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https://www.readbyqxmd.com/read/29382082/validation-of-the-english-version-of-the-14-item-mediterranean-diet-adherence-screener-of-the-predimed-study-in-people-at-high-cardiovascular-risk-in-the-uk
#1
Angeliki Papadaki, Laura Johnson, Zoi Toumpakari, Clare England, Manmita Rai, Stu Toms, Chris Penfold, Itziar Zazpe, Miguel A Martínez-González, Gene Feder
The aim of this study was to examine the validity of the English version of the PREvencion con DIetaMEDiterranea (PREDIMED) 14-item Mediterranean Diet Adherence Screener (MEDAS), a brief questionnaire assessing adherence to the Mediterranean diet (MedDiet), which was used in the PREDIMED trial for assessment and immediate feedback. This instrument (MEDAS) was administered to 96 adults with a high cardiovascular risk (66% women, mean age 68.3 ± 6.0 years), recruited from general practices in Bristol, UK. Participants then completed a 3-day estimated food record, and the MEDAS was administered again one month later...
January 28, 2018: Nutrients
https://www.readbyqxmd.com/read/29366273/the-predimed-score-index-of-adherence-to-the-mediterranean-diet-in-the-general-population-the-plic-study
#2
Clara Visinoni, Laura Redaelli, Cristina Tidone, Katia Garlaschelli, Liliana Grigore, Andrea Baragetti, Giuseppe Danilo Norata, Alberico Luigi Catapano
No abstract text is available yet for this article.
August 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29352655/legume-consumption-and-risk-of-all-cause-cardiovascular-and-cancer-mortality-in-the-predimed-study
#3
Christopher Papandreou, Nerea Becerra-Tomás, Mònica Bulló, Miguel Ángel Martínez-González, Dolores Corella, Ramon Estruch, Emilio Ros, Fernando Arós, Helmut Schroder, Montserrat Fitó, Lluís Serra-Majem, José Lapetra, Miquel Fiol, Miguel Ruiz-Canela, Jose V Sorli, Jordi Salas-Salvadó
BACKGROUND & AIMS: Limited prospective studies have examined the association between legumes consumption and mortality, whereas scarce, if at all, previous studies have evaluated such associations taking into consideration specific grain legumes. We aimed to investigate the association between total legumes consumption and grain legumes species (dry beans, chickpeas, lentils, and fresh peas) with all-cause, cardiovascular disease (CVD), cancer and other-cause mortality among elderly Mediterranean individuals at high CVD risk...
January 9, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29316612/association-between-diet-quality-scores-adiposity-total-cholesterol-and-markers-of-nutritional-status-in-european-adults-findings-from-the-food4me-study
#4
Rosalind Fallaize, Katherine M Livingstone, Carlos Celis-Morales, Anna L Macready, Rodrigo San-Cristobal, Santiago Navas-Carretero, Cyril F M Marsaux, Clare B O'Donovan, Silvia Kolossa, George Moschonis, Marianne C Walsh, Eileen R Gibney, Lorraine Brennan, Jildau Bouwman, Yannis Manios, Miroslaw Jarosz, J Alfredo Martinez, Hannelore Daniel, Wim H M Saris, Thomas E Gundersen, Christian A Drevon, Michael J Gibney, John C Mathers, Julie A Lovegrove
Diet-quality scores (DQS), which are developed across the globe, are used to define adherence to specific eating patterns and have been associated with risk of coronary heart disease and type-II diabetes. We explored the association between five diet-quality scores (Healthy Eating Index, HEI; Alternate Healthy Eating Index, AHEI; MedDietScore, MDS; PREDIMED Mediterranean Diet Score, P-MDS; Dutch Healthy Diet-Index, DHDI) and markers of metabolic health (anthropometry, objective physical activity levels (PAL), and dried blood spot total cholesterol (TC), total carotenoids, and omega-3 index) in the Food4Me cohort, using regression analysis...
