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Novack, Victor

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https://www.readbyqxmd.com/read/29859014/medical-cannabis-aligning-use-to-evidence-based-medicine-approach
#1
REVIEW
Lihi Bar-Lev Schleider, Ran Abuhasira, Victor Novack
During the last decade we are witnessing a rise in medical cannabis use, yet the evidence for the safety and effectiveness of the different cannabinoid compounds is scarce. We believe that the role of the clinical research community is to identify the potential benefit of the new compounds under the Evidence Based Medicine paradigm. In this editorial review we shall present a summary of selected evidence of safety and efficacy of cannabis derived products with an emphasis on prospective studies in Israel.
June 2, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29843639/lessons-learned-from-the-2009-2010-h1n1-outbreak-for-the-management-of-the-2013-silent-polio-outbreak
#2
Iftach Sagy, Paula Feder-Bubis, Victor Novack, Tal Peleg-Sagy, Dan Greenberg
BACKGROUND: The Israeli Ministry of Health (MoH) encountered two substantial outbreaks during the past decade: the H1N1 swine flu outbreak during 2009-2010 and the silent polio outbreak during 2013. Although both outbreaks share several similar characteristics, the functioning of the Israeli MoH was different for each case. The aim of this study was to identify factors that contributed to the change in the MoH response to the polio outbreak in light of the previous 2009-2010 H1N1 outbreak...
May 29, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29742586/long-term-survival-of-young-patients-surviving-icu-admission-with-severe-sepsis
#3
Heba Abu-Kaf, Yuval Mizrakli, Victor Novack, Jacob Dreiher
OBJECTIVES: Sepsis remains a disease with a high mortality rate. The study goal was to assess long-term survival of severe sepsis in young patients. DESIGN: Retrospective cohort study. SETTING: Patients admitted with sepsis to ICUs in seven tertiary hospitals between 2003 and 2011. PATIENTS: A total of 409 patients less than 45 years who survived to hospital discharge were age and sex matched with 818 patients with infectious disease without sepsis selected from internal medicine or surgical department admissions...
May 7, 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29728012/increase-in-ischemic-stroke-incident-hospitalizations-among-bedouin-arabs-during-ramadan-month
#4
Noa Zimhony, Ibrahim Abu-Salameh, Iftach Sagy, Yotam Dizitzer, Liat Oxman, Maayan Yitshak-Sade, Victor Novack, Anat Horev, Gal Ifergane
BACKGROUND: Previous studies have not shown any significant effect on stroke incidence during Ramadan. We aimed to investigate the association between ischemic stroke incident hospitalizations and Ramadan, accounting for seasonality and temperature. METHODS AND RESULTS: This retrospective cohort study included all patients admitted with acute ischemic stroke to Soroka University Medical Center from June 2012 to June 2016. We obtained daily mean temperatures and relative humidity rates from 2 monitoring stations in South Israel...
May 3, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29696826/lung-ultrasound-compared-to-chest-x-ray-for-diagnosis-of-pediatric-pneumonia-a-meta-analysis
#5
REVIEW
Daniel S Balk, Christine Lee, Jesse Schafer, Jeremy Welwarth, John Hardin, Victor Novack, Shaked Yarza, Beatrice Hoffmann
OBJECTIVE: Although a clinical diagnosis, the standard initial imaging modality for patients with concern for pediatric community acquired pneumonia (pCAP) is a chest x-ray (CXR), which has a relatively high false negative rate, exposes patients to ionizing radiation, and may not be available in resource limited settings. The primary objective of this meta-analysis is to evaluate the accuracy of lung ultrasound (LUS) compared to CXR for the diagnosis of pCAP. METHODS: Data were collected via a systematic review of PubMed, EMBASE, and Web of Science with dates up to August 2017...
April 26, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29661659/the-association-between-heat-waves-and-other-meteorological-parameters-and-snakebites-israel-national-study
#6
Sagi Shashar, Maayan Yitshak-Sade, Roman Sonkin, Victor Novack, Eli Jaffe
BACKGROUND: Published annual estimates report a global burden of 2.5 million snakebite cases and >100,000 deaths. In Israel, envenomations are the third most frequent cause of poisonings that are of moderate to major clinical severity. Most studies focus on the clinical descriptions of snakebites in tropical climates, and we sought to investigate the association between snakebite frequency and meteorological parameters. OBJECTIVE: We sought to investigate the seasonality of snakebites and evaluate the association between increasingly common heat waves and other meteorological parameters and snakebite frequency in a semiarid nontropical climate...
