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https://www.readbyqxmd.com/read/28220602/mexametric-and-cutometric-assessment-of-the-signs-of-aging-of-the-skin-area-around-the-eyes-after-the-use-of-non-ablative-fractional-laser-non-ablative-radiofrequency-and-intense-pulsed-light
#1
Anna Maria Kołodziejczak, Helena Rotsztejn
The assessment of the signs of aging within eyes area in cutometric (skin elasticity) and mexametric (discoloration and severity of erythema) examination after the treatment with: non-ablative fractional laser, non-ablative radiofrequency (RF) and intense light source (IPL). This study included 71 patients, aged 33-63 years (the average age was 45.81) with Fitzpatrick skin type II and III. 24 patients received 5 successive treatment sessions with a 1,410-nm non-ablative fractional laser in two-week intervals, 23 patients received 5 successive treatment sessions with a non-ablative RF in one-week intervals and 24 patients received 5 successive treatment sessions with an IPL in two-week intervals...
February 21, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28206829/validity-of-low-contrast-letter-acuity-as-a-visual-performance-outcome-measure-for-multiple-sclerosis
#2
Laura J Balcer, Jenelle Raynowska, Rachel Nolan, Steven L Galetta, Raju Kapoor, Ralph Benedict, Glenn Phillips, Nicholas LaRocca, Lynn Hudson, Richard Rudick
Low-contrast letter acuity (LCLA) has emerged as the leading outcome measure to assess visual disability in multiple sclerosis (MS) research. As visual dysfunction is one of the most common manifestations of MS, sensitive visual outcome measures are important in examining the effect of treatment. Low-contrast acuity captures visual loss not seen in high-contrast visual acuity (HCVA) measurements. These issues are addressed by the MS Outcome Assessments Consortium (MSOAC), including representatives from advocacy organizations, Food and Drug Administration (FDA), European Medicines Agency (EMA), National Institute of Neurological Disorders and Stroke (NINDS), academic institutions, and industry partners along with persons living with MS...
February 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28164458/comparison-of-hair-removal-efficacy-and-side-effect-of-neodymium-yttrium-aluminum-garnet-laser-and-intense-pulsed-light-systems-18-month-follow-up
#3
Georgina Zita Szima, Eszter Anna Janka, Anikó Kovács, Blanka Bortély, Edina Bodnár, Irina Sawhney, Éva Szabó, Éva Remenyik
BACKGROUND: Photothermal destruction of hair shaft melanin with intense pulsed light (IPL) and neodymium:yttrium-aluminum-garnet (Nd:YAG) laser has become an effective treatment of hair removal. AIMS: Our aim was to compare efficacy, satisfactory levels, safety, and side effects of Nd:YAG and IPL in hair reduction. METHODS: This was a prospective randomized intrapatient, right-left, assessor-blinded comparison of Nd:YAG vs IPL. There were 38 volunteers recruited...
February 6, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28135360/retinal-architecture-and-melanopsin-mediated-pupillary-response-characteristics-a-putative-pathophysiologic-signature-for-the-retino-hypothalamic-tract-in-multiple-sclerosis
#4
Ethan Meltzer, Peter V Sguigna, Adnan Subei, Shin Beh, Eric Kildebeck, Darrel Conger, Amy Conger, Marlen Lucero, Benjamin S Frohman, Ashley N Frohman, Shiv Saidha, Steven Galetta, Peter A Calabresi, Robert Rennaker, Teresa C Frohman, Randy H Kardon, Laura J Balcer, Elliot M Frohman
Importance: A neurophysiologic signature of the melanopsin-mediated persistent constriction phase of the pupillary light reflex may represent a surrogate biomarker for the integrity of the retinohypothalamic tract, with potential utility for investigating alterations in homeostatic mechanisms associated with brain disorders and implications for identifying new treatments. Objective: To characterize abnormalities of retinal architecture in patients with multiple sclerosis (MS) and corresponding alterations in the melanopsin-mediated sustained pupillary constriction response...
