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https://www.readbyqxmd.com/read/28209349/frequency-of-and-significance-of-physical-frailty-in-patients-with-heart-failure
#1
Quin E Denfeld, Kerri Winters-Stone, James O Mudd, Shirin O Hiatt, Christopher V Chien, Christopher S Lee
Physical frailty is an important prognostic indicator in heart failure (HF); however, few studies have examined the relation between physical frailty and invasive hemodynamics among adults with HF. The purpose of this study was to characterize physical frailty in HF in relation to invasive hemodynamics. We enrolled 49 patients with New York Heart Association class II to IV HF when participants were scheduled for a right-sided cardiac heart catheterization procedure. Physical frailty was measured according to the "frailty phenotype": shrinking, weakness, slowness, physical exhaustion, and low physical activity...
January 25, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28202384/implementing-take-home-naloxone-in-an-urban-community-pharmacy
#2
Joshua L Akers, Ryan N Hansen, Ryan D Oftebro
OBJECTIVE: Morbidity and mortality associated with opioid use have increased across the nation, growing into what can only be described as an epidemic. SETTING: In Washington State between 2002 and 2004, the statewide death rate attributed to any opioid was 6.6 per 100,000 people, but between 2011 and 2013 it increased to 8.6 per 100,000 people. Pharmacies provide a unique access point for harm reduction services to patients due to their ease of accessibility in the community...
February 12, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28202043/reliability-and-validity-of-the-korean-version-of-the-coronary-revascularization-outcome-questionnaire
#3
Minju Kim, JiYeong Seo, Jin-Yong Hwang, Ki Soo Park
BACKGROUND: People with ischemic heart disease have increased drastically, and their health-related quality of life (HRQOL) has been increasingly important. The Coronary Revascularization Outcome Questionnaire (CROQ) is a widely used tool to assess the quality of life in patients with coronary artery disease. The purpose of this study was to rigorously examine the psychometric properties of the CROQ in patients who had undergone percutaneous coronary intervention (PCI). METHODS: The CROQ was translated into Korean...
February 15, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28196479/treatment-completion-for-latent-tuberculosis-infection-a-retrospective-cohort-study-comparing-9%C3%A2-months-of-isoniazid-4%C3%A2-months-of-rifampin-and-3%C3%A2-months-of-isoniazid-and-rifapentine
#4
Adelaide H McClintock, McKenna Eastment, Christy M McKinney, Caroline L Pitney, Masahiro Narita, David R Park, Shireesha Dhanireddy, Alexandra Molnar
BACKGROUND: The U.S. Centers for Disease Control and Prevention (CDC) recommended a new regimen for treatment of latent tuberculosis (three months of weekly isoniazid and rifapentine) in late 2011. While completion rates of this regimen were reported to be higher than nine months of isoniazid, little is known about the completion rates of three months of isoniazid and rifapentine compared to nine months of isoniazid or four months of rifampin in actual use scenarios. METHODS: We conducted a retrospective cohort study comparing treatment completion for latent tuberculosis (TB) infection in patients treated with nine months of isoniazid, three months of isoniazid and rifapentine or four months of rifampin in outpatient clinics and a public health TB clinic in Seattle, Washington...
February 14, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28195846/color-doppler-ultrasound-assessment-of-activity-in-keloids
#5
Nelson Lobos, Ximena Wortsman, Fernando Valenzuela, Faustino Alonso
BACKGROUND: The assessment of activity in keloids may be critical for defining their management. There is a lack of clinical scorings designed for the evaluation of keloids and biopsies may be contraindicated. OBJECTIVE: To assess the sonographic activity of keloids in comparison with clinical scoring. MATERIALS AND METHODS: A retrospective study of the clinical and color Doppler ultrasound (CDU) images of patients medically derived to CDU with the diagnosis of keloid was performed...
