Du-Wen Zeng, Yong-Qiang Yang, Qi Wang, Feng-Li Zhang, Mao-Dong Zhang, Sha Liao, Zhi-Qiang Liu, Ya-Chao Fan, Chen-Guang Liu, Lin Zhang, Xin-Qing Zhao
Kluyveromyces marxianus has become an attractive non-conventional yeast cell factory due to its advantageous properties such as high thermal tolerance and rapid growth. Succinic acid (SA) is an important platform molecule that has been applied in various industries such as food, material, cosmetics, and pharmaceuticals. SA bioproduction may be compromised by its toxicity. Besides, metabolite-responsive promoters are known to be important for dynamic control of gene transcription. Therefore, studies on global gene transcription under various SA concentrations are of great importance...
April 9, 2024: Applied Microbiology and Biotechnology