January 30, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28059657/language-outcomes-after-resection-of-dominant-inferior-parietal-lobule-gliomas
#5
Derek G Southwell, Marco Riva, Kesshi Jordan, Eduardo Caverzasi, Jing Li, David W Perry, Roland G Henry, Mitchel S Berger
OBJECTIVE The dominant inferior parietal lobule (IPL) contains cortical and subcortical regions essential for language. Although resection of IPL tumors could result in language deficits, little is known about the likelihood of postoperative language morbidity or the risk factors predisposing to this outcome. METHODS The authors retrospectively examined a series of patients who underwent resections of gliomas from the dominant IPL. Postoperative language outcomes were characterized across the patient population...
January 6, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27994506/distributed-features-of-vimentin-containing-neural-precursor-cells-in-olfactory-bulb-of-sod1g93a-transgenic-mice-a-study-about-resource-of-endogenous-neural-stem-cells
#6
Chunyan Tang, Lei Zhu, Weiming Gan, Huiting Liang, Jiao Li, Jie Zhang, Xiong Zhang, Yi Lu, Renshi Xu
No any effective treatments can prevent from the motor neuron degeneration in amyotrophic lateral sclerosis (ALS) at present. In order to modulating the endogenous neural precursor cells (NPCs) to repairing the degenerative motor neurons in ALS, we studied the alteration of endogenous vimentin-containing NPCs in olfactory bulb (OB) at the different stages of SOD1 wlid-type and G93A transgenic mice. The results showed that the vimentin-containing cells (VCCs) were mainly distributed in the glomerular layer (Gl), the accessory OB (AOB), the OB core, the granular cell layer (GRO) and the mitral cell layer (MI)+the internal plexiform layer (IPL) of the OB of adult mice...
2016: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/27911118/effects-of-intense-pulsed-light-in-microstomia-in-patients-with-systemic-sclerosis-a-pilot-study
#7
Lisbeth Rosholm Comstedt, Åke Svensson, Roger Hesselstrand, Leena Lehti, Agneta Troilius Rubin
INTRODUCTION: The effects of IPL on collagen structures is well known in the treatment of photo damaged skin. OBJECTIVE: To investigate the effect of IPL on sclerotic skin by treating patients with microstomia due to systemic sclerosis. METHOD AND MATERIAL: 13 patients all with microstomia and systemic sclerosis was treated with IPL PR/VL applicator. They were treated in the perioral area 8 times with 3-4 weeks' interval and follow-up for 6 months...
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27911117/are-lasers-superior-to-lights-in-the-photoepilation-of-fitzpatrick-v-and-vi-skin-types-a-comparison-between-nd-yag-laser-and-intense-pulsed-light
#8
Bibilash Bs, Ravi Kumar Chittoria, Devinder Mohan Thappa, Devi Prasad Mohapatra, Friji M T, Dineshkumar S, Sandhya Pandey
BACKGROUND AND OBJECTIVES: There are no large volume comparative studies available to compare the efficacy of lasers over lights for hair removal in Fitzpatrick V and VI skin types. This study is designed to compare the efficacy of Nd:YAG Laser versus IPL in the darker skin types. STUDY DESIGN/MATERIALS AND METHODS: Thirty nine patients included in Group-1 were treated with Nd:YAG and 31 in group-2 with IPL. Both groups received 5 sessions of treatment. The hair counts were assessed using digital photography and manual counting method before and after treatment and results were analysed...
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27904270/morphologic-changes-of-zebrafish-melanophore-after-intense-pulsed-light-and-q-switched-nd-yag-laser-irradiation
#9
Hwa Jung Ryu, Ji Min Lee, Hee Won Jang, Hae Chul Park, Im Joo Rhyu, Il-Hwan Kim
BACKGROUND: Recently, the pulse-in-pulse mode of intense pulsed light (IPL) has been used increasingly for the treatment of melasma. OBJECTIVE: To observe the morphologic changes in the melanophore in adult zebrafish after irradiation with conventional and pulse-in-pulse IPL and Q-switched Nd:YAG (QSNY) laser. METHODS: Adult zebrafish were irradiated with conventional and pulse-in-pulse mode of IPL. The conditions for conventional IPL were 3 mJ/cm(2), 560 nm filter, and pulse widths of 7, 20, and 35 msec...
