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https://www.readbyqxmd.com/read/27902230/roseitalea-porphyridii-gen-nov-sp-nov-isolated-from-a-red-alga-and-reclassification-of-hoeflea-suaedae-chung-et-al-2013-as-pseudohoeflea-suaedae-gen-nov-comb-nov
#1
Jong Woo Hyeon, Sang Eun Jeong, Kyunghwa Baek, Che Ok Jeon
A Gram-staining-negative, strictly aerobic bacterial strain, designated MA7-20T, was isolated from a marine alga, Porphyridium marinum, in Korea. Cells showing oxidase-positive and catalase-positive activities were motile rods with bipolar flagella. Growth of strain MA7-20T was observed at 15-45 C (optimum, 30-37 C), at pH 6.0-10.5 (optimum, pH 7.0-8.0) and in the presence of 0-7 % (w/v) NaCl (optimum, 2-3 %). Strain MA7-20T contained summed feature 8 (comprising C18:1 ω7c/C18:1 ω6c) and 11-methyl-C18:1 ω7c and C18:0 as the major fatty acids and ubiquinone-10 as the sole isoprenoid quinone...
November 2, 2016: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/27900342/cacna1c-protecting-young-hippocampal-neurons-in-the-adult-brain
#2
Héctor De Jesús-Cortés, Anjali M Rajadhyaksha, Andrew A Pieper
Neuropsychiatric disease is the leading cause of disability in the United States, and fourth worldwide.(1,2) Not surprisingly, human genetic studies have revealed a common genetic predisposition for many forms of neuropsychiatric disease, potentially explaining why overlapping symptoms are commonly observed across multiple diagnostic categories. For example, the CACNA1C gene was recently identified in the largest human genome-wide association study to date as a risk loci held in common across 5 major forms of neuropsychiatric disease: bipolar disorder, schizophrenia, major depressive disorder (MDD), autism spectrum disorder and attention deficit-hyperactivity disorder...
2016: Neurogenesis (Austin, Tex.)
https://www.readbyqxmd.com/read/27889598/association-between-antipsychotic-drug-use-and-cataracts-in-patients-with-bipolar-disorder-a-population-based-nested-case-control-study
#3
Che-Sheng Chu, Po-Han Chou, Yi-Huei Chen, Min-Wei Huang, Min-Yen Hsu, Tsuo-Hung Lan, Ching-Heng Lin
BACKGROUND: No previous study has focused on the association between use of antipsychotic drugs and the development of cataracts in patients with bipolar disorder (BD); hence, we aimed to examine this association in the present study. METHODS: We conducted a retrospective nested case-control study using data from the National Health Insurance Database of Taiwan between 2000 and 2011. A total of 3292 BD patients, 1684 with cataracts and 1608 controls matched for age, sex, and index date, were included...
November 19, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27889597/is-there-any-association-between-toxoplasma-gondii-infection-and-bipolar-disorder-a-systematic-review-and-meta-analysis
#4
João Luís Vieira Monteiro de Barros, Izabela Guimarães Barbosa, Haitham Salem, Natalia Pessoa Rocha, Arthur Kummer, Olaoluwa O Okusaga, Jair C Soares, Antonio Lucio Teixeira
BACKGROUND: The relationship between Toxoplasma gondii infection and the development of bipolar disorder (BD) has long been investigated, yet to date it is still poorly understood and documented. The aim of this review is to derive a summary estimate of the strength of the association between infection with T. gondii and BD from the available published studies. METHODS: A systematic review was performed using PubMed, LILACS, PsycINFO, and Embase databases. Studies which included a proportion of seropositive BD patients and controls were further examined in a meta-analysis...
November 17, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27886327/in-situ-tem-observation-on-the-interface-type-resistive-switching-by-electrochemical-redox-reactions-at-a-tin-pcmo-interface
#5
Kyungjoon Baek, Sangsu Park, Jucheol Park, Young-Min Kim, Hyunsang Hwang, Sang Ho Oh
The interface-type resistive switching devices exhibiting bipolar and multi-level resistive switching have been considered as the key component for neuromorphic device applications. To directly observe the microscopic details of underlying electrochemical redox reactions occuring at a metal/oxide interface, we implemented in situ resistive switching of TiN/Pr0.7Ca0.3MnO3 (PCMO)/Pt junction devices in a transmission electron microscope (TEM). The in situ TEM observations directly show that an intermediate reaction layer (TiOxNy), growing and shrinking in the thickness range of a few nanometers at the TiN/PCMO interface in response to the applied voltage, mainly determines the device resistance by limiting the transport of charge carriers via the Poole-Frenkel conduction mechanism...
