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https://www.readbyqxmd.com/read/29140858/computerized-cognitive-testing-in-primary-care-a-qualitative-study
#1
Geneva Millett, Gary Naglie, Ross Upshur, Liisa Jaakkimainen, Jocelyn Charles, Mary C Tierney
Computerized cognitive assessment tools may facilitate early identification of dementia in the primary care setting. We investigated primary care physicians' (PCPs') views on advantages and disadvantages of computerized testing based on their experience with the Computer Assessment of Mild Cognitive Impairment (CAMCI). Over a 2-month period, 259 patients, 65 years and older, from the family practice of 13 PCPs completed the CAMCI. Twelve PCPs participated in an individual interview. Generally, PCPs felt that the relationship between them and their patients helped facilitate cognitive testing; however, they thought available paper tests were time consuming and not sufficiently informative...
November 14, 2017: Alzheimer Disease and Associated Disorders
https://www.readbyqxmd.com/read/29117321/the-international-glossary-on-infertility-and-fertility-care-2017
#2
Fernando Zegers-Hochschild, G David Adamson, Silke Dyer, Catherine Racowsky, Jacques de Mouzon, Rebecca Sokol, Laura Rienzi, Arne Sunde, Lone Schmidt, Ian D Cooke, Joe Leigh Simpson, Sheryl van der Poel
STUDY QUESTION: Can a consensus and evidence-driven set of terms and definitions be generated to be used globally in order to ensure consistency when reporting on infertility issues and fertility care interventions, as well as to harmonize communication among the medical and scientific communities, policy-makers, and lay public including individuals and couples experiencing fertility problems? SUMMARY ANSWER: A set of 283 consensus-based and evidence-driven terminologies used in infertility and fertility care has been generated through an inclusive consensus-based process with multiple stakeholders...
September 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29116325/age-and-early-revision-after-primary-total-hip-arthroplasty-for-osteoarthritis
#3
Zachary Meyer, Geneva Baca, Richard Rames, Robert Barrack, John Clohisy, Denis Nam
Prior reports have noted an increased risk of early revision among younger patients undergoing total hip arthroplasty (THA) but have been confounded by the inclusion of various diagnoses. The purpose of this study was to assess the revision rate and the time to revision for patients undergoing THA for osteoarthritis based on age. Patients with a diagnosis of osteoarthritis who underwent both primary and revision THA at the same institution were identified. The time between primary and revision surgery and the indication for revision were collected...
November 1, 2017: Orthopedics
https://www.readbyqxmd.com/read/29115994/exploring-venlafaxine-pharmacokinetic-variability-with-a-phenotyping-approach-a-multicentric-french-swiss-study-marvel-study
#4
Célia Lloret-Linares, Youssef Daali, Sylvie Chevret, Isabelle Nieto, Fanny Molière, Philippe Courtet, Florence Galtier, Raphaëlle-Marie Richieri, Sophie Morange, Pierre-Michel Llorca, Wissam El-Hage, Thomas Desmidt, Frédéric Haesebaert, Philippe Vignaud, Jerôme Holtzmann, Jean-Luc Cracowski, Marion Leboyer, Antoine Yrondi, Fabienne Calvas, Liova Yon, Philippe Le Corvoisier, Olivier Doumy, Kyle Heron, Damien Montange, Siamak Davani, Julien Déglon, Marie Besson, Jules Desmeules, Emmanuel Haffen, Frank Bellivier
BACKGROUND: It is well known that the standard doses of a given drug may not have equivalent effects in all patients. To date, the management of depression remains mainly empirical and often poorly evaluated. The development of a personalized medicine in psychiatry may reduce treatment failure, intolerance or resistance, and hence the burden and costs of mood depressive disorders. The Geneva Cocktail Phenotypic approach presents several advantages including the "in vivo" measure of different cytochromes and transporter P-gp activities, their simultaneous determination in a single test, avoiding the influence of variability over time on phenotyping results, the administration of low dose substrates, a limited sampling strategy with an analytical method developed on DBS analysis...
