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JOURNAL ARTICLE
Laura Álvarez-Álvarez, María Rubín-García, Facundo Vitelli-Storelli, Silvia García, Cristina Bouzas, Miguel Ángel Martínez-González, Dolores Corella, Jordi Salas-Salvadó, Mireia Malcampo, J Alfredo Martínez, Ángel M Alonso-Gómez, Julia Wärnberg, Jesús Vioque, Dora Romaguera, José López-Miranda, Ramon Estruch, Francisco J Tinahones, José Lapetra, Lluís Serra-Majem, Aurora Bueno-Cavanillas, Camino García Fernández, Xavier Pintó, Miguel Delgado-Rodríguez, Pilar Matía-Martín, Josep Vidal, Clotilde Vázquez, Lidia Daimiel, Emilio Ros, Ana García-Arellano, María Ángeles Martínez, José V Sorlí, María Dolores Zomeño, Antonio García-Rios, Sandra González-Palacios, Margalida Monserrat-Mesquida, Itziar Abete, Antoni Colom Fernández, Rosa Casas, Naomi Cano Ibañez, Lucía Ugarriza, M Rosa Bernal-López, Maira Bes-Rastrollo, Indira Paz-Graniel, Eva M Asensio, Montse Fitó, Antonio P Arenas Larriva, Alejandro Oncina-Cánovas, Zenaida Vázquez, María Fernández de la Puente, Alejandra Pérez-Vega, Josep A Tur, Vicente Martín-Sánchez
OBJECTIVE: To estimate the environmental impact of a dietary intervention based on an energy-reduced Mediterranean diet (MedDiet) after one year of follow-up. METHODS: Baseline and 1-year follow-up data were used for 5800 participants aged 55-75 years with metabolic syndrome in the PREDIMED-Plus study. Food intake was estimated through a validated semiquantitative food consumption frequency questionnaire, and adherence to the MedDiet was estimated through the Diet Score...
April 18, 2024: Science of the Total Environment
#2
JOURNAL ARTICLE
Linzi Li, Alvaro Alonso, Dora Romaguera, Angel M Alonso-Gómez, Cristina Razquin, Lucas Tojal-Sierra, Miquel Fiol, Miguel Angel Martínez-González, Vinita Subramanya, Jordi Salas-Salvadó, Montserrat Fito, Estefanía Toledo
Background : Lifestyles influence atrial fibrillation (AF) risk. Determining the effect of lifestyle interventions on blood concentrations of biomarkers of AF-related pathways could help understand AF pathophysiology and contribute to AF prevention. Methods : We studied 532 participants enrolled in the PREDIMED-Plus trial, a Spanish randomized trial conducted in adults (55-75 years) with metabolic syndrome and body mass index between 27-40 kg/m2 . Eligible participants were randomized 1:1 to an intensive lifestyle intervention, emphasizing physical activity, weight loss, and adherence to an energy-reduced Mediterranean diet or to a control group...
April 7, 2024: Journal of Clinical Medicine
#3
JOURNAL ARTICLE
Nadine Khoury, María Ángeles Martínez, Stephanie K Nishi, Miguel Ángel Martínez-González, Dolores Corella, Olga Castañer, J Alfredo Martínez, Ángel M Alonso-Gómez, Julia Wärnberg, Jesús Vioque, Dora Romaguera, José López-Miranda, Ramon Estruch, Francisco J Tinahones, José Manuel Santos-Lozano, Lluís Serra-Majem, Aurora Bueno-Cavanillas, Josep A Tur, Sergio Cinza Sanjurjo, Xavier Pintó, José Juan Gaforio, Pilar Matía-Martín, Josep Vidal, Clotilde Vázquez, Lidia Daimiel, Emilio Ros, Carmen Sayon-Orea, Jose V Sorli, Karla-Alejandra Pérez-Vega, Antonio Garcia-Rios, Francisco Ortiz-Díaz, Enrique Gómez-Gracia, M A Zulet, Alice Chaplin, Rosa Casas, Inmaculada Salcedo-Bellido, Lucas Tojal-Sierra, Maria-Rosa Bernal-Lopez, Zenaida Vazquez-Ruiz, Eva M Asensio, Albert Goday, Patricia J Peña-Orihuela, Antonio J Signes-Pastor, Ana Garcia-Arellano, Montse Fitó, Nancy Babio, Jordi Salas-Salvadó
BACKGROUND: Endocrine disruptors (EDs) have emerged as potential contributors to the development of type-2 diabetes. Perfluorooctane sulfonate (PFOS), is one of these EDs linked with chronic diseases and gathered attention due to its widespread in food. OBJECTIVE: To assess at baseline and after 1-year of follow-up associations between estimated dietary intake (DI) of PFOS, and glucose homeostasis parameters and body-mass-index (BMI) in a senior population of 4600 non-diabetic participants from the PREDIMED-plus study...
