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Ogdie, alexis

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https://www.readbyqxmd.com/read/29858357/proceedings-of-the-2017-grappa-collaborative-research-network-meeting
#1
Deepak R Jadon, Vinod Chandran, Carmel Stober, Alexis Ogdie, April W Armstrong, Kristina Callis Duffin, Dafna D Gladman, Philip S Helliwell, Denis O'Sullivan, Maarten de Wit, Oliver FitzGerald, Christopher T Ritchlin
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) Collaborative Research Network (CRN) is an endeavor that aims to address gaps in the knowledge of the etiopathogenesis and management of psoriatic disease by best using the large community of experienced investigators who are already collecting rich clinical phenotype data and biologic samples using validated techniques. Exemplar rheumatology and dermatology projects will inform strategies to implement the CRN, while input and funding from government organizations, charities, and industry will shape the CRN...
June 2018: Journal of Rheumatology. Supplement
https://www.readbyqxmd.com/read/29858355/grappa-2017-project-report
#2
Kristina Callis Duffin, Oliver FitzGerald, Artie Kavanaugh, Philip J Mease, Joseph F Merola, Alexis Ogdie, Denis O'Sullivan, Soumya M Reddy, Christopher T Ritchlin, Laura C Coates
At the 2017 annual meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), members received updates on several ongoing educational and research efforts. Among them were updates on GRAPPA's continued education efforts; GRAPPA's continued research efforts, including the Biomarker Project, a collaborative research effort to identify and study biomarkers of joint damage; treatment recommendations, including recommendations and core principles related to biosimilars; efforts to update GRAPPA's Website and to create a GRAPPA smart-phone application (app); and the Psoriasis and Psoriatic Arthritis Clinics Multicenter Advancement Network...
June 2018: Journal of Rheumatology. Supplement
https://www.readbyqxmd.com/read/29858348/content-and-face-validity-and-feasibility-of-5-candidate-instruments-for-psoriatic-arthritis-randomized-controlled-trials-the-psa-omeract-core-set-workshop-at-the-grappa-2017-annual-meeting
#3
Richard Holland, William Tillett, Alexis Ogdie, Ying Y Leung, Dafna D Gladman, Kristina Callis Duffin, Laura C Coates, Philip J Mease, Lihi Eder, Vibeke Strand, Musaab Elmamoun, Pil Højgaard, Jeffrey Chau, Maarten de Wit, Niti Goel, Chris A Lindsay, Oliver FitzGerald, Bev Shea, Dorcas Beaton, Ana-Maria Orbai
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)-Outcome Measures in Rheumatology (OMERACT) Psoriatic Arthritis (PsA) Core Set working group is in the process of selecting core instruments for PsA clinical trials. During a 2-h workshop and breakout group discussions at the GRAPPA 2017 annual meeting in Amsterdam, the Netherlands, participants discussed the first set of candidate instruments to be taken through the OMERACT Filter 2.1 instrument selection process: 66/68 swollen/tender joint count (66/68JC), Spondyloarthritis Consortium of Canada (SPARCC) enthesitis index, patient's global assessment (GRAPPA and OMERACT formulations), Health Assessment Questionnaire-Disability Index (HAQ-DI), Psoriatic Arthritis Impact of Disease (PsAID) questionnaires 9 and 12, and Functional Assessment of Chronic Illness Therapy (FACIT) Fatigue...
June 2018: Journal of Rheumatology. Supplement
https://www.readbyqxmd.com/read/29756094/the-2017-national-psoriasis-foundation-research-symposium
#4
Michael Siegel, Lindsey Shankle, Samuel Hwang, Alexis Ogdie
No abstract text is available yet for this article.
January 2018: Journal of Psoriasis and Psoriatic Arthritis
https://www.readbyqxmd.com/read/29688897/frequency-and-predictors-of-communication-about-high-blood-pressure-in-rheumatoid-arthritis-visits
#5
Christie Michels Bartels, Heather Johnson, Katya Alcaraz Voelker, Alexis Ogdie, Patrick McBride, Elizabeth A Jacobs, Ying-Qi Zhao, Maureen Smith
BACKGROUND/OBJECTIVE: Given heightened cardiovascular disease (CVD) risk in rheumatoid arthritis (RA) and that higher blood pressure (BP) represents greater CVD risk, we hypothesized that higher BP would predict more BP-related communication in rheumatology visits. We examined predictors of documented BP communication during RA clinic visits. METHODS: This was a retrospective cohort study of RA patients identified in electronic health record records with uncontrolled hypertension (HTN) receiving both primary and rheumatology care...