November 7, 2017: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29115865/the-role-of-meaning-in-life-in-community-dwelling-older-adults-with-depression-and-relationship-to-other-risk-factors
#5
Jana Volkert, Martin Härter, Maria Christina Dehoust, Berta Ausín, Alessandra Canuto, Chiara Da Ronch, Anna Suling, Luigi Grassi, Manuel Munoz, Ana Belén Santos-Olmo, Susanne Sehner, Kerstin Weber, Karl Wegscheider, Hans-Ulrich Wittchen, Holger Schulz, Sylke Andreas
OBJECTIVES: The aims of this study were to examine the association of Meaning in Life (MiL) with sociodemographic and physical factors, and its association with depression in older people. METHOD: A cross-sectional survey with a sample of N = 2104 older adults from communities of four European countries was conducted, using an age-appropriate interview for the diagnosis of depression and the Schedule for Meaning in Life Evaluation (SMiLE) questionnaire to assess MiL...
November 8, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/29107949/user-perception-of-endocervical-sampling-a-randomized-comparison-of-endocervical-evaluation-with-the-curette-vs-cytobrush
#6
Manuela Undurraga, Rosa Catarino, Isabelle Navarria, Yasmine Ibrahim, Evelyne Puget, Isabelle Royannez Drevard, Jean-Claude Pache, Jean-Christophe Tille, Patrick Petignat
OBJECTIVES: To evaluate whether the endocervical brush (ECB) is better accepted by patients and health care providers for endocervical evaluation when compared to the endocervical curette (ECC), without a decrease in the quality of sampling. METHODS: Two hundred patients with cervical dysplasia were randomized at the colposcopy clinic of the University Hospital of Geneva into two groups according to technique. Patients and physicians' preference regarding the technique as well as the quality of samples were assessed...
2017: PloS One
https://www.readbyqxmd.com/read/29094934/universal-dynamics-of-molecular-reorientation-in-hybrid-lead-iodide-perovskites
#7
Douglas H Fabini, Ting Ann Siaw, Constantinos C Stoumpos, Geneva Laurita, Daniel Olds, Katharine Page, Jerry G Hu, Mercouri G Kanatzidis, Songi Han, Ram Seshadri
The role of organic molecular cations in the high-performance perovskite photovoltaic absorbers, methylammonium lead iodide (MAPbI3) and formamidinium lead iodide (FAPbI3), has been an enigmatic subject of great interest. Beyond aiding in the ease of processing of thin films for photovoltaic devices, there have been suggestions that many of the remarkable properties of the halide perovskites can be attributed to the dipolar nature and the dynamic behavior of these cations. Here, we establish the dynamics of the molecular cations in FAPbI3 between 4 K and 340 K and the nature of their interaction with the surrounding inorganic cage using a combination of solid state nuclear magnetic resonance and dielectric spectroscopies, neutron scattering, calorimetry, and ab initio calculations...
November 2, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29080550/frequency-of-use-and-acceptability-of-clinical-prediction-rules-for-pulmonary-embolism-among-swiss-general-internal-medicine-residents
#8
N Faller, O Stalder, A Limacher, S Bassetti, J H Beer, D Genné, E Battegay, D Hayoz, J Leuppi, B Mueller, A Perrier, G Waeber, N Rodondi, D Aujesky
INTRODUCTION: Whether clinical prediction rules for pulmonary embolism are accepted and used among general internal medicine residents remains uncertain. We therefore evaluated the frequency of use and acceptability of the Revised Geneva Score (RGS) and the Pulmonary Embolism Severity Index (PESI), and explored which factors were associated with rule use. MATERIALS/METHODS: In an online survey among general internal medicine residents from 10 Swiss hospitals, we assessed rule acceptability using the Ottawa Acceptability of Decision Rules Instrument (OADRI) and explored the association between physician and training-related factors and rule use using mixed logistic regression models...
