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https://www.readbyqxmd.com/read/29139591/mr-imaging-appearance-of-noncalcified-and-calcified-dcis
#1
Andrew Scott-Moncrieff, Megan E Sullivan, Ellen B Mendelson, Lilian Wang
To evaluate the MR appearance of noncalcified ductal carcinoma in situ (DCIS), with comparison to calcified DCIS. A retrospective, IRB-approved review of all DCIS diagnosed via MR biopsy between 2007 and 2011 was performed. DCIS was categorized as noncalcified based on the absence of calcifications on mammography and specimen radiography. MR morphology (focus, mass, nonmass enhancement [NME]) and enhancement kinetics (initial and delayed) for noncalcified DCIS were recorded and compared based on nuclear grade (1-3), size (<1...
November 15, 2017: Breast Journal
https://www.readbyqxmd.com/read/29131504/balloon-pin-hole-rupture-during-percutaneous-coronary-intervention-for-recurrent-calcified-in-stent-restenosis-a-case-report
#2
Nobuhiro Murata, Tadateru Takayama, Takafumi Hiro, Atsushi Hirayama
Percutaneous coronary intervention (PCI) for patients with in-stent restenosis (ISR) is generally considered safe and effective. However, due to increased tissue hardness, PCI for calcified intra-stent ISR is technically challenging. Here, we report severe angioplasty-related complications in a patient presenting with calcified, recurrent ISR following PCI. After receiving drug-coated balloon (DCB) angioplasty for an initial ISR, the patient developed recurrent ISR during the follow-up period. Intravascular imaging revealed intra-stent calcifications and balloon angioplasty was subsequently performed...
November 13, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29128426/detection-of-early-changes-in-the-coronary-artery-microstructure-after-heart-transplantation-a-prospective-optical-coherence-tomography-study
#3
Tor Skibsted Clemmensen, Niels Ramsing Holm, Hans Eiskjær, Lars Jakobsen, Katrine Berg, Omeed Neghabat, Brian Bridal Løgstrup, Evald Høj Christiansen, Jouke Dijkstra, Christian Juhl Terkelsen, Michael Maeng, Steen Hvitfeldt Poulsen
BACKGROUND: Optical coherence tomography (OCT) enables in-vivo cardiac allograft vasculopathy (CAV) microstructure characterization. Early coronary artery microstructure changes after heart transplantation (HTx) may provide valuable mechanistic information regarding CAV development. Our in this study was to describe and characterize changes in the coronary artery microstructure during the first year after HTx using serial OCT scans. METHODS: Twenty-six patients were enrolled at routine baseline coronary angiography 3 months after HTx...
October 23, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29121522/effects-of-vitamin-k-antagonist-on-aortic-valve-degeneration-in-non-valvular-atrial-fibrillation-patients-prospective-4-year-observational-study
#4
Kazuhiro Yamamoto, Yukihiro Koretsune, Takashi Akasaka, Akira Kisanuki, Nobuyuki Ohte, Takashi Takenaka, Masaaki Takeuchi, Kiyoshi Yoshida, Kazunori Iwade, Yuji Okuyama, Yutaka Hirano, Yasuharu Takeda, Yasumasa Tsukamoto, Yoshiharu Kinugasa, Satoshi Nakatani, Takashi Sakamoto, Katsuomi Iwakura, Takashi Sozu, Tohru Masuyama
BACKGROUND: The prevalence of atrial fibrillation (AF) is high in elder subjects. Our previous observational study suggested that vitamin K antagonist (VKA) promotes aortic valve degeneration, a principal cause of aortic stenosis in the elderly, and that angiotensin receptor blocker (ARB) attenuates its progression. This study aimed to prospectively investigate these observations in non-valvular AF patients. METHODS: Of enrolled 430 patients with calcification on no or one aortic valve leaflet, all of the planned 4-year follow-up data were obtained in 122 non-valvular AF patients treated with warfarin (warfarin group) and 101 patients with cardiovascular diseases and without AF and prescription of warfarin (non-warfarin group)...
November 6, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/29116910/treatment-of-femoropopliteal-lesions-with-the-angiosculpt-scoring-balloon-results-from-the-heidelberg-panther-registry
#5
Ira Lugenbiel, Michaela Grebner, Qianxing Zhou, Anna Strothmeyer, Britta Vogel, Rita Cebola, Oliver Müller, Bernadett Brado, Marc Mittnacht, Benedikt Kohler, Hugo Katus, Erwin Blessing
BACKGROUND: Treatment of calcified femoropopliteal lesions remains challenging, even in the era of drug-eluting balloon angioplasty. Lesion recoil and dissections after standard balloon angioplasty in calcific lesions often require subsequent stent implantation. Additionally, poor patency rates in calcified lesions despite the use of drug-eluting balloons may be due to the limited penetration depth of the antiproliferative drug in the presence of vascular calcium deposits. Therefore, preparation of calcified lesions with the AngioSculpt™ scoring balloon might be a valuable option either as a stand-alone treatment, followed by drug-eluting balloon angioplasty or prior to subsequent stent deployment...
