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https://www.readbyqxmd.com/read/29346606/characteristics-of-cases-with-repeated-sexually-transmitted-infections-massachusetts-2014-2016
#1
Katherine K Hsu, Lauren E Molotnikov, Kathleen A Roosevelt, Heather R Elder, R Monina Klevens, Alfred DeMaria, Sevgi O Aral
Background: Persons with prior sexually transmitted infections (STIs) are at high risk for re-infection. No recent studies have examined the frequency with which persons within a geographic area are diagnosed and reported with multiple bacterial STIs over time. Methods: We conducted a retrospective, population-based study of confirmed syphilis, gonorrhea, and chlamydial infections reported to the Massachusetts state surveillance system within a two-year period, July 28, 2014 - July 27, 2016...
January 13, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29344740/trends-in-awareness-and-use-of-hiv-prep-among-gay-bisexual-and-other-men-who-have-sex-with-men-in-vancouver-canada-2012-2016
#2
Terrance Mosley, Moliehi Khaketla, Heather L Armstrong, Zishan Cui, Paul Sereda, Nathan J Lachowsky, Mark W Hull, Gbolahan Olarewaju, Jody Jollimore, Joshua Edward, Julio S G Montaner, Robert S Hogg, Eric A Roth, David M Moore
Gay, bisexual, and other men who have sex with men (gbMSM) are at the highest risk for HIV infection in British Columbia (BC). Pre-exposure prophylaxis (PrEP) has been recently licensed but is currently not publicly funded in BC. Using respondent-driven sampling, we recruited a cohort of gbMSM to complete a computer-assisted self-interview with follow-up every 6 months. Stratified by HIV status, we examined trends in awareness of PrEP from 11/2012 to 02/2016 and factors associated with PrEP awareness. 732 participants responded to the PrEP awareness question...
January 17, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29344317/survey-of-dermatologists-and-venereologists-shows-varying-approach-to-penile-biopsies
#3
Aaron Wernham, Tang Ngee Shim
OBJECTIVE: To determine frequency of use and safety of epinephrine containing local anesthesia among dermatologists in the United Kingdom and venereologists undertaking penile biopsy. DESIGN: A survey was distributed nationally to members of the British Association of Dermatologists and the British Association for Sexual Health and Human Immunodeficiency Virus in December 2016. RESULTS: Sixty-six responses were received: 36.4 percent of respondents used epinephrine routinely, 16.7 percent sometimes used it, and 47 percent did not use it at all...
October 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/29337847/hiv-care-continuum-disparities-among-bisexual-black-men-and-the-mediating-effect-of-psychosocial-co-morbidities
#4
M Reuel Friedman, Jordan M Sang, Leigh A Bukowski, Derrick D Matthews, Lisa A Eaton, H Fisher Raymond, Ron Stall
INTRODUCTION: Differences across the HIV care continuum between men who have sex with men and women (MSMW) and men who have sex with men only (MSMO) are emerging in recent literature but have not been comprehensively documented among Black MSM. Although MSMW have lower HIV prevalence than MSMO, they are more likely to be HIV-positive unaware and be virally unsuppressed. Explanatory factors for these differences have not previously been assessed. METHODS: Between 2014-2016, we surveyed sexually active Black MSM ≥18 years old at Black Gay Pride events in six U...
January 15, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29334886/factors-associated-with-recent-unsuppressed-viral-load-in-hiv-1-infected-patients-in-care-on-first-line-antiretroviral-therapy-in-south-africa
#5
D Joseph Davey, Z Abrahams, M Feinberg, M Prins, C Serrao, B Medeossi, E Darkoh
Unsuppressed viral load (VL) in patients on antiretroviral therapy (ART) occurs when treatment fails to suppress a person's VL and is associated with decreased survival and increased HIV transmission. The objective of this study was to evaluate factors associated with unsuppressed VL (VL > 400 copies/ml) in patients currently in care on first-line ART for ≥ 6 months attending South African public healthcare facilities. We analysed electronic medical records of ART patients with a VL result on record who started ART between January 2004 and April 2016 from 271 public health facilities...
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29334885/2016-united-kingdom-national-guideline-on-the-sexual-health-care-of-men-who-have-sex-with-men
#6
Dan Clutterbuck, David Asboe, Tristan Barber, Carol Emerson, Nigel Field, Stuart Gibson, Gwenda Hughes, Rachael Jones, Martin Murchie, Achyuta V Nori, Michael Rayment, Ann Sullivan
This guideline is intended for use in UK Genitourinary medicine clinics and sexual health services but is likely to be of relevance in all sexual health settings, including general practice and Contraception and Sexual Health (CASH) services, where men who have sex with men (MSM) seek sexual health care or where addressing the sexual health needs of MSM may have public health benefits. For the purposes of this document, MSM includes all gay, bisexual and all other males who have sex with other males and both cis and trans men...
