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https://www.readbyqxmd.com/read/29025415/genetic-evidence-of-multiple-invasions-and-a-small-number-of-founders-of-asian-palmyra-palm-borassus-flabellifer-in-thailand
#1
Kwanjai Pipatchartlearnwong, Akarapong Swatdipong, Supachai Vuttipongchaikij, Somsak Apisitwanich
BACKGROUND: Borassus flabellifer or Asian Palmyra palm is an important crop for local economies in the South and Southeast Asia for its fruit and palm sugar production. Archeological and historical evidence indicated the presence of this species in Southeast Asia dating back at least 1500 years. B. flabellifer is believed to be originated in Africa, spread to South Asia and introduced into Southeast Asia through commercial routes and dissemination of cultures, however, the nature of its invasion and settlement in Thailand is unclear...
October 12, 2017: BMC Genetics
https://www.readbyqxmd.com/read/28931405/evaluating-a-preoperative-protocol-that-includes-magnetic-resonance-imaging-for-lymph-node-metastasis-in-the-cholangiocarcinoma-screening-and-care-program-cascap-in-thailand
#2
Metha Songthamwat, Nittaya Chamadol, Narong Khuntikeo, Jadsada Thinkhamrop, Supinda Koonmee, Nathaphop Chaichaya, Jeffrey Bethony, Bandit Thinkhamrop
BACKGROUND: Treatment planning especially liver resection in cholangiocarcinoma (CCA) depends on the extension of tumor and lymph node metastasis which is included as a key criterion for operability. Magnetic resonance imaging (MRI) offers a rapid and powerful tool for the detection of lymph node metastasis (LNM) and in the current manuscript is assessed as a critical tool in the preoperative protocol for liver resection for treatment of CCA. However, the accuracy of MRI to detect LNM from CCA had yet to be comprehensively evaluated...
September 20, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28923008/an-eleven-year-retrospective-hospital-based-study-of-epidemiological-data-regarding-human-strongyloidiasis-in-northeast-thailand
#3
Thidarat K Prasongdee, Pokkamol Laoraksawong, Wanida Kanarkard, Ratthaphol Kraiklang, Kraisit Sathapornworachai, Sureeporn Naonongwai, Porntip Laummaunwai, Oranuch Sanpool, Pewpan M Intapan, Wanchai Maleewong
BACKGROUND: Human strongyloidiasis is a chronic and persistent gastrointestinal disease caused by infection with soil-transmitted helminths of the genus Strongyloides. The aim of this research was to obtain diagnostic prevalence regarding strongyloidiasis in northeast Thailand through a hospital-based study. METHODS: Patients' demographic data and the results of stool examinations conducted using the formalin ethyl acetate concentration technique were collected from the parasitology laboratory records at Srinagarind Hospital in Khon Kaen, Thailand...
September 18, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28817104/national-and-subnational-population-based-incidence-of-cancer-in-thailand-assessing-cancers-with-the-highest-burdens
#4
Shama Virani, Surichai Bilheem, Wasan Chansaard, Imjai Chitapanarux, Karnchana Daoprasert, Somsak Khuanchana, Atit Leklob, Donsuk Pongnikorn, Laura S Rozek, Surattaya Siriarechakul, Krittika Suwanrungruang, Sukit Tassanasunthornwong, Patravoot Vatanasapt, Hutcha Sriplung
In Thailand, five cancer types-breast, cervical, colorectal, liver and lung cancer-contribute to over half of the cancer burden. The magnitude of these cancers must be quantified over time to assess previous health policies and highlight future trajectories for targeted prevention efforts. We provide a comprehensive assessment of these five cancers nationally and subnationally, with trend analysis, projections, and number of cases expected for the year 2025 using cancer registry data. We found that breast (average annual percent change (AAPC): 3...
August 17, 2017: Cancers
https://www.readbyqxmd.com/read/28809071/physicians-communication-of-risks-from-non-steroidal-anti-inflammatory-drugs-and-attitude-towards-providing-adverse-drug-reaction-information-to-patients
#5
Pacharaporn Phueanpinit, Juraporn Pongwecharak, Sermsak Sumanont, Janet Krska, Narumol Jarernsiripornkul
RATIONALE, AIMS, AND OBJECTIVES: Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently prescribed for orthopaedic conditions, therefore this study aimed to explore orthopaedic physicians' perceptions of their role in NSAID-risk communication, their attitudes towards the necessity of informing patients about adverse drug reactions (ADR), and factors associated with these. METHODS: Self-administered questionnaires were mailed to all 206 orthopaedic physicians working at hospitals in Northeastern Thailand...
