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https://www.readbyqxmd.com/read/27906766/prescription-of-post-exposure-prophylaxis-for-hiv-1-in-the-emergency-room-correct-transmission-risk-assessment-remains-challenging
#1
Alex Marzel, Henriette Heinrich, Lukas Schilliger, Jan S Fehr, Huldrych F Günthard, Roger Kouyos, Silvana K Rampini
BACKGROUND: Limited data are available about the accuracy of PEP prescription in the emergency rooms. Here, we evaluated PEP prescription decision-making with respect to the risk of sexual HIV transmission and the exposed person`s fear vis-à-vis HIV. METHODS: Using a risk-assessment algorithm, we retrospectively evaluated the adequacy of PEP prescription for all persons presenting at the emergency room of the University Hospital Zurich after consensual sex from 2007 to 2013...
November 30, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27894023/persistent-generalized-periodic-discharges-a-specific-marker-of-fatal-outcome-in-cerebral-hypoxia
#2
Roland Renzel, Christian R Baumann, Ian Mothersill, Rositsa Poryazova
OBJECTIVES: Electroencephalography (EEG) is one of the methods used in predicting the outcome after cerebral hypoxia. In this study we aim to evaluate the significance of generalized periodic discharges (GPD) as a prognostic marker. METHODS: We retrospectively analyzed the medical histories of patients, who underwent an EEG after cardiac arrest during the time period from 2005 to 2013 at the University Hospital Zurich. All EEGs were re-interpreted using the 2012 American Clinical Neurophysiology Society (ACNS) classification for intensive care unit (ICU) EEGs...
November 5, 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/27887601/protocol-for-a-prospective-randomized-study-on-neurophysiological-assessment-of-lower-urinary-tract-function-in-a-healthy-cohort
#3
Stéphanie van der Lely, Martina Stefanovic, Melanie R Schmidhalter, Marta Pittavino, Reinhard Furrer, Martina D Liechti, Martin Schubert, Thomas M Kessler, Ulrich Mehnert
BACKGROUND: Lower urinary tract symptoms are highly prevalent and a large proportion of these symptoms are known to be associated with a dysfunction of the afferent pathways. Diagnostic tools for an objective and reproducible assessment of afferent nerve function of the lower urinary tract are missing. Previous studies showed first feasibility results of sensory evoked potential recordings following electrical stimulation of the lower urinary tract in healthy subjects and patients. Nevertheless, a refinement of the methodology is necessary...
November 25, 2016: BMC Urology
https://www.readbyqxmd.com/read/27878843/mixed-method-research-protocol-defining-and-operationalizing-patient-related-complexity-of-nursing-care-in-acute-care-hospitals
#4
Evelyn Huber, Michael Kleinknecht-Dolf, Phil Marianne Müller, Christiane Kugler, Rebecca Spirig
AIM: To define the concept of patient-related complexity of nursing care in acute care hospitals and to operationalize it in a questionnaire. BACKGROUND: The concept of patient-related complexity of nursing care in acute care hospitals has not been conclusively defined in the literature. The operationalization in a corresponding questionnaire is necessary, given the increased significance of the topic, due to shortened lengths of stay and increased patient morbidity...
November 23, 2016: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/27878789/regional-sociocultural-differences-as-important-correlate-of-physical-activity-and-sedentary-behaviour-in-swiss-preschool-children
#5
Claudia S Leeger-Aschmann, Einat A Schmutz, Thomas Radtke, Tanja H Kakebeeke, Annina E Zysset, Nadine Messerli-Bürgy, Kerstin Stülb, Amar Arhab, Andrea H Meyer, Simone Munsch, Oskar G Jenni, Jardena J Puder, Susi Kriemler
QUESTION: Regional differences in physical activity in school-aged children and adults even within one country with the same political and health care system have been observed and could not be explained by sociodemographic or individual variables. We analysed whether such differences were already present in preschool children. METHODS: Swiss children from 84 childcare centres in five cantons (Aargau, Bern, Fribourg, Vaud, Zurich) comprising about 50% of the population of the country participated...
