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https://www.readbyqxmd.com/read/29143898/the-multidisciplinary-approach-to-localized-pancreatic-adenocarcinoma
#1
REVIEW
Hiral D Parekh, Jason Starr, Thomas J George
Pancreatic adenocarcinoma 2030 (PCa) is predicted to be the second leading cause of cancer death in USA by 2030. To date, attempts at early detection have been unsuccessful. Therapies for resectable PCa include surgery followed by adjuvant chemotherapy with or without radiotherapy. Unfortunately, most patients with PCa present with advanced disease and thus only 20% of patients are potentially resectable upon presentation. Improved surgical techniques along with adjuvant combination chemotherapy have improved outcomes for patients with resectable disease...
November 16, 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/29141716/hansen-s-disease-and-rheumatoid-arthritis-crossover-of-clinical-symptoms-a-case-series-of-18-patients-in-the-united-states
#2
Sarah M Labuda, John S Schieffelin, Jeffrey G Shaffer, Barbara M Stryjewska
Hansen's Disease (HD) is a rare, chronic granulomatous infection of the skin and peripheral nerves caused by the noncultivable organism Mycobacterium leprae. Arthritis is the third most common symptom of HD. Subjects with both confirmed HD on skin biopsy and chronic arthritis were identified at the National Hansen's Disease Program (NHDP). We conducted a series of medical chart reviews and extracted and logged personally deidentified data into a database and carried out descriptive analyses. Eighteen of 261 subjects presented to the NDHP with both HD and chronic arthritis between 2001 and 2015...
October 23, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29140534/divergent-effects-of-oxytocin-on-para-limbic-reactivity-to-emotional-and-neutral-scenes-in-females-with-and-without-borderline-personality-disorder
#3
Alexander Lischke, Sabine C Herpertz, Christoph Berger, Gregor Domes, Matthias Gamer
No abstract text is available yet for this article.
November 1, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/29138960/probable-post-traumatic-stress-disorder-and-self-harming-behaviour-potential-barriers-to-employment
#4
J S Hansen, E Simonsen
The current study screened for post-traumatic stress disorder (PTSD) and self-harming behaviours, often related to borderline personality disorder (BPD), among individuals in a job centre considered unemployable primarily for psychological reasons. Participants (N = 112) filled in questionnaires on PTSD symptoms (n = 62) and self-harming behaviours (n = 59) as part of participating in team-meetings providing the individuals with a return-to-work plan. Differences in demographic variables between individuals with and without valid protocols were small to moderate...
November 14, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/29130718/eating-disorders-during-the-adolescence-personality-characteristics-associated-with-anorexia-and-bulimia-nervosa
#5
Belén Barajas Iglesias, Ignacio Jáuregui Lobera, Isabel Laporta Herrero, Miguel Ángel Santed Germán
INTRODUCTION: Previous studies provide relevant information about the relationship between personality and eating disorders (ED). The involvement of personality factors in the etiology and maintenance of ED indicates the need of emphasizing the study of the adolescent's personality when diagnosed of ED. OBJECTIVES: The aims of this study were to analyze the adolescent's personality profiles that differ significantly in anorexia nervosa (AN) and bulimia nervosa (BN), and to explore the most common profiles and their associations with those subtypes of eating disorders (ED)...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29129552/clinical-characteristics-of-suicidal-behavior-in-an-intensive-care-unit-at-a-university-hospital-in-japan-a-7-year-observational-study
#6
Takashi Takeuchi, Yasuyuki Okumura, Akihito Uezato, Toru Nishikawa
BACKGROUND: Suicidal behavior accounts for at least 40,000 admissions per year to emergency departments in Japan; however, little is known about emergency admissions owing to suicidal behavior in metropolitan areas. Therefore, we examined the clinical characteristics of suicidal behavior using psychosocial assessments performed by experienced psychiatrists in an intensive care unit. METHODS: Participants were 971 patients admitted to a university hospital's intensive care unit for suicidal behavior between July 2006 and June 2013...
November 7, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29120916/impulsivity-in-personality-disorders-current-views-and-future-directions
#7
Catherine McHugh, Sivasankaran Balaratnasingam
PURPOSE OF REVIEW: Impulsivity is considered a trans-diagnostic feature of many mental disorders, yet our understanding of the concept and approaches to measurement have evolved significantly with advances in neuroimaging. This review will provide an overview of impulsivity as it is currently understood, its association with personality disorder and implications for treatment. RECENT FINDINGS: Impulsivity is now considered to involve failure of inhibitory control, either motor or cognitive, and deficits of the reward valuation system...
November 7, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/29120280/self-compassion-mediates-the-relationship-between-mindfulness-and-borderline-personality-disorder-symptoms
#8
Hannah J Scheibner, Anna Daniels, Simon Guendelman, Franca Utz, Felix Bermpohl
Individuals suffering from borderline personality disorder (BPD) experience difficulties with mindfulness. How mindfulness influences BPD symptoms, however, is still unknown. We hypothesized that the relationship between mindfulness and BPD symptoms would be mediated by self-compassion. In study 1, we recruited 29 individuals with BPD and 30 group-matched healthy controls. In study 2, we complemented our results with findings from a larger, nonclinical sample of 89 participants that were recruited during an open-house event at the local university...
