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Fibromuscular dysplasia carotid

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https://www.readbyqxmd.com/read/28431954/isolated-intracranial-fibromuscular-dysplasia-of-the-posterior-cerebral-artery
#1
Min-Ju Yeo, Ho-Yeong Jeon, Min-Ju Cha, Hye-Yeon Jang, Sang-Gil Lee, Ji Seon Kim, Sung-Hyun Lee, Sang-Soo Lee, Dong-Ick Shin
Fibromuscular dysplasia (FMD) is a nonatherosclerotic, noninflammatory arterial disease that most commonly affects the renal and internal carotid arteries, but intracranial FMD is very rare. We report a patient with FMD involving the posterior cerebral arteries (PCAs). A 24year old female was presented with a 4day history of right homonymous hemianopsia with throbbing headache in the left temporo-occipital area. The brain magnetic resonance imaging (MRI) revealed an acute ischemic stroke in the left PCA territory, while the Time of Flight (TOF) magnetic resonance angiogram (MRA) showed segmental luminal irregularities in the left proximal PCA...
April 18, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28392116/carotid-dissection-complicated-by-polymorphic-ventricular-tachycardia
#2
Bria D Giacomino, Michael C Giudici
In this case report, we describe a patient with fibromuscular dysplasia who suffered spontaneous bilateral carotid artery dissections. This was followed by significant variations in blood pressure and heart rates during her admission. Unfortunately, during an episode of bradycardia, a premature ventricular contraction occurred during the T wave which resulted in polymorphic ventricular tachycardia. As described in the case and in graphic depiction, this hemodynamic instability resolved after stenting of the carotid artery...
April 5, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28392061/carotid-diaphragm-atypical-fibromuscular-dysplasia-or-atheromatous-lesions
#3
D Chaari, J-M Baud, L Deschamps, C Petitjean, A Maurizot, M-L Chadenat, M de Malherbe, A Jaoua, F Pico
Atypical fibromuscular dysplasia (FMD) is an underdiagnosed cause of ischemic stroke. The typical angiographic pattern of a septum on the posterolateral side of a carotid megabulb is highly suggestive of atypical FMD. We report here on two patients with this highly suggestive pattern of carotid atypical FMD, but which histological examination revealed to be atheromatous lesions. Interestingly, contrast-enhanced ultrasound of the carotid artery showed enhancement of the spur, which should never be the case with an FMD lesion, which has no vasa vasorum...
April 6, 2017: Revue Neurologique
https://www.readbyqxmd.com/read/28272662/fibromuscular-dysplasia-of-the-coronary-arteries-a-case-report-and-review-of-the-literature
#4
Julia Kuzyk, Oksana Boiko, Taras Stetsko
Fibromuscular dysplasia is a nonatherosclerotic and non-inflammatory vascular disease with primary lesion of renal and internal carotid arteries. We present a neonatal case of fibromuscular dysplasia who died on the second day of life. The newborn suffered from fibromuscular dysplasia of the coronary arteries and a congenital heart defect. The interesting feature of this case was the formation of aneurysms of the coronary arteries with pulmonary atresia. This case demonstrates a casuistically rare form of association between fibromuscular dysplasia of the coronary arteries and pulmonary artery atresia...
February 4, 2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28264182/endarterectomy-for-a-symptomatic-carotid-web
#5
John Phair, Eric B Trestman, Chetra Yean, Evan C Lipsitz
Background We report a symptomatic carotid web successfully treated with carotid endarterectomy. A healthy 43-year-old woman presented with acute-onset left-sided weakness. Carotid web was evident on computed tomography angiography as a focal filling defect in the right common carotid artery. This right common carotid artery web extended into the ICA created an eddy resulting in turbulent flow. Subsequent acute embolus formation led to embolization and acute stroke. Method Review of the literature was performed using Medline Plus and PubMed databases...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28157058/fibromuscular-dysplasia-results-of-a-multicentre-study-in-flanders
#6
Marie De Groote, Patricia Van der Niepen, Dimitri Hemelsoet, Bert Callewaert, Frank Vermassen, Jean-Marie Billiouw, An De Vriese, Jan Donck, Tine De Backer
BACKGROUND: Fibromuscular dysplasia (FMD) is an idiopathic, non-inflammatory, non-atherosclerotic vascular disease, resulting in focal narrowing of small and medium-sized arteries. Systematic recording of clinical data in central databases as in the US and France provided new insights into FMD. The main objectives of this multicentre study were to explore the epidemiology, pattern of vascular involvement, clinical manifestations, and management of FMD patients in Flanders. PATIENTS AND METHODS: Multicentre, retrospective registry of patients diagnosed with FMD based on medical imaging...
