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Alice H Lichtenstein

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https://www.readbyqxmd.com/read/27789558/recommended-dietary-pattern-to-achieve-adherence-to-the-american-heart-association-american-college-of-cardiology-aha-acc-guidelines-a-scientific-statement-from-the-american-heart-association
#1
Linda Van Horn, Jo Ann S Carson, Lawrence J Appel, Lora E Burke, Christina Economos, Wahida Karmally, Kristie Lancaster, Alice H Lichtenstein, Rachel K Johnson, Randal J Thomas, Miriam Vos, Judith Wylie-Rosett, Penny Kris-Etherton
In 2013, the American Heart Association and American College of Cardiology published the "Guideline on Lifestyle Management to Reduce Cardiovascular Risk," which was based on a systematic review originally initiated by the National Heart, Lung, and Blood Institute. The guideline supports the American Heart Association's 2020 Strategic Impact Goals for cardiovascular health promotion and disease reduction by providing more specific details for adopting evidence-based diet and lifestyle behaviors to achieve those goals...
November 29, 2016: Circulation
https://www.readbyqxmd.com/read/27787891/a-brief-dietary-assessment-predicts-executive-dysfunction-in-an-elderly-cohort-results-from-the-einstein-aging-study
#2
Erin E Sundermann, Mindy J Katz, Richard B Lipton, Alice H Lichtenstein, Carol A Derby
OBJECTIVES: To examine the association between diet and executive function, episodic memory and global verbal cognition in the Einstein Aging Study (EAS) cohort and determine whether race modifies this relationship. DESIGN: Cross-sectional. SETTING: Community. PARTICIPANTS: EAS participants without dementia who completed the Rapid Eating and Activity Assessment for Patients (REAP) (N = 492). MEASUREMENTS: The previously validated REAP is based on the 2000 U...
November 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27604773/estimating-the-reliability-of-glycemic-index-values-and-potential-sources-of-methodological-and-biological-variability
#3
Nirupa R Matthan, Lynne M Ausman, Huicui Meng, Hocine Tighiouart, Alice H Lichtenstein
BACKGROUND: The utility of glycemic index (GI) values for chronic disease risk management remains controversial. Although absolute GI value determinations for individual foods have been shown to vary significantly in individuals with diabetes, there is a dearth of data on the reliability of GI value determinations and potential sources of variability among healthy adults. OBJECTIVE: We examined the intra- and inter-individual variability in glycemic response to a single food challenge and methodologic and biological factors that potentially mediate this response...
October 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27413137/genetic-and-environmental-effects-on-body-mass-index-from-infancy-to-the-onset-of-adulthood-an-individual-based-pooled-analysis-of-45-twin-cohorts-participating-in-the-collaborative-project-of-development-of-anthropometrical-measures-in-twins-codatwins-study
#4
Karri Silventoinen, Aline Jelenkovic, Reijo Sund, Yoon-Mi Hur, Yoshie Yokoyama, Chika Honda, Jacob vB Hjelmborg, Sören Möller, Syuichi Ooki, Sari Aaltonen, Fuling Ji, Feng Ning, Zengchang Pang, Esther Rebato, Andreas Busjahn, Christian Kandler, Kimberly J Saudino, Kerry L Jang, Wendy Cozen, Amie E Hwang, Thomas M Mack, Wenjing Gao, Canqing Yu, Liming Li, Robin P Corley, Brooke M Huibregtse, Kaare Christensen, Axel Skytthe, Kirsten O Kyvik, Catherine A Derom, Robert F Vlietinck, Ruth Jf Loos, Kauko Heikkilä, Jane Wardle, Clare H Llewellyn, Abigail Fisher, Tom A McAdams, Thalia C Eley, Alice M Gregory, Mingguang He, Xiaohu Ding, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Adam D Tarnoki, David L Tarnoki, Maria A Stazi, Corrado Fagnani, Cristina D'Ippolito, Ariel Knafo-Noam, David Mankuta, Lior Abramson, S Alexandra Burt, Kelly L Klump, Judy L Silberg, Lindon J Eaves, Hermine H Maes, Robert F Krueger, Matt McGue, Shandell Pahlen, Margaret Gatz, David A Butler, Meike Bartels, Toos Cem van Beijsterveldt, Jeffrey M Craig, Richard Saffery, Duarte L Freitas, José Antonio Maia, Lise Dubois, Michel Boivin, Mara Brendgen, Ginette Dionne, Frank Vitaro, Nicholas G Martin, Sarah E Medland, Grant W Montgomery, Youngsook Chong, Gary E Swan, Ruth Krasnow, Patrik Ke Magnusson, Nancy L Pedersen, Per Tynelius, Paul Lichtenstein, Claire Ma Haworth, Robert Plomin, Gombojav Bayasgalan, Danshiitsoodol Narandalai, K Paige Harden, Elliot M Tucker-Drob, Sevgi Y Öncel, Fazil Aliev, Timothy Spector, Massimo Mangino, Genevieve Lachance, Laura A Baker, Catherine Tuvblad, Glen E Duncan, Dedra Buchwald, Gonneke Willemsen, Finn Rasmussen, Jack H Goldberg, Thorkild Ia Sørensen, Dorret I Boomsma, Jaakko Kaprio
BACKGROUND: Both genetic and environmental factors are known to affect body mass index (BMI), but detailed understanding of how their effects differ during childhood and adolescence is lacking. OBJECTIVES: We analyzed the genetic and environmental contributions to BMI variation from infancy to early adulthood and the ways they differ by sex and geographic regions representing high (North America and Australia), moderate (Europe), and low levels (East Asia) of obesogenic environments...
