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https://www.readbyqxmd.com/read/29214319/electrocardiographic-findings-in-national-basketball-association-athletes
#1
Marc P Waase, R Kannan Mutharasan, William Whang, Marco R DiTullio, John P DiFiori, Lisa Callahan, Jimmie Mancell, Dermot Phelan, Allan Schwartz, Shunichi Homma, David J Engel
Importance: While it is known that long-term intensive athletic training is associated with cardiac structural changes that can be reflected on surface electrocardiograms (ECGs), there is a paucity of sport-specific ECG data. This study seeks to clarify the applicability of existing athlete ECG interpretation criteria to elite basketball players, an athlete group shown to develop significant athletic cardiac remodeling. Objective: To generate normative ECG data for National Basketball Association (NBA) athletes and to assess the accuracy of athlete ECG interpretation criteria in this population...
December 6, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29212372/crowdsourcing-evaluation-of-ureteroscopic-videos-using-the-post-ureteroscopic-lesion-scale-puls-to-assess-ureteral-injury
#2
Kamaljot S Kaler, Zachary A Valley, Khiera C Bettir, Shoaib Safiullah, Daniel J Lama, Renai Yoon, Jaime Landman, Ralph Clayman
INTRODUCTION AND OBJECTIVES: We hypothesized that crowdsourcing assessments could be applied to the Post-Ureteroscopic Lesion Scale (PULS) for ureteral injury. METHODS: At a single institution, we prospectively digitally recorded 14 ureters at the terminal portion of standard ureteroscopic procedures. Each recording was reviewed by 10 global experts to determine a mean PULS score. Following training, the Crowd-Sourced Assessment of Technical Skills, C-SATS® (CSATS, Inc...
December 7, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29209208/the-clinical-pharmacokinetics-and-pharmacodynamics-of-warfarin-when-combined-with-compound-danshen-a-case-study-for-combined-treatment-of-coronary-heart-diseases-with-atrial-fibrillation
#3
Chunxiao Lv, Changxiao Liu, Zhuhua Yao, Xiumei Gao, Lanjun Sun, Jia Liu, Haibo Song, Ziqiang Li, Xi Du, Jinxia Sun, Yanfen Li, Kui Ye, Ruihua Wang, Yuhong Huang
Warfarin is used as anticoagulant and Compound Danshen prescription (CDP) is able to promote blood circulation. The combination might produce a synergic effect for patients of coronary heart diseases (CHDs) with atrial fibrillation (AF). Whether the combination increases the bleeding risk of warfarin is unclear, so the effects of Compound Danshen dripping pill (CDDP) on the pharmacokinetics (PK) and pharmacodynamics (PD) profiles of warfarin was investigated in patients. The dose and blood concentrations of warfarin, the four indicators of blood coagulation, prothrombin time, activated partial thromboplatin time, thrombin time, fibrinogen, and international normalized ratio value were compared when with and without CDDP treatment...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29205345/evidence-based-medicine-and-state-health-care-coverage-the-washington-health-technology-assessment-program
#4
David J Rothman, Kristy L Blackwood, Whitney Adair, Sheila M Rothman
OBJECTIVE: To evaluate the Washington State Health Technology Assessment Program (WHTAP). STUDY SETTING: Washington State Health Technology Assessment Program proceedings in Seattle, Washington. DATA COLLECTION AND STUDY DESIGN: We assessed the program through observation of its proceedings over a 5-year period, 2009-2014. We conducted detailed analyses of the documents it produced and reviewed relevant literature. PRINCIPAL FINDINGS: Washington State Health Technology Assessment Program is unique compared to other state and federal programs...
December 3, 2017: Health Services Research
https://www.readbyqxmd.com/read/29197395/translation-and-psychometric-testing-of-the-farsi-version-of-the-seattle-angina-questionnaire
#5
Zahra Taheri-Kharameh, Majideh Heravi-Karimooi, Nahid Rejeh, Ebrahim Hajizadeh, Mojtaba Vaismoradi, Sherrill Snelgrove, Ali Montazeri
BACKGROUND: Angina pectoris causes substantial psychological and functional disabilities and adversely effects quality of life in patients. The aim of this study was to investigate the psychometric properties including validity and reliability of the Farsi version of the Seattle angina questionnaire. METHODS: The 'forward-backward' procedure was applied to translate this questionnaire from English to Farsi. The translated version of the Seattle angina questionnaire was assessed in terms of validity and reliability with a convenience sample of 200 patients suffering from angina pectoris who were recruited from the inpatient ward (post CCU) and outpatient department at two teaching hospitals in an urban area of Iran...