December 2016: Annals of Dermatology
https://www.readbyqxmd.com/read/27894158/craving-behavioral-intervention-for-internet-gaming-disorder-remediation-of-functional-connectivity-of-the-ventral-striatum
#10
Jin-Tao Zhang, Shan-Shan Ma, Chiang-Shan R Li, Lu Liu, Cui-Cui Xia, Jing Lan, Ling-Jiao Wang, Ben Liu, Yuan-Wei Yao, Xiao-Yi Fang
Psychobehavioral intervention is an effective treatment of Internet addiction, including Internet gaming disorder (IGD). However, the neural mechanisms underlying its efficacy remain unclear. Cortical-ventral striatum (VS) circuitry is a common target of psychobehavioral interventions in drug addiction, and cortical-VS dysfunction has been reported in IGD; hence, the primary aim of the study was to investigate how the VS circuitry responds to psychobehavioral interventions in IGD. In a cross-sectional study, we examined resting-state functional connectivity of the VS in 74 IGD subjects (IGDs) and 41 healthy controls (HCs)...
November 28, 2016: Addiction Biology
https://www.readbyqxmd.com/read/27887859/olanzapine-modulation-of-long-and-short-range-functional-connectivity-in-the-resting-brain-in-a-sample-of-patients-with-schizophrenia
#11
Wenbin Guo, Feng Liu, Jindong Chen, Renrong Wu, Lehua Li, Zhikun Zhang, Jingping Zhao
Treatment effects of antipsychotic drugs on cerebral function are seldom examined. Exploring functional connectivity (FC) in drug-free schizophrenia patients before and after antipsychotic treatment can improve the understanding of antipsychotic drug mechanisms. A total of 17 drug-free patients with recurrent schizophrenia and 24 healthy controls underwent resting-state functional magnetic resonance imaging scans. Long- and short-range FC strengths (FCS) were calculated for each participant. Compared with the controls, the patients at baseline exhibited increased long-range positive FCS (lpFCS) in the bilateral inferior parietal lobule (IPL) and decreased lpFCS in the brain regions of the default-mode network (DMN) regions and sensorimotor circuits of the brain...
November 22, 2016: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27877046/comparative-effect-and-safety-of-verapamil-in-keloid-and-hypertrophic-scar-treatment-a-meta-analysis
#12
Zhouna Li, Zhehu Jin
BACKGROUND: Keloids and hypertrophic scars are the most common types of pathological scarring. Traditionally, keloids have been considered as a result of aberrant wound healing, involving excessive fibroblast participation that is characterized by hyalinized collagen bundles. However, the usefulness of this characterization has been questioned. In recent years, studies have reported the appropriate use of verapamil for keloids and hypertrophic scars. METHODS: Searches were conducted on the databases Medline, Embase, Cochrane, PubMed, and China National Knowledge Infrastructure from 2006 to July 2016...
2016: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/27869377/physical-modalities-for-the-treatment-of-rosacea
#13
Maja A Hofmann, Percy Lehmann
Rosacea is characterised by a wide variety of vascular changes. Apart from telangiectasia and erythema, often so-called flushing occurs. These vascular abnormalities can be targeted with specific light and laser devices. In addition to KTP laser, pulsed dye laser (PDL) and Nd:YAG laser, also intense pulsed light devices (IPLs) are used. The described therapeutic effects include the reduction of vascular abnormalities and even improvement of papulopustular changes. While the KTP laser shows very good results in telangiectasia, the dye laser and IPL devices are used preferably in erythema...
December 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/27855985/can-time-averaged-flow-boundary-conditions-be-used-to-meet-the-clinical-timeline-for-fontan-surgical-planning
#14
Zhenglun Alan Wei, Phillip M Trusty, Mike Tree, Christopher M Haggerty, Elaine Tang, Mark Fogel, Ajit P Yoganathan
Cardiovascular simulations have great potential as a clinical tool for planning and evaluating patient-specific treatment strategies for those suffering from congenital heart diseases, specifically Fontan patients. However, several bottlenecks have delayed wider deployment of the simulations for clinical use; the main obstacle is simulation cost. Currently, time-averaged clinical flow measurements are utilized as numerical boundary conditions (BCs) in order to reduce the computational power and time needed to offer surgical planning within a clinical time frame...
