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https://www.readbyqxmd.com/read/28816292/-precision-of-three-dimensional-printed-brackets
#1
D Zhang, L C Wang, Y H Zhou, X M Liu, J Li
OBJECTIVE: This study was based on digital orthodontic diagnosis work flow for indirect bonding transfer tray model design and three-dimensional (3D) printing, and the aim of this paper was to inspect the dimensional accuracyof 3D printed brackets, which is the foundation of the follow up work and hoped that will illuminate the clinical application of the digital orthodontics work flow. METHODS: The samples which consisted of 14 cases of patients with malocclusion from Department of Orthodontics Peking University were selected, including 8 cases with tooth extraction and 6 cases without tooth extraction...
August 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28816275/-clinical-application-of-retroperitoneal-laparoscopic-surgery-combined-with-mini-flank-incision-hybrid-surgery-for-partial-nephrectomy-of-complex-renal-tumors
#2
X J Ye, J Liu, A Ablimit, L L Xiong, S J Liu, T Xu, X B Huang
OBJECTIVE: To evaluate the clinical effect and safety of retroperitoneal laparoscopic surgery combined with mini-flank incision "hybrid surgery" for partial nephrectomy of complex renal tumors. METHODS: Between April 2015 and December 2016, the clinical data from 16 patients with complex renal tumors who underwent the "hybrid surgery", including 10 males and 6 females, were retrospectively reviewed. The average age was (50.2±10.7) years, 9 cases were located in the left side and 7 cases in the right side, the mean tumor size was (6...
August 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28813621/improvement-of-an-in-vitro-model-to-assess-delivered-dose-and-particle-size-for-a-vibrating-mesh-nebulizer-during-mechanical-ventilation
#3
Nani Kadrichu, Derek Daniher
BACKGROUND: In an in vitro model of mechanical ventilation with gravity-dependent filter position we observed artificially high delivered doses resulting from liquid droplet collection and precipitation of aerosolized drug. We sequentially modified the model to obtain accurate reproducible measurements of delivered dose and particle size at endotracheal tube exit. METHODS: Stepwise changes in the model included (1) altering the endotracheal tube position to a gravity-independent position, (2) adding fluid traps, (3) humidifying air near the test lung, and (4) simplifying test lung and filters...
August 16, 2017: Journal of Aerosol Medicine and Pulmonary Drug Delivery
https://www.readbyqxmd.com/read/28810788/direct-measurement-of-site-specific-rates-of-reactions-of-h-with-c3h8-i-c4h10-and-n-c4h10
#4
Chia-Chieh Lin, Wei-Yu Chen, Hiroyuki Matsui, Niann-Shiah Wang
We measured the rates of abstraction of a hydrogen atom from specific sites in propane C3H8, 2-methyl propane (i-C4H10), and butane (n-C4H10); the sites are a primary hydrogen of C3H8 and i-C4H10 and a secondary hydrogen of n-C4H10. The excellent reproducibility of conditions of a diaphragm-less shock tube enabled us to conduct comparative measurements of the evolution of H atoms in three mixtures-(i) 0.5 ppm C2H5I + Ar, (ii) 0.5 ppm C2H5I + 50-100 ppm alkane as C3H8 or i-C4H10 or n-C4H10 + Ar, and (iii) the same concentrations of alkane + Ar without C2H5I-in the temperature range 1000-1200 K and at a pressure of 2...
August 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28808988/transoral-resection-of-human-papillomavirus-hpv-positive-squamous-cell-carcinoma-of-the-oropharynx-outcomes-with-and-without-adjuvant-therapy
#5
Ryan S Jackson, Parul Sinha, Joseph Zenga, Dorina Kallogjeri, Jasmina Suko, Eliot Martin, Eric J Moore, Bruce H Haughey
BACKGROUND: With the rise of oropharyngeal squamous cell carcinoma associated with human papillomavirus (HPV), appropriate treatment strategies continue to be tailored toward minimizing treatment while preserving oncologic outcomes. This study aimed to compare the outcomes for those undergoing transoral resection with or without adjuvant therapy for HPV-related oropharyngeal carcinoma. METHODS: A case-match cohort analysis was performed at two institutions on patients with HPV-related oropharyngeal squamous cell carcinoma...