2016: Swiss Medical Weekly
https://www.readbyqxmd.com/read/27876020/the-brief-negative-symptom-scale-validation-of-the-german-translation-and-convergent-validity-with-self-rated-anhedonia-and-observer-rated-apathy
#6
Martin Bischof, Caitriona Obermann, Matthias N Hartmann, Oliver M Hager, Matthias Kirschner, Agne Kluge, Gregory P Strauss, Stefan Kaiser
BACKGROUND: Negative symptoms are considered core symptoms of schizophrenia. The Brief Negative Symptom Scale (BNSS) was developed to measure this symptomatic dimension according to a current consensus definition. The present study examined the psychometric properties of the German version of the BNSS. To expand former findings on convergent validity, we employed the Temporal Experience Pleasure Scale (TEPS), a hedonic self-report that distinguishes between consummatory and anticipatory pleasure...
November 22, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27821377/-vigilance-for-veterinary-medicinal-products-reports-of-adverse-reactions-in-the-year-2015
#7
C Müntener, J Kupper, H Naegeli, B Gassner
A total of 292 adverse reactions to veterinary medicinal products were reported during the year 2015. This represents an increase of 9% compared to the previous year (268 reports). Similar to previous years, most of the reactions reported were linked to the use of antiparasitics (55.1%), non-steroidal anti-inflammatory products (8.9%) or antiinfectives (9.3%). The affected animal species were primarily dogs (198 reports) and cats (42 reports), followed by cattle (31 reports) and horses (8 reports). Additional 42 reports were provided within the frame of consultations with Tox Info Suisse in Zürich and involved mainly the excessive intake of flavored tablets...
November 2016: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/27811381/report-from-iabr-breath-summit-2016-in-zurich-switzerland
#8
J Beauchamp, J Pleil, T Risby, R Dweik
No abstract text is available yet for this article.
November 3, 2016: Journal of Breath Research
https://www.readbyqxmd.com/read/27788450/illicit-drug-use-among-gay-and-bisexual-men-in-44-cities-findings-from-the-european-msm-internet-survey-emis
#9
Axel J Schmidt, Adam Bourne, Peter Weatherburn, David Reid, Ulrich Marcus, Ford Hickson
BACKGROUND: Anecdotal evidence suggests that men who have sex with men (MSM) are increasingly combining sex and illicit drugs (an activity referred to as 'chemsex'), in particular GHB/GBL, ketamine, crystal meth, or mephedrone (here called 4-chems). Use of such drugs has been associated with mental health and sexual health harms. We aim to compare patterns of illicit drug use among MSM in 44 European urban centres. METHODS: In 2010, EMIS recruited 174,209 men from 38 countries to an anonymous online questionnaire in 25 languages...
October 24, 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27788405/rethinking-retention-in-treatment-of-opioid-dependence-the-eye-of-the-beholder
#10
Marc Vogel, Kenneth M Dürsteler, Marc Walter, Marcus Herdener, Carlos Nordt
Opioid dependence often is a chronic relapsing disorder. The evidence for medication-assisted treatment (MAT) being the treatment of first choice is unequivocal. Yet, health systems, professionals and patients often fail to offer or, respectively, to enter long-term and low-threshold MAT and instead treat opioid dependence as a semi-acute disorder. We claim that the typical perspective on treatment retention, one of the pivotal outcomes used for evaluation of MAT, contributes to this phenomenon by obscuring the chronic nature of opioid dependence...
October 24, 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27787705/occurrence-of-the-herbicide-glyphosate-and-its-metabolite-ampa-in-surface-waters-in-switzerland-determined-with-on-line-solid-phase-extraction-lc-ms-ms
#11
Thomas Poiger, Ignaz J Buerge, Astrid Bächli, Markus D Müller, Marianne E Balmer
Glyphosate is currently one of the most important herbicides worldwide. Its unique properties provide for a wide range of uses in agriculture but also in non-agricultural areas. At the same time, its zwitterionic nature prevents the inclusion in multi-residue analytical methods for environmental monitoring. Consequently, despite its extensive use, data on occurrence of glyphosate in the aquatic environment is still scarce. Based on existing methods, we developed a simplified procedure for the determination of glyphosate and its main metabolite aminomethylphosphonic acid (AMPA) in water samples using derivatization with fluorenylmethyl chloroformate FMOC-Cl, combined with on-line solid phase extraction and liquid chromatography-tandem mass spectrometry (LC-MS/MS) detection...
