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https://www.readbyqxmd.com/read/28620574/complications-of-advanced-kadish-stage-esthesioneuroblastoma-single-institution-experience-and-literature-review
#1
Sheri K Palejwala, Saurabh Sharma, Christopher H Le, Eugene Chang, Michael Lemole
INTRODUCTION: In esthesioneuroblastoma, greater disease extent and Kadish staging correlate with greater recurrence, complications, and mortality. These advanced stage malignancies require extensive resections and aggressive adjuvant therapy. This increases the risk of complications such as cerebrospinal fluid leak, neurologic deficits, and osteomyelitis. We present our case series and then analyze the literature to ascertain whether advanced stage tumors corresponds to greater rates of complications...
May 12, 2017: Curēus
https://www.readbyqxmd.com/read/28619579/recording-sympathetic-nerve-activity-from-the-skin
#2
REVIEW
Thomas H Everett, Anisiia Doytchinova, Yong-Mei Cha, Peng-Sheng Chen
Sympathetic tone is important in cardiac arrhythmogenesis; however, methods to estimate sympathetic tone are either invasive or require proper sinus node function that may be abnormal in disease states. Because of the direct and extensive connections among various nerve structures, it is possible for the sympathetic nerves in the various structures to activate simultaneously. Therefore, we hypothesized that nerve activity can be recorded from the skin and it can be used to estimate the cardiac sympathetic tone...
May 10, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28614386/a-systemic-macrophage-response-is-required-to-contain-a-peripheral-poxvirus-infection
#3
Michael L Davies, Nikhil J Parekh, Lauren W Kaminsky, Chetna Soni, Irene E Reider, Tracy E Krouse, Matthew A Fischer, Nico van Rooijen, Ziaur S M Rahman, Christopher C Norbury
The goal of the innate immune system is to reduce pathogen spread prior to the initiation of an effective adaptive immune response. Following an infection at a peripheral site, virus typically drains through the lymph to the lymph node prior to entering the blood stream and being systemically disseminated. Therefore, there are three distinct spatial checkpoints at which intervention to prevent systemic spread of virus can occur, namely: 1) the site of infection, 2) the draining lymph node via filtration of lymph or 3) the systemic level via organs that filter the blood...
June 14, 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28613434/cardiac-heterogeneity-and-drug-provoked-arrhythmias
#4
EDITORIAL
Ursula Ravens, Christian Aalkjaer
Functioning of the heart as a mechanical pump depends on electrical impulse formation in the sinus node, conduction of the excitatory wave along its preformed pathways, and orderly repolarisation. This article is protected by copyright. All rights reserved.
June 14, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/28593151/the-absence-of-atrial-contraction-as-a-predictor-of-permanent-pacemaker-implantation-after-maze-procedure-with-cryoablation
#5
Chang-Seok Jeon, Man-Shik Shim, Seung-Jung Park, Dong Seop Jeong, Kyoung-Min Park, Young Keun On, June Soo Kim, Pyo Won Park
BACKGROUND: The absence of atrial contraction (AC) after the maze procedure has been reported to cause subsequent annular dilatation and to increase the risk of embolic stroke. We hypothesized that the lack of AC could increase the risk of permanent pacemaker (PPM) implantation in patients undergoing the maze procedure. METHODS: In 376 consecutive patients who had undergone a cryo-maze procedure and combined valve operation, recovery of AC was assessed at baseline and at immediate (≤2 weeks), early (≤1 year, 4...
June 2017: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28584281/mass-spectrometry-imaging-identifies-palmitoylcarnitine-as-an-immunological-mediator-during-salmonella-typhimurium-infection
#6
Heather E Hulme, Lynsey M Meikle, Hannah Wessel, Nicole Strittmatter, John Swales, Carolyn Thomson, Anna Nilsson, Robert J B Nibbs, Simon Milling, Per E Andren, C Logan Mackay, Alex Dexter, Josephine Bunch, Richard J A Goodwin, Richard Burchmore, Daniel M Wall
Salmonella Typhimurium causes a self-limiting gastroenteritis that may lead to systemic disease. Bacteria invade the small intestine, crossing the intestinal epithelium from where they are transported to the mesenteric lymph nodes (MLNs) within migrating immune cells. MLNs are an important site at which the innate and adaptive immune responses converge but their architecture and function is severely disrupted during S. Typhimurium infection. To further understand host-pathogen interactions at this site, we used mass spectrometry imaging (MSI) to analyse MLN tissue from a murine model of S...
