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Alice H Lichtenstein

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https://www.readbyqxmd.com/read/28620111/dietary-fats-and-cardiovascular-disease-a-presidential-advisory-from-the-american-heart-association
#1
REVIEW
Frank M Sacks, Alice H Lichtenstein, Jason H Y Wu, Lawrence J Appel, Mark A Creager, Penny M Kris-Etherton, Michael Miller, Eric B Rimm, Lawrence L Rudel, Jennifer G Robinson, Neil J Stone, Linda V Van Horn
Cardiovascular disease (CVD) is the leading global cause of death, accounting for 17.3 million deaths per year. Preventive treatment that reduces CVD by even a small percentage can substantially reduce, nationally and globally, the number of people who develop CVD and the costs of caring for them. This American Heart Association presidential advisory on dietary fats and CVD reviews and discusses the scientific evidence, including the most recent studies, on the effects of dietary saturated fat intake and its replacement by other types of fats and carbohydrates on CVD...
June 15, 2017: Circulation
https://www.readbyqxmd.com/read/28566309/in-memoriam
#2
Alice H Lichtenstein
No abstract text is available yet for this article.
May 31, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28465822/does-the-sex-of-one-s-co-twin-affect-height-and-bmi-in-adulthood-a-study-of-dizygotic-adult-twins-from-31-cohorts
#3
Leonie H Bogl, Aline Jelenkovic, Eero Vuoksimaa, Linda Ahrenfeldt, Kirsi H Pietiläinen, Maria A Stazi, Corrado Fagnani, Cristina D'Ippolito, Yoon-Mi Hur, Hoe-Uk Jeong, Judy L Silberg, Lindon J Eaves, Hermine H Maes, Gombojav Bayasgalan, Danshiitsoodol Narandalai, Tessa L Cutler, Christian Kandler, Kerry L Jang, Kaare Christensen, Axel Skytthe, Kirsten O Kyvik, Wendy Cozen, Amie E Hwang, Thomas M Mack, Catherine A Derom, Robert F Vlietinck, Tracy L Nelson, Keith E Whitfield, Robin P Corley, Brooke M Huibregtse, Tom A McAdams, Thalia C Eley, Alice M Gregory, Robert F Krueger, Matt McGue, Shandell Pahlen, Gonneke Willemsen, Meike Bartels, Toos C E M van Beijsterveldt, Zengchang Pang, Qihua Tan, Dongfeng Zhang, Nicholas G Martin, Sarah E Medland, Grant W Montgomery, Jacob V B Hjelmborg, Esther Rebato, Gary E Swan, Ruth Krasnow, Andreas Busjahn, Paul Lichtenstein, Sevgi Y Öncel, Fazil Aliev, Laura A Baker, Catherine Tuvblad, Sisira H Siribaddana, Matthew Hotopf, Athula Sumathipala, Fruhling Rijsdijk, Patrik K E Magnusson, Nancy L Pedersen, Anna K Dahl Aslan, Juan R Ordoñana, Juan F Sánchez-Romera, Lucia Colodro-Conde, Glen E Duncan, Dedra Buchwald, Adam D Tarnoki, David L Tarnoki, Yoshie Yokoyama, John L Hopper, Ruth J F Loos, Dorret I Boomsma, Thorkild I A Sørensen, Karri Silventoinen, Jaakko Kaprio
BACKGROUND: The comparison of traits in twins from opposite-sex (OS) and same-sex (SS) dizygotic twin pairs is considered a proxy measure of prenatal hormone exposure. To examine possible prenatal hormonal influences on anthropometric traits, we compared mean height, body mass index (BMI), and the prevalence of being overweight or obese between men and women from OS and SS dizygotic twin pairs. METHODS: The data were derived from the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) database, and included 68,494 SS and 53,808 OS dizygotic twin individuals above the age of 20 years from 31 twin cohorts representing 19 countries...