August 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27333805/genetic-and-environmental-influences-on-height-from-infancy-to-early-adulthood-an-individual-based-pooled-analysis-of-45-twin-cohorts
#5
Aline Jelenkovic, Reijo Sund, Yoon-Mi Hur, Yoshie Yokoyama, Jacob V B Hjelmborg, Sören Möller, Chika Honda, Patrik K E Magnusson, Nancy L Pedersen, Syuichi Ooki, Sari Aaltonen, Maria A Stazi, Corrado Fagnani, Cristina D'Ippolito, Duarte L Freitas, José Antonio Maia, Fuling Ji, Feng Ning, Zengchang Pang, Esther Rebato, Andreas Busjahn, Christian Kandler, Kimberly J Saudino, Kerry L Jang, Wendy Cozen, Amie E Hwang, Thomas M Mack, Wenjing Gao, Canqing Yu, Liming Li, Robin P Corley, Brooke M Huibregtse, Catherine A Derom, Robert F Vlietinck, Ruth J F Loos, Kauko Heikkilä, Jane Wardle, Clare H Llewellyn, Abigail Fisher, Tom A McAdams, Thalia C Eley, Alice M Gregory, Mingguang He, Xiaohu Ding, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Adam D Tarnoki, David L Tarnoki, Ariel Knafo-Noam, David Mankuta, Lior Abramson, S Alexandra Burt, Kelly L Klump, Judy L Silberg, Lindon J Eaves, Hermine H Maes, Robert F Krueger, Matt McGue, Shandell Pahlen, Margaret Gatz, David A Butler, Meike Bartels, Toos C E M van Beijsterveldt, Jeffrey M Craig, Richard Saffery, Lise Dubois, Michel Boivin, Mara Brendgen, Ginette Dionne, Frank Vitaro, Nicholas G Martin, Sarah E Medland, Grant W Montgomery, Gary E Swan, Ruth Krasnow, Per Tynelius, Paul Lichtenstein, Claire M A Haworth, Robert Plomin, Gombojav Bayasgalan, Danshiitsoodol Narandalai, K Paige Harden, Elliot M Tucker-Drob, Timothy Spector, Massimo Mangino, Genevieve Lachance, Laura A Baker, Catherine Tuvblad, Glen E Duncan, Dedra Buchwald, Gonneke Willemsen, Axel Skytthe, Kirsten O Kyvik, Kaare Christensen, Sevgi Y Öncel, Fazil Aliev, Finn Rasmussen, Jack H Goldberg, Thorkild I A Sørensen, Dorret I Boomsma, Jaakko Kaprio, Karri Silventoinen
Height variation is known to be determined by both genetic and environmental factors, but a systematic description of how their influences differ by sex, age and global regions is lacking. We conducted an individual-based pooled analysis of 45 twin cohorts from 20 countries, including 180,520 paired measurements at ages 1-19 years. The proportion of height variation explained by shared environmental factors was greatest in early childhood, but these effects remained present until early adulthood. Accordingly, the relative genetic contribution increased with age and was greatest in adolescence (up to 0...