January 6, 2018: Nutrients
https://www.readbyqxmd.com/read/29306452/plasma-lipidome-patterns-associated-with-cardiovascular-risk-in-the-predimed-trial-a-case-cohort-study
#5
Cristina Razquin, Liming Liang, Estefanía Toledo, Clary B Clish, Miguel Ruiz-Canela, Yan Zheng, Dong D Wang, Dolores Corella, Olga Castaner, Emilio Ros, Fernando Aros, Enrique Gomez-Gracia, Miquel Fiol, José Manuel Santos-Lozano, Marta Guasch-Ferre, Lluis Serra-Majem, Aleix Sala-Vila, Pilar Buil-Cosiales, Monica Bullo, Montserrat Fito, Olga Portoles, Ramon Estruch, Jordi Salas-Salvado, Frank B Hu, Miguel A Martinez-Gonzalez
BACKGROUND: The study of the plasma lipidome may help to better characterize molecular mechanisms underlying cardiovascular disease. The identification of new lipid biomarkers could provide future targets for prevention and innovative therapeutic approaches. In the frame of the PREDIMED trial, our aim was to examine the associations of baseline lipidome patterns or their changes with the risk of clinical CVD events. METHODS: We included 983 participants in our case-cohort study...
February 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29305130/effects-of-the-ser326cys-polymorphism-in-the-dna-repair-ogg1-gene-on-cancer-cardiovascular-and-all-cause-mortality-in-the-predimed-study-modulation-by-diet
#6
Dolores Corella, Judith B Ramírez-Sabio, Oscar Coltell, Carolina Ortega-Azorín, Ramón Estruch, Miguel A Martínez-González, Jordi Salas-Salvadó, José V Sorlí, Olga Castañer, Fernando Arós, Franscisco J Garcia-Corte, Lluís Serra-Majem, Enrique Gómez-Gracia, Miquel Fiol, Xavier Pintó, Guillermo T Saez, Estefanía Toledo, Josep Basora, Montserrat Fitó, Montserrat Cofán, Emilio Ros, Jose M Ordovas
BACKGROUND: Oxidatively induced DNA damage, an important factor in cancer etiology, is repaired by oxyguanine glycosylase 1 (OGG1). The lower repair capacity genotype (homozygote Cys326Cys) in the OGG1-rs1052133 (Ser326Cys) polymorphism has been associated with cancer risk. However, no information is available in relation to cancer mortality, other causes of death, and modulation by diet. OBJECTIVE: Our aim was to evaluate the association of the OGG1-rs1052133 with total, cancer, and cardiovascular disease (CVD) mortality and to analyze its modulation by the Mediterranean diet, focusing especially on total vegetable intake as one of the main characteristics of this diet...
January 2, 2018: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/29295516/impact-of-consuming-extra-virgin-olive-oil-or-nuts-within-a-mediterranean-diet-on-dna-methylation-in-peripheral-white-blood-cells-within-the-predimed-navarra-randomized-controlled-trial-a-role-for-dietary-lipids
#7
Ana Arpón, Fermín I Milagro, Cristina Razquin, Dolores Corella, Ramón Estruch, Montserrat Fitó, Amelia Marti, Miguel A Martínez-González, Emilio Ros, Jordi Salas-Salvadó, José-Ignacio Riezu-Boj, J Alfredo Martínez
DNA methylation could be reversible and mouldable by environmental factors, such as dietary exposures. The objective was to analyse whether an intervention with two Mediterranean diets, one rich in extra-virgin olive oil (MedDiet + EVOO) and the other one in nuts (MedDiet + nuts), was influencing the methylation status of peripheral white blood cells (PWBCs) genes. A subset of 36 representative individuals were selected within the PREvención con DIeta MEDiterránea (PREDIMED-Navarra) trial, with three intervention groups in high cardiovascular risk volunteers: MedDiet + EVOO, MedDiet + nuts, and a low-fat control group...
