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https://www.readbyqxmd.com/read/29154961/inhibition-of-cyclooxygenase-cox-2-suppresses-the-recruitment-of-endothelial-progenitor-cells-in-the-microvasculature-of-endometriotic-lesions
#1
Jeannette Rudzitis-Auth, Ruth M Nickels, Michael D Menger, Matthias W Laschke
The incorporation of endothelial progenitor cells (EPCs) into newly developing blood vessels contributes to the vascularization of endometriotic lesions. here, we analyzed whether cyclooxygenase (COX)-2 signaling regulates this vasculogenic process. Endometriotic lesions were surgically induced in irradiated FVB/N mice, which were reconstituted with bone marrow from FVB/N-TgN (Tie2/green fluorescent protein (GFP)) 287 Sato mice. The animals received β-estradiol 17-valerate once a week and were daily treated with the selective COX-2 inhibitor parecoxib (25 mg/kg) or vehicle (control) over 7 and 28 days...
November 15, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/29154247/diagnostic-evaluation-of-neck-torsion-test-in-objective-examination-in-patients-with-vertigo-and-or-hearing-impairment
#2
Piotr Niewiadomski, Marzena Bielińska, Piotr Pietkiewicz, Jurek Olszewski
INTRODUCTION: The aim of the study was to evaluate the neck torsion test in objective examinations of patients with vertigo and/or hearing loss. MATERIAL AND METHODS: The study was conducted in 100 patients, including 54 women and 46 men aged 17-79 years, who were divided into two groups: I - 50 patients, including 30 women and 20 men aged 17-79 years (mean age 49.92 years) with dizziness and/or hearing impairments, and confirmed asymmetry of intracranial vessels, II - 50 patients - the control group, including 24 women and 26 men aged 20-71 years without dizziness and/or hearing disorders and without disturbance in the construction of intracranial vessels...
October 30, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/29153914/determination-of-orientin-in-trollius-chinensis-using-ultrasound-assisted-extraction-and-high-performance-liquid-chromatography-several-often-overlooked-sample-preparation-parameters-in-an-ultrasonic-bath
#3
Mengxia Wei, Lei Yang
The erratic pressure intensities and cavitation exhibited in an ultrasonic bath pose various during practical application. To achieve the most efficient experimental design, this manuscript aims to discover violently sites that are subject to the effect of slight changes in position on cavitation and ultrasound intensity distributed in the ultrasonic bath. In addition, optimization several often over-looked ultrasound parameters and experimental conditions, are intended to place the reaction vessel properly and operate under suitable experimental conditions to obtain the maximum yield of target analyte...
November 15, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29150365/correlation-between-ultrasound-appearance-of-small-breast-cancer-and-axillary-lymph-node-metastasis
#4
Xiaoqin Yu, Xiaoyan Hao, Jing Wan, Yingying Wang, Lan Yu, Binyue Liu
To study the correlation of ultrasonographic signs of small breast cancer (maximum diameter ≤2.0 cm) with axillary lymph node metastasis, pre-operative ultrasonographic images of 153 small breast malignant neoplasms in 143 breast cancer patients were analyzed according to their pathologic features. Of the small breast tumors included, 47 showed axillary lymph node metastasis. Diagnosis of all patients was obtained with radical axillary surgery or a sentinel lymph node biopsy procedure. Ultrasonographic signs included irregular shape, microlobulated contour, spiculation, microcalcification, posterior echo attenuation, blood-flow grade, perforating vessels, changes in fascia or cooper's ligament and maximum cortical thickness of lymph nodes...
November 14, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29143321/interobserver-agreement-on-standardized-ultrasound-and-histopathologic-signs-for-the-prenatal-diagnosis-of-placenta-accreta-spectrum-disorder
#5
Nurit Zosmer, Eric Jauniaux, Catey Bunce, Jenie Panaiotova, Hizbullah Shaikh, Kypros H Nicholaides
OBJECTIVE: To evaluate interobserver agreement in assessment of ultrasound signs and histopathologic findings associated with placenta accreta spectrum (PAS) disorders. METHODS: A retrospective study was conducted using data for patients prenatally diagnosed with PAS disorders at a UK hospital between January 31, 2012, and March 30, 2017. Ultrasound images (including gray-scale and color Doppler imaging [CDI] parameters) and histopathologic slides were reviewed by two observers; the level of agreement was calculated...
