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https://www.readbyqxmd.com/read/29223327/restoration-of-motor-function-after-operative-reconstruction-of-the-acutely-transected-spinal-cord-in-the-canine-model
#1
Zehan Liu, Shuai Ren, Kuang Fu, Qiong Wu, Jun Wu, Liting Hou, Hong Pan, Linlin Sun, Jian Zhang, Bingjian Wang, Qing Miao, Guiyin Sun, Vincenzo Bonicalzi, Sergio Canavero, Xiaoping Ren
BACKGROUND: Cephalosomatic anastomosis or what has been called a "head transplantation" requires full reconnection of the respective transected ends of the spinal cords. The GEMINI spinal cord fusion protocol has been developed for this reason. Here, we report the first randomized, controlled study of the GEMINI protocol in large animals. METHODS: We conducted a randomized, controlled study of a complete transection of the spinal cord at the level of T10 in dogs at Harbin Medical University, Harbin, China...
December 6, 2017: Surgery
https://www.readbyqxmd.com/read/29215506/can-early-patient-reported-outcomes-be-used-to-identify-patients-at-risk-for-poor-1-year-health-outcomes-after-lumbar-laminectomy-with-arthrodesis
#2
Taylor E Purvis, Brian J Neuman, Lee H Riley, Richard L Skolasky
STUDY DESIGN: Prospective cohort. OBJECTIVE: Determine 1) between-patient variability in patient-reported outcomes (PROs) at 4 postoperative time points; 2) within-patient correlation of 1-year PROs with PROs at 3 earlier time points; and 3) ability of early PROs to predict 1-year PROs after lumbar laminectomy with arthrodesis. SUMMARY OF BACKGROUND DATA: It is unclear whether early PROs can help identify patients at risk for poor health outcomes...
December 5, 2017: Spine
https://www.readbyqxmd.com/read/29215492/postoperative-opioid-use-complications-and-costs-in-surgical-management-of-lumbar-spondylolisthesis
#3
Daniel Vail, Tej D Azad, Chloe O'Connell, Summer S Han, Anand Veeravagu, John K Ratliff
STUDY DESIGN: Retrospective analysis on a national longitudinal database (2007-2014). OBJECTIVE: To determine the association between arthrodesis and complication rates, costs, surgical revision, and postoperative opioid prescription. SUMMARY OF BACKGROUND DATA: Arthrodesis in patients receiving laminectomy for lumbar spondylolisthesis remains controversial. However, population-level evidence to support the use of arthrodesis remains limited...
December 5, 2017: Spine
https://www.readbyqxmd.com/read/29211872/misplacement-of-stent-into-epidural-venous-plexus-with-resultant-cauda-equina-syndrome-and-open-surgical-treatment-a-case-report
#4
Benjamin B Whiting, Celene B Mulholland, Lorin Daniels, U Kumar Kakarla, Nicholas Theodore, Laura A Snyder
BACKGROUND AND IMPORTANCE: Endovascular therapy has proven to be a safe, minimally invasive treatment for multiple etiologies, but proper precautions must be taken to avoid complications. When complications occur, they should be promptly identified and corrected when possible. This case report describes endovascular stents misplaced into the epidural spinous venous plexus rather than the iliofemoral arteries, causing cauda equina syndrome, as well as the spinal procedure performed to treat the resulting spinal canal compression...
December 2, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29210720/massive-macroglossia-after-posterior-cranial-fossa-surgery-a-case-report
#5
Jennifer F Ha, Lisa N Vitale, Marie A Pfarr, Yu Kawai, David A Zopf
A 16-year-old boy with Chiari 1 malformation presented for an elective suboccipital craniectomy and C1 laminectomy. His intraoperative course was uneventful. At the conclusion of the procedure, he met extubation criteria and followed commands. After extubation, he developed progressive upper airway obstruction and became obtunded. He was reintubated via videolaryngoscopy, which showed edema not only to the tongue, but also to the posterior pharynx and blisters over the vocal folds and epiglottis. The patient was transferred to the pediatric intensive care unit intubated and sedated...