August 15, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28759343/epidemiologic-study-of-major-complications-in-adolescent-and-adult-patients-with-thalassemia-in-northeastern-thailand-the-e-saan-study-phase-i
#6
Nattiya Teawtrakul, Arunee Jetsrisuparb, Saranya Pongudom, Chittima Sirijerachai, Kanchana Chansung, Chinadol Wanitpongpun, Supan Fucharoen
INTRODUCTION: Thalassemia-related complications are one of the main factors that increase morbidity and mortality in aging patients with thalassemia. This study was aimed to report the prevalence and clinical risk factors for the complications in thalassemia. METHODS: A multi-center prospective cohort study was conducted in patients with thalassemia aged ≥10 years old. Thalassemia-related complications were heart failure, pulmonary hypertension, extramedullary hematopoiesis, endocrine disorders, infections, thrombosis and leg ulcers...
July 31, 2017: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/28751237/a-large-modern-southeast-asian-human-skeletal-collection-from-thailand
#7
Nawaporn Techataweewan, Panya Tuamsuk, Yanyong Toomsan, Worawut Woraputtaporn, Parichat Prachaney, Nancy Tayles
The Khon Kaen University Human Skeleton Research Centre has a large human collection consisting of 745 modern northeastern Thai (Isan) skeletons derived from bodies bequeathed to the Department of Anatomy during the period 1979-2014. The aim of this paper is to document the collection and address the question of whether the collection may be representative of local Isan people, or populations of the wider region of mainland Southeast Asia. This will determine its value as a reference collection for forensic anthropology in particular but also for all other fields of research about human skeletal biology...
September 2017: Forensic Science International
https://www.readbyqxmd.com/read/28749110/haplotype-analysis-of-mdr1-and-risk-for-cervical-cancer-in-northeastern-thailand
#8
Sophida Phuthong, Wannapa Settheetham-Ishida, Sitakan Natphopsuk, Dariwan Settheetham, Takafumi Ishida
Objective: The aim of this study was to investigate the association between genotype and haplotype of MDR1 (C1236T, G2677T/A and C3435T) and the risk for cervical cancer in Northeastern Thai women. Methods: An age-matched case-control study involving squamous cell cervical cancer (SCCA) patients (n=204) and healthy controls (n=204) was enrolled for MDR1 genotyping by real-time PCR method. Results: The genotype distribution of MDR1 in both patients and controls was not significantly different (p>0.05). The haplotype analysis showed that T-T-T was the most common haplotype in this population...
July 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28743278/status-of-insecticide-resistance-in-anopheles-mosquitoes-in-ubon-ratchathani-province-northeastern-thailand
#9
Anchana Sumarnrote, Hans J Overgaard, Nattapol Marasri, Bénédicte Fustec, Kanutcharee Thanispong, Theeraphap Chareonviriyaphap, Vincent Corbel
BACKGROUND: Malaria is common in hilly, forested areas along national borders in Southeast Asia. Insecticide resistance in malaria vectors has been detected in a few countries in the Greater Mekong sub-region (GMS), representing a threat to malaria control and prevention. This study aims to determine the insecticide resistance status of Anopheles mosquitoes in Ubon Ratchathani province, northeastern Thailand, where increasing number of malaria cases were reported recently. METHODS: Mosquitoes were collected in 2013-2015 using human landing and cattle bait collections in six sites during both the rainy and dry seasons...
July 25, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28699535/protein-kinases-as-targets-for-opisthorchis-viverrini-associated-cholangiocarcinoma-therapy
#10
Watcharin Loilome, Hasaya Dokduang
Protein kinases are enzymes that catalyze the transfer of phosphate from ATP to the serine/threonine or tyrosine residues of target molecules. These are key important mediators in a signaling cascade involved in several biological processes. Dysregulation of their activity has been found in various tumors. From our increased understanding of kinase structure and activation mechanisms there emerged new strategies for targeting kinase in cancer treatment. Nowadays, kinase specific inhibitors are developed and widely used for clinical cancer treatment...