2017: Biology of Sex Differences
https://www.readbyqxmd.com/read/28356272/choline-and-its-metabolites-are-differently-associated-with-cardiometabolic-risk-factors-history-of-cardiovascular-disease-and-mri-documented-cerebrovascular-disease-in-older-adults
#4
Annie J Roe, Shucha Zhang, Rafeeque A Bhadelia, Elizabeth J Johnson, Alice H Lichtenstein, Gail T Rogers, Irwin H Rosenberg, Caren E Smith, Steven H Zeisel, Tammy M Scott
Background: There is a potential role of choline in cardiovascular and cerebrovascular disease through its involvement in lipid and one-carbon metabolism.Objective: We evaluated the associations of plasma choline and choline-related compounds with cardiometabolic risk factors, history of cardiovascular disease, and cerebrovascular pathology.Design: A cross-sectional subset of the Nutrition, Aging, and Memory in Elders cohort who had undergone MRI of the brain (n = 296; mean ± SD age: 73 ± 8.1 y) was assessed...
June 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28289069/omega-3-polyunsaturated-fatty-acid-fish-oil-supplementation-and-the-prevention-of-clinical-cardiovascular-disease-a-science-advisory-from-the-american-heart-association
#5
REVIEW
David S Siscovick, Thomas A Barringer, Amanda M Fretts, Jason H Y Wu, Alice H Lichtenstein, Rebecca B Costello, Penny M Kris-Etherton, Terry A Jacobson, Mary B Engler, Heather M Alger, Lawrence J Appel, Dariush Mozaffarian
Multiple randomized controlled trials (RCTs) have assessed the effects of supplementation with eicosapentaenoic acid plus docosahexaenoic acid (omega-3 polyunsaturated fatty acids, commonly called fish oils) on the occurrence of clinical cardiovascular diseases. Although the effects of supplementation for the primary prevention of clinical cardiovascular events in the general population have not been examined, RCTs have assessed the role of supplementation in secondary prevention among patients with diabetes mellitus and prediabetes, patients at high risk of cardiovascular disease, and those with prevalent coronary heart disease...
April 11, 2017: Circulation
https://www.readbyqxmd.com/read/28251934/longitudinal-study-of-alcohol-consumption-and-hdl-concentrations-a-community-based-study
#6
Shue Huang, Junjuan Li, Gregory C Shearer, Alice H Lichtenstein, Xiaoming Zheng, Yuntao Wu, Cheng Jin, Shouling Wu, Xiang Gao
Background: In cross-sectional studies and short-term clinical trials, it has been suggested that there is a positive dose-response relation between alcohol consumption and HDL concentrations. However, prospective data have been limited.Objective: We sought to determine the association between total alcohol intake, the type of alcohol-containing beverage, and the 6-y (2006-2012) longitudinal change in HDL-cholesterol concentrations in a community-based cohort.Design: A total of 71,379 Chinese adults (mean age: 50 y) who were free of cardiovascular diseases and cancer and did not use cholesterol-lowering agents during follow-up were included in the study...
April 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28202475/effect-of-macronutrients-and-fiber-on-postprandial-glycemic-responses-and-meal-glycemic-index-and-glycemic-load-value-determinations
#7
Huicui Meng, Nirupa R Matthan, Lynne M Ausman, Alice H Lichtenstein
Background: The potential confounding effect of different amounts and proportions of macronutrients across eating patterns on meal or dietary glycemic index (GI) and glycemic load (GL) value determinations has remained partially unaddressed.Objective: The study aimed to determine the effects of different amounts of macronutrients and fiber on measured meal GI and GL values.Design: Four studies were conducted during which participants [n = 20-22; women: 50%; age: 50-80 y; body mass index (in kg/m(2)): 25-30)] received food challenges containing different amounts of the variable nutrient in a random order...
April 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28031418/peripheral-inflammatory-biomarkers-for-myocardial-infarction-risk-a-prospective-community-based-study
#8
Zhijun Wu, Zhe Huang, Wei Jin, Eric B Rimm, Alice H Lichtenstein, Penny M Kris-Etherton, Shouling Wu, Xiang Gao
BACKGROUND: Most previous studies regarding chronic inflammation and risk of myocardial infarction (MI) have lacked repeated measures of high-sensitivity C-reactive protein (hs-CRP) and/or white blood cell (WBC) count over time. We examined whether cumulative average and longitudinal changes in these biomarkers were associated with subsequent MI risk. METHODS: In this prospective, community-based study, we included 82544 Chinese participants [66796 men and 15748 women; mean (SD) age 55...