June 23, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27316915/french-intensive-care-society-international-congress-r%C3%A3-animation-2016
#6
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Annals of Intensive Care
https://www.readbyqxmd.com/read/27303684/manipulation-of-host-diet-to-reduce-gastrointestinal-colonization-by-the-opportunistic-pathogen-candida-albicans
#7
Kearney T W Gunsalus, Stephanie N Tornberg-Belanger, Nirupa R Matthan, Alice H Lichtenstein, Carol A Kumamoto
Candida albicans, the most common human fungal pathogen, can cause systemic infections with a mortality rate of ~40%. Infections arise from colonization of the gastrointestinal (GI) tract, where C. albicans is part of the normal microflora. Reducing colonization in at-risk patients using antifungal drugs prevents C. albicans-associated mortalities. C. albicans provides a clinically relevant system for studying the relationship between diet and the microbiota as it relates to commensalism and pathogenicity...
January 2016: MSphere
https://www.readbyqxmd.com/read/27184271/the-2015-dietary-guidelines-advisory-committee-scientific-report-development-and-major-conclusions
#8
REVIEW
Barbara E Millen, Steve Abrams, Lucile Adams-Campbell, Cheryl Am Anderson, J Thomas Brenna, Wayne W Campbell, Steven Clinton, Frank Hu, Miriam Nelson, Marian L Neuhouser, Rafael Perez-Escamilla, Anna Maria Siega-Riz, Mary Story, Alice H Lichtenstein
The Dietary Guidelines for Americans (DGA) is published every 5 y jointly by the Department of Health and Human Services (HHS) and the USDA and provides a framework for US-based food and nutrition programs, health promotion and disease prevention initiatives, and research priorities. Summarized in this report are the methods, major conclusions, and recommendations of the Scientific Report of the 2015 US Dietary Guidelines Advisory Committee (DGAC). Early in the process, the DGAC developed a conceptual model and formulated questions to examine nutritional risk and determinants and impact of dietary patterns in relation to numerous health outcomes among individuals aged ≥2 y...
May 2016: Advances in Nutrition
https://www.readbyqxmd.com/read/27150288/dietary-supplements-and-disease-prevention-a-global-overview
#9
REVIEW
Susanne Rautiainen, JoAnn E Manson, Alice H Lichtenstein, Howard D Sesso
Dietary supplements are widely used and offer the potential to improve health if appropriately targeted to those in need. Inadequate nutrition and micronutrient deficiencies are prevalent conditions that adversely affect global health. Although improvements in diet quality are essential to address these issues, dietary supplements and/or food fortification could help meet requirements for individuals at risk of deficiencies. For example, supplementation with vitamin A and iron in developing countries, where women of reproductive age, infants and children often have deficiencies; with folic acid among women of reproductive age and during pregnancy; with vitamin D among infants and children; and with calcium and vitamin D to ensure bone health among adults aged ≥65 years...
July 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/26864364/associations-of-erythrocyte-fatty-acid-patterns-with-insulin-resistance
#10
Sherman J Bigornia, Alice H Lichtenstein, William S Harris, Katherine L Tucker
BACKGROUND: Synergistic or additive effects or both on cardiometabolic risk may be missed by examining individual fatty acids (FAs). A pattern analysis may be a more useful approach. In addition, it remains unclear whether erythrocyte FA composition relates to insulin resistance among Hispanics/Latinos. OBJECTIVE: We derived erythrocyte FA patterns for a Puerto Rican cohort and examined their association with diet and insulin resistance in cross-sectional and prospective analyses...
March 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/26503881/fruits-and-vegetables-get-a-golden-halo-once-again-is-there-more-to-the-story
#11
EDITORIAL
Alice H Lichtenstein
No abstract text is available yet for this article.
November 24, 2015: Circulation
https://www.readbyqxmd.com/read/26469644/national-dissemination-of-strongwomen-healthy-hearts-a-community-based-program-to-reduce-risk-of-cardiovascular-disease-among-midlife-and-older-women
#12
Sara C Folta, Rebecca A Seguin, Kenneth K H Chui, Valerie Clark, Marilyn A Corbin, Jeanne P Goldberg, Eleanor Heidkamp-Young, Alice H Lichtenstein, Nancy Wiker, Miriam E Nelson
OBJECTIVES: We describe the national dissemination of an evidence-based community cardiovascular disease prevention program for midlife and older women using the RE-AIM (reach effectiveness adoption implementation maintenance) framework and share key lessons learned during translation. METHODS: In a 2010 to 2014 collaboration between the StrongWomen program and the National Extension Association of Family and Consumer Sciences, we assessed reach, adoption, implementation, and maintenance using survey methods, and we assessed effectiveness using a pretest-posttest within-participants design, with weight change as the primary outcome...
