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https://www.readbyqxmd.com/read/27933428/in-6-to-8-year-old-children-cardiorespiratory-fitness-moderates-the-relationship-between-severity-of-life-events-and-health-related-quality-of-life
#1
Markus Gerber, Katharina Endes, Serge Brand, Christian Herrmann, Flora Colledge, Lars Donath, Oliver Faude, Henner Hanssen, Uwe Pühse, Lukas Zahner
PURPOSE: In children, the pathways by which physical activity and fitness are associated with physical and psychological wellbeing are still not fully understood. The present study examines for the first time in young children whether high levels of cardiorespiratory fitness and physical activity moderate the relationship between severity of life events and health-related quality of life. METHODS: Three hundred and seventy-eight children (188 girls, 190 boys, M age = 7...
December 8, 2016: Quality of Life Research
https://www.readbyqxmd.com/read/27932530/affective-alterations-in-patients-with-cushing-s-syndrome-in-remission-are-associated-with-decreased-bdnf-and-cortisone-levels
#2
E Valassi, I Crespo, B G Keevil, A Aulinas, E Urgell, A Santos, P J Trainer, S M Webb
OBJECTIVE: Affective alterations and poorer quality of life often persist in patients with Cushing's syndrome (CS) in remission. Brain-derived neurotrophic factor (BDNF) regulates the hypothalamic-pituitary-adrenal axis (HPA) and is highly expressed in brain areas controlling mood and response to stress. Our aims were to assess affective alterations after long-term remission of CS and evaluate whether they are associated with serum BDNF, salivary cortisol (SalF) and/or cortisone (SalE) concentrations...
February 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/27932062/experiencing-neonatal-maternal-separation-increased-pain-sensitivity-in-adult-male-mice-involvement-of-oxytocinergic-system
#3
Hossein Amini-Khoei, Shayan Amiri, Ali Mohammadi-Asl, Sakineh Alijanpour, Simin Poursaman, Arya Haj-Mirzaian, Mojgan Rastegar, Azam Mesdaghinia, Hamid Reza Banafshe, Ehsanollah Sadeghi, Elika Samiei, Shahram Ejtemaie Mehr, Ahmad Reza Dehpour
Early-life stress adversely affects the development of the brain, and alters a variety of behaviors such as pain in later life. In present study, we investigated how early-life stress (maternal separation or MS) can affect the nociceptive response later in life. We particularly focused on the role of oxytocin (OT) in regulating nociception in previously exposed (MS during early postnatal development) mice that were subjected to acute stress (restraint stress or RS). Further, we evaluated whether such modulation of pain sensation in MS mice are regulated by shared mechanisms of the OTergic and opioidergic systems...
November 30, 2016: Neuropeptides
https://www.readbyqxmd.com/read/27931182/exposure-of-bovine-oocytes-and-embryos-to-elevated-non-esterified-fatty-acid-concentrations-integration-of-epigenetic-and-transcriptomic-signatures-in-resultant-blastocysts
#4
K L J Desmet, V Van Hoeck, D Gagné, E Fournier, A Thakur, A M O'Doherty, C P Walsh, M A Sirard, P E J Bols, J L M R Leroy
BACKGROUND: Metabolic stress associated with negative energy balance in high producing dairy cattle and obesity in women is a risk factor for decreased fertility. Non-esterified fatty acids (NEFA) are involved in this pathogenesis as they jeopardize oocyte and embryo development. Growing evidence indicates that maternal metabolic disorders can disturb epigenetic programming, such as DNA methylation, in the offspring. Oocyte maturation and early embryo development coincide with methylation changes and both are sensitive to adverse environments...
December 8, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27930959/social-support-negative-maltreatment-related-cognitions-and-posttraumatic-stress-symptoms-in-children-and-adolescents
#5
A Münzer, H G Ganser, L Goldbeck
Social support by family, friends and significant others is known to buffer the impact of adverse life events on children's well-being and functioning, however little is known about pathways explaining this association. We investigated whether maltreatment-related cognitions mediate the association between social support and posttraumatic stress symptoms (PTSS). Furthermore, age was introduced as moderator. We assessed the history of maltreatment in 200 maltreated children and adolescents (age 8-17 years) using a semi-structured interview...
