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https://www.readbyqxmd.com/read/29334194/enrollment-in-early-phase-clinical-trials-in-pediatric-oncology-the-experience-at-institut-curie
#1
Aurore Surun, Marie-Églantine Dujaric, Isabelle Aerts, Daniel Orbach, Irène Jiménez, Hélène Pacquement, Gudrun Schleiermacher, Franck Bourdeaut, Jean Michon, Jean-Claude K Dupont, François Doz
BACKGROUND: The European Paediatric Regulation was introduced in 2007 to facilitate access to new medicines for children. Our study explored accessibility of early-phase trials in pediatric oncology, in line with the European Paediatric Regulation, to identify the reasons for not inviting patients to participate, parents' refusal, or inclusion failure. PROCEDURE: We conducted a retrospective chart review at Institut Curie, Paris, for all pediatric patients whose cancer progressed despite known effective treatments between July 2010 and December 2013...
January 15, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29327493/a-prospective-cohort-study-of-122-adult-patients-presenting-to-an-otolaryngologist-s-office-with-globus-pharyngeus
#2
Eva Rye Rasmussen, Didde Traerup Schnack, Andreas Tomaas Ravn
OBJECTIVES: To investigate the epidemiology of globus pharyngeus in adult patients presenting to the otolaryngologist's office. Also the predictors of persisting symptoms, prevalence of anxiety and the effect of clinical assessment were analyzed. DESIGN: This was a prospective cohort study. Follow-up was done using a postal questionnaire. SETTING: One otolaryngologists' office comprising three medical doctors. PARTICIPANTS: 122 consecutive globus patients presenting to one otolaryngology office in a one-year period...
January 11, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29325816/lgbt-cultural-competence-and-interventions-to-help-oncology-nurses-and-other-health-care-providers
#3
REVIEW
Asa Radix, Shail Maingi
OBJECTIVES: To define and give an overview of the importance of lesbian, gay, bisexual, and transgender (LGBT) cultural competency and offer some initial steps on how to improve the quality of care provided by oncology nurses and other health care professionals. DATA SOURCES: A review of the existing literature on cultural competency. CONCLUSION: LGBT patients experience cancer and several other diseases at higher rates than the rest of the population...
January 8, 2018: Seminars in Oncology Nursing
https://www.readbyqxmd.com/read/29324962/care-provided-by-the-father-to-the-child-with-cancer-under-the-influence-of-masculinities-qualitative-meta-synthesis
#4
Naiara Barros Polita, Willyane de Andrade Alvarenga, Ana Carolina Andrade Biaggi Leite, Jeferson Santos Araújo, Louise Bittencourt Paes Abreu Dos Santos, Márcia Maria Fontão Zago, Francine de Montigny, Lucila Castanheira Nascimento
OBJECTIVE: To synthesize and interpret findings and conclusions of qualitative research addressing the experience of the father in the care of the child with cancer. METHOD: Meta-synthesis of 16 qualitative studies from six databases, analyzed through taxonomic analysis. RESULTS: Child and adolescent cancer have several repercussions on the daily life of the father, especially related to the stigma around the disease, the fear of the unknown and the social and family role...
January 2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29319014/video-assisted-thoracoscopic-surgery-lobectomy-the-first-indian-report
#5
Arvind Kumar, Belal Bin Asaf, Harsh Vardhan Puri, Manish Kumar Sharma, Vijay C Lingaraju, Vimesh S Rajput
INTRODUCTION: The fear of pleural adhesions and densely stuck lymph nodes in India, a country where tuberculosis is endemic, is one major factor keeping our surgeons away from video-assisted thoracoscopic surgery (VATS) lobectomy. In this paper, we aim to report our experience with performing VATS lobectomy in 102 cases using a standardised three-port anterior approach. MATERIALS AND METHODS: Between March 2012 and September 2016, we performed 102 VATS lobectomies...
January 10, 2018: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/29310495/outcome-of-carotid-and-subclavian-blowout-syndrome-in-patients-with-pharynx-and-larynx-carcinoma-passing-a-standardized-multidisciplinary-treatment
#6
Constanze Gahleitner, Benedikt Hofauer, Katharina Storck, Andreas Knopf
BACKGROUND: Carotid blowout syndrome (CBS) is one of the most feared emergencies in the head and neck surgery and tends to occur in patients with head and neck cancer, wound complications, pharyngocutaneous fistulas, or after radio(chemo)therapy. CBS is always life threatening and associated with a 50% mortality/morbidity rate. METHODS: Between 2007 and 2015, a total of 51 patients who developed CBS caused by the tumour masses or after radio(chemo)therapy were included...
January 8, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29288390/body-image-and-psychological-distress-in-women-with-breast-cancer-a-french-online-survey-on-patients-perceptions-and-expectations
#7
Camille Pierrisnard, Marjorie Baciuchka, Julien Mancini, Pascal Rathelot, Patrice Vanelle, Marc Montana
BACKGROUND: Altered body image caused by alopecia, loss of eyebrows or eyelashes, or mastectomy is a major source of psychological distress in women with breast cancer. OBJECTIVE: To identify and to assess patients' perceptions and expectations regarding altered body image. METHOD: Opinion survey conducted among patients treated for breast cancer and member of French online support groups. Anonymous online self-administered survey sent to women with breast cancer...