November 27, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/29206315/intrathecal-trialing-of-continuous-infusion-combination-therapy-with-hydromorphone-and-bupivacaine-in-failed-back-surgery-patients
#6
Ryan J Galica, Salim M Hayek, Elias Veizi, Matthew T McEwan, Sivakanth Katta, Omar Ali, Nida Aziz, Nidhi Sondhi
OBJECTIVES: Intrathecal (IT) trial is a prognostic interventional pain management procedure employed to determine the potential success of treating intractable pain with an implantable infusion device system. There is a dearth of data regarding trials with continuous infusion of combination therapy (e.g. opioid combined with local anesthetic). The objective of the this study was to determine the overall outcomes of continuous infusion IT trials and factors influencing long-term success of IT therapy in patients with chronic intractable pain post-laminectomy...
December 5, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29204734/basic-concepts-in-metal-work-failure-after-metastatic-spine-tumour-surgery
#7
REVIEW
Naresh Kumar, Ravish Patel, Anshuja Charvi Wadhwa, Aravind Kumar, Helena Maria Milavec, Dhiraj Sonawane, Gurpal Singh, Lorin Michael Benneker
PURPOSE: The development of spinal implants marks a watershed in the evolution of metastatic spine tumour surgery (MSTS), which has evolved from standalone decompressive laminectomy to instrumented stabilization and decompression with reconstruction when necessary. Fusion may not be feasible after MSTS due to poor quality of graft host bed along with adjunct chemotherapy and/or radiotherapy postoperatively. With an increase in the survival of patients with spinal tumours, there is a probability of an increase in the rate of implant failure...
December 4, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29201578/vertebral-compression-fractures-after-lumbar-instrumentation
#8
Michelle Granville, Aldo Berti, Robert E Jacobson
Lumbar spinal stenosis (LSS) is primarily found in an older population. This is a similar demographic group that develops both osteoporosis and vertebral compression fractures (VCF). This report reviewed a series of patients treated for VCF that had previous lumbar surgery for symptomatic spinal stenosis. Patients that only underwent laminectomy or fusion without instrumentation had a similar distribution of VCF as the non-surgical population in the mid-thoracic, or lower thoracic and upper lumbar spine. However, in the patients that had previous short-segment spinal instrumentation, fractures were found to be located more commonly in the mid-lumbar spine or sacrum adjacent to or within one or two spinal segments of the spinal instrumentation...
September 29, 2017: Curēus
https://www.readbyqxmd.com/read/29201191/extended-magnetic-resonance-imaging-studies-on-the-effect-of-classically-activated-microglia-transplantation-on-white-matter-regeneration-following-spinal-cord-focal-injury-in-adult-rats
#9
Wiesław Marcol, Wojciech Ślusarczyk, Magdalena Larysz-Brysz, Krzysztof Łabuzek, Bartosz Kapustka, Rafał Staszkiewicz, Paulina Rosicka, Katarzyna Kalita, Władysław Węglarz, Joanna Lewin-Kowalik
Spinal cord injuries are still a serious problem for regenerative medicine. Previous research has demonstrated that activated microglia accumulate in spinal lesions, influencing the injured tissues in various ways. Therefore, transplantation of activated microglia may have a beneficial role in the regeneration of the nervous system. The present study examined the influence of transplanted activated microglial cells in adult rats with injured spinal cords. Rats were randomly divided into an experimental (M) and control (C) group, and were subjected to non-laminectomy focal injury of spinal cord white matter by means of a high-pressured air stream...