October 18, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/29068444/structural-convergence-properties-of-amorphous-ingazno4-from-simulated-liquid-quench-methods
#9
Jacob C Buchanan, Dylan B Fast, Benjamin E Hanken, Thomas J L Mustard, Geneva Laurita, Tsung-Han Chiang, Douglas A Keszler, Mas A Subramanian, John F Wager, Michelle R Dolgos, James R Rustad, Paul Ha-Yeon Cheong
The study of structural properties of amorphous structures is complicated by the lack of long-range order and necessitates the use of both cutting-edge computer modeling and experimental techniques. With regards to the computer modeling, many questions on convergence arise when trying to assess the accuracy of a simulated system. What cell size maximizes the accuracy while remaining computationally efficient? More importantly, does averaging multiple smaller cells adequately describe features found in bulk amorphous materials? How small is too small? The aims of this work are: (1) to report a newly developed set of pair potentials for InGaZnO4 and (2) to explore the effects of structural parameters such as simulation cell size and numbers on the structural convergence of amorphous InGaZnO4...
November 14, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29065028/a-multilevel-analysis-of-professional-conflicts-in-health-care-teams-insight-for-future-training
#10
Naike Bochatay, Nadia M Bajwa, Stéphane Cullati, Virginie Muller-Juge, Katherine S Blondon, Noëlle Junod Perron, Fabienne Maître, Pierre Chopard, Nu Viet Vu, Sara Kim, Georges L Savoldelli, Patricia Hudelson, Mathieu R Nendaz
PURPOSE: Without a proper understanding of conflict between health care professionals, designing effective conflict management training programs for trainees that reflect the complexity of the clinical working environment is difficult. To better inform the development of conflict management training, this study sought to explore health care professionals' experiences of conflicts and their characteristics. METHOD: Between 2014 and early 2016, 82 semistructured interviews were conducted with health care professionals directly involved in first-line patient care in four departments of the University Hospitals of Geneva...
November 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29062392/jurisdiction-of-the-medical-ethics-committees
#11
Božidar Voljč
Ethical principles of assessing medical research are to the greatest extent defined by the Nuremberg Code, the Declarations of Geneva and Helsinki, and the Oviedo Convention. Pursuant to their directives various national Medical Ethics Committees (MECs) were established which assess the ethics of research according to the risk and benefit ratio of the persons involved. Following the example of other countries, medical ethics committees eventually appeared also in hospitals and some medical and educational institutions around Slovenia...
October 2017: Zdravstveno Varstvo
https://www.readbyqxmd.com/read/29049507/the-revised-declaration-of-geneva-a-modern-day-physician-s-pledge
#12
Ramin Walter Parsa-Parsi
No abstract text is available yet for this article.
October 14, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29047469/mirages-at-lake-geneva-the-fata-morgana
#13
Andrew T Young, Eric Frappa
Fata Morgana mirages are frequently seen at Lake Geneva. We show the first photographs of them, including a real-time video, and explain their main features, which are due to the very turbulent entrainment zones of capping inversions, especially in valley circulations.
July 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/29038941/spatial-and-temporal-heavy-metal-distribution-and-surface-water-characterization-of-kanjli-wetland-a-ramsar-site-india-using-different-indices
#14
Navdeep Singh, Manpreet Kaur, Jatinder Kaur Katnoria
Suitability of surface water of Kanjli wetland, Punjab (India) during the period of 2013-2015 was assessed for drinking, irrigation and aquatic life using a water quality index (WQI), heavy metal pollution index (HPI) and aquatic toxicity index (ATI). WQI was calculated using 14 physico-chemical parameters while HPI determination used nine heavy metals like As, Cd, Co, Cr, Cu, Fe, Mn, Pb and Zn. WQI revealed that Kanjli wetland contained medium quality water (irrigation and aquatic life). Cr, Cd and Co exceeded desirable limits of World Health Organization (WHO, Guidelines for drinking-water quality, World Health Organization, Geneva, 2011) and Indian drinking water standard (2012) during all the three seasons (monsoon, post monsoon and winter)...