August 14, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28807900/heart-morphogenesis-gene-regulatory-networks-revealed-by-temporal-expression-analysis
#6
Jonathon T Hill, Bradley Demarest, Megan Smith, Bushra Gorsi, H Joseph Yost
During embryogenesis, the heart forms as a linear tube that then undergoes multiple simultaneous morphogenetic events to obtain its mature shape. To understand the gene regulatory networks (GRNs) driving this phase of heart development, during which many congenital heart disease malformations likely arise, we conducted an RNA-seq time course in zebrafish from 30 hpf to 72 hpf and identified 5,861 genes with altered expression. We then clustered the genes by temporal expression pattern, identified transcription factor binding motifs enriched in each cluster, and generated a model GRN for the major gene batteries in heart morphogenesis...
August 14, 2017: Development
https://www.readbyqxmd.com/read/28804889/a-randomised-trial-comparing-real-time-double-lumen-endobronchial-tube-placement-with-the-disposcope-%C3%A2-with-conventional-blind-placement
#7
P T Chen, C K Ting, M Y Lee, H W Cheng, K H Chan, W K Chang
Double-lumen endobronchial tube placement is challenging. This study compared double-lumen tube placement with the Disposcope(®) , a wireless videostylet allowing real-time visualisation, with conventional blind placement. Patients undergoing elective thoracic surgery with normal airways requiring one-lung ventilation were randomly allocated into two groups (27 patients in each group). The Disposcope was used to assist left-sided double-lumen tube placement in one group, and conventional blind placement was performed in the control group...
September 2017: Anaesthesia
https://www.readbyqxmd.com/read/28803962/post-analytical-stability-of-23-common-chemistry-and-immunochemistry-analytes-in-incurred-samples
#8
Betina Klint Nielsen, Tina Frederiksen, Lennart Friis-Hansen, Pia Bükmann Larsen
BACKGROUND: Storage of blood samples after centrifugation, decapping and initial sampling allows ordering of additional blood tests. The pre-analytic stability of biochemistry and immunochemistry analytes has been studied in detail, but little is known about the post-analytical stability in incurred samples. METHODS: We examined the stability of 23 routine analytes on the Dimension Vista® (Siemens Healthineers, Denmark): 42-60 routine samples in lithium-heparin gel tubes (Vacutainer, BD, USA) were centrifuged at 3000×g for 10min...
August 10, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28802403/analytical-evaluation-of-quantiferon-plus-and-quantiferon-gold-in-tube-assays-in-subjects-with-or-without-tuberculosis
#9
E Petruccioli, V Vanini, T Chiacchio, G Cuzzi, D M Cirillo, F Palmieri, G Ippolito, D Goletti
The QuantiFERON-TB Gold Plus (QFT-Plus) represents the new QuantiFERON-TB Gold In-tube (QFT-GIT) to identify latent tuberculosis infection (LTBI). The main differences is the addition of a new tube containing shorter peptides stimulating CD8 T-cells. Aim of this study is to evaluate the accuracy of QFT-Plus compared with QFT-GIT in a cross sectional study of individuals with or without tuberculosis (TB). We enrolled 179 participants: 19 healthy donors, 58 LTBI, 33 cured TB and 69 active TB. QFT-Plus and QFT-GIT were performed...
September 2017: Tuberculosis
https://www.readbyqxmd.com/read/28801889/strategies-of-minimally-invasive-treatment-for-intrahepatic-and-extrahepatic-bile-duct-stones
#10
Zongming Zhang, Zhuo Liu, Limin Liu, Mengmeng Song, Chong Zhang, Hongwei Yu, Baijiang Wan, Mingwen Zhu, Zixu Liu, Hai Deng, Haiming Yuan, Haiyan Yang, Wenping Wei, Yue Zhao
Cholelithiasis is a kind of common and multiple diseases. In recent years, traditional laparotomy has been challenged by a minimally invasive surgery. Through literature review, the therapeutic method, effect, and complications of minimally invasive treatment of intrahepatic and extrahepatic bile duct stones by combining our practical experience were summarized as follows. (1) For intrahepatic bile duct stones, the operation may be selected by laparoscopic liver resection, laparoscopic common bile duct exploration (LCBDE), or percutaneous transhepatic cholangioscopy...