December 2015: American Journal of Public Health
https://www.readbyqxmd.com/read/26450668/detection-of-atherosclerotic-lesions-and-intimal-macrophages-using-cd36-targeted-nanovesicles
#13
Shufang Nie, Jia Zhang, Raul Martinez-Zaguilan, Souad Sennoune, Md Nazir Hossen, Alice H Lichtenstein, Jun Cao, Gary E Meyerrose, Ralph Paone, Suthipong Soontrapa, Zhaoyang Fan, Shu Wang
Current approaches to the diagnosis and therapy of atherosclerosis cannot target lesion-determinant cells in the artery wall. Intimal macrophage infiltration promotes atherosclerotic lesion development by facilitating the accumulation of oxidized low-density lipoproteins (oxLDL) and increasing inflammatory responses. The presence of these cells is positively associated with lesion progression, severity and destabilization. Hence, they are an important diagnostic and therapeutic target. The objective of this study was to noninvasively assess the distribution and accumulation of intimal macrophages using CD36-targeted nanovesicles...
December 28, 2015: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/26383251/lifestyle-behaviors-in-metabolically-healthy-and-unhealthy-overweight-and-obese-women-a-preliminary-study
#14
Sarah M Camhi, Scott E Crouter, Laura L Hayman, Aviva Must, Alice H Lichtenstein
BACKGROUND: Few studies have examined dietary data or objective measures of physical activity (PA) and sedentary behavior among metabolically healthy overweight/obese (MHO) and metabolically unhealthy overweight/obese (MUO). Thus, the purpose is to determine whether PA, sedentary behavior and/or diet differ between MHO and MUO in a sample of young women. METHODS: Forty-six overweight/obese (BMI ≥25 kg/m2) African American and Caucasian women 19-35 years were classified by cardiometabolic risk factors, including elevated blood pressure, triglyceride, glucose and C-reactive protein, low high density lipoprotein, and insulin resistance (MUO ≥2; MHO, <2)...
2015: PloS One
https://www.readbyqxmd.com/read/26346989/reducing-sodium-intake-in-children-a-public-health-investment
#15
Lawrence J Appel, Alice H Lichtenstein, Emily A Callahan, Alan Sinaiko, Linda Van Horn, Laurie Whitsel
The antecedents of elevated blood pressure (BP) and its major consequences (cardiovascular disease and stroke) begin in childhood. Higher levels of BP early in life track into adulthood and are associated with subclinical target organ damage in children and adults. Diet behaviors, including the choice of high sodium containing foods, are established during childhood. On average, children, ages 2-19, consume more than 3,100 mg of sodium per day, with substantially greater sodium intakes in boys than girls. Importantly, studies show that lowering sodium intake in children lowers blood pressure...
September 2015: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/26337138/zygosity-differences-in-height-and-body-mass-index-of-twins-from-infancy-to-old-age-a-study-of-the-codatwins-project
#16
