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https://www.readbyqxmd.com/read/29774138/clinical-evaluation-of-morgellons-disease-in-a-cohort-of-north-american-patients
#1
Melissa C Fesler, Marianne J Middelveen, Raphael B Stricker
Morgellons disease (MD) is a dermatological condition characterized by aberrant production of keratin and collagen fibers in skin. Although infection with Borrelia burgdorferi , the causative agent of Lyme disease (LD), has been associated with MD, relatively few studies have hitherto provided epidemiological evidence regarding this association. A cohort of 1000 seropositive North American LD patients was evaluated for the presence of MD. Patients were diagnosed with MD based on detection of microscopic fibers in skin lesions or under unbroken skin...
April 23, 2018: Dermatology Reports
https://www.readbyqxmd.com/read/29728483/what-is-the-risk-of-tickborne-diseases-to-uk-pets
#2
John S P Tulloch
No abstract text is available yet for this article.
May 5, 2018: Veterinary Record
https://www.readbyqxmd.com/read/29723166/vital-signs-trends-in-reported-vectorborne-disease-cases-united-states-and-territories-2004-2016
#3
Ronald Rosenberg, Nicole P Lindsey, Marc Fischer, Christopher J Gregory, Alison F Hinckley, Paul S Mead, Gabriela Paz-Bailey, Stephen H Waterman, Naomi A Drexler, Gilbert J Kersh, Holley Hooks, Susanna K Partridge, Susanna N Visser, Charles B Beard, Lyle R Petersen
INTRODUCTION: Vectorborne diseases are major causes of death and illness worldwide. In the United States, the most common vectorborne pathogens are transmitted by ticks or mosquitoes, including those causing Lyme disease; Rocky Mountain spotted fever; and West Nile, dengue, and Zika virus diseases. This report examines trends in occurrence of nationally reportable vectorborne diseases during 2004-2016. METHODS: Data reported to the National Notifiable Diseases Surveillance System for 16 notifiable vectorborne diseases during 2004-2016 were analyzed; findings were tabulated by disease, vector type, location, and year...
May 4, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29664394/dynamics-of-spirochetemia-and-early-pcr-detection-of-borrelia-miyamotoi
#4
Lyudmila Karan, Marat Makenov, Nadezhda Kolyasnikova, Olga Stukolova, Marina Toporkova, Olga Olenkova
We investigated whether Borrelia miyamotoi disease can be detected in its early stage by using PCR for borrelial 16S rRNA, which molecule (DNA or RNA) is the best choice for this test, and whether spirochetes are present in blood during the acute phase of B. miyamotoi disease. A total of 473 patients with a suspected tickborne infection in Yekaterinburg, Russia, in 2009, 2010, and 2015 were enrolled in this study. Blood samples were analyzed by using quantitative PCR or ELISA, and a diagnosis of borreliosis was confirmed for 310 patients...
May 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29664369/heartland-virus-and-hemophagocytic-lymphohistiocytosis-in-immunocompromised-patient-missouri-usa
#5
Abigail L Carlson, Daniel M Pastula, Amy J Lambert, J Erin Staples, Atis Muehlenbachs, George Turabelidze, Charles S Eby, Jesse Keller, Brian Hess, Richard S Buller, Gregory A Storch, Kathleen Byrnes, Louis Dehner, Nigar Kirmani, F Matthew Kuhlmann
Heartland virus is a suspected tickborne pathogen in the United States. We describe a case of hemophagocytic lymphohistiocytosis, then death, in an immunosuppressed elderly man in Missouri, USA, who was infected with Heartland virus.
May 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29662016/persistent-borrelia-infection-in-patients-with-ongoing-symptoms-of-lyme-disease
#6
Marianne J Middelveen, Eva Sapi, Jennie Burke, Katherine R Filush, Agustin Franco, Melissa C Fesler, Raphael B Stricker
INTRODUCTION: Lyme disease is a tickborne illness that generates controversy among medical providers and researchers. One of the key topics of debate is the existence of persistent infection with the Lyme spirochete, Borrelia burgdorferi , in patients who have been treated with recommended doses of antibiotics yet remain symptomatic. Persistent spirochetal infection despite antibiotic therapy has recently been demonstrated in non-human primates. We present evidence of persistent Borrelia infection despite antibiotic therapy in patients with ongoing Lyme disease symptoms...
April 14, 2018: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/29543607/ce-lyme-disease-diagnosis-treatment-and-prevention
#7
Susan Kane Patton, Bailey Phillips
Evidence-based strategies for nurses. ABSTRACT: Lyme disease is recognized as the most common vector-borne disease in the United States. Surveillance data indicate both increasing numbers of Lyme disease cases and geographic expansion of areas where the causative spirochete, Borrelia burgdorferi, can be found. With prompt diagnosis and appropriate treatment in the acute stage, most patients will recover fully. Without treatment, however, the infecting pathogen remains within the body, often producing long-term complications, including musculoskeletal, neurologic, and cardiovascular effects...