December 29, 2017: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/29284242/lay-beliefs-on-polish-oncology-in-the-evaluation-of-healthy-individuals
#8
Małgorzata Synowiec-Piłat
INTRODUCTION: Poland is among the countries which reported the highest rates of mortality from cancer. The health behaviours of people are influenced, among other things, by their beliefs about cancer, but their evaluation of oncological institutions and specialists seems also to be of great importance. Objectives. 1. How the respondents evaluate Polish oncology: a) the conditions of treatment in oncology hospitals, b) access to oncological medical services, c) the competence of oncologists...
December 23, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/29280089/developing-a-mass-media-campaign-to-promote-mammography-awareness-in-african-american-women-in-the-nation-s-capital
#9
Sherrie Flynt Wallington, Bridget Oppong, Marquita Iddirisu, Lucile L Adams-Campbell
This study developed and examined the reach and impact of a culturally appropriate mass media campaign pilot, designed to increase awareness about the importance of mammography screening and the available community mammography services for low-income African American women ages 40 and above. We conducted formative research using focus groups to inform campaign development, resulting in five emergent themes-good breast health, holistic views of healthiness, cancer fatalism, fear of mammogram machines, and mammogram affordability...
December 26, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/29273311/investigating-barriers-to-genetic-counseling-and-germline-mutation-testing-in-women-with-suspected-hereditary-breast-and-ovarian-cancer-syndrome-and-lynch-syndrome
#10
Josephine Shaw, Caroline Bulsara, Paul A Cohen, Madeleine Gryta, Cassandra B Nichols, Lyn Schofield, Sarah O'Sullivan, Nicholas Pachter, Sarah J Hardcastle
OBJECTIVE: The aim of the current study was to explore barriers to genetic counseling and testing in women with gynecological cancers deemed at significant risk of carrying a germline mutation. METHODS: A qualitative study using semi-structured interviews and inductively analysed thematically. Eight patients with ovarian or endometrial cancer participated in individual semi-structured telephone interviews that assessed motivation for genetic counseling and testing, perceived benefits and barriers, timing of the approach, perceptions of the referral process to genetic services and locus of control in relation to cancer and health...
December 12, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/29261570/quality-of-life-patient-reported-outcomes-for-locally-advanced-cutaneous-melanoma
#11
Evan S Weitman, Matthew Perez, John F Thompson, Robert H I Andtbacka, Jo Dalton, Mona L Martin, Talia Miller, Chad Gwaltney, David Sarson, Eric Wachter, Jonathan S Zager
Locally advanced cutaneous melanoma has marked quality-of-life implications; however, the patient experience of symptom management and subsequent impact on quality of life has not been well described. This study aims to address the impact on patients of advanced cutaneous melanoma through qualitative interviews. Adults with stage IIIB, IIIC, or IV (M1a) cutaneous melanoma were recruited from two cancer centers in the USA and one in Australia. Telephone interviews were conducted to assess how locoregionally advanced cutaneous melanoma impacted everyday life...
December 19, 2017: Melanoma Research
https://www.readbyqxmd.com/read/29261524/core-set-of-patient-reported-outcomes-in-pancreatic-cancer-coprac-an-international-delphi-study-among-patients-and-health-care-providers
#12
Lennart B van Rijssen, Arja Gerritsen, Inge Henselmans, Mirjam A Sprangers, Marc Jacobs, Claudio Bassi, Olivier R Busch, Carlos Fernández-Del Castillo, Zhi Ven Fong, Jin He, Jin-Young Jang, Ammar A Javed, Sun-Whe Kim, Laura Maggino, Abhishek Mitra, Vikas Ostwal, Silvia Pellegrini, Shailesh V Shrikhande, Johanna W Wilmink, Christopher L Wolfgang, Hanneke W van Laarhoven, Marc G Besselink
OBJECTIVE: To establish an international core set of patient-reported outcomes (PROs) selected by both patients and healthcare providers (HCPs) from the United States (US), Europe, and Asia. SUMMARY BACKGROUND DATA: PROs are increasingly recognized in pancreatic cancer studies. There is no consensus on which of the many available PROs are most important. METHODS: A multicenter Delphi study among patients with pancreatic cancer (curative- and palliative-setting) and HCPs in 6 pancreatic centers in the US (Baltimore, Boston), Europe (Amsterdam, Verona), and Asia (Mumbai, Seoul) was performed...
