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https://www.readbyqxmd.com/read/27746875/angiosarcoma-a-case-report-of-gingival-disease-with-both-palatine-tonsils-localization
#1
Frédéric Chamberland, Tristan Maurina, Séverine Degano-Valmary, Thierry Spicarolen, Loïc Chaigneau
Angiosarcomas are one of the rarest subtypes of sarcomas; those are malignant vascular tumors arising from vascular endothelial cells. Occurrence of intra-oral angiosarcoma is extremely rare (0.0077% of all cancers in Europe). We present here, to our knowledge, the first case of a 83-year-old man with gingival and both palatine tonsils localization of a grade-two angiosarcoma discovered after a two months history of a painful lesion followed by hematoma and spontaneous bleeding. Chemotherapy with paclitaxel and hemostatic radiotherapy were inefficient and he died seven months after the first symptoms...
September 5, 2016: Rare Tumors
https://www.readbyqxmd.com/read/27714941/bevacizumab-for-non-small-cell-lung-cancer-a-nested-case-control-study-of-risk-factors-for-hemoptysis
#2
Koichi Goto, Masahiro Endo, Masahiko Kusumoto, Nobuyuki Yamamoto, Yuichiro Ohe, Ayaka Shimizu, Masahiro Fukuoka
Potentially life-threatening, serious hemoptysis is an adverse event associated with bevacizumab in non-squamous non-small-cell lung cancer (NSCLC) trials. Suggested risk factors include central tumor location and cavitation; however, the profile of hemoptysis occurrence in clinical practice is still unclear. A nested case-control study was conducted to assess the onset profile and risk factors for hemoptysis in bevacizumab-treated patients in a real-world setting in Japan. After bevacizumab was approved for NSCLC, Physicians registered all NSCLC patients scheduled for bevacizumab therapy, from November 2009 to August 2011...
October 6, 2016: Cancer Science
https://www.readbyqxmd.com/read/27138958/preoperative-chemoradiotherapy-for-rectal-cancer-in-patients-aged-75-years-and-older-acute-toxicity-compliance-with-treatment-and-early-results
#3
Valentine Guimas, Jihane Boustani, Benjamin Schipman, Nicolas Lescut, Marc Puyraveau, Jean François Bosset, Stéphanie Servagi-Vernat
PURPOSE: Treatment of locally advanced rectal cancer (T3-T4 or N+) is based on short-course radiotherapy (RT) or chemoradiotherapy (CRT) followed by surgery. It is estimated that 30-40 % of rectal cancer occurs in patients aged 75 years or more. Data on adherence to neoadjuvant CRT and its safety remain poor owing to the under-representation of older patients in randomized clinical trials and the discordance in the results from retrospective studies. The aim of this study was to assess adherence with preoperative CRT and tolerability in older patients with a stage II/III unresectable rectal cancer...
June 2016: Drugs & Aging
https://www.readbyqxmd.com/read/26748843/microcytic-carcinoma-of-the-urinary-bladder-experience-over-22-years
#4
G Velilla, C J Carrión, J A Portillo, D Truán, A Azueta, J Fuentes, E Herrero, L Gala
INTRODUCTION: Microcytic carcinoma of the urinary bladder or bladder Small Cell Carcinoma (SCC) is a rare entity, characterised by an aggressive behaviour, with a poor prognosis, elevated metastatic potential, and is commonly found in older patients and in advanced disease stages. Here we present our experiences with the behaviour of the disease and the treatments applied. MATERIAL AND METHOD: This was a retrospective study on patients diagnosed with bladder SCC in our hospital between February 1992 and February 2014...
