a pulmonary artery wedge pressure ≤ 15 mmHg, and a calculated pulmonary vascular resistance ≥ 3 Wood units...
December 2016: Pulmonary Circulation
https://www.readbyqxmd.com/read/28079846/patient-confidence-and-quality-of-life-in-idiopathic-pulmonary-fibrosis-and-sarcoidosis
#8
Jalpa Kotecha, Christopher Atkins, Andrew Wilson
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) and sarcoidosis impact significantly on health-related quality of life (HRQOL). There are few studies on the impact of patient confidence on HRQOL in these conditions. OBJECTIVES: 1. To investigate whether patient confidence is associated with HRQOL, anxiety, depression, dyspnoea or fatigue. 2. To assess if patient confidence is associated with inpatient admissions, access to community healthcare and, for IPF patients, mortality and disease severity...
December 23, 2016: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
https://www.readbyqxmd.com/read/28060921/does-an-integrated-care-intervention-for-copd-patients-have-long-term-effects-on-quality-of-life-and-patient-activation-a-prospective-open-controlled-single-center-intervention-study
#9
Elena Titova, Øyvind Salvesen, Signe Berit Bentsen, Synnøve Sunde, Sigurd Steinshamn, Anne Hildur Henriksen
BACKGROUND: Implementation of the COPD-Home integrated disease management (IDM) intervention at discharge after hospitalizations for acute exacerbations of COPD (AECOPD) led to reduced hospital utilization during the following 24 months compared to the year prior to study start. AIMS: To analyze the impact of the COPD-Home IDM intervention on health related quality of life, symptoms of anxiety and depression, and the degree of patient activation during 24 months of follow-up and to assess the association between these outcomes...
2017: PloS One
https://www.readbyqxmd.com/read/28044005/biomechanical-ct-metrics-are-associated-with-patient-outcomes-in-copd
#10
Sandeep Bodduluri, Surya P Bhatt, Eric A Hoffman, John D Newell, Carlos H Martinez, Mark T Dransfield, Meilan K Han, Joseph M Reinhardt
BACKGROUND: Traditional metrics of lung disease such as those derived from spirometry and static single-volume CT images are used to explain respiratory morbidity in patients with COPD, but are insufficient. We hypothesised that the mean Jacobian determinant, a measure of local lung expansion and contraction with respiration, would contribute independently to clinically relevant functional outcomes. METHODS: We applied image registration techniques to paired inspiratory-expiratory CT scans and derived the Jacobian determinant of the deformation field between the two lung volumes to map local volume change with respiration...
January 2, 2017: Thorax
https://www.readbyqxmd.com/read/28019103/translation-and-validation-of-the-king-s-brief-interstitial-lung-disease-k-bild-questionnaire-in-french-italian-swedish-and-dutch
#11
Monique Wapenaar, Amit S Patel, Surinder S Birring, Ron T van Domburg, Eric Wp Bakker, Virginia Vindigni, C Magnus Sköld, Vincent Cottin, Carlo Vancheri, Marlies S Wijsenbeek
No disease-specific instruments exist in Dutch, French, Italian, and Swedish to measure health status in idiopathic pulmonary fibrosis (IPF) and other interstitial lung diseases (ILDs). The King's Brief Interstitial Lung Disease (K-BILD) is a 15-item validated questionnaire assessing health status in patients with ILD. The aim of this study was to translate and validate the K-BILD to French, Italian, Swedish, and Dutch versions. The K-BILD was translated following a forward-backward multistep procedure and tested in structured patient interviews...
January 1, 2016: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28012491/associations-between-the-distance-covered-in-the-incremental-shuttle-walk-test-and-lung-function-and-health-status-in-patients-with-chronic-obstructive-pulmonary-disease
#12
Atsuhito Ushiki, Shuhei Nozawa, Masanori Yasuo, Kazuhisa Urushihata, Hiroshi Yamamoto, Masayuki Hanaoka, Keisaku Fujimoto
BACKGROUND: Field walk tests such as the incremental shuttle walk test (ISWT) are simple tests for assessing the degree of disability in individuals with chronic obstructive pulmonary disease (COPD). In the present study, the correlations between exercise performance in the ISWT, lung function, and health status were examined in patients with COPD of varying severities. METHODS: A retrospective examination of 277 COPD patients was performed using the ISWT and lung function tests along with assessment of health status using St...