March 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/27986651/effects-of-pcsk9-inhibition-with-alirocumab-on-lipoprotein-metabolism-in-healthy-humans
#9
Gissette Reyes-Soffer, Marianna Pavlyha, Colleen Ngai, Tiffany Thomas, Stephen Holleran, Rajasekhar Ramakrishnan, Wahida Karmally, Renu Nandakumar, Nelson Fontanez, Joseph Obunike, Santica M Marcovina, Alice H Lichtenstein, Nirupa R Matthan, James Matta, Magali Maroccia, Frederic Becue, Franck Poitiers, Brian Swanson, Lisa Cowan, William J Sasiela, Howard K Surks, Henry N Ginsberg
BACKGROUND: Alirocumab, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 (PCSK9), lowers plasma low-density lipoprotein (LDL) cholesterol and apolipoprotein B100 (apoB). Although studies in mice and cells have identified increased hepatic LDL receptors as the basis for LDL lowering by PCSK9 inhibitors, there have been no human studies characterizing the effects of PCSK9 inhibitors on lipoprotein metabolism. In particular, it is not known whether inhibition of PCSK9 has any effects on very low-density lipoprotein or intermediate-density lipoprotein (IDL) metabolism...
January 24, 2017: Circulation
https://www.readbyqxmd.com/read/27964777/genetic-and-environmental-influences-on-adult-human-height-across-birth-cohorts-from-1886-to-1994
#10
Aline Jelenkovic, Yoon-Mi Hur, Reijo Sund, Yoshie Yokoyama, Sisira H Siribaddana, Matthew Hotopf, Athula Sumathipala, Fruhling Rijsdijk, Qihua Tan, Dongfeng Zhang, Zengchang Pang, Sari Aaltonen, Kauko Heikkilä, Sevgi Y Öncel, Fazil Aliev, Esther Rebato, Adam D Tarnoki, David L Tarnoki, Kaare Christensen, Axel Skytthe, Kirsten O Kyvik, Judy L Silberg, Lindon J Eaves, Hermine H Maes, Tessa L Cutler, John L Hopper, Juan R Ordoñana, Juan F Sánchez-Romera, Lucia Colodro-Conde, Wendy Cozen, Amie E Hwang, Thomas M Mack, Joohon Sung, Yun-Mi Song, Sarah Yang, Kayoung Lee, Carol E Franz, William S Kremen, Michael J Lyons, Andreas Busjahn, Tracy L Nelson, Keith E Whitfield, Christian Kandler, Kerry L Jang, Margaret Gatz, David A Butler, Maria A Stazi, Corrado Fagnani, Cristina D'Ippolito, Glen E Duncan, Dedra Buchwald, Catherine A Derom, Robert F Vlietinck, Ruth Jf Loos, Nicholas G Martin, Sarah E Medland, Grant W Montgomery, Hoe-Uk Jeong, Gary E Swan, Ruth Krasnow, Patrik Ke Magnusson, Nancy L Pedersen, Anna K Dahl-Aslan, Tom A McAdams, Thalia C Eley, Alice M Gregory, Per Tynelius, Laura A Baker, Catherine Tuvblad, Gombojav Bayasgalan, Danshiitsoodol Narandalai, Paul Lichtenstein, Timothy D Spector, Massimo Mangino, Genevieve Lachance, Meike Bartels, Toos Cem van Beijsterveldt, Gonneke Willemsen, S Alexandra Burt, Kelly L Klump, Jennifer R Harris, Ingunn Brandt, Thomas Sevenius Nilsen, Robert F Krueger, Matt McGue, Shandell Pahlen, Robin P Corley, Jacob V B Hjelmborg, Jack H Goldberg, Yoshinori Iwatani, Mikio Watanabe, Chika Honda, Fujio Inui, Finn Rasmussen, Brooke M Huibregtse, Dorret I Boomsma, Thorkild I A Sørensen, Jaakko Kaprio, Karri Silventoinen
Human height variation is determined by genetic and environmental factors, but it remains unclear whether their influences differ across birth-year cohorts. We conducted an individual-based pooled analysis of 40 twin cohorts including 143,390 complete twin pairs born 1886-1994. Although genetic variance showed a generally increasing trend across the birth-year cohorts, heritability estimates (0.69-0.84 in men and 0.53-0.78 in women) did not present any clear pattern of secular changes. Comparing geographic-cultural regions (Europe, North America and Australia, and East Asia), total height variance was greatest in North America and Australia and lowest in East Asia, but no clear pattern in the heritability estimates across the birth-year cohorts emerged...