June 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28580699/prognostic-value-of-lymphovascular-invasion-of-the-primary-tumor-in-hypopharyngeal-carcinoma-after-total-laryngopharyngectomy
#7
Yuki Saito, Go Omura, Kazuo Yasuhara, Ryoko Rikitake, Ken Akashi, Osamu Fukuoka, Masafumi Yoshida, Mizuo Ando, Takahiro Asakage, Tatsuya Yamasoba
BACKGROUND: We aimed to determinate the prognostic value of lymphovascular invasion in the specimens resected during total laryngopharyngectomy for hypopharyngeal carcinoma. METHODS: Patients who underwent total laryngopharyngectomy at our institution between 2004 and 2014 were included in this study and retrospectively analyzed. We then discriminated for vascular invasion and lymphatic invasion of the primary tumor in all cases. RESULTS: We reviewed 135 records (120 men and 15 women; age range, 36-84 years)...
June 5, 2017: Head & Neck
https://www.readbyqxmd.com/read/28577544/deactivation-vs-asynchronous-pacing-prospective-evaluation-of-a-protocol-for-rhythm-management-in-patients-with-magnetic-resonance-conditional-pacemakers-undergoing-adenosine-stress-cardiovascular-magnetic-resonance-imaging
#8
Oliver Klein-Wiele, Marietta Garmer, Gianluca Barbone, Rhyan Urbien, Martin Busch, Kaffer Kara, Harald Schäfer, Michael Schulte-Hermes, Birgit Hailer, Dietrich Grönemeyer
BACKGROUND: Cardiovascular Magnetic Resonance (CMR) imaging with adenosine stress is an important diagnostic tool in patients with known or suspected coronary artery disease (CAD). However, the method is not yet established for CAD patients with pacemakers (PM) in clinical practice. A possible reason is that no recommendations exist for PM setting (paused pacing or asynchronous mode) during adenosine stress. We elaborated a protocol for rhythm management in clinical routine for PM patients that considers heart rate changes under adenosine using a test infusion of adenosine in selected patients...
June 2, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28562571/hemodynamic-instability-after-pulmonary-veins-isolation-in-a-patient-with-dual-chamber-pacemaker-the-phantom-injury-of-the-ventricular-lead
#9
Márcio Galindo Kiuchi, Guilherme Miglioli Lobato, Shaojie Chen
INTRODUCTION: The standard treatment of sinus node dysfunction (SND) is the pacemaker implantation, and the ideal methodology for the management of atrial fibrillation (AF) is rhythm control, but this is sometimes very hard to accomplish. For such actions, complete isolation of all pulmonary veins (PVI) is currently widely accepted as the best endpoint. CASE PRESENTATION: In this case, we report a female patient, 81 years old, with controlled hypertension, without coronary artery disease, bearer of bilateral knee replacement, and dual chamber pacemaker implanted 1...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28543956/influence-of-frailty-on-the-quality-of-life-patients-qualified-for-pacemaker-implantation
#10
Agnieszka Mlynarska, Rafal Mlynarski, Krzysztof S Golba
AIMS AND OBJECTIVES: An important question is whether frailty syndrome affects the assessment of quality of life or whether frailty syndrome may reduce the benefits of a cardiac pacemaker implantation. BACKGROUND: Frailty syndrome is known risk factor for quality of life evaluation after selected cardiology invasive procedures. DESIGN: The study was designed as single center prospective study. METHODS: The study included 171 patients aged ≥ 60 years who were qualified for pacemaker implantation...
May 25, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28541006/focal-atrial-tachycardia-arising-from-the-inferior-vena-cava
#11
Yeong Min Lim, Jae Sun Uhm, Hui Nam Pak
The inferior vena cava (IVC) is a rare site of focal atrial tachycardia (AT). Here, we report a 20-year-old woman who underwent catheter ablation for anti-arrhythmic drug-resistant AT originating from the IVC. She had undergone open-heart surgery for patch closure of an atrial septal defect 17 years previously and permanent pacemaker implantation for sinus node dysfunction 6 years previously. The AT focus was at the anterolateral aspect of the IVC-right atrial junction, and it was successfully ablated under three-dimensional electroanatomical-mapping guidance...
July 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28529049/heterogeneity-of-transverse-axial-tubule-system-in-mouse-atria-remodeling-in-atrial-specific-na-ca-2-exchanger-knockout-mice
#12
Xin Yue, Rui Zhang, Brian Kim, Aiqun Ma, Kenneth D Philipson, Joshua I Goldhaber
Transverse-axial tubules (TATs) are commonly assumed to be sparse or absent in atrial myocytes from small animals. Atrial myocytes from rats, cats and rabbits lack TATs, which results in a characteristic "V"-shaped Ca release pattern in confocal line-scan recordings due to the delayed rise of Ca in the center of the cell. To examine TAT expression in isolated mouse atrial myocytes, we loaded them with the membrane dye Di-4-ANEPPS to label TATs. We found that >80% of atrial myocytes had identifiable TATs...
