keyword
MENU ▼
Read by QxMD icon Read
search

New research

keyword
https://www.readbyqxmd.com/read/29169187/biologically-active-orbitides-from-the-euphorbiaceae-family
#1
Suelem D Ramalho, Meri Emili F Pinto, Douglas Ferreira, Vanderlan S Bolzani
A comprehensive overview of natural orbitides isolated from Euphorbiaceae species and their most relevant biological activities are presented. Euphorbiaceae is a large and diverse family, which comprises about 300 genera, and is known as an important source of medicines and toxins. Several classes of secondary metabolites have been described for this taxon, however, orbitides have been broadly reported in Jatropha and Croton genera. Additionally, the latex is documented as the main source of orbitides in this family...
November 23, 2017: Planta Medica
https://www.readbyqxmd.com/read/29169140/facile-green-synthesis-of-zinc-oxide-nanoparticles-using-ulva-lactuca-seaweed-extract-and-evaluation-of-their-photocatalytic-antibiofilm-and-insecticidal-activity
#2
Ramachandran Ishwarya, Baskaralingam Vaseeharan, Subramanian Kalyani, Balan Banumathi, Marimuthu Govindarajan, Naiyf S Alharbi, Shine Kadaikunnan, Mohammed N Al-Anbr, Jamal M Khaled, Giovanni Benelli
The bioactivity of semiconductor nanocomplexes has been poorly studied in the field of pesticide science. In this research, the synthesis of zinc nanoparticles was accomplished through new effortless green chemistry process, using the Ulva lactuca seaweed extract as a reducing and capping agent. The production of U. lactuca-fabricated ZnO nanoparticles (Ul-ZnO Nps) was characterized by powder X-ray diffraction (XRD), UV-visible, Fourier transform infrared (FTIR) spectroscopy, selected area electron diffraction (SAED) analysis and transmission electron microscopy (TEM)...
November 7, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29169111/identification-of-phenolic-components-via-lc-ms-analysis-and-biological-activities-of-two-centaurea-species-c-drabifolia-subsp-drabifolia-and-c-lycopifolia
#3
Gokhan Zengin, Dimitrina Zheleva-Dimitrova, Reneta Gevrenova, Paraskev Nedialkov, Andrei Mocan, Ana Ćirić, Jasmina Glamočlija, Marina Soković, Abdurrahman Aktumsek, M Fawzi Mahomoodally
The Centaurea genus has great potential in traditional systems and has attracted much interest in the design of novel drug formulations. The present study was focused on the chemical fingerprints and biological properties of Centaurea drabifolia subsp. drabifolia and Centaurea lycopifolia extracts. Spectrophotometric and LC-MS techniques were used to establish the chemical profiles of the studied extracts. Enzyme inhibitory potential was assessed against key enzymes linked to global health problems, namely neurodegenerative diseases (acetylcholinesterase), pigmentation (tyrosinase), and diabetes (α-amylase and α-glucosidase)...
November 20, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29169062/study-on-a-new-design-of-tehran-research-reactor-for-radionuclide-production-based-on-fast-neutrons-using-mcnpx-code
#4
Nadia Zandi, Hossein Afarideh, Mohammad Reza Aboudzadeh, Saeed Rajabifar
The aim of this work is to increase the magnitude of the fast neutron flux inside the flux trap where radionuclides are produced. For this purpose, three new designs of the flux trap are proposed and the obtained fast and thermal neutron fluxes compared with each other. The first and second proposed designs were a sealed cube contained air and D2O, respectively. The results of calculated production yield all indicated the superiority of the latter by a factor of 55% in comparison to the first proposed design...
November 6, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/29169057/synthetic-social-support-theorizing-lay-health-worker-interventions
#5
Nicola K Gale, Sara Kenyon, Christine MacArthur, Kate Jolly, Lucy Hope
Levels of social support are strongly associated with health outcomes and inequalities. The use of lay health workers (LHWs) has been suggested by policy makers across the world as an intervention to identify risks to health and to promote health, particularly in disadvantaged communities. However, there have been few attempts to theorize the work undertaken by LHWs to understand how interventions work. In this article, the authors present the concept of 'synthetic socialsupport' and distinguish it from the work of health professionals or the spontaneous social support received from friends and family...