November 9, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/29120279/substance-use-in-youth-with-borderline-personality-disorder
#9
Franco Scalzo, Carol A Hulbert, Jennifer K Betts, Sue M Cotton, Andrew M Chanen
Co-occurring substance misuse and borderline personality disorder (BPD) in adults is associated with more severe dysfunction and poorer prognosis than BPD alone. However, it is unknown to what extent substance use in youth with BPD is normative for this age group or pathological. This study compared substance use in 117 help-seeking youth (aged 15-25 years) with their first presentation for treatment of BPD, with an epidemiological general population sample and with healthy age- and gender-matched controls...
November 9, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/29120277/real-world-effectiveness-of-clozapine-for-borderline-personality-disorder-results-from-a-2-year-mirror-image-study
#10
Christopher Rohde, Christoffer Polcwiartek, Christoph U Correll, Jimmi Nielsen
While some second-generation antipsychotics have shown efficacy on patients with borderline personality disorder (BPD), limited data exist regarding the effect of clozapine. Thus, we aimed to investigate the effects of clozapine on naturalistic outcomes in BPD patients with a 2-year mirror-image model. Among 25,916 patients with BPD, 1,107 redeemed ≥ 1 clozapine prescription. Of these, 18,188 were "specific" BPD patients, and 102 redeemed ≥ 1 clozapine prescription. During a mean observation period of 598...
November 9, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/29120194/effect-of-maternal-borderline-personality-disorder-on-adolescents-experience-of-maltreatment-and-adolescent-borderline-features
#11
Gretchen Kurdziel, Stephanie Kors, Jenny Macfie
Borderline personality disorder (BPD) is a severe and chronic mental illness. Self-reported borderline features correlate highly with a diagnosis (affective instability, negative relationships, unstable sense of self, self-harm). Etiological factors of BPD include childhood maltreatment. The current study compared the experience of maltreatment in adolescent offspring of mothers with BPD, who are themselves at risk of developing the disorder, with that of offspring of mothers with no current diagnosis. Participants were 56 adolescents aged 14 to 18 years...
November 9, 2017: Personality Disorders
https://www.readbyqxmd.com/read/29117869/frequency-of-use-of-the-international-classification-of-diseases-icd-10-diagnostic-categories-for-mental-and-behavioural-disorders-across-world-regions
#12
Y Faiad, B Khoury, S Daouk, M Maj, J Keeley, O Gureje, G Reed
AIMS: The study aimed to examine variations in the use of International Classification of Diseases, Tenth Edition (ICD-10) diagnostic categories for mental and behavioural disorders across countries, regions and income levels using data from the online World Psychiatric Association (WPA)-World Health Organization (WHO) Global Survey that examined the attitudes of psychiatrists towards the classification of mental disorders. METHODS: A survey was sent to 46 psychiatric societies which are members of WPA...
November 9, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/29117769/psychophysiological-reactivity-profiles-of-partner-violent-men-with-borderline-or-psychopathic-personality-features-the-role-of-empathy
#13
Nicholas A Armenti, Julia C Babcock
Borderline and psychopathic features have been linked to unique psychophysiological reactivity profiles. Studies have suggested that levels of psychophysiological reactivity for partner-violent men cannot be attributed to personality features alone. This study tested cognitive and affective empathy as moderators of relations between borderline personality, Factor 1 psychopathy, and psychophysiological reactivity using a community sample of 135 male participants and their female partners. Cognitive empathy moderated the relation between borderline personality features and heart rate reactivity...
November 1, 2017: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/29111450/interpersonal-dysfunction-in-borderline-personality-a-decision-neuroscience-perspective
#14
REVIEW
Michael N Hallquist, Nathan T Hall, Alison M Schreiber, Alexandre Y Dombrovski
Borderline personality disorder (BPD) is characterized by disadvantageous decisions that are often expressed in close relationships and associated with intense negative emotions. Although functional neuroimaging studies of BPD have described regions associated with altered social cognition and emotion processing, these correlates do not inform an understanding of how brain activity leads to maladaptive choices. Drawing on recent research, we argue that formal models of decision-making are crucial to elaborating theories of BPD that bridge psychological constructs, behavior, and neural systems...