December 14, 2016: ELife
https://www.readbyqxmd.com/read/27789558/recommended-dietary-pattern-to-achieve-adherence-to-the-american-heart-association-american-college-of-cardiology-aha-acc-guidelines-a-scientific-statement-from-the-american-heart-association
#11
Linda Van Horn, Jo Ann S Carson, Lawrence J Appel, Lora E Burke, Christina Economos, Wahida Karmally, Kristie Lancaster, Alice H Lichtenstein, Rachel K Johnson, Randal J Thomas, Miriam Vos, Judith Wylie-Rosett, Penny Kris-Etherton
In 2013, the American Heart Association and American College of Cardiology published the "Guideline on Lifestyle Management to Reduce Cardiovascular Risk," which was based on a systematic review originally initiated by the National Heart, Lung, and Blood Institute. The guideline supports the American Heart Association's 2020 Strategic Impact Goals for cardiovascular health promotion and disease reduction by providing more specific details for adopting evidence-based diet and lifestyle behaviors to achieve those goals...
November 29, 2016: Circulation
https://www.readbyqxmd.com/read/27787891/a-brief-dietary-assessment-predicts-executive-dysfunction-in-an-elderly-cohort-results-from-the-einstein-aging-study
#12
Erin E Sundermann, Mindy J Katz, Richard B Lipton, Alice H Lichtenstein, Carol A Derby
OBJECTIVES: To examine the association between diet and executive function, episodic memory and global verbal cognition in the Einstein Aging Study (EAS) cohort and determine whether race modifies this relationship. DESIGN: Cross-sectional. SETTING: Community. PARTICIPANTS: EAS participants without dementia who completed the Rapid Eating and Activity Assessment for Patients (REAP) (N = 492). MEASUREMENTS: The previously validated REAP is based on the 2000 U...
November 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27604773/estimating-the-reliability-of-glycemic-index-values-and-potential-sources-of-methodological-and-biological-variability
#13
Nirupa R Matthan, Lynne M Ausman, Huicui Meng, Hocine Tighiouart, Alice H Lichtenstein
BACKGROUND: The utility of glycemic index (GI) values for chronic disease risk management remains controversial. Although absolute GI value determinations for individual foods have been shown to vary significantly in individuals with diabetes, there is a dearth of data on the reliability of GI value determinations and potential sources of variability among healthy adults. OBJECTIVE: We examined the intra- and inter-individual variability in glycemic response to a single food challenge and methodologic and biological factors that potentially mediate this response...
October 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27413137/genetic-and-environmental-effects-on-body-mass-index-from-infancy-to-the-onset-of-adulthood-an-individual-based-pooled-analysis-of-45-twin-cohorts-participating-in-the-collaborative-project-of-development-of-anthropometrical-measures-in-twins-codatwins-study
#14
Karri Silventoinen, Aline Jelenkovic, Reijo Sund, Yoon-Mi Hur, Yoshie Yokoyama, Chika Honda, Jacob vB Hjelmborg, Sören Möller, Syuichi Ooki, Sari Aaltonen, Fuling Ji, Feng Ning, Zengchang Pang, Esther Rebato, Andreas Busjahn, Christian Kandler, Kimberly J Saudino, Kerry L Jang, Wendy Cozen, Amie E Hwang, Thomas M Mack, Wenjing Gao, Canqing Yu, Liming Li, Robin P Corley, Brooke M Huibregtse, Kaare Christensen, Axel Skytthe, Kirsten O Kyvik, Catherine A Derom, Robert F Vlietinck, Ruth Jf Loos, Kauko Heikkilä, Jane Wardle, Clare H Llewellyn, Abigail Fisher, Tom A McAdams, Thalia C Eley, Alice M Gregory, Mingguang He, Xiaohu Ding, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Adam D Tarnoki, David L Tarnoki, Maria A Stazi, Corrado Fagnani, Cristina D'Ippolito, Ariel Knafo-Noam, David Mankuta, Lior Abramson, S Alexandra Burt, Kelly L Klump, Judy L Silberg, Lindon J Eaves, Hermine