December 2, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29192004/effectiveness-of-a-comprehensive-case-management-service-for-children-with-medical-complexity
#6
Tamara D Simon, Kathryn B Whitlock, Wren Haaland, Davene R Wright, Chuan Zhou, John Neff, Waylon Howard, Brian Cartin, Rita Mangione-Smith
OBJECTIVES: To assess whether children with medical complexity (CMC) exposed to a hospital-based comprehensive case management service (CCMS) experience improved health care quality, improved functional status, reduced hospital-based utilization, and/or reduced overall health care costs. METHODS: Eligible CMC at Seattle Children's Hospital were enrolled in a cluster randomized controlled trial between December 1, 2010, and September 29, 2014. Participating primary care providers (PCPs) were randomly assigned, and CMC either had access to an outpatient hospital-based CCMS or usual care directed by their PCP...
November 30, 2017: Pediatrics
https://www.readbyqxmd.com/read/29189603/the-dynamics-of-stress-and-fatigue-across-menopause-attractors-coupling-and-resilience
#7
Lisa Taylor-Swanson, Alexander E Wong, David Pincus, Jonathan E Butner, Jennifer Hahn-Holbrook, Mary Koithan, Kathryn Wann, Nancy F Woods
OBJECTIVE: The objective of this study was to evaluate the regulatory dynamics between stress and fatigue experienced by women during the menopausal transition (MT) and early postmenopause (EPM). Fatigue and perceived stress are commonly experienced by women during the MT and EPM. We sought to discover relationships between these symptoms and to employ these symptoms as possible markers for resilience. METHODS: Participants were drawn from the longitudinal Seattle Midlife Women's Health Study...
November 20, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29180344/behavioral-interventions-to-prevent-or-delay-dementia-protocol-for-a-randomized-comparative-effectiveness-study
#8
Glenn Smith, Melanie Chandler, Dona Ec Locke, Julie Fields, Vaishali Phatak, Julia Crook, Sherrie Hanna, Angela Lunde, Miranda Morris, Michelle Graff-Radford, Christine A Hughes, Susan Lepore, Andrea Cuc, Maria Caselli, Duane Hurst, Jennifer Wethe, Andrea Francone, Jeanne Eilertsen, Pauline Lucas, Charlene Hoffman Snyder, LeeAnn Kuang, Marigrace Becker, Pamela Dean, Nancy Diehl, Marvin Lofquist, Shirley Vanderhook, Diana Myles, Denise Cochran
BACKGROUND: Currently, people at risk for dementia and their caregivers are confronted with confusing choices about what behavioral interventions are most effective. OBJECTIVE: The objective of this study is to determine which empirically supported behavioral interventions most impact the outcomes highly valued by patients with mild cognitive impairment and their partners. METHODS: This protocol describes a comparative effectiveness trial targeting 300 participants with mild cognitive impairment and their study partners...
November 27, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29175463/increasing-methamphetamine-injection-among-non-msm-who-inject-drugs-in-king-county-washington
#9
Sara Nelson Glick, Richard Burt, Kim Kummer, Joe Tinsley, Caleb J Banta-Green, Matthew R Golden
BACKGROUND: In King County, Washington, the HIV prevalence among men who have sex with men (MSM) who inject methamphetamine is high, while it is low among other people who inject drugs (PWID). Local drug problem indicators suggest that methamphetamine use is increasing. The extent to which this increase affects MSM and non-MSM, and whether MSM and non-MSM networks are connected through injection equipment sharing, is unknown. METHODS: We used data from two serial cross-sectional surveys of PWID including five biannual surveys of Public Health-Seattle and King County Needle and Syringe Exchange Program clients (NSEP, N=2135, 2009-2017) and three National HIV Behavioral Surveillance IDU surveys (NHBS, N=1709, 2009-2015)...