February 3, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28056533/hemicrania-continua-in-carotid-artery-dissection-symptomatic-cases-or-linked-pathophysiology
#7
Roland Brilla, Matthias Pawlowski, Stefan Evers
Background Hemicrania continua (HC) -like headaches have been rarely reported as symptomatic headaches, including cases secondary to cervical artery dissection. Case series We present five cases of HC-like headaches following cervical artery dissection, in three cases with specific indomethacin response. In two cases, comorbidity of fibromuscular dysplasia (FMD) was noted. Conclusion Carotid artery dissection may result in an HC-like headache syndrome. A specific response to indomethacin does not rule out dissection as underlying pathology...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28042220/internal-carotid-artery-fibromuscular-dysplasia-in-a-child-incidental-postmortem-finding-after-head-injury
#8
Arulselvi Subramanian, Garima Aggarwal, Deepak Agarwal, Sanjeev Lalwani
Fibromuscular dysplasia (FMD) is a rare, segmental, nonatheromatous, and noninflammatory arterial disease of unknown etiology. It predominantly involves renal artery (60-75%) followed by extracranial part of the internal carotid artery and vertebral arteries (25-30%). The disease typically affects middle-aged women and involves intermediate-sized arteries throughout the body. There are rare case reports of extracranial FMD compounding a trauma case. A patient was brought to trauma center emergency with a history of fall from height...
January 2017: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/28006960/lower-extremity-fibromuscular-dysplasia
#9
Ellen Brinza, Victoria Grabinski, Sridevi Durga, Sarah O'Connor, Sandra L Yesenko, Esther S H Kim, Heather L Gornik
Fibromuscular dysplasia (FMD), a disease well described in the renal and cerebrovascular circulations, also manifests in the lower extremity (LE) arteries. This study reports on the clinical presentation, imaging findings, and treatment of patients with LE FMD seen at a single center. Over a 7-year span, 100 of 449 patients with FMD had imaging of the LE arteries, of which 62 were found to have LE FMD (13.8% of the entire FMD cohort including patients with and without LE imaging). The majority of patients were women (96...
January 1, 2016: Angiology
https://www.readbyqxmd.com/read/27854110/association-between-carotid-artery-tortuosity-and-carotid-dissection-a-case-control-study
#10
Sarasa T Kim, Waleed Brinjikji, Vance T Lehman, Carrie M Carr, Patrick H Luetmer, Charlotte H Rydberg
BACKGROUND: Carotid artery dissections have long been associated with compromise of the structural integrity of the arterial wall from heritable connective-tissue disorders, hypertension, and trauma. However, an association between spontaneous internal carotid artery dissection and tortuous or redundant carotid anatomy has not been fully explored. METHODS: Patients with CTA confirmed spontaneous cervical internal carotid artery dissections were compared to a group of age and sex matched controls who also received CTA of the neck...
November 17, 2016: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27827286/-hypertension-due-to-fibromuscular-dysplasia-look-for-additional-disease-sites
#11
M L Maas, J M Kroese, S J H Bredie, C T Postma, F E de Leeuw, L J Schultze Kool, N P Riksen
Fibromuscular dysplasia (FMD) is a non-inflammatory, non-atherosclerotic vasculopathy that can lead to arterial stenosis, occlusion, aneurysms, and dissection. FMD of the renal arteries can lead to renovascular hypertension. Percutaneous angioplasty of the renal arteries (PTRA) can lead to normalization of blood pressure in 45% of patients with renal artery stenosis caused by FMD, particularly in younger patients and patients with a short history of hypertension. A considerable number of the patients with renovascular FMD also have cervical FMD, which can lead to ischaemic or haemorrhagic stroke...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27792790/phactr1-is-a-genetic-susceptibility-locus-for-fibromuscular-dysplasia-supporting-its-complex-genetic-pattern-of-inheritance
#12
Soto Romuald Kiando, Nathan R Tucker, Luis-Jaime Castro-Vega, Alexander Katz, Valentina D'Escamard, Cyrielle Tréard, Daniel Fraher, Juliette Albuisson, Daniella Kadian-Dodov, Zi Ye, Erin Austin, Min-Lee Yang, Kristina Hunker, Cristina Barlassina, Daniele Cusi, Pilar Galan, Jean-Philippe Empana, Xavier Jouven, Anne-Paule Gimenez-Roqueplo, Patrick Bruneval, Esther Soo Hyun Kim, Jeffrey W Olin, Heather L Gornik, Michel Azizi, Pierre-François Plouin, Patrick T Ellinor, Iftikhar J Kullo, David J Milan, Santhi K Ganesh, Pierre Boutouyrie, Jason C Kovacic, Xavier Jeunemaitre, Nabila Bouatia-Naji
Fibromuscular dysplasia (FMD) is a nonatherosclerotic vascular disease leading to stenosis, dissection and aneurysm affecting mainly the renal and cerebrovascular arteries. FMD is often an underdiagnosed cause of hypertension and stroke, has higher prevalence in females (~80%) but its pathophysiology is unclear. We analyzed ~26K common variants (MAF>0.05) generated by exome-chip arrays in 249 FMD patients and 689 controls. We replicated 13 loci (P<10-4) in 402 cases and 2,537 controls and confirmed an association between FMD and a variant in the phosphatase and actin regulator 1 gene (PHACTR1)...
