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Novack, Victor

Muhammad Abu Tailakh, Michael Friger, Doron Zahger, Aviel Sidi, Efrat Mazor-Dray, Victor Novack
BACKGROUND: We sought to determine the prevalence of diabetes mellitus (DM) newly diagnosed by elevated glycated hemoglobin (HbA1c) in patients undergoing percutaneous coronary intervention (PCI) and its association with 1-year clinical outcomes. METHODS: We prospectively enrolled consecutive patients undergoing PCI (2011-2013). HbA1c levels were assessed during the index hospitalization and newly diagnosed DM was defined as HbA1c≥6.5% in the absence of the previous diagnosis...
September 21, 2016: European Journal of Internal Medicine
Peter B Smulowitz, Chris Cary, Katherine L Boyle, Victor Novack, Liudvikas Jagminas
Abuse of opioid prescription drugs has become an epidemic across the developed world. Despite the fact that emergency physicians overall account for a small proportion of total opioids prescribed, the number of prescriptions has risen dramatically in the past decade and, to some degree, contributes to the available supply of opioids in the community, some of which are diverted for non-medical use. Since successfully reducing opioid prescribing on the individual level first requires knowledge of current prescribing patterns, we sought to determine to what extent variation exists in opioid prescribing patterns at our institution...
July 16, 2016: Internal and Emergency Medicine
Sarah Rothman, Anat Gonen, Alina Vodonos, Victor Novack, Ilan Shelef
BACKGROUND: Magnetic resonance imaging has been recognized for years as the safest and most precise imaging method, particularly for children. The accuracy of MRI depends on avoidance of patient movement during the study. This may be difficult for children and may require anesthesia. OBJECTIVE: We evaluated an introductory instruction program as an assistive tool in performing MRI without anesthesia. MATERIALS AND METHODS: In one institution, 121 children were randomized to undergo full interactive pre-MRI instruction (n=64), which included an instructional booklet, movie and simulator practice, or partial instruction (n=57), comprised of the booklet only...
October 2016: Pediatric Radiology
Anat Nevo-Shor, Slava Kogan, Ben-Zion Joshua, Anat Bahat-Dinur, Victor Novack, Merav Fraenkel
BACKGROUND: Seasonal variations of 25-hydroxyvitamin D, PTH and calcium levels are not well characterized in primary hyperparathyroidism (PHPT). Our objectives were to characterize seasonal changes in these parameters in PHPT patients, and to assess whether these seasonal changes affect clinical decision making. METHODS: This is a retrospective study based on the electronic medical records of Clalit Health service in the south of Israel between 2000 and 2012. Patients 18years and older with PHPT (PTH>upper limit of norm (ULN) and serum calcium>10...
August 2016: Bone
Irina Meledin, Muhammad Abu Tailakh, Shlomo Gilat, Hagai Yogev, Agneta Golan, Victor Novack, Eilon Shany
OBJECTIVE: To compare amplitude-integrated EEG (aEEG) and conventional EEG (EEG) activity in premature neonates. METHODS: Biweekly aEEG and EEG were simultaneously recorded in a cohort of infants born less than 34 weeks gestation. aEEG recordings were visually assessed for lower and upper border amplitude and bandwidth. EEG recordings were compressed for visual evaluation of continuity and assessed using a signal processing software for interburst intervals (IBI) and frequencies' amplitude...
May 25, 2016: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
Maayan Yitshak Sade, Itai Kloog, Idit F Liberty, Joel Schwartz, Victor Novack
CONTEXT: Evidence from recent decades supports a causal association between air pollution (particulate matter <10 μm in diameter [PM10] and PM <2.5 μm in diameter [PM2.5]) and oxidative stress, possibly involving impaired metabolism of glucose and lipids. OBJECTIVE: Using a satellite based model to assess PM exposure at 1-km spatial resolution, we examined the associations between PM and glucose, hemoglobin A1c (HbA1c), and lipids. DESIGN: Population-based retrospective cohort study of a 10-year period...
June 2016: Journal of Clinical Endocrinology and Metabolism
Elisabeth D Riviello, Willy Kiviri, Robert A Fowler, Ariel Mueller, Victor Novack, Valerie M Banner-Goodspeed, Julia L Weinkauf, Daniel S Talmor, Theogene Twagirumugabe
INTRODUCTION: Intensive Care Unit (ICU) risk prediction models are used to compare outcomes for quality improvement initiatives, benchmarking, and research. While such models provide robust tools in high-income countries, an ICU risk prediction model has not been validated in a low-income country where ICU population characteristics are different from those in high-income countries, and where laboratory-based patient data are often unavailable. We sought to validate the Mortality Probability Admission Model, version III (MPM0-III) in two public ICUs in Rwanda and to develop a new Rwanda Mortality Probability Model (R-MPM) for use in low-income countries...