July 10, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28679748/evolution-of-the-staphylococcus-argenteus-st2250-clone-in-northeastern-thailand-is-linked-with-the-acquisition-of-livestock-associated-staphylococcal-genes
#11
Danesh Moradigaravand, Dorota Jamrozy, Rafal Mostowy, Annaliesa Anderson, Emma K Nickerson, Janjira Thaipadungpanit, Vanaporn Wuthiekanun, Direk Limmathurotsakul, Sarunporn Tandhavanant, Chanthiwa Wikraiphat, Gumphol Wongsuvan, Nittaya Teerawattanasook, Yaowaruk Jutrakul, Nuttiya Srisurat, Prajuab Chaimanee, T Eoin West, Beth Blane, Julian Parkhill, Narisara Chantratita, Sharon J Peacock
Staphylococcus argenteus is a newly named species previously described as a divergent lineage of Staphylococcus aureus that has recently been shown to have a global distribution. Despite growing evidence of the clinical importance of this species, knowledge about its population epidemiology and genomic architecture is limited. We used whole-genome sequencing to evaluate and compare S. aureus (n = 251) and S. argenteus (n = 68) isolates from adults with staphylococcal sepsis at several hospitals in northeastern Thailand between 2006 and 2013...
July 5, 2017: MBio
https://www.readbyqxmd.com/read/28646835/association-between-blood-cholinesterase-activity-organophosphate-pesticide-residues-on-hands-and-health-effects-among-chili-farmers-in-ubon-ratchathani-province-northeastern-thailand
#12
Thitirat Nganchamung, Mark G Robson, Wattasit Siriwong
Background: Use of pesticides has been documented to lead to several adverse health effects. Farmers are likely to be exposed to pesticides through dermal exposure as a result of mixing, loading, and spraying. Organophosphate pesticides (OPs) are widely used in most of the agricultural areas throughout Thailand. OPs are cholinesterase inhibitors and blood cholinesterase activity is used as a biomarker of OP effects. Objective: This study aims to determine the association between blood cholinesterase activity and organophosphate pesticide residues on chili farmer’s hands and their adverse health effects...
2017: Roczniki Państwowego Zakładu Higieny
https://www.readbyqxmd.com/read/28440978/methylation-status-of-p16ink4a-in-human-papillomavirus-associated-cancer-of-oral-cavity-and-oropharynx-in-northeastern-thailand
#13
Piyawut Swangphon, Chamsai Pientong, Ati Burassakarn, Patravoot Vatanasapt, Pilaiwan Kleebkaow, Natcha Patarapadungkit, Thanabut Treebupachatsakul, Supannee Promthet, Bunkerd Kongyingyoes, Tipaya Ekalaksananan
Background: Over-expression of p16INK4a protein is a biomarker for human papillomavirus (HPV)-associated cervical cancer. However, absence of p16INK4a protein expression in HPV-associated cancer of the oral cavity and oropharynx has been reported. Among a number of possible reasons for this is methylation, which is frequently noted in the promoter region of p16INK4a and is associated with silencing of the gene and disease severity. Methods: We investigated the relationships between p16INK4a protein expression, HPV infection and methylation status of the p16INK4a promoter in cancers of the oral cavity and oropharynx...
March 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28431957/genetic-study-of-kir-and-hla-ligands-in-235-individuals-from-northeastern-thailand
#14
Suwit Chaisri, Chanvit Leelayuwat, Amornrat Romphruk
The diversity of 17 KIR and HLA ligands (HLA-C1, C2, Bw4, A11) were investigated in two hundred and thirty-five unrelated healthy donors in Northeastern Thais (NETs) by the polymerase chain reaction with sequence-specific primer (PCR-SSP) method. The Hardy-Weinberg Equilibrium (HWE) was used to verify genotyping method for dimorphic KIR and HLA. They were in HWE (p>0.05). KIR and HLA ligands frequencies, genotypes, haplotypes and linkage disequilibrium (LD) were presented. The genetic data are available in allele Frequencies Net Database...
April 18, 2017: Human Immunology
https://www.readbyqxmd.com/read/28412524/antimicrobial-resistance-and-genetic-diversity-of-the-sxt-element-in-vibrio-cholerae-from-clinical-and-environmental-water-samples-in-northeastern-thailand
#15
Wanida Mala, Kiatichai Faksri, Kittipan Samerpitak, Umaporn Yordpratum, Wanlop Kaewkes, Unchalee Tattawasart, Chariya Chomvarin
Multidrug resistance in V. cholerae has been increasing around the world including northeastern Thailand. The aquatic environment is a reservoir of V. cholerae and might be an important source of resistant strains. The aims of this study were to investigate the phylogenetic relationships of intSXT gene sequences from 31 clinical and 14 environmental V. cholerae O1 and non-O1/non-O139 isolates and 11 sequences amplified directly from environmental water samples. We also amplified class 1 integrons, the SXT elements (targeting the intSXT gene) and antimicrobial resistance genes directly from water samples...
