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https://www.readbyqxmd.com/read/28545504/a-case-report-of-zinc-phosphide-poisoning-complicated-by-acute-renal-failure-and-tubulo-interstitial-nephritis
#1
Nilukshana Yogendranathan, H M M T B Herath, Thenuka Sivasundaram, R Constantine, Aruna Kulatunga
BACKGROUND: Run Rat® is a rodenticide widely used against small mammals. It comprises of a minimum of 32% zinc phosphide which is highly toxic in acute exposures to humans. It may be consumed accidentally or intentionally. It enters the body via skin, respiratory and gastrointestinal tracts. Zinc phosphide is hydrolyzed by the gastric acid and is transformed into phosphine gas. Phosphine is a respiratory toxin that inhibits cytochrome C oxidase system resulting in renal failure and liver failure...
May 25, 2017: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28544949/the-influence-of-shoe-aging-on-children-running-biomechanics
#2
Alexis Herbaut, Pascale Chavet, Maxime Roux, Nils Guéguen, Franck Barbier, Emilie Simoneau-Buessinger
Athletic children are prone to overuse injuries, especially at the heel and knee. Since footwear is an extrinsic factor of lower limb injury risk, the aim of this study was to assess the influence of shoe aging on children running biomechanics. Fourteen children active in sports participated in a laboratory biomechanical evaluation. A new pair of shoes was provided to each participant at an inclusion visit. Four months later, the participants performed a running task and their kinematics and kinetics were assessed both with their used shoes and with a new pair of shoes identical to the first...
May 17, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28543791/the-association-between-eccentric-hip-abduction-strength-and-hip-and-knee-angular-movements-in-recreational-male-runners-an-explorative-study
#3
René B K Brund, Sten Rasmussen, Rasmus O Nielsen, Uwe G Kersting, Uffe Laessoe, Michael Voigt
Weak hip abductors may be related with increased hip adduction and knee abduction angular movement, which may be risk factors of lower extremity injuries. Since the role of eccentric hip abduction strength (EHAS) on hip adduction angular movement and the knee abduction angular movement (KABD) remains unclear and the purpose of the present study was to explore the association between EHAS and hip- and knee angular movement. In 100 healthy male recreational runners, EHAS was quantified using an isokinetic dynamometer, while hip- and knee angular movement were collected using pressure sensitive treadmill and Codamotion active marker system...
May 24, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28538328/a-systematic-review-of-the-association-between-physical-fitness-and-musculoskeletal-injury-risk-part-1-cardiorespiratory-endurance
#4
Peter J Lisman, Sarah J de la Motte, Timothy C Gribbin, Dianna P Jaffin, Kaitlin Murphy, Patricia A Deuster
Lisman, PJ, de la Motte, SJ, Gribbin, TC, Jaffin, DP, Murphy, K, and Deuster, PA. A systematic review of the association between physical fitness and musculoskeletal injury risk: part 1-cardiorespiratory endurance. J Strength Cond Res 31(6): 1744-1757, 2017-Musculoskeletal injuries (MSK-Is) are a significant health problem for both military and athletic populations. Research indicates that MSK-I is associated with physical fitness; however, the association between specific components of physical fitness and MSK-I in military and athletic populations has not been systematically examined...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28532908/the-safety-and-efficiency-of-pvcr-without-anterior-support-applied-in-treatment-of-yang-s-a-type-severe-thoracic-kyphoscoliosis
#5
Wen-Yuan Sui, Zi-Fang Huang, Yao-Long Deng, Heng-Wei Fan, Jing-Fan Yang, Fo-Bao Li, Jun-Lin Yang
OBJECT: To assess the clinical and radiographic outcomes of posterior vertebral column resection (PVCR) without anterior support in treatment of Yang's A type severe rigid thoracic kyphoscoliosis. METHODS: The records of 27 Yang's A type severe thoracic kyphoscoliosis patients treated with PVCR without anterior support from January 2010 to September 2013 were retrospectively analyzed. Intraoperative multimodal neurophysiological monitoring (IONM) (6 modes: Somatosensory evoked potential (SSEP), Motor evoked potential (MEP), Descending neurogenic evoked potential (DNEP), Spinal cord evoked potential (SCEP), and Electromyography, both triggered and free run EMG) was conducted in all patients...