June 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29505759/risk-of-serious-infection-opportunistic-infection-and-herpes-zoster-among-patients-with-psoriasis-in-the-united-kingdom
#6
Junko Takeshita, Daniel B Shin, Alexis Ogdie, Joel M Gelfand
The risk of infection among patients with psoriasis of varying severity in a broadly representative population remains poorly understood. Using The Health Improvement Network (THIN), an electronic medical records database representative of the general UK population, we performed a cohort study to determine the risks of serious infection, opportunistic infection, and herpes zoster among patients with versus without psoriasis and according to psoriasis severity. We identified 187,258 patients with mild and 12,442 patients with moderate to severe psoriasis based on treatment patterns...
March 2, 2018: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29449495/evaluation-of-self-reported-patient-experiences-insights-from-digital-patient-communities-in-psoriatic-arthritis
#7
Prashanth Sunkureddi, Stephen Doogan, John Heid, Samir Benosman, Alexis Ogdie, Layne Martin, Jacqueline B Palmer
OBJECTIVE: To evaluate the types of experiences and treatment access challenges of patients with psoriatic arthritis (PsA) using self-reported online narratives. METHODS: English-language patient narratives reported between January 2010 and May 2016 were collected from 31 online sources (general health social networking sites, disease-focused patient forums, treatment reviews, general health forums, mainstream social media sites) for analysis of functional impairment and 40 online sources for assessment of barriers to treatment...
May 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29193765/group-for-research-and-assessment-of-psoriasis-and-psoriatic-arthritis-outcome-measures-in-rheumatology-consensus-based-recommendations-and-research-agenda-for-use-of-composite-measures-and-treatment-targets-in-psoriatic-arthritis
#8
Laura C Coates, Oliver FitzGerald, Joseph F Merola, Josef Smolen, Leonieke J J van Mens, Heidi Bertheussen, Wolf-Henning Boehncke, Kristina Callis Duffin, Willemina Campbell, Maarten de Wit, Dafna Gladman, Alice Gottlieb, Jana James, Arthur Kavanaugh, Lars Erik Kristensen, Tore K Kvien, Thomas Luger, Neil McHugh, Philip Mease, Peter Nash, Alexis Ogdie, Cheryl F Rosen, Vibeke Strand, William Tillett, Douglas J Veale, Philip S Helliwell
OBJECTIVE: A meeting was convened by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) and Outcome Measures in Rheumatology (OMERACT) to further the development of consensus among physicians and patients regarding composite disease activity measures and targets in psoriatic arthritis (PsA). METHODS: Prior to the meeting, physicians and patients completed surveys on outcome measures. A consensus meeting of 26 rheumatologists, dermatologists, and patient research partners reviewed evidence on composite measures and potential treatment targets plus results of the surveys...
March 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29139030/potential-risk-factors-for-reactive-arthritis-and-persistence-of-symptoms-at-2-years-a-case-control-study-with-longitudinal-follow-up
#9
Helga Raquel Garcia Ferrer, Alexander Azan, Isa Iraheta, Joan Von Feldt, Luis R Espinoza, Julia Manasson, Jose U Scher, Abraham Garcia Kutzbach, Alexis Ogdie
The objective of the study is to determine the risk factors for the development of reactive arthritis (ReA) and examine the factors associated with the persistence of symptoms. Patients with a new diagnosis of ReA and controls with a gastrointestinal (GI), urogenital, or sexually transmitted infection in the 3-6 months prior to study entry were prospectively enrolled in Guatemala City. ReA patients fulfilled the Assessment in Spondyloarthritis International Society criteria for peripheral spondyloarthropathy (SpA)...
February 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29104161/risk-of-incident-liver-disease-in-patients-with-psoriasis-psoriatic-arthritis-and-rheumatoid-arthritis-a-population-based-study
#10
Alexis Ogdie, Sungat K Grewal, Megan H Noe, Daniel B Shin, Junko Takeshita, Zelma C Chiesa Fuxench, Rotonya M Carr, Joel M Gelfand
Relatively little is known about the risk for incident liver disease in psoriasis (PsO), psoriatic arthritis (PsA), and rheumatoid arthritis (RA). We performed a cohort study among patients with PsO, PsA, or RA and matched controls in The Health Improvement Network from 1994 to 2014. Outcomes of interest were any liver disease, nonalcoholic fatty liver disease, and cirrhosis (any etiology). Among patients with PsO (N = 197,130), PsA (N = 12,308), RA (N = 54,251), and matched controls (N = 1,279,754), the adjusted hazard ratios for any liver disease were elevated among patients with PsO (without systemic therapy [ST] 1...
