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https://www.readbyqxmd.com/read/29222704/healthcare-system-barriers-to-long-term-follow-up-for-adult-survivors-of-childhood-cancer-in-british-columbia-canada-a-qualitative-study
#1
A Fuchsia Howard, Arminee Kazanjian, Sheila Pritchard, Rob Olson, Haroon Hasan, Kelly Newton, Karen Goddard
PURPOSE: Risk-stratified life-long follow-up care is recommended for adult childhood cancer survivors (CCS) to ensure appropriate prevention, screening, and management of late effects. The identification of barriers to long-term follow-up (LTFU), particularly in varying healthcare service contexts, is essential to develop and refine services that are responsive to survivor needs. We aimed to explore CCS and healthcare professionals (HCP) perspectives of healthcare system factors that function as barriers to LTFU in British Columbia, Canada...
December 8, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29222470/remote-control-of-resistive-switching-in-tio2-based-resistive-random-access-memory-device
#2
Dwipak Prasad Sahu, S Narayana Jammalamadaka
We report on the magnetic field control of a bipolar resistive switching in Ag/TiO2/FTO based resistive random access memory device through I-V characteristics. Essentially, in the presence of magnetic field and in the low resistance state, an abrupt change in the resistance of the device demands higher voltage, hinting that residual Lorentz force plays a significant role in controlling the resistance state. Endurance characteristics of the device infer that there is no degradation of the device even after repeated cycling, which ensures that the switching of resistance between 'off' and 'on' states is reproducible, reversible and controllable...
December 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29221340/sudden-hypotension-occurring-after-4-days-of-left-sided-central-catheter-placement
#3
Youn-Jung Kim, Won Young Kim
Central venous catheters (CVCs) have an important role in the management of critically ill patients. In contrast to the immediate complications after CVC insertion, the late complications were difficult to be noticed without high suspicion despite their life-threatening outcome. We report a rare but fatal delayed vascular perforation occurring after 4 days of left-sided hemodialysis catheter insertion. A 74-year-old male with septic shock was treated with continuous renal replacement therapy (CRRT) and recovered smoothly during hospitalization...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221087/scaling-the-abruptly-autofocusing-beams-in-the-direct-space
#4
Zhenyu Zhao, Chen Xie, DanDan Ni, Yuquan Zhang, Yanfeng Li, Francois Courvoisier, Minglie Hu
We propose a simple technique to scale the abruptly autofocusing beams in the direct space by introducing a scaling factor in the phase. Analytical formulas are deduced based on optical caustics, explicitly revealing how the scaling factor controls location, peak intensity, and size of the focal spot. We demonstrate that the multiplication of a scaling factor on the phase is equivalent to the axial-scaling transformation under the paraxial approximation. Further numerical and experimental results confirm theoretical predictions...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29220985/tungsten-based-highly-selective-solar-absorber-using-simple-nanodisk-array
#5
Xu Han, Kebo He, Zhubing He, Zhaoyu Zhang
In this paper, we report the design, fabrication, and characterization of a tungsten-based metamaterial selective solar absorber (SSA) combining a metal-insulator-metal (MIM) structure and simple nanodisk array. The as-fabricated absorber absorbs strongly and selectively in the wavelength range of 0.5-1.75 μm with a characterized absorptance of more than 90%, which drops abruptly to less than 12.6% beyond 2.5 μm. In addition, this broadband and highly selective absorber is polarization-insensitive under incidence of normal plane waves...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29218798/high-risk-clinical-features-for-acute-aortic-dissection-a-case-control-study
#6
Robert Ohle, Justin Um, Omar Anjum, Helena Bleeker, Lindy Luo, George Wells, Jeffrey J Perry
BACKGROUND: Acute aortic dissection (AAD) is a rare condition with a high mortality that is often missed. The objective of our study was to assess the diagnostic accuracy of clinical and laboratory findings for AAD, in confirmed cases of AAD and a low risk control group. METHODS: Historical matched case-control study: participants were adults >18 years old presenting to two tertiary care emergency departments (ED) or one regional cardiac referral center. CASES: new ED or in-hospital diagnosis of non-traumatic AAD confirmed by computed tomography or echocardiography...
December 8, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29217386/early-worsening-of-diabetic-retinopathy-after-rapid-improvement-of-blood-glucose-control-in-patients-with-diabetes
#7
REVIEW
S Feldman-Billard, É Larger, P Massin
AIM: To review the frequency, importance of and risk factors for "early worsening of diabetic retinopathy" (EWDR) after rapid improvement of blood glucose in patients with diabetes. METHODS: This was a systematic review of key references (PubMed 1980-2016) and the current international recommendations for the above-mentioned topics. RESULTS: EWDR has been described during intensive treatment (IT) in patients with uncontrolled type 1 or 2 diabetes, and after pancreas transplantation or bariatric surgery...
