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https://www.readbyqxmd.com/read/27825353/analysis-of-anti-malarial-resistance-markers-in-pfmdr1-and-pfcrt-across-southeast-asia-in-the-tracking-resistance-to-artemisinin-collaboration
#1
Krongkan Srimuang, Olivo Miotto, Pharath Lim, Rick M Fairhurst, Dominic P Kwiatkowski, Charles J Woodrow, Mallika Imwong
BACKGROUND: Declining anti-malarial efficacy of artemisinin-based combination therapy, and reduced Plasmodium falciparum susceptibility to individual anti-malarials are being documented across an expanding area of Southeast Asia (SEA). Genotypic markers complement phenotypic studies in assessing the efficacy of individual anti-malarials. METHODS: The markers pfmdr1 and pfcrt were genotyped in parasite samples obtained in 2011-2014 at 14 TRAC (Tracking Resistance to Artemisinin Collaboration) sites in mainland Southeast Asia using a combination of PCR and next-generation sequencing methods...
November 8, 2016: Malaria Journal
https://www.readbyqxmd.com/read/27797250/flt3-itd-mutations-in-acute-myeloid-leukemia-patients-in-northeast-thailand
#2
Piyawan Kumsaen, Goonnapa Fucharoen, Chittima Sirijerachai, Su-On Chainansamit, Nittaya Wisanuyothin, Pichayanan Kuwatjanakul, Surapon Wiangnon
The FLT3-ITD mutation is one of the most frequent genetic abnormalities in acute myeloid leukemia (AML) where it is associated with a poor prognosis. The FLT3-ITD mutation could, therefore, be a potential molecular prognostic marker important for risk-stratified treatment options. We amplified the FLT3 gene at exon 14 and 15 in 52 AML patients (aged between 2 months and 74 years) from 4 referral centers (a university hospital and 3 regional hospitals in Northeast Thailand), using a simple PCR method. FLT3-ITD mutations were found in 10 patients (19...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27769299/ex-vivo-piperaquine-resistance-developed-rapidly-in-plasmodium-falciparum-isolates-in-northern-cambodia-compared-to-thailand
#3
Suwanna Chaorattanakawee, Chanthap Lon, Krisada Jongsakul, Jariyanart Gawee, Somethy Sok, Siratchana Sundrakes, Nareth Kong, Chatchadaporn Thamnurak, Soklyda Chann, Sorayut Chattrakarn, Chantida Praditpol, Nillawan Buathong, Nichapat Uthaimongkol, Philip Smith, Narongrid Sirisopana, Rekol Huy, Satharath Prom, Mark M Fukuda, Delia Bethell, Douglas S Walsh, Charlotte Lanteri, David Saunders
BACKGROUND: The recent dramatic decline in dihydroartemisinin-piperaquine (DHA-PPQ) efficacy in northwestern Cambodia has raised concerns about the rapid spread of piperaquine resistance just as DHA-PPQ is being introduced as first-line therapy in neighbouring countries. METHODS: Ex vivo parasite susceptibilities were tracked to determine the rate of progression of DHA, PPQ and mefloquine (MQ) resistance from sentinel sites on the Thai-Cambodian and Thai-Myanmar borders from 2010 to 2015...
October 21, 2016: Malaria Journal
https://www.readbyqxmd.com/read/27738086/peritoneal-dialysis-related-peritonitis-due-to-melioidosis-a-potentially-devastating-condition
#4
Talerngsak Kanjanabuch, Nuttha Lumlertgul, Lachlan J Pearson, Tanittha Chatsuwan, Krit Pongpirul, Asada Leelahavanichkul, Nisa Thongbor, Gunticha Nuntawong, Laksamon Praderm, Pantiwa Wechagama, Surapong Narenpitak, Apinya Wechpradit, Worauma Punya, Guttiga Halue, Phetpailin Naka, Somboon Jeenapongsa, Somchai Eiam-Ong
♦ Background: Melioidosis, an infectious disease caused by Burkholderia pseudomallei, is endemic in Southeast Asia and Northern Australia. Although a wide range of clinical manifestations from this organism are known, peritonitis associated with peritoneal dialysis (PD) has rarely been reported. ♦ Patients and Methods: Peritoneal dialysis patients from all regions in Thailand were eligible for the study if they had peritonitis and either peritoneal fluid or effluent culture positive for B.pseudomallei Patient data obtained included baseline characteristics, laboratory investigations, treatments, and clinical outcomes...