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29334231/social-capital-and-ptsd-among-plwha-in-china-the-mediating-role-of-resilience-and-internalized-stigma
#7
Mengting Gao, Chenchang Xiao, Xuan Zhang, Shiyue Li, Hong Yan
Post-traumatic Stress Disorder (PTSD) is frequent among people living with HIV/AIDS (PLWHA). Few studies have investigated social-psychological predictors of PTSD in China. This study aimed to examine relationships between social capital, stigma, resilience and PTSD among PLWHA in China, and to provide effective suggestions for PTSD intervention. A cross-sectional study of 520 PLWHA was conducted from November 2015 to January 2016. Survey data were collected using anonymous self-reported questionnaire. Multivariable analyses were used to examine related factors of PTSD, and causal mediation analyses were conducted to assess whether stigma and resilience were mediators...
January 15, 2018: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/29333016/clinicopathological-features-and-outcomes-in-primary-central-nervous-system-lymphoma-a-10-year-experience
#8
Chaitanya Krishna Puligundla, Stalin Bala, Ashok Kumar Karnam, Sadashivudu Gundeti, Tara Roshni Paul, Megha S Uppin, Lakshmi Srinivas Maddali
Context: Primary central nervous system lymphoma (PCNSL) is a variant of extranodal lymphoma, accounting for 4% of primary central nervous system tumors. PCNSL was more common in immunocompetent individuals. International Extranodal Lymphoma Study Group (IELSG) scoring was used for prognostication. High-dose methotrexate regimens along with radiotherapy improved outcomes in PCNSL. Aims: The aim of this study is to analyze the clinical and pathological features, progression-free survival (PFS), and overall survival (OS) in patients with PCNSL...
October 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29331504/a-systematic-review-of-health-care-provider-perceived-barriers-and-facilitators-to-routine-hiv-testing-in-primary-care-settings-in-the-southeastern-united-states
#9
Kelly Tan, Beth Perry Black
Despite efforts to improve HIV screening and testing, many primary care settings do not follow established guidelines. The purpose of our systematic review was to describe health care providers' perceived barriers and facilitators to testing for HIV at poorly used/novel testing sites in the southeastern United States. PubMed, CINAHL, and Embase databases were searched for peer-reviewed studies of providers' perceived barriers and facilitators to routine HIV testing from January 2016 to April 2017 according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement...
December 27, 2017: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/29329280/status-of-hiv-epidemic-control-among-adolescent-girls-and-young-women-aged-15-24-years-seven-african-countries-2015-2017
#10
Kristin Brown, Daniel B Williams, Steve Kinchen, Suzue Saito, Elizabeth Radin, Hetal Patel, Andrea Low, Stephen Delgado, Owen Mugurungi, Godfrey Musuka, Beth A Tippett Barr, E Amaka Nwankwo-Igomu, Leala Ruangtragool, Avi J Hakim, Thokozani Kalua, Rose Nyirenda, Gertrude Chipungu, Andrew Auld, Evelyn Kim, Danielle Payne, Nellie Wadonda-Kabondo, Christine West, Elizabeth Brennan, Beth Deutsch, Anteneh Worku, Sasi Jonnalagadda, Lloyd B Mulenga, Kumbutso Dzekedzeke, Danielle T Barradas, Haotian Cai, Sundeep Gupta, Stanley Kamocha, Margaret A Riggs, Karampreet Sachathep, Wilford Kirungi, Joshua Musinguzi, Alex Opio, Sam Biraro, Elizabeth Bancroft, Jennifer Galbraith, Herbert Kiyingi, Mansoor Farahani, Wolfgang Hladik, Edith Nyangoma, Choice Ginindza, Zandile Masangane, Fortune Mhlanga, Zandile Mnisi, Pasipamire Munyaradzi, Amos Zwane, Sean Burke, Felix B Kayigamba, Harriet Nuwagaba-Biribonwoha, Ruben Sahabo, Trong T Ao, Chiara Draghi, Caroline Ryan, Neena M Philip, Fausta Mosha, Aroldia Mulokozi, Phausta Ntigiti, Angela A Ramadhani, Geoffrey R Somi, Cecilia Makafu, Veronicah Mugisha, Julius Zelothe, Kayla Lavilla, David W Lowrance, Rennatus Mdodo, Elizabeth Gummerson, Paul Stupp, Kyaw Thin, Koen Frederix, Stefania Davia, Amee M Schwitters, Stephen D McCracken, Yen T Duong, David Hoos, Bharat Parekh, Jessica E Justman, Andrew C Voetsch
In 2016, an estimated 1.5 million females aged 15-24 years were living with human immunodeficiency virus (HIV) infection in Eastern and Southern Africa, where the prevalence of HIV infection among adolescent girls and young women (3.4%) is more than double that for males in the same age range (1.6%) (1). Progress was assessed toward the Joint United Nations Programme on HIV/AIDS (UNAIDS) 2020 targets for adolescent girls and young women in sub-Saharan Africa (90% of those with HIV infection aware of their status, 90% of HIV-infected persons aware of their status on antiretroviral treatment [ART], and 90% of those on treatment virally suppressed [HIV viral load <1,000 HIV RNA copies/mL]) (2) using data from recent Population-based HIV Impact Assessment (PHIA) surveys in seven countries...
