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https://www.readbyqxmd.com/read/27932876/effectiveness-of-neuromuscular-electrical-stimulation-for-the-rehabilitation-of-moderate-to-severe-copd-a-meta-analysis
#1
Rong-Chang Chen, Xiao-Ying Li, Li-Li Guan, Bing-Peng Guo, Wei-Liang Wu, Zi-Qing Zhou, Ya-Ting Huo, Xin Chen, Lu-Qian Zhou
PURPOSE: Patients with COPD often experience skeletal muscle dysfunction. For those who are unable or unwilling to undertake physical training, neuromuscular electrical stimulation (NMES) may provide an alternative method of rehabilitation. The purpose of this meta-analysis was to investigate the controversial topic of whether this therapy is effective in patients with moderate-to-severe COPD. PATIENTS AND METHODS: We pooled data from nine trials published between January 9, 2002 and January 4, 2016 across PubMed, Embase, Cochrane Central Register of Controlled Trials, Google Scholar, and relevant websites for randomized controlled trials...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27930803/pulmonary-rehabilitation-following-exacerbations-of-chronic-obstructive-pulmonary-disease
#2
REVIEW
Milo A Puhan, Elena Gimeno-Santos, Christopher J Cates, Thierry Troosters
BACKGROUND: Guidelines have provided positive recommendations for pulmonary rehabilitation after exacerbations of chronic obstructive pulmonary disease (COPD), but recent studies indicate that postexacerbation rehabilitation may not always be effective in patients with unstable COPD. OBJECTIVES: To assess effects of pulmonary rehabilitation after COPD exacerbations on hospital admissions (primary outcome) and other patient-important outcomes (mortality, health-related quality of life (HRQL) and exercise capacity)...
December 8, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27923938/computerized-respiratory-sounds-novel-outcomes-for-pulmonary-rehabilitation-in-copd
#3
Cristina Jácome, Alda Marques
BACKGROUND: Computerized respiratory sounds are a simple and noninvasive measure to assess lung function. Nevertheless, their potential to detect changes after pulmonary rehabilitation (PR) is unknown and needs clarification if respiratory acoustics are to be used in clinical practice. Thus, this study investigated the short- and mid-term effects of PR on computerized respiratory sounds in subjects with COPD. METHODS: Forty-one subjects with COPD completed a 12-week PR program and a 3-month follow-up...
December 6, 2016: Respiratory Care
https://www.readbyqxmd.com/read/27923937/low-volume-whole-body-vibration-training-improves-exercise-capacity-in-subjects-with-mild-to-severe-copd
#4
Marc Spielmanns, Tobias Boeselt, Rainer Gloeckl, Anja Klutsch, Henrike Fischer, Henryk Polanski, Christoph Nell, Jan H Storre, Wolfram Windisch, Andreas R Koczulla
BACKGROUND: The objective of this study was to investigate the benefits of a low-volume out-patient whole-body vibration training (WBVT) program on exercise capacity in comparison with a calisthenics training program in subjects with COPD. METHODS: In this single-center randomized controlled trial, 29 subjects with mild to severe COPD were randomized to WBVT or to calisthenics training, including relaxation and breathing retraining in combination with calisthenics exercises...