Aline Jelenkovic, Yoshie Yokoyama, Reijo Sund, Chika Honda, Leonie H Bogl, Sari Aaltonen, Fuling Ji, Feng Ning, Zengchang Pang, Juan R Ordoñana, Juan F Sánchez-Romera, Lucia Colodro-Conde, S Alexandra Burt, Kelly L Klump, Sarah E Medland, Grant W Montgomery, Christian Kandler, Tom A McAdams, Thalia C Eley, Alice M Gregory, Kimberly J Saudino, Lise Dubois, Michel Boivin, Adam D Tarnoki, David L Tarnoki, Claire M A Haworth, Robert Plomin, Sevgi Y Öncel, Fazil Aliev, Maria A Stazi, Corrado Fagnani, Cristina D'Ippolito, Jeffrey M Craig, Richard Saffery, Sisira H Siribaddana, Matthew Hotopf, Athula Sumathipala, Fruhling Rijsdijk, Timothy Spector, Massimo Mangino, Genevieve Lachance, Margaret Gatz, David A Butler, Gombojav Bayasgalan, Danshiitsoodol Narandalai, Duarte L Freitas, José Antonio Maia, K Paige Harden, Elliot M Tucker-Drob, Bia Kim, Youngsook Chong, Changhee Hong, Hyun Jung Shin, Kaare Christensen, Axel Skytthe, Kirsten O Kyvik, Catherine A Derom, Robert F Vlietinck, Ruth J F Loos, Wendy Cozen, Amie E Hwang, Thomas M Mack, Mingguang He, Xiaohu Ding, Billy Chang, Judy L Silberg, Lindon J Eaves, Hermine H Maes, Tessa L Cutler, John L Hopper, Kelly Aujard, Patrik K E Magnusson, Nancy L Pedersen, Anna K Dahl Aslan, Yun-Mi Song, Sarah Yang, Kayoung Lee, Laura A Baker, Catherine Tuvblad, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Kauko Heikkilä, Qihua Tan, Dongfeng Zhang, Gary E Swan, Ruth Krasnow, Kerry L Jang, Ariel Knafo-Noam, David Mankuta, Lior Abramson, Paul Lichtenstein, Robert F Krueger, Matt McGue, Shandell Pahlen, Per Tynelius, Glen E Duncan, Dedra Buchwald, Robin P Corley, Brooke M Huibregtse, Tracy L Nelson, Keith E Whitfield, Carol E Franz, William S Kremen, Michael J Lyons, Syuichi Ooki, Ingunn Brandt, Thomas Sevenius Nilsen, Fujio Inui, Mikio Watanabe, Meike Bartels, Toos C E M van Beijsterveldt, Jane Wardle, Clare H Llewellyn, Abigail Fisher, Esther Rebato, Nicholas G Martin, Yoshinori Iwatani, Kazuo Hayakawa, Joohon Sung, Jennifer R Harris, Gonneke Willemsen, Andreas Busjahn, Jack H Goldberg, Finn Rasmussen, Yoon-Mi Hur, Dorret I Boomsma, Thorkild I A Sørensen, Jaakko Kaprio, Karri Silventoinen
A trend toward greater body size in dizygotic (DZ) than in monozygotic (MZ) twins has been suggested by some but not all studies, and this difference may also vary by age. We analyzed zygosity differences in mean values and variances of height and body mass index (BMI) among male and female twins from infancy to old age. Data were derived from an international database of 54 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins), and included 842,951 height and BMI measurements from twins aged 1 to 102 years...
October 2015: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/26043861/comparison-of-plasma-alkylresorcinols-ar-and-urinary-ar-metabolites-as-biomarkers-of-compliance-in-a-short-term-whole-grain-intervention-study
#17
Nicola M McKeown, Matti Marklund, Jiantao Ma, Alastair B Ross, Alice H Lichtenstein, Kara A Livingston, Paul F Jacques, Helen M Rasmussen, Jeffrey B Blumberg, C-Y Oliver Chen
PURPOSE: Alkylresorcinols (AR) are phenolic lipids present in the bran of wheat and rye. Plasma AR and their urinary metabolites may be suitable biomarkers of whole-grain (WG) wheat and rye consumption. The objective of this study was to examine plasma AR and urinary AR metabolites in response to WG wheat consumption. METHODS: In a randomized crossover study, 19 subjects (10 males, 9 females; BMI 22.0 kg/m(2); age 26 years) incorporated either 3 servings (48 g) or 6 servings (96 g) of WG wheat daily into their regular diet for 1 week...