November 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29200481/cervical-laminectomy-with-lateral-mass-screw-fixation-in-cervical-spondylotic-myelopathy-neurological-and-sagittal-alignment-outcome-do-we-need-lateral-mass-screws-at-each-segment
#10
Manoj Dayalal Singrakhia, Nikhil Ramdas Malewar, Sonal Manoj Singrakhia, Shivaji Subhash Deshmukh
Background: Anterior cervical decompression and fusion is the standard procedure used for treating patients with cervical myelopathy. However, these procedures are associated with complications such as pseudarthrosis, construct failure, and neurological complications. Posterior cervical laminectomy and instrumentation is an alternative procedure to treat multilevel cervical myelopathy. In this study, we raised questions whether instrumentation is required at all levels and whether stabilizing the spine in neutral or lordotic contour with indirect decompression leads to neurological improvement with radiological evidence of anterior decompression...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29197345/perioperative-duloxetine-and-etoricoxibto-improve-postoperative-pain-after-lumbar-laminectomy-a-randomized-double-blind-controlled-study
#11
Josef Zekry Attia, Haidy Salah Mansour
BACKGROUND: Duloxetine, Etoricoxib and opioid are of the commonly administered drugs in Lumbar laminectomy. The aim of this study is to assess the effect of perioperative use of Duloxetine in combination with Etoricoxib on postoperative pain and opioid requirements. METHODS: One hundred twenty patients with ASA physical status were enrolled with age between 18 and 70 years. Patients were divided randomly into four groups of 30 patients: group P received placebo, group E received etoricoxib 120 mg, group D received duloxetine 60 mg and group D/E received duloxetine 60 mg capsules and etoricoxib 120 mg; 1 h before surgery and 24 h after...
December 2, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/29192880/negative-pressure-dressing-management-of-recurrent-postoperative-epidural-hematoma-and-uncontrollable-intraoperative-hemorrhage-in-posterior-spine-surgery-report-of-4-cases
#12
Kenneth C Foxx, Addisu Mesfin, Robert Molinari
There is a paucity of literature describing the management of recurrent symptomatic postoperative epidural hematoma or uncontrollable intraoperative hemorrhage in posterior spine surgery. Traditional management with hematoma evacuation and wound closure over suction drains may not be effective in certain cases, and it can lead to recurrence and neurological injury. The authors report 3 cases of recurrent symptomatic postoperative epidural hematoma successfully managed with novel open-wound negative-pressure dressing therapy (NPDT), as well as 1 case of uncontrollable intraoperative hemorrhage that was primarily managed with the same technique...
December 1, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29191390/efficacy-of-intraoperative-lumbar-subarachnoid-drainage-for-prevention-of-cerebrospinal-fluid-leak-after-spinal-cord-tumor-resection
#13
Kazuyoshi Kobayashi, Kei Ando, Kenyu Ito, Mikito Tsushima, Akiyuki Matsumoto, Masayoshi Morozumi, Satoshi Tanaka, Masaaki Machino, Naoki Ishiguro, Shiro Imagama
BACKGROUND: Postoperative cerebrospinal fluid (CSF) leakage is a major clinical problem, and prevention of CSF leakage at the surgical site is an important issue. The goal of the study was to evaluate the efficacy of intraoperative lumbar subarachnoid drainage (LSAD) for prevention of CSF leakage after spinal cord tumor resection. METHODS: The subjects were 97 patients with a cervical or thoracic primary intradural spinal cord tumor who underwent surgery at our hospital...
November 27, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29174237/midline-ligamentum-flavum-cyst-of-the-lumbar-spine-a-case-report
#14
Kevin Shah, Daniel Segui, Sergio Gonzalez-Arias
BACKGROUND: Ligamentum flavum cysts are thought to develop due to facet joint hypermobility however the etiology of these lesions is not completely elucidated. These cysts may lead to compressive pathologies of the spine requiring surgical intervention. CASE REPORT: We report the case of a 63-year-old male with chronic back pain and progressive neurogenic claudication for 6 months. He was found to have a ligamentum flavum cyst situated along the dorsal midline of the lumbar spinal canal contributing to spinal stenosis...
November 23, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29173440/laminectomy-with-or-without-fusion-to-manage-degenerative-cervical-myelopathy
#15
REVIEW
Fahad H Abduljabbar, Alisson R Teles, Rakan Bokhari, Michael Weber, Carlo Santaguida
Stand-alone cervical laminectomy for degenerative cervical myelopathy (DCM) has become increasingly rare due to risk of postlaminectomy kyphosis. This article discusses the biomechanics of cervical degeneration and how laminectomy effects spine stability, and summarizes relevant clinical studies to help guide surgical decision-making for the posterior treatment of DCM. Laminectomy and fusion remains a safe and efficacious treatment. Stand-alone laminectomy should only be used for a highly selected patient population with relative stiff lordotic cervical spines, using care to not disrupt facets and C2 and C7 muscle attachments...
