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Christiane Essoh, Yann Blouin, Guillaume Loukou, Arsher Cablanmian, Serge Lathro, Elizabeth Kutter, Hoang Vu Thien, Gilles Vergnaud, Christine Pourcel
Phage therapy may become a complement to antibiotics in the treatment of chronic Pseudomonas aeruginosa infection. To design efficient therapeutic cocktails, the genetic diversity of the species and the spectrum of susceptibility to bacteriophages must be investigated. Bacterial strains showing high levels of phage resistance need to be identified in order to decipher the underlying mechanisms. Here we have selected genetically diverse P. aeruginosa strains from cystic fibrosis patients and tested their susceptibility to a large collection of phages...
2013: PloS One
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