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https://www.readbyqxmd.com/read/28350570/low-density-lipoprotein-receptor-related-protein-4-positive-myasthenia-gravis-in-a-double-seronegative-electromyography-negative-patient
#1
Joshua M Kruger, Dimitrios Karussis, Paraskevi Zisimopoulou, Panayiota Petrou
We describe a patient with ocular myasthenia gravis, where single-fiber electromyography and testing for acetylcholine receptor and muscle-specific kinase antibodies were negative. However, antibodies to low-density lipoprotein receptor-related protein 4 (LRP4) were positive, and this prompted appropriate management. We recommend that testing for LRP4 antibodies be considered when the clinical suspicion for myasthenia gravis is high despite negative conventional diagnostic tests.
March 27, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28350466/wrapping-aligned-carbon-nanotube-composite-sheets-around-vanadium-nitride-nanowire-arrays-for-asymmetric-coaxial-fiber-shaped-supercapacitors-with-ultrahigh-energy-density
#2
Qichong Zhang, Xiaona Wang, Zhenghui Pan, Juan Sun, Jingxin Zhao, Jun Zhang, Cuixia Zhang, Lei Tang, Jie Luo, Bin Song, Zengxing Zhang, Weibang Lu, Qingwen Li, Yuegang Zhang, Yagang Yao
The emergence of fiber-shaped supercapacitors (FSSs) has led to a revolution in portable and wearable electronic devices. However, obtaining high energy density FSSs for practical applications is still a key challenge. This article exhibits a facile and effective approach to directly growth well-aligned three-dimensional vanadium nitride (VN) nanowire arrays (NWAs) on carbon nanotube (CNT) fiber with an ultrahigh specific capacitance of 715 mF/cm2 in a three-electrode system. Benefiting from their intriguing structural features, we successfully fabricated a prototype asymmetric coaxial FSS (ACFSS) with a maximum operating voltage of 1...
March 28, 2017: Nano Letters
https://www.readbyqxmd.com/read/28350452/velcro%C3%A2-inspired-sic-fuzzy-fibers-for-aerospace-applications
#3
Amelia H C Hart, Ryota Koizumi, John T Hamel, Peter Samora Owuor, Yusuke Ito, Sehmus Ozden, Sanjit Bhowmick, Syed Asif Syed Amanulla, Thierry Tsafack, Kunttal Keyshar, Rahul Mital, Janet Hurst, Robert Vajtai, Chandra Sekhar Tiwary, Pulickel M Ajayan
The most recent and innovative silicon carbide (SiC) Fiber-SiC ceramic matrix composites, used for light-weight high-heat engine parts in aerospace applications, are woven, layered, then surrounded by a SiC ceramic matrix composite (CMC). To further improve both the mechanical properties and thermal and oxidative resistance abilities of this material, SiC nanotubes and nanowires (SiCNT/NWs) are grown on the surface of the SiC fiber via carbon nanotube conversion. This conversion utilizes the shape memory synthesis (SMS) method, starting with carbon nanotube (CNT) growth on the SiC fiber surface, to capitalize on the ease of dense surface morphology optimization and the ability to effectively engineer the CNT-SiC fiber interface to create a secure nanotube-fiber attachment...
March 28, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28346861/biomimetic-remineralization-of-carious-lesions-by-self-assembling-peptide
#4
L Kind, S Stevanovic, S Wuttig, S Wimberger, J Hofer, B Müller, U Pieles
Caries is the most common disease in the world. Great efforts have been undertaken for prevention and to identify a regenerative treatment solution for dental caries. Self-assembling β-sheet forming peptides have previously shown to form 3-dimensional fiber networks supporting tissue regeneration. In particular, the self-assembling peptide P11-4 has shown potential in the treatment and prevention of dental caries. It has previously been shown that application of monomeric P11-4 solution to early carious lesions can increase net mineral gain by forming de novo hydroxyapatite crystals...
March 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28346782/%C3%AE%C2%BA-carrageenan-enhances-the-biomineralization-and-osteogenic-differentiation-of-electrospun-phb-and-phbv-fibers
#5
Nowsheen Goonoo, Behnam Khanbabaee, Marc Steuber, Archana Bhaw-Luximon, Ulrich Jonas, Ullrich Pietsch, Dhanjay Jhurry, Holger Schönherr
Novel electrospun materials for bone tissue engineering were obtained by blending biodegradable polyhydroxybutyrate (PHB) or polyhydroxybutyrate valerate (PHBV) with the anionic sulfated polysaccharide κ-carrageenan (κ-CG) in varying ratios. In both systems, the two components phase separated as shown by FTIR, DSC and TGA. According to the contact angle data, κ-CG was localized preferentially at the fiber surface in PHBV/ κ-CG blends in contrast to PHB/ κ-CG, where the biopolymer was mostly found within the fiber...