April 2016: European Journal of Nutrition
https://www.readbyqxmd.com/read/26014041/the-codatwins-project-the-cohort-description-of-collaborative-project-of-development-of-anthropometrical-measures-in-twins-to-study-macro-environmental-variation-in-genetic-and-environmental-effects-on-anthropometric-traits
#18
Karri Silventoinen, Aline Jelenkovic, Reijo Sund, Chika Honda, Sari Aaltonen, Yoshie Yokoyama, Adam D Tarnoki, David L Tarnoki, Feng Ning, Fuling Ji, Zengchang Pang, Juan R Ordoñana, Juan F Sánchez-Romera, Lucia Colodro-Conde, S Alexandra Burt, Kelly L Klump, Sarah E Medland, Grant W Montgomery, Christian Kandler, Tom A McAdams, Thalia C Eley, Alice M Gregory, Kimberly J Saudino, Lise Dubois, Michel Boivin, Claire M A Haworth, Robert Plomin, Sevgi Y Öncel, Fazil Aliev, Maria A Stazi, Corrado Fagnani, Cristina D'Ippolito, Jeffrey M Craig, Richard Saffery, Sisira H Siribaddana, Matthew Hotopf, Athula Sumathipala, Timothy Spector, Massimo Mangino, Genevieve Lachance, Margaret Gatz, David A Butler, Gombojav Bayasgalan, Danshiitsoodol Narandalai, Duarte L Freitas, José Antonio Maia, K Paige Harden, Elliot M Tucker-Drob, Kaare Christensen, Axel Skytthe, Kirsten O Kyvik, Changhee Hong, Youngsook Chong, Catherine A Derom, Robert F Vlietinck, Ruth J F Loos, Wendy Cozen, Amie E Hwang, Thomas M Mack, Mingguang He, Xiaohu Ding, Billy Chang, Judy L Silberg, Lindon J Eaves, Hermine H Maes, Tessa L Cutler, John L Hopper, Kelly Aujard, Patrik K E Magnusson, Nancy L Pedersen, Anna K Dahl Aslan, Yun-Mi Song, Sarah Yang, Kayoung Lee, Laura A Baker, Catherine Tuvblad, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Kauko Heikkilä, Qihua Tan, Dongfeng Zhang, Gary E Swan, Ruth Krasnow, Kerry L Jang, Ariel Knafo-Noam, David Mankuta, Lior Abramson, Paul Lichtenstein, Robert F Krueger, Matt McGue, Shandell Pahlen, Per Tynelius, Glen E Duncan, Dedra Buchwald, Robin P Corley, Brooke M Huibregtse, Tracy L Nelson, Keith E Whitfield, Carol E Franz, William S Kremen, Michael J Lyons, Syuichi Ooki, Ingunn Brandt, Thomas Sevenius Nilsen, Fujio Inui, Mikio Watanabe, Meike Bartels, Toos C E M van Beijsterveldt, Jane Wardle, Clare H Llewellyn, Abigail Fisher, Esther Rebato, Nicholas G Martin, Yoshinori Iwatani, Kazuo Hayakawa, Finn Rasmussen, Joohon Sung, Jennifer R Harris, Gonneke Willemsen, Andreas Busjahn, Jack H Goldberg, Dorret I Boomsma, Yoon-Mi Hur, Thorkild I A Sørensen, Jaakko Kaprio
For over 100 years, the genetics of human anthropometric traits has attracted scientific interest. In particular, height and body mass index (BMI, calculated as kg/m2) have been under intensive genetic research. However, it is still largely unknown whether and how heritability estimates vary between human populations. Opportunities to address this question have increased recently because of the establishment of many new twin cohorts and the increasing accumulation of data in established twin cohorts. We started a new research project to analyze systematically (1) the variation of heritability estimates of height, BMI and their trajectories over the life course between birth cohorts, ethnicities and countries, and (2) to study the effects of birth-related factors, education and smoking on these anthropometric traits and whether these effects vary between twin cohorts...
August 2015: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/25937589/healthy-eating-index-and-metabolically-healthy-obesity-in-u-s-adolescents-and-adults
#19
Sarah M Camhi, E Whitney Evans, Laura L Hayman, Alice H Lichtenstein, Aviva Must
OBJECTIVE: To determine whether dietary quality differs between metabolically-healthy-obese (MHO) and metabolically-abnormal-obesity (MAO) in a nationally representative sample. METHODS: National Health and Nutrition Examination Survey (NHANES) data (2007-2008; 2009-2010) were used to identify obese adolescents (≥95th body mass index (BMI) %tile) and adults (≥30kg/m(2)). MHO was defined as <2 abnormal cardiometabolic risk factors (elevated blood pressure, triglycerides, glucose, low high density lipoprotein cholesterol (HDL-C); or on medications)...
August 2015: Preventive Medicine
https://www.readbyqxmd.com/read/25921297/docosahexaenoic-acid-differentially-affects-tnf%C3%AE-and-il-6-expression-in-lps-stimulated-raw-264-7-murine-macrophages
#20
Kaori L Honda, Stefania Lamon-Fava, Nirupa R Matthan, Dayong Wu, Alice H Lichtenstein
Docosahexaenoic acid (DHA) is generally reported to have anti-inflammatory properties, however, prior work has documented differential effects on individual pro-inflammatory cytokines: reduced IL-6, but not TNFα, mRNA expression in macrophages. To elucidate the mechanism, the roles of prostaglandin E2 (PGE2), cyclic AMP response element-binding protein (CREB), and NFκB were examined in RAW 264.7 macrophages. DHA did not influence CREB activity, but significantly reduced PGE2 production by 41% and NFκB activity by 32%...
June 2015: Prostaglandins, Leukotrienes, and Essential Fatty Acids
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