December 5, 2016: Child Abuse & Neglect
https://www.readbyqxmd.com/read/27930942/trocar-guided-trans-vaginal-mesh-surgery-for-pelvic-organ-prolapse-effects-on-urinary-continence-and-anatomical-and-functional-outcomes-a-prospective-observational-study
#6
F Natale, E Costantini, C La Penna, E Illiano, R Balsamo, A Carbone, M Cervigni
OBJECTIVE: Primary objective of this study was to assess the effects of trocar-guided transvaginal mesh surgery (TVM) on cure and prevention rates for incontinence, without concomitant surgery for Stress Urinary Incontinence (SUI). Our secondary objectives were anatomical outcomes, relief of symptoms and effect on quality of life (QoL). STUDY DESIGN: This prospective observational study evaluated women who underwent TVM for symptomatic stage >2 Pelvic Organ Prolapse (POP)...
November 9, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27929329/parents-posttraumatic-stress-after-burns-in-their-school-aged-child-a-prospective-study
#7
Marthe R Egberts, Rens van de Schoot, Rinie Geenen, Nancy E E Van Loey
OBJECTIVE: This prospective study examined the course and potential predictors of parents' posttraumatic stress symptoms (PTSS) after burn injury in their child (Age 8 to 18 years). METHOD: One hundred eleven mothers and 91 fathers, representing 118 children, participated in the study. Within the first month after the burn event and subsequently at 3, 12, and 18 months postburn, both parents completed the Impact of Event Scale (IES). Parental emotions related to the burn event and appraisal of threat to the child's life were assessed, which were investigated in a multilevel regression model...
December 8, 2016: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/27926461/long-chain-polyunsaturated-fatty-acids-regulation-of-ppars-signaling-relationship-to-tissue-development-and-aging
#8
REVIEW
Francisca Echeverría, Macarena Ortiz, Rodrigo Valenzuela, Luis A Videla
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that function as ligand-dependent transcription factors that can be activated by different types of fatty acids (FAs). Three isoforms of PPARs have been identify, namely, PPARα, PPARβ/δ, and PPARγ, which are able to bind long-chain polyunsaturated FAs (LCPUFAs), n-3 LCPUFAs being bound with greater affinity to achieve activation. FA binding induces a conformational change of the nuclear receptors, triggering the transcription of specific genes including those encoding for various metabolic and cellular processes such as FA β-oxidation and adipogenesis, thus representing key mediators of lipid homeostasis...
November 2016: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/27922915/lifestyle-behaviors-perceived-stress-and-inflammation-of-individuals-with-chronic-graft-versus-host-disease
#9
Debra Lynch Kelly, Debra E Lyon, Deidre Periera, Cynthia Garvan, John Wingard
BACKGROUND: Stress is a potent immunomodulator contributing to chronic conditions. Chronic graft-versus-host disease (cGVHD) is a life-threatening late effect of allogeneic hematopoietic cell transplantation associated with stress and exaggerated immune response that may be associated to lifestyle behaviors. OBJECTIVE: The aim of this study is to explore associations among lifestyle behaviors, perceived stress, and inflammation of individuals with cGVHD. METHODS: A secondary analysis from a prospective observational study of 24 adults (≥18 years) with cGVHD was conducted...
December 5, 2016: Cancer Nursing
https://www.readbyqxmd.com/read/27922725/resilience-and-traumatic-brain-injury-among-iraq-afghanistan-war-veterans-differential-patterns-of-adjustment-and-quality-of-life
#10
Timothy R Elliott, Yu-Yu Hsiao, Nathan A Kimbrel, Eric Meyer, Bryann B DeBeer, Suzy Bird Gulliver, Oi-Man Kwok, Sandra B Morissette
OBJECTIVE: We examined the degree to which a resilient personality prototype predicted adjustment among war Veterans with and without a traumatic brain injury (TBI) while covarying the level of combat exposure. METHOD: A total of 127 war Veterans (107 men, 20 women; average age = 37 years) participated. Personality prototypes were derived from the Multidimensional Personality Questionnaire (Patrick, Curtain, & Tellegen, 2002). Measures were administered at baseline, and a subset was administered at 4- and 8-month follow-ups...