November 16, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29142842/prevention-and-management-of-bleeding-in-thyroid-surgery
#6
REVIEW
Gabriele Materazzi, Carlo Enrico Ambrosini, Lorenzo Fregoli, Luigi De Napoli, Gianluca Frustaci, Valeria Matteucci, Piermarco Papini, Sohail Bakkar, Paolo Miccoli
Post-thyroidectomy neck hematoma represents a major concern for surgeons because it can result in severe and even life-threatening complications. In fact, postoperative hemorrhage may result in airway compression and respiratory distress, and therefore, effective hemostasis is an important goal in thyroid surgery. Postoperative hematoma occurs at a rate of approximately 0.1% to 1.1%. Almost all cases occur in the first 6 h after surgery and can be the result of several surgeon or patient factors. For many years the clamp-and-tie technique has been the most common way to divide the main vascular pedicles of the thyroid gland...
October 2017: Gland Surgery
https://www.readbyqxmd.com/read/29141114/ph-ultrasound-dual-responsive-gas-generator-for-ultrasound-imaging-guided-therapeutic-inertial-cavitation-and-sonodynamic-therapy
#7
Qianhua Feng, Wanxia Zhang, Xuemei Yang, Yuzhen Li, Yongwei Hao, Hongling Zhang, Lin Hou, Zhenzhong Zhang
Herein, a pH/ultrasound dual-responsive gas generator is reported, which is based on mesoporous calcium carbonate (MCC) nanoparticles by loading sonosensitizer (hematoporphyrin monomethyl ether (HMME)) and modifying surface hyaluronic acid (HA). After pinpointing tumor regions with prominent targeting efficiency, HMME/MCC-HA decomposes instantaneously under the cotriggering of tumoral inherent acidic condition and ultrasound (US) irradiation, concurrently accompanying with CO2 generation and HMME release with spatial/temporal resolution...
November 15, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29140815/neuroimaging-diagnostic-and-monitoring-approaches-in-ophthalmology
#8
Bart K Chwalisz, Marc A Bouffard, Sashank Prasad, Dean M Cestari
PURPOSE OF REVIEW: We review new applications of optical coherence tomography (OCT) technology in neuro-ophthalmology. We also describe new technologies for visualizing the extracranial vessels in the diagnosis of giant cell arteritis (GCA). RECENT FINDINGS: Newer OCT modalities are expanding the evaluation of the optic disc, and are being applied to a number of neurologic conditions such as demyelinating and neurodegenerative disease. Swept-source OCT and enhanced-depth imaging OCT are refining the fine-grained analysis of the optic nerve head in the diagnosis of papilledema and optic nerve drusen...
November 14, 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29138364/retrograde-cto-pci-of-native-coronary-arteries-via-left-internal-mammary-artery-grafts-insights-from-a-multicenter-u-s-registry
#9
Peter Tajti, Aris Karatasakis, Dimitri Karmpaliotis, Khaldoon Alaswad, Farouc A Jaffer, Robert W Yeh, Mitul Patel, Ehtisham Mahmud, James W Choi, Anthony H Doing, Catalin Toma, Barry Uretsky, Santiago Garcia, Jeffrey W Moses, Manish Parikh, Ajay Kirtane, Ziad A Ali, Raja Hatem, Judit Karacsonyi, Barbara A Danek, Bavana V Rangan, Subhash Banerjee, Imre Ungi, Emmanouil S Brilakis
BACKGROUND: Retrograde percutaneous coronary intervention (PCI) of native coronary artery chronic total occlusion (CTO) via left internal mammary artery (LIMA) graft has received limited study. METHODS AND RESULTS: We compared the clinical and procedural characteristics and outcomes of retrograde CTO-PCI through LIMA grafts vs other conduits in a contemporary multicenter CTO registry. The LIMA was used as the collateral channel in 20 of 990 retrograde CTO-PCIs (2...
November 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29137792/effects-of-radiator-shapes-on-the-bubble-diving-and-dispersion-of-ultrasonic-argon-process
#10
Xuan Liu, Jilai Xue, Qiang Zhao, Qichi Le, Zhiqiang Zhang
In this work, three ultrasonic radiators in different shapes have been designed in order to investigate the effects of radiator shapes on the argon bubble dispersion and diving as well as the degassing efficiency on magnesium melt. The radiator shape has a strong influence on the bubble diving and dispersion by ultrasound. A massive argon bubble slowly flows out from the radiator with the hemispherical cap, due to the covering hemispherical cap. Using a concave radiator can intensively crush the argon bubbles and drive them much deep into the water/melt, depending on the competition between the argon flow and opposite joint shear force from the concave surface...