February 9, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28193509/pilot-study-analyzing-automated-ecg-screening-of-hypertrophic-cardiomyopathy
#6
Matthew Campbell, Xuefu Zhou, Chia Han, Hedayat Abrishami, Gregory Webster, Christina Y Miyake, Christopher T Sower, Jeffery B Anderson, Timothy K Knilans, Richard J Czosek
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is one of the leading causes of sudden cardiac death in athletes. However, pre-participation ECG screening has often been criticized for failing to meet cost-effectiveness thresholds, in part because of high false-positive rates and the cost of ECG screening itself. OBJECTIVES: To assess the testing characteristics of an automated ECG algorithm designed to screen for HCM in a multi-institutional pediatric cohort. METHODS: ECGs from patients with HCM aged 12 - 20 years from 3 pediatric institutions were screened for ECG criteria for HCM using a previously described automated computer algorithm developed specifically for HCM ECG screening...
February 10, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28192764/adolescent-depressive-symptoms-in-india-australia-and-usa-exploratory-structural-equation-modelling-of-cross-national-invariance-and-predictions-by-gender-and-age
#7
Andrew J Lewis, Bosco Rowland, Aiden Tran, Renatti F Solomon, George C Patton, Richard F Catalano, John W Toumbourou
BACKGROUND: The present study compares depressive symptoms in adolescents from three countries: Mumbai, India; Seattle, United States; and Melbourne, Australia measured using the Short Moods and Feelings Questionnaire (SMFQ). The study cross nationally compares SMFQ depressive symptom responses by age and gender. METHODS: Data from a cross-nationally matched survey were used to compare factorial and measurement characteristics from samples of students from Grade 7 and 9 in Mumbai, India (n=3268) with the equivalent cohorts in the Washington State, USA (n=1907) and Victoria, Australia (n=1900)...
January 21, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28182863/randomized-controlled-trial-of-a-community-health-worker-self-management-support-intervention-among-low-income-adults-with-diabetes-seattle-washington-2010-2014
#8
Karin Nelson, Leslie Taylor, Julie Silverman, Meghan Kiefer, Paul Hebert, Dan Lessler, James Krieger
INTRODUCTION: Community health workers (CHWs) can improve diabetes outcomes; however, questions remain about translating research findings into practical low-intensity models for safety-net providers. We tested the effectiveness of a home-based low-intensity CHW intervention for improving health outcomes among low-income adults with diabetes. METHODS: Low-income patients with glycated hemoglobin A1c (HbA1c) of 8.0% or higher in the 12 months before enrollment from 3 safety-net providers were randomized to a 12-month CHW-delivered diabetes self-management intervention or usual care...
February 9, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28181955/minutes-of-the-business-meeting-of-the-international-society-of-gynecological-pathologists-isgyp-seattle-13th-march-2016
#9
Esther Oliva, W Glenn McCluggage
No abstract text is available yet for this article.
March 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28181210/the-differences-in-ecgs-interpretation-in-top-level-athletes
#10
Agnieszka A Jakubiak, Krystyna Burkhard-Jagodzińska, Wojciech Król, Marcin Konopka, Dominik Bursa, Dariusz Sitkowski, Marek Kuch, Wojciech Braksator
BACKGROUND: The Ministry of Health in Poland recommends ECG- based cardiovascular screening in athletes, but so far, there is lack of guidelines on preparticipation assessment. We compared different criteria of ECG screening assessment in the group of top-level athletes. AIMS: The aims were to evaluate the prevalence of ECG changes in athletes that necessitate further cardiological work-up according to three criteria in various age groups as well as to identify factors determining the occurrence of changes related and unrelated to the training...
February 9, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28177301/tracking-short-term-biodistribution-and-long-term-clearance-of-spio-tracers-in-magnetic-particle-imaging
#11
Paul Keselman, Elaine Yu, Xinyi Zhou, Patrick Goodwill, Prashant Chandrasekharan, R Matthew Ferguson, Amit Khandhar, Scott Kemp, Kannan Krishnan, Bo Zheng, Steven Conolly
Magnetic Particle Imaging (MPI) is an emerging tracer-based medical imaging modality that images non-radioactive, kidney-safe superparamagnetic iron oxide (SPIO) tracers. MPI offers quantitative, high-contrast and high-SNR images, so MPI has exceptional promise for applications such as cell tracking, angiography, brain perfusion, cancer detection, traumatic brain injury and pulmonary imaging. In assessing MPI's utility for applications mentioned above, it is important to be able to assess tracer short-term biodistribution as well as long-term clearance from the body...