November 8, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/29113866/intravascular-ultrasound-enhances-the-safety-of-rotational-atherectomy
#6
REVIEW
Kenichi Sakakura, Kei Yamamoto, Yousuke Taniguchi, Yoshimasa Tsurumaki, Shin-Ichi Momomura, Hideo Fujita
Intravascular ultrasound (IVUS) is mainly used in PCI to treat complex lesions, such as left main bifurcation, chronic total occlusion and calcified lesions. Although IVUS yields useful information such as the presence of napkin-ring calcification, the role of IVUS in rotational atherectomy (RA) is not fully appreciated. Recently, since the deliverability and crossability of IVUS catheters have improved, IVUS should be attempted before RA. Even if the IVUS catheter cannot cross the lesion, IVUS provides information just proximal to the target lesion, which would be useful in the selection of the appropriate guidewire and burr size...
September 23, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29113208/calcifying-cystic-odontogenic-tumor-accompanied-by-a-dentigerous-cyst-a-case-report
#7
Shoko Gamoh, Hironori Akiyama, Chisato Furukawa, Yuki Matsushima, Tomio Iseki, Masahiro Wato, Akio Tanaka, Shosuke Morita, Kimishige Shimizutani
A calcifying cystic odontogenic tumor (CCOT) is a proliferation of odontogenic epithelium and scattered nests of ghost cells and calcifications that may form the lining of a cyst, or present as a solid mass. It was previously described by Gorlin et al in 1962 as a calcifying odontogenic cyst. Dentigerous cysts are developmental odontogenic jaw cysts, commonly manifesting in the second and third decades of life. The present study reports an asymptomatic case in a 13-year-old boy who was referred to the outpatient clinic of the Osaka Dental University Hospital (Osaka, Japan) for additional investigation of an area of radiolucency in the lower right jaw...
November 2017: Oncology Letters
https://www.readbyqxmd.com/read/29103930/superior-mesenteric-artery-calcification-is-associated-with-cardiovascular-risk-factors-systemic-calcified-atherosclerosis-and-increased-mortality
#8
Timothy C Lin, C Michael Wright, Michael H Criqui, Matthew A Allison
BACKGROUND: Atherosclerosis is a major risk factor for morbidity and mortality. However, epidemiologic data are sparse regarding risk factors for superior mesenteric artery calcification (SMAC), the association between SMAC and disease in other arterial beds, or the independent contribution of SMAC to risk of mortality. The objective of this study was to test the hypothesis that presence and extent of SMAC are associated with cardiovascular disease (CVD) risk factors, calcification in other arterial beds, and both cardiovascular and all-cause mortality, independent of classic risk factors and calcification in other arterial beds...
November 2, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29098547/new-data-from-pdfgb-ret-ret-mutant-mice-might-lead-to-a-paradoxical-association-between-brain-calcification-pericytes-recruitment-and-bbb-integrity
#9
Denis A P Moura, Roberta R Lemos, João R M Oliveira
Data of mice with PDGF-B-truncating mutation (Pdgfb (ret/ret)) from different research groups indicate that the malfunction of this protein leads to reduced pericyte recruitment, loss of Blood-Brain Barrier (BBB) integrity and bilateral brain calcification. This makes these mice important models for Primary Brain Calcification and pericyte-BBB correlation studies. The global brain pericyte count is reduced in Pdgfb (ret/ret) mice, with higher BBB permeability. We have overlapped the data from other research groups into a figure to further analyze the findings...
November 2, 2017: Journal of Molecular Neuroscience: MN
https://www.readbyqxmd.com/read/29097437/associations-of-endogenous-estradiol-and-testosterone-levels-with-plaque-composition-and-risk-of-stroke-in-subjects-with-carotid-atherosclerosis
#10
Marija Glisic, Blerim Mujaj, Oscar L Rueda-Ochoa, Eralda Asllanaj, Joop S Laven, Maryam Kavousi, M Kamran Ikram, Meike W Vernooij, M Arfan Ikram, Oscar H Franco, Daniel Bos, Taulant Muka
Rationale: Sex steroids may play a role in plaque composition and in stroke incidence. Objective: To study the associations of endogenous estradiol and testosterone with carotid plaque composition in elderly men and postmenopausal women with carotid atherosclerosis, as well as with risk of stroke in this population. Methods and Results: Data of 1023 postmenopausal women and 1124 men (≥45 years) with carotid atherosclerosis, from prospective population-based Rotterdam Study, were available. At baseline, total estradiol (TE) and total testosterone (TT) were measured...