March 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29136193/early-first-trimester-uteroplacental-flow-and-the-progressive-disintegration-of-spiral-artery-plugs-new-insights-from-contrast-enhanced-ultrasound-and-tissue-histopathology
#11
V H J Roberts, T K Morgan, P Bednarek, M Morita, G J Burton, J O Lo, A E Frias
STUDY QUESTION: Does the use of a vascular contrast agent facilitate earlier detection of maternal flow to the placental intervillous space (IVS) in the first trimester of pregnancy? SUMMARY ANSWER: Microvascular filling of the IVS was demonstrated by contrast-enhanced ultrasound from 6 weeks of gestation onwards, earlier than previously believed. WHAT IS KNOWN ALREADY: During placental establishment and remodeling of maternal spiral arteries, endovascular trophoblast cells invade and accumulate in the lumen of these vessels to form 'trophoblast plugs'...
November 10, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29133170/hydronephrosis-and-crossing-vessels-in-children-optimization-of-diagnostic-therapeutic-pathway-and-analysis-of-color-doppler-ultrasound-and-magnetic-resonance-urography-diagnostic-accuracy
#12
M C Y Wong, G Piaggio, M B Damasio, C Molinelli, S M Ferretti, A Pistorio, G Ghiggeri, M L Degl'Innocenti, A Canepa, V Incarbone, G Mattioli
INTRODUCTION: Ureteropelvic junction obstruction (UPJO) is one of the most frequent urological diseases affecting the pediatric population. It can be due to both intrinsic stenosis of the junction and extrinsic causes such as the presence of crossing vessels (CVs), which can be detected by color Doppler ultrasound (CD-US). Magnetic resonance urography (MRU) is a good alternative, but sedation and infusion of a contrast agent are required. OBJECTIVE: The aim of this study was to analyze the diagnostic accuracy of CD-US and MRU in visualizing CVs in pediatric hydronephrosis, in order to decide the correct diagnostic pathway in the pre-operative phase...
October 27, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29131837/evidence-for-congruent-impairment-in-micro-and-macrovascular-function-in-type-1-diabetes
#13
Concetta Irace, Valentina Messiniti, Bruno Tassone, Claudio Cortese, Eugene J Barrett, Agostino Gnasso
Diabetes affects large and small vessels through mechanisms only partially known. In the present study, we evaluated the function of capillaries and large arteries in subjects with type 1 diabetes mellitus (T1DM) to study the effect of chronic hyperglycemia in the absence of other cardiovascular risk factors. Twenty-five subjects with T1DM and 12 healthy age-matched controls were enrolled. Nine patients had mild or moderate retinopathy. Contrast enhanced ultrasound was used to measure perfusion of the deep forearm flexor muscle of the non-dominant arm at rest (baseline) and after an ischemic stimulus (reactive hyperemia)...
2017: PloS One
https://www.readbyqxmd.com/read/29127536/correlation-between-microcirculation-and-contrast-enhanced-ultrasonography-after-crush-injury-of-limbs
#14
Chundong Zhang, Xin Wang, Jie Tang
PURPOSE: To explore the microcirculation formation mechanism of contrast-enhanced (CE) ultrasonography imaging performance in rabbits with limb muscle crush injury. METHODS: Seventy-two New Zealand white rabbits were randomly divided into two groups. A limb muscle crush injury model was created by airing a balloon cuff device with a force of 40 kpa. CE ultrasonography parameters were detected in the first group. In vivo microcirculation parameters were detected in the second group...
November 10, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/29122223/the-utility-of-ultrasound-superb-microvascular-imaging-for-evaluation-of-breast-tumour-vascularity-comparison-with-colour-and-power-doppler-imaging-regarding-diagnostic-performance
#15
A Y Park, B K Seo, O H Woo, K S Jung, K R Cho, E K Park, S H Cha, J Cha
AIM: To investigate the utility of superb microvascular imaging (SMI) for evaluating the vascularity of breast masses in comparison with colour or power Doppler ultrasound (US) and the effect on diagnostic performance. MATERIALS AND METHODS: A total of 191 biopsy-proven masses (99 benign and 92 malignant) in 166 women with greyscale, colour Doppler, power Doppler, and SMI images were enrolled in this retrospective study. Three radiologists analysed the vascular images using a three-factor scoring system to evaluate the number, morphology, and distribution of tumour vessels...
