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https://www.readbyqxmd.com/read/28636297/-supportive-care-in-oncology-a-real-change-for-patients
#1
Alex Friedlaender, Samuel Blaser, Christophe Luthy, Angela Pugliesi Rinaldi
With the increased incidence of cancers due to an aging population, and a prolonged survival thanks to advances in cancer treatments, new therapeutic challenges have arisen. The management of symptoms, the tolerance of increasingly effective oncologic treatments and, finally, quality of life are central concerns of patients and their loved ones. Supportive care in oncology has helped meet these challenges, offering a holistic approach, encompassing somatic, psychiatric and social aid. Inaugurated in 2005, the oncologic supportive care unit of the Geneva University Hospitals allows many cancer patients access to a team of multidisciplinary care-givers to help meet their needs...
May 17, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28635149/underuse-of-risk-assessment-and-overuse-of-ctpa-in-patients-with-suspected-pulmonary-thromboembolism
#2
Michael Perera, Leena Aggarwal, Ian A Scott, Nicholas Cocks
INTRODUCTION: Evidence suggests potential overuse of computerised tomography pulmonary angiography (CTPA) in patients with suspected pulmonary thromboembolism (PTE) in the absence of consistent use of pre-test clinical prediction rules and D-dimer assays. METHODS: 344 consecutive patients undergoing CTPA at a tertiary hospital were studied for use of D-dimer assays and clinical prediction rules for PTE. For each patient, a modified Wells score (mWS), revised Geneva score (rGS) and PISA model were calculated retrospectively; performance characteristics for each rule for PTE were determined in reference to results of CTPA...
June 21, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28632009/self-observation-and-peer-feedback-as-a-faculty-development-approach-for-problem-based-learning-tutors-a-program-evaluation
#3
Irène Garcia, Richard W James, Paul Bischof, Anne Baroffio
PROBLEM: Good teaching requires spontaneous, immediate, and appropriate action in response to various situations. It is even more crucial in problem-based learning (PBL) tutorials, as the tutors, while directing students toward the identification and attainment of learning objectives, must stimulate them to contribute to the process and provide them with constructive feedback. PBL tutors in medicine lack opportunities to receive feedback from their peers on their teaching strategies. Moreover, as tutorials provide little or no time to stop and think, more could be learned by reflecting on the experience than from the experience itself...
March 2, 2017: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/28627851/zika-virus-practical-guidelines
#4
Gilles Eperon, Manuel Schibler, Noémie Wagner, François Chappuis, Isabelle Eperon
Zika virus suddenly emerged in Latin America in 2015‑2016. Congenital malformations have been observed in infected pregnant women, causing a major public health impact in affected countries, particularly in Brazil. In addition, sexual transmission of Zika virus has been well documented. This led to the development of prevention strategies and recommendations for travellers visiting at risk countries. These documents are regularly amended depending on the evolution of scientific knowledge, the epidemiologic trends and the national and international guidelines...
May 3, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28627843/using-the-headsss-guide-to-teach-students-diagnostic-skills-in-adolescent-health-views-from-students-participating-in-interprofessional-courses
#5
Vanessa Parisi, Léo Meyer De Stadelhofen, Benoit Péchère, Sylvain Steimer, Aude De Watteville, Dagmar M Haller, Carol Navarro, Murielle Szynalski-Morel, Anne Meynard
Over the past few years, an interprofessional team of lecturers in Geneva has developed courses entitled « adolescent health and development ». These courses are open to students in medicine, nursing and nutrition, as well as to other interested health professionals. Using vignettes, students who participated in the courses present their thoughts on the use of the HEADSSS interview guide in the diagnostic approach with adolescents. These optional courses provide an opportunity to explore infrequently taught domains of the curriculum in a creative way...
May 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28622983/the-effect-of-a-comprehensive-care-transition-model-on-cost-and-utilization-for-medically-complex-children-with-cerebral-palsy
#6
Steven W Howard, Zidong Zhang, Paula Buchanan, Eric Armbrecht, Christine Williams, Geneva Wilson, Janna Hutchinson, Lindsey Pearson, Samantha Ellsworth, Caitlin M Byler, Travis Loux, Jing Wang, Steph Bernell, Nicholas Holekamp
INTRODUCTION: Our aim was to evaluate cost and acute care utilization related to an organized approach to care coordination and transitional care after major acute care hospitalization for children with medical complexities, including cerebral palsy. METHODS: A retrospective cohort of 32 patients from Ranken Jordan Pediatric Bridge Hospital (RJPBH) who received the Care Beyond the Bedside model was compared with 151 patients receiving standard care elsewhere across Missouri...
June 13, 2017: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/28616163/a-genomic-assessment-of-species-boundaries-and-hybridization-in-a-group-of-highly-polymorphic-anoles-distichus-species-complex
#7
Daniel J MacGuigan, Anthony J Geneva, Richard E Glor
Delimiting young species is one of the great challenges of systematic biology, particularly when the species in question exhibit little morphological divergence. Anolis distichus, a trunk anole with more than a dozen subspecies that are defined primarily by dewlap color, may actually represent several independent evolutionary lineages. To test this, we utilized amplified fragment length polymorphisms (AFLP) genome scans and genetic clustering analyses in conjunction with a coalescent-based species delimitation method...