April 2018: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29102956/smoking-paradox-in-the-development-of-psoriatic-arthritis-among-patients-with-psoriasis-a-population-based-study
#11
Uyen-Sa D T Nguyen, Yuqing Zhang, Na Lu, Qiong Louie-Gao, Jingbo Niu, Alexis Ogdie, Joel M Gelfand, Michael P LaValley, Maureen Dubreuil, Jeffrey A Sparks, Elizabeth W Karlson, Hyon K Choi
OBJECTIVES: Smoking is associated with an increased risk of psoriatic arthritis (PsA) in the general population, but not among patients with psoriasis. We sought to clarify the possible methodological mechanisms behind this paradox. METHODS: Using 1995-2015 data from The Health Improvement Network, we performed survival analysis to examine the association between smoking and incident PsA in the general population and among patients with psoriasis. We clarified the paradox using mediation analysis and conducted bias sensitivity analyses to evaluate the potential impact of index event bias and quantify its magnitude from uncontrolled/unmeasured confounders...
January 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29073348/gut-microbiota-perturbations-in-reactive-arthritis-and-postinfectious-spondyloarthritis
#12
Julia Manasson, Nan Shen, Helga R Garcia Ferrer, Carles Ubeda, Isa Iraheta, Adriana Heguy, Joan M Von Feldt, Luis R Espinoza, Abraham Garcia Kutzbach, Leopoldo N Segal, Alexis Ogdie, Jose C Clemente, Jose U Scher
OBJECTIVE: Reactive arthritis (ReA) is an inflammatory disorder occurring several weeks after gastrointestinal or genitourinary tract infections. HLA-B27 positivity is considered a risk factor, although it is not necessarily predictive of disease incidence. Among nongenetic factors, the intestinal microbiome may play a role in disease susceptibility. The objective of this study was to characterize the gut microbiota and host gene interactions in ReA and postinfectious spondyloarthritis...
February 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29037523/a-systematic-review-of-measurement-properties-of-patient-reported-outcome-measures-in-psoriatic-arthritis-a-grappa-omeract-initiative
#13
REVIEW
Pil Højgaard, Louise Klokker, Ana-Maria Orbai, Kim Holmsted, Else M Bartels, Ying Ying Leung, Niti Goel, Maarten de Wit, Dafna D Gladman, Philip Mease, Lene Dreyer, Lars E Kristensen, Oliver FitzGerald, William Tillett, Laure Gossec, Philip Helliwell, Vibeke Strand, Alexis Ogdie, Caroline B Terwee, Robin Christensen
BACKGROUND: An updated psoriatic arthritis (PsA) core outcome set (COS) for randomized controlled trials (RCTs) was endorsed at the Outcome Measures in Rheumatology (OMERACT) meeting in 2016. OBJECTIVES: To synthesize the evidence on measurement properties of patient reported outcome measures (PROMs) for PsA and thereby contribute to development of a PsA core outcome measurement set (COMS) as described by the OMERACT Filter 2.0. METHODS: A systematic literature search was performed in EMBASE, MEDLINE and PsycINFO on Jan 1, 2017 to identify full-text articles with an aim of assessing the measurement properties of PROMs in PsA...
April 2018: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28993952/discordance-of-the-framingham-cardiovascular-risk-score-and-the-2013-american-college-of-cardiology-american-heart-association-risk-score-in-systemic-lupus-erythematosus-and-rheumatoid-arthritis
#14
Kashif Jafri, Alexis Ogdie, Atif Qasim, Sarah L Patterson, Milena Gianfrancesco, Zara Izadi, Patricia Katz, Jinoos Yazdany, Gabriela Schmajuk
Despite the increasing use of the 2013 American College of Cardiology/American Heart Association (ACC/AHA) cardiovascular (CV) risk score in clinical practice, few studies have compared this score to the Framingham risk score among rheumatologic patients. We calculated Framingham and 2013 ACC/AHA risk scores in subjects with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) and assessed demographic, CV, and rheumatologic characteristics associated with discordant scores (high-risk ACC/AHA scores but low-risk Framingham scores)...
February 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/28992298/incidence-of-pneumocystis-jirovecii-and-adverse-events-associated-with-pneumocystis-prophylaxis-in-children-receiving-glucocorticoids
#15
Matthew L Basiaga, Michelle E Ross, Jeffrey S Gerber, Alexis Ogdie
Background: Antimicrobial prophylaxis is indicated to prevent Pneumocystis jirovecii pneumonia (PJP) in profoundly immunosuppressed children. The incidence of PJP infection in children with chronic glucocorticoid exposure is unknown, and PJP prophylaxis has been associated with adverse events. We hypothesized that PJP infection is rare in children without human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), cancer, or a transplant history who are using chronic glucocorticoids and that those exposed to PJP prophylaxis are more likely to experience a cutaneous hypersensitivity reaction or myelosuppression than unexposed patients...