December 6, 2016: Respiratory Care
https://www.readbyqxmd.com/read/27920518/significant-lung-volume-reduction-with-endobronchial-valves-in-a-patient-despite-the-presence-of-microcollaterals-masked-by-low-flow-chartis-phenotype
#5
Yan Yin, Gang Hou, Felix J Herth, Xiao-Bo Wang, Qiu-Yue Wang, Jian Kang
Satisfactory functional outcomes following bronchoscopic lung volume reduction (BLVR) using endobronchial valves (EBVs) depend on the absence of collateral ventilation (CV) between the target and adjunct lobes. The Chartis system has proven to be useful for determining whether CV is present or absent, but this system can also erroneously indicate the absence of CV, which can lead to BLVR failure. Here, we describe low-flow Chartis phenotype in the target lobe resulted in difficult judgment of existence of CV...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27893695/clinical-assessment-tests-in-evaluating-patients-with-chronic-obstructive-pulmonary-disease-a-cross-sectional-study
#6
Ming-Lung Chuang, I-Feng Lin, Chai-Yuan Lee
Exertional dyspnea scales (EDS) and health-related quality-of-life questionnaires (HRQoLQs) are used to assess chronic obstructive pulmonary disease (COPD). The GOLD guidelines categorize patients according to either 1 of these 2 domains, the lung function and the frequency of acute exacerbations in the preceding year, however with inconsistent results. Combining EDS and HRQoLQs may yield better results; however, the best combination is unclear. Whether the EDS quantifies the exercise capacity or the dyspnea perception is also unclear...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27890988/variability-in-proteinase-antiproteinase-balance-nutritional-status-and-quality-of-life-in-stable-chronic-obstructive-pulmonary-disease-due-to-tobacco-and-nontobacco-etiology
#7
Anant Mohan, Mini Sharma, Arvind Uniyal, Rajlaxmi Borah, Kalpana Luthra, R M Pandey, Karan Madan, Vijay Hadda, Randeep Guleria
CONTEXT: Although the role of proteinase/antiproteinase imbalance in chronic obstructive pulmonary disease (COPD) due to tobacco is well established, information in COPD due to nontobacco etiology is sparse. AIMS: To assess the variability in metalloproteinase activity in COPD related to tobacco and nontobacco causes. SETTINGS AND DESIGN: This is a hospital-based, prospective, observational study. SUBJECTS AND METHODS: Serum matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinases-1 (TIMP-1) were estimated in 200 subjects divided equally into four groups, i...
November 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27888996/the-effects-of-chronic-obstructive-pulmonary-disease-self-management-interventions-on-improvement-of-quality-of-life-in-copd-patients-a-meta-analysis
#8
REVIEW
Danielle Cannon, Nicholas Buys, Krishna Bajee Sriram, Siddharth Sharma, Norman Morris, Jing Sun
This article aimed to analyse the outcome of self-management randomised control trials and their impact upon chronic obstructive pulmonary disease patients' health outcomes using meta-analysis approach. PubMed, Scopus, CINAHL, Web of Science databases and Cochrane Library, were searched for articles between 1990 and December 2015 by two researchers. Self-management programs significantly improved patients' quality of life across all domains of the St George Respiratory Questionnaire (SGRQ) (activity -2.21 (95% CI: -3...
December 2016: Respiratory Medicine
https://www.readbyqxmd.com/read/27886854/efficacy-and-safety-of-indacaterol-glycopyrronium-in-japanese-patients-with-copd-pooled-analysis-of-shine-and-arise
#9
Kazuhisa Asai, Kazuto Hirata, Shu Hashimoto, Yoshinosuke Fukuchi, Tetsuji Kitawaki, Kimitoshi Ikeda, Robert Fogel, Donald Banerji
BACKGROUND: To better evaluate the efficacy and safety of the indacaterol/glycopyrronium (IND/GLY) fixed-dose combination versus tiotropium in Japanese patients, a pooled data analysis was conducted from the SHINE and ARISE studies, which were part of the IND/GLY clinical trial program. METHODS: Japanese patients with moderate-to-severe COPD were included in the analysis. Efficacy in terms of pre-dose forced expiratory volume in one second (FEV1) at Week 12 and Week 24/26 (ARISE/SHINE) and FEV1 at 30min and 60min post-dose at Day 1, Week 12, and Week 24/26 was evaluated...
November 2016: Respiratory Investigation
https://www.readbyqxmd.com/read/27882023/effects-of-bisoprolol-in-combination-with-trimetazidine-on-the-treatment-of-heart-failure-and-concomitant-chronic-obstructive-pulmonary-disease
#10
Yuanyuan Ke, Dingli Xu, Minxiong Li, Zenglong Wu, Yongpeng Huang
OBJECTIVE: To evaluate the effects of bisoprolol combined with trimetazidine on the treatment of heart failure patients having concomitant chronic obstructive pulmonary disease (COPD); in comparison with control group treated with standard therapy only. METHODS: A total of 120 heart failure patients having concomitant COPD were selected and randomly divided into a control group and a treatment group according to different treatment methods (n=60). The control group was given continuous low flow oxygen inhalation and inotropic agents, and their cardiac stress was also reduced...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27859913/copd-assessment-test-for-measurement-of-health-status-in-patients-with-idiopathic-pulmonary-fibrosis-a-cross-sectional-study
#11
Toshiaki Matsuda, Hiroyuki Taniguchi, Masahiko Ando, Yasuhiro Kondoh, Tomoki Kimura, Kensuke Kataoka, Koji Sakamoto, Atsushi Suzuki, Taiki Furukawa, Yoshinori Hasegawa
BACKGROUND AND OBJECTIVE: The COPD Assessment Test (CAT) has been reported to have potential utility for measuring health status of idiopathic pulmonary fibrosis (IPF). Although the CAT has been developed for the assessment of COPD patients, it has not been fully evaluated exclusively in IPF. This study was designed to evaluate the validity of the CAT in IPF. METHODS: The clinical data for 106 consecutive subjects with newly diagnosed IPF who completed pulmonary function tests, partial pressure of oxygen in arterial blood (PaO2 ) at rest, 6-min walk test (6MWT), CAT, St George's Respiratory Questionnaire (SGRQ), modified Medical Research Council (mMRC) dyspnoea grade and Hospital Anxiety and Depression Scale (HADS), were analysed...