2016: PloS One
Gal Ifergane, Andrey Ovanyan, Ronen Toledano, Aviv Goldbart, Ibrahim Abu-Salame, Asher Tal, Moshe Stavsky, Victor Novack
BACKGROUND AND PURPOSE: Sleep-disordered breathing is common among patients with stroke resulting in 4- to 6-fold higher prevalence of obstructive sleep apnea (OSA). We prospectively evaluated clinical characteristics and laboratory markers of inflammation and coagulability associated with OSA severity during the acute post stroke period. METHODS: Consecutive patients admitted to the department of Neurology after an acute ischemic stroke were evaluated during the first 48 hours of symptom onset using Watch peripheral arterial tonometry, a wrist-worn ambulatory sleep study device that utilizes peripheral arterial tonometry...
May 2016: Stroke; a Journal of Cerebral Circulation
Lars W Andersen, Mathias J Holmberg, Katherine M Berg, Maureen Chase, Michael N Cocchi, Christopher Sulmonte, Julia Balkema, Mary MacDonald, Sophia Montissol, Venkatachalam Senthilnathan, David Liu, Kamal Khabbaz, Adam Lerner, Victor Novack, Xiaowen Liu, Michael W Donnino
BACKGROUND: Thiamine is a vitamin that is essential for adequate aerobic metabolism. The objective of this study was to determine if thiamine administration prior to coronary artery bypass grafting would decrease post-operative lactate levels as a measure of increased aerobic metabolism. METHODS: We performed a randomized, double-blind, placebo-controlled trial of patients undergoing coronary artery bypass grafting. Patients were randomized to receive either intravenous thiamine (200 mg) or placebo both immediately before and again after the surgery...
2016: Critical Care: the Official Journal of the Critical Care Forum
XiChun Zhang, Andrew M Strassman, Victor Novack, Mitchell F Brin, Rami Burstein
BACKGROUND: Administration of onabotulinumtoxinA (BoNT-A) to peripheral tissues outside the calvaria reduces the number of days chronic migraine patients experience headache. Because the headache phase of a migraine attack, especially those preceded by aura, is thought to involve activation of meningeal nociceptors by endogenous stimuli such as changes in intracranial pressure (i.e. mechanical) or chemical irritants that appear in the meninges as a result of a yet-to-be-discovered sequence of molecular/cellular events triggered by the aura, we sought to determine whether extracranial injections of BoNT-A alter the chemosensitivity of meningeal nociceptors to stimulation of their intracranial receptive fields...
August 2016: Cephalalgia: An International Journal of Headache
Moshe Stavsky, Renana Robinson, Maayan Yitshak Sade, Hanah Krymko, Eli Zalstein, Viktorya Ioffe, Victor Novack, Aviva Levitas
BACKGROUND: The aetiology of conotruncal heart defects is poorly understood and the birth prevalence varies geographically. The known risk factors for developing conotruncal heart defects are as follows: CHD in siblings, genetic chromosomal abnormalities, paternal age >30 years, high parity, low birth weight, prematurity, and maternal diabetes. OBJECTIVE: The aim of this study was to characterise conotruncal heart defects, birth prevalence, mortality, and morbidity in the population of southern Israel, of whom 75% are Jewish and the rest are mostly Bedouin Arabs...
March 16, 2016: Cardiology in the Young
Idit Dotan, Klaris Riesenberg, Ronen Toledano, Francisc Schlaeffer, Alexander Smolyakov, Lisa Saidel-Odes, Oded Wechsberg, Jacob N Ablin, Victor Novack, Dan Buskila
OBJECTIVES: Fibromyalgia and chronic pain have previously associated with HIV infection for over two decades. We aimed to evaluate the prevalence of FMS symptoms in an ethnically heterogeneous population of HIV-infected individuals in southern Israel, applying the proposed new diagnostic criteria for diagnosis of fibromyalgia symdrome (FMS). METHODS: 156 HIV-positive patients followed at the AIDS clinic of the Soroka University Medical Center (SUMC) who gave written informed consent were recruited in the trial...
March 2016: Clinical and Experimental Rheumatology
Ohad Etzion, Victor Novack, Yael Perl, Olga Abel, Doron Schwartz, Daniella Munteanu, Naim Abufreha, Gil Ben-Yaakov, Eyal D Maoz, Alex Moshaklo, Vitaly Dizingf, Alex Fich
BACKGROUND AND AIMS: Response rate to second-generation hepatitis B virus vaccines is relatively low in patients with inflammatory bowel diseases compared with the general healthy population. We compared the efficacy and safety of a third- vs a second-generation hepatitis B virus vaccine in a group of patients with inflammatory bowel diseases treated with immunosuppressive medications. METHODS: Prospective, randomised, single-blind, controlled study. Eligible patients were randomly assigned to receive one of two vaccines, ENGERIX-B or Sci-B-Vac...