December 6, 2016: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/27921306/applying-a-family-resilience-framework-in-training-practice-and-research-mastering-the-art-of-the-possible
#11
Froma Walsh
With growing interest in systemic views of human resilience, this article updates and clarifies our understanding of the concept of resilience as involving multilevel dynamic processes over time. Family resilience refers to the functioning of the family system in dealing with adversity: Assessment and intervention focus on the family impact of stressful life challenges and the family processes that foster positive adaptation for the family unit and all members. The application of a family resilience framework is discussed and illustrated in clinical and community-based training and practice...
December 2016: Family Process
https://www.readbyqxmd.com/read/27920720/validation-of-online-versions-of-tinnitus-questionnaires-translated-into-swedish
#12
Karolina Müller, Niklas K Edvall, Esma Idrizbegovic, Robert Huhn, Rilana Cima, Viktor Persson, Constanze Leineweber, Hugo Westerlund, Berthold Langguth, Winfried Schlee, Barbara Canlon, Christopher R Cederroth
Background: Due to the lack of objective measures for assessing tinnitus, its clinical evaluation largely relies on the use of questionnaires and psychoacoustic tests. A global assessment of tinnitus burden would largely benefit from holistic approaches that not only incorporate measures of tinnitus but also take into account associated fears, emotional aspects (stress, anxiety, and depression), and quality of life. In Sweden, only a few instruments are available for assessing tinnitus, and the existing tools lack validation...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/27919307/patterns-and-correlates-of-major-depression-in-chinese-adults-a-cross-sectional-study-of-0-5-million-men-and-women
#13
Y Chen, D Bennett, R Clarke, Y Guo, C Yu, Z Bian, L Ma, Y Huang, Q Sun, N Zhang, X Zheng, J Chen, R Peto, K S Kendler, L Li, Z Chen
BACKGROUND: Worldwide 350 million people suffer from major depression, with the majority of cases occurring in low- and middle-income countries. We examined the patterns, correlates and care-seeking behaviour of adults suffering from major depressive episode (MDE) in China. METHOD: A nationwide study recruited 512 891 adults aged 30-79 years from 10 provinces across China during 2004-2008. The 12-month prevalence of MDE was assessed by the Modified Composite International Diagnostic Interview-short form...
December 6, 2016: Psychological Medicine
https://www.readbyqxmd.com/read/27917815/sleep-quality-differs-between-athletes-and-non-athletes
#14
Havva Demirel
PURPOSE: Sufficient sleep or sleep of sufficient quality is essential for the health of children, adolescents and adults, as sleep influences almost all dimensions of life. The purpose of this study was to investigate the possible positive effects of sportsmanship on sleep quality and to assess the possible differences in sleep quality between athletes and non-athletes. METHODS: Sedentary or non-athletes subjects (n=103) and athletes (n=93) participated in this study...
December 1, 2016: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
https://www.readbyqxmd.com/read/27917588/the-effect-of-liver-transplantation-on-the-quality-of-life-of-the-recipient-s-main-caregiver-a-systematic-review
#15
REVIEW
Alastair L Young, Ian A Rowe, Kate Absolom, Rebecca L Jones, Amy Downing, Nick Meader, Adam Glaser, Giles J Toogood
INTRODUCTION: Liver transplantation (LT) is a transformative, life-saving procedure with life-long sequale for patients and their caregivers. The impact of LT on the patient's main caregiver can be underestimated. We carried out a systematic review of the impact of LT on the Health Related Quality of Life (HRQL) of LT patients' main caregivers. METHODS: We searched 13 medical databases from 1996 to 2015. We included studies with HRQL data on caregivers of patients following LT then quality assessed and narratively synthesized the findings from these studies...
December 5, 2016: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/27917459/predictors-of-stress-generation-in-adolescents-in-mainland-china
#16
Claire J Starrs, John R Z Abela, David C Zuroff, Rhonda Amsel, Josephine H Shih, Shuqiao Yao, Xiong Zhao Zhu, Wei Hong
The current longitudinal study examined whether the personality vulnerabilities of self-criticism and dependency prospectively predicted stress generation in Chinese adolescents. Participants included 1,116 adolescents (588 girls and 528 boys), aged 15 to 18 years from rural, urban and ultra-urban mainland China. Participants completed self-report measures of personality, depressive and anxious symptoms and participated in a clinical interview assessing lifetime history of depression. The occurrence of negative life events was measured using a contextual-threat interview every 6-months for a total period of 18-months...