October 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27790125/a-case-of-turner-syndrome-with-multiple-embolic-infarcts
#13
Cindy W Yoon, Eungseok Lee, Byung-Nam Yoon, Hee-Kwon Park, Joung-Ho Rha
Only a few cases of Turner syndrome (TS) with ischemic stroke have been reported. Various arteriopathies of the cerebral arteries, including fibromuscular dysplasia, congenital hypoplasia, moyamoya syndrome, and premature atherosclerosis have been assumed to be the cause of ischemic stroke in TS. There has been no case report of a TS patient presenting with an embolic stroke pattern without any cerebral arteriopathy. A 28-year-old woman with TS was referred to our hospital because of abnormal brain magnetic resonance imaging (MRI) findings...
September 2016: Case Reports in Neurology
https://www.readbyqxmd.com/read/27781048/internal-carotid-artery-s-shaped-curve-as-a-marker-of-fibromuscular-dysplasia-in-dissection-related-acute-ischemic-stroke
#14
Diogo C Haussen, Ashutosh Jadhav, Leticia C Rebello, Samir Belagaje, Aaron Anderson, Tudor Jovin, Amin Aghaebrahim, Deepak Gulati, Bryan Wells, Michael Frankel, Raul G Nogueira
BACKGROUND AND PURPOSE: Craniocervical fibromuscular dysplasia (FMD) is associated with dissections and with S-shaped curves in the internal carotid artery (ICA). We evaluated the occurrence of S-curves in patients presenting with acute strokes due to ICA steno-occlusive dissections. METHODS: This was a retrospective review of the interventional databases of two academic tertiary-care institutions. The presence of ICA S-shaped curves, C-shaped curves, 360-degree loops, as well as classic FMD and atherosclerotic changes at the ICA bulb and curve/loop was determined...
September 2016: Interventional Neurology
https://www.readbyqxmd.com/read/27512536/endovascular-treatment-of-renal-artery-stenosis-due-to-fibromuscular-dysplasia-is-stent-implantation-underused-in-this-circumstance
#15
Efe Edem, Murat Necati Aksoy, Mustafa Türker Pabuccu, Ersan Tatlı
Fibromuscular dysplasia (FMD) is a nonatherosclerotic and noninflammatory arterial disease that commonly affects the renal and carotid arteries. The primary target in treating patients with renal artery FMD is the control of blood pressure in order to prevent end-organ damage, which can be caused by poorly controlled hypertension. Invasive endovascular treatment should be taken into consideration both when hypertension cannot be controlled with medication. According to current opinion, hypertension attributed to renal artery FMD is often successfully treated solely with percutaneous renal balloon angioplasty (PRBA), with no requirement for stent implantation under most circumstances...