October 16, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/29038835/interaction-between-lrp5-and-periostin-gene-polymorphisms-on-serum-periostin-levels-and-cortical-bone-microstructure
#15
J Pepe, N Bonnet, F R Herrmann, E Biver, R Rizzoli, T Chevalley, S L Ferrari
We investigated the interaction between periostin SNPs and the SNPs of the genes assumed to modulate serum periostin levels and bone microstructure in a cohort of postmenopausal women. We identified an interaction between LRP5 SNP rs648438 and periostin SNP rs9547970 on serum periostin levels and on radial cortical porosity. PURPOSE: The purpose of this study is to investigate the interaction between periostin gene polymorphisms (SNPs) and other genes potentially responsible for modulating serum periostin levels and bone microstructure in a cohort of postmenopausal women...
October 16, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/29024621/is-atypical-swallowing-associated-with-relapse-in-orthognathic-patients-a-retrospective-study-of-256-patients
#16
Jean-Marc Foletti, Gregory S Antonarakis, Camille Galant, Delphine S Courvoisier, Paolo Scolozzi
PURPOSE: To determine the association of atypical swallowing (AS) with relapse in patients undergoing combined orthodontic and orthognathic treatment. MATERIALS AND METHODS: In this retrospective cohort study, the clinical data of all patients who underwent combined surgical and orthodontic treatment from 1998 through 2015 at the University Hospital of Geneva (Geneva, Switzerland) were reviewed. The primary outcome variables were 1) AS and 2) post-treatment relapse...
September 15, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28989600/chemical-tuning-of-dynamic-cation-off-centering-in-the-cubic-phases-of-hybrid-tin-and-lead-halide-perovskites
#17
Geneva Laurita, Douglas H Fabini, Constantinos C Stoumpos, Mercouri G Kanatzidis, Ram Seshadri
Hybrid halide perovskites combine ease of preparation and relatively abundant constituent elements with fascinating photophysical properties. Descriptions of the chemical and structural drivers of the remarkable properties have often focused on the potential role of the dynamic order/disorder of the molecular A-site cations. We reveal here a key aspect of the inorganic framework that potentially impacts the electronic, thermal, and dielectric properties. The temperature evolution of the X-ray pair distribution functions of hybrid perovskites ABX3 [A(+) = CH3NH3 (MA) or CH(NH2)2 (FA); B(2+) = Sn or Pb; X(-) = Br, or I] in their cubic phases above 300 K reveals temperature-activated displacement (off-centering) of the divalent group 14 cations from their nominal, centered sites...
August 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28986035/estimating-the-full-public-health-value-of-vaccination
#18
Bradford D Gessner, David Kaslow, Jacques Louis, Kathleen Neuzil, Katherine L O'Brien, Valentina Picot, Tikki Pang, Umesh D Parashar, Mitra Saadatian-Elahi, Christopher B Nelson
There is an enhanced focus on considering the full public health value (FPHV) of vaccination when setting priorities, making regulatory decisions and establishing implementation policy for public health activities. Historically, a therapeutic paradigm has been applied to the evaluation of prophylactic vaccines and focuses on an individual benefit-risk assessment in prospective and individually-randomized phase III trials to assess safety and efficacy against etiologically-confirmed clinical outcomes. By contrast, a public health paradigm considers the population impact and encompasses measures of community benefits against a range of outcomes...
October 3, 2017: Vaccine
https://www.readbyqxmd.com/read/28976585/usutu-virus-in-cerebrospinal-fluid-a-two-year-survey-in-a-tertiary-care-hospital-geneva-switzerland
#19
S Cordey, G Vieille, L Turin, L Kaiser
In 2009, the Usutu virus (USUV) was first reported as a cause of human neuroinvasive disorders. In Switzerland, USUV has been detected in wild birds with a seroprevalence of up to 6.59% in captive specimens sampled from zoo enclosures. This study investigates the clinical prevalence of USUV in human acute neuroinvasive disorders in Switzerland. Two hundred fifty-eight cerebrospinal fluid samples collected between 2015 and 2017 for routine clinical care in a tertiary level hospital (Geneva) were tested for USUV by rRT-PCR...
October 4, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28961564/70th-world-health-assembly-geneva-switzerland
#20
Wayne W Morriss, Julian Gore-Booth
No abstract text is available yet for this article.
September 28, 2017: Anesthesia and Analgesia
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