March 15, 2024: Environment International
#4
JOURNAL ARTICLE
Aniqa B Alam, Estefania Toledo-Atucha, Dora Romaguera, Angel M Alonso-Gómez, Miguel A Martínez-Gonzalez, Lucas Tojal-Sierra, Marta Noris Mora, Caterina Mas-Llado, Linzi Li, Ines Gonzalez-Casanova, Jordi Salas-Salvadó, Montserrat Fitó, Alvaro Alonso
BACKGROUND: Excessive alcohol consumption has been associated with increased risk of atrial fibrillation, although the underlying mechanisms remain unclear. An enlarged left atrium and impaired left atrial function may lead to atrial fibrillation. The association of alcohol consumption with structural and functional left atrial measures, however, has received limited attention. METHODS AND RESULTS: We studied 503 participants from the PREDIMED-Plus (Prevención con Dieta Mediterránea) trial, a randomized trial testing intensive weight loss intervention with an energy-reduced Mediterranean diet and physical activity promotion in preventing cardiovascular disease in adults with metabolic syndrome...
March 27, 2024: Journal of the American Heart Association
#5
JOURNAL ARTICLE
L Álvarez-Álvarez, F Vitelli-Storelli, M Rubín-García, S García, C Bouzas, M Ruíz-Canela, D Corella, J Salas-Salvadó, M Fitó, J A Martínez, L Tojal-Sierra, J Wärnberg, J Vioque, D Romaguera, J López-Miranda, R Estruch, F J Tinahones, J M Santos-Lozano, L Serra-Majem, A Bueno-Cavanillas, C García-Fernández, V Esteve-Luque, M Delgado-Rodríguez, M Torrego-Ellacuría, J Vidal, L Prieto, L Daimiel, R Casas, A García Arellano, S Shyam, J I González, O Castañer, A García-Rios, F Ortiz Díaz, A C Fernández, A Sánchez-Villegas, M Morey, N Cano-Ibañez, C Sorto-Sánchez, M R Bernal-López, M Bes-Rastrollo, S K Nishi, O Coltell, M D Zomeño, P J Peña-Orihuela, D V Aparicio, M A Zulet, Z Vázquez, N Babio, K A Pérez, J A Tur, V Martín-Sánchez
OBJECTIVE: This article aims to estimate the differences in environmental impact (greenhouse gas [GHG] emissions, land use, energy used, acidification and potential eutrophication) after one year of promoting a Mediterranean diet (MD). METHODS: Baseline and 1-year follow-up data from 5800 participants in the PREDIMED-Plus study were used. Each participant's food intake was estimated using validated semi-quantitative food frequency questionnaires, and the adherence to MD using the Dietary Score...