November 16, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29175281/predicting-survival-in-heart-failure-patients-with-an-implantable-cardioverter-defibrillator-the-heart-failure-meta-score
#10
Ana C Alba, Stephen D Walter, Gordon H Guyatt, Wayne C Levy, Jiming Fang, Heather J Ross, Douglas S Lee
BACKGROUND: Prognostic evaluation in heart failure (HF) is important to predict future events and decide timely management. Many HF patients are treated with an implantable cardioverter defibrillator (ICD). This study aimed to validate a meta-analytically-derived prognostic score to predict survival in ICD-HF patients. METHODS AND RESULTS: The HF Meta-Score includes 14 independent mortality predictors identified in a meta-analysis, including age, sex, ethnicity, diabetes, chronic obstructive pulmonary disease, peripheral vascular disease, atrial fibrillation, ischemic cardiomyopathy, history of heart failure admission, NYHA class, left ventricular ejection fraction, renal function, QRS duration, secondary prevention indication and ICD shocks...
November 22, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/29170448/colorectal-cancer-screening-in-patients-with-spinal-cord-injury-yields-similar-results-to-the-general-population-with-an-effective-bowel-preparation-a-retrospective-chart-audit
#11
Brandon J Teng, Shawn H Song, Jelena N Svircev, Jason A Dominitz, Stephen P Burns
STUDY DESIGN: Retrospective chart audit. OBJECTIVES: To compare adequacy of colonoscopy bowel preparation and diagnostic findings between persons with SCI receiving an extended inpatient bowel preparation and the general population. SETTING: Veterans Affairs Puget Sound Healthcare System, Seattle, WA, USA. METHODS: We reviewed an electronic database of all colonoscopies performed at a tertiary Veterans Affairs medical center between 7/12/13 and 15/10/15...
November 24, 2017: Spinal Cord
https://www.readbyqxmd.com/read/29163134/geographic-variations-in-the-incidence-of-glioblastoma-and-prognostic-factors-predictive-of-overall-survival-in-us-adults-from-2004-2013
#12
Hao Xu, Junrui Chen, Hongzhi Xu, Zhiyong Qin
Objective: The purpose of this study was to evaluate variations in the regional incidence of glioblastoma in US adults in 2004-2013. Study Design and Setting: We evaluated 24,262 patients with primary glioblastoma. Data were categorized based on geographic regions that included different SEER registry sites as follows: (1) Northeast: Connecticut, New Jersey (3,977 patients); (2) South: Kentucky, Louisiana, Metropolitan Atlanta, Rural Georgia, Greater Georgia (excluding AT and RG) (5,212 patients); (3) North Central: Metropolitan Detroit, Iowa (2,320 patients); (4) West: Hawaii, New Mexico, Seattle (Puget Sound), Utah, San Francisco-Oakland SMSA, San Jose-Monterey, Los Angeles, Greater California (excluding SF, LA, and SJ), Alaska (12,753 patients)...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29161901/long-term-outcomes-of-the-randomized-controlled-trial-comparing-5-aminolaevulinic-acid-and-photofrin-photodynamic-therapy-for-barrett-s-oesophagus-related-neoplasia
#13
Darina Kohoutova, Rehan Haidry, Matthew Banks, Mohammed Adil Butt, Jason Dunn, Sally Thorpe, Laurence Lovat
OBJECTIVE: Photodynamic therapy (PDT) was used as therapy for early neoplasia associated with Barrett's oesophagus (BE). This is 5-year follow-up of patients enrolled into randomised controlled trial of 5-aminolaevulinic acid (ALA) vs. Photofrin PDT. METHODS: Biopsies were taken from original Barrett's segment during endoscopic follow up using Seattle protocol. Endoscopic mucosal resection (EMR) ± radiofrequency ablation (RFA) was preferred therapy in patients who failed PDT and/or had recurrent neoplasia...
November 21, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29153734/the-incidence-of-second-mesiobuccal-canals-located-in-maxillary-molars-with-the-aid-of-cone-beam-computed-tomography
#14
Ben Studebaker, Lars Hollender, Lloyd Mancl, James D Johnson, Avina Paranjpe
INTRODUCTION: Many endodontic treatment failures in maxillary molars result from missed second mesiobuccal (MB2) canals. An MB2 canal orifice is present in as many as 95% of maxillary molars, but these canals are not always located during endodontic procedures. Additional tools, such as cone-beam computed tomographic (CBCT) imaging, may be needed to locate these canals in maxillary molars. Hence, the aims of this study were to investigate the frequency of use of CBCT imaging during the treatment of maxillary molars and to evaluate the influence of its use on the detection of MB2 canals...