November 6, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29122129/a-new-algorithm-for-crossing-chronic-total-occlusions-from-the-asia-pacific-chronic-total-occlusion-club
#16
REVIEW
Scott A Harding, Eugene B Wu, Sidney Lo, Soo Teik Lim, Lei Ge, Ji-Yan Chen, Jie Quan, Seung-Whan Lee, Hsien-Li Kao, Etsuo Tsuchikane
Although the hybrid chronic total occlusion (CTO) algorithm had many excellent recommendations, there has been infrequent adoption in the Asia Pacific region. The Asia Pacific CTO club propose an algorithm for case selection based on the Japan-CTO score and a new CTO algorithm, which is applicable globally. This algorithm allows for differing skill sets and equipment availability and contains practical teaching for CTO percutaneous coronary intervention. Similar to the hybrid algorithm there are 3 main questions that determine whether the primary approach is antegrade or retrograde: 1) is there proximal cap ambiguity; 2) is the distal vessel of poor quality; and 3) are there interventional collaterals present...
November 13, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29121226/optical-frequency-domain-imaging-vs-intravascular-ultrasound-in-percutaneous-coronary-intervention-opinion-trial-one-year-angiographic-and-clinical-results
#17
Takashi Kubo, Toshiro Shinke, Takayuki Okamura, Kiyoshi Hibi, Gaku Nakazawa, Yoshihiro Morino, Junya Shite, Tetsuya Fusazaki, Hiromasa Otake, Ken Kozuma, Tetsuya Ioji, Hideaki Kaneda, Takeshi Serikawa, Toru Kataoka, Hisayuki Okada, Takashi Akasaka
Aims: Optical frequency domain imaging (OFDI) is a recently developed, light-based, high-resolution intravascular imaging technique. Intravascular ultrasound (IVUS) is a widely used, conventional imaging technique for guiding percutaneous coronary intervention (PCI). We aimed to demonstrate the non-inferiority of OFDI-guided PCI compared with IVUS-guided PCI in terms of clinical outcomes. Methods and results: We did a prospective, multicentre, randomized (ratio 1:1), active-controlled, non-inferiority study to compare head-to-head OFDI vs...
November 7, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29118380/delivery-of-the-gene-encoding-the-tumor-suppressor-sef-into-prostate-tumors-by-therapeutic-ultrasound-inhibits-both-tumor-angiogenesis-and-growth
#18
Sabrin Mishel, Boris Shneyer, Lina Korsensky, Orit Goldshmidt-Tran, Tom Haber, Marcelle Machluf, Dina Ron
Carcinomas constitute over 80% of all human cancer types with no effective therapy for metastatic disease. Here, we demonstrate, for the first time, the efficacy of therapeutic-ultrasound (TUS) to deliver a human tumor suppressor gene, hSef-b, to prostate tumors in vivo. Sef is downregulated in various human carcinomas, in a manner correlating with tumor aggressiveness. In vitro, hSef-b inhibited proliferation of TRAMP C2 cells and attenuated activation of ERK/MAPK and the master transcription factor NF-κB in response to FGF and IL-1/TNF, respectively...
November 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29113316/efficacy-of-sub-threshold-focused-ultrasound-irradiation-against-pancreatic-cancer-xenografts-evaluated-using-magnetic-resonance-imaging
#19
Rui Wang, Qian Guo, Yini Chen, Yihui Gao, Lei Wu, Bing Hu, Lixin Jiang
We investigated the efficacy and optimal period for using magnetic resonance imaging (MRI) to detect effects of sub-threshold focused ultrasound (FUS) irradiation. Nude mice bearing pancreatic cancer xenografts were subjected to MRI and pathology examnation before, and 24 h, 48 h, 2 weeks after irradiation, which were used to evaluate therapeutic effects of FUS. Tumor volumes were lower post-treatment than control group (P < 0.05). The T1WI turbo spin echo (T1WI-TSE) sequence was similar signal before and after treatment...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/29112643/assessment-of-fetal-congenital-heart-diseases-by-4-dimensional-ultrasound-using-spatiotemporal-image-correlation-pictorial-review
#20
Edward Araujo Júnior, Gabriele Tonni, Nathalie Jeanne Bravo-Valenzuela, Fabricio Da Silva Costa, Simon Meagher
The aim of this pictorial review is to describe the technical advances achieved through the application of 4-dimensional (4D) ultrasound using spatiotemporal image correlation (STIC) over conventional 2-dimensional ultrasound in the prenatal detection of congenital heart disease (CHD). Spatiotemporal image correlation is a volume imaging technique that simplifies fetal heart studies while providing more diagnostic information than is typically available from traditional 2-dimensional studies. Four-dimensional software allows the study of cardiac anatomy and function during a single cardiac cycle and has greatly contributed to diagnostic enhancement of CHD...
November 6, 2017: Ultrasound Quarterly
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