June 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29624524/blood-pressure-coefficient-of-variation-and-its-association-with-cardiac-surgical-outcomes
#7
Sayuri P Jinadasa, Ariel Mueller, Varesh Prasad, Kathirvel Subramaniam, Thomas Heldt, Victor Novack, Balachundhar Subramaniam
BACKGROUND: Multiple studies completed in the ambulatory nonsurgical setting show a significant association between short- and long-term blood pressure variability and poor outcomes. However, perioperative blood pressure variability outcomes have not been well studied, especially in the cardiac surgical setting. In this study, we sought to assess whether systolic and mean arterial blood pressure variability were associated with 30-day mortality and in-hospital renal failure in patients undergoing cardiac surgery requiring cardiopulmonary bypass...
April 5, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29482741/prospective-analysis-of-safety-and-efficacy-of-medical-cannabis-in-large-unselected-population-of-patients-with-cancer
#8
Lihi Bar-Lev Schleider, Raphael Mechoulam, Violeta Lederman, Mario Hilou, Ori Lencovsky, Oded Betzalel, Liat Shbiro, Victor Novack
BACKGROUND: Cancer is a major public health problem as the leading cause of death. Palliative treatment aimed to alleviate pain and nausea in patients with advanced disease is a cornerstone of oncology. In 2007, the Israeli Ministry of Health began providing approvals for medical cannabis for the palliation of cancer symptoms. The aim of this study is to characterize the epidemiology of cancer patients receiving medical cannabis treatment and describe the safety and efficacy of this therapy...
March 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29482738/medical-cannabis-what-physicians-need-to-know
#9
EDITORIAL
Victor Novack
No abstract text is available yet for this article.
March 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29445225/atrial-fibrillation-characteristics-in-patients-on-haemodialysis-vs-peritoneal-dialysis
#10
Ran Abuhasira, Yuval Mizrakli, Avi Shimony, Victor Novack, Alla Shnaider, Yosef S Haviv
Atrial fibrillation (AF) is highly prevalent in dialysis patients, however whether its impact differs between patients on haemodialysis (HD) vs. peritoneal dialysis (PD) is unknown. We aimed to compare the association of AF and clinical outcomes in different dialysis modalities. We performed a population based retrospective cohort study, including adult patients who initiated dialysis between the years 2002 and 2015. Clinical, echocardiographic and laboratory data were reviewed and correlated with outcomes in HD vs...
February 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29439866/mass-media-effect-on-vaccines-uptake-during-silent-polio-outbreak
#11
Iftach Sagy, Victor Novack, Michael Gdalevich, Dan Greenberg
BACKGROUND: During 2013, isolation of a wild type 1 poliovirus from routine sewage sample in Israel, led to a national OPV campaign. During this period, there was a constant cover of the outbreak by the mass media. AIMS: To investigate the association of media exposure and OPV and non-OPV vaccines uptake during the 2013 silent polio outbreak in Israel. METHODS: We received data on daily immunization rates during the outbreak period from the Ministry of Health (MoH)...
March 14, 2018: Vaccine
https://www.readbyqxmd.com/read/29398248/epidemiological-characteristics-safety-and-efficacy-of-medical-cannabis-in-the-elderly
#12
Ran Abuhasira, Lihi Bar-Lev Schleider, Raphael Mechoulam, Victor Novack
INTRODUCTION: There is a substantial growth in the use of medical cannabis in recent years and with the aging of the population, medical cannabis is increasingly used by the elderly. We aimed to assess the characteristics of elderly people using medical cannabis and to evaluate the safety and efficacy of the treatment. METHODS: A prospective study that included all patients above 65 years of age who received medical cannabis from January 2015 to October 2017 in a specialized medical cannabis clinic and were willing to answer the initial questionnaire...
March 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29394398/response
#13
Iftach Sagy, Vladimir Zeldetz, Muhammad Abu-Tailakh, Victor Novack
No abstract text is available yet for this article.
January 31, 2018: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29385542/the-association-between-the-patient-and-the-physician-genders-and-the-likelihood-of-intensive-care-unit-admission-in-hospital-with-restricted-icu-bed-capacity
#14
Iftach Sagy, Lior Fuchs, Yuval Mizrakli, Shlomi Codish, Liran Politi, Lior Fink, Victor Novack
Background: Despite the evidence that the patient gender is an important component in the intensive care unit (ICU) admission decision, the role of physician gender and the interaction between the two remain unclear. Objective: To investigate the association of both the patient and the physician gender with ICU admission rate of critically-ill emergency department (ED) medical patients in a hospital with restricted ICU bed capacity operates with "closed door" policy...
