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https://www.readbyqxmd.com/read/29040496/changes-in-platelet-bax-levels-contribute-to-impaired-platelet-response-to-thrombin-after-cardiopulmonary-bypass-prospective-observational-clinical-and-laboratory-investigations
#1
M Murase, Y Nakayama, D I Sessler, N Mukai, S Ogawa, Y Nakajima
Background: Anucleate platelets can undergo apoptosis in response to various stimuli, as do nucleated cells. Cardiopulmonary bypass (CPB) causes platelet dysfunction and can also activate platelet apoptotic pathways. We therefore evaluated time-dependent changes in blood platelet Bax (a pro-apoptotic molecule) levels and platelet dysfunction after cardiac surgery. Methods: We assessed blood samples obtained from subjects having on-pump or off-pump coronary artery bypass graft surgery (n=20 each)...
October 10, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29036976/-comparison-of-perioperative-serum-thrombomodulin-levels-in-patients-underwent-off-pump-coronary-artery-bypass-grafting-with-and-without-cardiogenic-shock
#2
L Zhang, C Wang, T X Gu, C M Lu, Z W Wang
Objective: To observe the perioperative changes of serum thrombomodulin in patients with and without cardiogenic shock undergoing off-pump coronary artery bypass grafting surgery. Methods: A total of 66 patients with coronary artery disease who underwent off-pump coronary artery bypass grafting surgery between June and December 2015 in our hospital were included in this study.The patients were divided into non-cardiogenic shock group (n=51) and shock group (n=15) according to the absence or presence of cardiogenic shock...
September 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29029526/percutaneous-coronary-intervention-using-drug-eluting-stents-versus-coronary-artery-bypass-graft-surgery-in-left-main-coronary-artery-disease-an-updated-meta-analysis-of-randomized-clinical-trials
#3
Lei Gao, Yuqi Liu, Zhijun Sun, Yabin Wang, Feng Cao, Yundai Chen
OBJECTIVES: To compare the safety and efficacy of percutaneous coronary intervention (PCI) using drug-eluting stent (DES) and coronary artery bypass graft (CABG) for the treatment of left main coronary artery (LMCA) disease. BACKGROUND: Several new randomized trials have recently examined the clinical outcomes of PCI and CABG in LMCA disease. However, the results of these studies were inconsistent. MATERIALS AND METHODS: We searched five online electronic databases to identify all the randomized clinical trials assessing the outcomes of PCI using DES and CABG in patients with LMCA...
September 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29029008/complete-arterial-revascularization-using-bilateral-internal-mammary-artery-in-t-graft-technique-for-multivessel-coronary-artery-disease-in-on-or-off-pump-approach-does-gender-lose-its-historical-impact-on-clinical-outcome
#4
Friedrich-Christian Rieß, Christian-Alexander Behrendt, Wagma Amin, Stefan Heller, Lorenz Hansen, Stephan Winkel, Jan Stripling, Henrik Christian Rieß
OBJECTIVES: Higher rates of mortality and morbidity have been reported in women undergoing coronary artery bypass grafting (CABG) compared with men. Different revascularization techniques (on-pump and off-pump) might influence this outcome. METHODS: We retrospectively analysed 3445 consecutively recruited patients (all comers) undergoing complete arterial CABG (CACABG) at a single centre between January 2000 and December 2012. CACABG was performed in all patients using bilateral skeletonized internal mammary artery in T-graft technique, either on-pump (n = 2216) or off-pump (n = 1229)...
September 25, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29028651/endoscopic-conduit-harvest-in-coronary-artery-bypass-grafting-surgery-an-ismics-systematic-review-and-consensus-conference-statements
#5
Francis D Ferdinand, John K MacDonald, Husam H Balkhy, Gianluigi Bisleri, Ho Young Hwang, Patricia Northrup, Richard H J Trimlett, Lai Wei, Bob B Kiaii
OBJECTIVE: The purpose of this consensus conference was to develop and update evidence-informed consensus statements and recommendations on harvesting saphenous vein and radial artery via an open as compared with endoscopic technique by systematically reviewing and performing a meta-analysis of randomized and nonrandomized clinical trials. METHODS: All randomized controlled trials and nonrandomized controlled trials included in the first the International Society for Minimally Invasive Cardiothoracic Surgery Consensus Conference and Statements, in 2005 up to November 30, 2015, were included in a systematic review and meta-analysis...
