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https://www.readbyqxmd.com/read/28936274/a-review-on-wax-printed-microfluidic-paper-based-devices-for-international-health
#1
REVIEW
S Altundemir, A K Uguz, K Ulgen
Paper-based microfluidics has attracted attention for the last ten years due to its advantages such as low sample volume requirement, ease of use, portability, high sensitivity, and no necessity to well-equipped laboratory equipment and well-trained manpower. These characteristics have made paper platforms a promising alternative for a variety of applications such as clinical diagnosis and quantitative analysis of chemical and biological substances. Among the wide range of fabrication methods for microfluidic paper-based analytical devices (μPADs), the wax printing method is suitable for high throughput production and requires only a commercial printer and a heating source to fabricate complex two or three-dimensional structures for multipurpose systems...
July 2017: Biomicrofluidics
https://www.readbyqxmd.com/read/28930347/a-paper-triboelectric-nanogenerator-for-self-powered-electronic-systems
#2
Yanchao Mao, Nan Zhang, Yingjie Tang, Meng Wang, Mingju Chao, Erjun Liang
Paper, as one of the most important inventions of mankind, is still widely used in our daily life. In this study, the paper is explored as a platform for power sources based on the universally known triboelectric friction. A novel paper triboelectric nanogenerator (P-TENG) was successfully developed, which could harvest mechanical energy from ambient sources and generate considerable electrical energy. The maximum power density of the P-TENG reached 53 W m(-2). In addition, the P-TENG possesses a natural advantage of being able to be integrated within a book, and thus can effectively convert mechanical energy from the action of turning book pages into electricity...
September 20, 2017: Nanoscale
https://www.readbyqxmd.com/read/28930183/substituting-sodium-hydrosulfite-with-sodium-metabisulfite-improves-long-term-stability-of-a-distributable-paper-based-test-kit-for-point-of-care-screening-for-sickle-cell-anemia
#3
Kian Torabian, Dalia Lezzar, Nathaniel Z Piety, Alex George, Sergey S Shevkoplyas
Sickle cell anemia (SCA) is a genetic blood disorder that is particularly lethal in early childhood. Universal newborn screening programs and subsequent early treatment are known to drastically reduce under-five SCA mortality. However, in resource-limited settings, cost and infrastructure constraints limit the effectiveness of laboratory-based SCA screening programs. To address this limitation our laboratory previously developed a low-cost, equipment-free, point-of-care, paper-based SCA test. Here, we improved the stability and performance of the test by replacing sodium hydrosulfite (HS), a key reducing agent in the hemoglobin solubility buffer which is not stable in aqueous solutions, with sodium metabisulfite (MS)...
September 20, 2017: Biosensors
https://www.readbyqxmd.com/read/28929878/impact-of-language-barriers-on-access-to-healthcare-for-official-language-minority-francophones-in-canada
#4
Danielle de Moissac, Sarah Bowen
While there is strong international evidence that language barriers present obstacles to healthcare access, quality and safety, little research has been conducted on the experience of official language minorities in Canada. This multiple method research used on-line and paper-based surveys, combined with semi-structured individual interviews to explore the experience with access to care of Francophone minorities living in four Canadian provinces. The majority of Francophones surveyed reported limited access to French language services and described an environment where low importance is given to addressing language barriers within the health system...
July 2017: Healthcare Management Forum
https://www.readbyqxmd.com/read/28923311/colorimetric-detection-of-d-dimer-in-a-paper-based-immunodetection-device
#5
Sónia Ruivo, Ana M Azevedo, Duarte M F Prazeres
A microfluidic paper-based analytical device (μPADs) immunoassay for detection of the blood native biomarker D-dimer is reported. The μPAD is created by wax printing on a single piece of chromatographic paper and combined with an anti-D-dimer capture antibody and conjugates of anti-D-dimer antibody with 40 nm gold nanoparticles. The presence of D-dimer in buffer/simulated plasma samples is successfully reported for concentrations as low as 15 ng D-dimer/mL. Linearity between signal intensity and D-dimer concentration is observed up to 100 ng/mL...