May 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28525884/training-volume-and-soft-tissue-injury-in-professional-and-non-professional-rugby-union-players-a-systematic-review
#6
Shane Ball, Mark Halaki, Rhonda Orr
AIM: To investigate the relationship between training volume and soft tissue injury incidence, and characterise soft tissue injury in rugby union players. DESIGN: A systematic search of electronic databases was performed. The search strategy combined terms covering: training volume and injury, and rugby union, and players of all levels. DATA SOURCES: Medline, SPORTDiscus, Web of Science, Embase, PubMed. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Studies were included if they reported: male rugby union players, a clear definition of a rugby union injury, the amount of training volume undertaken by participants, and epidemiological data for soft-tissue injuries including the number or incidence...
October 8, 2016: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28514926/trunk-muscle-activity-patterns-and-motion-patterns-of-patients-with-motor-complete-spinal-cord-injury-at-t8-and-t10-walking-with-different-un-powered-exoskeletons
#7
Xinyu Guan, Shengzheng Kuai, Linhong Ji, Rencheng Wang, Run Ji
OBJECTIVE: The aim of this study was to explore how neurological injured levels of spinal cord affect the performance of patients walking with different un-powered exoskeletons. STUDY DESIGN: Case series observational study. SETTING: Gait and Motion Analysis Laboratory at the National Research Center Rehabilitation Technical Aids. METHODS: Electromyography and motion data from two subjects with complete spinal cord injury at T10 and T8 walking with un-powered exoskeletons were collected simultaneously...
May 17, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28504066/the-association-of-recreational-and-competitive-running-with-hip-and-knee-osteoarthritis-a-systematic-review-and-meta-analysis
#8
Eduard Alentorn-Geli, Kristian Samuelsson, Volker Musahl, Cynthia L Green, Mohit Bhandari, Jón Karlsson
Study Design Systematic review and meta-analysis. Background Running is a healthy and popular activity worldwide, but data regarding its association with osteoarthritis (OA) are conflicting. Objectives To evaluate the association of hip and knee OA with running and to explore the influence of running intensity on this association. Methods PubMed, EMBASE and Cochrane Library databases were used to identify studies investigating the occurrence of OA of the hip and/or knee among runners. Studies comparing this occurrence between runners and controls (sedentary, non-running individuals) were meta-analyzed...
May 13, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28503539/differences-in-pes-planus-and-pes-cavus-subtalar-eversion-inversion-before-and-after-prolonged-running-using-a-two-dimensional-digital-analysis
#9
Charlotte Sinclair, Ulla Svantesson, Rita Sjöström, Marie Alricsson
In sports, there is a constant discussion about the hyper-pronation and supination of the foot during loading and its relation to injuries or discomfort. The purpose of the present study was to investigate the possible differences in the subtalar joint in the midstance phase of running, between individuals with Pes Planus and Pes Cavus, after 5 min and 45 min of running. Thirty-four subjects, meeting the requirements for Pes Planus (30 feet) and Pes Cavus (35 feet), according to the criteria for Medial Longitudinal Arch-angle, were included in the study...
April 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28503379/a-public-dataset-of-running-biomechanics-and-the-effects-of-running-speed-on-lower-extremity-kinematics-and-kinetics
#10
Reginaldo K Fukuchi, Claudiane A Fukuchi, Marcos Duarte
BACKGROUND: The goals of this study were (1) to present the set of data evaluating running biomechanics (kinematics and kinetics), including data on running habits, demographics, and levels of muscle strength and flexibility made available at Figshare (DOI: 10.6084/m9.figshare.4543435); and (2) to examine the effect of running speed on selected gait-biomechanics variables related to both running injuries and running economy. METHODS: The lower-extremity kinematics and kinetics data of 28 regular runners were collected using a three-dimensional (3D) motion-capture system and an instrumented treadmill while the subjects ran at 2...