October 13, 2016: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/27701354/a-new-legskate-sinobatis-andamanensis-rajiformes-anacanthobatidae-%C3%A2-from-the-andaman-sea-northeastern-indian-ocean
#5
Peter R Last, Somchai Bussarawit
A new legskate, Sinobatis andamanensis sp. nov. is described from a small collection of specimens taken off Phuket (Thailand) during an exploratory survey of the Andaman Sea. It is the first species of Sinobatis and the only legskate known from the northern Indian Ocean. Sinobatis andamanensis sp. nov. has an especially long and narrowly pointed snout (preorbital length exceeding 23% TL) with an interorbital distance 7-9.5 in snout length (up to 6.7 in other Sinobatis species). Molecular data are unavailable for most members of the genus, but based on morphology it shares with S...
September 14, 2016: Zootaxa
https://www.readbyqxmd.com/read/27696529/outdoor-cultivation-of-dunaliella-salina-ku-11-using-brine-and-saline-lake-water-with-race-way-ponds-in-northeastern-thailand
#6
Zhe Wu, Wipawee Dejtisakdi, Prasart Kermanee, Chunhong Ma, Wallop Arirob, Ramaraj Sathasivam, Niran Juntawong
To evaluate the potential for algal biotechnology to replace traditional agriculture in northeastern Thailand, an open race-way cultivation system was developed to produce biomass and beta-carotene. Dunaliella salina KU 11 isolated from local saline soil was cultured in open race-way tanks using brine and saline lake water. Grown in modified Johnson's medium (with 2-3.5 M NaCl), the algae reached a maximum cell density on the fourth day (1.8×10(6) cells mL(-1) ). Increasing KNO3 and NaHCO3 from 0.5 and 0.043 g L(-1) to 1 and 2...
October 3, 2016: Biotechnology and Applied Biochemistry
https://www.readbyqxmd.com/read/27685448/health-related-quality-of-life-and-survival-of-cholangiocarcinoma-patients-in-northeastern-region-of-thailand
#7
Somkiattiyos Woradet, Nopparat Songserm, Supannee Promthet, Donald Maxwell Parkin
In northeast Thailand, cholangiocarcinoma (CCA) is a major cause of mortality. Patients with CCA have a poor prognosis and short-term survival. The purpose of this study was to investigate the association between health-related quality of life (HRQOL) and survival time, and to explore whether change in HRQOL score is related to survival among CCA patients. The study was performed between February 2011 and January 2012, and included 171 patients with newly diagnosed CCA from 5 tertiary hospitals in four provinces of northeast Thailand...
2016: PloS One
https://www.readbyqxmd.com/read/27668750/analyses-of-the-distribution-patterns-of-burkholderia-pseudomallei-and-associated-phages-in-soil-samples-in-thailand-suggest-that-phage-presence-reduces-the-frequency-of-bacterial-isolation
#8
Patoo Withatanung, Narisara Chantratita, Veerachat Muangsombut, Natnaree Saiprom, Ganjana Lertmemongkolchai, Jochen Klumpp, Martha R J Clokie, Edouard E Galyov, Sunee Korbsrisate
BACKGROUND: Burkholderia pseudomallei is a soil saprophytic bacterium that causes melioidosis. The infection occurs through cutaneous inoculation, inhalation or ingestion. Bacteriophages (phages) in the same ecosystem may significantly impact the biology of this bacterium in the environment, and in their culturability in the laboratory. METHODS/PRINCIPAL FINDINGS: The soil samples were analysed for the presence of bacteria using culture methods, and for phages using plaque assays on B...
September 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27615907/revision-of-the-oriental-subfamily-heteropteryginae-kirby-1896-with-a-re-arrangement-of-the-family-heteropterygidae-and-the-descriptions-of-five-new-species-of-haaniella-kirby-1904-%C3%A2-phasmatodea-areolatae-heteropterygidae
#9
Frank H Hennemann, Oskar V Conle, Paul D Brock, Francis Seow-Choen
The areolate Oriental family Heteropterygidae Kirby, 1893 is critically reviewed and the results of the present study contradict the arrangement suggested by Zompro (2004), but in most aspects agree with a molecular study presented by Whiting et al (2003) and a phylogenetic study presented by Bradler (2009). The family is critically discussed and new hypotheses are presented for the phylogeny and intra-familiar relationships, placing the subfamily Dataminae Rehn & Rehn, 1939 as the basalmost clade of Heteropterygidae...
2016: Zootaxa
https://www.readbyqxmd.com/read/27573633/scrub-typhus-in-northeastern-thailand-eschar-distribution-abnormal-electrocardiographic-findings-and-predictors-of-fatal-outcome
#10
Wilawan Thipmontree, Wiwit Tantibhedhyangkul, Saowaluk Silpasakorn, Ekkarat Wongsawat, Duangdao Waywa, Yupin Suputtamongkol
Scrub typhus is endemic in Thailand. Of the 495 patients with acute undifferentiated fever studied in Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand, from June 1, 2011, to December 31, 2012, 146 patients (29.5%) had confirmed scrub typhus. The majority of cases were male, farmers, with the mean (±standard deviation) age of 54.1 ± 15.2 years. A total of 59 patients (40.4%) had eschar lesion. The commonest sites for an eschar in male patients were the perineum, inguinal, and buttock area; whereas in females, it was the head and neck area...
