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https://www.readbyqxmd.com/read/27932205/cold-induced-sympathetic-tone-modifies-the-impact-of-endothelium-dependent-vasodilation-in-the-finger-pulp
#1
Tone Kristin Bergersen, Maria Skytioti, Maja Elstad
OBJECTIVE: In thermoneutral and cold subjects, the sympathetic nervous system regulates skin blood flow by adjusting frequency of the tonic vasoconstrictor impulses. However, the way these thermoregulatory impulses influence the vascular endothelium is not well known. We studied how the sympathetic nervous system influences endothelium-dependent vasodilation (EDV) caused by shear stress in skin containing arteriovenous anastomoses (AVAs) and arterioles in healthy subjects. METHODS: Thirteen healthy subjects were exposed to thermoneutral (29°C) and cold (22°C) ambient temperatures on separate days...
November 30, 2016: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/27931961/imaging-of-connective-tissue-diseases-beyond-visceral-organ-imaging
#2
REVIEW
Maurizio Cutolo, Nemanja Damjanov, Barbara Ruaro, Ana Zekovic, Vanessa Smith
Connective tissues diseases (CTDs) can also be diagnosed early by "external" and safe imaging methods beyond the visceral organ analysis. This study aims to explore various imaging techniques used in diagnosing CTDs. Skin impairment in systemic sclerosis (SSc) may be recognized and studied by the modified Rodnan skin score (mRSS), which has some drawbacks, whereas high-frequency ultrasound (US) seems advantageous for the early identification of skin involvement. Salivary gland involvement in Sjögren syndrome (SS) can be assessed using standard tests such as unstimulated salivary flow test, salivary gland scintigraphy or contrast sialography...
August 2016: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/27930432/retinal-findings-in-a-case-of-presumed-cutis-marmorata-telangiectatica-congenita
#3
Eman A Taleb, Manish P Nagpal, Navneet S Mehrotra, Kalyani Bhatt
PURPOSES: To correlate the clinical picture and fundus fluorescein angiography findings in case of presumed cutis marmorata telangiectatica congenita. METHODS: A 41-year-old woman with presumed cutis marmorata telangiectatica congenita who is a known case of hypothyroidism for the last 6 years and has bilateral peripheral retinal vascular abnormalities, peripheral retinal nonperfusion on fluorescein angiography and bilateral optic disk drusen. RESULT: A patient presented with blurring of vision in both eyes for last 6 months...
December 7, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27930376/excimer-light-treatment-for-idiopathic-guttate-hypomelanosis-a-pilot-study
#4
Jennifer R S Gordon, Kellie E Reed, Katherine R Sebastian, Ammar M Ahmed
BACKGROUND: Idiopathic guttate hypomelanosis (IGH) is a commonly acquired benign leukoderma characterized by multiple discrete, hypo- or depigmented macules often on extremities that can be aesthetically undesirable for patients. This is the first study using excimer laser for treatment. OBJECTIVE: To determine the effectiveness of excimer laser for repigmentation of idiopathic guttate hypomelanosis. METHODS AND MATERIALS: In this longitudinal, split-body controlled, single-blinded pilot study, 6 patients were treated with excimer laser for 12 weeks using the vitiligo protocol...
December 2, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27928688/combining-laser-doppler-flowmetry-measurements-with-spectral-analysis-to-study-different-microcirculatory-effects-in-human-prediabetic-and-diabetic-subjects
#5
Hsiao-Feng Hu, Hsin Hsiu, Ciao-Jyuan Sung, Chien-Hsing Lee
We aimed to identify the microcirculatory regulatory mechanisms in diabetic and prediabetic humans using a noninvasive method combining spectral analysis with laser-Doppler flowmetry (LDF) measurements on the skin surface. LDF signals were measured by a moorVMS-LDF device to measure the microcirculatory blood flow flux with a time constant of 0.001 s, a cutoff frequency of 14.9 kHz, and a sampling frequency of 40 Hz. The laser operating wavelength and output power were 400-700 nm and 6 mW, respectively...