January 2017: Respiratory Investigation
https://www.readbyqxmd.com/read/28008244/indacaterol-glycopyrronium-in-symptomatic-patients-with-copd-gold-b-and-gold-d-versus-salmeterol-fluticasone-illuminate-lantern-pooled-analysis
#13
Claus Vogelmeier, Nanshan Zhong, Michael J Humphries, Karen Mezzi, Robert Fogel, Giovanni Bader, Francesco Patalano, Donald Banerji
BACKGROUND: Indacaterol/glycopyrronium (IND/GLY) is approved for maintenance treatment of adult patients with COPD. This post hoc analysis explored the efficacy and safety of IND/GLY versus salmeterol/fluticasone (SFC) in symptomatic (Global Initiative for Chronic Obstructive Lung Disease [GOLD] B and GOLD D) patients with moderate-to-severe COPD. PATIENTS AND METHODS: Data from LANTERN and ILLUMINATE studies were pooled and analyzed. In both studies, symptomatic COPD patients were randomized to once-daily IND/GLY 110 μg/50 μg or twice-daily SFC 50 μg/500 μg...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28001000/echocardiographic-abnormalities-and-their-impact-on-health-status-in-patients-with-copd-referred-for-pulmonary-rehabilitation
#14
Sarah Houben-Wilke, Martijn A Spruit, Nicole H M K Uszko-Lencer, Gosia Otkinska, Lowie E G W Vanfleteren, Paul W Jones, Emiel F M Wouters, Frits M E Franssen
BACKGROUND AND OBJECTIVE: Both patients with cardiac diseases as well as those with COPD report an impaired health status. The frequencies of objectively assessed co-morbid cardiac diseases and their impact on health status in patients with COPD are unknown. We aimed to investigate echocardiographic abnormalities and their impact on health status in a large cohort of patients with COPD referred for pulmonary rehabilitation (PR). METHODS: In this cross-sectional, observational analyses, demographic and clinical characteristics were assessed during an inpatient pre-PR assessment...
December 21, 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/27998692/squill-oxymel-a-traditional-formulation-from-drimia-maritima-l-stearn-as-an-add-on-treatment-in-patients-with-moderate-to-severe-persistent-asthma-a-pilot-triple-blind-randomized-clinical-trial
#15
Fatemeh Nejatbakhsh, Hossein Karegar-Borzi, Gholamreza Amin, Alireza Eslaminejad, Mostafa Hosseini, Mahbubeh Bozorgi, Mehrnaz Asadi Gharabaghi
ETHNOPHARMACOLOGICAL RELEVANCE: In Traditional Iranian Medicine (TIM), Squill (Drimia maritima (L.) Stearn) Oxymel was utilized in the treatment of asthma. Squill has been reported to exert anti-inflammatory, anti-oxidant, anti-cholinergic, and mucus secretion modulating effects. OBJECTIVE: This study aimed to make a preliminary evaluation of the efficacy and safety of an add-on Squill Oxymel treatment in patients with moderate to severe persistent asthma. METHODS: In a 6-week, triple-blind, randomized, placebo-controlled trial, 60 patients with stable moderate to severe persistent asthma were randomly allocated to receive either 10ml syrup of Squill Oxymel, simple oxymel, or a placebo 2 times a day, as an add-on to their routine treatment (inhaled corticosteroids and β2 agonists)...
January 20, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27997252/outcomes-of-pulmonary-rehabilitation-for-copd-in-older-patients-a-comparative-study
#16
Deirdre Bennett, Bernadette Bowen, Padriac McCarthy, Abi Subramaniam, Michael O'Connor, Mike T Henry
Pulmonary rehabilitation (PR) is established as an effective intervention in optimising function and quality of life in patients with chronic obstructive pulmonary disease (COPD). However, there are very limited data on the effectiveness of PR in older patients with COPD. We reviewed all patients attending an 8-week outpatient programme. Patients were divided into two groups; Group A (n = 202), below 70 years, and Group B (n = 122), above 70 years of age. Outcomes in both patient subgroups were compared using FEV(1), Incremental Shuttle Walk Test (ISWT), Endurance Shuttle Walk Test (ESWT), Grip Strength, St...
