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https://www.readbyqxmd.com/read/28438349/hydrogen-bonds-in-the-vicinity-of-the-special-pair-of-the-bacterial-reaction-center-probed-by-hydrostatic-high-pressure-absorption-spectroscopy
#1
Liina Kangur, Michael R Jones, Arvi Freiberg
Using the native bacteriochlorophyll a pigment cofactors as local probes, we investigated the response to external hydrostatic high pressure of reaction center membrane protein complexes from the photosynthetic bacterium Rhodobacter sphaeroides. Wild-type and engineered complexes were used with a varied number (0, 1 or 2) of hydrogen bonds that bind the reaction center primary donor bacteriochlorophyll cofactors to the surrounding protein scaffold. A pressure-induced breakage of hydrogen bonds was established for both detergent-purified and membrane-embedded reaction centers, but at rather different pressures: between 0...
April 7, 2017: Biophysical Chemistry
https://www.readbyqxmd.com/read/28252630/-pharmacoepidemiological-study-of-the-course-of-influenza-and-other-acute-respiratory-viral-infections-in-risk-groups
#2
V A Bulgakova, A A Poromov, A I Grekova, N Yu Pshenichnaya, E P Selkova, N I Lvov, I A Leneva, I V Shestakova, V V Maleev
AIM: To identify risk factors (RFs) for the development of bacterial complications and the prolonged course of influenza and other acute respiratory viral infections (ARVIs) among inpatients treated in Russian healthcare facilities in the post-pandemic period; to determine the clinical presentation of the disease (flu-like syndrome) in risk-group people and to evaluate the efficacy of antiviral therapy with arbidol (umifenovir). MATERIAL AND METHODS: The investigators retrospectively analyzed randomly selected medical records of inpatients with influenza and other ARVI in 88 hospitals from 50 regions of the Russian Federation: those of 3532 and 1755 patients in the 2010-2011 and 2014-2015 seasons, respectively, by applying parametric and nonparametric statistical methods...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28105538/comparison-of-non-invasive-blood-pressure-monitoring-using-modified-arterial-applanation-tonometry-with-intra-arterial-measurement
#3
Jarkko Harju, Antti Vehkaoja, Pekka Kumpulainen, Stefano Campadello, Ville Lindroos, Arvi Yli-Hankala, Niku Oksala
Intermittent non-invasive blood pressure measurement with tourniquets is slow, can cause nerve and skin damage, and interferes with other measurements. Invasive measurement cannot be safely used in all conditions. Modified arterial tonometry may be an alternative for fast and continuous measurement. Our aim was to compare arterial tonometry sensor (BPro(®)) with invasive blood pressure measurement to clarify whether it could be utilized in the postoperative setting. 28 patients who underwent elective surgery requiring arterial cannulation were analyzed...
January 19, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28029350/-erratum-to-breast-cancer-screening-on-our-way-to-the-future-bull-cancer-103-2016-753-763
#4
Suzette Delaloge, Thomas Bachelot, François-Clément Bidard, Marc Espie, Etienne Brain, Hervé Bonnefoi, Joseph Gligorov, Florence Dalenc, Anne-Claire Hardy-Bessard, David Azria, Jean-Philippe Jacquin, Jérôme Lemonnier, William Jacot, Anthony Goncalves, Charles Coutant, Gérard Ganem, Thierry Petit, Frédérique Penault-Llorca, Marc Debled, Mario Campone, Christelle Levy, Bruno Coudert, Alain Lortholary, Laurence Venat-Bouvet, Julien Grenier, Hugues Bourgeois, Bernard Asselain, Johanna Arvis, Martine Castro, Anne Tardivon, David G Cox, Patrick Arveux, Corinne Balleyguier, Fabrice André, Roman Rouzier
No abstract text is available yet for this article.
October 28, 2016: Bulletin du Cancer
https://www.readbyqxmd.com/read/28012082/assessment-of-multi-contaminant-exposure-in-a-cancer-treatment-center-a-2-year-monitoring-of-molds-mycotoxins-endotoxins-and-glucans-in-bioaerosols
#5
Natacha Heutte, Véronique André, Catherine Dubos Arvis, Valérie Bouchart, Françoise Lemarié, Patrick Legendre, Edwige Votier, Marie-Yolande Louis, Stéphane Madelaine, Virginie Séguin, Stéphanie Gente, Philippe Vérité, David Garon
Indoor air quality in health care facilities is a major public health concern, particularly for immunocompromised patients who may be exposed to microbiological contaminants such as molds, mycotoxins, endotoxins, and (1,3)-ß-D-glucans. Over 2 years, bioaerosols were collected on a monthly basis in a cancer treatment center (Centre F. Baclesse, Normandy, France), characterized from areas where there was no any particular air treatment. Results showed the complexity of mycoflora in bioaerosols with more than 100 fungal species identified...
