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https://www.readbyqxmd.com/read/29239887/incidence-of-sexually-transmitted-infections-before-and-after-pre-exposure-prophylaxis-for-hiv-a-cohort-study
#1
Vinh-Kim Nguyen, Zoë R Greenwald, Helen Trottier, Martha Cadieux, Alexandre Goyette, Mariève Beauchemin, Louise Charest, Danièle Longpré, Stéphane Lavoie, Hermione Gbego Tossa, Réjean Thomas
OBJECTIVE: Use of Pre-Exposure Prophylaxis (PrEP) for HIV raises concerns about sexually transmitted infection (STI) incidence due to decreased condom use among men who have sex with men (MSM). This study examines whether PrEP is associated with STIs in the 12-months following PrEP prescription relative to the 12-months prior to PrEP and if STI rates are higher among PrEP users relative to individuals receiving Post-Exposure Prophylaxis (PEP). DESIGN: Retrospective cohort study including PrEP users with >12 months of follow-up before PrEP prescription and individuals receiving PEP from 2010-2015 at Clinique l'Actuel (Montréal, Canada)...
December 12, 2017: AIDS
https://www.readbyqxmd.com/read/29239677/effects-of-kinect-adventures-games-versus-conventional-physical-therapy-on-postural-control-in-elderly-people-a-randomized-controlled-trial
#2
Jéssica Maria Ribeiro Bacha, Gisele Cristine Vieira Gomes, Tatiana Beline de Freitas, Larissa Alamino Pereira Viveiro, Keyte Guedes da Silva, Géssika Costa Bueno, Eliana Maria Varise, Camila Torriani-Pasin, Angélica Castilho Alonso, Natalia Mariana Silva Luna, Júlia Maria D'Andrea Greve, José Eduardo Pompeu
OBJECTIVE: To compare the effectiveness of Kinect Adventures games versus conventional physiotherapy to improve postural control (PC), gait, cardiorespiratory fitness, and cognition of the elderly. In addition, we evaluated the safety, acceptability, and adherence to the interventions. MATERIALS AND METHODS: The study was a randomized clinical trial in which 46 elderly individuals were selected, mean age 69.3 (5.34) years. Participants were allocated to the Kinect Adventures Training Group (KATG) or the Conventional Physical Therapy Group (CPTG), 23 individuals in each group...
December 14, 2017: Games for Health
https://www.readbyqxmd.com/read/29239029/the-meaning-and-experience-of-stress-among-supported-employment-clients-with-mental-health-problems
#3
Christine Besse, Daniel Poremski, Vincent Laliberté, Eric Latimer
Many clinicians are concerned that competitive work may cause excessive stress for people with severe mental health problems. Individual Placement and Support (IPS) is acknowledged as the most effective model of supported employment for this population. The manner in which IPS clients define and experience employment-related stress is poorly understood. This qualitative study aims to explore how people with mental health problems receiving IPS services define and experience employment-related stress. We purposively sampled and interviewed 16 clients of an IPS programme, who had been competitively employed for more than 1 month...
December 13, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/29238748/non-motor-symptoms-in-progressive-supranuclear-palsy-prevalence-and-severity
#4
Fabiana Giada Radicati, Pablo Martinez Martin, Chiara Fossati, Kallol Ray Chaudhuri, Margherita Torti, Carmen Rodriguez Blazquez, Laura Vacca, Fabrizio Stocchi
NMSs have been extensively studied in PD patients but not in other forms of parkinsonism such as Progressive Supranuclear Palsy (PSP). The primary objective of this study was to analyze the frequency, severity and the type of non-motor symptoms (NMS) in PSP patients using the non-motor symptoms scale (NMSS). The secondary objective was to differentiate NMS between PSP and Parkinson's disease (PD). We enrolled in this cross-sectional study 50 consecutive PSP and 100 matched Parkinson's disease (PD) patients, in the proportion PSP/PD = 1/2, matched in age, sex, and disease duration...
