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Infrared Imaging

Feng Yang, Jian Zhou, Hao Li, Fan Yang, Rongxin Xiao, Chongwei Chi, Jie Tian, Jun Wang
OBJECTIVES: Chylothorax is an infrequent but relatively serious complication after lung cancer surgery. Finding the leakage site and identifying the thoracic duct (TD) are the key points of surgical intervention for chylothorax. In this study, for the first time, we demonstrated near-infrared fluorescence imaging with indocyanine green (ICG) in video-assisted thoracoscopic surgery (VATS) intervention for chylothorax in humans. METHODS: This study included 4 patients diagnosed with chylothorax after lung cancer surgery who underwent VATS intervention; 0...
September 25, 2017: Interactive Cardiovascular and Thoracic Surgery
Vivienne C Greenstein, Jason Nunez, Winston Lee, Kaspar Schuerch, Brad Fortune, Stephen H Tsang, Rando Allikmets, Janet R Sparrow, Donald C Hood
Purpose: To compare morphologic changes on en face images derived from wide-field swept-source optical coherence tomography (ssOCT) to hypo- and hyperautofluorescent (hypoAF, hyperAF) areas on short-wavelength autofluorescence (SW-AF), and near-infrared (NIR)-AF in recessive Stargardt disease (STGD1). Methods: Wide-field ssOCT cube scans were obtained from 16 patients (16 eyes). Averaged B-scans and SW-AF images were obtained using Spectralis HRA+OCT. NIR-AF images were obtained from 6 eyes...
October 1, 2017: Investigative Ophthalmology & Visual Science
Wenda Zhang, Feiyan Liu, Chao Zhang, Jian-Guang Luo, Jun Luo, Wenying Yu, Lingyi Kong
Leucine aminopeptidase (LAP) is a kind of proteolytic enzymes and associated closely with pathogenesis of cancer and liver injury. Accurate detection of LAP activity with high sensitivity and selectivity is imperative to detect its distribution and dynamic changes for understanding LAP's function and early diagnosing the disease states. However, fluorescent detection of LAP in living systems is challenging. To data, rarely fluorescent probes have been reported for imaging LAP in vivo. In this study, a novel probe (TMN-Leu) was developed by conjugating a near-infrared dicyanoisophorone derivative fluorophore with LAP activatable L-leucine amide moiety for the first time...
October 19, 2017: Analytical Chemistry
Chang Liu, Christoph Straif, Thomas Flügel-Paul, Uwe D Zeitner, Herbert Gross
Hyperspectral-grating-based imaging spectrometer systems with F/3 and covering the visual-near-infrared (420-1000 nm) spectral range are investigated for monitoring Earth's environmental changes. The systems have an entrance slit of 24 μm and a 6.5 nm spectral resolution. Both smile and keystone distortions are smaller than 20% of the pixel pitch. We benefit from the development in freeform technology and design 15 different systems with the help of off-axis aspheric and freeform surfaces. The potential of each system is explored with the help of nonspherical surfaces...
August 20, 2017: Applied Optics
Rang Liu, Dejiang Wang, Dabiao Zhou, Ping Jia
The research on optical imaging characteristics of infrared dim point targets in the presence of nonstationary cloud clutter and random noise is necessary for target detection. We analyze the energy concentration of point targets that are less than 3×3 pixels in size and deduce a simulation model of the point target imaging process. Then we adopt omnidirectional multiscale structural elements to detect all the possible targets distributing in every direction. The adaptive threshold and the energy concentration criterion are employed to eliminate false alarms...
August 20, 2017: Applied Optics
Francisco J Burgos-Fernández, Meritxell Vilaseca, Esther Perales, Elísabet Chorro, Francisco M Martínez-Verdú, José Fernández-Dorado, Jaume Pujol
In this study, a novel gonio-hyperspectral imaging system based on light-emitting diodes for the analysis of automotive coatings was validated colorimetrically and spectrally from 368 to 1309 nm. A total of 30 pearlescent, 30 metallic, and 30 solid real automotive coatings were evaluated with this system, the BYK-mac and X-Rite MA98 gonio-spectrophotometers, and also with the SPECTRO 320 spectrometer for further comparison. The results showed very precise correlations, especially in the visible range. In conclusion, this new system provides a deeper assessment of goniochromatic pigments than current approaches due to the expansion of the spectral range to the infrared...