November 8, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29168985/association-between-diet-quality-and-measures-of-body-adiposity-using-the-rate-your-plate-survey-in-patients-presenting-for-coronary-angiography
#6
Lisa Ganguzza, Calvin Ngai, Laura Flink, Kathleen Woolf, Yu Guo, Eugenia Gianos, Joseph Burdowski, James Slater, Victor Acosta, Tamsin Shephard, Binita Shah
BACKGROUND: Diet is a modifiable risk factor for cardiovascular disease; however, dietary patterns are historically difficult to capture in the clinical setting. Healthcare providers need assessment tools that can quickly summarize dietary patterns. Research should evaluate the effectiveness of these tools, such as Rate Your Plate (RYP), in the clinical setting. HYPOTHESIS: RYP diet quality scores are associated with measures of body adiposity in patients referred for coronary angiography...
November 23, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/29168945/analysis-of-the-experiences-of-nurses-who-return-to-nursing-after-cancer
#7
Karen-Leigh Edward, Jo-Ann Giandinoto, Judelle McFarland
BACKGROUND: understanding the impact of role ambiguity (both professional and patient) can be a factor in deepening the understanding of the ongoing personal, professional and organisational requirements of nurses who are cancer survivors. PURPOSE: the aim of this qualitative study was to elucidate an in-depth description of nurses' experiences of surviving cancer. METHOD: an exploratory qualitative research design was used (n=8), with participants recruited between September 2014 and December 2016...
November 23, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/29168903/black-phosphorus-based-orientation-induced-diodes
#8
Wei Xin, Xiao-Kuan Li, Xin-Ling He, Bao-Wang Su, Xiao-Qiang Jiang, Kai-Xuan Huang, Xiang-Feng Zhou, Zhi-Bo Liu, Jian-Guo Tian
Despite many decades of research of diodes, which are fundamental components of electronic and photoelectronic devices with p-n or Schottky junctions using bulk or 2D materials, stereotyped architectures and complex technological processing (doping and multiple material operations) have limited future development. Here, a novel rectification device, an orientation-induced diode, assembled using only few-layered black phosphorus (BP) is investigated. The key to its realization is to utilize the remarkable anisotropy of BP in low dimensions and change the charge-transport conditions abruptly along the different crystal orientations...
November 23, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29168875/appreciation-of-symmetry-in-natural-product-synthesis
#9
REVIEW
Wen-Ju Bai, Xiqing Wang
Covering: 2012 to June 2017This review aims to show that complex natural product synthesis can be streamlined by taking advantage of molecular symmetry. Various strategies to construct molecules with either evident or hidden symmetry are illustrated. Insights regarding the origins and adjustments of these strategies as well as inspiring new methodological developments are deliberated. When a symmetric strategy fails, the corresponding reason is analysed and an alternative approach is briefly provided. Finally, the importance of exploiting molecular symmetry and future research directions are discussed...
November 23, 2017: Natural Product Reports
https://www.readbyqxmd.com/read/29168868/structural-elucidation-and-immunostimulatory-activity-of-a-new-polysaccharide-from-cordyceps-militaris
#10
Sixue Bi, Yongshuai Jing, Qinqin Zhou, Xianjing Hu, Jianhua Zhu, Zhongyi Guo, Liyan Song, Rongmin Yu
A new polysaccharide (CMPB90-1) was isolated from cultured Cordyceps militaris by alkaline extraction. The chemical structure of CMPB90-1 was determined by analysis of physicochemical and spectral data. The backbone of CMPB90-1 is composed of (1→6)-linked α-d-glucopyranosyl and (1→3)-linked α-d-glucopyranosyl residues, with branching at O-6, which consists of (1→4)-linked β-d-mannopyranosyl and (1→6)-linked α-d-glucopyranosyl residues, respectively. β-d-Galactopyranosyl residues is the terminal unit...