August 12, 2017: Frontiers of Medicine
https://www.readbyqxmd.com/read/28795207/a-prospective-study-of-7-year-experience-using-percutaneous-14-french-pigtail-catheters-for-traumatic-hemothorax-hemopneumothorax-at-a-level-1-trauma-center-size-still-does-not-matter
#11
Zachary M Bauman, Narong Kulvatunyou, Bellal Joseph, Arpana Jain, Randall S Friese, Lynn Gries, Terence O'Keeffe, Andy L Tang, Gary Vercruysse, Peter Rhee
BACKGROUND: The effectiveness of 14-French (14F) pigtail catheters (PCs) compared to 32-40F chest tubes (CTs) in patients with traumatic hemothorax (HTX) and hemopneumothorax (HPTX) is becoming more well known but still lacking. The aim of our study was to analyze our cumulative experience and outcomes with PCs in patients with traumatic HTX/HPTX. We hypothesized that PCs would be as effective as CTs. METHODS: Using our PC database, we analyzed all trauma patients who required chest drainage for HTX/HPTX from 2008 to 2014...
August 9, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28793782/direct-activation-of-nadph-oxidase-2-by-2-deoxyribose-1-phosphate-triggers-nuclear-factor-kappa-b-dependent-angiogenesis
#12
Dina Vara, Joanna M Watt, Tiago M Fortunato, Harry Mellor, Matthew Burgess, Kate Wicks, Kimberly Mace, Shaun Reeksting, Anneke T Lubben, Caroline Pd Wheeler-Jones, Giordano Pula
AIMS: Deoxyribose-1-phosphate (dRP) is a pro-angiogenic paracrine stimulus released by cancer cells, platelets and macrophages and acting on endothelial cells. The objective of this study was to clarify how dRP stimulates angiogenic responses in human endothelial cells. RESULTS: Live cell imaging, electron paramagnetic resonance (EPR), pull-down of dRP-interacting proteins followed by immunoblotting, gene silencing of different NOXs and their regulatory co-subunits by siRNA transfection, and experiments with inhibitors of the sugar transporter GLUT1 were utilized to demonstrate that dRP acts intracellularly by directly activating the endothelial NADPH oxidase 2 (NOX2) complex, but not NOX4...
August 10, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28792750/a-combined-ab-initio-kinetic-modeling-and-shock-tube-study-of-the-thermal-decomposition-of-ethyl-formate
#13
Hongbo Ning, Junjun Wu, Liuhao Ma, Wei Ren, David F Davidson, Ronald K Hanson
The potential energy surfaces (PESs) and reaction rate constants of the unimolecular decomposition of ethyl formate (EF) were investigated using high-precision theoretical methods at the CCSD(T)/CBS(T-Q)//M06-2x/6-311++G(d,p) level of theory. The calculated PESs of EF dissociation and molecular decomposition reactions prove that the intramolecular H-shift to produce formic acid and ethylene is the dominant decomposition pathway. A detailed chemical kinetic mechanism for EF pyrolysis was constructed by incorporating the important reactions of EF and its radicals into an existing mechanism previously developed for small methyl esters...
August 9, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28791811/a-laboratory-study-evaluating-the-ph-of-various-modern-root-canal-filling-materials
#14
Małgorzata Pawińska, Grzegorz Szczurko, Anna Kierklo, Jarosław Sidun
BACKGROUND: Alkaline pH is responsible for antibacterial activity and the stimulation of periapical tissue healing. It neutralizes the acidic environment of inflammatory tissues in the periapical region of the teeth and favors bone repair by activating tissue enzymes. OBJECTIVES: The aim of this study was to evaluate and compare in vitro the pH of 8 root canal filling materials (sealers and points) -AH Plus Jet (AH), Apexit Plus (AP), Endomethasone N (END), Epiphany (EP), GuttaFlow (GF), gutta-percha (G), Resilon (R), Tubliseal (T)...
May 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28790149/evaluation-of-endotracheal-tube-scraping-on-airway-resistance
#15
J Brady Scott, Meagan N Dubosky, David L Vines, Adewunmi S Sulaiman, Kyle R Jendral, Gagan Singh, Ankeet Patel, Carl A Kaplan, David P Gurka, Robert A Balk
BACKGROUND: Spontaneous breathing trials (SBTs) are used to assess the readiness for discontinuation of mechanical ventilation. When airway resistance (Raw) is elevated, the imposed work of breathing can lead to prolongation of mechanical ventilation. Biofilm and mucus build-up within the endotracheal tube (ETT) can increase Raw. Scraping the ETT can remove the biofilm build-up and decrease mechanical Raw. The primary aim of this study was to evaluate the impact of ETT scraping on Raw...