2017: NPJ Parkinson's Disease
https://www.readbyqxmd.com/read/29238393/influence-of-severe-carotid-stenosis-on-cognition-depressive-symptoms-and-quality-of-life
#5
Elina Pucite, Ildze Krievina, Evija Miglane, Renars Erts, Dainis Krievins
Background: Carotid artery disease is not just a causal risk factor of ischemic stroke, but may predispose patients to depressive symptoms and low health related quality of life (HRQoL). Objectives: The objectives of the present study were to assess the association between severe carotid artery stenosis (CAS) and cognitive impairment, frequency of depressive symptoms and status of HRQoL. Methods: Cross - sectional study involved 55 patients with severe CAS and 54 patients with lower extremity peripheral artery disease (PAD)...
2017: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/29225467/altered-emotional-recognition-and-expression-in-patients-with-parkinson-s-disease
#6
Yazhou Jin, Zhiqi Mao, Zhipei Ling, Xin Xu, Zhiyuan Zhang, Xinguang Yu
Background: Parkinson's disease (PD) patients exhibit deficits in emotional recognition and expression abilities, including emotional faces and voices. The aim of this study was to explore emotional processing in pre-deep brain stimulation (pre-DBS) PD patients using two sensory modalities (visual and auditory). Methods: Fifteen PD patients who needed DBS surgery and 15 healthy, age- and gender-matched controls were recruited as participants. All participants were assessed by the Karolinska Directed Emotional Faces database 50 Faces Recognition test...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29224768/newborn-hearing-screening-failure-and-maternal-factors-during-pregnancy
#7
Yehuda Schwarz, Gabriel N Kaufman, Sam J Daniel
OBJECTIVE: Temporary conductive hearing loss due to amniotic fluid accumulation in the middle ear cavity may lead to failure (false positive) in newborn hearing screening tests. The aim of this study was to identify whether amniotic fluid index has association with failure of the initial newborn otoacoustic emission (OAE) screening test. METHODS: A cohort study in a tertiary hospital center (Royal Victoria Hospital, Montréal) was constructed from 70 newborns that failed the OAE test, but passed a subsequent auditory brainstem response (ABR) test, and 75 randomly selected newborns that passed initial otoacoustic emission testing...
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29224579/wilder-penfield-sir-arthur-currie-and-the-montreal-neurological-institute
#8
R Mark Sadler
Wilder Penfield and the Montreal Neurological Institute (MNI) are inextricably linked. It was Penfield's unique idea to create a building with an academic atmosphere wherein basic neuroscience and clinical care of neurological patients would benefit from interaction and mutual support. It is clear that without Penfield that there would be no MNI; however, the role of another Canadian icon, Sir Arthur Currie, in the development of the MNI has heretofore been barely mentioned. The thesis of this paper is that Currie had a critical role in the gestation of the MNI that has generally been ignored...
December 11, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29224114/coated-platelet-trends-predict-short-term-clinical-outcomeafter-subarachnoid-hemorrhage
#9
Bappaditya Ray, Vijay M Pandav, Eleanor A Mathews, David M Thompson, Lance Ford, Lori K Yearout, Bradley N Bohnstedt, Shuchi Chaudhary, George L Dale, Calin I Prodan
Aneurysmal subarachnoid hemorrhage (aSAH) is associated with high socio-economic burden. Prothrombotic states of early brain injury (EBI) and delayed cerebral ischemia (DCI) after aSAH determine morbidity and mortality. To understand how activated platelets might contribute to such prothrombotic states, we studied trends in coated-platelets during EBI and DCI periods. Serial blood samples from a prospective cohort of aSAH patients were collected and assayed for coated-platelet levels. Patient's coated-platelet level during post-hospital discharge follow-up served as an estimate of baseline...
December 9, 2017: Translational Stroke Research
https://www.readbyqxmd.com/read/29222350/leflunomide-use-during-pregnancy-and-the-risk-of-adverse-pregnancy-outcomes
#10
Anick Bérard, Jin-Ping Zhao, Irene Shui, Susan Colilla
OBJECTIVES: Leflunomide is known to be embryotoxic and teratogenic in rodents. However, there is less evidence in humans. We quantified the risk of major congenital malformation (MCM), prematurity, low birth weight (LBW) and spontaneous abortion associated with leflunomide exposure during pregnancy in humans. METHODS: From a cohort of 289 688 pregnancies in Montreal, Quebec, Canada, from 1998 to 2015, first-trimester leflunomide exposure and other antirheumatic drug exposures were studied for their association with MCM and spontaneous abortions...
