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https://www.readbyqxmd.com/read/28214734/developmental-toxicity-and-molecular-responses-of-marine-medaka-oryzias-melastigma-embryos-to-ciguatoxin-p-ctx-1-exposure
#1
Meng Yan, Priscilla T Y Leung, Jack C H Ip, Jin-Ping Cheng, Jia-Jun Wu, Jia-Rui Gu, Paul K S Lam
Ciguatoxins are produced by toxic benthic dinoflagellates and cause ciguatera fish poisoning worldwide, but the toxic effects on developing marine fish have not been well investigated. The Pacific ciguatoxin (P-CTX-1), is a potent sodium channel agonist, which is one of the most toxic members among all CTXs. This study evaluated the toxic effects of microinjecting purified Pacific ciguatoxin-1 (P-CTX-1) on embryonic development of marine medaka Oryzias melastigma. A lower 96h-LD50 value was estimated for eleuthero-embryos (1...
February 10, 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/28214073/older-adults-with-ptsd-brief-state-of-research-and-evidence-based-psychotherapy-case-illustration
#2
Joan M Cook, Elissa McCarthy, Steven R Thorp
Although lifetime exposure to potentially traumatic events among older adults is fairly high, rates of full-blown post-traumatic stress disorder (PTSD) are estimated at about 4.5%, a rate lower than that for middle-aged and young adults. Nevertheless, PTSD seems to be an under-recognized and under-treated condition in older adults. Assessment and treatment can be challenging in this population for various reasons, including potential cognitive or sensory decline and comorbid mental and physical disorders. This article provides highlights of the empirical research on PTSD in late life, including information on its effects on cognition and physical health...
January 4, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28213988/-contribution-of-mindfulness-meditation-in-cognitive-behavioral-therapy-for-insomnia
#3
H Vanhuffel, M Rey, I Lambert, D Da Fonseca, F Bat-Pitault
INTRODUCTION: Insomnia is considered to be a serious public health issue affecting approximately 10% of adults. Chronic insomnia may increase the risk of health problem, psychological vulnerability and proneness to accidents. Cognitive behavioral therapy for insomnia (CBT-I) is recommended as the first line of treatment. Even though CBT-I is widely considered as an effective therapy, 20 to 30% of patients do not respond to this treatment. Mindfulness therapy, known to reduce rumination and stress, could be an interesting complement to enhance CBT-I...
February 14, 2017: L'Encéphale
https://www.readbyqxmd.com/read/28212519/early-calibration-of-the-hpa-axis-by-maternal-psychopathology
#4
Heidemarie Laurent
Given the central role of stress-responsive neurophysiology in mental and physical health, it is important to understand how particular patterns of stress responsivity may become entrained by the early caregiving environment. In this study we investigated links between maternal depression and anxiety symptom profiles and within-infant development of hypothalamic-pituitary-adrenal (HPA) axis responses from 6 to 18 months of life. Associations with infant cognitive and social-emotional development were also tested to gauge the adjustment implications of HPA response trajectories...
February 1, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28212445/long-term-effects-of-fetal-undernutrition-on-rat-heart-role-of-hypertension-and-oxidative-stress
#5
Pilar Rodríguez-Rodríguez, Angel L López de Pablo, Concha F García-Prieto, Beatriz Somoza, Begoña Quintana-Villamandos, José J Gómez de Diego, Perla Y Gutierrez-Arzapalo, David Ramiro-Cortijo, M Carmen González, Silvia M Arribas
BACKGROUND AND AIMS: Fetal undernutrition is a risk factor for heart disease in both genders, despite the protection of women against hypertension development. Using a rat model of maternal undernutrition (MUN) we aimed to assess possible sex differences in the development of cardiac alterations and the implication of hypertension and cardiac oxidative stress. METHODS: Male and female offspring from rats fed ad libitum (control) or with 50% of the normal daily intake during the second half of gestation (MUN) were used...