February 8, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28159780/growth-differentiation-factor-15-and-risk-of-ckd-progression
#12
Viji Nair, Cassianne Robinson-Cohen, Michelle R Smith, Keith A Bellovich, Zeenat Yousuf Bhat, Maria Bobadilla, Frank Brosius, Ian H de Boer, Laurent Essioux, Ivan Formentini, Crystal A Gadegbeku, Debbie Gipson, Jennifer Hawkins, Jonathan Himmelfarb, Bryan Kestenbaum, Matthias Kretzler, Maria Chiara Magnone, Kalyani Perumal, Susan Steigerwalt, Wenjun Ju, Nisha Bansal
Growth differentiation factor-15 (GDF-15) is a member of the TGF-β cytokine superfamily that is widely expressed and may be induced in response to tissue injury. Elevations in GDF-15 may identify a novel pathway involved in loss of kidney function among patients with CKD. Among participants in the Clinical Phenotyping and Resource Biobank (C-PROBE) study and the Seattle Kidney Study (SKS), we tested whether kidney tissue expression of GDF15 mRNA correlates with circulating levels of GDF-15 and whether elevations in circulating GDF-15 are associated with decline in kidney function...
February 3, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28159337/normal-computerized-q-wave-measurements-in-healthy-young-athletes
#13
Divakar Saini, Aaron F Grober, David Hadley, Victor Froelicher
BACKGROUND: Recent Expert consensus statements have sought to decrease false positive rates of electrocardiographic abnormalities requiring further evaluation when screening young athletes. These statements are largely based on traditional ECG patterns and have not considered computerized measurements. OBJECTIVE: To define the normal limits for Q wave measurements from the digitally recorded ECGs of healthy young athletes. METHODS: All athletes were categorized by sex and level of participation (high school, college, and professional), and underwent screening ECGs with routine pre-participation physicals, which were electronically captured and analyzed...
January 16, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28153390/nucleolin-staining-may-aid-in-the-identification-of-circulating-prostate-cancer-cells
#14
Heather J Chalfin, James E Verdone, Emma E van der Toom, Stephanie Glavaris, Michael A Gorin, Kenneth J Pienta
INTRODUCTION: Circulating tumor cells (CTCs) have great potential as circulating biomarkers for solid malignancies. Currently available assays for CTC detection rely on epithelial markers with somewhat limited sensitivity and specificity. We found that the staining pattern of nucleolin, a common nucleolar protein in proliferative cells, separates CTCs from white blood cells (WBCs) in men with metastatic prostate cancer. PATIENTS AND METHODS: Whole peripheral blood from 3 men with metastatic prostate cancer was processed with the AccuCyte CTC system (RareCyte, Seattle, WA)...
January 4, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28146269/the-prevalence-and-management-of-angina-among-patients-with-chronic-coronary-artery-disease-across-us-outpatient-cardiology-practices-insights-from-the-angina-prevalence-and-provider-evaluation-of-angina-relief-appear-study
#15
Faraz Kureshi, Ali Shafiq, Suzanne V Arnold, Kensey Gosch, Tracie Breeding, Ashwath S Kumar, Philip G Jones, John A Spertus
Although eliminating angina is a primary goal in treating patients with chronic coronary artery disease (CAD), few contemporary data quantify prevalence and severity of angina across US cardiology practices. The authors hypothesized that angina among outpatients with CAD managed by US cardiologists is low and its prevalence varies by site. Among 25 US outpatient cardiology clinics enrolled in the American College of Cardiology Practice Innovation and Clinical Excellence (PINNACLE) registry, we prospectively recruited a consecutive sample of patients with chronic CAD over a 1- to 2-week period at each site between April 2013 and July 2015, irrespective of the reason for their appointment...