January 27, 2018: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29316924/association-of-hospice-utilization-and-publicly-reported-outcomes-following-hospitalization-for-pneumonia-or-heart-failure-a-retrospective-cohort-study
#15
Soowhan Lah, Emily L Wilson, Sarah Beesley, Iftach Sagy, James Orme, Victor Novack, Samuel M Brown
BACKGROUND: The Center for Medicare and Medicaid Services (CMS) and the Hospital Quality Alliance began collecting and reporting United States hospital performance in the treatment of pneumonia and heart failure in 2008. Whether the utilization of hospice might affect CMS-reported mortality and readmission rates is not known. METHODS: Hospice utilization (mean days on hospice per decedent) for 2012 from the Dartmouth Atlas (a project of the Dartmouth Institute that reports a variety of public health and policy-related statistics) was merged with hospital-level 30-day mortality and readmission rates for pneumonia and heart failure from CMS...
January 9, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29079374/estimations-of-a-degree-of-steroid-induced-leukocytosis-in-patients-with-acute-infections
#16
Amit Frenkel, Eric Kachko, Karin Cohen, Victor Novack, Nimrod Maimon
BACKGROUND: Glucocorticosteroids (GCS) are known to cause the hematologic effect of leukocytosis and neutrophilia. Leukocytosis is a key parameter in establishing the diagnosis of sepsis and in the estimation of its severity. OBJECTIVE: To quantify the effect of chronic or acute GCS treatment on the level of leukocytosis in patients with acute infectious process. METHODS: We conducted a retrospective cohort study of patients with an acute infection hospitalized in tertiary medical center between the years 2003-2014...
May 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29077789/benzodiazepine-consumption-is-associated-with-lower-blood-pressure-in-ambulatory-blood-pressure-monitoring-abpm-retrospective-analysis-of-4938-abpms
#17
Nitsan Mendelson, Bella Gontmacher, Allina Vodonos, Victor Novack, Muhammad Abu-AjAj, Arik Wolak, Haddar Shalev, Talya Wolak
BACKGROUND: The effect of chronic benzodiazepine use on blood pressure has not been documented. We aimed to evaluate whether regular benzodiazepine use can be associated to the results of ambulatory blood pressure monitoring (ABPM). METHODS: A retrospective analysis of the ABPM database between 2009 and 2015 was performed. The study groups were divided according to benzodiazepine treatment at least 3 months before ABPM. Generalized estimating equation (GEE) model analysis was conducted to estimate the association between benzodiazepine treatment and ABPM test measurements...
March 10, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/28965037/characteristics-and-outcomes-of-critically-ill-medical-patients-admitted-to-a-tertiary-medical-center-with-restricted-icu-bed-capacity
#18
Iftach Sagy, Lior Fuchs, Yuval Mizrakli, Shlomi Codish, Liran Politi, Lior Fink, Victor Novack
BACKGROUND: In the emergency department (ED) critically-ill medical patients are treated in the resuscitation room (RR). No studies described the outcomes of critically-ill RR patients admitted to a hospital with low capacity of intensive care unit (ICU) beds. METHODS: We included all medical patients above 18 who were admitted to a RR of a tertiary hospital during 2011-2012. We conducted multivariate logistic and Cox regressions and propensity score (PS) matched analysis to analyze parameters associated with the study outcomes...
February 2018: Journal of Critical Care
https://www.readbyqxmd.com/read/28957341/efficacy-and-safety-of-sequential-versus-quadruple-therapy-as-second-line-treatment-for-helicobacter-pylori-infection-a-randomized-controlled-trial
#19
RANDOMIZED CONTROLLED TRIAL
Daniela Munteanu, Ohad Etzion, Gil Ben-Yakov, Daniel Halperin, Leslie Eidelman, Doron Schwartz, Victor Novack, Naim Abufreha, Pavel Krugliak, Alexander Rozenthal, Nava Gaspar, Alexander Moshkalo, Vitaly Dizingof, Alexander Fich
BACKGROUND AND AIMS: Quadruple therapy is recommended as second-line treatment for Helicobacter pylori eradication failure. However, high cost, multiple side effects, and low adherence rates are major drawbacks to its routine use. Our aim was to compare the efficacy and safety of sequential versus quadruple regimens as second line treatment for persistent Helicobacter pylori infection. METHODS: Prospective, randomized, open label trial was conducted at a large academic, tertiary care center in Israel...
2017: PloS One
https://www.readbyqxmd.com/read/28869099/impact-of-implementation-of-the-heart-pathway-using-an-electronic-clinical-decision-support-tool-in-a-community-hospital-setting
#20
Peter B Smulowitz, Yotam Dizitzer, Sarah Tadiri, Lara Thibodeau, Liudvikas Jagminas, Victor Novack
No abstract text is available yet for this article.
March 2018: American Journal of Emergency Medicine
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