March 27, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28346744/radiopaque-uhmwpe-sublaminar-cables-for-spinal-deformity-correction-preclinical-mechanical-and-radiopacifier-leaching-assessment
#6
Alex K Roth, Karlien Boon-Ceelen, Harold Smelt, Bert van Rietbergen, Paul C Willems, Lodewijk W van Rhijn, Jacobus J Arts
Polymeric sublaminar cables have a number of advantages over metal cables in the field of spinal deformity surgery, with decreased risk of neurological injury and potential for higher correction forces as the two most predominant. However, currently available polymer cables are radiolucent, precluding postoperative radiological assessment of instrumentation stability and integrity. This study provides a preclinical assessment of a woven UHMWPE cable made with radiopaque UHMWPE fibers. Our primary goal was to determine if the addition of a radiopacifier negatively affects the mechanical properties of UHMWPE woven cables...
March 27, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28346743/fabrication-of-a-mechanically-anisotropic-poly-glycerol-sebacate-membrane-for-tissue-engineering
#7
Chi-Nung Hsu, Pei-Yuan Lee, Ho-Yi Tuan-Mu, Chen-Yu Li, Jin-Jia Hu
Poly(glycerol sebacate) (PGS) has been used successfully as a scaffolding material for soft tissue engineering. PGS scaffolds, however, are usually mechanically isotropic, which may restrict their use in tissue repairs as many soft tissues in the body have anisotropic mechanical behaviors. Although various methods have been used to fabricate anisotropic scaffolds, it remains challenging to make anisotropic scaffolds from thermoset PGS. Here a new, simple method to fabricate an anisotropic PGS membrane which can then be used to construct thicker three-dimensional anisotropic scaffolds was developed...
March 27, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28346392/impact-of-novel-sorghum-bran-diets-on-dss-induced-colitis
#8
Lauren E Ritchie, Stella S Taddeo, Brad R Weeks, Raymond J Carroll, Linda Dykes, Lloyd W Rooney, Nancy D Turner
We have demonstrated that polyphenol-rich sorghum bran diets alter fecal microbiota; however, little is known regarding their effect on colon inflammation. Our aim was to characterize the effect of sorghum bran diets on intestinal homeostasis during dextran sodium sulfate (DSS)-induced colitis. Male Sprague-Dawley rats (N = 20/diet) were provided diets containing 6% fiber from cellulose, or Black (3-deoxyanthocyanins), Sumac (condensed tannins) or Hi Tannin Black (both) sorghum bran. Colitis was induced (N = 10/diet) with three separate 48-h exposures to 3% DSS, and feces were collected...
March 27, 2017: Nutrients
https://www.readbyqxmd.com/read/28346279/sub-basal-corneal-nerve-plexus-analysis-using-a-new-software-technology
#9
Hatim Batawi, Nabeel Shalabi, Madhura Joag, Tulay Koru-Sengul, Jorge Rodriguez, Parke T Green, Mauro Campigotto, Carol L Karp, Anat Galor
PURPOSE: To study sub-basal corneal nerve plexus (SCNP) parameters by in vivo corneal confocal microscopy using a new software technology and examine the effect of demographics and diabetes mellitus (DM) on corneal nerves morphology. METHODS: A Confoscan 4 (Nidek Technologies) was used in this cross-sectional study to image the SCNP in 84 right eyes at the Miami Veterans Affairs eye clinic. Images were analyzed using a new semiautomated nerve analysis software program (The Corneal Nerve Analysis tool) which evaluated 9 parameters including nerve fibers length (NFL) and nerve fibers length density (NFLD)...
March 24, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28346061/understanding-the-contamination-of-food-with-mineral-oil-the-need-for-a-confirmatory-analytical-and-procedural-approach
#10
Lionel W Spack, Gabriela Leszczyk, Jesus Varela, Hervé Simian, Thomas Gude, Richard H Stadler
The contamination of food by mineral oil hydrocarbons (MOH) found in packaging is a long running concern. A main source of MOH in foods is the migration of mineral oil from recycled board into the packed food products. Consequently, the majority of food manufacturers have taken protective measures, for example by using virgin board instead of recycled fibers, and where feasible, introducing functional barriers to mitigate migration. Despite these protective measures, MOH may still be observed at low amounts in certain food products, albeit due to different entry points across the food supply chain...