December 7, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27924419/beneficial-effect-of-low-level-laser-therapy-in-acute-lung-injury-after-i-i-r-is-dependent-on-the-secretion-of-il-10-and-independent-of-the-tlr-myd88-signaling
#6
J L Carvalho, A Britto, A P Ligeiro de Oliveira, H Castro-Faria-Neto, R Albertini, E Anatriello, F Aimbire
The use of low-level laser for lung inflammation treatment has been evidenced in animal studies as well as clinical trials. The laser action mechanism seems to involve downregulation of neutrophil chemoattractants and transcription factors. Innate immune responses against microorganisms may be mediated by toll-like receptors (TLR). Intestinal ischemia and reperfusion (i-I/R) lead to bacterial product translocation, such as endotoxin, which consequently activates TLRs leading to intestinal and lung inflammation after gut trauma...
December 6, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27923581/uvb-irradiation-induces-rapid-changes-in-galanin-substance-p-and-c-fos-immunoreactivity-in-rat-dorsal-root-ganglia-and-spinal-cord
#7
Leila Etemadi, Lina M E Pettersson, Nils Danielsen
Recent studies have shown that UVB irradiation induces primary and secondary hyperalgesia in rats and humans peaking about 24hrs after UVB exposure. In the present study we investigated the changes in galanin, substance P and c-fos immunoreactivity in rat DRG and spinal cord at the L5 level 2-96hrs after UVB irradiation. UVB irradiation of the heel area in rats almost increased the skin blood flow two-fold 24hrs after irradiation as measured by laser Doppler technique. UVB irradiation induced a significant reduction of the proportion of galanin positive DRG neurons for all time points, except at 12hrs...
December 3, 2016: Peptides
https://www.readbyqxmd.com/read/27922281/the-effect-of-recurrent-pulsed-dye-laser-treatments-in-rosacea-patients
#8
Mark Strand Do, Gunnar Bergqvist, Shane Griffith, Emma Bergqvist
BACKGROUND: Rosacea is common chronic skin condition and is known to have a negative impact on patient's quality of life. The use of pulsed dye laser treatment to improve quality of life is well documented in the literature. Prior work has emphasized a single series of laser treatments but we investigated the effect of recurrent pulsed dye laser treatment on patient's symptomalology and quality of life. METHODS: We designed an 8 question survey about patient's rosacea symptoms, prior treatments, effectiveness of prior treatments, benefit of the laser treatments, and number of laser treatments...
December 6, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27918844/novel-method-for-facial-rejuvenation-using-er-yag-laser-equipped-with-a-spatially-modulated-ablation-module-an-open-prospective-uncontrolled-cohort-study
#9
N V Volkova, L K Glazkova, V V Khomchenko, N S Sadick
Facial aging is a complex biological process that affects the skin and superficial musculoaponeurotic system (SMAS). A new technology (RecoSMA) for skin rejuvenation based on acoustic-interference method using Er:YAG laser (2936 nm) equipped with a special module SMA that targets both the dermis and SMAS was evaluated in an open-label prospective cohort study of 100 female patients treated for facial rejuvenation. Measure of clinical improvement included investigator-rated clinical photography using the Modified Fitzpatrick Wrinkle Scale, and ultrasound measurements in the dermis a week, 30 days and six months post treatment...
December 5, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27918772/energy-based-facial-rejuvenation-advances-in-diagnosis-and-treatment
#10
Christopher J Britt, Benjamin Marcus
Importance: The market for nonsurgical, energy-based facial rejuvenation techniques has increased exponentially since lasers were first used for skin rejuvenation in 1983. Advances in this area have led to a wide range of products that require the modern facial plastic surgeon to have a large repertoire of knowledge. Objective: To serve as a guide for current trends in the development of technology, applications, and outcomes of laser and laser-related technology over the past 5 years...