January 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28005035/-acute-respiratory-viral-infections-topical-issues-of-diagnosis-prevention-and-treatment-in-therapeutic-practice
#6
D I Trukhan, A L Mazurov, L A Rechapova
AIM: to assess the efficacy and safety of the medication Grippferon with loratadine for the prevention of acute respiratory viral infections (ARVI) and influenza during the epidemics. MATERIAL AND METHODS: This study included 103 patients (67 men and 36 women) aged 18 to 52 years (mean age 35.3±3.2 years). During the first visit (september 2015), we collected patient history data on the average rate of ARVI and influenza for the past three years, the disease duration and its symptoms, presence of concomitant allergic pathologies (such as vasomotor rhinitis, hay fever and urticaria) and food allergies...
2016: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28005034/-treatment-for-acute-respiratory-viral-infection-and-influenza-in-daily-clinical-practice-results-of-the-multicenter-international-observational-flu-ee-study
#7
V Kh Fazylov, I G Sitnikov, E V Silina, S B Shevchenko, L N Mozhina, L L Zamyatina, G A Eganyan, L G Groppa, B M Korsantiya
PURPOSE: To study the clinical aspects of influenza and acute respiratory viral infection (ARVI) in routine clinical practice, with efficacy and safety of the antiviral therapy evaluation. SUBJECTS AND METHODS: In the large multicenter prospective observational study were enrolled 18,946 patients aged 18 to 93 years with previously determined diagnosis of influenza or ARVI from 262 outpatient sites in Russia, Armenia, Moldova and Georgia. According to study design, 3 visits were evaluated...
2016: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/27970741/long-term-outcome-of-couples-undertaking-their-first-ivf-icsi-attempt-a-french-study
#8
I Parneix, P Arvis, S Paillet, J Longin, P Lehert, C Avril, F Lesourd
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27752932/determination-of-saturation-heart-rate-and-respiratory-rate-at-forearm-using-a-nellcor%C3%A2-forehead-spo2-saturation-sensor
#9
Jarkko Harju, Antti Vehkaoja, Ville Lindroos, Pekka Kumpulainen, Sasu Liuhanen, Arvi Yli-Hankala, Niku Oksala
Alterations in arterial blood oxygen saturation, heart rate (HR), and respiratory rate (RR) are strongly associated with intra-hospital cardiac arrests and resuscitations. A wireless, easy-to-use, and comfortable method for monitoring these important clinical signs would be highly useful. We investigated whether the Nellcor™ OxiMask MAX-FAST forehead sensor could provide data for vital sign measurements when located at the distal forearm instead of its intended location at the forehead to provide improved comfortability and easy placement...
October 17, 2016: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/27699474/atlas-of-human-diseases-influenced-by-genetic-variants-with-extreme-allele-frequency-differences
#10
Arvis Sulovari, Yolanda H Chen, James J Hudziak, Dawei Li
Genetic variants with extreme allele frequency differences (EAFD) may underlie some human health disparities across populations. To identify EAFD loci, we systematically analyzed and characterized 81 million genomic variants from 2504 unrelated individuals of 26 world populations (phase III of the 1000 Genomes Project). Our analyses revealed a total of 434 genes, 15 pathways, and 18 diseases and traits influenced by EAFD variants from five continental populations. They included known EAFD genes, such as LCT (lactose tolerance), SLC24A5 (skin pigmentation), and EDAR (hair morphology)...
October 3, 2016: Human Genetics
https://www.readbyqxmd.com/read/27676575/p2-41-also-presented-as-pd1-06-pembrolizumab-vs-docetaxel-for-previously-treated-nsclc-keynote-010-archival-vs-new-tumor%C3%A2-samples-for-pd-l1-assessment-track-immunotherapy
#11
Roy S Herbst, Paul Baas, Jose L Perez-Gracia, Enriqueta Felip, Dong-Wan Kim, Ji-Youn Han, Julian Molina, Joo-Hang Kim, Catherine Dubos Arvis, Myung-Ju Ahn, Margarita Majem, Mary Jo Fidler, Veerle Surmont, Gilberto De Castro, Marcelo Garrido, Yue Shentu, Marisa Dolled-Filhart, Ellie Im, Edward B Garon
No abstract text is available yet for this article.