October 5, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27432370/factors-associated-with-healthy-aging-among-older-persons-in-northeastern-thailand
#11
Pornpun Manasatchakun, Pleumjit Chotiga, Jacek Hochwälder, Åsa Roxberg, Maria Sandborgh, Margareta Asp
The aim of this study was to describe factors associated with perceived health and healthy aging among older people in northeastern Thailand. Thailand's aging population is growing and facing an increasing old-age dependency ratio. Northeastern Thailand, known as Isan, is a region in which the number of older residents is projected to grow rapidly. Older people in this region are likely to confront great threats to their health and well-being. These issues require appropriate attention and actions to promote healthy aging...
December 2016: Journal of Cross-cultural Gerontology
https://www.readbyqxmd.com/read/27395859/a-checklist-of-recent-non-marine-ostracods-crustacea-ostracoda-%C3%A2-from-thailand-including-descriptions-of-two-new-species
#12
Sukonthip Savatenalinton, Maitree Suttajit
A checklist covering a total of 67 Recent non-marine ostracod species from Thailand, belonging to 33 genera and seven families (Cyprididae, Candonidae, Ilyocyprididae, Notodromadidae, Darwinulidae, Limnocytheridae, Loxoconchidae), is presented. Twenty-five of these are considered endemic to the Oriental region, 17 of which are Thai endemics. Two        species (Hemicypris exiqua Broodbakker, 1983, and Notodromas sinensis Neal & Zhao, 1991) are new records for the Oriental region, and four species (Cypretta seurati Gauthier, 1929, Chrissia ceylonica (Daday, 1898), Chrissia formosa (Klie, 1938), and Dolerocypris fasciata (O...
2016: Zootaxa
https://www.readbyqxmd.com/read/27356720/opisthorchis-viverrini-infection-among-people-in-the-border-areas-of-three-provinces-northeast-of-thailand
#13
Soraya J Kaewpitoon, Ratana Rujirakul, Rujirakul Wakkuwattapong, Likit Matrakool, Taweesak Tongtawee, Sukij Panpimanmas, Prasit Pengsaa, Darawan Jomkoa, Apinya Joosiri, Natthawut Kaewpitoon
Opisthorchis viverrini is still a serious problem in Northeastern and Northern Thailand. Active surveillance is required to determine updated data for further prevention and control planning. Therefore, this study aimed to examine the prevalence and risk factors for O. viverrini in three provinces, Northeastern Thailand. A cross- sectional survey was conducted during October 2015 to March 2016 at Kaeng Sanam Nang district of Nakhon Ratchasima province, Waeng Noi district of Khon Kaen province, and Khon Sawan district of Chaiyaphum province, Thailand...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27302016/a-nationwide-survey-of-pathogenic-leptospires-in-urine-of-cattle-and-buffaloes-by-loop-mediated-isothermal-amplification-lamp-method-in-thailand-2011-2013
#14
Duangjai Suwancharoen, Supaluck Limlertvatee, Philaiphon Chetiyawan, Phichet Tongpan, Nongluck Sangkaew, Yaowarat Sawaddee, Kanya Inthakan, Anuwat Wiratsudakul
Leptospirosis is a worldwide distributed zoonosis which has long been endemic in Thailand. Cattle and buffaloes are important livestock species that live in close contact with humans, especially in rural areas. These animals may, therefore, act as long-term carriers of leptospirosis for humans and other livestock species. The present study employed loop-mediated isothermal amplification (LAMP) method to detect pathogenic leptospiral 16S rDNA in the urine of cattle and buffaloes for assessing associations between uroprevalence and species, sex, age and spatial distribution...
June 13, 2016: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/27271702/a-combination-of-liver-fluke-infection-and-traditional-northeastern-thai-foods-associated-with-cholangiocarcinoma-development
#15
Pranee Sriraj, Thidarut Boonmars, Ratchadawan Aukkanimart, Jiraporn Songsri, Panupan Sripan, Panaratana Ratanasuwan, Sirintip Boonjaraspinyo, Nadchanan Wongchalee, Porntip Laummaunwai
Opisthorchis viverrini infection is one of the risk factors for cholangiocarcinoma (CCA) in northeast Thailand, a region with one of the highest reported incidence rates of CCA. The traditional practice of eating raw fish, repeated exposure to liver flukes, and consumption of nitrosamine-contaminated food are major risk factors for CCA. So far, there have been no reports about which northeastern traditional dishes may be involved in CCA development. The present study, thus, investigated the effects of traditional foods...