October 13, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29027034/low-intensity-led-therapy-%C3%AE-640%C3%A2-%C3%A2-%C3%A2-20%C3%A2-nm-on-saphenectomy-healing-in-patients-who-underwent-coronary-artery-bypass-graft-a-randomized-double-blind-study
#6
Raimundo de Barros Araújo Júnior, Isabel Clarisse Albuquerque Gonzaga, Gilderlene Alves Fernandes, Andréa Conceição Gomes Lima, Paulo Sergio Tajra Cortelazzi, Rauirys Alencar de Oliveira, Renata Amadei Nicolau
Myocardial revascularization surgery (CABG) is the most appropriate treatment for coronary artery disease. Currently, the great challenge is to reduce postoperative complications, such as wound infections, dehiscence, pain, and patients' quality of life. The saphenectomy is the target of complications in 10% of cases, which can cause greater morbidity, time, and cost of hospitalization. Studies show that low-intensity laser or light-emitted diode (LED) therapy promotes positive biomodulation of the tissue repair process, culminating in a lower incidence of dehiscence, pain reduction, and improvement in quality of life...
October 13, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29023185/effectiveness-of-low-intensity-laser-therapy-on-tissue-repair-following-saphenectomy-in-patients-who-underwent-coronary-artery-bypass-graft-a-randomized-double-blind-study
#7
Isabel Clarisse Albuquerque Gonzaga, Raimundo de Barros Araújo, Andréa Conceição Gomes Lima, Gilderlene Alves Fernandes, Paulo Sérgio Cortellazi, Rauirys Alencar de Oliveira, Renata Amadei Nicolau
OBJECTIVE: To verify the effectiveness of low-intensity laser therapy (LLLT) on tissue repair following saphenectomy during postoperative period in patients having undergone coronary artery bypass graft (CABG). MATERIALS AND METHODS: A randomized clinical trial, controlled and double-blind study was conducted with 40 volunteers, divided into 2 groups: a placebo group (PG, n = 20) and a laser group (LG, n = 20). The patients in the LG group were irradiated with laser during saphenectomy (InGaAlP, λ 660 nm, energy density 6 J/cm(2)) daily from the first to the fourth postoperative day...
October 12, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29022414/iatrogenic-breast-infarct-following-coronary-artery-bypass-graft-surgery-with-harvesting-of-left-internal-mammary-artery
#8
Jacob Sweeney, Matthew Skovgard, Syed Hoda
No abstract text is available yet for this article.
October 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29019879/percutaneous-coronary-intervention-versus-cardiac-bypass-surgery-for-left-main-coronary-artery-disease-a-trial-sequential-analysis
#9
Yicong Ye, Ming Yang, Shuyang Zhang, Yong Zeng
BACKGROUND: Several updated meta-analyses comparing percutaneous coronary intervention (PCI) with coronary artery bypass grafting (CABG) for left main coronary artery disease (LM CAD) have been published recently. However, the risk of false-positive results could be high in conventional updated meta-analyses due to repetitive testing of accumulating data. Therefore, we compared these treatment approaches via trial sequential analysis (TSA). METHODS: The MEDLINE, Embase, and Cochrane Central Register of Controlled Trials databases were searched for published randomized controlled trials (RCTs) or subgroups of RCTs comparing PCI and CABG in patients with LM CAD...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29017569/impact-of-severe-left-ventricular-dysfunction-on-in-hospital-and-mid-term-outcomes-of-chinese-patients-undergoing-first-isolated-off-pump-coronary-artery-bypass-grafting
#10
Qiang Ji, Li Min Xia, Yun Qing Shi, Run Hua Ma, Jin Qiang Shen, Wen Jun Ding, Chun Sheng Wang
BACKGROUND: Few studies focused on evaluating the impacts of preoperative severe left ventricular dysfunction on clinical outcomes of patients undergoing off-pump coronary artery bypass grafting surgery (OPCAB). This single center retrospective study aimed to evaluate the impacts of severe left ventricular dysfunction on in-hospital and mid-term clinical outcomes of Chinese patients undergoing first, scheduled, and isolated OPCAB surgery. METHODS: From January 2010 to December 2014, 2032 eligible patients were included in this study and were divided into 3 groups: a severe group (patients with preoperative left ventricular ejection fraction (LVEF) of ≤35%, n = 128), an impaired group (patients with preoperative LVEF of 36-50%, n = 680), and a normal group (patients with preoperative LVEF of >50%, n = 1224)...
