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calcification calcified

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https://www.readbyqxmd.com/read/28722701/susceptibility-weighted-with-quantitative-phase-magnetic-resonance-imaging-in-differentiation-of-various-stages-of-hemorrhage-and-calcification-in-female-pelvic-pathologies-a-preliminary-study
#1
Sakshi Khurana, Prativa Sahoo, Mukta Kapila, Swati Mittal, Manavita Mahajan, Indrajit Saha, Rakesh Kumar Gupta
BACKGROUND: The purposes of this study were to assess the value of phase for characterization of female pelvic lesions with hemorrhage in various stages and to differentiate them from calcified lesions at 3.0-T magnetic resonance imaging (MRI). METHODS: Forty-four female patients with hemorrhagic (n = 37) or calcified (n = 7) pelvic pathology underwent conventional MRI including susceptibility-weighted imaging with phase information. Hemorrhagic lesions were grouped into acute, subacute, and chronic, and calcified lesions were detected on the basis of conventional imaging findings...
July 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28722295/prevalence-correlates-and-impact-of-coronary-calcification-on-adverse-events-following-pci-with-newer-generation-des-findings-from-a-large-multiethnic-registry
#2
Robert S Copeland-Halperin, Usman Baber, Melissa Aquino, Anitha Rajamanickam, Swathi Roy, Choudhury Hasan, Nitin Barman, Jason C Kovacic, Pedro Moreno, Prakash Krishnan, Joseph M Sweeny, Roxana Mehran, George Dangas, Annapoorna S Kini, Samin K Sharma
OBJECTIVES: We sought to determine the prevalence, predictors, and clinical impact of target lesion calcification in patients undergoing percutaneous coronary intervention (PCI) with newer generation drug-eluting stents (DES) and devices. BACKGROUND: Coronary calcification is independently associated with adverse outcomes following PCI. While newer DES and contemporary devices are considered safer and more efficacious, their influence on outcomes following PCI of heavily calcified lesions is unknown...
July 19, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28720499/coronary-artery-disease-associated-gene-phactr1-modulates-severity-of-vascular-calcification-in-vitro
#3
Redouane Aherrahrou, Zouhair Aherrahrou, Heribert Schunkert, Jeanette Erdmann
Calcification of vessels is strongly associated with atherosclerosis and leads to coronary artery disease (CAD) and myocardial infarction (MI). Genome-wide association studies (GWAS) revealed several genes that are associated with and contribute to CAD/MI as well as coronary artery calcification (CAC); however, the underlying mechanisms are unknown. PHACTR1, which encodes phosphatase and actin regulator 1, is among these risk genes. The aim of this study was to functionally test whether Phactr1 regulates calcification in vitro using murine embryonic stem cell (mESC)-derived smooth muscle cells (SMCs)...
July 15, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28720119/calcified-amorphous-tumor-of-the-heart-with-mitral-annular-calcification-a-case-report
#4
Ryo Nakamaru, Hiroki Oe, Katsuomi Iwakura, Takafumi Masai, Kenshi Fujii
BACKGROUND: Calcified amorphous tumor of the heart is a rare, non-neoplastic cardiac mass characterized by nodular calcium in the background of amorphous degenerating fibrinous material. Clinical diagnosis of calcified amorphous tumor can be difficult, and current single imaging techniques do not specifically differentiate calcified amorphous tumor from other cardiac tumors such as calcified atrial myxoma, calcified thrombi, or vegetation. Complete surgical resection is the treatment of choice for both symptom improvement and prevention of embolization, as well as for pathological diagnosis...
July 18, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28718912/survival-of-atherosclerotic-calcifications-in-skeletonized-material-forensic-and-pathological-implications
#5
Lucie Biehler-Gomez, Annalisa Cappella, Elisa Castoldi, Laurent Martrille, Cristina Cattaneo
Atherosclerosis is a chronic inflammatory disease creating calcifying plaques in the arterial walls. Because its paleopathological diagnosis remains little studied on skeletal remains, its impact on forensic and archeological data is completely underestimated. Here, 24 skeletal remains from the Milano Cemetery Skeletal Collection have been studied to evaluate the chance of atherosclerotic calcification survival, retrieval, and identification. Through direct comparison with a known autopsy collection and literature, the identification and categorization of several types of calcifications were performed...