June 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28605723/a-combined-cognitive-and-gait-quantification-to-identify-normal-pressure-hydrocephalus-from-its-mimics-the-geneva-s-protocol
#8
Gilles Allali, Magali Laidet, Stéphane Armand, Shahan Momjian, Bruno Marques, Arnaud Saj, Frédéric Assal
OBJECTIVES: Idiopathic normal pressure hydrocephalus (iNPH) is very prevalent in aging, underdiagnosed, and represents a rare cause of reversible neurological condition. The clinical triad of iNPH - gait, cognitive and urinary symptoms - and its neuroradiological features (i.e. ventriculomegaly) are not specific and found a various neurodegenerative and/or vascular conditions. We present our iNPH standardized protocol at the Geneva University Hospitals involving a multispecialty team of behavioral neurologists, neurosurgeons, neuropsychologists, engineers, and physical therapists...
June 6, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28602435/one-vs-2-stage-bursectomy-for-septic-olecranon-and-prepatellar-bursitis-a-prospective-randomized-trial
#9
Ilker Uçkay, Elodie von Dach, Cédric Perez, Americo Agostinho, Philippe Garnerin, Benjamin A Lipsky, Pierre Hoffmeyer, Didier Pittet
OBJECTIVE: To assess the optimal surgical approach and costs for patients hospitalized with septic bursitis. PATIENTS AND METHODS: From May 1, 2011, through December 24, 2014, hospitalized patients with septic bursitis at University of Geneva Hospitals were randomized (1:1) to receive 1- vs 2-stage bursectomy. All the patients received postsurgical oral antibiotic drug therapy for 7 days. RESULTS: Of 164 enrolled patients, 130 had bursitis of the elbow and 34 of the patella...
June 8, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28596180/the-non-combatant-status-importance-and-implications-for-medical-personnel
#10
EDITORIAL
Daniel Wilkins, C Dieppe
Under the laws of armed conflict military medics are deemed non-combatants, and as such are subject to certain protections and limitations. The non-combatant status is defined in the famous Geneva Conventions, which form the basis of the international law of armed conflict. The protections afforded to medical personnel in armed conflict are a result of the need to protect and treat the sick and injured during times of hostility. This paper describes the history and legal development of the non-combatant status, and summarises the importance and implications of the contents of the Geneva Conventions that are relevant to medical personnel as non-combatants...
June 8, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/28592598/twenty-year-trends-in-dietary-patterns-in-french-speaking-switzerland-toward-healthier-eating
#11
Pedro Marques-Vidal, Jean-Michel Gaspoz, Jean-Marc Theler, Idris Guessous
Background: Dietary patterns provide a summary of dietary intake, but to our knowledge, few studies have assessed trends in dietary patterns in the population.Objective: The aim was to assess 20-y trends in dietary patterns in a representative sample of the Geneva, Switzerland, population with the consideration of age, sex, education, and generation.Design: Repeated, independent cross-sectional studies were conducted between 1993 and 2014. Dietary intake was assessed by using a validated food-frequency questionnaire...
June 7, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28589772/report-from-european-association-for-the-study-of-the-liver-hcc-summit-geneva-switzerland-2-5-february-2017
#12
Rodolfo Sacco, Aurora Mirabile, Luca Giacomelli, Giampaolo Bresci, Simona Attardo, Giuseppe Cabibbo
The European Association for the Study of the Liver Hepatocellular Carcinoma (HCC) international meeting held in Geneva in February 2017 focused on the state of the art of HCC management, from diagnosis to treatment and the potential development of clinical research in this field. This report reviews some of the most interesting topics discussed at the meeting such as the role of hepatitis C viral infection treatment with direct-acting antivirals in enhancing HCC risk, current prognostic systems, early diagnosis techniques, curative therapies for early HCC and the systemic treatments for advanced disease with a look into future perspectives...
June 7, 2017: Future Oncology
https://www.readbyqxmd.com/read/28579300/correcting-a-fundamental-flaw-in-the-paradigm-for-antimicrobial-susceptibility-testing
#13
Selvi C Ersoy, Douglas M Heithoff, Lucien Barnes, Geneva K Tripp, John K House, Jamey D Marth, Jeffrey W Smith, Michael J Mahan
The emergence and prevalence of antibiotic-resistant bacteria are an increasing cause of death worldwide, resulting in a global 'call to action' to avoid receding into an era lacking effective antibiotics. Despite the urgency, the healthcare industry still relies on a single in vitro bioassay to determine antibiotic efficacy. This assay fails to incorporate environmental factors normally present during host-pathogen interactions in vivo that significantly impact antibiotic efficacy. Here we report that standard antimicrobial susceptibility testing (AST) failed to detect antibiotics that are in fact effective in vivo; and frequently identified antibiotics that were instead ineffective as further confirmed in mouse models of infection and sepsis...
