Laurence M M Crombag, Kirsten Mooij-Kalverda, Artur Szlubowski, Maciej Gnass, Kurt G Tournoy, Jiayuan Sun, Masahide Oki, Maarten K Ninaber, Daniel P Steinfort, Barton R Jennings, Moishe Liberman, Semra Bilaceroglu, Peter I Bonta, Daniël A Korevaar, Rocco Trisolini, Jouke T Annema
BACKGROUND AND OBJECTIVE: Endosonography with intrathoracic nodal sampling is proposed as the single test with the highest granuloma detection rate in suspected sarcoidosis stage I/II. However, most studies have been performed in limited geographical regions. Studies suggest that oesophageal endosonographic nodal sampling has higher diagnostic yield than endobronchial endosonographic nodal sampling, but a head-to-head comparison of both routes has never been performed. METHODS: Global (14 hospitals, nine countries, four continents) randomized clinical trial was conducted in consecutive patients with suspected sarcoidosis stage I/II presenting between May 2015 and August 2017...
February 2022: Respirology: Official Journal of the Asian Pacific Society of Respirology