October 27, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27781022/about-atmps-sops-and-gmp-the-hurdles-to-produce-novel-skin-grafts-for-clinical-use
#12
REVIEW
Fabienne Hartmann-Fritsch, Daniela Marino, Ernst Reichmann
BACKGROUND: The treatment of severe full-thickness skin defects represents a significant and common clinical problem worldwide. A bio-engineered autologous skin substitute would significantly reduce the problems observed with today's gold standard. METHODS: Within 15 years of research, the Tissue Biology Research Unit of the University Children's Hospital Zurich has developed autologous tissue-engineered skin grafts based on collagen type I hydrogels. Those products are considered as advanced therapy medicinal products (ATMPs) and are routinely produced for clinical trials in a clean room facility following the guidelines for good manufacturing practice (GMP)...
September 2016: Transfusion Medicine and Hemotherapy
https://www.readbyqxmd.com/read/27779271/inter-and-intra-observer-variability-of-radiography-and-computed-tomography-for-evaluation-of-zurich-cementless-acetabular-cup-placement-ex-vivo
#13
Jessica O Leasure, Jeffrey N Peck, Armando Villamil, Kara L Fiore, Cheryl A Tano
OBJECTIVE: To evaluate the inter- and intra-observer variability in measurement of the angle of lateral opening (ALO) and version angle measurement using digital radiography and computed tomography (CT). METHODS: Each hemipelvis was implanted with a cementless acetabular cup. Ventrodorsal and mediolateral radiographs were made of each pelvis, followed by CT imaging. After removal of the first cup, the pelves were implanted with an acetabular cup in the contralateral acetabulum and imaging was repeated...
October 25, 2016: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/27771626/pregnancy-outcomes-regarding-maternal-serum-afp-value-in-second-trimester-screening
#14
Karolina Bartkute, Dalia Balsyte, Josef Wisser, Juozas Kurmanavicius
AIM: The aim of this study was to evaluate the predictive value of α-fetoprotein in maternal serum (MS-AFP) as a marker for diverse pregnancy outcomes. METHODS: The study was based on pregnancy and delivery data from 5520 women between 1999 and 2014 at University Hospital of Zurich (UHZ). INCLUSION CRITERIA: both MS-AFP and pregnancy outcome were known for the same pregnancy. Pregnancy outcomes and characteristics such as fetal malformation, intrauterine fetal death (IUFD) and intrauterine growth retardation as well as maternal age, weight before pregnancy, gestational age (GA) at delivery, newborn weight, length and head circumference were analyzed with respect to the MS-AFP value...
October 24, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27763671/the-lives-of-mary-foote-painter-and-jungian
#15
Richard Trousdell
Mary Foote (1872-1968) was a successful early twentieth century American artist who suddenly closed her New York studio in 1926 to go to Zurich to study with Jung. There she joined his 'Interpretation of Visions' seminars (1930-1934), which she recorded and edited. This work won Jung's praise and his friendship, but all too often Foote was seen merely as a secretary or background figure. Deirdre Bair's biography of Jung suggested that Foote's life and work deserved fuller study, if only to rebalance our view of Jung's early women followers...
November 2016: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/27757577/automated-determination-of-bone-age-from-hand-x-rays-at-the-end-of-puberty-and-its-applicability-for-age-estimation
#16
Hans Henrik Thodberg, Rick R van Rijn, Oskar G Jenni, David D Martin
The BoneXpert method for automated determination of bone age from hand X-rays was introduced in 2009, covering the Greulich-Pyle bone age ranges up to 17 years for boys and 15 years for girls. This paper presents an extension of the method up to bone age 19 years for boys and 18 years for girls. The extension was developed based on images from the First Zurich Longitudinal Study of 231 healthy children born in 1954-1956 and followed with annual X-rays of both hands until adulthood. The method was validated on two cross-sectional studies of healthy children from Rotterdam and Los Angeles...