December 23, 2017: Nutrients
https://www.readbyqxmd.com/read/29236075/risks-and-benefits-of-increased-nut-consumption-cardiovascular-health-benefits-outweigh-the-burden-of-carcinogenic-effects-attributed-to-aflatoxin-b%C3%A2-exposure
#8
Hanna Eneroth, Stina Wallin, Karin Leander, Johan Nilsson Sommar, Agneta Åkesson
Nuts are rich in nutrients and mounting evidence shows that consumption reduces cardiovascular disease (CVD) incidence. Nuts may also be a major source of aflatoxin B₁, a potent liver carcinogen and the risk/benefit balance is unknown. Based on national statistics and data from the PREDIMED intervention trial, we estimated the potential CVD-reduction if Swedes aged 55-79 consumed 30 g nuts/day, instead of the current national average of five grams per day. We also assessed the reduction in disability-adjusted life years (DALYs) due to myocardial infarction (MI) and stroke...
December 13, 2017: Nutrients
https://www.readbyqxmd.com/read/29099027/the-effects-of-dietary-nutrition-education-on-weight-and-health-biomarkers-in-breast-cancer-survivors
#9
Andrea Braakhuis, Peta Campion, Karen Bishop
Weight gain after breast cancer diagnosis portends a poorer prognosis, and the majority of sufferers appear to gain weight. Metabolic syndrome is a common co-condition with breast cancer. The Mediterranean diet has been used to reduce excess weight, metabolic syndrome, and to improve the inflammatory profile, and therefore may offer the breast cancer survivor specific benefits over and above the currently recommended nutrition guidelines to eat a low fat, healthy diet. The aim of this randomised controlled trial was to investigate whether a Mediterranean (MD) or low-fat diet (LF) reduce weight and general health in survivors of stage 1-3 breast cancer through a six-month, six-session education package to support dietary change...
June 2, 2017: Medical Sciences: Open Access Journal
https://www.readbyqxmd.com/read/29080862/plasma-metabolites-from-choline-pathway-and-risk-of-cardiovascular-disease-in-the-predimed-prevention-with-mediterranean-diet-study
#10
Marta Guasch-Ferré, Frank B Hu, Miguel Ruiz-Canela, Mònica Bulló, Estefanía Toledo, Dong D Wang, Dolores Corella, Enrique Gómez-Gracia, Miquel Fiol, Ramon Estruch, José Lapetra, Montserrat Fitó, Fernando Arós, Lluís Serra-Majem, Emilio Ros, Courtney Dennis, Liming Liang, Clary B Clish, Miguel A Martínez-González, Jordi Salas-Salvadó
BACKGROUND: The relationship between plasma concentrations of betaine and choline metabolism and major cardiovascular disease (CVD) end points remains unclear. We have evaluated the association between metabolites from the choline pathway and risk of incident CVD and the potential modifying effect of Mediterranean diet interventions. METHODS AND RESULTS: We designed a case-cohort study nested within the PREDIMED (Prevention With Mediterranean Diet) trial, including 229 incident CVD cases and 751 randomly selected participants at baseline, followed up for 4...
October 28, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29046405/potato-consumption-does-not-increase-blood-pressure-or-incident-hypertension-in-2-cohorts-of-spanish-adults
#11
Emily A Hu, Miguel A Martínez-González, Jordi Salas-Salvadó, Dolores Corella, Emilio Ros, Montse Fitó, Antonio Garcia-Rodriguez, Ramon Estruch, Fernando Arós, Miquel Fiol, José Lapetra, Lluís Serra-Majem, Xavier Pintó, Miguel Ruiz-Canela, Cristina Razquin, Mònica Bulló, José V Sorlí, Helmut Schröder, Casey M Rebholz, Estefania Toledo
Background: Potatoes have a high glycemic load but also antioxidants, vitamins, and minerals. It is unclear what mechanisms are involved in relation to their effect on blood pressure (BP) and hypertension.Objectives: This study aimed to assess the association between potato consumption, BP changes, and the risk of hypertension in 2 Spanish populations.Methods: Separate analyses were performed in PREDIMED (PREvención con DIeta MEDiterránea), a multicenter nutrition intervention trial of adults aged 55-80 y, and the SUN (Seguimiento Universidad de Navarra) project, a prospective cohort made up of university graduates and educated adults with ages (means ± SDs) of 42...