November 15, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29136420/assessment-of-environmental-contamination-with-pathogenic-bacteria-at-a-hospital-laundry-facility
#15
Karen E Michael, David No, William E Daniell, Noah S Seixas, Marilyn C Roberts
Little is known about exposure to pathogenic bacteria among industrial laundry workers who work with soiled clinical linen. To study worker exposures, an assessment of surface contamination was performed at an industrial laundry facility serving hospitals in Seattle, WA, USA. Surface swab samples (n = 240) from the environment were collected during four site visits at 3-month intervals. These samples were cultured for Clostridium difficile, methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant enterococci (VRE)...
November 10, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/29134629/proton-pump-inhibitor-use-and-dementia-risk-prospective-population-based-study
#16
Shelly L Gray, Rod L Walker, Sascha Dublin, Onchee Yu, Erin J Aiello Bowles, Melissa L Anderson, Paul K Crane, Eric B Larson
OBJECTIVES: To determine whether higher cumulative proton pump inhibitor (PPI) exposure is associated with greater dementia risk. DESIGN: Prospective population-based cohort study. SETTING: Kaiser Permanente Washington, an integrated healthcare delivery system in Seattle, Washington. PARTICIPANTS: Individuals aged 65 and older without dementia at study entry (N = 3,484). MEASUREMENTS: Participants were screened for dementia every 2 years, and those who screened positive underwent extensive evaluation...
November 14, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29131825/a-model-based-clustering-method-to-detect-infectious-disease-transmission-outbreaks-from-sequence-variation
#17
Rosemary M McCloskey, Art F Y Poon
Clustering infections by genetic similarity is a popular technique for identifying potential outbreaks of infectious disease, in part because sequences are now routinely collected for clinical management of many infections. A diverse number of nonparametric clustering methods have been developed for this purpose. These methods are generally intuitive, rapid to compute, and readily scale with large data sets. However, we have found that nonparametric clustering methods can be biased towards identifying clusters of diagnosis-where individuals are sampled sooner post-infection-rather than the clusters of rapid transmission that are meant to be potential foci for public health efforts...
November 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/29130439/cochlear-implantation-in-children-with-postlingual-progressive-steeply-sloping-high-frequency-hearing-loss
#18
Margaret A Meredith, Jay T Rubinstein, Kathleen C Y Sie, Susan J Norton
BACKGROUND: Children with steeply sloping sensorineural hearing loss (SNHL) lack access to critical high-frequency cues despite the use of advanced hearing aid technology. In addition, their auditory-only aided speech perception abilities often meet Food and Drug Administration criteria for cochlear implantation. PURPOSE: The objective of this study was to describe hearing preservation and speech perception outcomes in a group of young children with steeply sloping SNHL who received a cochlear implant (CI)...
November 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/29122130/outcomes-of-chronic-total-occlusion-percutaneous-coronary-intervention-in-patients-with-diabetes-insights-from-the-open-cto-registry
#19
Adam C Salisbury, James Sapontis, J Aaron Grantham, Mohammed Qintar, Kensey L Gosch, William Lombardi, Dimitri Karmpaliotis, Jeffrey Moses, David J Cohen, John A Spertus, Mikhail Kosiborod
OBJECTIVES: Few studies have evaluated the relationship of diabetes with technical success and periprocedural complications, and no studies have compared patient-reported health status after chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in patients with and without diabetes. BACKGROUND: CTOs are more common in patients with diabetes, yet CTO PCI is less often attempted in patients with diabetes than in patients without. The association between diabetes and health status after CTO PCI is unknown...
November 13, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29118692/statistical-image-properties-in-large-subsets-of-traditional-art-bad-art-and-abstract-art
#20
Christoph Redies, Anselm Brachmann
Several statistical image properties have been associated with large subsets of traditional visual artworks. Here, we investigate some of these properties in three categories of art that differ in artistic claim and prestige: (1) Traditional art of different cultural origin from established museums and art collections (oil paintings and graphic art of Western provenance, Islamic book illustration and Chinese paintings), (2) Bad Art from two museums that collect contemporary artworks of lesser importance (© Museum Of Bad Art [MOBA], Somerville, and Official Bad Art Museum of Art [OBAMA], Seattle), and (3) twentieth century abstract art of Western provenance from two prestigious museums (Tate Gallery and Kunstsammlung Nordrhein-Westfalen)...
2017: Frontiers in Neuroscience
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