November 25, 2016: Nanoscale
https://www.readbyqxmd.com/read/27870504/chronic-licl-pretreatment-suppresses-thrombin-stimulated-intracellular-calcium-mobilization-through-trpc3-in-astroglioma-cells
#6
Takuji Uemura, Marty Green, Jerry J Warsh
OBJECTIVES: Transient receptor potential canonical type 3 (TRPC3) channels are activated in B lymphoblast cell lines from patients with bipolar disorder (BD), and its expression is reduced by chronic lithium treatment, implicating TRPC3 in the intracellular calcium (Ca(2+) ) dyshomeostasis of BD. Thrombin, via a protease-activated receptor, moderates Ca(2+) signaling and TRPC3 in astrocytes, and also cell proliferation. We examined whether lithium pretreatment attenuates thrombin-stimulated TRPC3 expression and function in astrocytes, and levels of the calcium-binding peptide, S100B, which is expressed mainly in these cells...
November 2016: Bipolar Disorders
https://www.readbyqxmd.com/read/27865605/population-pharmacokinetic-model-of-lithium-and-drug-compliance-assessment
#7
Isabel Pérez-Castelló, Víctor Mangas-Sanjuan, Ignacio González-García, Isabel Gonzalez-Alvarez, Marival Bermejo, Jose Luis Marco-Garbayo, Iñaki F Trocóniz
Population pharmacokinetic analysis of lithium during therapeutic drug monitoring and drug compliance assessment was performed in 54 patients and 246 plasma concentrations levels were included in this study. Patients received several treatment cycles (1-9) and one plasma concentration measurement for each patient was obtained always before starting next cycle (pre-dose) at steady state. Data were analysed using the population approach with NONMEM version 7.2. Lithium measurements were described using a two-compartment model (CL/F=0...
November 16, 2016: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27862748/-potential-of-a-no-touch-pincer-ablation-procedure-that-uses-a-multipolar-radiofrequency-ablation-system-to-prevent-intra-subsegmental-recurrence-of-small-and-single-hepatocellular-carcinomas
#8
Yusuke Kawamura, Kenji Ikeda, Shunichiro Fujiyama, Tetsuya Hosaka, Masahiro Kobayashi, Satoshi Saitoh, Hitomi Sezaki, Norio Akuta, Fumitaka Suzuki, Yoshiyuki Suzuki, Yasuji Arase, Hiromitsu Kumada
OBJECTIVE: The aim of this study was to clarify the usefulness of a no-touch pincer ablation procedure that uses bipolar electrodes to prevent intra-subsegmental tumor recurrence after radiofrequency ablation (RFA) for patients with hepatocellular carcinoma (HCC). METHODS: We studied 303 consecutive patients with HCC (single nodule and tumor diameter of ≤30 mm) who received RFA between January 2005 and April 2015; 268 patients received touch ablation using a monopolar or bipolar RFA device, and 35 received no-touch ablation using a bipolar RFA device...
November 15, 2016: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/27857778/state-of-acute-agitation-at-psychiatric-emergencies-in-europe-the-stage-study
#9
Luis San, Josef Marksteiner, Peter Zwanzger, María Aragüés Figuero, Francisco Toledo Romero, Grigorios Kyropoulos, Alberto Bessa Peixoto, Roxana Chirita, Anca Boldeanu
BACKGROUND: Agitation is an array of syndromes and types of behaviors that are common in patients with psychiatric disorders. In Europe, the estimation of prevalence of agitation has been difficult due to the lack of standard studies or systematic data collection done on this syndrome. OBJECTIVE: An observational, cross-sectional, multicenter study aimed to assess the prevalence of agitation episodes in psychiatric emergencies in different European countries. METHOD: For 1 week, all episodes of acute agitation that were attended to at the psychiatric emergency room (ER) or Acute Inpatient Unit (AIU) in the 27 participating centers were registered...