November 2, 2017: Circulation Research
https://www.readbyqxmd.com/read/29096884/comparison-of-the-coronary-artery-calcium-score-and-number-of-calcified-coronary-plaques-for-predicting-patient-mortality-risk
#11
Yoav Arnson, Alan Rozanski, Heidi Gransar, John D Friedman, Sean W Hayes, Louise E Thomson, Balaji Tamarappoo, Piotr Slomka, Frances Wang, Guido Germano, Damini Dey, Daniel S Berman
Multiple coronary artery calcium (CAC) parameters have recently been proposed to improve risk prediction in patients with intermediate clinical risk based on CAC scoring, but outcome data that assess these variables are relatively sparse. We analyzed data from 11,633 consecutive asymptomatic patients undergoing CAC scanning that were followed for 8.8 ± 3.5 years for all-cause mortality (ACM). The patients who had coronary artery calcification were grouped by the number of calcified coronary plaques: 0, 1 to 5, 6 to 20, and >20 plaques...
September 18, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29095701/impact-of-motion-compensation-and-partial-volume-correction-for-sup-18-sup-f-naf-pet-ct-imaging-of-coronary-plaque
#12
Jacobo Cal-Gonzalez, Charalampos Harry Tsoumpas, Martin Lyngby Lassen, Sazan Rasul, Lorenz Koller, Marcus Hacker, Klaus P Schäfers, Thomas Beyer
Recent studies have suggested that <sup>18</sup>F-NaF-PET enables visualization and quantification of plaque micro-calcification in the coronary tree. However, PET imaging of plaque calcification in the coronary arteries is challenging because of the respiratory and cardiac motion as well as partial volume effects. The objective of this work is to implement an image reconstruction framework, which incorporates compensation for respiratory as well as cardiac motion (MoCo) and partial volume correction (PVC), for cardiac <sup>18</sup>F-NaF PET imaging in PET/CT...
November 2, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29093429/echocardiographic-assessment-of-cardiac-structural-and-functional-abnormalities-in-patients-with-end-stage-renal-disease-receiving-chronic-hemodialysis
#13
Hiroshi Matsuo, Kaoru Dohi, Hirofumi Machida, Hideyuki Takeuchi, Toshikazu Aoki, Hiroyuki Nishimura, Masashi Yasutomi, Michiharu Senga, Takehiko Ichikawa, Kentaro Kakuta, Yasuhide Mizutani, Akiko Tanoue, Naoki Isaka, Kazuki Oosugi, Sukenari Koyabu, Masato Sakurai, Yoshihisa Fukui, Hitoshi Kakimoto, Tadafumi Sugimoto, Takahiro Ohnishi, Tomohiro Murata, Eiji Ishikawa, Ryuji Okamoto, Tomomi Yamada, Toru Ogura, Yuki Nishimura, Takashi Tanigawa, Shinsuke Nomura, Masakatsu Nishikawa, Masaaki Ito
BACKGROUND: The aim of this study was to assess the echocardiographic characteristics of chronic hemodialysis (HD) patients with end-stage renal disease (ESRD) in a multicenter prospective cohort study.Methods and Results:Three hundred and fifteen patients with ESRD (67.9±10.6 years, 47.6% male) on chronic HD for ≥1 year were examined on transthoracic echocardiography, including Doppler-derived aortic valve area (AVA) measurement. Only 11.5% and 3.4% of all patients had normal left ventricular (LV) geometry and normal LV filling pattern, respectively...
October 31, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29093411/from-mitral-annular-calcification-to-calcified-amorphous-tumor
#14
Nozomi Toyokawa, Hiroyuki Okura, Yoshihiko Saito
No abstract text is available yet for this article.
