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https://www.readbyqxmd.com/read/28345164/comparing-functional-mri-protocols-for-small-iron-rich-basal-ganglia-nuclei-such-as-the-subthalamic-nucleus-at-7-t-and-3-t
#1
Gilles de Hollander, Max C Keuken, Wietske van der Zwaag, Birte U Forstmann, Robert Trampel
The basal ganglia (BG) form a network of subcortical nuclei. Functional magnetic resonance imaging (fMRI) in the BG could provide insight in its functioning and the underlying mechanisms of Deep Brain Stimulation (DBS). However, fMRI of the BG with high specificity is challenging, because the nuclei are small and variable in their anatomical location. High resolution fMRI at field strengths of 7 Tesla (T) could help resolve these challenges to some extent. A set of MR protocols was developed for functional imaging of the BG nuclei at 3 T and 7 T...
March 27, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28345153/the-functional-architectures-of-addition-and-subtraction-network-discovery-using-fmri-and-dcm
#2
Yang Yang, Ning Zhong, Karl Friston, Kazuyuki Imamura, Shengfu Lu, Mi Li, Haiyan Zhou, Haiyuan Wang, Kuncheng Li, Bin Hu
The neuronal mechanisms underlying arithmetic calculations are not well understood but the differences between mental addition and subtraction could be particularly revealing. Using fMRI and dynamic causal modeling (DCM), this study aimed to identify the distinct neuronal architectures engaged by the cognitive processes of simple addition and subtraction. Our results revealed significantly greater activation during subtraction in regions along the dorsal pathway, including the left inferior frontal gyrus (IFG), middle portion of dorsolateral prefrontal cortex (mDLPFC), and supplementary motor area (SMA), compared with addition...
March 27, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28345150/decoding-facial-expressions-based-on-face-selective-and-motion-sensitive-areas
#3
Yin Liang, Baolin Liu, Junhai Xu, Gaoyan Zhang, Xianglin Li, Peiyuan Wang, Bin Wang
Humans can easily recognize others' facial expressions. Among the brain substrates that enable this ability, considerable attention has been paid to face-selective areas; in contrast, whether motion-sensitive areas, which clearly exhibit sensitivity to facial movements, are involved in facial expression recognition remained unclear. The present functional magnetic resonance imaging (fMRI) study used multi-voxel pattern analysis (MVPA) to explore facial expression decoding in both face-selective and motion-sensitive areas...
March 27, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28344549/functional-brain-activation-in-response-to-a-clinical-vestibular-test-correlates-with-balance
#4
Fatemeh Noohi, Catherine Kinnaird, Yiri DeDios, Igor S Kofman, Scott Wood, Jacob Bloomberg, Ajitkumar Mulavara, Rachael Seidler
The current study characterizes brain fMRI activation in response to two modes of vestibular stimulation: Skull tap and auditory tone burst. The auditory tone burst has been used in previous studies to elicit either a vestibulo-spinal reflex [saccular-mediated colic Vestibular Evoked Myogenic Potentials (cVEMP)], or an ocular muscle response [utricle-mediated ocular VEMP (oVEMP)]. Research suggests that the skull tap elicits both saccular and utricle-mediated VEMPs, while being faster and less irritating for subjects than the high decibel tones required to elicit VEMPs...
2017: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/28344152/trait-based-food-cravings-are-encoded-by-regional-homogeneity-in-the-parahippocampal-gyrus
#5
Shuaiyu Chen, Debo Dong, Todd Jackson, Qian Zhuang, Hong Chen
Food cravings can reflect an intense trait-like emotional-motivational desire to eat palatable food, often resulting in the failure of weight loss efforts. Studies have linked trait-based food-cravings to increased risk of overeating. However, little is known about resting-state neural mechanisms that underlie food cravings. We investigated this issue using resting-state functional magnetic resonance imaging (fMRI) to test the extent to which spontaneous neural activity occurs in regions implicated in emotional memory and reward motivation associated with food cravings...