November 9, 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/27853361/sputum-microbiology-predicts-health-status-in-copd
#12
Dionne Cw Braeken, Sarah Houben-Wilke, Dionne E Smid, Gernot Gu Rohde, Jesse Jc Drijkoningen, Emiel Fm Wouters, Martijn A Spruit, Frits Me Franssen
BACKGROUND: Spontaneous sputum production occurs in a subset of COPD patients; however, its clinical relevance has not been established. Differences in health status and clinical outcomes between patients with and without positive sputum cultures are unknown. OBJECTIVE: To compare clinical characteristics and health status of spontaneous sputum producers with a positive culture (SC+) and negative culture (SC-) with nonsputum producers (NP) in a cohort of COPD patients referred for pulmonary rehabilitation...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27846347/upper-limb-exercise-training-for-copd
#13
REVIEW
Zoe J McKeough, Marcelo Velloso, Vanessa P Lima, Jennifer A Alison
BACKGROUND: People with chronic obstructive pulmonary disease (COPD) often experience difficulty with performing upper limb exercise due to dyspnoea and arm fatigue. Consequently, upper limb exercise training is typically incorporated in pulmonary rehabilitation programmes to improve upper limb exercise capacity; however, the effects of this training on dyspnoea and health-related quality of life (HRQoL) remain unclear. OBJECTIVES: To determine the effects of upper limb training (endurance or resistance training, or both) on symptoms of dyspnoea and HRQoL in people with COPD...
November 15, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27843306/efficacy-and-safety-of-tiotropium-olodaterol-maintenance-treatment-in-patients-with-copd-in-the-tonado-%C3%A2-and-otemto-%C3%A2-studies-a-subgroup-analysis-by-age
#14
Gary T Ferguson, Jill P Karpel, Emmanuelle Clerisme-Beaty, Lars Grönke, Florian Voß, Roland Buhl
BACKGROUND: Increasing age is associated with poor prognosis in patients with COPD. OBJECTIVE: This analysis from the replicate Phase III OTEMTO(®) and TONADO(®) studies examined the efficacy and safety of tiotropium, a long-acting anticholinergic, combined with olodaterol, a long-acting β2-agonist, compared to monotherapies and placebo in patients with COPD aged 40 years to <65 years, 65 years to <75 years, 75 years to <85 years, and ≥85 years. METHODS: In these double-blind, parallel-group, active-controlled, multicenter, randomized studies, patients received tiotropium + olodaterol 2...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27831730/the-importance-of-exercise-self-efficacy-for-clinical-outcomes-in-pulmonary-rehabilitation
#15
Anne-Marie Selzler, Wendy M Rodgers, Tanya R Berry, Michael K Stickland
OBJECTIVE: Pulmonary rehabilitation (PR) improves functional exercise capacity and health status in people with chronic obstructive pulmonary disease (COPD), although these outcomes are often not maintained following PR. Self-efficacy is a precursor to outcomes achievement, yet few studies have examined the importance of self-efficacy to outcome improvement during PR, or how it develops over time. Further, the contribution of exercise-specific self-efficacy to outcomes in PR is unknown...