March 27, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/28345919/photocontrol-of-clustering-retaining-and-releasing-of-microbeads-concomitant-with-phototransformation-of-supramolecular-architecture-of-amphiphilic-diarylethene
#11
Akira Sakaguchi, Kenji Higashiguchi, Hajime Yotsuji, Kenji Matsuda
Photoinduced clustering of polystyrene microbeads and photocontrol of their diffusion was achieved in water with the assistance of photoinduced transformation of supramolecular architecture of amphiphilic diarylethene between sphere and fiber states. When a suspension of polystyrene beads containing the sphere state of diarylethene was UV-irradiated from beneath, clustering of the polystyrene beads by thermal convection was observed. The velocity of clustering was dependent on the amount of photogenerated nanofibers that determines the viscosity of the water...
March 27, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28345872/intrinsically-stretchable-and-conductive-textile-by-a-scalable-process-for-elastic-wearable-electronics
#12
Chunya Wang, Mingchao Zhang, Kailun Xia, Xueqin Gong, Huimin Wang, Zhe Yin, Baolu Guan, Yingying Zhang
The prosperous development of stretchable electronics poses great demand in stretchable conductive materials which could maintain their electrical conductivity under tensile strain. Previously reported strategies to obtain stretchable conductors usually involve complex structure-fabricating processes or utilization of high-cost nanomaterials. It remains a great challenge to produce stretchable and conductive materials via a scalable and cost-effective process. A large-scalable pyrolysis strategy is developed for the fabrication of intrinsically stretchable and conductive textile utilizing low-cost and mass-produced weft-knitted textiles as raw materials...
March 27, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28345756/the-dawn-of-dentistry-in-the-late-upper-paleolithic-an-early-case-of-pathological-intervention-at-riparo-fredian
#13
Gregorio Oxilia, Flavia Fiorillo, Francesco Boschin, Elisabetta Boaretto, Salvatore A Apicella, Chiara Matteucci, Daniele Panetta, Rossella Pistocchi, Franca Guerrini, Cristiana Margherita, Massimo Andretta, Rita Sorrentino, Giovanni Boschian, Simona Arrighi, Irene Dori, Giuseppe Mancuso, Jacopo Crezzini, Alessandro Riga, Maria C Serrangeli, Antonino Vazzana, Piero A Salvadori, Mariangela Vandini, Carlo Tozzi, Adriana Moroni, Robin N M Feeney, John C Willman, Jacopo Moggi-Cecchi, Stefano Benazzi
OBJECTIVES: Early evidence for the treatment of dental pathology is found primarily among food-producing societies associated with high levels of oral pathology. However, some Late Pleistocene hunter-gatherers show extensive oral pathology, suggesting that experimentation with therapeutic dental interventions may have greater antiquity. Here, we report the second earliest probable evidence for dentistry in a Late Upper Paleolithic hunter-gatherer recovered from Riparo Fredian (Tuscany, Italy)...
March 27, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28345535/photoactivated-processes-in-optical-fibers-generation-and-conversion-mechanisms-of-twofold-coordinated-si-and-ge-atoms
#14
Luigi Giacomazzi, Layla Martin-Samos, Aziz Boukenter, Youcef Ouerdane, Sylvain Girard, Antonino Alessi, Nicolas Richard, Stefano de Gironcoli
In this work we present an extensive investigation of nanoscale physical phenomena related to oxygen-deficient centers (ODC) in silica and Ge-doped silica by means of first-principles calculations, including nudged-elastic band (NEB), electron paramagnetic resonance (EPR) parameters calculations, and many-body perturbation theory (GW and Bethe-Salpeter Equation) techniques. We show that by neutralizing positively charged oxygen monovacancies we can obtain model structures of twofold Si and Ge defects of which the calculated absorption spectra and singlet-to-triplet transitions are in excellent agreement with the experimental optical absorption and photo-luminescence data...