April 2016: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/26612361/hemoptysis-due-to-fungus-ball-after-tuberculosis-a-series-of-21-cases-treated-with-hemostatic-radiotherapy
#5
Lucas G Sapienza, Maria José L Gomes, Carmelindo Maliska, Antonio N Norberg
BACKGROUND: In patients who are not amenable to surgical resection (cavernostomy), it is difficult to achieve palliation of hemoptysis from pulmonary aspergilloma. There are only 9 cases with a short follow-up that have reported the use of radiotherapy for hemoptysis in this scenario. METHODS: A retrospective series of 21 patients with chronic necrotizing pulmonary aspergillosis were treated with radiotherapy (20 Gray) from 1990 to 2002. The outcome measures were the period from tuberculosis treatment to the onset of hemoptysis, hemoptysis resolution rate, change in Zubrod performance status after 30 days of the completion of radiotherapy, local failure-free survival, and overall survival...
November 26, 2015: BMC Infectious Diseases
https://www.readbyqxmd.com/read/26268084/zeolite-the-magic-stone-main-nutritional-environmental-experimental-and-clinical-fields-of-application
#6
Carmen Laurino, Beniamino Palmieri
INTRODUCTION: zeolites (clinoptilolites) are a family of alluminosilicates and cations clustered to form macro aggregates by small individual cavities. In the medical area they are involved in detoxification mechanisms capturing ions and molecules into their holes. Actually, we classify about 140 types of natural and 150 synthetic zeolites, for specific and selective use. Clinoptilolite is a natural zeolite and it is the most widespread compound in the medical market. OBJECTIVE: this review analyzes the main fields of zeolite utilization...
2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/26055212/oxidized-regenerated-cellulose-in-breast-surgery-experimental-model
#7
Gianluca Franceschini, Giuseppe Visconti, Alejandro Martin Sanchez, Alba Di Leone, Marzia Salgarello, Riccardo Masetti
BACKGROUND: Breast-conserving surgery (BCS) combined with postoperative radiotherapy has become the gold standard of locoregional treatment in patients with early-stage breast cancer. When large tumor resections are needed in small medium size breasts, oncoplastic procedures (OPP) have been introduced to improve the cosmetic result; but in several cases, OPP may be not sufficient to accomplish this purpose. Oxidized regenerated cellulose (ORC, Tabotamp fibrillar; Johnson & Johnson; Ethicon) has been reported to be useful in OPP to optimize the cosmetic results after OPP...
September 2015: Journal of Surgical Research
https://www.readbyqxmd.com/read/25982585/hypofractionated-radiation-therapy-for-treatment-of-bladder-carcinoma-in-patients-aged-90-years-and-more-a-new-paradigm-to-be-explored
#8
Benoîte Méry, Alexander T Falk, Avi Assouline, Jane-Chloé Trone, Jean-Baptiste Guy, Romain Rivoirard, Pierre Auberdiac, Julien Langrand Escure, Coralie Moncharmont, Guillaume Moriceau, Hweej Almokhles, Guy de Laroche, Cécile Pacaut, Aline Guillot, Cyrus Chargari, Nicolas Magné
INTRODUCTION: There are only scarce data on the optimal management of patients who present with a bladder carcinoma and who are aged 90 years and older. PATIENTS AND METHODS: We retrospectively reviewed records from radiotherapy departments from two university hospitals, two private centers and one public center to identify patients who underwent radiotherapy for bladder cancer over the past decade and who were aged 90 years or older. From 2003 to 2013, 14 patients aged 90 years or older receiving RT for bladder malignant tumors were identified...
July 2015: International Urology and Nephrology
https://www.readbyqxmd.com/read/24892345/a-respiratory-compensating-system-design-and-performance-evaluation
#9
Ho-Chiao Chuang, Ding-Yang Huang, Der-Chi Tien, Ren-Hong Wu, Chung-Hsien Hsu
This study proposes a respiratory compensating system which is mounted on the top of the treatment couch for reverse motion, opposite from the direction of the targets (diaphragm and hemostatic clip), in order to offset organ displacement generated by respiratory motion. Traditionally, in the treatment of cancer patients, doctors must increase the field size for radiation therapy of tumors because organs move with respiratory motion, which causes radiation-induced inflammation on the normal tissues (organ at risk (OAR)) while killing cancer cells, and thereby reducing the patient's quality of life...