October 18, 2016: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/27752453/the-2015-annual-meeting-of-setac-german-language-branch-in-zurich-7-10-september-2015-ecotoxicology-and-environmental-chemistry-from-research-to-application
#17
Inge Werner, Annette Aldrich, Benjamin Becker, Dennis Becker, Markus Brinkmann, Michael Burkhardt, Norbert Caspers, Sophie Campiche, Nathalie Chèvre, Rolf-Alexander Düring, Beate I Escher, Fabian Fischer, Sabrina Giebner, Katharina Heye, Henner Hollert, Marion Junghans, Cornelia Kienle, Katja Knauer, Muris Korkaric, Veronika Märkl, Jane Muncke, Jörg Oehlmann, Georg Reifferscheid, Daniel Rensch, Andreas Schäffer, Sabrina Schiwy, Simon Schwarz, Helmut Segner, Eszter Simon, Rita Triebskorn, Etiënne L M Vermeirssen, Thomas Wintgens, Markus Zennegg
This report provides a brief review of the 20th annual meeting of the German Language Branch of the Society of Environmental Toxicology and Chemistry (SETAC GLB) held from September 7th to 10th 2015 at ETH (Swiss Technical University) in Zurich, Switzerland. The event was chaired by Inge Werner, Director of the Swiss Centre for Applied Ecotoxicology (Ecotox Centre) Eawag-EPFL, and organized by a team from Ecotox Centre, Eawag, Federal Office of the Environment, Federal Office of Agriculture, and Mesocosm GmbH (Germany)...
2016: Environmental Sciences Europe
https://www.readbyqxmd.com/read/27747040/observership-in-china-an-opinion-about-current-and-future-collaboration
#18
Claudio Caviezel
China offers great opportunities for Europe in thoracic surgery training and research. Thoracic surgeons from Europe might profit from intense collaborations and on the other hand provide assist in academic structures, creating guidelines and patient follow-up strategies. With an observership award the AME Publishing Group and the ESTS enable another unique kind of collaboration for thoracic surgery trainees. This year the observership allows a bridge between Zurich in Switzerland and Beijing in China. The current situation of thoracic surgery in Switzerland and the chances of collaboration are discussed in this opinion paper...
September 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27733413/screening-of-gestational-diabetes-mellitus-in-early-pregnancy-by-oral-glucose-tolerance-test-and-glycosylated-fibronectin-study-protocol-for-an-international-prospective-multicentre-cohort-trial
#19
E A Huhn, T Fischer, C S Göbl, M Todesco Bernasconi, M Kreft, M Kunze, A Schoetzau, E Dölzlmüller, W Eppel, P Husslein, N Ochsenbein-Koelble, R Zimmermann, E Bäz, H Prömpeler, E Bruder, S Hahn, I Hoesli
INTRODUCTION: As the accurate diagnosis and treatment of gestational diabetes mellitus (GDM) is of increasing importance; new diagnostic approaches for the assessment of GDM in early pregnancy were recently suggested. We evaluate the diagnostic power of an 'early' oral glucose tolerance test (OGTT) 75 g and glycosylated fibronectin (glyFn) for GDM screening in a normal cohort. METHODS AND ANALYSIS: In a prospective cohort study, 748 singleton pregnancies are recruited in 6 centres in Switzerland, Austria and Germany...
October 12, 2016: BMJ Open
https://www.readbyqxmd.com/read/27707682/detection-of-candidatus-neoehrlichia-mikurensis-and-other-anaplasmataceae-and-rickettsiaceae-in-canidae-in-switzerland-and-mediterranean-countries
#20
R Hofmann-Lehmann, N Wagmann, M L Meli, B Riond, M Novacco, D Joekel, F Gentilini, F Marsilio, M G Pennisi, A Lloret, T Carrapiço, F S Boretti
'Candidatus Neoehrlichia mikurensis' is an emerging tick-borne zoonotic agent that primarily affects immunocompromised human patients. Dogs and foxes are frequently exposed to ticks, and both species are in close proximity to humans. This is the first study to systematically investigate the occurrence of 'Candidatus Neoehrlichia mikurensis' in Canidae in Europa. We analyzed 1'739 blood samples from dogs in Switzerland, Italy, Spain and Portugal and 162 blood samples from free-ranging red foxes (Vulpes vulpes) in Switzerland...
October 2016: Schweizer Archiv Für Tierheilkunde
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