July 13, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28684559/treating-axial-spondyloarthritis-and-peripheral-spondyloarthritis-especially-psoriatic-arthritis-to-target-2017-update-of-recommendations-by-an-international-task-force
#16
Josef S Smolen, Monika Schöls, Jürgen Braun, Maxime Dougados, Oliver FitzGerald, Dafna D Gladman, Arthur Kavanaugh, Robert Landewé, Philip Mease, Joachim Sieper, Tanja Stamm, Maarten de Wit, Daniel Aletaha, Xenofon Baraliakos, Neil Betteridge, Filip van den Bosch, Laura C Coates, Paul Emery, Lianne S Gensler, Laure Gossec, Philip Helliwell, Merryn Jongkees, Tore K Kvien, Robert D Inman, Iain B McInnes, Mara Maccarone, Pedro M Machado, Anna Molto, Alexis Ogdie, Denis Poddubnyy, Christopher Ritchlin, Martin Rudwaleit, Adrian Tanew, Bing Thio, Douglas Veale, Kurt de Vlam, Désirée van der Heijde
Therapeutic targets have been defined for axial and peripheral spondyloarthritis (SpA) in 2012, but the evidence for these recommendations was only of indirect nature. These recommendations were re-evaluated in light of new insights. Based on the results of a systematic literature review and expert opinion, a task force of rheumatologists, dermatologists, patients and a health professional developed an update of the 2012 recommendations. These underwent intensive discussions, on site voting and subsequent anonymous electronic voting on levels of agreement with each item...
January 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28544766/barriers-and-facilitators-of-mentoring-for-trainees-and-early-career-investigators-in-rheumatology-research-current-state-identification-of-needs-and-road-map-to-an-inter-institutional-adult-rheumatology-mentoring-program
#17
Alexis Ogdie, Jeffrey A Sparks, Sheila T Angeles-Han, Kathleen Bush, Flavia V Castelino, Amit Golding, Yihui Jiang, J Michelle Kahlenberg, Alfred H J Kim, Yvonne C Lee, Kirthi Machireddy, Michael J Ombrello, Ami A Shah, Zachary S Wallace, Peter A Nigrovic, Una E Makris
OBJECTIVE: To determine perceived barriers and facilitators to effective mentoring for early career rheumatology investigators and to develop a framework for an inter-institutional mentoring program. METHODS: Focus groups or interviews with rheumatology fellows, junior faculty, and mentors were conducted, audiorecorded, and transcribed. Content analysis was performed using NVivo software. Themes were grouped into categories (e.g., mentor-mentee relationship, barriers, and facilitators of a productive relationship)...
March 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/28490202/tumor-necrosis-factor-inhibitors-in-psoriatic-arthritis
#18
REVIEW
Santhi Mantravadi, Alexis Ogdie, Walter K Kraft
Psoriatic arthritis (PsA) is a chronic inflammatory disease that can result in significant disability. With the emergence of tumor necrosis factor inhibitors (TNFi), therapeutic outcomes in PsA have improved substantially. The clinical efficacy and the inhibition of radiographic progression demonstrated by TNFi have transformed the management of PsA. However, there is still an unmet need for a subset of patients who do not respond adequately to TNFi. Areas covered: This review provides an overview of the pharmacokinetics of TNFi, the efficacy of TNFi in PsA, and the role of immunogenicity of TNFi in the treatment of PsA...
August 2017: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/28461533/tackling-patient-centricity-a-report-from-the-grappa-2016-annual-meeting
#19
Niti Goel, Denis O'Sullivan, Ingrid Steinkoenig, Jana James, Chris A Lindsay, Laura C Coates, John Latella, Alexis Ogdie, Jeffrey Chau, Heidi Bertheussen, Willemina Campbell
In line with the global trend to have disease-related organizations be more patient-centric in their approach, the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) has made substantial progress incorporating patient research partners (PRP) into psoriatic arthritis and psoriasis research. Herein we summarize the involvement of PRP at the GRAPPA 2016 annual meeting. Plans for future PRP engagement were also discussed.
May 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28461531/defining-outcome-measures-for-psoriatic-arthritis-a-report-from-the-grappa-omeract-working-group
#20
Alexis Ogdie, Maarten de Wit, Kristina Callis Duffin, Willemina Campbell, Jeffrey Chau, Laura C Coates, Lihi Eder, Musaab Elmamoun, Oliver FitzGerald, Dafna D Gladman, Niti Goel, Jana James, Umut Kalyoncu, John Latella, Chris Lindsay, Philip J Mease, Denis O'Sullivan, Ingrid Steinkoenig, Vibeke Strand, William Tillett, Ana-Maria Orbai
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)-Outcome Measures in Rheumatology (OMERACT) Psoriatic Arthritis (PsA) Core Set working group recently published the updated 2016 psoriatic arthritis (PsA) core domain set, a set of disease features that should be measured in all clinical trials. At the GRAPPA annual meeting in July 2016, the PsA working group presented the updated PsA core domain set endorsed by 90% of participants at OMERACT in May 2016 and drafted a roadmap for the development of the PsA core outcome measurement set...
May 2017: Journal of Rheumatology
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