December 8, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29217231/risk-factors-for-radial-to-femoral-artery-pressure-gradient-in-patients-undergoing-cardiac-surgery-with-cardiopulmonary-bypass
#11
Vincent Bouchard-Dechêne, Pierre Couture, Antonio Su, Alain Deschamps, Yoan Lamarche, Georges Desjardins, Sylvie Levesque, André Y Denault
OBJECTIVE: To identify risk factors associated with radial-to-femoral pressure gradient during cardiac surgery with cardiopulmonary bypass (CPB). DESIGN: This is a retrospective, observational study. SETTING: Single specialized cardiothoracic hospital in Montreal, Canada. PARTICIPANTS: Consecutive patients that underwent heart surgery with CPB between 2005 and 2015 (n = 435). INTERVENTIONS: None...
September 15, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29209200/smart-aging-platform-for-evaluating-cognitive-functions-in-aging-a-comparison-with-the-moca-in-a-normal-population
#12
Sara Bottiroli, Cristina Tassorelli, Marialisa Lamonica, Chiara Zucchella, Elena Cavallini, Sara Bernini, Elena Sinforiani, Stefania Pazzi, Paolo Cristiani, Tomaso Vecchi, Daniela Tost, Giorgio Sandrini
Background: Smart Aging is a Serious games (SGs) platform in a 3D virtual environment in which users perform a set of screening tests that address various cognitive skills. The tests are structured as 5 tasks of activities of daily life in a familiar environment. The main goal of the present study is to compare a cognitive evaluation made with Smart Aging with those of a classic standardized screening test, the Montreal Cognitive Assessment (MoCA). Methods: One thousand one-hundred thirty-one healthy adults aged between 50 and 80 (M = 64...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29206893/the-cerebellar-cognitive-affective-schmahmann-syndrome-scale
#13
Franziska Hoche, Xavier Guell, Mark G Vangel, Janet C Sherman, Jeremy D Schmahmann
Cerebellar cognitive affective syndrome (CCAS; Schmahmann's syndrome) is characterized by deficits in executive function, linguistic processing, spatial cognition, and affect regulation. Diagnosis currently relies on detailed neuropsychological testing. The aim of this study was to develop an office or bedside cognitive screen to help identify CCAS in cerebellar patients. Secondary objectives were to evaluate whether available brief tests of mental function detect cognitive impairment in cerebellar patients, whether cognitive performance is different in patients with isolated cerebellar lesions versus complex cerebrocerebellar pathology, and whether there are cognitive deficits that should raise red flags about extra-cerebellar pathology...
December 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29204128/the-art-gallery-test-a-preliminary-comparison-between-traditional-neuropsychological-and-ecological-vr-based-tests
#14
Pedro Gamito, Jorge Oliveira, Daniyal Alghazzawi, Habib Fardoun, Pedro Rosa, Tatiana Sousa, Ines Maia, Diogo Morais, Paulo Lopes, Rodrigo Brito
Ecological validity should be the cornerstone of any assessment of cognitive functioning. For this purpose, we have developed a preliminary study to test the Art Gallery Test (AGT) as an alternative to traditional neuropsychological testing. The AGT involves three visual search subtests displayed in a virtual reality (VR) art gallery, designed to assess visual attention within an ecologically valid setting. To evaluate the relation between AGT and standard neuropsychological assessment scales, data were collected on a normative sample of healthy adults (n = 30)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29204030/symptoms-of-neurotoxicity-among-carpenters-living-in-rural-ecuador-a-population-based-study-the-atahualpa-project
#15
Oscar H Del Brutto, Robertino M Mera, Ani Reich de Amador, Mauricio Zambrano, Pablo R Castillo
Background: There is no information on the prevalence of symptoms related to neurotoxicity among carpenters working in underserved populations. To assess the magnitude of the problem, we conducted a population-based study in Atahualpa, a rural Ecuadorian village, where most men work as carpenters under poor safety conditions. Methods: All men aged 40-75 years living in Atahualpa were identified during a door-to-door survey and evaluated with a general demographic questionnaire, the Q16 questionnaire, the depression axis of the Depression Anxiety Stress Scale-21, and the Montreal Cognitive Assessment (MoCA)...