July 18, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28712720/manual-aspiration-thrombectomy-in-patients-with-acute-stroke-related-calcified-cerebral-emboli
#6
Esther Koh, Hyo Sung Kwak, Gyung-Ho Chung
OBJECTIVE: The aim of this study was to evaluate the effectiveness of mechanical aspiration thrombectomy (MAT) in patients with acute ischemic stroke from calcified cerebral emboli. METHODS: Procedural results were reviewed for acute stroke patients with clinically neurological deficits who underwent recanalization from October 2012 through September 2015. Initial imaging studies and cerebral angiography were analyzed. RESULTS: Of the total number of patients with acute stroke, 5 patients were confirmed to have acute ischemic stroke by calcified cerebral emboli...
July 13, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28709635/histopathological-investigation-of-intranodular-echogenic-foci-detected-by-thyroid-ultrasonography
#7
Suat Bilici, Ozgur Yigit, Firat Onur, Bahtiyar Hamit, Mehmet Ali Nazli, Feray Gunver, Yesim Karagoz
OBJECTIVE: To determine the predictability of sonography for detection of calcifications in thyroid nodules by histopathologic examination and to demonstrate the association between calcification pattern and malignancy. METHODS: We prospectively evaluated 81 dominant nodules from 81 patients. Thyroid glands were assessed preoperatively with thyroid ultrasonography, and the presence of sonographic calcification was specified as intranodular macro (coarse) and micro calcification...
July 5, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28701675/pathology-of-neointimal-calcification-in-very-late-restenosis-after-bare-metal-stent-implantation-for-superficial-femoral-artery
#8
Hiroyuki Jinnouchi, Katsumi Inoue, Yoshimitsu Soga, Yusuke Tomoi, Yohei Kobayashi, Seiichi Hiramori, Shinichi Shirai, Kenji Ando
A 60-year-old man, who had claudication in his right limb due to total occlusion of the right superficial femoral artery, received bare metal stents. Although the bare metal stents in the superficial femoral artery did not show restenosis 5 years after stent implantation, angiography revealed significant in-stent restenosis when he developed right critical limb ischemia at 8 years post implantation. Ballooning for in-stent lesions did not result in full expansion. His right limb was amputated above the knee due to progressive limb ischemia...
July 13, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28693828/inhibition-of-plaque-progression-and-promotion-of-plaque-stability-by-glucagon-like-peptide-1-receptor-agonist-serial-in%C3%A2-vivo-findings-from-imap-ivus-in-watanabe-heritable-hyperlipidemic-rabbits
#9
Mitsumasa Sudo, Yuxin Li, Takafumi Hiro, Tadateru Takayama, Masako Mitsumata, Masashi Shiomi, Masahiko Sugitani, Taro Matsumoto, Hiroyuki Hao, Atsushi Hirayama
BACKGROUND AND AIMS: Glucagon-like peptide-1 (GLP-1) is thought to inhibit development of aortic atherosclerosis and plaque formation. However, whether GLP-1 stabilizes fully developed atherosclerotic plaque or alters the complicated plaque composition remains unclarified. METHODS: Ten Watanabe heritable hyperlipidemic (WHHL) rabbits were divided into GLP-1 receptor agonist treatment group and control group. After confirmation of atherosclerotic plaques in brachiocephalic arteries by iMap intravascular ultrasound (iMAP-IVUS), GLP-1 receptor agonist lixisenatide was administered to WHHL rabbits at 30 nmoL/kg/day for 12 weeks by osmotic pump...
June 23, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28693296/mineralized-deposits-in-the-uterus-of-a-pig-without-pregnancy-loss
#10
Geon A Kim, Jun-Xue Jin, Anukul Taweechaipaisankul, Sanghoon Lee, Byung Il Yoon, Jongki Cho, Byeong Chun Lee
We reported a case of uterine calcification in the uterus of a pig without pregnancy loss. The recipient underwent cloned embryo transfer and the Cesarean section for safe delivery of cloned piglets. During the Cesarean section, 4 white, starlike, 2 x 2 x 2 cm, calcified structures were found within the endometrial cavity. Despite dystrophic calcification around placenta, healthy cloned piglets were produced successfully. To our knowledge, this is the first reported case of dystrophic calcification occurring within the uterus in a pregnant pig...
