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salience network, brain region, fMRI

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https://www.readbyqxmd.com/read/29908310/individual-differences-in-aesthetic-engagement-are-reflected-in-resting-state-fmri-connectivity-implications-for-stress-resilience
#1
Paula G Williams, Kimberley T Johnson, Brian J Curtis, Jace B King, Jeffrey S Anderson
OBJECTIVE: Individual differences in aesthetic engagement-the propensity to be moved by art, nature, and beauty-are associated with positive health outcomes, as well as stress resilience. The purpose of the current study was to identify potential neural substrate mechanisms underlying individual differences in aesthetic engagement and reported proneness to aesthetic chill. METHODS: Data from the Human Connectome Project (HCP) 1200 Subjects Release were utilized...
June 13, 2018: NeuroImage
https://www.readbyqxmd.com/read/29878344/resting-state-functional-connectivity-after-sphenopalatine-ganglion-blocks-in-chronic-migraine-with-medication-overuse-headache-a-pilot-longitudinal-fmri-study
#2
Kaitlin Krebs, Chris Rorden, X Michelle Androulakis
OBJECTIVE: In this pilot study, the purpose is to investigate if a series of sphenopalatine ganglion (SPG) blockade treatments modulate the functional connectivity within the salience and central executive network (CEN) in chronic migraine with medication overuse headaches (CMw/MOH ). BACKGROUND: Using intranasal local anesthesia to block the SPG for the treatment of various headache disorders has been employed in clinical practice since the early 1900s. However, the exact mechanism of how SPG modulate resting state intrinsic functional brain networks connectivity remains to be elucidated...
May 2018: Headache
https://www.readbyqxmd.com/read/29845010/disrupted-functional-connectivity-in-primary-progressive-apraxia-of-speech
#3
Hugo Botha, Rene L Utianski, Jennifer L Whitwell, Joseph R Duffy, Heather M Clark, Edythe A Strand, Mary M Machulda, Nirubol Tosakulwong, David S Knopman, Ronald C Petersen, Clifford R Jack, Keith A Josephs, David T Jones
Apraxia of speech is a motor speech disorder thought to result from impaired planning or programming of articulatory movements. It can be the initial or only manifestation of a degenerative disease, termed primary progressive apraxia of speech (PPAOS). The aim of this study was to use task-free functional magnetic resonance imaging (fMRI) to assess large-scale brain network pathophysiology in PPAOS. Twenty-two PPAOS participants were identified from a prospective cohort of degenerative speech and language disorders patients...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29767624/the-maternal-brain-in-women-with-a-history-of-early-life-maltreatment-an-imagination-based-fmri-study-of-conflictual-versus-pleasant-interactions-with-children
#4
Corinne Neukel, Katja Bertsch, Anna Fuchs PhD, Anna-Lena Zietlow, Corinna Reck, Eva Moehler, Romuald Brunner, Felix Bermpohl, Sabine C Herpertz
BACKGROUND: Early-life maltreatment has severe consequences for the affected individual, and it has an impact on the next generation. To improve understanding of the intergenerational effects of abuse, we investigated the consequences of early-life maltreatment on maternal sensitivity and associated brain mechanisms during mother-child interactions. METHODS: In total, 47 mothers (22 with a history of physical and/or sexual childhood abuse and 25 without, all without current mental disorders) took part in a standardized real-life interaction with their 7- to 11-year-old child (not abused) and a subsequent functional imaging script-driven imagery task...
May 16, 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/29744802/the-role-of-the-insula-in-intuitive-expert-bug-detection-in-computer-code-an-fmri-study
#5
Joao Castelhano, Isabel C Duarte, Carlos Ferreira, Joao Duraes, Henrique Madeira, Miguel Castelo-Branco
Software programming is a complex and relatively recent human activity, involving the integration of mathematical, recursive thinking and language processing. The neural correlates of this recent human activity are still poorly understood. Error monitoring during this type of task, requiring the integration of language, logical symbol manipulation and other mathematical skills, is particularly challenging. We therefore aimed to investigate the neural correlates of decision-making during source code understanding and mental manipulation in professional participants with high expertise...