November 23, 2017: Food & Function
https://www.readbyqxmd.com/read/29168697/direct-contact-membrane-distillation-for-textile-wastewater-treatment-a-state-of-the-art-review
#11
Heloisa Ramlow, Ricardo Antonio Francisco Machado, Cintia Marangoni
To meet surging water demands, water reuse is being sought as an alternative to traditional water resources. Direct contact membrane distillation (DCMD) has been increasingly studied in the past decade for its potential as an emerging cost effective wastewater treatment process and subsequent water reuse. This review presents a comprehensive overview of the current progress in the application of DCMD for textile wastewater treatment based on the available state of the art. There are already published review papers about the membrane distillation process, but the difference in the present work is that it focuses on the textile area, which consumes a lot of water and generates large amounts of wastewater, and still needs innovations in the sector...
November 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29168677/social-media-channels-in-health-care-research-and-rising-ethical-issues
#12
Samy A Azer
Social media channels such as Twitter, Facebook, and LinkedIn have been used as tools in health care research, opening new horizons for research on health-related topics (e.g., the use of mobile social networking in weight loss programs). While there have been efforts to develop ethical guidelines for internet-related research, researchers still face unresolved ethical challenges. This article investigates some of the risks inherent in social media research and discusses how researchers should handle challenges related to confidentiality, privacy, and consent when social media tools are used in health-related research...
November 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/29168430/triple-negative-breast-cancer-prognostic-role-of-immune-related-factors-a-systematic-review
#13
Elisabeth Specht Stovgaard, Dorte Nielsen, Estrid Hogdall, Eva Balslev
PURPOSE: Treatment of breast cancer has been increasingly successful in recent years with the advent of HER2-receptor targeted treatment and endocrine treatment. However, the triple negative subgroup of breast cancer (TNBC) (estrogen-, progesterone- and HER2-receptor negative) still lacks targeted treatment options. TNBC is a type of breast cancer that often affects younger women, and generally has a worse prognosis than other types of breast cancer. Recently, the complex role of the immune system in cancer growth, elimination and metastasis has been the object of increased attention...
November 23, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/29168291/the-col5a3-and-mmp9-genes-interact-in-eczema-susceptibility
#14
Patricia Margaritte-Jeannin, Marie-Claude Babron, Catherine Laprise, Nolwenn Lavielle, Chloé Sarnowski, Myriam Brossard, Miriam Moffatt, Valérie Gagné-Ouellet, Adrien Etcheto, Mark Lathrop, Jocelyne Just, William O Cookson, Emmanuelle Bouzigon, Florence Demenais, Marie-Hélène Dizier
BACKGROUND: Genetic studies of eczema have identified many genes, which explain only 14% of the heritability. Missing heritability may be partly due to ignored Gene-Gene (G-G) interactions. OBJECTIVE: Our aim was to detect new interacting genes involved in eczema. METHODS: The search for G-G interaction in eczema was conducted using a two-step approach, which included as a first step, a biological selection of genes, which are involved either in the skin or epidermis development or in the collagen metabolism, and as a second-step, an interaction analysis of the selected genes...
November 23, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29168245/homology-based-hydrogen-bond-information-improves-crystallographic-structures-in-the-pdb
#15
Bart van Beusekom, Wouter G Touw, Mahidhar Tatineni, Sandeep Somani, Gunaretnam Rajagopal, Jinquan Luo, Gary L Gilliland, Anastassis Perrakis, Robbie P Joosten
The Protein Data Bank (PDB) is the global archive for structural information on macromolecules, and a popular resource for researchers, teachers and students, amassing more than one million unique users each year. Crystallographic structure models in the PDB (more than 100,000 entries) are optimized against the crystal diffraction data and geometrical restraints. This process of crystallographic refinement typically ignored hydrogen bond (H-bond) distances as a source of information. However, H-bond restraints can improve structures at low resolution where diffraction data are limited...