October 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27676480/pd1-06-also-presented-as-p2-41-pembrolizumab-vs-docetaxel-for-previously-treated-nsclc-keynote-010-archival-vs-new-tumor%C3%A2-samples-for-pd-l1-assessment
#12
Roy S Herbst, Paul Baas, Jose L Perez-Gracia, Enriqueta Felip, Dong-Wan Kim, Ji-Youn Han, Julian Molina, Joo-Hang Kim, Catherine Dubos Arvis, Myung-Ju Ahn, Margarita Majem, Mary Jo Fidler, Veerle Surmont, Gilberto De Castro, Marcelo Garrido, Yue Shentu, Marisa Dolled-Filhart, Ellie Im, Edward B Garon
No abstract text is available yet for this article.
October 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27514285/spectral-and-kinetic-effects-accompanying-the-assembly-of-core-complexes-of-rhodobacter-sphaeroides
#13
Arvi Freiberg, Manoop Chenchiliyan, Margus Rätsep, Kõu Timpmann
In the present work, spectral and kinetic changes accompanying the assembly of the light-harvesting 1 (LH1) complex with the reaction center (RC) complex into monomeric RC-LH1 and dimeric RC-LH1-PufX core complexes of the photosynthetic purple bacterium Rhodobacter sphaeroides are systematically studied over the temperature range of 4.5-300K. The samples were interrogated with a combination of optical absorption, hole burning, fluorescence excitation, steady state and picosecond time resolved fluorescence spectroscopy...
November 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27492427/detection-of-spine-structures-with-bioimpedance-probe-bip-needle-in-clinical-lumbar-punctures
#14
Sanna Halonen, Kari Annala, Juho Kari, Samuli Jokinen, Aki Lumme, Kai Kronström, Arvi Yli-Hankala
Lumbar puncture is a relatively safe procedure, but some serious, even fatal, complications can occur. Needle guidance can increase puncture accuracy, decrease the number of attempts, and make the procedure easier. We tested the feasibility of a bioimpedance-based tissue-sensing technology for needle guidance in clinical use. The Bioimpedance Probe (BIP) Needle has a removable BIP stylet enabling measurement of bioimpedance spectra during the procedure. The BIP Needle is connected to a measurement device that uses tissue-classification software, and the device provides audiovisual feedback when it detects cerebrospinal fluid (CSF)...
August 4, 2016: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/27473920/-breast-cancer-screening-on-our-way-to-the-future
#15
REVIEW
Suzette Delaloge, Thomas Bachelot, François-Clément Bidard, Marc Espie, Etienne Brain, Hervé Bonnefoi, Joseph Gligorov, Florence Dalenc, Anne-Claire Hardy-Bessard, David Azria, Jean-Philippe Jacquin, Jérôme Lemonnier, William Jacot, Anthony Goncalves, Charles Coutant, Gérard Ganem, Thierry Petit, Frédérique Penault-Lorca, Marc Debled, Mario Campone, Christelle Levy, Bruno Coudert, Alain Lortholary, Laurence Venat-Bouvet, Julien Grenier, Hugues Bourgeois, Bernard Asselain, Johanna Arvis, Martine Castro, Anne Tardivon, David G Cox, Patrick Arveux, Corinne Balleyguier, Fabrice André, Roman Rouzier
Breast cancer remains a potentially lethal disease, which requires aggressive treatments and is associated with long-term consequences. Its prognosis is linked to both tumor biology and burden at diagnosis. Although treatments have allowed important improvements in prognosis over the past 20 years, breast cancer screening remains necessary. Mammographic screening allows earlier stage diagnoses and a decrease of breast cancer specific mortality. However, breast cancer screening modalities should be revised with the objective to address demonstrated limitations of mammographic screening (limited benefit, imperfect sensitivity and specificity, overdiagnoses, radiation-induced morbidity)...