March 23, 2017: Appetite
https://www.readbyqxmd.com/read/28344075/functional-reorganization-in-obstructive-sleep-apnoea-and-insomnia-a-systematic-review-of-the-resting-state-fmri
#6
REVIEW
Habibolah Khazaie, Mattia Veronese, Khadijeh Noori, Farnoosh Emamian, Mojtaba Zarei, Keyoumars Ashkan, Guy D Leschziner, Claudia R Eickhoff, Simon B Eickhoff, Mary J Morrell, Ricardo S Osorio, Kai Spiegelhalder, Masoud Tahmasian, Ivana Rosenzweig
Functional neuroimaging techniques have accelerated progress in the study of sleep disorders. Considering the striking prevalence of these disorders in the general population, however, as well as their strong bidirectional relationship with major neuropsychiatric disorders, including major depressive disorder, their numbers are still surprisingly low. This review examines the contribution of resting state functional MRI to current understanding of two major sleep disorders, insomnia disorder and obstructive sleep apnoea...
March 23, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28342970/not-in-one-metric-neuroticism-modulates-different-resting-state-metrics-within-distinctive-brain-regions
#7
Claudio Gentili, Ioana Alina Cristea, Emiliano Ricciardi, Nicola Vanello, Cristian Popita, Daniel David, Pietro Pietrini
INTRODUCTION: Neuroticism is a complex personality trait encompassing diverse aspects. Notably, high levels of neuroticism are related to the onset of psychiatric conditions, including anxiety and mood disorders. Personality traits are stable individual features; therefore, they can be expected to be associated with stable neurobiological features, including the Brain Resting State (RS) activity as measured by fMRI. Several metrics have been used to describe RS properties, yielding rather inconsistent results...
March 22, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28342897/dose-response-effect-of-acute-phencyclidine-on-functional-connectivity-and-dopamine-levels-and-their-association-with-schizophrenia-like-symptom-classes-in-rat
#8
Jaakko Paasonen, Raimo A Salo, Jouni Ihalainen, Juuso V Leikas, Katja Savolainen, Marko Lehtonen, Markus M Forsberg, Olli Gröhn
Current drug treatments for schizophrenia (SCZ) can alleviate positive symptoms, but have little effect on the negative symptoms and cognitive deficits that are difficult to translate into preclinical models for drug development. Therefore, we aimed to determine the dose-response effects of acute phencyclidine (PCP, 1.0-5.0 mg/kg) on rat brain connectivity and detect markers for different SCZ-like symptoms. Pharmacological functional magnetic resonance imaging (phMRI) and microdialysis were used to investigate PCP-induced effects on functional connectivity (FC) and dopamine levels, respectively...
March 22, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28342882/functional-neuroimaging-findings-in-healthy-middle-aged-adults-at-risk-of-alzheimer-s-disease
#9
REVIEW
Mirette Habib, Elijah Mak, Silvy Gabel, Li Su, Guy Williams, Adam Waldman, Katie Wells, Karen Ritchie, Craig Ritchie, John T O'Brien
It is well established that the neurodegenerative process of Alzheimer's disease (AD) begins many years before symptom onset. This preclinical phase provides a crucial time-window for therapeutic intervention, though this requires biomarkers that could evaluate the efficacy of future disease-modification treatments in asymptomatic individuals. The last decade has witnessed a proliferation of studies characterizing the temporal sequence of the earliest functional and structural brain imaging changes in AD. These efforts have focused on studying individuals who are highly vulnerable to develop AD, such as those with familial genetic mutations, susceptibility genes (i...
March 22, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28342260/neural-decoding-of-visual-stimuli-varies-with-fluctuations-in-global-network-efficiency
#10
Luca Cocchi, Zhengyi Yang, Andrew Zalesky, Johannes Stelzer, Luke J Hearne, Leonardo L Gollo, Jason B Mattingley
Functional magnetic resonance imaging (fMRI) studies have shown that neural activity fluctuates spontaneously between different states of global synchronization over a timescale of several seconds. Such fluctuations generate transient states of high and low correlation across distributed cortical areas. It has been hypothesized that such fluctuations in global efficiency might alter patterns of activity in local neuronal populations elicited by changes in incoming sensory stimuli. To test this prediction, we used a linear decoder to discriminate patterns of neural activity elicited by face and motion stimuli presented periodically while participants underwent time-resolved fMRI...