November 11, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29216746/employing-a-fixed-lean-multiple-schedule-in-the-treatment-of-challenging-behavior-for-children-with-autism-spectrum-disorder
#8
Shaji S Haq, Wendy Machalicek, S Andrew Garbacz, Christine Drew
Despite its utility, there is limited applied research on employing fixed-lean (FL) schedules of reinforcement in treatment packages to address challenging behavior. One potential reason is that abrupt shifts to terminal schedules of reinforcement have been associated with immediate increases in challenging behavior before subsiding to clinically acceptable levels. The purpose of the present study was to (a) provide evidence demonstrating the utility of a FL multiple schedule (MS) in the treatment of challenging behavior in applied settings, (b) examine the potential effects of alternative stimuli on challenging behavior during a FL MS, and (c) assess the social validity of this treatment package with participants and caregivers...
December 1, 2017: Behavior Modification
https://www.readbyqxmd.com/read/29214766/abrupt-increase-in-rate-of-imipenem-resistance-in-acinetobacter-baumannii-complex-strains-isolated-from-general-hospitals-in-korea-and-correlation-with-carbapenem-administration-during-2002-2013
#9
Young Ah Kim, Yoon Soo Park, Taemi Youk, Hyukmin Lee, Kyungwon Lee
No abstract text is available yet for this article.
March 2018: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/29214506/pharmacokinetics-of-oral-and-intravenous-paracetamol-acetaminophen-when-co-administered-with-intravenous-morphine-in-healthy-adult-subjects
#10
Robert B Raffa, Jayne Pawasauskas, Joseph V Pergolizzi, Luke Lu, Yin Chen, Sutan Wu, Brant Jarrett, Randi Fain, Lawrence Hill, Krishna Devarakonda
BACKGROUND AND OBJECTIVE: Several features favor paracetamol (acetaminophen) administration by the intravenous rather than the oral route in the postoperative setting. This study compared the pharmacokinetics and bioavailability of oral and intravenous paracetamol when given with or without an opioid, morphine. METHODS: In this randomized, single-blind, parallel, repeat-dose study in healthy adults, subjects received four repeat doses of oral or intravenous 1000 mg paracetamol at 6-h intervals, and morphine infusions (0...
December 6, 2017: Clinical Drug Investigation
https://www.readbyqxmd.com/read/29214085/sox5-null-heterozygous-mutation-in-a-family-with-adult-onset-hyperkinesia-and-behavioral-abnormalities
#11
Michael Zech, Katharina Poustka, Sylvia Boesch, Riccardo Berutti, Tim M Strom, Wolfgang Grisold, Werner Poewe, Juliane Winkelmann
SOX5 encodes a conserved transcription factor implicated in cell-fate decisions of the neural lineage. SOX5 haploinsufficiency induced by larger genomic deletions has been linked to a recognizable pediatric syndrome combining developmental delay with intellectual disability, mild dysmorphism, inadequate behavior, and variable additional features including motor disturbances. In contrast to SOX5-involving deletions, examples of pathogenic SOX5 small coding variations are sparse in the literature and have been described only in singular cases with phenotypic abnormalities akin to those seen in the SOX5 microdeletion syndrome...
2017: Case Reports in Genetics
https://www.readbyqxmd.com/read/29213235/changes-in-predictive-task-switching-with-age-and-with-cognitive-load
#12
Shelly Levy-Tzedek
Predictive control of movement is more efficient than feedback-based control, and is an important skill in everyday life. We tested whether the ability to predictively control movements of the upper arm is affected by age and by cognitive load. A total of 63 participants were tested in two experiments. In both experiments participants were seated, and controlled a cursor on a computer screen by flexing and extending their dominant arm. In Experiment 1, 20 young adults and 20 older adults were asked to continuously change the frequency of their horizontal arm movements, with the goal of inducing an abrupt switch between discrete movements (at low frequencies) and rhythmic movements (at high frequencies)...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29212672/cardiovascular-response-to-prescribed-detraining-among-recreational-athletes
#13
Charles Richard Pedlar, Marcel G Brown, Robert E Shave, James M Otto, Aimee Drane, Jennifer Michaud-Finch, Miranda Contursi, Meagan M Wasfy, Adolph Hutter, Michael H Picard, Gregory D Lewis, Aaron L Baggish
Exercise-induced cardiac remodeling (EICR) and the attendant myocardial adaptations characteristic of the athlete's heart may regress during periods of exercise reduction or abstinence. The time course and mechanisms underlying this reverse remodeling, specifically the impact of concomitant plasma volume (PV) contraction on cardiac chamber size, remain incompletely understood. We therefore studied recreational runners (n=21, aged 34 ± 7 years; 48% male) who completed an 18-week training program (~7 h.w-1) culminating in the 2016 Boston Marathon after which total exercise exposure was confined to <2 h...