May 9, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29733816/creative-conceptual-expansion-a-combined-fmri-replication-and-extension-study-to-examine-individual-differences-in-creativity
#6
Anna Abraham, Barbara Rutter, Trisha Bantin, Christiane Hermann
The aims of this fMRI study were two-fold. The first objective of the study was to verify whether the findings associated with a previous fMRI study could be replicated in which a novel event-related experimental design was developed which rendered it possible to investigate the brain basis of creative conceptual expansion. The ability to widen the boundaries of conceptual structures is integral to creative idea generation, which makes conceptual expansion a core component of creative cognition. Creative conceptual expansion led to the engagement of brain regions that are known to be involved in the access, storage and relational integration of conceptual knowledge in the original study...
May 4, 2018: Neuropsychologia
https://www.readbyqxmd.com/read/29713176/aberrant-brain-functional-connectome-in-patients-with-obstructive-sleep-apnea
#7
Li-Ting Chen, Xiao-Le Fan, Hai-Jun Li, Cheng-Long Ye, Hong-Hui Yu, Hui-Zhen Xin, Hong-Han Gong, De-Chang Peng, Li-Ping Yan
Objective: Obstructive sleep apnea (OSA) is accompanied by widespread abnormal spontaneous regional activity related to cognitive deficits. However, little is known about the topological properties of the functional brain connectome of patients with OSA. This study aimed to use the graph theory approaches to investigate the topological properties and functional connectivity (FC) of the functional connectome in patients with OSA, based on resting-state functional magnetic resonance imaging (rs-fMRI)...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29695961/altered-functional-connectivity-of-insular-subregions-in-alzheimer-s-disease
#8
Xingyun Liu, Xiaodan Chen, Weimin Zheng, Mingrui Xia, Ying Han, Haiqing Song, Kuncheng Li, Yong He, Zhiqun Wang
Recent researches have demonstrated that the insula is the crucial hub of the human brain networks and most vulnerable region of Alzheimer's disease (AD). However, little is known about the changes of functional connectivity of insular subregions in the AD patients. In this study, we collected resting-state functional magnetic resonance imaging (fMRI) data including 32 AD patients and 38 healthy controls (HCs). By defining three subregions of insula, we mapped whole-brain resting-state functional connectivity (RSFC) and identified several distinct RSFC patterns of the insular subregions: For positive connectivity, three cognitive-related RSFC patterns were identified within insula that suggest anterior-to-posterior functional subdivisions: (1) an dorsal anterior zone of the insula that exhibits RSFC with executive control network (ECN); (2) a ventral anterior zone of insula, exhibits functional connectivity with the salience network (SN); (3) a posterior zone along the insula exhibits functional connectivity with the sensorimotor network (SMN)...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29691946/the-goal-priority-network-as-a-neural-substrate-of-conscientiousness
#9
Amanda R Rueter, Samantha V Abram, Angus W MacDonald, Aldo Rustichini, Colin G DeYoung
Conscientiousness is a personality trait associated with many important life outcomes, but little is known about the mechanisms that underlie it. We investigated its neural correlates using functional connectivity analysis in fMRI, which identifies brain regions that act in synchrony. We tested the hypothesis that a broad network resembling a combination of the salience and ventral attention networks, which we provisionally label the goal priority network (GPN), is a neural correlate of Conscientiousness. Self- and peer-ratings of Conscientiousness were collected in a community sample of adults who underwent a resting-state fMRI scan (N = 218)...
April 24, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29673322/the-spatio-temporal-dynamics-of-deviance-and-target-detection-in-the-passive-and-active-auditory-oddball-paradigm-a-sloreta-study
#10
Christoph Justen, Cornelia Herbert
BACKGROUND: Numerous studies have investigated the neural underpinnings of passive and active deviance and target detection in the well-known auditory oddball paradigm by means of event-related potentials (ERPs) or functional magnetic resonance imaging (fMRI). The present auditory oddball study investigates the spatio-temporal dynamics of passive versus active deviance and target detection by analyzing amplitude modulations of early and late ERPs while at the same time exploring the neural sources underling this modulation with standardized low-resolution brain electromagnetic tomography (sLORETA) ...