May 19, 2017: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/28516212/anatomical-visualization-of-neural-course-and-distribution-of-anterior-ascending-aortic-plexus
#13
Tomokazu Kawashima, Fumi Sato
The aim of this study was to document the detailed anatomy of neural course and distribution on the anterior ascending aorta, to identify the high and low density areas of the anterior ascending aortic plexus for further understandings in cardiovascular surgery. The embalmed hearts of 42 elderly individuals were submacroscopically and microscopically examined, after excluding any that were macroscopically abnormal. With its origins in the anterior ascending aortic plexus, the right coronary plexus substantially innervated the right coronary artery, the right atrium and ventricle, and the sinus node...
May 17, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28509140/a-rare-adult-case-of-poststreptococcal-acute-glomerulonephritis-with-a-retropharyngeal-abscess
#14
Tsuyoshi Takashima, Sae Hirata, Mai Nonaka, Keiichiro Matsumoto, Yuki Awanami, Masatora Yamasaki, Makoto Fukuda, Motoaki Miyazono, Yuji Ikeda
Retropharyngeal abscess is an infection involving the retropharyngeal space which is posterior to the pharynx and oesophagus, and it results as a complication of a primary infection elsewhere in the head and neck including the nasopharynx, paranasal sinuses, or middle ear, which drain lymph to the retropharyngeal lymph nodes. Their lymph nodes are prominent in children and atrophy with age. Therefore, retropharyngeal abscess is most frequently encountered in children, with 75% of cases occurring before the age of 5 years, and often in the first year of life...
May 2017: CEN Case Reports
https://www.readbyqxmd.com/read/28507743/electrophysiological-testing-for-the-investigation-of-bradycardias
#15
Demosthenes G Katritsis, Mark E Josephson
In this article we review the role of electrophysiological testing in patients presenting with bradycardia due to sinus node or atrioventricular node disease. In sinus bradycardia the role of electrophysiology studies is not established. In AV conduction disturbances, an electrophysiology study may be necessary both for the establishment of atrioventricular block as the main cause of symptoms, and for identification of the anatomic site of block that may dictate the potential need of permanent pacing.
April 2017: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/28507237/multiscale-ordinal-network-analysis-of-human-cardiac-dynamics
#16
M McCullough, M Small, H H C Iu, T Stemler
In this study, we propose a new information theoretic measure to quantify the complexity of biological systems based on time-series data. We demonstrate the potential of our method using two distinct applications to human cardiac dynamics. Firstly, we show that the method clearly discriminates between segments of electrocardiogram records characterized by normal sinus rhythm, ventricular tachycardia and ventricular fibrillation. Secondly, we investigate the multiscale complexity of cardiac dynamics with respect to age in healthy individuals using interbeat interval time series and compare our findings with a previous study which established a link between age and fractal-like long-range correlations...
June 28, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28503389/rosai-dorfman-disease-of-the-breast
#17
Eileen E Delaney, Anne Larkin, Sue MacMaster, Ali Sakhdari, Carolynn M DeBenedectis
Rosai-Dorfman disease (also known as sinus histiocytosis with massive lymphadenopathy) is a rare benign proliferative disorder of histiocytes that typically involves the lymph nodes and can also involve extranodal sites. Rosai-Dorfman disease confined to the breast is extremely rare, but important to recognize as it can mimic malignancy. We present the case of a 63-year-old woman who presented with a palpable breast lump that was highly suspicious for malignancy based on mammogram and ultrasound appearance...
April 11, 2017: Curēus
https://www.readbyqxmd.com/read/28495981/pacing-discovery-g-protein-%C3%AE-subunit-mutations-in-sinus-node-dysfunction
#18
EDITORIAL
Elisabeth M Lodder, Arie O Verkerk, Connie R Bezzina
No abstract text is available yet for this article.
May 12, 2017: Circulation Research
https://www.readbyqxmd.com/read/28495249/heart-rate-variability-to-monitor-performance-in-elite-athletes-criticalities-and-avoidable-pitfalls
#19
Daniela Lucini, Ilaria Marchetti, Antonio Spataro, Mara Malacarne, Manuela Benzi, Stefano Tamorri, Roberto Sala, Massimo Pagani
BACKGROUND: Spectral analysis of Heart Rate Variability (HRV) is a simple, non-invasive technique that is widely used in sport to assess sympatho-vagal regulation of the heart. Its employment is increasing partly due to the rising usage of wearable devices. However data acquisition using these devices may be suboptimal because they cannot discriminate between sinus and non-sinus beats and do not record any data regarding respiratory frequency. This information is mandatory for a correct clinical interpretation...
May 3, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28491745/transvenous-approach-to-pacemaker-lead-implantation-for-sinus-node-dysfunction-after-extracardiac-lateral-tunnel-fontan-conduit-placement
#20
Edward O'Leary, Mark E Alexander, Francis Fynn-Thompson, Douglas Mah
No abstract text is available yet for this article.
November 2016: HeartRhythm Case Reports
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