December 6, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29211049/living-organisms-author-their-read-write-genomes-in-evolution
#14
REVIEW
James A Shapiro
Evolutionary variations generating phenotypic adaptations and novel taxa resulted from complex cellular activities altering genome content and expression: (i) Symbiogenetic cell mergers producing the mitochondrion-bearing ancestor of eukaryotes and chloroplast-bearing ancestors of photosynthetic eukaryotes; (ii) interspecific hybridizations and genome doublings generating new species and adaptive radiations of higher plants and animals; and, (iii) interspecific horizontal DNA transfer encoding virtually all of the cellular functions between organisms and their viruses in all domains of life...
December 6, 2017: Biology
https://www.readbyqxmd.com/read/29210866/abrupt-improvement-in-obsessive-compulsive-symptoms-upon-discontinuation-of-clozapine
#15
Lindsay-Rose Dykema
No abstract text is available yet for this article.
November 29, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29209584/sudden-death-from-spontaneous-coronary-artery-dissection-due-to-polyarteritis-nodosa
#16
Cyrus M Munguti, Paul M Ndunda, Tabitha M Muutu
Spontaneous coronary artery dissection (SCAD) is an emerging and rare cause of acute coronary syndrome and sudden cardiac death. While it was previously reported among young females with fibromuscular dysplasia, new literature indicates that this condition could occur in older populations. Polyarteritis nodosa (PAN) causes systemic necrotizing vasculitis which typically affects small to medium-sized muscular arteries and could affect the coronary arteries. A few case reports of PAN causing acute coronary artery disease have been reported in the literature...
October 2, 2017: Curēus
https://www.readbyqxmd.com/read/29209482/the-place-for-prophylactic-cerclage-in-the-infertile-patient-with-established-cervical-incompetence-who-conceived-twins-after-septum-reduction
#17
Jennifer Deanna, Omar Abuzied, Fahmi Islam, Ivana Vettriano, Frederico Rocha, Mostafa Abuzeid
Introduction: It is well known that cervical incompetence and associated preterm birth confers greater morbidity and mortality on birth outcomes, with an additional increased risk of cervical incompetence in higher order gestations. While the pathophysiology of cervical incompetence has yet to be elucidated, research has identified risk factors and assessed outcomes of numerous interventions. Cervical cerclage has been shown, in certain situations involving singleton pregnancies, to improve outcomes...
June 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/29205399/species-selection-under-long-term-experimental-warming-and-drought-explained-by-climatic-distributions
#18
Daijun Liu, Josep Peñuelas, Romà Ogaya, Marc Estiarte, Katja Tielbörger, Fabian Slowik, Xiaohong Yang, Mark C Bilton
Global warming and reduced precipitation may trigger large-scale species losses and vegetation shifts in ecosystems around the world. However, currently lacking are practical ways to quantify the sensitivity of species and community composition to these often-confounded climatic forces. Here we conducted long-term (16 yr) nocturnal-warming (+0.6°C) and reduced precipitation (-20% soil moisture) experiments in a Mediterranean shrubland. Climatic niche groups (CNGs) - species ranked or classified by similar temperature or precipitation distributions - informatively described community responses under experimental manipulations...
December 4, 2017: New Phytologist
https://www.readbyqxmd.com/read/29204867/talking-heads-or-talking-eyes-effects-of-head-orientation-and-sudden-onset-gaze-cues-on-attention-capture
#19
Robrecht P van der Wel, Timothy Welsh, Anne Böckler
The direction of gaze towards or away from an observer has immediate effects on attentional processing in the observer. Previous research indicates that faces with direct gaze are processed more efficiently than faces with averted gaze. We recently reported additional processing advantages for faces that suddenly adopt direct gaze (abruptly shift from averted to direct gaze) relative to static direct gaze (always in direct gaze), sudden averted gaze (abruptly shift from direct to averted gaze), and static averted gaze (always in averted gaze)...
December 4, 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/29200200/wogonin-protects-against-cisplatin-induced-acute-kidney-injury-by-targeting-ripk1-mediated-necroptosis
#20
Xiao-Ming Meng, Hai-Di Li, Wei-Feng Wu, Patrick Ming-Kuen Tang, Gui-Ling Ren, Li Gao, Xiao-Feng Li, Yang Yang, Tao Xu, Tao-Tao Ma, Zeng Li, Cheng Huang, Lei Zhang, Xiong-Wen Lv, Jun Li
Acute kidney injury (AKI), characterized by aggressive inflammatory responses and destruction of renal resident cells, can cause abrupt kidney dysfunction. To date, effective therapy for AKI is lacking. In this study, we evaluated the renoprotective effect of wogonin, an herbal active compound, using a cisplatin-induced AKI mouse model. In vivo results show that wogonin substantially suppressed the increased levels of serum creatinine and blood urea nitrogen (BUN) almost to the normal level. Wogonin also attenuated tubular damage, shown by PAS staining, electron microscopy and molecular analysis of KIM-1...
December 4, 2017: Laboratory Investigation; a Journal of Technical Methods and Pathology
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