September 15, 2017: Analytical Biochemistry
https://www.readbyqxmd.com/read/28921971/paper-sensor-coated-with-a-poly-carboxybetaine-multiple-dopa-conjugate-via-dip-coating-for-biosensing-in-complex-media
#6
Fang Sun, Kan Wu, Hsiang-Chieh Hung, Peng Zhang, Xinran Che, Joshua Kenyon Smith, Xiaojie Lin, Bowen Li, Priyesh Jain, Qiuming Yu, Shaoyi Jiang
Cellulose paper is an ideal diagnostic platform for low-cost, easily disposable and lightweight implementation, but requires surface modification to achieve detection with high sensitivity and specificity in complex media. In this work, a polymer-catechol conjugate containing a super-hydrophilic nonfouling poly(carboxylbetaine) (pCB) and four surface-binding L-3,4-dihydroxyphenylalanine (DOPA) groups, pCB-(DOPA)4, were applied onto a paper-based sensor surface via a simple "graft-to" immersion process to render the surface with both nonfouling and protein functionalizable properties...
September 18, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28917806/portable-and-low-cost-colorimetric-office-paper-based-device-for-phenacetin-detection-in-seized-cocaine-samples
#7
Gabriela O da Silva, William R de Araujo, Thiago R L C Paixão
An office paper-based colorimetric device is proposed as a portable, rapid, and low-cost sensor for forensic applications aiming to detect phenacetin used as adulterant in illicit seized materials such as cocaine. The proposed method uses white office paper as the substrate and wax printing technology to fabricate the detection zones. Based on the optimum conditions, a linear analytical curve was obtained for phenacetin concentrations ranging from 0 to 64.52µgmL(‒1), and the straight line was in accordance with the following equation: (Magenta percentage color) = 1...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28916329/ecological-extension-of-the-theory-of-evolution-by-natural-selection-from-a-perspective-of-western-and-eastern-holistic-philosophy
#8
REVIEW
Toshiyuki Nakajima
Evolution by natural selection requires the following conditions: (1) a particular selective environment, (2) variation of traits in the population; (3) differential survival/reproduction among types of organisms; and (4) heritable traits. However, the traditional (standard) model does not unclearly explain how and why these conditions are generated or determined. What generates a selective environment? What generates new types? How does a certain type replace, or coexist, with others? In this paper, based on the holistic philosophy in Western and Eastern traditions, I focus on the ecosystem as a higher-level system and generator of conditions that induce the evolution of local populations; I also aim to identify the ecosystem processes that generate those conditions...
September 12, 2017: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/28915385/photoluminescent-lateral-flow-based-on-non-radiative-energy-transfer-for-protein-detection-in-human-serum
#9
Alejandro Zamora-Gálvez, Eden Morales-Narváez, Javier Romero, Arben Merkoçi
A new paper-based lateral flow immunoassay configuration was engineered and investigated. The assay is intended for the detection of a model protein in human serum, that is, human immunoglobulin G, with the aim to demonstrate a virtually universal protein detection platform. Once the sample is added in the strip, the analyte is selectively captured by antibody-decorated silica beads (Ab-SiO2) onto the conjugate pad and the sample flows by capillarity throughout the strip until reaching the test line, where a sandwich-like immunocomplex takes place due to the presence of antibody-functionalized QDs (Ab-QDs) onto the test line...
September 11, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28914301/addressing-the-distribution-of-proteins-spotted-on-%C3%AE-pads
#10
Laura McCann, Tomás E Benavidez, Sarah Holtsclaw, Carlos D Garcia
Adsorption is the most common approach to immobilize biorecognition elements on the surface of paper-based devices. Adsorption is also the route selected to coat the substrate with albumin, therefore minimizing the interaction of other proteins. While similar in nature, the structure of the selected proteins as well as the conditions selected from the immobilization have a significant effect on the amount and distribution of the resulting composites. To illustrate these differences and provide general guidelines to efficiently prepare these devices, this article explores the interaction (adsorption and desorption) of BSA with 3MM chromatography paper...