December 19, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29260390/parent-perspectives-and-preferences-for-strategies-regarding-nonsedated-mri-scans-in-a-pediatric-oncology-population
#13
Breya Walker, Heather M Conklin, Doralina L Anghelescu, Lacey P Hall, Wilburn E Reddick, Robert Ogg, Lisa M Jacola
PURPOSE: Children with cancer frequently require MRI scans for clinical purposes. Sedation with general anesthesia (GA) is often used to promote compliance, reduce motion, and alleviate anxiety. The use of GA for MRI scans is costly in terms of time, personnel, and medications. In addition, prominent risks are associated with anesthesia exposure in patients with complex medical conditions. Successful behavioral interventions have been implemented in clinical research settings to promote scan success and compliance...
December 19, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29251694/existential-distress-and-meaning-focused-interventions-in-cancer-survivorship
#14
Sigrun Vehling, Rebecca Philipp
PURPOSE OF REVIEW: Cancer can challenge fundamental assumptions about security, controllability and life priorities, which may lead to clinically relevant existential distress. We review recent studies on the prevalence of existential distress in cancer survivors, its distinctness from other distress concepts and interventions to address cancer-specific existential challenges. We further describe psychological mechanisms that may underlie change resulting from such interventions. RECENT FINDINGS: One-third to one-half of cancer survivors experienced existential fears and concerns related to reduced control, identity and uncertainty about the future...
December 14, 2017: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29251693/the-fear-of-cancer-recurrence-literature-continues-to-move-forward-a-review-article
#15
Christine Maheu, Jacqueline Galica
PURPOSE OF REVIEW: The volume of literature addressing fear of cancer recurrence (FCR) is rapidly increasing. A summary of key developments in the research and treatment of FCR was published by Sharpe et al. in 2017, and the current review focuses on works published thereafter. RECENT FINDINGS: A comprehensive literature review was conducted to provide an up-to-date summary of peer-reviewed publications focusing on FCR. The search consisted of the most recent FCR reports published between 2016 and 2017, which can be broadly categorized as: methods of assessment; associations with FCR; FCR and caregivers; and FCR interventions...
December 14, 2017: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29243201/should-fear-of-adverse-events-influence-the-decision-to-administer-preoperative-therapy-to-patients-with-pancreatic-cancer
#16
EDITORIAL
Matthew H G Katz
No abstract text is available yet for this article.
December 14, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29243170/associations-among-physical-symptoms-fear-of-cancer-recurrence-and-emotional-well-being-among-chinese-american-breast-cancer-survivors-a-path-model
#17
Dalnim Cho, Qiao Chu, Qian Lu
PURPOSE: Most existing studies on fear of cancer recurrence (FCR) are exploratory without theoretical underpinnings and have been conducted among non-Hispanic Whites. Based on theoretical models, we hypothesized that more physical symptoms (pain and fatigue) would be associated with higher FCR, which, in turn would be related to lower emotional well-being among Chinese American breast cancer survivors. METHODS: Participants were 77 Chinese American women who were diagnosed with breast cancer of stages 0-III...
December 14, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29241715/engaging-patients-in-decisions-about-cancer-screening-exploring-the-decision-journey-through-the-use-of-a-patient-portal
#18
Steven H Woolf, Alex H Krist, Jennifer Elston Lafata, Resa M Jones, Rebecca R Lehman, Camille J Hochheimer, Roy T Sabo, Dominick L Frosch, Brian J Zikmund-Fisher, Daniel R Longo
INTRODUCTION: Engaging patients to make informed choices is paramount but difficult in busy practices. This study sought to engage patients outside the clinical setting to better understand how they approach cancer screening decisions, including their primary concerns and their preferences for finalizing their decision. METHODS: Twelve primary care practices offering patients an online personal health record invited eligible patients to complete a 17-item online interactive module...
December 11, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29241597/understanding-patient-preference-in-female-pelvic-imaging-transvaginal-ultrasound-and-mri
#19
Michelle D Sakala, Ruth C Carlos, Mishal Mendiratta-Lala, Elisabeth H Quint, Katherine E Maturen
RATIONALE AND OBJECTIVES: Women with pelvic pain or abnormal uterine bleeding may undergo diagnostic imaging. This study evaluates patient experience in transvaginal ultrasound (TVUS) and magnetic resonance imaging (MRI) and explores correlations between preference and symptom severity. MATERIALS AND METHODS: Institutional review board approval was obtained for this Health Insurance Portability and Accountability Act-compliant prospective study. Fifty premenopausal women with pelvic symptoms evaluated by recent TVUS and MRI and without history of gynecologic cancer or hysterectomy were included...
December 11, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29240048/why-patients-are-afraid-of-opioid-analgesics-study-on-opioid-perception-in-patients-treated-for-chronic-pain
#20
Michał Graczyk, Alina Borkowska, Małgorzata Krajnik
INTRODUCTION    Opiophobia is deemed one of the key barriers in effective pain management.  OBJECTIVES    The study aimed to assess overall perception of opioids in cancer patients suffering from and treated for chronic pain, as well as determine the nature of their most common, related fears.  PATIENTS AND METHODS    The study comprised 100 palliative care patients who suffered from chronic cancer or non-cancer pain. Initially, they had to complete a survey exploring their knowledge on analgesics and potential fear of using opioids...
December 14, 2017: Polish Archives of Internal Medicine
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