2017: PloS One
https://www.readbyqxmd.com/read/28212202/psychometric-evaluation-of-the-adolescent-health-promotion-scale-in-chile-differences-by-socioeconomic-status-and-gender
#6
Cristian A Rojas-Barahona, Jorge Gaete, Esterbina Olivares, Carla E Förster, Eugenio Chandia, Mei-Yen Chen
BACKGROUND: The promotion of healthy behaviors is a relevant issue worldwide, especially among adolescent populations, as this is the developmental stage where most unhealthy behaviors become ingrained. PURPOSE: The aim of this study was to analyze the psychometric properties of the Spanish version of the Adolescent Health Promotion Scale (AHPS) in a Chilean sample of early adolescents. METHODS: The sample was composed of 1,156 adolescents aged 10-14 years from schools in San Felipe, Chile...
February 16, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/28211838/work-satisfaction-burnout-and-gender-based-inequalities-among-ophthalmologists-in-india-a-survey
#7
Akshay Gopinathan Nair, Pooja Jain, Aniruddha Agarwal, Vandana Jain
BACKGROUND: Ophthalmology is a rapidly evolving branch of medicine and advancing technology has raised the bar of patient expectations and outcomes. However, studies that assess physician stress and satisfaction especially in developing countries are limited in literature. OBJECTIVE: This index study aims at looking at the levels of job satisfaction, burnout and perception of gender disparity among ophthalmologists in India. METHODS: An Internet-based survey was sent out to ophthalmologists...
February 17, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28211478/ecology-and-genetics-affect-relative-invasion-success-of-two-echium-species-in-southern-australia
#8
Xiaocheng Zhu, Paul A Weston, Dominik Skoneczny, David Gopurenko, Lucie Meyer, Brendan J Lepschi, Ragan M Callaway, Geoff M Gurr, Leslie A Weston
Echium plantagineum and E. vulgare are congeneric exotics first introduced to Australia in the early 1800 s. There, E. plantagineum is now highly invasive, whereas E. vulgare has a limited distribution. Studies were conducted to evaluate distribution, ecology, genetics and secondary chemistry to shed light on factors associated with their respective invasive success. When sampled across geographically diverse locales, E. plantagineum was widespread and exhibited a small genome size (1 C = 0.34 pg), an annual life cycle, and greater genetic diversity as assessed by DNA sequence analysis...
February 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28210823/non-ablative-erbium-yag-laser-for-the-treatment-of-type-iii-stress-urinary-incontinence-intrinsic-sphincter-deficiency
#9
Adrian Gaspar, Hugo Brandi
The objective of this pilot study was to determine the safety and efficacy of a new non-ablative erbium YAG laser procedure for the treatment of type III stress urinary incontinence (intrinsic sphincter deficiency) in women. Twenty-two patients with a Valsalva leak point pressure less than 60 cm H2O were recruited and treated with a non-ablative erbium laser delivering low fluence pulses inside the whole length of the urethra through a specially designed cannula. Treatment consisted of two treatment sessions with a 3-week interval in-between...
February 16, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28210811/status-and-perception-of-oral-health-in-6-17-year-old-psychiatric-inpatients-randomized-controlled-trial
#10
I M Schüler, B Bock, R Heinrich-Weltzien, K Bekes, M Rudovsky, Ch Filz, C Ligges
AIM: The following are the aims of the study: assessment of oral health status, oral health-related quality of life (OHRQoL) and the effect of oral health care training over OHRQoL in children and adolescents hospitalized with mental disorders. METHODOLOGY: This randomized case controlled prospective interventional study involved 81 child and adolescent psychiatric inpatients (CAP) aged between 6 and 17 years (mean age 10.6 ± 2.4 years), compared to 81 mentally healthy patients attending routine dental examinations (DC group) matched according to age and sex of the CAP group...