December 5, 2016: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/27917177/progress-on-optimizing-miscanthus-biomass-production-for-the-european-bioeconomy-results-of-the-eu-fp7-project-optimisc
#17
Iris Lewandowski, John Clifton-Brown, Luisa M Trindade, Gerard C van der Linden, Kai-Uwe Schwarz, Karl Müller-Sämann, Alexander Anisimov, C-L Chen, Oene Dolstra, Iain S Donnison, Kerrie Farrar, Simon Fonteyne, Graham Harding, Astley Hastings, Laurie M Huxley, Yasir Iqbal, Nikolay Khokhlov, Andreas Kiesel, Peter Lootens, Heike Meyer, Michal Mos, Hilde Muylle, Chris Nunn, Mensure Özgüven, Isabel Roldán-Ruiz, Heinrich Schüle, Ivan Tarakanov, Tim van der Weijde, Moritz Wagner, Qingguo Xi, Olena Kalinina
This paper describes the complete findings of the EU-funded research project OPTIMISC, which investigated methods to optimize the production and use of miscanthus biomass. Miscanthus bioenergy and bioproduct chains were investigated by trialing 15 diverse germplasm types in a range of climatic and soil environments across central Europe, Ukraine, Russia, and China. The abiotic stress tolerances of a wider panel of 100 germplasm types to drought, salinity, and low temperatures were measured in the laboratory and a field trial in Belgium...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27916659/stronger-hypothalamus-pituitary-adrenal-axis-habituation-predicts-lesser-sensitization-of-inflammatory-response-to-repeated-acute-stress-exposures-in-healthy-young-adults
#18
Myriam V Thoma, Danielle Gianferante, Luke Hanlin, Alexander Fiksdal, Chen Xuejie, Nicolas Rohleder
Effective adjustment of the stress systems to repeated stress is regarded as an adaptive response of the organism facing environmental threats. Given the intertwined relationship between the stress systems and the inflammatory system, it could be expected that inflammatory processes should adapt to repeated stress as well. However, only little is known about adaptational processes of the different components of the immune system in response to repeated stress, and how these might be related to adaptational processes of the hypothalamus-pituitary-adrenal (HPA) axis...
December 1, 2016: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/27915159/public-speaking-avoidance-as-a-treatment-moderator-for-social-anxiety-disorder
#19
Bita Mesri, Andrea N Niles, Andre Pittig, Richard T LeBeau, Ethan Haik, Michelle G Craske
BACKGROUND AND OBJECTIVES: Cognitive behavioral therapy (CBT) and acceptance and commitment therapy (ACT) have both garnered empirical support for the effective treatment of social anxiety disorder. However, not every patient benefits equally from either treatment. Identifying moderators of treatment outcome can help to better understand which treatment is best suited for a particular patient. METHODS: Forty-nine individuals who met criteria for social anxiety disorder were assessed as part of a randomized controlled trial comparing 12 weeks of CBT and ACT...
November 23, 2016: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/27912744/quality-of-life-after-stroke-in-pakistan
#20
Wardah Khalid, Shafquat Rozi, Tazeen Saeed Ali, Iqbal Azam, Michael T Mullen, Saleem Illyas, Qamar Un-Nisa, Nabila Soomro, Ayeesha Kamran Kamal
BACKGROUND: There is very little information about the quality of life (QOL) of stroke survivors in LMIC countries with underdeveloped non communicable health infrastructures, who bear two thirds of the global stroke burden. METHODOLOGY: We used a sequential mix methods approach. First, a quantitative analytical cross-sectional study was conducted on 700 participants, who constituted 350 stroke survivor and their caregiver dyads. QOL of stroke survivor was assessed via Stroke Specific Quality of Life Scale (SSQOLS) whereas QOL of caregivers was assessed through RAND-36...
December 3, 2016: BMC Neurology
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