October 10, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29016380/comparison-of-del-nido-cardioplegia-with-blood-cardioplegia-in-adult-combined-surgery
#11
Raphael Hamad, Anthony Nguyen, Éric Laliberté, Denis Bouchard, Yoan Lamarche, Ismail El-Hamamsy, Philippe Demers
OBJECTIVE: del Nido solution (DNS) is a single-dose cardioplegia designed for pediatric use proposed to offer superior myocardial protection in adults. However, few data support this claim. We hypothesized that DNS and modified blood cardioplegia solution (BS) provide equivalent safety in combined adult valve surgery. METHODS: Between November 2014 and December 2015, 25 patients underwent primary aortic valve replacement and concomitant coronary artery bypass grafting (CABG) with DNS...
October 7, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/28994689/a-case-report-of-combined-radical-pericardiectomy-and-beating-heart-coronary-artery-bypass-grafting-in-a-patient-with-tubercular-chronic-constrictive-pericarditis-with-coronary-artery-disease
#12
Gauranga Majumdar, Surendra Kumar Agarwal, Shantanu Pande, Bipin Chandra, Prabhat Tewari
We here report a successful midterm outcome following combined off-pump radical pericardiectomy and coronary artery bypass surgery (CABG) in a 65-year-old male patient who was suffering from chronic constrictive calcified tubercular pericarditis with coronary artery disease. Simultaneous off-pump CABG and radical pericardiectomy for nonsurgical constrictive pericarditis is reported very rarely in English literature.
October 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28994674/relationship-between-perioperative-left-atrial-appendage-doppler-velocity-estimates-and-new-onset-atrial-fibrillation-in-patients-undergoing-coronary-artery-bypass-graft-surgery-with-cardiopulmonary-bypass
#13
Kunal Sarin, Sandeep Chauhan, Akshay K Bisoi, Poonam Malhotra Kapoor, Parag Gharde, Arindam Choudhury
BACKGROUND: Literature search reveals that postoperative atrial fibrillation (POAF) occurs in 15%-40% of coronary artery bypass graft (CABG) patients. Although several risk models exist for predicting the development of POAF, few have studied left atrial appendage (LAA) velocity. We hypothesize that an association between LAA velocity and development of POAF exists. DESIGN AND METHODS: Single institution university hospital prospective observational clinical study performed between May 2016 and November 2016 in 96 adult patients undergoing CABG surgery utilizing cardiopulmonary bypass (CPB)...
October 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28993118/th17-treg-ratio-in-serum-predicts-onset-of-postoperative-atrial-fibrillation-after-off-pump-coronary-artery-bypass-graft-surgery
#14
Yi He, Xi Chen, Xuejun Guo, Hang Yin, Nan Ma, Min Tang, Hao Liu, Ju Mei
BACKGROUND: The aim of this study is to identify whether the balance between T helper 17 (Th17) cells and CD4(+)CD25(+)Foxp3(+) regulatory T (Treg) cells could predict the postoperative atrial fibrillation (POAF) after coronary artery bypass graft surgery (CABG). METHODS: We enrolled 88 patients from Xinhua Hospital who received off-pump CABG (OPCABG) surgery. The baseline characteristics of patients were recorded. The preoperative variables C-reactive protein (CRP) level, left atrial (LA) volume, EuroSCORE I score, CHADS2 score, and CHA2DS2-VASc score were calculated at enrolment...
September 23, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28992207/propensity-score-based-methods-in-comparative-effectiveness-research-on-coronary-artery-disease
#15
Alexandra G Ellis, Thomas A Trikalinos, Benjamin S Wessler, John B Wong, Issa J Dahabreh
This review examines the conduct and reporting of observational studies using propensity score-based methods to compare coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), or medical therapy for patients with coronary artery disease. A systematic selection process identified 48 studies: 20 CABG vs. PCI; 21 bare-metal stents vs. drug-eluting stents; 5 CABG vs. medical therapy; 1 PCI vs. medical therapy; and 1 drug-eluting stents vs. balloon angioplasty. Of 32 studies reporting information on variable selection, 7 relied exclusively on statistical criteria for the association of covariates with treatment and 5 used such criteria to determine whether product or non-linear terms should be included in the propensity score model...