November 23, 2017: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/29168195/for-whom-we-forgive-matters-relationship-focus-magnifies-but-self-focus-buffers-against-the-negative-effects-of-forgiving-an-exploitative-partner
#16
Jordan Brian Gabriels, Peter Strelan
Increasingly, studies indicate that victims experience negative outcomes after forgiving offenders who present an exploitation risk. However, we demonstrate that the link between exploitation risk and forgiveness-related outcomes is dependent upon a victim's focus of forgiving. Two studies, the first employing a prospective design (N = 110) and the second an experimental scenario method (N = 261), replicate previous research on the negative effects of exploitation risk and also test two new hypotheses. First, we found that forgiving explicitly for the sake of a relationship is associated with greater distress, relative to deciding to forgive for the sake of the self...
November 22, 2017: British Journal of Social Psychology
https://www.readbyqxmd.com/read/29168081/high-glucose-stimulates-expression-of-mfhas1-to-mitigate-inflammation-via-akt-ho-1-pathway-in-human-umbilical-vein-endothelial-cells
#17
Hui-Hui Wang, Peng-Fei Sun, Wan-Kun Chen, Jing Zhong, Qi-Qing Shi, Mei-Lin Weng, Duan Ma, Chang-Hong Miao
Hyperglycemia is a highly dangerous factor to various diseases, even resulting in death of people. Inflammation plays a key role in this process. The aim of this study was to explore the role of malignant fibrous histiocytoma amplified sequence 1 (MFHAS1) in high-glucose induced inflammation. Our research showed that high glucose stimulated the expression of MFHAS1, and overexpression of MFHAS1 can attenuate high-glucose induced inflammation in endothelial cells by decreasing the secretion of cytokines interleukin-1β (IL-1β), interleukin-1α (IL-1α), adhesion molecule intercellular adhesion molecule-1 (ICAM), interleukin-6 (IL-6), interleukin-8 (IL-8), and chemokine ligand 1 (CXCL-1)...
November 22, 2017: Inflammation
https://www.readbyqxmd.com/read/29168045/biocompatibility-of-intravitreal-injection-of-human-mesenchymal-stem-cells-in-immunocompetent-rabbits
#18
Sonia Labrador Velandia, Salvatore Di Lauro, Maria Luz Alonso-Alonso, Soraya Tabera Bartolomé, Girish Kumar Srivastava, José Carlos Pastor, Ivan Fernandez-Bueno
PURPOSE: To evaluate the feasibility, safety, and biocompatibility of intravitreal injection of human mesenchymal stem cells (MSCs) in immunocompetent pigmented rabbits. MATERIALS AND METHODS: Thirty-two pigmented rabbits (24 females, 8 males; Chinchilla-New Zealand White) were divided into 8 groups of 4 animals. Commercially prepared human MSCs were injected (0.05 ml) into the post-lens vitreous of the right eyes. Groups 1 and 4 received isotonic medium (Ringer lactate-based), groups 2, 5, 7, and 8 received a low dose of 15 × 10(6) cells/ml...
November 22, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29167984/x-ray-micro-computed-tomography-in-pediatric-surgery-a-new-tool-for-studying-embryos
#19
Susann Brosig, N Peukert, R Metzger, H Schneider, R Haak, J Gosemann, M Lacher, D Kluth
PURPOSE: The embryology of common congenital malformations is discussed controversially. Studies are hampered by a shortage of study material and techniques which require partial or complete preparation and therewith destruction of embryos. X-ray micro-computed-tomography (µCT) is a technical opportunity keeping the embryos intact. Thus, the aim of this study was to assess the applicability of µCT in embryonic research compared to the anatomical information obtained by scanning electron microscopy (SEM)...
November 22, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29167982/successional-changes-in-trophic-interactions-support-a-mechanistic-model-of-post-fire-population-dynamics
#20
Annabel L Smith
Models based on functional traits have limited power in predicting how animal populations respond to disturbance because they do not capture the range of demographic and biological factors that drive population dynamics, including variation in trophic interactions. I tested the hypothesis that successional changes in vegetation structure, which affected invertebrate abundance, would influence growth rates and body condition in the early-successional, insectivorous gecko Nephrurus stellatus. I captured geckos at 17 woodland sites spanning a succession gradient from 2 to 48 years post-fire...
November 22, 2017: Oecologia
keyword
keyword
97012
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"