September 1, 2017: Applied Optics
Aoi Takahashi, Keigo Enya, Kanae Haze, Hirokazu Kataza, Takayuki Kotani, Hideo Matsuhara, Tomohiro Kamiya, Tomoyasu Yamamuro, Paul Bierden, Steven Cornelissen, Charlie Lam, Michael Feinberg
This paper demonstrates a cryogenic deformable mirror (DM) with 1020 actuators based on micro-electrical mechanical systems (MEMS) technology. Cryogenic space-borne infrared telescopes can experience a wavefront error due to a figure error of their mirror surface, which makes the imaging performance worse. For on-orbit wavefront correction as one solution, we developed a MEMS-processed electro-static DM with a special surrounding structure for use under the cryogenic temperature. We conducted a laboratory demonstration of its operation in three cooling cycles between 5 K and 295 K...
August 10, 2017: Applied Optics
J-M Ortega, F Glotin, R Prazeres, X Li, R Gref
The purpose of this study is to extend the spectral range of a differential method of infrared micro-spectroscopy in order to allow the accurate detection of nanoparticles of interest for biomedical applications. Among these, metal-organic framework (MOF) nanoparticles have attracted increasing interest due to their capacity to incorporate high drug payloads, biodegradability, and possibility of tailoring their surfaces by grafting specific ligands. However, MOF particle detection in biological media without grafting or incorporating fluorescent molecules is challenging...
August 10, 2017: Applied Optics
Paul S Hsu, Daniel Lauriola, Naibo Jiang, Joseph D Miller, James R Gord, Sukesh Roy
A fiber-coupled, hyperspectral imaging sensor (HSIS) ranging from ultraviolet (UV) to short-wavelength-infrared (SWIR) wavelengths is developed for remote detection of planar [two-dimensional (2D)], spectrally resolved flame emission. The key component of the sensor is a dimension-reduction 2D-to-1D (one-dimensional) fiber-optic array that contains 1024 fibers and features high-UV optical transmission (>30% transmission at 310-340 nm, >90% at 340-2000 nm), wide operational wavelengths (300-2400 nm), and a compact and robust design (full length <5  cm)...
July 20, 2017: Applied Optics
Junqiang Sun, Menghua Wang
An enhanced methodology of the standard on-orbit calibration of the day-night band (DNB) of the visible infrared imaging radiometer suite on board the Suomi National Polar-orbiting Partnership satellite is presented, specifically for the low-gain stage. The range of the "sweet spot" for the fully illuminated scans in the calibration events is expanded from 4° to 7.8° in order to increase the number of fully illuminated scans to 72, which then permits a complete calibration of the DNB to be carried out within one orbit for all 36 aggregated modes and the two mirror sides...
May 20, 2017: Applied Optics
Jens Buchmann, James Guggenheim, Edward Zhang, Chris Scharfenorth, Bastian Spannekrebs, Claus Villringer, Jan Laufer
A Fabry-Perot ultrasound sensor with nonhygroscopic dielectric mirrors made out of Ta2O5 and SiO2 for use in photoacoustic tomography is described. The sensor offers flat frequency response up to 36 MHz, low noise-equivalent pressure (70 Pa), and near-omnidirectional response up to 20 MHz as well as optical transparency for near-infrared illumination. A numerical model was developed to predict its frequency response, and the results were validated experimentally. An image of the human palm was acquired to demonstrate in vivo imaging capabilities...
June 10, 2017: Applied Optics
Lei Jing, Yao Wang, Huifu Zhao, Hongliang Ke, Xiaoxun Wang, Qun Gao
In order to meet the requirements of uniform illumination for optical palm/fingerprint instruments and overcome the shortcomings of the poor uniform illumination on the working plane of the optical palm/fingerprint prism, a novel secondary optical lens with a free-form surface, compact structure, and high uniformity is presented in this paper. The design of the secondary optical lens is based on emission properties of the near-infrared light-emitting diode (LED) and basic principles of non-imaging optics, especially considering the impact of the thickness of the prism in the design...
June 10, 2017: Applied Optics
Qijie Tian, Songtao Chang, Fengyun He, Zhou Li, Yanfeng Qiao
Internal stray radiation is a key factor that influences infrared imaging systems, and its suppression level is an important criterion to evaluate system performance, especially for cryogenic infrared imaging systems, which are highly sensitive to thermal sources. In order to achieve accurate measurement for internal stray radiation, an approach is proposed, which is based on radiometric calibration using a spherical mirror. First of all, the theory of spherical mirror design is introduced. Then, the calibration formula considering the integration time is presented...
June 10, 2017: Applied Optics
Jing Meng, Xiujin Chen, Yang Tian, Zhongfeng Li, Qingfeng Zheng
Imaging-guided photothermal therapy provides an attractive way to eliminate the risk of cancer. In this paper, we prepared a composite material by nanoscale metal-organic frames (NMOFs) and graphene oxide (GO) for the potential use of photothermal therapy (PTT) of tumor guided with magnetic resonance imaging (MRI). The NMOFs containing Fe3+ were prefabricated with an octahedral morphology by a solvothermal reaction, offering strong T2-weighted contrast in MRI. Then the NMOFs were decorated with GO nanosheets, which were good at photothermal function...