October 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29201182/the-efficacy-of-gastrodin-in-combination-with-folate-and-vitamin-b12-on-patients-with-epilepsy-after-stroke-and-its-effect-on-hmgb-1-il-2-and-il-6-serum-levels
#16
Hao Zhou, Nuan Wang, Lei Xu, Hongli Huang, Chunyu Yu
This study evaluated the efficacy of gastrodin in combination with folate (FOL) and vitamin-B12 (V-B12) on patients with epilepsy after stroke (EAS) and its effect on high-mobility group protein B1 (HMGB-1), interleukin-1 (IL-1), and IL-6 serum levels. The clinical data of 92 EAS patients admitted for treatment between April, 2014 and March, 2016 were collected. These patients were randomly divided into control and observation groups (n=46 each) using computer software. Patients in the control group were administered only regular antiepileptic drugs, whereas observation group patients also received a combination of gastrodin, FOL and V-B12...
November 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29197528/social-capital-and-obesity-among-adults-longitudinal-findings-from-the-montreal-neighborhood-networks-and-healthy-aging-panel
#17
Yun-Hsuan Wu, Spencer Moore, Laurette Dube
Curbing the worldwide increase in obesity requires upstream social interventions that modify the environment in which obesity emerges. Recent studies have suggested that social capital and networks may influence a person's risk of obesity. Yet, few longitudinal studies have assessed whether social capital and networks reduce obesity risk in adult populations. In this study, the data come from three waves (2008, 2010, and 2013) of the Montreal Neighborhood Networks and Health Aging Panel (N=2606). Self-reported height and weight were used to calculate body mass index (BMI) with obesity defined as a BMI>30...
November 29, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29197258/prevalence-of-mild-cognitive-impairment-and-its-subtypes-in-community-dwelling-residents-aged-65-years-or-older-in-guangzhou-china
#18
Dongping Rao, Xiong Luo, Muni Tang, Yin Shen, Ruoyan Huang, Junchang Yu, Jianjuan Ren, Xiaoying Cheng, Kangguang Lin
BACKGROUND: Prevalence of mild cognitive impairment (MCI) has been reported substantial variations, and mostly in Western countries. Less is known about MCI in the south of China. The study is to estimate the prevalence of MCI and its subtypes in residents aged 65year or older in community-dwelling residents of Guangzhou, China. METHODS: The study was a community-based, cross-sectional study conducted in rural and urban areas of Guangzhou between April and October 2009...
November 20, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29195763/revisiting-the-link-between-depression-symptoms-and-high-school-dropout-timing-of-exposure-matters
#19
Véronique Dupéré, Eric Dion, Frédéric Nault-Brière, Isabelle Archambault, Tama Leventhal, Alain Lesage
PURPOSE: Recent reviews concluded that past depression symptoms are not independently associated with high school dropout, a conclusion that could induce schools with high dropout rates and limited resources to consider depression screening, prevention, and treatment as low-priority. Even if past symptoms are not associated with dropout, however, it is possible that recent symptoms are. The goal of this study was to examine this hypothesis. METHODS: In 12 disadvantaged high schools in Montreal (Canada), all students at least 14 years of age were first screened between 2012 and 2015 (Nscreened = 6,773)...
November 28, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29195729/orthostatic-hypotension-in-parkinson-disease-impact-on-health-care-utilization
#20
Aristide Merola, Russell P Sawyer, Carlo Alberto Artusi, Ritika Suri, Zoe Berndt, Jose' Ricardo Lopez-Castellanos, Jennifer Vaughan, Joaquin A Vizcarra, Alberto Romagnolo, Alberto J Espay
INTRODUCTION: Orthostatic hypotension (OH) represents a frequent yet overlooked source of disability in Parkinson disease (PD). In particular, its impact on health care utilization has been insufficiently examined. We sought to determine the differential health care utilization in PD patients with (PDOH+) and without OH (PDOH-). METHODS: We quantified the emergency room (ER) visits, hospitalizations, outpatient clinic evaluations, phone calls, and e-mails from PD patients on whom supine and orthostatic blood pressure (BP) measurements were obtained during routine clinical practice between June 2013 and July 2016...
November 28, 2017: Parkinsonism & related Disorders
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