2016: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/27856157/the-serological-evidence-for-maternal-influenza-as-risk-factor-for-psychosis-in-offspring-is-insufficient-critical-review-and-meta-analysis
#10
REVIEW
Jean-Paul Selten, Fabian Termorshuizen
Maternal influenza during pregnancy has been suggested to increase the psychosis risk for the offspring. This hypothesis has been tested using "ecological" studies, which examined the risk for individuals born after epidemics, and "serological" studies, based on serological evidence. A study of the latter type obtained an increased schizophrenia risk for individuals exposed during the first trimester. A second study found a relationship between influenza at any time during gestation and risk for bipolar disorder with psychotic features...
November 14, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27855101/long-term-cost-effectiveness-of-collaborative-care-vs-usual-care-for-people-with-depression-and-comorbid-diabetes-or-cardiovascular-disease-a-markov-model-informed-by-the-coincide-randomised-controlled-trial
#11
Elizabeth M Camacho, Dionysios Ntais, Peter Coventry, Peter Bower, Karina Lovell, Carolyn Chew-Graham, Clare Baguley, Linda Gask, Chris Dickens, Linda M Davies
OBJECTIVES: To evaluate the long-term cost-effectiveness of collaborative care (vs usual care) for treating depression in patients with diabetes and/or coronary heart disease (CHD). SETTING: 36 primary care general practices in North West England. PARTICIPANTS: 387 participants completed baseline assessment (collaborative care: 191; usual care: 196) and full or partial 4-month follow-up data were captured for 350 (collaborative care: 170; usual care: 180)...
October 7, 2016: BMJ Open
https://www.readbyqxmd.com/read/27853943/endocardial-voltage-mapping-of-pulmonary-veins-with-an-ultra-high-resolution-system-to-evaluate-atrial-myocardial-extensions
#12
Francesco Santoro, Christian Sohns, Ardan M Saguner, Natale Daniele Brunetti, Christine Lemes, Shibu Mathew, Christian-H Heeger, Bruno Reißmann, Tilman Maurer, Johannes Riedl, Thomas Fink, Kentaro Hayashi, Feifan Ouyang, Matteo Di Biase, Karl-Heinz Kuck, Andreas Metzner
INTRODUCTION: Atrial fibrillation (AF) is mainly triggered by arrhythmogenic foci originating from atrial myocardial extensions (MEs) into the pulmonary veins (PVs). Aim of the study was to evaluate endocardial voltage maps of PVs as a surrogate parameter for the extent of MEs in subjects with AF through a ultra-high-density mapping system. METHODS: Sixty-four bipolar electrograms were recorded simultaneously from the Orion mini-basket catheter placed in 72 PVs of 18 consecutive patients with paroxysmal/persistent AF undergoing PV isolation (PVI)...
November 16, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27846411/binge-eating-disorder-and-bipolar-spectrum-disorders-in-obesity-psychopathological-and-eating-behaviors-differences-according-to-comorbidities
#13
Cristina Segura-Garcia, Mariarita Caroleo, Marianna Rania, Elvira Barbuto, Flora Sinopoli, Matteo Aloi, Franco Arturi, Pasquale De Fazio
BACKGROUND: Obesity is not a mental disorder, yet DSM-5 recognizes a strong association between obesity and psychiatric syndromes. Disorders within the Bipolar Spectrum (BSD) and Binge Eating Disorder (BED) are the most frequent psychiatric disorders among obese patients. The aim of this research is to investigate the psychopathological differences and the distinctive eating behaviors that accompany these comorbidities in obese patients. METHODS: One hundred and nineteen obese patients (40 males; 79 females) underwent psychological evaluation and psychiatric interview, and a dietitian evaluated their eating habits...
November 10, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27835645/pocos-population-covering-locus-sets-for-risk-assessment-in-complex-diseases
#14
Marzieh Ayati, Mehmet Koyutürk
: Susceptibility loci identified by GWAS generally account for a limited fraction of heritability. Predictive models based on identified loci also have modest success in risk assessment and therefore are of limited practical use. Many methods have been developed to overcome these limitations by incorporating prior biological knowledge. However, most of the information utilized by these methods is at the level of genes, limiting analyses to variants that are in or proximate to coding regions...
November 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27813593/case-report-case-study-of-a-patient-presenting-both-type-ii-bipolar-affective-disorder-and-klinefelter-syndrome
#15
H Delavenne, J M Khoury, F Thibaut, F D Garcia
Klinefelter syndrome (KS) is the most common sex chromosomal disorder with an estimated prevalence of 1 in 500-1000. Increased incidences of anxiety, depression, substance abuse, psychotic and behavioral disorders, and sexual disorders have been reported in patients with KS. The aim of this case study was to report a case of a man with untreated KS who was also diagnosed with type II bipolar disorder. This case report raises awareness regarding psychiatric diagnoses that may be associated with such a highly prevalent condition...