2017: PeerJ
https://www.readbyqxmd.com/read/28499137/a-comparison-of-the-ground-reaction-force-frequency-content-during-rearfoot-and-non-rearfoot-running-patterns
#11
Allison H Gruber, W Brent Edwards, Joseph Hamill, Timothy R Derrick, Katherine A Boyer
Running with a non-rearfoot pattern has been claimed to reduce injury risk because the impact peak in the vertical ground reaction force (GRF) is visually absent in the time-domain compared with a rearfoot pattern. However, running results in a rapid deceleration of the lower extremity segments immediately following initial contact with the ground, regardless of footfall pattern. Therefore, the frequency content of the GRF is expected to contain evidence of this collision. The purpose of the present study was to characterize the waveform components of the GRF generated during the impact phase by habitual rearfoot and habitual non-rearfoot pattern groups using the continuous wavelet transform...
April 28, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28497343/bdnf-contributes-to-spinal-long-term-potentiation-and-mechanical-hypersensitivity-via-fyn-mediated-phosphorylation-of-nmda-receptor-glun2b-subunit-at-tyrosine-1472-in-rats-following-spinal-nerve-ligation
#12
Song Li, Jie Cai, Zhi-Bo Feng, Zi-Run Jin, Bo-Heng Liu, Hong-Yan Zhao, Hong-Bo Jing, Tian-Jiao Wei, Guan-Nan Yang, Ling-Yu Liu, Yan-Jun Cui, Guo-Gang Xing
Previously we have demonstrated that brain-derived neurotrophic factor (BDNF) contributes to spinal long-term potentiation (LTP) and pain hypersensitivity through activation of GluN2B-containing N-methyl-D-aspartate (GluN2B-NMDA) receptors in rats following spinal nerve ligation (SNL). However, the molecular mechanisms by which BDNF impacts upon GluN2B-NMDA receptors and spinal LTP still remain unclear. In this study, we first documented that Fyn kinase-mediated phosphorylation of GluN2B subunit at tyrosine 1472 (pGluN2B(Y1472)) was involved in BDNF-induced spinal LTP and pain hypersensitivity in intact rats...
May 11, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28492199/an-infant-case-of-intraoral-penetrating-injury-with-a-toothbrush-causing-retropharyngeal-and-upper-mediastinal-emphysema
#13
Kei Jitsuiki, Ayako Hashimoto, Toshihiko Yoshizawa, Youichi Yanagawa
A 2-year-old male child who was running and fell with a toothbrush in his mouth suffered an injury to the inside of his right cheeks. His mother noticed that the toothbrush had impaled his mouth, and removed it. On arrival, a wound was observed on the right cheeks and palate. His general condition was good. However, computed tomography revealed emphysema from the left side of epipharynx to the upper mediastinum. This patient shows the importance of not only checking the medical history and performing a physical examination but also performing an imaging examination...
April 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28491886/the-effect-of-the-number-of-carries-among-college-running-backs-on-future-injury-risk-and-performance-in-the-national-football-league
#14
Matthew J Kraeutler, John W Belk, Eric C McCarty
BACKGROUND: There has been speculation that running backs with an excessive number of carries in college are less likely to be successful in the National Football League (NFL). PURPOSE: To determine whether there is a correlation between number of carries by college running backs and future performance and injury risk in the NFL. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: Using the ESPN archives of National Collegiate Athletic Association and NFL running backs, the following inclusion criteria were used: running backs who played their last college season from 1999 through 2012 and who were drafted in the first 4 rounds of the NFL draft following their college career...
April 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28484983/ischemic-preconditioning-in-the-intensive-care-unit
#15
REVIEW
Maranatha Ayodele, Sebastian Koch
Preconditioning is the premise that controlled preemptive exposure to sub-lethal doses of a stressor and can condition an organism or organ to later withstand a lethal dose. This process relies on marshaling endogenous survival resources that have evolved as part of an organism's evolutionary struggle to overcome at times harsh environmental conditions. This preconditioning response occurs through activation of myriad complex mechanisms that run the gamut from alterations in gene expression to the de novo synthesis and post-translational modification of proteins, and it may occur across exposure to a wide variety of stressors (i...