January 4, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/27853342/theoretical-review-of-the-treatment-of-pigmented-lesions-in-asian-skin
#15
Taro Kono, Samantha Y Shek, Henry H L Chan, William F Groff, Kotaro Imagawa, Tadashi Akamatsu
Asian skin has a higher epidermal melanin content, making it more likely to develop adverse pigmentary reactions following laser surgery. The nanosecond lasers are the gold standard for the treatment of pigmented lesions, but the risk of complications, such as post-inflammatory hyperpigmentation, is increased in dark-skinned patients. Intense Pulsed Light (IPL) or long-pulsed lasers are available for treating superficial pigmented lesions, and fewer complications are seen when using these devices compared to the nanosecond lasers...
October 1, 2016: Laser Therapy
https://www.readbyqxmd.com/read/27834464/are-there-any-changes-in-posterior-ocular-structure-parameters-in-pediatric-migraine-patients
#16
Pinar Nalcacioglu, Ayse G Taslipinar Uzel, Mehmet M Uzel, Nurullah Cagil, Aysegul N Citak Kurt
PURPOSE: To evaluate the thickness of the peripapillary retinal nerve fiber layer (RNFL), total macula, macular ganglion cell layer (GCL), inner plexiform layer (IPL), and choroid in pediatric migraine patients and compare the values with healthy subjects. METHODS: This observational and cross-sectional study included 40 patients in the migraine group and 40 healthy control subjects. The thickness of the peripapillary RNFL, total macula, GCL, and IPL was analyzed with spectral-domain optic coherence tomography, while choroidal thickness was analyzed with the enhanced depth imaging protocol...
November 10, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/27812490/comparing-two-methods-of-cryotherapy-and-intense-pulsed-light-with-triamcinolone-injection-in-the-treatment-of-keloid-and-hypertrophic-scars-a-clinical-trial
#17
Simin Shamsi Meymandi, Mahmood Moosazadeh, Azadeh Rezazadeh
OBJECTIVES: Keloid and hypertrophic scars are abnormal manifestations of wounds that occur following skin injuries in the form of local proliferation of fibroblasts and increased production of collagen. There are several ways to cure these scars; treatment must be selected based on the nature of the scars. In this clinical trial, two methods-cryotherapy and intense pulsed light (IPL)-are compared in the treatment of scars, and the results are presented in terms of improvement level, complications, and patient satisfaction...
October 2016: Osong Public Health and Research Perspectives
https://www.readbyqxmd.com/read/27762643/intense-pulsed-light-ipl-treatment-for-the-skin-in-the-eye-area-clinical-and-cutometric-analysis
#18
Anna Augustyniak, Helena Rotsztejn
OBJECTIVE: The aim of the research was to establish the influence of IPL treatment on skin ageing in the eye area. MATERIAL AND METHODS: This study included 24 women, aged 38-63 years (mean age was 48.04) with Fitzpatrick skin type II and III who underwent five successive treatment sessions with an IPL in two-week intervals. The Cutometer (Courage + Khazaka electronic) reference test was an objective method for the assessment of the biomechanical properties of the skin...
February 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27697004/intense-pulsed-light-from-the-past-to-the-future
#19
Dan Li, Shi-Bin Lin, Biao Cheng
BACKGROUND: For 20 years, intense pulsed light (IPL) technology has been used to treat various medical problems. IPL has since developed rapidly, becoming popular among patients worldwide. Recently, IPL has been used mainly for cosmetic purposes. Researchers are constantly seeking new applications of IPL to meet the increasing needs of patients. OBJECTIVE: This review summarizes the development of IPL devices, discusses the current literature on the clinical application of IPL to increase our understanding of IPL, and provides guidance for broadening its clinical applications...
October 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27688446/efficacy-of-intense-pulsed-light-therapy-in-the-treatment-of-facial-acne-vulgaris-comparison-of-two-different-fluences
#20
Monika V Patidar, Ashish Ramchandra Deshmukh, Maruti Yadav Khedkar
BACKGROUND: Acne vulgaris is the most common disease of the skin affecting adolescents and young adults causing psychological distress. The combination of antibiotic resistance, adverse effects of topical and systemic anti acne medications and desire for high tech approaches have all led to new enthusiasm for light based acne treatment. Intense pulse light (IPL) therapy has three modes of action in acne vulgaris i.e., photochemical, photo thermal and photo immunological. AIMS: (1) to study efficacy of IPL therapy in facial acne vulgaris...
September 2016: Indian Journal of Dermatology
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