July 10, 2017: Journal of Veterinary Science
https://www.readbyqxmd.com/read/28680735/pilocytic-astrocytoma-a-rare-presentation-as-intraventricular-tumor
#11
Sidra Sattar, Naveed Z Akhunzada, Gohar Javed, Zeeshan Uddin, Yasir A Khan
BACKGROUND: Pilocytic astrocytoma (PA) is the most prevalent central nervous system (CNS) tumor in pediatric population and accounts for an approximate of 5-6% of all gliomas. This neoplasm can occur at all levels of the neuraxis, with majority (67%) arising in the cerebellum and optic pathway. PAs are World Health Organization Grade I tumors and are the most benign of all astrocytomas characterized by an excellent prognosis. Other differentials include subependymal giant cell astrocytoma (SEGA), ependymoma, meningioma, and low-grade gliomas such as pilocytic or diffuse astrocytoma; calcification is more commonly regarded as a feature of benign or slow-growing tumors...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28679511/traumatic-myositis-ossificans-circumscripta-moc
#12
Manel Landolsi, Tej Mrad
We report a case of a 29-year-old man who had been a victim of a public road accident. Four weeks later, the patient developed an isolated right thigh mass located ventrally in the distal one-third of the thigh. The mass was painful and associated with fever and inflammatory syndrome. Plain radiographs showed a bilateral calcified thickening of soft tissues with well-defined bony margins. Ultrasound objectified diffuse calcifications of soft tissues.CT scan-confirmed the diagnosis of myositis ossificans circumscripta, showing a bilateral thickening of the vastus intermedius chief of the quadriceps dotted with calcifications, extending along the femur axis...
July 5, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28677820/calcifying-epithelioma-of-malherbe-pilomatrixoma-clinical-and-sonographic-features
#13
Sai-Feng Lin, Shi-Hao Xu, Zuo-Liu Xie
PURPOSE: The purpose of this study was to describe the clinical and sonographic features of calcifying epitheliomas (pilomatrixomas). METHODS: We retrospectively reviewed the clinical data and sonographic appearances of 59 cases of calcifying epitheliomas in 58 patients that were confirmed pathologically. RESULTS: The mean age of the patients was 26 years (range, 5-69 years) and the female-to-male ratio was 1.2. All masses were located in subcutaneous soft tissues...
July 5, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28677375/high-expression-of-cx3c-chemokine-receptor-1-cx3cr1-in-human-carotid-plaques-is-associated-with-vulnerability-of-the-lesions
#14
Marta Masztalewicz, Przemysław Nowacki, Łukasz Szydłowski, Maciej Żukowski, Piotr Gutowski
<i><b>Introduction</b>: In data based on ex vivo studies and animal models, fractalkine is considered an important mediator in the development and destabilization of atherosclerotic plaques. We do not know how it is associated with human carotid plaques morphology. <b>Material and methods</b>: The study included 126 carotid plaques taken from 126 patients who underwent endarterectomy of internal carotid arteries. We assessed the following characteristics: inflammatory infiltration, connective tissue elements, foam cells, lipid core, plaque vascularisation, calcifications, intraplaque haemorrhage, thrombi built into the plaque structure, and mural thrombi...
2017: Folia Neuropathologica
https://www.readbyqxmd.com/read/28673639/management-and-outcome-of-residual-aortic-regurgitation-after-transcatheter-aortic-valve-implantation
#15
Edward Koifman, Romain Didier, Hector Garcia-Garcia, Gaby Weissman, Andrew W Ertel, Sarkis Kiramijyan, Arie Steinvil, Toby Rogers, Nirav Patel, Sandeep Kumar, Arpi Tavil-Shatelyan, Itsik Ben-Dor, Augusto D Pichard, Rebecca Torguson, Jiaxiang Gai, Lowell F Satler, Ron Waksman
We aimed to evaluate the success rates of balloon valvuloplasty post-dilation (BVPD) and a second-valve deployment in reducing residual aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) and its impact on outcome. Residual AR immediately post-TAVI in patients with aortic stenosis is a common condition that adversely affects outcome. Patients who underwent TAVI who had more-than-mild residual AR were managed either with medical therapy, re-intervention with BVPD, or a second valve...