May 8, 2014: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/24753779/cutaneous-metastasis-of-gastric-cardia-adenocarcinoma-in-a-patient-a-case-report
#10
Ying Wang, Guoqiang Kong, Xiaozhi Yuan, Shegan Gao
A large proportion of gastric cardia adenocarcinoma (GCA) present initially in an advanced stage in China. Skin metastasis of primary GCA rarely occurs and the incidence of it is still unclear yet. Here we report one case of skin metastasis from GCA in a 58-year-old male patient who underwent gastric cardia resection in 2002 and did not undergo chemotherapy. However, he was diagnosed with anastomotic stoma adenocarcinoma by gastroscopy and histological biopsy in 2012.4. Then he underwent four cycles of "XELOX" regimen chemotherapy and the evaluation was PR...
2014: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/24456773/the-efficacy-of-hemostatic-radiotherapy-for-bladder-cancer-related-hematuria-in-patients-unfit-for-surgery
#11
MULTICENTER STUDY
E Lacarrière, C Smaali, A Benyoucef, C Pfister, P Grise
OBJECTIVE: The aim of our study was to assess short and mid-term clinical efficacy of external beam radiation therapy to achieve hemostasis in patients with bladder-cancer related gross hematuria who were unfit for surgery. We also assessed hypofractionation as a possible alternative option for more severe patients. PATIENTS AND METHODS: Thirty-two patients were included for hemostatic radiation therapy, with two schedules based on Eastern Cooperative Oncology Group performance status...
November 2013: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/24353989/-treatment-induced-tumor-like-lesions-in-the-course-of-neurooncological-therapy
#12
REVIEW
György Attila Bagó, Eva Osztie, Péter Várallyay, Imre Fedorcsák
The proper interpretation of imaging changes in the course of multimodal neurooncological therapy (neurosurgery, radiotherapy, chemotherapy, stereotactic radiosurgery) is crucial. The appearance of abnormal or new contrast-enhancing lesions does not indicate obvious tumor progression, in the contrary they are frequently induced by the oncological therapy itself. The differentiation of real tumor progression from therapy-induced lesions is essential, since the diagnosis of progressive disease results in the termination of the current regimen and initiation of second or third line therapy, if possible...
December 2013: Magyar Onkologia
https://www.readbyqxmd.com/read/24101202/management-of-radiation-induced-rectal-bleeding
#13
REVIEW
Liboria Laterza, Paolo Cecinato, Alessandra Guido, Alessandro Mussetto, Lorenzo Fuccio
Pelvic radiation disease is one of the major complication after radiotherapy for pelvic cancers. The most commonly reported symptom is rectal bleeding which affects patients' quality of life. Therapeutic strategies for rectal bleeding are generally ignored and include medical, endoscopic, and hyperbaric oxygen treatments. Most cases of radiation-induced bleeding are mild and self-limiting, and treatment is normally not indicated. In cases of clinically significant bleeding (i.e. anaemia), medical therapies, including stool softeners, sucralfate enemas, and metronidazole, should be considered as first-line treatment options...
November 2013: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/23946599/treatment-of-hemorrhagic-radiation-induced-proctopathy-with-a-4-formalin-application-under-perianal-anesthetic-infiltration
#14
Narimantas Evaldas Samalavicius, Audrius Dulskas, Alfredas Kilius, Kestutis Petrulis, Darius Norkus, Arvydas Burneckis, Konstantinas Povilas Valuckas
AIM: To evaluate the results of hemorrhagic radiation proctopathy treatment with a 4% formalin application. METHODS: A prospective study was performed. Over a three-year period, 38 patients underwent 4% formalin application under perianal anesthetic infiltration for hemorrhagic radiation proctopathy. All patients included in the study were irradiated for prostate cancer. The patients ranged in age from 56-77 years (average 70 ± 5 years). All of the patients were referred for formalin therapy after noninvasive management had failed...