April 19, 2018: BMC Neuroscience
https://www.readbyqxmd.com/read/29593582/acute-effects-of-glucose-and-fructose-administration-on-the-neural-correlates-of-cognitive-functioning-in-healthy-subjects-a-pilot-study
#11
Davide Zanchi, Anne Christin Meyer-Gerspach, André Schmidt, Claudia Suenderhauf, Antoinette Depoorter, Jürgen Drewe, Christoph Beglinger, Bettina Karin Wölnerhanssen, Stefan Borgwardt
The present randomized double-blinded cross-over study aims to extensively study the neural correlates underpinning cognitive functions in healthy subjects after acute glucose and fructose administration, using an integrative multimodal neuroimaging approach. Five minutes after glucose, fructose, or placebo administration through a nasogastric tube, 12 participants underwent 3 complementary neuroimaging techniques: 2 task-based functional magnetic resonance imaging (fMRI) sequences to assess working memory (N-back) and response inhibition (Go/No-Go) and one resting state fMRI sequence to address the cognition-related fronto-parietal network (FPN) and salience network (SN)...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29581420/aberrant-salience-network-functional-connectivity-in-auditory-verbal-hallucinations-a-first-episode-psychosis-sample
#12
Pavan Kumar Mallikarjun, Paris Alexandros Lalousis, Thomas Frederick Dunne, Kareen Heinze, Renate Lep Reniers, Matthew R Broome, Baldeep Farmah, Femi Oyebode, Stephen J Wood, Rachel Upthegrove
Auditory verbal hallucinations (AVH) often lead to distress and functional disability, and are frequently associated with psychotic illness. Previously both state and trait magnetic resonance imaging (MRI) studies of AVH have identified activity in brain regions involving auditory processing, language, memory and areas of default mode network (DMN) and salience network (SN). Current evidence is clouded by research mainly in participants on long-term medication, with chronic illness and by choice of seed regions made 'a priori'...
March 27, 2018: Translational Psychiatry
https://www.readbyqxmd.com/read/29572771/brain-functional-connectivity-correlates-of-coping-styles
#13
Emiliano Santarnecchi, Giulia Sprugnoli, Elisa Tatti, Lucia Mencarelli, Francesco Neri, Davide Momi, Giorgio Di Lorenzo, Alvaro Pascual-Leone, Simone Rossi, Alessandro Rossi
Coping abilities represent the individual set of mental and behavioral strategies adopted when facing stress or traumatic experiences. Coping styles related to avoidance have been linked to a disposition to develop psychiatric disorders such as PTSD, anxiety, and major depression, whereas problem-oriented coping skills have been positively correlated with well-being and high quality of life. Even though coping styles constitute an important determinant of resilience and can impact many aspects of everyday living, no study has investigated their brain functional connectivity underpinnings in humans...
June 2018: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/29568689/both-activated-and-less-activated-regions-identified-by-functional-mri-reconfigure-to-support-task-executions
#14
Nianming Zuo, Zhengyi Yang, Yong Liu, Jin Li, Tianzi Jiang
Introduction: Functional magnetic resonance imaging (fMRI) has become very important for noninvasively characterizing BOLD signal fluctuations, which reflect the changes in neuronal firings in the brain. Unlike the activation detection strategy utilized with fMRI, which only emphasizes the synchronicity between the functional nodes (activated regions) and the task design, brain connectivity and network theory are able to decipher the interactive structure across the entire brain. However, little is known about whether and how the activated/less-activated interactions are associated with the functional changes that occur when the brain changes from the resting state to a task state...
January 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29535614/large-scale-brain-networks-supporting-divided-attention-across-spatial-locations-and-sensory-modalities
#15
Valerio Santangelo
Higher-order cognitive processes were shown to rely on the interplay between large-scale neural networks. However, brain networks involved with the capability to split attentional resource over multiple spatial locations and multiple stimuli or sensory modalities have been largely unexplored to date. Here I re-analyzed data from Santangelo et al. (2010) to explore the causal interactions between large-scale brain networks during divided attention. During fMRI scanning, participants monitored streams of visual and/or auditory stimuli in one or two spatial locations for detection of occasional targets...