H Maes, Robert F Krueger, Matt McGue, Shandell Pahlen, Margaret Gatz, David A Butler, Meike Bartels, Toos Cem van Beijsterveldt, Jeffrey M Craig, Richard Saffery, Duarte L Freitas, José Antonio Maia, Lise Dubois, Michel Boivin, Mara Brendgen, Ginette Dionne, Frank Vitaro, Nicholas G Martin, Sarah E Medland, Grant W Montgomery, Youngsook Chong, Gary E Swan, Ruth Krasnow, Patrik Ke Magnusson, Nancy L Pedersen, Per Tynelius, Paul Lichtenstein, Claire Ma Haworth, Robert Plomin, Gombojav Bayasgalan, Danshiitsoodol Narandalai, K Paige Harden, Elliot M Tucker-Drob, Sevgi Y Öncel, Fazil Aliev, Timothy Spector, Massimo Mangino, Genevieve Lachance, Laura A Baker, Catherine Tuvblad, Glen E Duncan, Dedra Buchwald, Gonneke Willemsen, Finn Rasmussen, Jack H Goldberg, Thorkild Ia Sørensen, Dorret I Boomsma, Jaakko Kaprio
BACKGROUND: Both genetic and environmental factors are known to affect body mass index (BMI), but detailed understanding of how their effects differ during childhood and adolescence is lacking. OBJECTIVES: We analyzed the genetic and environmental contributions to BMI variation from infancy to early adulthood and the ways they differ by sex and geographic regions representing high (North America and Australia), moderate (Europe), and low levels (East Asia) of obesogenic environments...
August 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27333805/genetic-and-environmental-influences-on-height-from-infancy-to-early-adulthood-an-individual-based-pooled-analysis-of-45-twin-cohorts
#15
Aline Jelenkovic, Reijo Sund, Yoon-Mi Hur, Yoshie Yokoyama, Jacob V B Hjelmborg, Sören Möller, Chika Honda, Patrik K E Magnusson, Nancy L Pedersen, Syuichi Ooki, Sari Aaltonen, Maria A Stazi, Corrado Fagnani, Cristina D'Ippolito, Duarte L Freitas, José Antonio Maia, Fuling Ji, Feng Ning, Zengchang Pang, Esther Rebato, Andreas Busjahn, Christian Kandler, Kimberly J Saudino, Kerry L Jang, Wendy Cozen, Amie E Hwang, Thomas M Mack, Wenjing Gao, Canqing Yu, Liming Li, Robin P Corley, Brooke M Huibregtse, Catherine A Derom, Robert F Vlietinck, Ruth J F Loos, Kauko Heikkilä, Jane Wardle, Clare H Llewellyn, Abigail Fisher, Tom A McAdams, Thalia C Eley, Alice M Gregory, Mingguang He, Xiaohu Ding, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Adam D Tarnoki, David L Tarnoki, Ariel Knafo-Noam, David Mankuta, Lior Abramson, S Alexandra Burt, Kelly L Klump, Judy L Silberg, Lindon J Eaves, Hermine H Maes, Robert F Krueger, Matt McGue, Shandell Pahlen, Margaret Gatz, David A Butler, Meike Bartels, Toos C E M van Beijsterveldt, Jeffrey M Craig, Richard Saffery, Lise Dubois, Michel Boivin, Mara Brendgen, Ginette Dionne, Frank Vitaro, Nicholas G Martin, Sarah E Medland, Grant W Montgomery, Gary E Swan, Ruth Krasnow, Per Tynelius, Paul Lichtenstein, Claire M A Haworth, Robert Plomin, Gombojav Bayasgalan, Danshiitsoodol Narandalai, K Paige Harden, Elliot M Tucker-Drob, Timothy Spector, Massimo Mangino, Genevieve Lachance, Laura A Baker, Catherine Tuvblad, Glen E Duncan, Dedra Buchwald, Gonneke Willemsen, Axel Skytthe, Kirsten O Kyvik, Kaare Christensen, Sevgi Y Öncel, Fazil Aliev, Finn Rasmussen, Jack H Goldberg, Thorkild I A Sørensen, Dorret I Boomsma, Jaakko Kaprio, Karri Silventoinen
Height variation is known to be determined by both genetic and environmental factors, but a systematic description of how their influences differ by sex, age and global regions is lacking. We conducted an individual-based pooled analysis of 45 twin cohorts from 20 countries, including 180,520 paired measurements at ages 1-19 years. The proportion of height variation explained by shared environmental factors was greatest in early childhood, but these effects remained present until early adulthood. Accordingly, the relative genetic contribution increased with age and was greatest in adolescence (up to 0...