September 15, 2017: Analyst
https://www.readbyqxmd.com/read/28912562/flexible-supercapacitor-electrodes-based-on-real-metal-like-cellulose-papers
#11
Yongmin Ko, Minseong Kwon, Wan Ki Bae, Byeongyong Lee, Seung Woo Lee, Jinhan Cho
The effective implantation of conductive and charge storage materials into flexible frames has been strongly demanded for the development of flexible supercapacitors. Here, we introduce metallic cellulose paper-based supercapacitor electrodes with excellent energy storage performance by minimizing the contact resistance between neighboring metal and/or metal oxide nanoparticles using an assembly approach, called ligand-mediated layer-by-layer assembly. This approach can convert the insulating paper to the highly porous metallic paper with large surface areas that can function as current collectors and nanoparticle reservoirs for supercapacitor electrodes...
September 14, 2017: Nature Communications
https://www.readbyqxmd.com/read/28912116/reliability-of-an-e-pro-tool-of-eortc-qlq-c30-for-measurement-of-health-related-quality-of-life-in-patients-with-breast-cancer-prospective-randomized-trial
#12
Markus Wallwiener, Lina Matthies, Elisabeth Simoes, Lucia Keilmann, Andreas D Hartkopf, Alexander N Sokolov, Christina B Walter, Nina Sickenberger, Stephanie Wallwiener, Manuel Feisst, Paul Gass, Peter A Fasching, Michael P Lux, Diethelm Wallwiener, Florin-Andrei Taran, Joachim Rom, Andreas Schneeweiss, Joachim Graf, Sara Y Brucker
BACKGROUND: Breast cancer represents the most common malignant disease in women worldwide. As currently systematic palliative treatment only has a limited effect on survival rates, the concept of health-related quality of life (HRQoL) is gaining more and more importance in the therapy setting of metastatic breast cancer. One of the major patient-reported outcomes (PROs) for measuring HRQoL in patients with breast cancer is provided by the European Organization for Research and Treatment of Cancer (EORTC)...
September 14, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28905235/two-new-species-of-xenotarsonemus-acari-tarsonemidae-from-the-atlantic-forest-brazil
#13
A C Lofego, A C C Cavalcante, P R Demite
Two new species, Xenotarsonemus quiriri n. sp. and Xenotarsonemus scorpius n. sp., are described and illustrated in this paper based on specimens collected on Myrtaceae plants in Atlantic Forest areas of the states of Bahia and Santa Catarina, Brazil. A key to identification of Xenotarsonemus species reported from Brazil is provided.
September 13, 2017: Neotropical Entomology
https://www.readbyqxmd.com/read/28903081/ethical-practices-in-community-based-research-in-non-suicidal-self-injury-a-systematic-review
#14
REVIEW
Nupur Singhal, Poornima Bhola
BACKGROUND: The growing interest in community-based research on non-suicidal self-injury (NSSI) reflects the high prevalence rates found among vulnerable adolescents and young adults. A significant concern in research with vulnerable populations, and on sensitive topics, is the development of an ethical framework that protects the needs and rights of the participants while responding to researchers' goals and limitations and the broader clinical and public health concerns. AIM: The aim of the present study was to review the ethical practices followed in community-based research on NSSI...
September 1, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28901134/diagnosis-of-tuberculosis-using-colorimetric-gold-nanoparticles-on-a-paper-based-analytical-device
#15
Tsung-Ting Tsai, Chia-Yu Huang, Chung-An Chen, Shu-Wei Shen, Mei-Chia Wang, Chao-Min Cheng, Chien-Fu Chen
We have developed a colorimetric sensing strategy employing gold nanoparticles and a paper-based analytical platform for the diagnosis of tuberculosis (TB). By utilizing the surface plasmon resonance effect, we were able to monitor changes in the color of a gold nanoparticle colloid based on the effects of single-stranded DNA probe molecules hybridizing with targeted double-stranded TB DNA. The hybridization event changes the surface charge density of the nanoparticles, causing them to aggregate to various degrees, which modifies the color of the solution in a manner that can be readily measured to determine the concentration of the targeted DNA analyte...