October 2016: Parasitology Research
https://www.readbyqxmd.com/read/27244970/epidemiological-patterns-of-transport-accident-mortality-in-thailand
#16
Nuntaporn Klinjun, Apiradee Lim, Kanitta Bundhamcharoen
This study aimed to explore patterns of transport accident mortality in Thailand between 2004 and 2009. Vital Registration (VR) data were obtained from the Thai Ministry of Public Health and corrected causes of death were derived from Verbal Autopsy (VA) data collected in 2005. A total of 136,164 deaths were analyzed. Poisson regression was used for identifying mortality patterns with respect to gender-age groups and province-year groups. Regression coefficients were used to classify mortality trends for the 76 provinces...
March 2016: Southeast Asian Journal of Tropical Medicine and Public Health
https://www.readbyqxmd.com/read/27221919/surveillance-of-populations-at-risk-of-cholangiocarcinoma-development-in-rural-communities-of-thailand-using-the-korat-cca-verbal-screening-test
#17
Soraya J Kaewpitoon, Ratana Rujirakul, Ryan A Loyd, Sukij Panpimanmas, Likit Matrakool, Taweesak Tongtawee, Porntip Kompor, Jun Norkaew, Wasugree Chavengkun, Parichart Wakkhuwattapong, Jirawoot Kujapun, Sukanya Ponphimai, Tanida Phatisena, Thawatchai Eaksunti, Poowadol Polsripradist, Apinya Joosiri, Inchat Sukkasam, Natnapa Padchasuwan, Natthawut Kaewpitoon
Cholangiocarcinoma (CCA) is a serious problem in Thailand, particularly in the northeastern region. Active surveillance in rural communities with an appropriat low-cost screening tool is required to facilitate early detection. Therefore, this study aimed to investigate the population at risk of CCA in Bua Yai district, Nakhon Ratchasima province, Northeastern Thailand using the Korat-CCA verbal screening test (KCVST) during June to October 2015. Reliability of KCVST demonstrated a Cronbach alpha coefficient=0...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27212569/test-of-sex-estimation-equations-on-carpal-bones-in-a-northeastern-thai-population
#18
S Laowatthanaphong, S Das, M Phatsara, P Tuamsuk, P Mahakkanukrauh
BACKGROUND: Sex assessment is an essential step in person identification, both in forensic and anthropological contexts. Many parts of skeletal remains such as skull, pelvis and long bones have been proven to be useful in determining sex. However, literature has shown that short bones such as carpal bones are also sexually dimorphic. In the last few years, there was an unpublished study using lunate, scaphoid and hamate from bone collection in Northern Thailand to create 6 discriminant equations to assess sex...
March 2016: La Clinica Terapeutica
https://www.readbyqxmd.com/read/27115772/the-comparative-double-blind-clinical-study-in-antihelmintic-efficacy-between-thai-traditional-herbal-formulae-and-mebendazole
#19
Buavaroon Srichaikul, Supachai Samappito, Surapote Wongyai, Gordon Bakker
This study was carried out in Mahasarakham Primary Healthcare Centre, Mahasarakham province in the area of Northeastern of Thailand. The experiment was randomized controlled trial in the clinical study to examine the efficacy of Thai Traditional Herbal Formula (TTHF) in the treatment of antihelmintic activity of mixed worm infections in human. The 2 experimental groups consisted of 10 patients, and 5 patients for control group with inclusion and exclusion criteria, who were screened by the selection of mixed worm infection symptom samples...
July 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/27099682/the-effects-of-light-temperature-and-nutrition-on-growth-and-pigment-accumulation-of-three-dunaliella-salina-strains-isolated-from-saline-soil
#20
Zhe Wu, Promchup Duangmanee, Pu Zhao, Niran Juntawong, Chunhong Ma
BACKGROUND: Developing algal industries in saline-alkali areas is necessary. However, suitable strains and optimal production conditions must be studied before widespread commercial use. OBJECTIVES: The effects of light, temperature, KNO3, and CO(NH2)2 on beta-carotene and biomass accumulation were compared and evaluated in order to provide scientific guidance for commercial algal production in northeastern Thailand. MATERIALS AND METHODS: An orthogonal design was used for evaluating optimal conditions for the algal production of three candidate Dunaliella salina strains (KU XI, KU 10 and KU 31) which were isolated from saline soils and cultured in the column photobioreactor...
January 2016: Jundishapur Journal of Microbiology
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