November 2016: Rehabilitation Psychology
https://www.readbyqxmd.com/read/27817821/consistent-improvement-in-health-related-quality-of-life-with-tiotropium-in-patients-with-chronic-obstructive-pulmonary-disease-novel-and-conventional-responder-analyses
#16
Donald P Tashkin, Eric D Bateman, Paul Jones, Valentina B Zubek, Norbert Metzdorf, Dacheng Liu, Thomas Leonard, Emmanuelle Clerisme-Beaty, Robert A Wise
INTRODUCTION: Improving health-related quality of life (HRQoL) in COPD patients is an important pharmacotherapeutic objective. This study investigated the extent, consistency, and durability of tiotropium maintenance therapy impact on HRQoL in moderate-to-very severe COPD. METHODS: Patients received once-daily tiotropium 18 μg (n = 5244) or placebo (n = 4799) via HandiHaler(®) (10 trials), or once-daily tiotropium 5 μg (n = 2622) or placebo (n = 2618) via Respimat(®) inhaler (3 trials)...
November 2016: Respiratory Medicine
https://www.readbyqxmd.com/read/27805538/-effectiveness-of-the-assessment-of-burden-of-copd-tool-a-cluster-randomised-controlled-trial
#17
O C P van Schayck, A H M Slok, D Kotz, G van Breukelen, N H Chavannes, M P M H Rutten-van Mölken, H A M Kerstjens, T van der Molen, G M Asijee, P N R Dekhuijzen, S Holverda, P L Salomé, L M A Goossens, M Twellaar, J C C M In 't Veen
OBJECTIVE: Assessment of the effectiveness of the Assessment of Burden of COPD (ABC) tool on disease-specific quality of life in patients with Chronic Obstructive Pulmonary Disease (COPD). DESIGN: Cluster-randomised controlled trial. METHOD: This concerned a trial in 39 Dutch primary care practices and 17 hospitals, involving 357 patients with COPD (postbronchodilator FEV1/FVC ratio < 0.7) aged ≥ 40 years. Healthcare providers were randomized to an intervention or control group...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27796912/assessing-short-term-deterioration-in-maintenance-na%C3%A3-ve-patients-with-copd-receiving-umeclidinium-vilanterol-and-tiotropium-a-pooled-analysis-of-three-randomized-trials
#18
M Reza Maleki-Yazdi, Dave Singh, Antonio Anzueto, Lee Tombs, William A Fahy, Ian Naya
INTRODUCTION: Dual bronchodilator therapy is reserved as a second-line treatment in patients with chronic obstructive pulmonary disease (COPD) and provides benefits in lung function and health status versus monotherapy. The aim of this study was to determine whether early initiation of a dual bronchodilator versus monotherapy reduced the risk of deterioration in COPD. METHODS: This post hoc pooled analysis investigated the efficacy and safety of umeclidinium/vilanterol (UMEC/VI) 62...
October 28, 2016: Advances in Therapy
https://www.readbyqxmd.com/read/27785010/efficacy-and-safety-of-indacaterol-glycopyrronium-in-japanese-patients-with-copd-a-subgroup-analysis-from-the-shine-study
#19
Shu Hashimoto, Hisataro Ikeuchi, Shujiro Murata, Tetsuji Kitawaki, Kimitoshi Ikeda, Donald Banerji
BACKGROUND: COPD-related deaths are increasing in Japan, with ~5.3 million people at risk. METHODS: The SHINE was a 26-week, multicenter, randomized, double-blind, parallel-group study that evaluated safety and efficacy of indacaterol (IND)/glycopyrronium (GLY) 110/50 μg once daily (od) compared with GLY 50 μg od, IND 150 μg od, open-label tiotropium (TIO) 18 μg od, and placebo. The primary end point was trough forced expiratory volume in 1 second (FEV1) at Week 26...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27779550/short-and-long-term-effects-of-pulmonary-rehabilitation-in-patients-with-mild-copd-a-comparison-with-patients-with-moderate-to-severe-copd
#20
Cristina Jácome, Alda Marques
PURPOSE: Pulmonary rehabilitation (PR) is effective in patients with moderate to severe chronic obstructive pulmonary disease (COPD). However, the effects of PR in patients with mild COPD have not yet been established. Thus, this study investigated the short- and long-term effects of PR in patients with mild COPD in comparison with patients with moderate to severe disease. METHODS: A total of 32 patients with mild (group 1) and 29 with moderate to severe (group 2) COPD completed the study...
November 2016: Journal of Cardiopulmonary Rehabilitation and Prevention
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