March 14, 2018: American Journal of Nursing
https://www.readbyqxmd.com/read/29383735/transfusion-transmitted-and-community-acquired-babesiosis-in-new-york-2004-to-2015
#8
Jeanne V Linden, Melissa A Prusinski, Lauren A Crowder, Laura Tonnetti, Susan L Stramer, Debra A Kessler, Jennifer White, Beth Shaz, Danuta Olkowska
BACKGROUND: Babesiosis is a potentially life-threatening zoonotic infection most frequently caused by the intraerythrocytic parasite Babesia microti. The pathogen is usually tickborne, but may also be transfusion or vertically transmitted. Healthy persons, including blood donors, may be asymptomatic and unaware they are infected. Immunocompromised patients are at increased risk for symptomatic disease. STUDY DESIGN AND METHODS: All reported community-acquired babesiosis cases in New York from 2004 to 2015 were evaluated, enumerated, and characterized...
March 2018: Transfusion
https://www.readbyqxmd.com/read/29217768/potential-risk-posed-by-the-importation-of-ticks-into-the-uk-on-animals-records-from-the-tick-surveillance-scheme
#9
Kayleigh M Hansford, Maaike E Pietzsch, Benjamin Cull, Emma L Gillingham, Jolyon M Medlock
In order to monitor important tick vectors in the UK, Public Health England's Tick Surveillance Scheme (TSS) receives specimens from across the country for identification. In recent years, an increasing number of these specimens have been removed from animals with a recent history of travel outside the UK. This paper presents all data collated by the TSS on ticks entering the country on recently travelled or imported animals since surveillance commenced in 2005. Ten different tick species representing six different genera were identified, entering the UK from 15 different countries...
January 27, 2018: Veterinary Record
https://www.readbyqxmd.com/read/29148392/acute-myopericarditis-associated-with-tickborne-rickettsia-sibirica-mongolitimonae
#10
Pablo Revilla-Martí, Álvaro Cecilio-Irazola, Jara Gayán-Ordás, Isabel Sanjoaquín-Conde, Jose Antonio Linares-Vicente, José A Oteo
We report an unusual case of myopericarditis caused by Rickettsia sibirica mongolitimonae. Because of increasing reports of Rickettsia spp. as etiologic agents of acute myopericarditis and the ease and success with which it was treated in the patient reported here, rickettsial infection should be included in the differential diagnosis for myopericarditis.
December 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28977771/molecular-surveillance-for-bartonella-borrelia-and-rickettsia-species-in-ticks-from-desert-bighorn-sheep-ovis-canadensis-and-mule-deer-odocoileus-hemionus-in-southern-california-usa
#11
Sarah A Billeter, Lynn M Osikowicz, Joseph E Burns, Lora Konde, Ben J Gonzales, Renjie Hu, Michael Y Kosoy
:  Ticks (Acari: Ixodidae) were collected from 44 desert bighorn sheep ( Ovis canadensis) and 10 mule deer ( Odocoileus hemionus) in southern California, US during health inspections in 2015-16. Specimens were identified and screened by PCR analysis to determine the presence and prevalence of Bartonella, Borrelia, and Rickettsia species in ticks associated with these wild ruminants. None of the 60 Dermacentor hunteri and 15 Dermacentor albipictus ticks tested yielded positive PCR results. Additional tick specimens should be collected and tested to determine the prevalence of these confirmed or suspected tickborne pathogens within ruminant populations...
January 2018: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28930025/unrecognized-subclinical-infection-with-tickborne-encephalitis-virus-japan
#12
Kentaro Yoshii, Reiji Kojima, Hiroshi Nishiura
During early 2017, we conducted a seroepidemiologic investigation for tickborne encephalitis virus among 291 Japan Self-Defense Forces members in Hokkaido. Two (0.7%) tested positive. Neither had clinically apparent symptoms after removing ticks.
October 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28754189/progress-and-works-in-progress-update-on-flavivirus-vaccine-development
#13
REVIEW
Matthew H Collins, Stefan W Metz
Most areas of the globe are endemic for at least one flavivirus, putting billions at risk for infection. This diverse group of viral pathogens causes a range of manifestations in humans from asymptomatic infection to hemorrhagic fever to encephalitis to birth defects and even death. Many flaviviruses are transmitted by mosquitos and have expanded in geographic distribution in recent years, with dengue virus being the most prevalent, infecting approximately 400 million people each year. The explosive emergence of Zika virus in Latin America in 2014 refocused international attention on this medically important group of viruses...
August 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28752214/prevalence-and-risk-factors-associated-with-theileria-parva-infection-in-cattle-in-three-regions-of-tanzania
#14
Isack I Kerario, Martin C Simuunza, Sebastian W Chenyambuga, Marja Koski, Seong-Gu Hwang, Walter Muleya
Ticks and tickborne diseases (TBDs) are serious constraints to cattle production in Tanzania and other tropical and subtropical countries. Among the TBDs, East Coast fever (ECF) is the most important as it causes significant economic losses to the cattle industry in Tanzania. However, control of ECF in Tanzania has continued to be a challenge due to inadequate epidemiological information. The main objective of this study was to determine the epidemiological situation of Theileria parva infections in cattle kept under pastoral and agro-pastoral farming systems in Mara, Singida, and Mbeya regions of Tanzania...