January 12, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29328508/serologic-responses-and-effectiveness-of-hepatitis-a-vaccination-among-hiv-positive-individuals-during-the-outbreak-of-acute-hepatitis-a
#11
Kuan-Yin Lin, Szu-Min Hsieh, Hsin-Yun Sun, Yi-Chun Lo, Wang-Huei Sheng, Yu-Chung Chuang, Aristine Cheng, Sung-Ching Pan, Guan-Jhou Chen, Chien-Ching Hung, Shan-Chwen Chang
Outbreaks of hepatitis A virus (HAV) infection have been occurring among men who have sex with men (MSM) in Asia-Pacific region, the United States, and several European countries since June 2015, and recently among persons who are homeless and use illicit drugs in the US. We evaluated the serologic responses and effectiveness of HAV vaccination in HIV-positive individuals during the outbreak in Taiwan. From June 1, 2015 to September 30, 2016, anti-HAV IgG was prospectively determined among all HIV-positive individuals...
January 12, 2018: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29327442/transplantation-or-rurality-migration-and-hiv-risk-among-chinese-men-who-have-sex-with-men-in-the-urban-areas
#12
Chuncheng Liu, Rong Fu, Weiming Tang, Bolin Cao, Stephen W Pan, Chongyi Wei, Joseph D Tucker, M Kumi Smith
INTRODUCTION: Migration of men who have sex with men (MSM) from rural to urban areas is common across low- and middle-income countries and is widely believed to contribute to elevated HIV risk among migrant MSM in urban areas. Little consensus exists on whether their risk is due to their transplantation or their being from resource-constrained rural areas. This study seeks to clarify the relationship between migration and HIV risks by comparing differences in HIV-related risky sexual behaviours and healthcare utilization across competing conceptualizations of migratory statuses...
January 2018: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29326409/-life-experiences-of-uninfected-women-living-with-hiv-infected-husbands-a-phenomenological-study
#13
Myoung Hee Seo, Seok Hee Jeong
PURPOSE: This study aimed to understand the meaning and essence of the life experiences of uninfected women living with HIV-infected husbands. METHODS: This qualitative study adopted van Manen's hermeneutic phenomenological method. Study participants were 8 females whose husband had been diagnosed with HIV for longer than 6 months, who had known about their husband's infection for more than 6 months, who were in a legal or common-law marriage and were living with their husbands at the time of interview for this study, and whose HIV antibody test results were negative...
December 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/29326373/hepatitis-a-infections-in-men-who-have-sex-with-men-using-hiv-prep-in-paris
#14
Pauline Penot, Marie-Alice Colombier, Sarah Maylin, Jean-Michel Molina
The current hepatitis A outbreak in Europe is largely involving men having sex with multiple male partners. The objective of the present report was to warn teams dealing against the persistent risk of viral and bacterial sexually transmitted infection (STIs) in patients receiving HIV pre-exposure prophylaxis (PrEP). We have notified and investigated three cases of acute hepatitis A virus (HAV) infection in people receiving HIV PrEP in our clinic between December 2016 and March 2017. The patients were not epidemiologically related, had no recent travel history to HAV endemic areas, reported multiple STIs during this period and had not been vaccinated against HAV...
January 11, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29324811/scale-up-of-kenya-s-national-hiv-viral-load-program-findings-and-lessons-learned
#15
Matilu Mwau, Catherine Akinyi Syeunda, Maureen Adhiambo, Priska Bwana, Lucy Kithinji, Joy Mwende, Laura Oyiengo, Martin Sirengo, Caroline E Boeke
OBJECTIVES: Kenya is one of the first African countries to scale up a national HIV viral load monitoring program. We sought to assess program scale up using the national database and identify areas for systems strengthening. METHODS: Data from January 2012 to March 2016 were extracted from Kenya's national viral load database. Characteristics of 1,108,356 tests were assessed over time, including reason for testing, turnaround times, test results, treatment regimens, and socio-demographic information...