September 13, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28898740/transition-from-children-s-to-adult-services-for-young-adults-with-life-limiting-conditions-a-realist-review-of-the-literature
#16
REVIEW
Helen Kerr, Jayne Price, Honor Nicholl, Peter O'Halloran
BACKGROUND: Improvements in care and treatment have led to more young adults with life-limiting conditions living beyond childhood, which means they must make the transition from children's to adult services. This has proved a challenging process for both young adults and service providers, with complex transition interventions interacting in unpredictable ways with local contexts. OBJECTIVES: To explain how intervention processes interact with contextual factors to help transition from children's to adult services for young adults with life-limiting conditions...
June 23, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28894872/lithium-cell-assisted-low-overpotential-li-o2-batteries-by-in-situ-discharge-activation
#17
Jiehua Liu, Wei Chen, Aiming Xing, Xiangfeng Wei, Dongfeng Xue
We report a novel and facile route to improve the catalytic performance of carbon paper-based electrocatalysts, which can be activated by in situ discharging with the assistance of a Li cell. Our results show that the OER potentials were successfully reduced to ∼3.5 V, much lower than the value of 4.5 V for graphite paper, which is the best result recorded amongst the reported carbon-based electrocatalysts.
September 21, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28892693/a-modelling-approach-to-study-the-fouling-of-an-anaerobic-membrane-bioreactor-for-industrial-wastewater-treatment
#18
Amine Charfi, Narumol Thongmak, Boumediene Benyahia, Muhammad Aslam, Jérôme Harmand, Nihel Ben Amar, Geoffroy Lesage, Porntip Sridang, Jeonghwan Kim, Marc Heran
An Anaerobic Membrane BioReactors (AnMBR) model is presented in this paper based on the combination of a simple fouling model and the Anaerobic Model 2b (AM2b) to describe biological and membrane dynamic responses in an AnMBR. In order to enhance the model calibration and validation, Trans-Membrane Pressure (TMP), Total Suspended Solid (TSS), COD, Volatile Fatty Acid (VFA) and methane production were measured. The model shows a satisfactory description of the experimental data with R(2)≈0.9 for TMP data and R(2)≈0...
August 14, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28888493/the-effects-of-smartphone-based-nebulizer-therapy-education-on-parents-knowledge-and-confidence-of-performance-in-caring-for-children-with-respiratory-disease
#19
Jung Min Lee, Shin-Jeong Kim, Hae Young Min
PURPOSE: This study aimed to identify the effects of smartphone-based nebulizer therapy education on the knowledge and confidence of parents while performing care for their children with respiratory disease. DESIGN AND METHODS: This quasi-experimental study employed a pretest-posttest design using a nonequivalent control group. Data were collected from children's parents who had not used nebulizer therapy for their children previously. Both the groups were given nebulizer therapy education using the same content but different learning methods...
September 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28877135/want-correct-percentage-of-tbsa-burned-let-a-layman-do-the-assessment
#20
Ilaria Tocco-Tussardi, Benjamin Presman, Fredrik Huss
Accurate determination of burn size significantly impacts both immediate management and long-term outcome. In the era of evidence-based medicine, the variability in TBSA% assessment shown by traditional methods may prove unacceptable and technology-aided systems become the "accepted standard." The objective of this study was to push this scenario to the limit by investigating the accuracy and consistency of TBSA% estimations using a computer-aided tool. Five Laymen (health care-burn management naïve people) were trained on the handling of the technology-aided assessment tool Burn Case 3D and asked to calculate TBSA% for 18 clinical pictures of burns with different patterns and sizes...
August 31, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
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