January 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28116229/compliance-with-washington-state-s-requirement-for-residential-carbon-monoxide-alarms
#16
Neil B Hampson, James R Holm
Carbon monoxide (CO) poisoning is responsible for significant morbidity and mortality in the US. In response, a majority of states have passed legislation in recent years requiring the installation of residential CO alarms. There is, however, no published information evaluating compliance with such laws. Employees of a Seattle medical center were surveyed in 2008 regarding home use of CO and smoke alarms. Washington State enacted legislation requiring residential CO alarms by all residences by January 1, 2013...
March 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28115072/complications-of-spinal-cord-injury-over-the-first-year-after-discharge-from-inpatient-rehabilitation
#17
Michael D Stillman, Jason Barber, Steve Burns, Steve Williams, Jeanne M Hoffman
OBJECTIVES: To describe the prevalence and cumulative incidence (CI) of secondary complications of spinal cord injury (SCI) in the first year after discharge from inpatient rehabilitation (IR). To evaluate potential associations between risk of complications and socio-demographic and injury-specific factors. DESIGN: Secondary analysis of data collected for a single-site, single-blind, randomized controlled trial comparing telephone follow up to usual care. SETTING: Two inpatient rehabilitation units comprising the Northwest Regional SCI System in Seattle, Washington...
January 20, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28107317/photography-in-telemedicine-improving-diagnosis-of-chronic-graft-versus-host-disease
#18
Brianna Busby, Shannon Campbell, Rachel Cole, Charisse DeVries, Kamille Dobbins, Mary Beth Trimble, Mihkaila Wickline
BACKGROUND: The long-term follow-up (LTFU) team at the Seattle Cancer Care Alliance uses telemedicine to diagnose and treat post-transplantation complications in hematopoietic cell transplantation (HCT) survivors. Photos are often requested via the telemedicine service to aid in diagnosis, but they are typically of poor quality, making them unusable. OBJECTIVES: This project offered bachelor of science in nursing students, partnered with a comprehensive cancer center, the opportunity to participate in an evidence-based practice project to improve detection and management of chronic graft-versus-host disease (cGVHD) in patients after HCT...
1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28103621/development-and-validation-of-a-training-module-on-the-use-of-acetic-acid-for-the-detection-of-barrett-s-neoplasia
#19
Fergus J Q Chedgy, Kesavan Kandiah, Hugh Barr, John De Caestecker, Simon Dwerryhouse, Balint Eross, Charles Gordon, Susi Green, Andy Li, James Brown, Gaius Longcroft-Wheaton, Pradeep Bhandari
Background and study aims Acetic acid chromoendoscopy (AAC) enhances the ability to correctly identify Barrett's neoplasia, and is increasingly used by both expert and nonexpert endoscopists. Despite its increasing use, there is no validated training strategy to achieve competence. The aims of our study were to develop a validated training tool in AAC-assisted lesion recognition, to assess endoscopists' baseline knowledge of AAC-assisted lesion recognition, and to evaluate the efficacy and impact of this training tool...
February 2017: Endoscopy
https://www.readbyqxmd.com/read/28102875/prevalence-of-abnormal-electrocardiograms-in-swiss-elite-athletes-detected-with-modern-screening-criteria
#20
Tilman Perrin, Lukas Daniel Trachsel, Simon Schneiter, Andrea Menafoglio, Silvia Albrecht, Tony Pirrello, Prisca Eser, Laurent Roten, Boris Gojanovic, Matthias Wilhelm
AIMS OF THE STUDY: Sudden cardiac arrest in athletes is a rare but dramatic event. The value of a routine electrocardiogram (ECG) during preparticipation screening (PPS) remains controversial, partly because of the relatively high number of false positive findings. Our study aimed to evaluate the prevalence of abnormal ECGs in consecutive Swiss elite athletes, overall and with regard to different sports classes, using modern screening criteria. METHODS: We analysed the 12-lead resting ECGs of high-level elite athletes (age ≥14 years) recorded at the Swiss Olympic Medical Centre Magglingen between 2013 and 2016 during routine PPS...
January 19, 2017: Swiss Medical Weekly
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