February 16, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28210753/puerarin-7-o-glucuronide-a-water-soluble-puerarin-metabolite-prevents-angiotensin-ii-induced-cardiomyocyte-hypertrophy-by-reducing-oxidative-stress
#11
Ning Hou, Bin Cai, Cai-Wen Ou, Zhen-Hui Zhang, Xia-Wen Liu, Mu Yuan, Gan-Jian Zhao, Shi-Ming Liu, Long-Gen Xiong, Jian-Dong Luo, Cheng-Feng Luo, Min-Sheng Chen
This study aimed to investigate the anti-oxidant and anti-hypertrophic effects of puerarin-7-O-glucuronide, a water-soluble puerarin metabolite. The anti-oxidant effects of puerarin-7-O-glucuronide were assessed by measurement of intracellular superoxide levels, total superoxide dismutase (SOD) activity, total anti-oxidant capacity, and glutathione (GSH)/glutathione disulfide (GSSG) ratio in cultured neonatal rat cardiomyocytes (NRCMs) stimulated with the xanthine oxidase (XO)/xanthine (X) system or angiotensin II...
February 16, 2017: Naunyn-Schmiedeberg's Archives of Pharmacology
https://www.readbyqxmd.com/read/28209122/effects-and-meanings-of-a-person-centred-and-health-promoting-intervention-in-home-care-services-a-study-protocol-of-a-non-randomised-controlled-trial
#12
Karin Bölenius, Kristina Lämås, Per-Olof Sandman, David Edvardsson
BACKGROUND: The literature indicates that current home care service are largely task oriented with limited focus on the involvement of the older people themselves, and studies show that lack of involvement might reduce older people's quality of life. Person-centred care has been shown to improve the satisfaction with care and quality of life in older people cared for in hospitals and nursing homes, with limited published evidence about the effects and meanings of person-centred interventions in home care services for older people...
February 16, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28209104/impact-of-gluten-free-diet-on-quality-of-life-in-celiac-patients
#13
R Borghini, M Di Tola, E Salvi, C Isonne, M Puzzono, M Marino, G Donato, A Picarelli
BACKGROUND AND AIM: Celiac disease (CD) is a common gluten-related disorder, whose only treatment is a gluten-free diet (GFD). Since a unique view on psychological consequences of a GFD still lacks, our aim was to assess the quality of life (QoL) and the depression state in symptomatic CD patients after GFD. Socio-demographic features were considered. PATIENTS AND METHODS: 210 adult CD patients were recruited and divided into 3 groups : 70 newly diagnosed patients (​Group A​),70 patients who have been on GFD for 6-12 months (​Group B​), and 70 patients who have been on GFD for more than 12 months (​Group C​)...
September 2016: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/28208996/stress-distribution-under-commercial-denture-liners-a-finite-element-and-clinical-analysis
#14
Rahul Shrivastava, Saurabh Chaturvedi, Ashok Kumar Verma, Mariyum Ali, Amrita Nagendra, Mudita Chaturvedi
INTRODUCTION: Previous studies have shown that 20-30% of denture users have been dissatisfied with their dentures. AIM: To evaluate the stress pattern under elastic and viscoelastic denture liners using 3-Dimensional Finite Element Analysis (FEA) and its clinical correlation using a questionnaire. MATERIALS AND METHODS: The study had both in-vitro and in-vivo phases. In in-vitro phase fabrication of a virtual parametric model of edentulous maxilla and dentures with overlying mucosa was made...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28208905/n-acetylcysteine-combined-with-home-based-physical-activity-effect-on-health-related-quality-of-life-in-stable-copd-patients-a-randomised-controlled-trial
#15
Vijay Tukaram Salve, Jitesh S Atram
INTRODUCTION: Quality of life is adversely affected in Chronic Obstructive Pulmonary Disease (COPD), due to irreversible, progressive nature of the disease and limitations of current treatment options available. One of the important aim of treatment of COPD is to improve Quality of Life (QoL). Cigarette smoke contains numerous free radicals and other oxidants. Oxidative stress has been implicated in pathogenesis, progression of disease and exacerbation in COPD. Pulmonary tuberculosis, outdoor and indoor air pollution and many others are aetiologies of COPD in non-smokers...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28207997/chronically-elevated-bilirubin-protects-from-cardiac-reperfusion-injury-in-the-male-gunn-rat
#16
Bhavisha Bakrania, Eugene F Du Toit, Kevin J Ashton, Karl-Heinz Wagner, John P Headrick, Andrew C Bulmer
AIMS: Bilirubin is associated with reduced risk of cardiovascular disease, as evidenced in conditions of mild hyperbilirubinaemia (Gilbert's Syndrome). Little is known regarding myocardial stress-resistance in hyperbilirubinemic conditions or whether life-long exposure modifies cardiac function, which might contribute to protection from cardiovascular disease. METHODS: Hyperbilirubinemic rats and littermate controls underwent echocardiography at 3, 6 and 12 mo of age, with hearts subsequently assessed for resistance to 30 min of ischaemia...