October 17, 2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27792673/radial-head-arthroplasty-a-systematic-review
#16
Andras Heijink, Izaäk F Kodde, Paul G H Mulder, Ewout S Veltman, Laurens Kaas, Michel P J van den Bekerom, Denise Eygendaal
BACKGROUND: Despite the expanding body of literature on radial head arthroplasty, the increasing understanding of elbow anatomy, biomechanics, and kinetics, and the evolution of surgical techniques and prosthesis designs, there is currently no evidence to support one type of radial head prosthesis over another. The purposes of the present report were to review the literature and to explore the association between prosthesis design variables and the timing of surgery and the outcome of modern radial head arthroplasty...
October 18, 2016: JBJS Reviews
https://www.readbyqxmd.com/read/27783555/integrated-pharmacies-at-community-mental-health-centers-medication-adherence-and-outcomes
#17
W Abel Wright, Jack M Gorman, Melissa Odorzynski, Mark J Peterson, Carol Clayton
BACKGROUND: Patients receiving psychiatric services at community mental health centers (CMHCs) are often prescribed medication that is critical to the treatment of behavioral health conditions, including schizophrenia, bipolar disorder, anxiety, and depression. Previous studies have shown correlation between rates of medication adherence and risk of hospitalization, but potential differences in medication adherence and other outcomes for patients of CMHCs by pharmacy type have not been widely studied...
November 2016: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/27747715/coma-after-quetiapine-fumarate-intentional-overdose-in-a-71-year-old-man-a-case-report
#18
S Gibiino, A Trappoli, B Balzarro, A R Atti, D De Ronchi
A 71-year-old man developed coma with severe respiratory failure, hypotension, and tachycardia induced by the intentional ingestion of quetiapine fumarate extended release (XR) 20 g. At the time, he had been treated for bipolar depression with venlafaxine 75 mg/day, lamotrigine 100 mg/day, pregabalin 75 mg/day, and quetiapine XR 400 mg/day for approximately 1 year. Comorbidities were hypertension treated with metoprolol, diabetes mellitus type 2 treated with metformin, and benign prostatic hyperplasia treated with silodosin...
December 2015: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/27746508/understanding-and-control-of-bipolar-self-doping-in-copper-nitride
#19
Angela N Fioretti, Craig P Schwartz, John Vinson, Dennis Nordlund, David Prendergast, Adele C Tamboli, Christopher M Caskey, Filip Tuomisto, Florence Linez, Steven T Christensen, Eric S Toberer, Stephan Lany, Andriy Zakutayev
Semiconductor materials that can be doped both n-type and p-type are desirable for diode-based applications and transistor technology. Copper nitride (Cu3N) is a metastable semiconductor with a solar-relevant bandgap that has been reported to exhibit bipolar doping behavior. However, deeper understanding and better control of the mechanism behind this behavior in Cu3N is currently lacking in the literature. In this work, we use combinatorial growth with a temperature gradient to demonstrate both conduction types of phase-pure, sputter-deposited Cu3N thin films...
May 14, 2016: Journal of Applied Physics
https://www.readbyqxmd.com/read/27734666/self-host-blue-emitting-iridium-dendrimer-containing-bipolar-dendrons-for-nondoped-electrophosphorescent-devices-with-superior-high-brightness-performance
#20
Yang Wang, Yaoming Lu, Baoxiang Gao, Shumeng Wang, Junqiao Ding, Lixiang Wang, Xiabin Jing, Fosong Wang
A novel self-host blue-emitting iridium dendrimer, namely B-CzPO, has been designed and synthesized via a post-dendronization route, where a bipolar carbazole/triphenylphosphine oxide hybrid is selected as the peripheral dendron instead of the p-type oligocarbazole used in the unipolar analogue B-CzG2. This structural modification can render B-CzPO with more balanced charge transportation relative to B-CzG2. As a result of the significantly reduced efficiency roll-off, the nondoped phosphorescent organic light-emitting diodes (PhOLEDs) of B-CzPO show a superior high-brightness performance, revealing a luminous efficiency of 21...
October 13, 2016: ACS Applied Materials & Interfaces
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