May 29, 2017: EBioMedicine
https://www.readbyqxmd.com/read/28574672/safety-of-multidetector-computed-tomography-pulmonary-angiography-to-exclude-pulmonary-embolism-in-patients-with-a-likely-pretest-clinical-probability
#14
Helia Robert-Ebadi, Frédéric Glauser, Benjamin Planquette, Thomas Moumneh, Grégoire Le Gal, Marc Righini
BACKGROUND: In patients with suspected pulmonary embolism (PE) classified as having a likely or high pre-test clinical probability, the necessity of performing additional testing after a negative multidetector computed tomography pulmonary angiography (CTPA) remains a matter of debate. OBJECTIVES: The aim of this study was to assess the safety of excluding PE by CTPA without additional imaging in patients with a likely pre-test probability of PE. PATIENTS/METHODS: We retrospectively analysed patients included in two multicentre management outcome studies that assessed diagnostic algorithms for PE diagnosis...
June 2, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28558877/mhealth-for-mental-health-in-the-middle-east-need-technology-use-and-readiness-among-palestinians-in-the-west-bank
#15
Dror Ben-Zeev, Cherie Fathy, Geneva Jonathan, Batoul Abuharb, Rachel M Brian, Lana Kesbeh, Samer Abdelkader
Palestinians in the West Bank are at heightened risk for mental health problems. Limited availability of clinicians and a host of geopolitical, topographical, and infrastructural challenges create significant regional barriers to clinic-based care. The objective of this study was to examine whether mHealth approaches that leverage mobile phones for remote mental health treatment may be viable alternatives. We surveyed 272 Palestinian adults in urban, rural, and refugee camp settings. Most participants (93.4%) reported owning mobile phones...
June 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28557861/heartmate-3-in-lowest-intermacs-profile-cohort-the-swiss-experience
#16
Piergiorgio Tozzi, Carlo Banfi, Kameran Ahmadov, Roger Hullin, Philippe Meyer, Raphael Giraud, Lucas Liaudet, Fabrizio Gronchi, Christophe Huber, Matthias Kirsch
New generation devices for long-term mechanical circulatory support are centrifugal pumps having fully magnetically levitated rotors to reduce blood trauma. Recently, the novel HeartMate 3 was cleared for clinical application in Switzerland. In two Swiss University Hospitals part of the "Lausanne-Geneva Transplantation Network," 10 consecutive patients in end-stage heart failure received the HeartMate 3. Device implantation criteria were persistent low output syndrome despite optimal medical treatment. The primary end-point of the study was survival or transplantation to 90 days on the device...
May 23, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28549460/learning-to-use-electronic-health-records-can-we-stay-patient-centered-a-pre-post-intervention-study-with-family-medicine-residents
#17
Cédric Lanier, Melissa Dominicé Dao, Patricia Hudelson, Bernard Cerutti, Noëlle Junod Perron
BACKGROUND: The Electronic Health Record (EHR) is now widely used in clinical encounters. Because its use can negatively impact the physician-patient relationship, several recommendations on the "patient-centered" use of the EHR have been published. However, the impact of training to improve EHR use during clinical encounters is not well known. The aim of this study was to assess the impact of training on residents' EHR-related communication skills and explore whether they varied according to the content of the consultation...
May 26, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28548642/barriers-to-cervical-cancer-screening-in-geneva-depist-study-erratum
#18
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28539590/abcc2-is-associated-with-bacillus-thuringiensis-cry1ac-toxin-oligomerization-and-membrane-insertion-in-diamondback-moth
#19
Josue Ocelotl, Jorge Sánchez, Isabel Gómez, Bruce E Tabashnik, Alejandra Bravo, Mario Soberón
Cry1A insecticidal toxins bind sequentially to different larval gut proteins facilitating oligomerization, membrane insertion and pore formation. Cry1Ac interaction with cadherin triggers oligomerization. However, a mutation in an ABC transporter gene (ABCC2) is linked to Cry1Ac resistance in Plutella xylostella. Cry1AcMod, engineered to lack helix α-1, was able to form oligomers without cadherinbinding and effectively countered Cry1Ac resistance linked to ABCC2. Here we analyzed Cry1Ac and Cry1AcMod binding and oligomerization by western blots using brush border membrane vesicles (BBMV) from a strain of P...
May 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28536303/implementing-a-fee-for-service-cervical-cancer-screening-and-treatment-program-in-cameroon-challenges-and-opportunities
#20
Geneva DeGregorio, Simon Manga, Edith Kiyang, Florence Manjuh, Leslie Bradford, Preetam Cholli, Richard Wamai, Rebecca Ogembo, Zacharie Sando, Yuxin Liu, Lisa Kennedy Sheldon, Kathleen Nulah, Thomas Welty, Edith Welty, Javier Gordon Ogembo
BACKGROUND: Cervical cancer screening is one of the most effective cancer prevention strategies, but most women in Africa have never been screened. In 2007, the Cameroon Baptist Convention Health Services, a large faith-based health care system in Cameroon, initiated the Women's Health Program (WHP) to address this disparity. The WHP provides fee-for-service cervical cancer screening using visual inspection with acetic acid enhanced by digital cervicography (VIA-DC), prioritizing care for women living with HIV/AIDS...
May 23, 2017: Oncologist
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