February 16, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/28207685/trends-in-postpartum-depressive-symptoms-27-states-2004-2008-and-2012
#17
Jean Y Ko, Karilynn M Rockhill, Van T Tong, Brian Morrow, Sherry L Farr
Postpartum depression is common and associated with adverse infant and maternal outcomes (e.g., lower breastfeeding initiation and duration and poor maternal and infant bonding) (1-3). A developmental Healthy People 2020 objective is to decrease the proportion of women delivering a live birth who experience postpartum depressive symptoms (PDS).* To provide a baseline for this objective, CDC sought to describe self-reported PDS overall, by reporting state, and by selected sociodemographic factors, using 2004, 2008, and 2012 data from the Pregnancy Risk Assessment Monitoring System (PRAMS)...
February 17, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28206841/stressors-and-protective-factors-among-veterinary-students-in-new-zealand
#18
Jenny F Weston, Dianne Gardner, Polly Yeung
A study was undertaken to investigate the stressors faced by veterinary students and the protective factors against those stressors. The study was conducted as a workshop during which students collaborated with their peers through an iterative process to identify personal and external factors that contributed to or protected against stress as a veterinary student, and then to suggest strategies that would protect their mental health and well-being. Workload and assessment were the most commonly reported stressors...
2017: Journal of Veterinary Medical Education
https://www.readbyqxmd.com/read/28202135/discovering-pockets-of-complexity-socioeconomic-status-stress-exposure-and-the-nuances-of-the-health-gradient
#19
Scott Schieman, Jonathan Koltai
One of the most pervasive statements about stratification and health identifies the strong inverse relationship-or gradient-between socioeconomic status (SES) and poor health. We elaborate on the ways that the SES-based gradient in stress exposure contributes to nuances in the SES-health association. In analyses of the 2008 National Study of the Changing Workforce, we find some evidence that the inverse association between SES and health outcomes is finely graded-but several 'pockets of complexity' emerge. First, education and income have different associations with health and well-being...
March 2017: Social Science Research
https://www.readbyqxmd.com/read/28201830/-subjective-workload-job-satisfaction-and-work-life-balance-of-physicians-and-nurses-in-a-municipal-hospital-in-a-rural-area-compared-to-an-urban-university-hospital
#20
Michael Körber, Klaus Schmid, Hans Drexler, Johannes Kiesel
Medical and nursing shortages in rural areas represent a current serious public health problem. The healthcare of the rural population is at risk. This study compares perceived workload, job satisfaction and work-life balance of physicians and nurses at a clinic in a rural area with two clinics of a University hospital. Physicians and nurses were interviewed anonymously with a standardized questionnaire (paper and pencil), including questions on job satisfaction, subjective workload and work-life balance. The response rate was almost 50% in the University hospital as well as in the municipal hospital...
February 15, 2017: Das Gesundheitswesen
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