May 31, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28669136/left-ventricular-diverticulum-mimicking-cardiac-tumor
#16
Maciej T Wybraniec, Wojciech Wróbel, Jarosław Myszor, Katarzyna Mizia-Stec
Left ventricular (LV) diverticulum represents a rare and frequently asymptomatic congenital anomaly, which is incidentally discovered during routine transthoracic echocardiography. We present a case of a 66-year-old female patient who was admitted to the cardiology department due to incidental finding of a tumor-like mass associated with the posterior mitral leaflet. Preliminary echocardiographic evaluation revealed a solid structure, suspected of mitral annulus calcification or LV malignancy. However, cardiac contrast-enhanced computed tomography confirmed the presence of LV diverticulum, partially filled with calcified thrombus...
July 2, 2017: Echocardiography
https://www.readbyqxmd.com/read/28666146/intraleaflet-hemorrhages-are-a-common-finding-in-symptomatic-aortic-and-mitral-valves
#17
Olga C G Stam, Mat J A P Daemen, Jan Willem van Rijswijk, Bas A J M de Mol, Allard C van der Wal
INTRODUCTION: Intraleaflet hemorrhage (ILH) has been reported to occur in calcified degenerated aortic valves. At present, no such information is available for mitral valves or for other types of valvular disease. We examined the prevalence, age, and potential source of ILH in a consecutive series of surgically removed aortic and mitral valves, and related the findings to specific types of heart valve pathology. METHODS: A total of 105 aortic (n=85) and mitral (n=20) valves were retrieved from 100 symptomatic patients...
June 17, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28660595/mismatch-between-stiffness-in-elastic-and-muscular-arteries-as-a-predictor-of-vascular-calcification-in-dialysis-patients
#18
Agne Laucyte-Cibulskiene, Modesta Petraviciute, Migle Gudynaite, Liutauras Gumbys, Dileta Valanciene, Kristina Galiauskiene, Ligita Ryliskyte, Laurynas Rimsevicius, Marius Miglinas, Kestutis Strupas
BACKGROUND: Vascular calcification is one of the risk factors for arterial stiffness in patients with chronic kidney disease. We hypothesized that a mismatch between elastic and muscular arteries, represented as pulse wave velocity (PWV) ratio, could depict the extent of vascular calcification in end-stage renal disease. We also aimed to compare the predictive PWV ratio value to other factors possibly related to vascular calcification in dialysis population. METHODS: In this cross-sectional study, in 60 chronic dialysis patients without previous cerebrovascular events, cardiovascular disease and events or clinically evident peripheral artery disease (ankle-brachial index >0...
June 28, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28660279/mineral-depositions-of-calcifying-skin-disorders-are-predominantly-composed-of-carbonate-apatite
#19
Michael Franzen, Elena Müller-More, Janne Cadamuro, Josef Koller, Wolfgang Salmhofer, Iris Wohlmuth-Wieser, Cornelia Kronberger, Hermann Salmhofer
Subcutaneous calcifications can lead to complications, including pain, inflammation, ulceration and immobilization. Studies on the pathophysiology of mineral compositions and effective treatment modalities are limited. We therefore studied 14 patients with subcutaneous calcifications. Mineral material was collected and analysed by Fourier transform infrared spectrometry. Blood analyses were run to evaluate systemic alterations of mineral metabolism. Carbonate apatite (CAP) was found to be the single constituent in the majority of patients (n = 9, 64...
June 29, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28657494/interaction-of-renal-failure-and-dyslipidaemia-in-the-development-of-calcific-aortic-valve-disease-in-rats
#20
Kris Gillis, Bram Roosens, Gezim Bala, Isabel Remory, Sophie Hernot, Philippe Delvenne, Fabienne Mestrez, Steven Droogmans, Bernard Cosyns
OBJECTIVE: Calcific aortic valve disease (CAVD) is currently the most common heart valve disease worldwide and is known to be an active process. Both renal failure and dyslipidaemia are considered to be promoting factors for the development of valvular calcifications. The aim of this study is to prospectively evaluate the respective contribution and interaction of renal failure and dyslipidaemia on CAVD in a rat model, using echocardiography and compared with histology. METHODS AND RESULTS: Sixty-eight male Wistar rats were prospectively divided in eight groups, each fed a different diet to induce renal failure alone and combined with hyperlipidaemia or hypercholesterolemia...
June 28, 2017: Acta Cardiologica
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