2018: Frontiers in Integrative Neuroscience
https://www.readbyqxmd.com/read/29527476/connectome-wide-investigation-of-altered-resting-state-functional-connectivity-in-war-veterans-with-and-without-posttraumatic-stress-disorder
#16
Masaya Misaki, Raquel Phillips, Vadim Zotev, Chung-Ki Wong, Brent E Wurfel, Frank Krueger, Matthew Feldner, Jerzy Bodurka
Altered resting-state functional connectivity in posttraumatic stress disorder (PTSD) suggests neuropathology of the disorder. While seed-based fMRI connectivity analysis is often used for the studies, such analysis requires defining a seed location a priori , which restricts search scope and could bias findings toward presupposed areas. Recently, a comprehensive exploratory voxel-wise connectivity analysis, the connectome-wide association approach, has been introduced using multivariate distance matrix regression (MDMR) for resting-state functional connectivity analysis...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29498761/aberrant-functional-network-connectivity-in-psychopathy-from-a-large-n-985-forensic-sample
#17
Flor A Espinoza, Victor M Vergara, Daisy Reyes, Nathaniel E Anderson, Carla L Harenski, Jean Decety, Srinivas Rachakonda, Eswar Damaraju, Barnaly Rashid, Robyn L Miller, Michael Koenigs, David S Kosson, Keith Harenski, Kent A Kiehl, Vince D Calhoun
Psychopathy is a personality disorder characterized by antisocial behavior, lack of remorse and empathy, and impaired decision making. The disproportionate amount of crime committed by psychopaths has severe emotional and economic impacts on society. Here we examine the neural correlates associated with psychopathy to improve early assessment and perhaps inform treatments for this condition. Previous resting-state functional magnetic resonance imaging (fMRI) studies in psychopathy have primarily focused on regions of interest...
June 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29497705/amygdala-adaptation-and-temporal-dynamics-of-the-salience-network-in-conditioned-fear-a-single-trial-fmri-study
#18
Siyang Yin, Yuelu Liu, Nathan M Petro, Andreas Keil, Mingzhou Ding
Research in rodents has established the role of the amygdaloid complex in defensive responses to conditioned threat. In human imaging studies, however, activation of the amygdala by conditioned threat cues is often not observed. One hypothesis states that this finding reflects adaptation of amygdaloid responses over time. We tested this hypothesis by estimating single-trial neural responses over a large number of conditioning trials. Functional MRI (fMRI) was recorded from 18 participants during classical differential fear conditioning: Participants viewed oriented grayscale grating stimuli (45° or 135°) presented centrally in random order...
January 2018: ENeuro
https://www.readbyqxmd.com/read/29488069/decoding-auditory-saliency-from-brain-activity-patterns-during-free-listening-to-naturalistic-audio-excerpts
#19
Shijie Zhao, Junwei Han, Xi Jiang, Heng Huang, Huan Liu, Jinglei Lv, Lei Guo, Tianming Liu
In recent years, natural stimuli such as audio excerpts or video streams have received increasing attention in neuroimaging studies. Compared with conventional simple, idealized and repeated artificial stimuli, natural stimuli contain more unrepeated, dynamic and complex information that are more close to real-life. However, there is no direct correspondence between the stimuli and any sensory or cognitive functions of the brain, which makes it difficult to apply traditional hypothesis-driven analysis methods (e...
February 27, 2018: Neuroinformatics
https://www.readbyqxmd.com/read/29475059/ventrolateral-motor-thalamus-abnormal-connectivity-in-essential-tremor-before-and-after-thalamotomy-a-resting-state-functional-magnetic-resonance-imaging-study
#20
Constantin Tuleasca, Elena Najdenovska, Jean Régis, Tatiana Witjas, Nadine Girard, Jérôme Champoudry, Mohamed Faouzi, Jean-Philippe Thiran, Meritxell Bach Cuadra, Marc Levivier, Dimitri Van De Ville
OBJECTIVE: To evaluate functional connectivity (FC) of the ventrolateral thalamus, a common target for drug-resistant essential tremor (ET), resting-state data were analyzed before and 1 year after stereotactic radiosurgical thalamotomy and compared against healthy controls (HCs). METHODS: In total, 17 consecutive patients with ET and 10 HCs were enrolled. Tremor network was investigated using the ventrolateral ventral (VLV) thalamic nucleus as the region of interest, extracted with automated segmentation from pretherapeutic diffusion magnetic resonance imaging...
May 2018: World Neurosurgery
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