September 2016: Bulletin du Cancer
https://www.readbyqxmd.com/read/27375597/phylogenomic-study-of-burkholderia-glathei-like-organisms-proposal-of-13-novel-burkholderia-species-and-emended-descriptions-of-burkholderia-sordidicola-burkholderia-zhejiangensis-and-burkholderia-grimmiae
#16
Charlotte Peeters, Jan P Meier-Kolthoff, Bart Verheyde, Evie De Brandt, Vaughn S Cooper, Peter Vandamme
Partial gyrB gene sequence analysis of 17 isolates from human and environmental sources revealed 13 clusters of strains and identified them as Burkholderia glathei clade (BGC) bacteria. The taxonomic status of these clusters was examined by whole-genome sequence analysis, determination of the G+C content, whole-cell fatty acid analysis and biochemical characterization. The whole-genome sequence-based phylogeny was assessed using the Genome Blast Distance Phylogeny (GBDP) method and an extended multilocus sequence analysis (MLSA) approach...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27372198/challenges-facing-an-understanding-of-the-nature-of-low-energy-excited-states-in-photosynthesis
#17
REVIEW
Jeffrey R Reimers, Malgorzata Biczysko, Douglas Bruce, David F Coker, Terry J Frankcombe, Hideki Hashimoto, Jürgen Hauer, Ryszard Jankowiak, Tobias Kramer, Juha Linnanto, Fikret Mamedov, Frank Müh, Margus Rätsep, Thomas Renger, Stenbjörn Styring, Jian Wan, Zhuan Wang, Zheng-Yu Wang-Otomo, Yu-Xiang Weng, Chunhong Yang, Jian-Ping Zhang, Arvi Freiberg, Elmars Krausz
While the majority of the photochemical states and pathways related to the biological capture of solar energy are now well understood and provide paradigms for artificial device design, additional low-energy states have been discovered in many systems with obscure origins and significance. However, as low-energy states are naively expected to be critical to function, these observations pose important challenges. A review of known properties of low energy states covering eight photochemical systems, and options for their interpretation, are presented...
September 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27285458/characterization-of-three-different-unusual-s-layer-proteins-from-viridibacillus-arvi-jg-b58-that-exhibits-two-super-imposed-s-layer-proteins
#18
Matthias Suhr, Franziska L Lederer, Tobias J Günther, Johannes Raff, Katrin Pollmann
Genomic analyses of Viridibacillus arvi JG-B58 that was previously isolated from heavy metal contaminated environment identified three different putative surface layer (S-layer) protein genes namely slp1, slp2, and slp3. All three genes are expressed during cultivation. At least two of the V. arvi JG-B58 S-layer proteins were visualized on the surface of living cells via atomic force microscopy (AFM). These S-layer proteins form a double layer with p4 symmetry. The S-layer proteins were isolated from the cells using two different methods...
2016: PloS One
https://www.readbyqxmd.com/read/27245618/improved-cognitive-flexibility-after-aortic-valve-replacement-surgery
#19
Jonne Liimatainen, Jari Peräkylä, Kati Järvelä, Tero Sisto, Arvi Yli-Hankala, Kaisa M Hartikainen
OBJECTIVES: Aortic valve replacement (AVR) surgery is associated with potential risk to cerebral injury. On the other hand, improved cardiovascular functioning after the surgery may have positive impact on brain health. The aim of this preliminary study was to investigate the impact of AVR surgery on cognition, specifically on higher cognitive control functions, i.e. executive functions, that are typically implicated in cognitive decline due to vascular origin. METHODS: Patients (n = 16) undergoing elective AVR surgery due to aortic stenosis were recruited and their cognitive performance was assessed using a computer-based Executive Reaction Time (RT) test...
October 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27130216/pre-hospital-severe-traumatic-brain-injury-comparison-of-outcome-in-paramedic-versus-physician-staffed-emergency-medical-services
#20
RANDOMIZED CONTROLLED TRIAL
Toni Pakkanen, Ilkka Virkkunen, Antti Kämäräinen, Heini Huhtala, Tom Silfvast, Janne Virta, Tarja Randell, Arvi Yli-Hankala
BACKGROUND: Traumatic brain injury (TBI) is one of the leading causes of death and permanent disability. Emergency Medical Services (EMS) personnel are often the first healthcare providers attending patients with TBI. The level of available care varies, which may have an impact on the patient's outcome. The aim of this study was to evaluate mortality and neurological outcome of TBI patients in two regions with differently structured EMS systems. METHODS: A 6-year period (2005 - 2010) observational data on pre-hospital TBI management in paramedic-staffed EMS and physician-staffed EMS systems were retrospectively analysed...
April 29, 2016: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
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