June 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/28482203/transition-from-shod-to-barefoot-alters-dynamic-stability-during-running
#16
Antonis Ekizos, Alessandro Santuz, Adamantios Arampatzis
INTRODUCTION: Barefoot running recently received increased attention, with controversial results regarding its effects on injury risk and performance. Numerous studies examined the kinetic and kinematic changes between the shod and the barefoot condition. Intrinsic parameters such as the local dynamic stability could provide new insight regarding neuromuscular control when immediately transitioning from one running condition to the other. We investigated the local dynamic stability during the change from shod to barefoot running...
April 27, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28480026/exercise-training-provides-cardioprotection-by-activating-and-coupling-endothelial-nitric-oxide-synthase-via-a-%C3%AE-3-adrenergic-receptor-amp-activated-protein-kinase-signaling-pathway
#17
Larry A Barr, Jonathan P Lambert, Yuuki Shimizu, Lili A Barouch, Nawazish Naqvi, John W Calvert
Exercise training confers sustainable protection against ischemia/reperfusion injury. However, the mechanism by which this process occurs is not fully understood. Previously, it was shown that β3-adrenergic receptors (β3-ARs) play a critical role in regulating the activation of endothelial nitric oxide synthase (eNOS) in response to exercise and play a critical role in exercise-mediated cardioprotection. Intriguingly, a deficiency in β3-ARs led to increased myocardial injury following exercise training. The purpose of the current study was to determine mechanisms by which β3-ARs are linked to eNOS activation and to determine the mechanism responsible for the exacerbated ischemia/reperfusion injury displayed by β3-AR deficient (β3-AR KO) mice after exercise training...
January 2017: Medical Gas Research
https://www.readbyqxmd.com/read/28475999/prevalence-and-risk-factors-of-seizure-clusters-in-adult-patients-with-epilepsy
#18
Baibing Chen, Hyunmi Choi, Lawrence J Hirsch, Austen Katz, Alexander Legge, Rebecca A Wong, Alfred Jiang, Kenneth Kato, Richard Buchsbaum, Kamil Detyniecki
PURPOSE: In the current study, we explored the prevalence of physician-confirmed seizure clusters. We also investigated potential clinical factors associated with the occurrence of seizure clusters overall and by epilepsy type. METHODS: We reviewed medical records of 4116 adult (≥16years old) outpatients with epilepsy at our centers for documentation of seizure clusters. Variables including patient demographics, epilepsy details, medical and psychiatric history, AED history, and epilepsy risk factors were then tested against history of seizure clusters...
July 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28474244/-morel-lavall%C3%A3-e-lesion-severely-injured-13%C3%A2-year%C3%A2-old-after-being-run-over
#19
F C F Schmitt, T Brenner, S Hofer, M A Weigand, P A Grützner, U Kneser, T Kremer, J Franke, U Müller
Accidents in which a person is run over are often associated with multiple serious injuries. Immediate bleeding control is crucial. Pressure and shear stress at the borders of subcutaneous tissue to the muscle fascia can cause hypoperfusion and the emergence of blood-filled cavities that are associated with a high risk of infection and necrosis, a so-called Morel-Lavallée lesion. Insufficient therapy can lead to local complications and furthermore to live-threatening sepsis.
May 4, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/28473366/compensating-for-loss-running-on-one-tibialis-anterior
#20
Richard A C Dimock, Edward John Christopher Dawe, Olusegun Aiyenuro
Rupture of the tibialis anterior (TA) tendon is rare and may be either traumatic or spontaneous. TA is the main ankle dorsiflexor, providing 80% of the power, as well as contributing to inversion of the foot. We describe a case of an 84-year-old male who was incidentally diagnosed with absence of his left TA at age 46 while preparing for his first-ever marathon. There was no history of specific injury to this tendon. He subsequently went on to lead an active sporting life, completing over 20 marathons with a best time of 3 hours 12 min...
May 3, 2017: BMJ Case Reports
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