July 13, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28992151/a-comparison-of-in-hospital-acute-myocardial-infarction-management-between-portugal-and-the-united-states-2000-2010
#16
Mariana F Lobo, Vanessa Azzone, Luís Filipe Azevedo, Bruno Melica, Alberto Freitas, Leonor Bacelar-Nicolau, Francisco N Rocha-Gonçalves, Cláudia Nisa, Armando Teixeira-Pinto, José Pereira-Miguel, Frederic S Resnic, Altamiro Costa-Pereira, Sharon-Lise Normand
Objective: To compare healthcare in acute myocardial infarction (AMI) treatment between contrasting health systems using comparable representative data from Europe and USA. Design: Repeated cross-sectional retrospective cohort study. Setting: Acute care hospitals in Portugal and USA during 2000-2010. Participants: Adults discharged with AMI. Interventions: Coronary revascularizations procedures (percutaneous coronary intervention (PCI), coronary artery bypass graft (CABG) surgery)...
October 1, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28991056/ultrafast-track-robotic-assisted-minimally-invasive-coronary-artery-surgical-revascularization
#17
Christopher L Tarola, Hussein A Al-Amodi, Sankar Balasubramanian, Stephanie A Fox, Christopher C Harle, Ivan Iglesias, Kumar Sridhar, Patrick J Teefy, Michael W A Chu, Bob B Kiaii
OBJECTIVE: Contemporary anesthetic techniques have enabled shorter sedation and early extubation in off-pump and minimally invasive coronary artery bypass (CABG) surgery. Robotic-assisted CABG represents the optimal surgical approach for ultrafast track anesthesia, with patients able to bypass the cardiac surgical intensive care unit with recovery in the postanesthesia care unit (PACU) and inpatient ward. METHODS: In-hospital postoperative outcomes from ninety patients who underwent either elective or urgent robotically-assisted CABG at our institution were reviewed...
October 4, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/28988641/sex-dependent-effects-of-diabetes-mellitus-on-the-revascularization-rate-in-mid-term-follow-up-of-young-patients-with-coronary-artery-disease
#18
Masoumeh Lotfi-Tokaldany, Seyed Hesameddinn Abbasi, Abbasali Karimi, Seyed Ebrahim Kassaian, Tahereh Davarpasand, Arash Jalali, Saeed Sadeghian
AIMS: We investigated the association between Type-2 diabetes mellitus (DM) and the need for revascularization at a 5-year follow-up of young coronary artery disease patients and the role of sex in this regard. METHODS: Among 1121 young (males≤45, and females≤55years) patients (female: 49.7%) from Tehran Heart Center's Premature Coronary Atherosclerosis Cohort, 371(33.1%) had diabetes prior to angiography. Revascularization was considered as either percutaneous coronary intervention or coronary artery bypass graft surgery...
July 4, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28988183/neurological-outcome-after-minimal-invasive-coronary-artery-surgery-nomics-protocol-for-an-observational-prospective-cohort-study
#19
Kristof Nijs, Jeroen Vandenbrande, Fidel Vaqueriza, Jean-Paul Ory, Alaaddin Yilmaz, Pascal Starinieri, Jasperina Dubois, Luc Jamaer, Ingrid Arijs, Björn Stessel
INTRODUCTION: Adverse neurocognitive outcomes are still an important cause of morbidity and mortality after cardiac surgery. The most common neurocognitive disorders after conventional cardiac surgery are postoperative cognitive dysfunction (POCD), stroke and delirium. Minimal invasive cardiac procedures have recently been introduced into practice. Endoscopic coronary artery bypass grafting (Endo-CABG) is a minimal invasive cardiac procedure based on the conventional CABG procedure. Neurocognitive outcome after minimal invasive cardiac surgery, including Endo-CABG, has never been studied...
October 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/28987394/staphylococcus-aureus-prevention-strategies-in-cardiac-surgery-a-cost-effectiveness-analysis
#20
Jonathan C Hong, Manoj K Saraswat, Trevor A Ellison, J Trent Magruder, Todd Crawford, Julia M Gardner, William V Padula, Glenn J Whitman
BACKGROUND: Cardiac surgery patients colonized with Staphylococcus aureus have a greater risk of surgical site infection (SSI). The purpose of this study was to evaluate the cost-effectiveness of decolonization strategies to prevent SSIs. METHODS: We compared three decolonization strategies: universal decolonization (UD), all subjects treated; targeted decolonization (TD), only S aureus carriers treated; and no decolonization (ND). Decolonization included mupirocin, chlorhexidine, and vancomycin...
October 4, 2017: Annals of Thoracic Surgery
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