August 8, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28783439/mucorales-spores-induce-a-proinflammatory-cytokine-response-in-human-mononuclear-phagocytes-and-harbor-no-rodlet-hydrophobins
#16
Sebastian Wurster, Vanessa Thielen, Philipp Weis, Paul Walther, Johannes Elias, Ana Maria Waaga-Gasser, Mariola Dragan, Thomas Dandekar, Hermann Einsele, Jürgen Löffler, Andrew J Ullmann
Mucormycoses are life-threatening infections in immunocompromised patients. This study characterizes the response of human mononuclear cells to different Mucorales and Ascomycota. PBMC, monocytes, and monocyte derived dendritic cells (moDCs) from healthy donors were stimulated with resting and germinated stages of Mucorales and Ascomycota. Cytokine response and expression of activation markers were studied. Both inactivated germ tubes and resting spores of Rhizopus arrhizus and other human pathogenic Mucorales species significantly stimulated mRNA synthesis and secretion of proinflammatory cytokines...
August 7, 2017: Virulence
https://www.readbyqxmd.com/read/28782298/transoral-robotic-surgery-for-tonsillar-cancer-addressing-the-contralateral-tonsil
#17
Peter T Dziegielewski, Brian J Boyce, Matthew Old, Theodoros N Teknos, Amit Agrawal, Hafiz Patwa, Enver Ozer
BACKGROUND: The purpose of this study is to determine the incidence and risk factors for bilateral tonsillar cancers treated with transoral robotic surgery (TORS) and to determine the morbidity of the procedure. METHODS: Patients undergoing TORS for known tonsillar cancer were retrospectively reviewed. Perioperative variables and surgical outcomes were analyzed to determine predictive factors for bilateral disease and morbidity rates. RESULTS: Seventy-nine consecutive patients with tonsillar cancers underwent primary TORS radical tonsillectomy...
August 7, 2017: Head & Neck
https://www.readbyqxmd.com/read/28780202/tailor-made-ge-doped-silica-glass-for-clinical-diagnostic-x-ray-dosimetry
#18
Amjad Alyahyawi, T Jupp, M Alkhorayef, D A Bradley
In the modern clinical practice of diagnostic radiology there is a growing demand for radiation dosimetry, it also being recognized that with increasing use of X-ray examinations additional population dose will result, accompanied by an additional albeit low potential for genetic consequences. At the doses typical of diagnostic radiology there is also a low statistical risk for cancer induction; in adhering to best practice, to be also implied is a low but non-negligible potential for deterministic sensitive organ responses, including in regard to the skin and eyes...
July 22, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28774926/complete-measurement-of-helicity-and-its-dynamics-in-vortex-tubes
#19
Martin W Scheeler, Wim M van Rees, Hridesh Kedia, Dustin Kleckner, William T M Irvine
Helicity, a topological measure of the intertwining of vortices in a fluid flow, is a conserved quantity in inviscid fluids but can be dissipated by viscosity in real flows. Despite its relevance across a range of flows, helicity in real fluids remains poorly understood because the entire quantity is challenging to measure. We measured the total helicity of thin-core vortex tubes in water. For helical vortices that are stretched or compressed by a second vortex, we found conservation of total helicity. For an isolated helical vortex, we observed evolution toward and maintenance of a constant helicity state after the dissipation of twist helicity by viscosity...
August 4, 2017: Science
https://www.readbyqxmd.com/read/28771354/theoretical-and-shock-tube-study-of-the-rate-constants-for-hydrogen-abstraction-reactions-of-ethyl-formate
#20
Junjun Wu, Fethi Khaled, Hongbo Ning, Liuhao Ma, Aamir Farooq, Wei Ren
We report a systematic chemical kinetics study of the H-atom abstractions from ethyl formate (EF) by H, O(3P), CH3, OH, and HO2 radicals. The geometry optimization and frequency calculation of all the species were conducted using the M06 method and the cc-pVTZ basis set. The one-dimensional hindered rotor treatment of the reactants and transition states and the intrinsic reaction coordinate analysis were also performed at the M06/cc-pVTZ level of theory. The relative electronic energies were calculated at the CCSD(T)/cc-pVXZ (where X = D, T) level of theory and further extrapolated to the complete basis set limit...
August 3, 2017: Journal of Physical Chemistry. A
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