April 2016: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/27508836/-op-7c-04-genetic-association-study-identifies-common-variation-in-phactr1-to-associate-with-fibromuscular-dysplasia
#16
S Kiando, N Tucker, L Castro-Vega, D Cusi, P Galan, Empana J-P, J Olin, H Gornik, P-F Plouin, I Kullo, D Milan, S Ganesh, P Boutouyrie, J Kovacic, X Jeunemaitre, N Bouatia-Naji
OBJECTIVE: Fibromuscular dysplasia (FMD) is a nonatherosclerotic vascular disease leading to stenosis, dissection and aneurysm affecting mainly the renal and cerebrovascular arteries. FMD has higher prevalence in females (80-90%) and predisposes to hypertension and stroke but its pathophysiology is unclear. DESIGN AND METHOD: We performed a multistage genetic association study (1,154 patients and 3,895 controls) from five case-control cohorts. We investigated the association between rs9349379 in the phosphatase and actin regulator 1 gene (PHACTR1) and carotid traits by echo-tracking in healthy volunteers, the expression of PHACTR1 by genotypes in human fibroblasts, protein staining pattern in human carotids, and vasculature development after Phactr1 knockdown in zebrafish...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27508830/-op-1c-05-the-polish-registry-for-fibromuscular-dysplasia-the-preliminary-report-on-distribution-of-vascular-bed-involvement-and-complications-in-patients-enrolled-in-arcadia-pol-study
#17
E Warchol-Celinska, K Hanus, P Talarowska, E Florczak, K Jozwik-Plebanek, M Januszewicz, I Michalowska, A Prejbisz, W Wojcik, H Janaszek-Sitkowska, M Makowiecka-Ciesla, L Stryczynski, M Protasiewicz, L Swiatlowski, A Niemirska, M Litwitn, T Przewlocki, M Szczerbo-Trojanowska, A Tykarski, A Januszewicz
OBJECTIVE: To present preliminary evaluation of vascular bed involvement and vascular complications in patients with fibromuscular dysplasia (FMD) enrolled to ARCADIA-POL registry. DESIGN AND METHOD: The first 84 patients (59F[70.2%], 25M[29.8%], mean age: 42.5 ± 14.8 years, range:18-72) with confirmed FMD in any vascular bed were enrolled in 2015 in ARCADIA-POL registry (instituted on the basis of as Polish-French collaboration). A standardized FMD data form was used for data collection...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27508805/-op-1c-04-structural-and-functional-arterial-abnormalities-in-fibromuscular-dysplasia-are-in-the-continuum-of-hypertension-an-imaging-and-biomechanical-study
#18
L Marais, P Boutouyrie, H Khettab, C Boulanger, A Lorthiroir, M Frank, R Niarra, J Renard, Y Chambon, X Jeunemaitre, M Zidi, P-F Plouin, S Laurent, M Azizi
OBJECTIVE: Fibromuscular dysplasia (FMD) is a non-atherosclerotic non-inflammatory arterial disease, which occurs mostly in middle-aged women and affects medium-sized arteries. We previously showed abnormalities within common carotid artery (CCA) wall, with the presence of triple signal (TS) at ultrasound suggesting the presence of supplementary layers. We aimed at coupling TS presence with microconstituents of the vessel wall, derived from fitting of the pressure-diameter curve. DESIGN AND METHOD: We included 50 non-smoking patients with multifocal FMD, 50 essential hypertensive (EH) patients and 50 healthy subjects (HS) matched for age, sex, ethnicity and BP (EH and FD)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27508731/-op-5a-04-evaluation-of-retinal-microperfusion-and-arteriolar-structure-in-patients-with-fibromuscular-dysplasia-the-preliminary-data-of-the-polish-registry-for-fibromuscular-dysplasia
#19
E Warchol-Celinska, M Gosk-Przybylek, J Harazny, E Binczyk, K Szymanek, K Hanus, K Jozwik-Plebanek, E Florczak, A Prejbisz, I Cendrowska-Demkow, P Dobrowolski, A Klisiewicz, I Kurkowska-Jastrzebska, B Blazejewska-Hyzorek, M Januszewicz, I Michalowska, J P Szaflik, R E Schmieder, J Szaflik, A Januszewicz
OBJECTIVE: To compare retinal microperfusion and arteriolal structure between patients with fibromuscular dysplasia (FMD) enrolled to the ARCADIA-POL registry and patients with essential hypertension (EHT). DESIGN AND METHOD: From the first 84 patients with confirmed FMD in any vascular bed enrolled in the ARCADIA-POL registry in 2015 (instituted on the basis of as Polish-French collaboration), we analyzed data regarding retinal microperfusion and arteriolar structure available from 70 patients (51F, 19 M, mean age: 41...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27504335/resistant-hypertension-due-to-fibromuscular-dysplasia-in-a-young-male-a-rare-case-report
#20
Hossein Vakili, Isa Khaheshi, Mehdi Memaryan, Roxana Sadeghi, Mohammadreza Naderian
Fibromuscular Dysplasia (FMD) is a sporadic non-atherosclerotic disease. FMD has been established in nearly every arterial bed. However, the most frequent arteries affected are the renal and carotid arteries. Disease presentation may vary broadly, depending upon the arterial bed complication and the severity of illness. Hypertension, particularly resistant type, headache and dizziness are the most common presentations. String of beads appearance in angiographic views due to post-stenotic aneurysms is the characteristic view...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
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