March 27, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28345418/a-coaxial-dual-element-focused-ultrasound-probe-for-guidance-of-epidural-catheterization
#15
Guo-Chung Dong, Li-Chen Chiu, Chien-Kun Ting, Jia-Ruei Hsu, Chih-Chung Huang, Yin Chang, Gin-Shin Chen
Ultrasound guidance for epidural block has improved clinical blind-trial problems but the design of present ultrasonic probes poses operating difficulty of ultrasound-guided catheterization, increasing the failure rate. The purpose of this study was to develop a novel ultrasonic probe to avoid needle contact with vertebral bone during epidural catheterization. The probe has a central circular passage for needle insertion. Two focused annular transducers are deployed around the passage for on-axis guidance. A 17-gauge insulated Tuohy needle containing the self-developed fiber-optic-modified stylet was inserted into the back of the anesthetized pig, in the lumbar region under the guidance of our ultrasonic probe...
March 1, 2017: Ultrasonic Imaging
https://www.readbyqxmd.com/read/28345417/the-effect-of-mechanical-loading-upon-extracellular-matrix-bioscaffold-mediated-skeletal-muscle-remodeling
#16
Jenna Lynn Dziki, Ross M Giglio, Brian M Sicari, Derek S Wang, Riddhi M Gandhi, Ricardo Londono, Christopher L Dearth, Stephen F Badylak
Mounting evidence suggests that site-appropriate loading of implanted extracellular matrix (ECM) bioscaffolds and the surrounding microenvironment is an important tissue remodeling determinant, though the role at the cellular level in ECM-mediated skeletal muscle remodeling remains unknown. The present study evaluates cross-talk between progenitor cells and macrophages during mechanical loading in ECM-mediated skeletal muscle repair. Myoblasts were exposed to solubilized ECM bioscaffolds and were mechanically loaded at 10% strain, 1 Hz for 5 hours...
March 27, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28345407/knee-menisci
#17
James Kevin Bryceland, Andrew John Powell, Thomas Nunn
The menisci of the knees are semicircular fibrocartilaginous structures consisting of a hydrophilic extracellular matrix containing a network of collagen fibers, glycoproteins, and proteoglycans maintained by a cellular component. The menisci are responsible for more than 50% of load transmission across the knee and increase joint congruity thereby also aiding in fluid film lubrication of the joint. In the United Kingdom, meniscal tears are the most common form of intra-articular knee injury and one of the commonest indications for orthopedic intervention...
April 2017: Cartilage
https://www.readbyqxmd.com/read/28345354/optimization-of-mold-wheat-bread-fortified-with-soy-flour-pea-flour-and-whey-protein-concentrate
#18
Melina Erben, Carlos A Osella
The objective of this work was to study the effect of replacing a selected wheat flour for defatted soy flour, pea flour and whey protein concentrate on both dough rheological characteristics and the performance and nutritional quality of bread. A mixture design was used to analyze the combination of the ingredients. The optimization process suggested that a mixture containing 88.8% of wheat flour, 8.2% of defatted soy flour, 0.0% of pea flour and 3.0% of whey protein concentrate could be a good combination to achieve the best fortified-bread nutritional quality...
January 1, 2017: Food Science and Technology International, Ciencia y Tecnología de Los Alimentos Internacional
https://www.readbyqxmd.com/read/28345221/the-effect-of-the-timing-of-electromyostimulation-on-denervated-skeletal-muscle-atrophy
#19
Eun Sil Koh, Hee Chan Kim, Jae-Young Lim
INTRODUCTION: We evaluated the effect of electromyostimulation (EMS) on myosin heavy chain (MHC) isoform expression in denervated muscles to determine the optimal timing for EMS application. METHODS: EMS was initiated on post-injury Day 1 for the group with denervation receiving immediate EMS (DIEMS) and on post-injury Day 15 for the group with denervation receiving delayed EMS (DDEMS) in rat denervated muscles. Muscle wet weight and muscle fiber cross-sectional area (FCSA) were measured...
March 27, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28345095/a-simple-functional-carbon-nanotube-fiber-for-in-vivo-monitoring-of-no-in-a-rat-brain-following-cerebral-ischemia
#20
Li Liu, Limin Zhang, Zhihui Dai, Yang Tian
Nitric oxide (NO) is key free-radical messenger and neuronal signal which is closely related to many brain diseases. It is a challenge to develop a sensitive and reliable biosensor for in vivo monitoring of NO in the brain. In this research, a simple ratiometric electrochemical biosensor for NO monitoring in rat brain following cerebral ischemia was developed using a carbon nanotube fiber (CNF) modified with hemin, in which the CNF not only served as a platform to assemble the hemin molecule, but greatly facilitated the electron transfer of hemin on to the electrode surface...
March 27, 2017: Analyst
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