December 1, 2016: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/27918009/optical-properties-of-porcine-dermis-in-the-mid-infrared-absorption-band-of-glucose
#11
Arthur Schönhals, Hans Tholl, Mathias Glasmacher, Niels Kröger-Lui, Annemarie Pucci, Wolfgang Petrich
The optical properties of skin in the mid-infrared range are not known, despite their importance for e.g. non-invasive glucose monitoring. In this paper, transmission, absorption, scattering, and reduced scattering coefficients are quantified using a custom-built goniometer based on a quantum cascade laser operated at the glucose absorption band at a wavelength of around 9.7 μm. The measurements show a strong dominance of absorption and moderate contributions from scattering. The scattered radiation is dominated by single scattering events in the forward direction (g = 0...
December 5, 2016: Analyst
https://www.readbyqxmd.com/read/27918004/what-devices-to-use-or-not-use-in-skin-of-color
#12
Murad Alam
Lasers and light sources, as well as other energy devices, including radiofrequency, ultrasound, and cold-based therapies, can be used for treatment of aging, dyschromic, or texturally uneven skin. In patients with ethnic skin (ie, skin of color), energy devices are used more cautiously to avoid adverse events. The most common and concerning adverse event is postinflammatory hyperpigmentation. Lower fluence, longer pulse durations, and careful device selection can mitigate the risk of scarring and pigmentary abnormality...
December 2016: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/27918003/combination-therapy-in-skin-of-color-including-injectables-laser-and-light-devices
#13
Lark Guss, Joanna G Bolton, Sabrina Guillen Fabi
With the rapid increase in patients seeking cosmetic treatments, the variation in responses of lightly pigmented skin versus darkly pigmented skin has become increasingly apparent. Despite extensive treatment options in patients with skin of color, there is a paucity of well-designed studies performed on this patient population. The lack of research is concerning, as it is well documented that patients with darker skin types are at an increased risk of adverse events when treated with many of the available modalities used in cosmetic procedures...
December 2016: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/27917779/low-pressure-sequential-compression-of-lower-limbs-enhances-forearm-skin-blood-flow
#14
Guy Amah, Sebastian Voicu, Philippe Bonnin, Nathalie Kubis
PURPOSE: We investigated whether forearm skin blood flow could be improved when a multilayer pulsatile inflatable suit was applied at a low pressure to the lower limbs and abdomen. We hypothesized that a non-invasive purely mechanical stimulation of the lower limbs could induce remote forearm blood flow modifications. METHODS: The pulsatile suit induced a sequential compartmentalized low compression (65 mmHg), which was synchronized with each diastole of the cardiac cycle with each phase evolving centripetally (lower limbs to abdomen)...
December 1, 2016: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
https://www.readbyqxmd.com/read/27914995/transdermal-skin-patch-based-on-reduced-graphene-oxide-a-new-approach-for-photothermal-triggered-permeation-of-ondansetron-across-porcine-skin
#15
Florina Teodorescu, Gurvan Quéniat, Catherine Foulon, Marie Lecoeur, Alexandre Barras, Samia Boulahneche, Mohmaed Salah Medjram, Thomas Hubert, Amar Abderrahmani, Rabah Boukherroub, Sabine Szunerits
The development of a skin-mounted patch capable of controlled transcutaneous delivery of therapeutics through thermal activation provides a unique solution for the controlled release of active principles over long-term periods. Here, we report on a flexible transdermal patch for photothermal triggered release of ondansetron (ODS), a commonly used drug for the treatment of chemotherapy-induced nausea and vomiting and used as model compound here. To achieve this, a dispersion of ODS-loaded reduced graphene oxide (rGO-ODS) nanosheets were deposited onto Kapton to produce a flexible polyimide-based patch...