April 13, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28372560/fish-sharing-as-a-risk-factor-for-opisthorchis-viverrini-infection-evidence-from-two-villages-in-north-eastern-thailand
#16
Parichat Saenna, Cameron Hurst, Pierre Echaubard, Bruce A Wilcox, Banchob Sripa
BACKGROUND: Foodborne trematodiasis (FBT) is a significant global health problem, with the liver flukes Opisthorchis viverrini, O. felineus, and Clonorchis sinensis contributing to half of the global burden of FBT. North-eastern Thailand where O. viverrini is endemic and un-cooked fish dishes remain an integral part of the food culture has the highest reported incidence of opisthorchiasis, including associated cholangiocarcinoma. Both food sharing and eating practices are potentially important factors in FTB, suggesting an important role for the social ecology of disease transmission in these rural communities...
April 4, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28353659/a-pharmacological-examination-of-the-cardiovascular-effects-of-malayan-krait-bungarus-candidus-venoms
#17
Janeyuth Chaisakul, Muhamad Rusdi Ahmad Rusmili, Wayne C Hodgson, Panadda Hatthachote, Kijja Suwan, Anjaree Inchan, Lawan Chanhome, Iekhsan Othman, Krongkarn Chootip
Cardiovascular effects (e.g., tachycardia, hypo- and/or hypertension) are often clinical outcomes of snake envenoming. Malayan krait (Bungarus candidus) envenoming has been reported to cause cardiovascular effects that may be related to abnormalities in parasympathetic activity. However, the exact mechanism for this effect has yet to be determined. In the present study, we investigated the in vivo and in vitro cardiovascular effects of B. candidus venoms from Southern (BC-S) and Northeastern (BC-NE) Thailand...
March 29, 2017: Toxins
https://www.readbyqxmd.com/read/28347653/cytochrome-c-oxidase-subunit-i-haplotype-diversity-of-angiostrongylus-cantonensis-nematoda-angiostrongylidae
#18
Praphathip Eamsobhana, Sze-Looi Song, Hoi-Sen Yong, Anchana Prasartvit, Sudarat Boonyong, Anchalee Tungtrongchitr
The rat lungworm Angiostrongylus cantonensis is a food-borne zoonotic parasite of public health importance worldwide. It is the primary etiologic agent of eosinophilic meningitis and eosinophilic meningoencephalitis in humans in many countries. It is highly endemic in Thailand especially in the northeast region. In this study, A. cantonensis adult worms recovered from the lungs of wild rats in different geographical regions/provinces in Thailand were used to determine their haplotype by means of the mitochondrial partial cytochrome c oxidase subunit I (COI) gene sequence...
March 27, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28345841/carcinogenic-liver-fluke-and-others-contaminated-in-pickled-fish-of-northeastern-thailand
#19
Ratchadawan Aukkanimart, Thidarut Boonmars, Pranee Sriraj, Panupan Sripan, Jiraporn Songsri, Panaratana Ratanasuwan, Porntip Laummaunwai, Apiporn Suwanantrai, Surasit Aunpromma, Sukhonthip Khueangchaingkhwang, Benjamabhorn Pumhirunroj, Atchara Artchayasawat, Narong Khuntikeo, Watcharin Loilome, Nisana Namwat, Puangrat Yongvanit, Sirintip Boonjaraspinyo
Twenty provinces in northeastern Thailand were investigated for fluke metacercariae contamination in pickled fish, or pla-som, during January –June 2016. A total of 129 pickled fish shops were randomly chosen. Samples were digested with acid-pepsin and those found to be infected with metacercariae were fed to hamsters to test for metacercariae infectivity. The results demonstrated that only 20.2% of the pla-som samples were infected with fluke metacercariae (mc), at various levels (1 to 268 mc/kg). All recovered fluke metacercariae were inactive, degenerated and could not develop to adults in the animal model...
February 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28339543/climatic-factors-and-prevalence-of-campylobacter-in-commercial-broiler-flocks-in-thailand
#20
S Prachantasena, P Charununtakorn, S Muangnoicharoen, L Hankla, N Techawal, P Chaveerach, P Tuitemwong, N Chokesajjawatee, N Williams, T Humphrey, T Luangtongkum
Campylobacter are bacteria associated with human foodborne disease worldwide. Poultry and poultry products are generally considered as a main source of these organisms. Compared to temperate zones, baseline information on Campylobacter in tropical regions is limited. Thus, the objectives of the present study were 1) to determine the prevalence of Campylobacter in Thai broiler flocks and 2) to investigate the association between climatic factors (i.e., rainfall, ambient temperature, and relative humidity) and Campylobacter colonization status of broiler flocks in Thailand...
April 1, 2017: Poultry Science
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