January 2018: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/29173422/history-and-evolution-of-laminoplasty
#16
REVIEW
Yoshitaka Hirano, Yukoh Ohara, Junichi Mizuno, Yasunobu Itoh
Techniques of expansive laminoplasty for degenerative cervical myelopathy and ossified posterior longitudinal ligament are described, focusing on the history of the surgical procedure. Laminectomy was the only approach for posterior decompression before Japanese orthopedic surgeons introduced laminoplasty from the 1970s to the 1980s to overcome the poor outcomes of laminectomy. Recent laminoplasty techniques offer less invasive maneuvers to the posterior cervical muscle structures to reduce axial neck pain and to obtain better functional outcome, but every operation is carried out based on the unchanged initial concept...
January 2018: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/29171651/pulmonary-embolism-occurring-in-a-patient-treated-with-spinal-cord-stimulation
#17
Tülin Arıcı, Mustafa Kurçaloğlu, Meltem Uyar, Can Eyigör
Spinal cord stimulation (SCS) has been shown to be an effective method for treating many chronic pain syndromes. In addition, providing pain relief with SCS can reduce immobilization and complications related to immobilization. The present case describes pulmonary embolism (PE) that occurred in patient being treated with SCS for post-laminectomy syndrome. The possibility of PE must be kept in mind while treating patients with SCS.
October 2017: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
https://www.readbyqxmd.com/read/29155339/body-mass-index-predicts-risk-of-complications-in-lumbar-spine-surgery-based-on-surgical-invasiveness
#18
Olivia J Bono, Gregory W Poorman, Norah Foster, Cyrus M Jalai, Samantha R Horn, Jonathan Oren, Alexandra Soroceanu, Subaraman Ramachandran, Taylor E Purvis, Deeptee Jain, Shaleen Vira, Bassel G Diebo, Breton Line, Daniel M Sciubba, Themistocles S Protopsaltis, Aaron J Buckland, Thomas J Errico, Virginie Lafage, Shay Bess, Peter G Passias
BACKGROUND CONTEXT: Obesity as a comorbidity in spine pathology may increase the risk of complications following surgical treatment. The BMI threshold at which obesity becomes clinically relevant, and the exact nature of that effect, remains poorly understood. PURPOSE: Identify the body mass index (BMI) that independently predicts risk of postoperative complications following lumbar spine surgery. STUDY DESIGN/SETTING: Retrospective review of the National Surgery Quality Improvement Program (NSQIP) years 2011-2013...
November 16, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29155254/association-of-riluzole-and-dantrolene-improves-significant-recovery-after-acute-spinal-cord-injury-in-rats
#19
Bernardo De Caro Martins, Bruno Benetti Junta Torres, Karen Maciel de Oliveira, Mario Sergio Lavor, Carla Maria Osório, Fabiola Bono Fukushima, Isabel Rodrigues Rosado, Eliane Gonçalves de Melo
BACKGROUND CONTEXT: Damage to the spinal cord can result in irreversible impairment or complete loss of motor, sensory, and autonomic functions. Riluzole and dantrolene have been shown to provide neuroprotection by reducing neuronal apoptosis after brain and spinal cord injury (SCI) in several animal models of neurological disorders. As these drugs protect the injured spinal cord through different mechanisms, we investigated the cumulative effects of riluzole and dantrolene. PURPOSE: This study aimed to investigate the neuroprotective efficacy of the combined administration of riluzole and dantrolene in experimental thoracic SCI...
November 15, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29153782/outcomes-of-cervical-laminoplasty-population-level-analysis-of-a-national-longitudinal-database
#20
Anand Veeravagu, Tej D Azad, Michael Zhang, Amy Li, Arjun V Pendharkar, John K Ratliff, Lawrence M Shuer
OBJECTIVE: Cervical laminoplasty is an important alternative to laminectomy in decompressing of the cervical spine. Further evidence to assess the utility of laminoplasty is required. We examine outcomes of cervical laminoplasty via a population level analysis in the United States. METHODS: We performed a population-level analysis using the national MarketScan longitudinal database to analyze outcomes and costs of cervical laminoplasty between 2007 and 2014. Outcomes included postoperative complications, revision rates, and functional outcomes...
November 15, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
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