November 30, 2016: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/27913970/radiological-and-biochemical-effects-ctx-ii-mmp-3-8-and-13-of-low-level-laser-therapy-lllt-in-chronic-osteoarthritis-in-al-kharj-saudi-arabia
#16
Gopal Nambi S, Walid Kamal, Julie George, Elbagir Manssor
Inflammation of synovial membrane and degeneration of articular cartilage in osteoarthritis (OA) lead to major changes in joint space width (JSW) and biochemical components such as collagen-II telopeptide (CTX-II) and matrix metallo protineases (MMP-3, 8, and 13). Low-level laser therapy (LLLT) is thought to have an analgesic effect as well as biomodulatory effect on microcirculation and cartilage regeneration in animal studies. The objective of this study was to examine the analgesic and biochemical effect of LLLT in patients with knee osteoarthritis...
December 3, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27911144/comparison-of-pulsed-dye-laser-versus-combined-pulsed-dye-laser-and-nd-yag-laser-in-the-treatment-of-inflammatory-acne-vulgaris
#17
Manal Mohamed Salah El Din, Nevien Ahmed Samy, Amira Eid Salem
BACKGROUND: Both pulsed dye laser and combined 585/1,064-nm (sequential dual-wave-length PDL and Nd:YAG) laser improves inflammatory skin disorders including acne vulgaris. OBJECTIVE: To compare the efficacy of 585 nm pulsed dye laser versus sequential dual-wave-length PDL and Nd:YAG in treatment of acne vulgaris. PATIENTS AND METHOD: Thirty patients complaining of acne vulgaris were treated with a single pass of PDL alone on half of the face and a single pass of combined 585/1064-nm laser on the other half for four treatment sessions at 2 weeks interval, then assessed by the count and severity of the acne lesions & digital camera photographs Results: The study showed that inflammatory acne lesions count was significantly reduced by 82...
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27911117/are-lasers-superior-to-lights-in-the-photoepilation-of-fitzpatrick-v-and-vi-skin-types-a-comparison-between-nd-yag-laser-and-intense-pulsed-light
#18
Bibilash Bs, Ravi Kumar Chittoria, Devinder Mohan Thappa, Devi Prasad Mohapatra, Friji M T, Dineshkumar S, Sandhya Pandey
BACKGROUND AND OBJECTIVES: There are no large volume comparative studies available to compare the efficacy of lasers over lights for hair removal in Fitzpatrick V and VI skin types. This study is designed to compare the efficacy of Nd:YAG Laser versus IPL in the darker skin types. STUDY DESIGN/MATERIALS AND METHODS: Thirty nine patients included in Group-1 were treated with Nd:YAG and 31 in group-2 with IPL. Both groups received 5 sessions of treatment. The hair counts were assessed using digital photography and manual counting method before and after treatment and results were analysed...
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27906359/monitoring-blood-vital-bio-signs-using-secondary-speckle-patterns
#19
Talia Sirkis, Yevgeny Beiderman, Sergey Agdarov, Yafim Beiderman, Zeev Zalevsky
Continuous noninvasive measurement of vital bio-signs, such as cardiopulmonary parameters, is an important tool in the evaluation process of the patient's physiological condition and in the health monitoring of the patient. On the demand of new enabling technologies, some works have been done in continuous monitoring of blood pressure and pulse wave velocity. In this paper, we introduce further application of a novel technique for remote noncontact blood pulse wave velocity and pressure measurement based on tracking the temporal changes of reflected secondary speckle patterns produced in human skin when illuminated by a laser beam...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27906358/monitoring-blood-vital-bio-signs-using-secondary-speckle-patterns
#20
Talia Sirkis, Yevgeny Beiderman, Sergey Agdarov, Yafim Beiderman, Zeev Zalevsky
Continuous noninvasive measurement of vital bio-signs, such as cardiopulmonary parameters, is an important tool in the evaluation process of the patient's physiological condition and in the health monitoring of the patient. On the demand of new enabling technologies, some works have been done in continuous monitoring of blood pressure and pulse wave velocity. In this paper, we introduce further application of a novel technique for remote noncontact blood pulse wave velocity and pressure measurement based on tracking the temporal changes of reflected secondary speckle patterns produced in human skin when illuminated by a laser beam...
November 28, 2016: Optics Express
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