August 14, 2013: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/23919383/cancer-detection-and-management-in-patients-with-haemophilia-a-retrospective-european-multicentre-study
#15
C Biron-Andreani, P de Moerloose, R D'oiron, H Chambost, J-F Schved, C Hermans
Lymphomas or hepatocarcinomas related to blood-borne transmitted diseases are well-known malignancies in persons with haemophilia (PWH). However, rising life expectancy has increased the number of PWH suffering from other malignancies. This study aimed to collect cancer occurrence data in PWH followed in five European haemophilia treatment centres (Brussels, Geneva, Marseille, Montpellier and Paris-Bicêtre) over the last 10 years and to analyse some particular features of cancer occurring in PWH. In total, 45 malignancies were diagnosed in 1067 PWH...
January 2014: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/23846664/management-of-intractable-epistaxis-in-patients-who-received-radiation-therapy-for-nasopharyngeal-carcinoma
#16
Cheng-Cheng He, Yong-Feng Si, Yu-An Xie, Lei Yu
To report clinical manifestations, bleeding point localization, and outcomes of management in 16 patients with 16 instances of intractable epistaxis after radiation therapy for nasopharyngeal carcinoma. Retrospective chart review of 16 patients with nasopharyngeal carcinoma (mean age 52.06 ± 14.37 years) with 16 instances of intractable epistaxis during the past 5 years, whose diagnosis was confirmed by angiography (n = 10) or MRI/CT imaging studies and clinical manifestations (n = 6). The mean radiation dose to the affected carotid artery was 101...
September 2013: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/23736909/a-cure-for-post-radiation-proctitis
#17
Cesare Perotti, Claudia Del Fante, Costanza Alvisi, Marila Cervio, Luigia Scudeller
No abstract text is available yet for this article.
January 2014: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/23585523/regional-lymph-node-metastases-are-a-strong-risk-factor-for-venous-thromboembolism-results-from-the-vienna-cancer-and-thrombosis-study
#18
Boris Dickmann, Jonas Ahlbrecht, Cihan Ay, Daniela Dunkler, Johannes Thaler, Werner Scheithauer, Peter Quehenberger, Christoph Zielinski, Ingrid Pabinger
Advanced cancer is a risk factor for venous thromboembolism. However, lymph node metastases are usually not considered an established risk factor. In the framework of the prospective, observational Vienna Cancer and Thrombosis Study we investigated the association between local (N0), regional (N1-3), and distant (M1) cancer stages and the occurrence of venous thromboembolism. Furthermore, we were specifically interested in the relationship between stage and biomarkers that have been reported to be associated with venous thromboembolism...
August 2013: Haematologica
https://www.readbyqxmd.com/read/22911081/a-novel-approach-to-closure-of-perineal-wounds-during-abdominoperineal-resection-use-of-fibrin-sealant
#19
Sachin Vaid, Thomas Nicholson
Abdominoperineal resection is associated with significant morbidity. The perineal wound poses a unique risk and complications are common, including skin breakdown, abscess, sinus tracts, perineal herniation, and evisceration. A 2-component fibrin sealant made from pooled human plasma has been proven to achieve hemostasis and tissue sealing. We report a case series of 5 consecutive patients in whom we used this fibrin sealant during perineal wound closure. Of our patients, 2 patients (40%) were diabetic and 4 patients (80%) received preoperative radiotherapy...
August 2012: Archives of Surgery
https://www.readbyqxmd.com/read/22863072/clinically-significant-bleeding-in-incurable-cancer-patients-effectiveness-of-hemostatic-radiotherapy
#20
Nikola Cihoric, Susanne Crowe, Steffen Eychmüller, Daniel M Aebersold, Pirus Ghadjar
BACKGROUND: This study was performed to evaluate the outcome after hemostatic radiotherapy (RT) of significant bleeding in incurable cancer patients. METHODS: Patients treated by hemostatic RT between November 2006 and February 2010 were retrospectively analyzed. Bleeding was assessed according to the World Health Organization (WHO) scale (grade 0 = no bleeding, 1 = petechial bleeding, 2 = clinically significant bleeding, 3 = bleeding requiring transfusion, 4 = bleeding associated with fatality)...
2012: Radiation Oncology
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