November 1, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29092119/mir-92a-a-novel-potential-biomarker-of-rapid-aortic-valve-calcification
#15
Joseph Nader, Valérie Metzinger-Le Meuth, Pierre Maitrias, Jean-Régis Humbert, Benjamin Brigant, Christophe Tribouilloy, Laurent Metzinger, Thierry Caus
BACKGROUND: The study aim was to compare the tissular expression of microRNAs (miRs) in bicuspid and tricuspid valves, and to evaluate their use as potential novel biomarkers of aortic valve calcification in bicuspid valves. METHODS: A prospective single-center observational study was conducted on stenotic bicuspid and tricuspid human aortic valves. According to their potential role in valve vascular and valvular calcification, a decision was taken to include miR- 92a, miR-141, and miR-223 in this analysis...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29091092/three-dimensional-morphometry-of-collagen-fibrils-in-membranous-bone
#16
Mana Hashimoto, Noriyuki Nagaoka, Kaori Tabata, Tomoyo Tanaka, Ryuta Osumi, Naoya Odagaki, Toru Hara, Hiroshi Kamioka
The collagen network acts as a scaffold for calcification and its three-dimensional structure influences bone strength. It is therefore important to observe the collagen network in detail and three-dimensionally. In this study, we observed the collagen network of chick embryonic calvariae in membranous bone three-dimensionally using orthogonally arranged FIB-SEM. A 25 × 25 μm area of chick embryonic calvaria was observed at a high resolution (25 nm per pixel). The inside of the bone (i.e. the primary calcified tissue), the bone cells (i...
November 13, 2017: Integrative Biology: Quantitative Biosciences From Nano to Macro
https://www.readbyqxmd.com/read/29089685/use-of-multidetector-computed-tomography-angiography-of-upper-limb-circulation-in-patients-undergoing-coronary-artery-bypass-grafting-surgery
#17
Hasan B Altinsoy, Ozkan Alatas, Hidayet Kayancicek, Erhan Hafiz, Omer F Dogan
OBJECTIVE: This study aimed to evaluate the bilateral forehand circulation using a 64-channel multidetector computed tomography (MDCT) as a noninvasive method to define criteria for an upper extremity arterial anatomy and pathology prior to the use of arterial conduits. MATERIALS AND METHODS: Fifty-five patients with coronary artery disease who underwent total arterial coronary artery bypass grafting (CABG) were randomly selected for this prospective study. MDCT angiography was performed for 110 examinations of forearm and hand arterial anatomy...
July 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/29076298/a-challenging-case-of-calcific-myonecrosis-of-tibialis-anterior-and-hallucis-longus-muscles-with-a-chronic-discharging-wound
#18
Alethea My Tan, Charles Yuen Yung Loh, Metin Nizamoglu, Makarand Tare
The occurrence of calcific myonecrosis of the anterior compartment of the leg is rare. Common risk factors include a history of trauma, although little is known about the exact pathophysiology, latency period or triggering factors resulting in disease progression. Macroscopically, it begins with a single muscle being replaced by a fusiform calcified mass, which progresses peripherally. We present a rare case of a 7-year history of chronic discharging sinus overlying the site with protruding calcified muscle and discuss the senior author's wound management strategy and surgical considerations...
October 27, 2017: International Wound Journal
https://www.readbyqxmd.com/read/29073937/tumoral-calcinosis-in-the-cervical-spine-a-case-report-and-review-of-the-literature
#19
Rui Guo, Tatsuya Kurata, Tetsushi Kondo, Takao Imanishi, Tetsutaro Mizuno, Toshihiko Sakakibara, Yuichi Kasai
BACKGROUND: Tumoral calcinosis is rarely located in spine. A 55-year-old Japanese woman with cervical tumoral calcinosis is presented, along with a review of the literature relating to tumoral calcinosis in the spine. We discussed the etiology, diagnosis, and management of this condition. CASE PRESENTATION: We report a case of a patient with cervical tumoral calcinosis with end-stage renal disease. A computed tomography scan showed a lobulated, calcified mass around the right facet joint at the fourth-fifth cervical spine and calcifications were also observed in the right intervertebral foramens at fourth-fifth cervical spine and fifth-sixth cervical spine levels and the anterior wall of the spinal canal...
October 27, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29069932/lumbar-intravertebral-disc-herniation-secondary-to-idiopathic-calcific-discitis
#20
Ahmed-Ramadan Sadek, Christopher Dare, Stephen McGillion, Ali Nader-Sepahi, Vasileios Skiadas
Calcific discitis is a well recognized entity in the paediatric population but more recently has been increasingly reported in adults. It typically involves the lower thoracic vertebrae and is of unknown aetiology. Herniation of the calcified fragment is rare but typically occurs out through the annulus fibrosus into the canal space. Herein we describe the first reported case of calcific discitis involving the lumbar vertebrae with subsequent herniation of the calcified disc into and through the anterior aspect of the L5 vertebra...
October 26, 2017: British Journal of Neurosurgery
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