March 25, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28342214/real-time-fmri-neurofeedback-in-adolescents-with-attention-deficit-hyperactivity-disorder
#11
Analucia A Alegria, Melanie Wulff, Helen Brinson, Gareth J Barker, Luke J Norman, Daniel Brandeis, Daniel Stahl, Anthony S David, Eric Taylor, Vincent Giampietro, Katya Rubia
Attention Deficit Hyperactivity Disorder (ADHD) is associated with poor self-control, underpinned by inferior fronto-striatal deficits. Real-time functional magnetic resonance neurofeedback (rtfMRI-NF) allows participants to gain self-control over dysregulated brain regions. Despite evidence for beneficial effects of electrophysiological-NF on ADHD symptoms, no study has applied the spatially superior rtfMRI-NF neurotherapy to ADHD. A randomized controlled trial tested the efficacy of rtfMRI-NF of right inferior prefrontal cortex (rIFG), a key region that is compromised in ADHD and upregulated with psychostimulants, on improvement of ADHD symptoms, cognition, and inhibitory fMRI activation...
March 25, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28341991/altered-interhemispheric-functional-connectivity-in-patients-with-anisometropic-and-strabismic-amblyopia-a-resting-state-fmri-study
#12
Minglong Liang, Bing Xie, Hong Yang, Xuntao Yin, Hao Wang, Longhua Yu, Sheng He, Jian Wang
PURPOSE: Altered brain functional connectivity has been reported in patients with amblyopia by recent neuroimaging studies. However, relatively little is known about the alterations in interhemispheric functional connectivity in amblyopia. The present study aimed to investigate the functional connectivity patterns between homotopic regions across hemispheres in patients with anisometropic and strabismic amblyopia under resting state. METHODS: Nineteen monocular anisometropic amblyopia (AA), 18 strabismic amblyopia (SA), and 20 normal-sight controls (NC) were enrolled in this study...
March 24, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28341165/the-left-intraparietal-sulcus-adapts-to-symbolic-number-in-both-the-visual-and-auditory-modalities-evidence-from-fmri
#13
Stephan E Vogel, Celia Goffin, Joshua Bohnenberger, Karl Koschutnig, Gernot Reishofer, Roland H Grabner, Daniel Ansari
A growing body of evidence from functional Magnetic Resonance Imaging adaptation (fMRIa) has implicated the left intraparietal sulcus (IPS) as a crucial brain region representing the semantic meaning of number symbols. However, it is currently unknown to what extent the left IPS brain activity can be generalized across modalities (e.g., Arabic digits and spoken number words) and how robust and reproducible numerical adaptation effects are. In two separate fMRIa experiments we habituated the brain response of 20 native English-speaking (Experiment 1) and 34 native German-speaking (Experiment 2) adults to Arabic digits or spoken number words...
March 21, 2017: NeuroImage
https://www.readbyqxmd.com/read/28340432/reorganization-of-anterior-and-posterior-hippocampal-networks-associated-with-memory-performance-in-mesial-temporal-lobe-epilepsy
#14
Hong Li, Caihong Ji, Lujia Zhu, Peiyu Huang, Biao Jiang, Xiaojun Xu, Jianzhong Sun, Zhong Chen, Meiping Ding, Minming Zhang, Shuang Wang
OBJECTIVE: To investigate the pattern of functional demarcation of hippocampal network and its relationship with memory performance in mesial temporal lobe epilepsy (mTLE) with unilateral hippocampal sclerosis. METHODS: Resting state fMRI data were acquired from fifteen left mTLE patients, fourteen right mTLE patients and twenty healthy subjects. We explore the hippocampal-cortical alterations and corresponding inter-hemispheric functional connectivity (FC) across anterior and posterior hippocampal networks...