December 20, 2016: COPD
https://www.readbyqxmd.com/read/27997064/nintedanib-in-japanese-patients-with-idiopathic-pulmonary-fibrosis-a-subgroup-analysis-of-the-inpulsis%C3%A2-randomized-trials
#17
Arata Azuma, Hiroyuki Taniguchi, Yoshikazu Inoue, Yasuhiro Kondoh, Takashi Ogura, Sakae Homma, Tsuyoshi Fujimoto, Wataru Sakamoto, Yukihiko Sugiyama, Toshihiro Nukiwa
BACKGROUND AND OBJECTIVE: Idiopathic pulmonary fibrosis (IPF) is a specific form of chronic, progressive fibrosing interstitial pneumonia. Nintedanib significantly reduced the annual rate of decline in forced vital capacity (FVC) compared with placebo in patients with IPF in two replicate trials (INPULSIS®). We examined the efficacy and safety of nintedanib in Japanese patients. METHODS: We conducted pre-specified subgroup analyses of the annual rate of decline in FVC, time to first acute exacerbation (AE), change from baseline in St George's Respiratory Questionnaire (SGRQ) total score and safety using pooled data from the INPULSIS® trials for Japanese patients...
December 20, 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/27994447/interpreting-patient-reported-outcomes-from-clinical-trials-in-copd-a-discussion
#18
REVIEW
Paul W Jones, Stephen Rennard, Maggie Tabberer, John H Riley, Mitra Vahdati-Bolouri, Neil C Barnes
One of the challenges faced by the practising physician is the interpretation of patient-reported outcomes (PROs) in clinical trials and the relevance of such data to their patients. This is especially true when caring for patients with progressive diseases such as COPD. In an attempt to incorporate the patient perspective, many clinical trials now include assessments of PROs. These are formalized methods of capturing patient-centered information. Given the importance of PROs in evaluating the potential utility of an intervention for a patient with COPD, it is important that physicians are able to critically interpret (and critique) the results derived from them...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27990628/action-plans-with-brief-patient-education-for-exacerbations-in-chronic-obstructive-pulmonary-disease
#19
REVIEW
Maxwell Howcroft, E Haydn Walters, Richard Wood-Baker, Julia Ae Walters
BACKGROUND: Exacerbations of chronic obstructive pulmonary disease (COPD) are a major driver of decline in health status and impose high costs on healthcare systems. Action plans offer a form of self-management that can be delivered in the outpatient setting to help individuals recognise and initiate early treatment for exacerbations, thereby reducing their impact. OBJECTIVES: To compare effects of an action plan for COPD exacerbations provided with a single short patient education component and without a comprehensive self-management programme versus usual care...
19, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27932876/effectiveness-of-neuromuscular-electrical-stimulation-for-the-rehabilitation-of-moderate-to-severe-copd-a-meta-analysis
#20
Rong-Chang Chen, Xiao-Ying Li, Li-Li Guan, Bing-Peng Guo, Wei-Liang Wu, Zi-Qing Zhou, Ya-Ting Huo, Xin Chen, Lu-Qian Zhou
PURPOSE: Patients with COPD often experience skeletal muscle dysfunction. For those who are unable or unwilling to undertake physical training, neuromuscular electrical stimulation (NMES) may provide an alternative method of rehabilitation. The purpose of this meta-analysis was to investigate the controversial topic of whether this therapy is effective in patients with moderate-to-severe COPD. PATIENTS AND METHODS: We pooled data from nine trials published between January 9, 2002 and January 4, 2016 across PubMed, Embase, Cochrane Central Register of Controlled Trials, Google Scholar, and relevant websites for randomized controlled trials...
2016: International Journal of Chronic Obstructive Pulmonary Disease
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