September 23, 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/29111076/electroconvulsive-therapy-for-depression-with-comorbid-borderline-personality-disorder-or-post-traumatic-stress-disorder-a-matched-retrospective-cohort-study
#15
Tyler S Kaster, David S Goldbloom, Zafiris J Daskalakis, Benoit H Mulsant, Daniel M Blumberger
BACKGROUND: The impact of comorbid borderline personality disorder (BPD) or post-traumatic stress disorder (PTSD) on clinical and cognitive outcomes of electroconvulsive therapy (ECT) in patients with major depressive episodes (MDE) is unknown. OBJECTIVE: Compare clinical response and adverse cognitive effects for MDE patients with comorbid BPD or PTSD to MDE only. METHODS: In a matched retrospective cohort study of 75 patients treated with ECT at an academic psychiatric hospital with DSM-IV MDE and either comorbid BPD, PTSD or both (MDE + BPD/PTSD), 75 MDE patients without BPD or PTSD (MDE-only) were matched...
October 19, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/29106277/dark-and-vulnerable-personality-trait-correlates-of-dimensions-of-criminal-behavior-among-adult-offenders
#16
Bethany G Edwards, Emily Albertson, Edelyn Verona
Given the high-level impact of crime, empirical work is needed to identify personality traits, or overarching factors of personality pathology, that may leave individuals more prone to engage in criminal behaviors. This study empirically tested the distinction between the dark personality and vulnerable dark personality spectra (Miller et al., 2010) in a large offender sample and aimed to test how these personality factors relate to criminal dimensions and individual types of crime. Self-report and public record data verified criminal behaviors for 493 (34...
October 2017: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/29102367/-the-psychiatric-comorbidity-of-anorexia-nervosa-a-comparative-study-in-a-population-of-french-and-greek-anorexic-patients
#17
M Kountza, G Garyfallos, D Ploumpidis, E Varsou, I Gkiouzepas
OBJECTIVE: The current study had two objectives: (1) to access the psychiatric comorbidity in axis I and axis II (according to DSM-IV) of anorexia nervosa in a sample of 60 anorexic patients; (2) to compare the features of the psychiatric comorbidity between the two groups of French and Greek anorexic patients who participated in the study, as well as to compare some psychological and behavioral aspects of their anorectic psychopathology. METHOD: Sixty anorexic patients, thirty French and thirty Greek, aged between 18 and 60 years, referred for evaluation and therapy at the unit of eating disorders at the "Institut national Marcel-Rivière of the MGEN" (hôpital de La Verrière, France) and at the unit of eating disorders of the First Department of Psychiatry of EGINITIO University Psychiatric Hospital in Athens (Greece), were accessed with the Eating Attitudes Test-26 (EAT26), Eating Disorder Inventory (EDI), Symptom Checklist-90-Revised (SCL90R), Mini International Neuropsychiatric Interview, Version 5...
November 1, 2017: L'Encéphale
https://www.readbyqxmd.com/read/29101874/schemas-and-modes-in-borderline-personality-disorder-the-mistrustful-shameful-angry-impulsive-and-unhappy-child
#18
Bo Bach, Joan M Farrell
In this study we investigated how early maladaptive schemas and schema modes uniquely characterize Borderline Personality Disorder (BPD) patients versus comparison groups. BPD patients (n = 101) were systematically matched with personality disordered patients without BPD (n = 101) and healthy controls (n = 101). Differences were investigated using one-way ANOVA and multinomial logistic regression analyses. Results indicated that schemas of Mistrust/Abuse and Defectiveness/Shame along with modes of Angry Child, Impulsive Child, and (low) Happy Child uniquely differentiated BPD patients from patients with other personality disorders...
November 1, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29093819/the-impact-of-borderline-personality-disorder-and-sub-threshold-borderline-personality-disorder-on-the-course-of-self-reported-and-clinician-rated-depression-in-self-harming-adolescents
#19
Ruth-Kari Ramleth, Berit Groholt, Lien M Diep, Fredrik A Walby, Lars Mehlum
Background: Studies on adults suggest that the presence of comorbid depression and Borderline Personality Disorder (BPD) is associated with an elevated risk of self-harming behaviours and that self-harming behaviours, when present, will have higher severity. This comorbidity, furthermore, complicates clinical assessments, which may be an obstacle to early identification and proper intervention. Adolescents who self-harm frequently report high levels of depressive symptoms, but this is often not reflected in the clinicians' assessment...
2017: Borderline Personality Disorder and Emotion Dysregulation
https://www.readbyqxmd.com/read/29083990/always-on-guard-emotion-regulation-in-women-with-borderline-personality-disorder-compared-to-nonpatient-controls-and-patients-with-cluster-c-personality-disorder
#20
Linda van Zutphen, Nicolette Siep, Gitta A Jacob, Gregor Domes, Andreas Sprenger, Bastian Willenborg, Rainer Goebel, Arnoud Arntz
BACKGROUND: Borderline personality disorder (BPD) is characterized by emotion dysregulation; however, it is unclear whether this is restricted to negative emotional stimuli or to what degree this is specific to BPD. We investigated neural correlates of hypothesized increased emotional sensitivity and impaired emotion regulation in patients with BPD. METHODS: During fMRI scanning, patients with BPD, nonpatient controls and patients with cluster-C personality disorder completed an emotion regulation task, including negative, positive and erotic social pictures...
October 30, 2017: Journal of Psychiatry & Neuroscience: JPN
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