March 4, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28338962/higher-order-intentionality-tasks-are-cognitively-more-demanding
#15
Penelope A Lewis, Amy Birch, Alexander Hall, R I M Dunbar
A central assumption that underpins much of the discussion of the role played by social cognition in brain evolution is that social cognition is unusually cognitively demanding. This assumption has never been tested. Here, we use a task in which participants read stories and then answered questions about the stories in a behavioural experiment (39 participants) and an fMRI experiment (17 participants) to show that mentalising requires more time for responses than factual memory of a matched complexity and also that higher orders of mentalising is disproportionately more demanding and requires the recruitment of more neurons in brain regions known to be associated with theory of mind, including insula, posterior STS, temporal pole, and cerebellum...
March 13, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28338955/the-role-of-cognitive-reappraisal-in-placebo-analgesia-an-fmri-study
#16
Marian van der Meulen, Sandra Kamping, Fernand Anton
Placebo analgesia (PA) depends crucially on the prefrontal cortex (PFC), which is assumed to be responsible for initiating the analgesic response. Surprisingly little research has focused on the psychological mechanisms mediated by the PFC and underlying PA. One increasingly accepted theory is that cognitive reappraisal - the reinterpretation of the meaning of adverse events - plays an important role, but no study has yet addressed the possible functional relationship with PA. We studied the influence of individual differences in reappraisal ability on PA and its prefrontal mediation...
March 17, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28338887/washing-away-your-sins-in-the-brain-physical-cleaning-and-priming-of-cleaning-recruit-different-brain-networks-after-moral-threat
#17
Honghong Tang, Xiaping Lu, Rui Su, Zilu Liang, Xiaoqin Mai, Chao Liu
The association between moral purity and physical cleanliness has been widely discussed recently. Studies found that moral threat initiates the need of physical cleanliness, but actual physical cleaning and priming of cleaning have inconsistent effects on subsequent attitudes and behaviors. Here we used resting-state functional magnetic resonance imaging (fMRI) to explore the underlying neural mechanism of actual physical cleaning and priming of cleaning. After recalling moral transgression with strong feelings of guilt and shame, participants either actually cleaned their faces with or were primed with cleanliness through ...
March 8, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28338793/sensitivity-to-perception-level-differentiates-two-subnetworks-within-the-mirror-neuron-system
#18
Shiri Simon, Roy Mukamel
Mirror neurons are a subset of brain cells that discharge during action execution and passive observation of similar actions. An open question concerns the functional role of their ability to match observed and executed actions. Since understanding of goals requires conscious perception of actions, we expect that mirror neurons potentially involved in action goal coding, will be modulated by changes in action perception level. Here, we manipulated perception level of action videos depicting short hand movements and measured the corresponding fMRI BOLD responses in mirror regions...
February 17, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28338791/brains-in-dialogue-decoding-neural-preparation-of-speaking-to-a-conversational-partner
#19
Anna K Kuhlen, Carsten Bogler, Susan E Brennan, John-Dylan Haynes
In dialogue, language processing is adapted to the conversational partner. We hypothesize that the brain facilitates partner-adapted language processing through preparatory neural configurations (task sets) that are tailored to the conversational partner. In this experiment, we measured neural activity with functional magnetic resonance imaging (fMRI) while healthy participants in the scanner (a) engaged in a verbal communication task with a conversational partner outside of the scanner, or (b) spoke outside of a conversational context (to test the microphone)...
February 17, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28338783/empathy-and-moral-emotions-in-post-apartheid-south-africa-an-fmri-investigation
#20
Melike M Fourie, Dan J Stein, Mark Solms, Pumla Gobodo-Madikizela, Jean Decety
Moral emotions elicited in response to others' suffering are mediated by empathy and affect how we respond to their pain. South Africa provides a unique opportunity to study group processes given its racially divided past. The present study seeks insights into aspects of the moral brain by investigating behavioral and functional MRI responses of White and Black South Africans who lived through apartheid to in- and out-group physical and social pain. Whereas the physical pain task featured faces expressing dynamic suffering, the social pain task featured victims of apartheid violence from the South African Truth and Reconciliation Commission to elicit heartfelt emotion...
February 17, 2017: Social Cognitive and Affective Neuroscience
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