October 19, 2017: Chemistry: a European Journal
Thi Tuong Vy Phan, Nhat Quang Bui, Madhappan Santha Moorthy, Kang Dae Lee, Junghwan Oh
Multifunctional nano-platform for the combination of photo-based therapy and photoacoustic imaging (PAI) for cancer treatment has recently attracted much attention to nanotechnology development. In this study, we developed iron-platinum nanoparticles (FePt NPs) with the polypyrrole (PPy) coating as novel agents for combined photothermal therapy (PTT) and PAI. The obtained PPy-coated FePt NPs (FePt@PPy NPs) showed excellent biocompatibility, photothermal stability, and high near-infrared (NIR) absorbance for the combination of PTT and PAI...
October 18, 2017: Nanoscale Research Letters
Ki Su Kim, Yun Seop Kim, Kai Bao, Hideyuki Wada, Hak Soo Choi, Sei Kwang Hahn
BACKGROUND: The injection of botulinum toxin (BTX) to reduce facial wrinkles is one of the most frequently performed plastic surgery procedures. The biocompatible hydrogels are injected with BTX for effective tissue augmentation. However, it is difficult to determine the interval of injection for effective tissue augmentation. METHOD: BTX and hyaluronate (HA) hydrogels were labeled with zwitterionic (ZW) near-infrared (NIR) fluorophores and visualized for 3 weeks after injection to BALB/c nude mice...
2017: Biomaterials Research
Leila Gharibshahi, Elias Saion, Elham Gharibshahi, Abdul Halim Shaari, Khamirul Amin Matori
Very narrow and pure silver nanoparticles were synthesized by modified thermal treatment method via oxygen and nitrogen flow in succession. The structural and optical properties of the calcined silver nanoparticles at 600°C with diverse Poly(vinylpyrrolidone) concentrations varied from 2% to 4% were studied by means of different techniques. Fourier transform infrared spectroscopy was used to monitor the production of pure Ag nanoparticles at a given Poly(vinylpyrrolidone) concentration. The X-ray powder diffraction spectra are evidence for the transformation of the amorphous sample at 30°C to the cubic crystalline nanostructures at the calcination temperatures for all Poly(vinylpyrrolidone) concentrations...
2017: PloS One
Kemal Tuna Olğaç, Ergun Akçay, Beste Çil, Burak Mehmet Uçar, Ali Daşkın
BACKGROUND: The aim of the study is to evaluate the effectiveness of thermographic monitoring, using the temperature changes of perianal and perivulvar areas for the determination of estrus in Anatolian Shepherd bitches. Fifteen bitches were used in the study. Blood and vaginal smear samples were collected and thermographic monitoring of perianal and perivulvar areas were carried out starting from proestrus to early diestrus. Also, external signs of estrus were investigated. Smear samples were evaluated by light microscopy after Diff-Quik staining method and superficial and keratinized superficial cells were determined as percentage (S + KS%)...
2017: Journal of Animal Science and Technology
Xueling Mu, Chenglin Yan, Qiwei Tian, Jiaomin Lin, Shiping Yang
Protein-related nanotheranostic agents hold great promise as tools to serve many clinical applications. Proteins such as BSA are used to regulate the synthesis of nondegradable inorganic nanoparticles (NPs). To fully employ the potential of such proteins, a new type of biosafe nanotheranostic agent must be designed to optimize BSA as a biomineralization agent. Here, a straightforward BSA-assisted biomineralization method was developed to prepare gallic acid (GA)-Fe(III) coordination polymer NPs. BSA-coated GA-Fe (GA-Fe@BSA) NPs were ultrasmall (3...
2017: International Journal of Nanomedicine
Dan Liu, Xin Liu, Yan Zhang, Qisong Wang, Jingyang Lu, Jinwei Sun
Continuous-wave Near-Infrared (NIR) optical spectroscopy has shown great diagnostic capability in the early tumor detection with advantages of low-cost, portable, non-invasive, and non-radiative. In this paper, Modified Lambert-Beer Theory is deployed to address the low-resolution issues of the NIR technique and to design the tumor detecting and imaging system. Considering that tumor tissues have features such as high blood flow and hypoxia, the proposed technique can detect the location, size, and other information of the tumor tissues by comparing the absorbance between pathological and normal tissues...
October 17, 2017: Computer Assisted Surgery (Abingdon, England)
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