October 18, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/29035971/dietary-patterns-and-cognition-in-older-persons
#12
Angela M Abbatecola, Marcello Russo, Michelangela Barbieri
PURPOSE OF REVIEW: The current article reviews recently published evidence of the important role that specific dietary patterns may hold on preventing cognitive impairment and dementia over aging. RECENT FINDINGS: Specific dietary patterns attributed to targeting cardiovascular risk factors may protect against the development of mild cognitive impairment (MCI) and dementia, especially Alzheimer's disease. Numerous epidemiological studies have strongly suggested that multinutrient approaches using the Mediterranean diet (Med diet), dietary approach to systolic hypertension (DASH) and the Mediterranean-DASH diet intervention for neurodegenerative delay (MIND) are associated with a lower risk of cognitive impairment, MCI and Alzheimer's disease in older persons...
January 2018: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/28930197/red-blood-cell-eicosapentaenoic-acid-inversely-relates-to-mri-assessed-carotid-plaque-lipid-core-burden-in-elders-at-high-cardiovascular-risk
#13
Núria Bargalló, Rosa Gilabert, Edwin-Saúl Romero-Mamani, Montserrat Cofán, Philip C Calder, Montserrat Fitó, Dolores Corella, Jordi Salas-Salvadó, Miguel Ruiz-Canela, Ramon Estruch, Emilio Ros, Aleix Sala-Vila
Supplemental marine omega-3 eicosapentaenoic acid (EPA) has an anti-atherosclerotic effect. Clinical research on EPA supplied by the regular diet and atherosclerosis is scarce. In the framework of the PREvención con DIeta MEDiterránea (PREDIMED) trial, we conducted a cross-sectional study in 161 older individuals at high vascular risk grouped into different stages of carotid atherosclerosis severity, including those without ultrasound-detected atheroma plaque (n = 38), with plaques <2.0 mm thick (n = 65), and with plaques ≥2...
September 20, 2017: Nutrients
https://www.readbyqxmd.com/read/28878811/serum-metabolites-in-non-alcoholic-fatty-liver-disease-development-or-reversion-a-targeted-metabolomic-approach-within-the-predimed-trial
#14
Christopher Papandreou, Mònica Bullò, Francisco José Tinahones, Miguel Ángel Martínez-González, Dolores Corella, Georgios A Fragkiadakis, José López-Miranda, Ramon Estruch, Montserrat Fitó, Jordi Salas-Salvadó
BACKGROUND: Limited prospective studies have examined changes in non-alcoholic fatty-liver disease (NAFLD) related serum-metabolites and none the effects of NAFLD-reversion. We aimed to evaluate whether perturbations in metabolites indicate predisposition to NAFLD development and to assess the effects of NAFLD reversion on metabolite profiles. METHODS: A targeted liquid-chromatography tandem mass-spectrometry metabolic profiling (n = 453 metabolites) approach was applied, using serum from 45 subjects of the PREDIMED study, at baseline and after a median 3...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28814398/plasma-lipidomic-profiles-and-cardiovascular-events-in-a-randomized-intervention-trial-with-the-mediterranean-diet
#15
RANDOMIZED CONTROLLED TRIAL
Estefanía Toledo, Dong D Wang, Miguel Ruiz-Canela, Clary B Clish, Cristina Razquin, Yan Zheng, Marta Guasch-Ferré, Adela Hruby, Dolores Corella, Enrique Gómez-Gracia, Miquel Fiol, Ramón Estruch, Emilio Ros, José Lapetra, Montserrat Fito, Fernando Aros, Luis Serra-Majem, Liming Liang, Jordi Salas-Salvadó, Frank B Hu, Miguel A Martínez-González
Background: Lipid metabolites may partially explain the inverse association between the Mediterranean diet (MedDiet) and cardiovascular disease (CVD).Objective: We evaluated the associations between 1) lipid species and the risk of CVD (myocardial infarction, stroke, or cardiovascular death); 2) a MedDiet intervention [supplemented with extra virgin olive oil (EVOO) or nuts] and 1-y changes in these molecules; and 3) 1-y changes in lipid species and subsequent CVD.Design: With the use of a case-cohort design, we profiled 202 lipid species at baseline and after 1 y of intervention in the PREDIMED (PREvención con DIeta MEDiterránea) trial in 983 participants [230 cases and a random subcohort of 790 participants (37 overlapping cases)]...