2018: PloS One
https://www.readbyqxmd.com/read/29324463/fractures-related-to-tenofovir-a-case-noncase-study-in-the-european-pharmacovigilance-database
#16
Montserrat G García, Unai Larrinaga-Torrontegui, Eduardo Eduardo Martinez, Unax Lertxundi, Itziar Palacios-Zabalza, Carmelo Aguirre
BACKGROUND: There is no clear consensus on the relationship between tenofovir (TDF) and fracture risk because the studies published so far present contradictory findings. STUDY QUESTION: Our objective was to detect, from the European pharmacovigilance database (EudraVigilance), a signal of fracture risk during TDF exposure in patients infected with HIV. METHODS: Herein, we analyze all the cases of fractures suspected to be related to TDF recorded in EudraVigilance between 2001 and November 10, 2016...
January 8, 2018: American Journal of Therapeutics
https://www.readbyqxmd.com/read/29323108/clinical-study-of-tuberculosis-in-the-head-and-neck-region-11-years-experience-and-a-review-of-the-literature
#17
Pai Pang, Weiyi Duan, Shuchun Liu, Shuang Bai, Yanan Ma, Ruiwu Li, Fayu Liu, Changfu Sun
Tuberculosis (TB) is an infectious disease and major health concern. Head and neck tuberculosis (HNTB) is relatively rare, but can arise in many regions, including the lymph nodes, larynx, oral cavity and pharynx. We retrospectively reviewed the clinical records of 60 patients diagnosed with HNTB in our department between March 2005 and January 2016. A review and summary of previous HNTB articles published in PubMed since 1885 was also performed. The subjects consisted of 17 males and 43 females, and the average age of patients was 45 ± 14...
January 10, 2018: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/29322867/implementing-voluntary-medical-male-circumcision-using-an-innovative-integrated-health-systems-approach-experiences-from-21-districts-in-zimbabwe
#18
Caryl Feldacker, Batsirai Makunike-Chikwinya, Marrianne Holec, Aaron F Bochner, Abby Stepaniak, Robert Nyanga, Sinokuthemba Xaba, Peter H Kilmarx, Amy Herman-Roloff, Taurayi Tafuma, Mufuta Tshimanga, Vuyelwa T Sidile-Chitimbire, Scott Barnhart
BACKGROUND: Despite increased support for voluntary medical male circumcision (VMMC) to reduce HIV incidence, current VMMC progress falls short. Slow progress in VMMC expansion may be partially attributed to emphasis on vertical (stand-alone) over more integrated implementation models that are more responsive to local needs. In 2013, the ZAZIC consortium began implementation of a 5-year, integrated VMMC program jointly with Ministry of Health and Child Care (MoHCC) in Zimbabwe. OBJECTIVE: To explore ZAZIC's approach emphasizing existing healthcare workers and infrastructure, increasing program sustainability and resilience...
2018: Global Health Action
https://www.readbyqxmd.com/read/29322398/hepatitis-c-virus-infection-and-development-of-type-2-diabetes-mellitus-systematic-review-and-meta-analysis-of-the-literature
#19
REVIEW
Silvia Fabiani, Poupak Fallahi, Silvia Martina Ferrari, Mario Miccoli, Alessandro Antonelli
Type 2 diabetes mellitus (T2DM) is an endocrine disorder encompassing multifactorial mechanisms, and chronic hepatitis C virus infection (CHC) is a multifaceted disorder, associated with extrahepatic manifestations, including endocrinological disorders. CHC and T2DM are associated, but the subject remains controversial. We performed a systematic review and meta-analysis evaluating such association, searching on PubMed until February 29, 2016. Inclusion criteria were: 1) presence of at least one internal control group age- and gender-matched (non-hepatopathic controls; and/or hepatopathic, not HCV-positive, controls); 2) sufficient data to calculate odds ratio and relative risk...
January 11, 2018: Reviews in Endocrine & Metabolic Disorders
https://www.readbyqxmd.com/read/29321222/multiple-inhibitory-factors-act-in-the-late-phase-of-hiv-1-replication-a-systematic-review-of-the-literature
#20
REVIEW
Jean-François Gélinas, Deborah R Gill, Stephen C Hyde
The use of lentiviral vectors for therapeutic purposes has shown promising results in clinical trials. The ability to produce a clinical-grade vector at high yields remains a critical issue. One possible obstacle could be cellular factors known to inhibit human immunodeficiency virus (HIV). To date, five HIV restriction factors have been identified, although it is likely that more factors are involved in the complex HIV-cell interaction. Inhibitory factors that have an adverse effect but do not abolish virus production are much less well described...
March 2018: Microbiology and Molecular Biology Reviews: MMBR
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