August 2016: Journal of Crohn's & Colitis
Yuval Konstantino, Tali Shafat, Victor Novack, Lena Novack, Guy Amit
BACKGROUND: Implantable cardioverter defibrillators (ICDs) reduce mortality in patients implanted for primary and secondary prevention of sudden cardiac death. Data on the incidence of appropriate ICD therapies in primary vs. secondary prevention are limited. OBJECTIVES: To compare ICD therapies and mortality in primary vs. secondary prevention of sudden cardiac death. METHODS: We conducted a retrospective analysis of 581 consecutive patients receiving an ICD for primary (66%) or secondary (34%) prevention indications...
December 2015: Israel Medical Association Journal: IMAJ
Or Kalchiem-Dekel, Roi Westreich, Adi Regev, Victor Novack, Mordechai Goldberg, Nimrod Maimon
OBJECTIVES/HYPOTHESIS: Snoring and excessive daytime sleepiness (EDS) are major obstructive sleep apnea (OSA) symptoms. Snorers with apnea/hypopnea index < 5 are designated "simple snorers" and do not meet OSA criteria. This study aimed to explore a possible association between snoring intensity and EDS defined as Epworth Sleepiness Scale (ESS) scores ≥ 11 in non-OSA subjects. STUDY DESIGN: Prospective cohort study. METHODS: From a total of 2,225 subjects who underwent polysomnography (PSG), 307 simple snorers qualified for the study and were assessed for snoring intensity and ESS score...
July 2016: Laryngoscope
Galia Karp, Arik Wolak, Yael Baumfeld, Nina Bar-Am, Victor Novack, Talya Wolak, Lior Fuchs, Aryeh Shalev, Ilan Shelef, Mahmoud Abu-Shakra
To evaluate aortic stiffness by MRI in female patients with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA) in comparison to controls. We measured aortic strain, distensibility and pulse wave velocity (PWV) by MRI in 30 SLE patients, 31 RA patients and 53 matched controls. Mean PWV in SLE and RA patients were higher in comparison to controls (9.2 ± 4.4 vs. 7.6 ± 3.0 m/s, p = 0.04) and (6.2 ± 2.3 vs. 5.4 ± 1.7, p = 0.04) respectively. Aortic distensibility among RA patients was significantly lower in comparison to controls (4...
June 2016: International Journal of Cardiovascular Imaging
Alex Kazberouk, Iftach Sagy, Victor Novack, Kevin McGuire
STUDY DESIGN: Retrospective analysis of billing data, medical records, and hospital cost data. OBJECTIVE: To quantify intersurgeon variation for hospital costs of four spine procedures while adjusting for patient comorbidities and demographic factors. SUMMARY OF BACKGROUND DATA: Spine care accounts for $90 billion in health care expenditures in the United States. Past findings demonstrate regional variation in surgery rates and high intersurgeon variation for anterior cervical discectomies/fusions...
July 1, 2016: Spine
Tomer Tzadok, Ronen Toledano, Lior Fuchs, Carmi Bartal, Victor Novack, Gal Ifergane
BACKGROUND: Headache is a frequent symptom of many systemic diseases that do not involve cranial structures. In this observational study, we assessed factors associated with headache in the acute presentation of systemic conditions in a nonsurgical emergency department (ED). METHODS: Consecutive patients, admitted to Soroka University Medical Center ED due to noncephalic illness, were prospectively surveyed using a structured questionnaire focused on the prevalence and characteristics of headache symptoms...
October 2015: Journal of Neurosciences in Rural Practice
Daniel J Henning, Jeremy R Carey, Kimie Oedorf, Danielle E Day, Colby S Redfield, Colin J Huguenel, Jonathan C Roberts, Victor Novack, Leon D Sanchez, Richard E Wolfe, Nathan I Shapiro
INTRODUCTION: Differentiating shock etiologies is a challenging task in the Emergency Department (ED); even the strongest clinical predictors leave some diagnostic uncertainty. This study sought to establish an evidence base for using clinical covariates in the diagnostic evaluation of septic shock. METHODS: We conducted a prospective, observational study of consecutive ED patients with shock from November 11, 2012 to September 23, 2013. We included all patients at least 18 years old with shock, defined as new vasopressor requirement, systolic blood pressure less than 90 mmHg after at least 1 L of crystalloid or 2 units packed red blood cells, or systolic blood pressure less than 90 mmHg and fluids withheld due to concern for fluid overload...
July 2016: Shock
Joshua S Easter, Jason S Haukoos, William P Meehan, Victor Novack, Jonathan A Edlow
IMPORTANCE: Adults with apparently minor head trauma (Glasgow Coma Scale [GCS] scores ≥13 who appear well on examination) may have severe intracranial injuries requiring prompt intervention. Findings from clinical examination can aid in determining which adults with minor trauma have severe intracranial injuries visible on computed tomography (CT). OBJECTIVE: To assess systematically the accuracy of symptoms and signs in adults with minor head trauma in order to identify those with severe intracranial injuries...
December 22, 2015: JAMA: the Journal of the American Medical Association
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