December 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28749278/survey-of-anaplasma-phagocytophilum-antibodies-in-captive-przewalski-s-horses-equus-ferus-przewalskii
#15
Richard R Sim, Luis R Padilla, Priscilla H Joyner, Paul Anikis, Copper Aitken-Palmer
Anaplasma phagocytophilum (formerly Ehrlichia equi ) is a tickborne pathogen of domestic horses and the causative agent of equine granulocytic anaplasmosis. After the occurrence of clinical anaplasmosis in a Przewalski's horse ( Equus ferus przewalskii) housed at the Smithsonian Conservation Biology Institute in 2008, opportunistic serosurveillance of the herd was initiated. From 2008 to 2014, 57 serum samples were collected from 27 individuals (10 males; 17 females). Using indirect immunofluorescent antibody assays for anti- Anaplasma phagocytophilum antibodies, it was determined that prevalence was 53%...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28726610/serologic-evidence-of-powassan-virus-infection-in-patients-with-suspected-lyme-disease-1
#16
Holly M Frost, Anna M Schotthoefer, Angela M Thomm, Alan P Dupuis, Sue C Kehl, Laura D Kramer, Thomas R Fritsche, Yvette A Harrington, Konstance K Knox
Powassan virus (POWV) lineage II is an emerging tickborne flavivirus with an unknown seroprevalence in humans. In a Lyme disease-endemic area, we examined the seroreactivity to POWV in 2 patient cohorts and described the clinical features of the POWV-seroreactive patients. POWV disease might be less neuroinvasive than previously thought.
August 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28700843/autochthonous-crimean-congo-hemorrhagic-fever-in-spain
#17
Anabel Negredo, Fernando de la Calle-Prieto, Eduardo Palencia-Herrejón, Marta Mora-Rillo, Jenaro Astray-Mochales, María P Sánchez-Seco, Esther Bermejo Lopez, Javier Menárguez, Ana Fernández-Cruz, Beatriz Sánchez-Artola, Elena Keough-Delgado, Eva Ramírez de Arellano, Fátima Lasala, Jakob Milla, Jose L Fraile, Maria Ordobás Gavín, Amalia Martinez de la Gándara, Lorenzo López Perez, Domingo Diaz-Diaz, M Aurora López-García, Pilar Delgado-Jimenez, Alejandro Martín-Quirós, Elena Trigo, Juan C Figueira, Jesús Manzanares, Elena Rodriguez-Baena, Luis Garcia-Comas, Olaia Rodríguez-Fraga, Nicolás García-Arenzana, Maria V Fernández-Díaz, Victor M Cornejo, Petra Emmerich, Jonas Schmidt-Chanasit, Jose R Arribas
Crimean-Congo hemorrhagic fever (CCHF) is a widely distributed, viral, tickborne disease. In Europe, cases have been reported only in the southeastern part of the continent. We report two autochthonous cases in Spain. The index patient acquired the disease through a tick bite in the province of Ávila - 300 km away from the province of Cáceres, where viral RNA from ticks was amplified in 2010. The second patient was a nurse who became infected while caring for the index patient. Both were infected with the African 3 lineage of this virus...
July 13, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28696196/tickborne-diseases-other-than-lyme-in-the-united-states
#18
REVIEW
Christa Eickhoff, Jason Blaylock
Tickborne diseases are increasing in the United States, and the geographic range of tick vectors is expanding. Tickborne diseases are challenging to diagnose, as they present with vague symptoms such as fever, constitutional symptoms, and nonspecific laboratory abnormalities. A high degree of clinical suspicion is required to make a diagnosis, as patients often do not recall a tick bite. The availability of laboratory testing for tickborne diseases is limited, especially in the acute setting. Therefore, if a tickborne disease is suspected, empiric therapy should often be initiated before laboratory confirmation of the disease is available...
July 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28696189/appropriate-diagnosis-of-tickborne-infections
#19
EDITORIAL
Brian F Mandell
No abstract text is available yet for this article.
July 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28683059/babesiosis-surveillance-wisconsin-2001-2015
#20
Elizabeth Stein, Lina I Elbadawi, James Kazmierczak, Jeffrey P Davis
Babesiosis is an emerging zoonotic disease caused primarily by Babesia microti, an intraerythocytic protozoan. Babesia microti, like the causal agents for Lyme disease and anaplasmosis, is endemic to the northeastern and upper midwestern United States where it is usually transmitted by the blacklegged tick, Ixodes scapularis. Although babesiosis is usually a mild to moderate illness, older or immunocompromised persons can develop a serious malaria-like illness that can be fatal without prompt treatment. The most common initial clinical signs and symptoms of babesiosis (fever, fatigue, chills, and diaphoresis) are nonspecific and present diagnostic challenges that can contribute to delays in diagnosis and effective treatment with atovaquone and azithromycin (1)...
July 7, 2017: MMWR. Morbidity and Mortality Weekly Report
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