June 23, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27316915/french-intensive-care-society-international-congress-r%C3%A3-animation-2016
#16
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Annals of Intensive Care
https://www.readbyqxmd.com/read/27303684/manipulation-of-host-diet-to-reduce-gastrointestinal-colonization-by-the-opportunistic-pathogen-candida-albicans
#17
Kearney T W Gunsalus, Stephanie N Tornberg-Belanger, Nirupa R Matthan, Alice H Lichtenstein, Carol A Kumamoto
Candida albicans, the most common human fungal pathogen, can cause systemic infections with a mortality rate of ~40%. Infections arise from colonization of the gastrointestinal (GI) tract, where C. albicans is part of the normal microflora. Reducing colonization in at-risk patients using antifungal drugs prevents C. albicans-associated mortalities. C. albicans provides a clinically relevant system for studying the relationship between diet and the microbiota as it relates to commensalism and pathogenicity...
January 2016: MSphere
https://www.readbyqxmd.com/read/27184271/the-2015-dietary-guidelines-advisory-committee-scientific-report-development-and-major-conclusions
#18
REVIEW
Barbara E Millen, Steve Abrams, Lucile Adams-Campbell, Cheryl Am Anderson, J Thomas Brenna, Wayne W Campbell, Steven Clinton, Frank Hu, Miriam Nelson, Marian L Neuhouser, Rafael Perez-Escamilla, Anna Maria Siega-Riz, Mary Story, Alice H Lichtenstein
The Dietary Guidelines for Americans (DGA) is published every 5 y jointly by the Department of Health and Human Services (HHS) and the USDA and provides a framework for US-based food and nutrition programs, health promotion and disease prevention initiatives, and research priorities. Summarized in this report are the methods, major conclusions, and recommendations of the Scientific Report of the 2015 US Dietary Guidelines Advisory Committee (DGAC). Early in the process, the DGAC developed a conceptual model and formulated questions to examine nutritional risk and determinants and impact of dietary patterns in relation to numerous health outcomes among individuals aged ≥2 y...
May 2016: Advances in Nutrition
https://www.readbyqxmd.com/read/27150288/dietary-supplements-and-disease-prevention-a-global-overview
#19
REVIEW
Susanne Rautiainen, JoAnn E Manson, Alice H Lichtenstein, Howard D Sesso
Dietary supplements are widely used and offer the potential to improve health if appropriately targeted to those in need. Inadequate nutrition and micronutrient deficiencies are prevalent conditions that adversely affect global health. Although improvements in diet quality are essential to address these issues, dietary supplements and/or food fortification could help meet requirements for individuals at risk of deficiencies. For example, supplementation with vitamin A and iron in developing countries, where women of reproductive age, infants and children often have deficiencies; with folic acid among women of reproductive age and during pregnancy; with vitamin D among infants and children; and with calcium and vitamin D to ensure bone health among adults aged ≥65 years...
July 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/26864364/associations-of-erythrocyte-fatty-acid-patterns-with-insulin-resistance
#20
Sherman J Bigornia, Alice H Lichtenstein, William S Harris, Katherine L Tucker
BACKGROUND: Synergistic or additive effects or both on cardiometabolic risk may be missed by examining individual fatty acids (FAs). A pattern analysis may be a more useful approach. In addition, it remains unclear whether erythrocyte FA composition relates to insulin resistance among Hispanics/Latinos. OBJECTIVE: We derived erythrocyte FA patterns for a Puerto Rican cohort and examined their association with diet and insulin resistance in cross-sectional and prospective analyses...
March 2016: American Journal of Clinical Nutrition
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