October 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28734553/dietary-inflammatory-index-and-liver-status-in-subjects-with-different-adiposity-levels-within-the-predimed-trial
#16
Irene Cantero, Itziar Abete, Nancy Babio, Fernando Arós, Dolores Corella, Ramón Estruch, Montse Fitó, James R Hebert, M Ángel Martínez-González, Xavier Pintó, M Puy Portillo, Miguel Ruiz-Canela, Nitin Shivappa, Julia Wärnberg, Enrique Gómez-Gracia, J Antoni Tur, Jordi Salas-Salvadó, M Angeles Zulet, J Alfredo Martínez
BACKGROUND & AIMS: To assess the possible association between a validated Dietary Inflammatory Index (DII) and specific dietary components with suitable non-invasive markers of liver status in overweight and obese subjects within the PREDIMED study. METHODS: A cross-sectional study encompassing 794 randomized overweight and obese participants (mean ± SD age: 67.0 ± 5.0 y, 55% females) from the PREDIMED (PREvención con DIeta MEDiterránea) trial was conducted...
July 6, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28706576/adherence-to-the-mediterranean-diet-and-circulating-levels-of-sirtuin-4-in-obese-patients-a-novel-association
#17
Luigi Barrea, Giovanni Tarantino, Carolina Di Somma, Giovanna Muscogiuri, Paolo Emidio Macchia, Andrea Falco, Annamaria Colao, Silvia Savastano
PURPOSE: This study was aimed at evaluating sirtuin 4 (Sirt4) levels in obese individuals, in relation to their adherence to the Mediterranean diet (MD), a healthy dietary pattern characterized by high antioxidant capacity, and markers of visceral fat storage. SUBJECTS/METHODS: Forty-three obese patients (44% males; BMI: 36.7-58.8 kg/m(2)) were consecutively included. PREvención con DIeta MEDiterránea (PREDIMED) and the 7-day food records were used to assess the adherence to MD and dietary pattern, respectively...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28684083/the-predimed-trial-mediterranean-diet-and-health-outcomes-how-strong-is-the-evidence
#18
RANDOMIZED CONTROLLED TRIAL
M Guasch-Ferré, J Salas-Salvadó, E Ros, R Estruch, D Corella, M Fitó, M A Martínez-González
AIMS: To address potential controversies on the health benefits of the Mediterranean diet (MedDiet) after PREDIMED, a randomized trial of MedDiet for primary cardiovascular prevention. We have focused on: a) the PREDIMED study design, b) analysis of PREDIMED data and c) interpretation of its results. DATA SYNTHESIS: Regarding the design of the trial, its early termination and between-group differences in the intensity of the intervention are potential causes of concern...
July 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28572403/erratum-for-yu-et-al-increases-in-plasma-tryptophan-are-inversely-associated-with-incident-cardiovascular-disease-in-the-prevenci%C3%A3-n-con-dieta-mediterr%C3%A3-nea-predimed-study-j-nutr-2017-147-314-22
#19
https://www.readbyqxmd.com/read/28521737/validation-of-the-german-version-of-the-mediterranean-diet-adherence-screener-medas-questionnaire
#20
Katrin Hebestreit, Maryam Yahiaoui-Doktor, Christoph Engel, Walter Vetter, Michael Siniatchkin, Nicole Erickson, Martin Halle, Marion Kiechle, Stephan C Bischoff
BACKGROUND: Health benefits of the Mediterranean Diet (MD) have been shown in different at-risk populations. A German translation of the Mediterranean Diet Adherence Screener (MEDAS) from the PREvención con DIeta MEDiterránea (PREDIMED) consortium was used in the LIBRE study, investigating effects of lifestyle-intervention on women with BRCA1/2 mutations. The purpose of the present study is to validate the MEDAS German version. METHODS: LIBRE is a multicentre (three university hospitals during this pilot phase), unblinded, randomized, controlled clinical trial...
May 18, 2017: BMC Cancer
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