March 12, 2024: Public Health
#6
JOURNAL ARTICLE
Silvia García, Margalida Monserrat-Mesquida, Emma Argelich, Lucía Ugarriza, Jordi Salas-Salvadó, Inmaculada Bautista, Jesús Vioque, María Dolores Zomeño, Dolores Corella, Xavier Pintó, Aurora Bueno-Cavanillas, Lidia Daimiel, J Alfredo Martínez, Stephanie Nishi, Estefanía Herrera-Ramos, Sandra González-Palacios, Montserrat Fitó, Eva M Asensio, Marta Fanlo-Maresma, Naomi Cano-Ibáñez, Esther Cuadrado-Soto, Itziar Abete, Josep A Tur, Cristina Bouzas
Beverages are an important part of the diet, but their environmental impact has been scarcely assessed. The aim of this study was to assess how changes in beverage consumption over a one-year period can impact the environmental sustainability of the diet. This is a one-year longitudinal study of 55-75-year-old participants with metabolic syndrome (n = 1122) within the frame of the PREDIMED-Plus study. Food and beverage intake were assessed using a validated food frequency questionnaire and a validated beverage-specific questionnaire...
March 3, 2024: Nutrients
#7
REVIEW
Sneha Annie Sebastian, Inderbir Padda, Gurpreet Johal
BACKGROUND: Dietary modification plays a pivotal role in the prevention of cardiovascular disease (CVD), with particular emphasis on the potential benefits associated with adopting a Mediterranean diet (MedDiet). Numerous observational studies have explored the impact of the MedDiet on CVD prevention, addressing both primary and secondary prevention. However, a substantial portion of the primary evidence comes from specific Randomized Controlled Trials (RCTs), such as the Lyon Diet Heart Study, the Indo-Mediterranean Diet Heart Study, the PREDIMED Study, and the recent CORDIOPREV Study...
March 1, 2024: Current Problems in Cardiology
#8
JOURNAL ARTICLE
Tonet Serés-Noriega, Clara Viñals, Verónica Perea, Alex Mesa, Laura Boswell, Karla Mariaca, Jesús Blanco, Irene Vinagre, Adriana Pané, Camila Milad, Clara Solà, Enric Esmatjes, Ignacio Conget, Marga Giménez, Antonio J Amor
AIMS: People with type 1 diabetes (T1D) have an increased risk of cardiovascular disease (CVD). The Mediterranean diet is associated with reduced CVD; however, the evidence in T1D is scarce. We aimed to analyse the relationships between adherence to the energy-restricted Mediterranean diet (erMEDd) and carotid atherosclerosis. MATERIALS AND METHODS: We included children with T1D without CVD, with ≥1 of the following: age ≥40 years, diabetic kidney disease, or ≥10 years of disease duration with another risk factor...
March 2024: Diabetes/metabolism Research and Reviews
#9
JOURNAL ARTICLE
Amelie Kurnikowski, Benedetta Salvatori, Michael Krebs, Klemens Budde, Kathrin Eller, Julio Pascual, Micaela Morettini, Christian Göbl, Manfred Hecking, Andrea Tura
Posttransplant diabetes mellitus (PTDM) is a common complication after kidney transplantation. Pathophysiologically, whether beta-cell dysfunction rather than insulin resistance may be the predominant defect in PTDM has been a matter of debate. The aim of the present analysis was to compare glucometabolism in kidney transplant recipients with and without PTDM. To this aim, we included 191 patients from a randomized controlled trial who underwent oral glucose tolerance tests (OGTTs) 6 months after transplantation...
January 30, 2024: Biomedicines
#10
JOURNAL ARTICLE
Inés Domínguez López, Camila Arancibia-Riveros, Rosa Casas, Polina Galkina, Maria Pérez, Miguel Ángel Martínez-González, Montserrat Fitó, Emilio Ros, Ramon Estruch, Rosa M Lamuela-Raventós
OBJECTIVES: Several studies suggest that moderate wine consumption, particularly red wine, may have benefits for cardiovascular health. Red wine contains a variety of bioactive compounds, including polyphenols like phenolic acids, which have demonstrated anti-inflammatory effects in experimental models. The aim of this study was to assess the anti-inflammatory properties of wine, measured as urinary tartaric acid, a new biomarker of wine consumption. DESIGN, SETTINGS, AND PARTICIPANTS: One-year longitudinal study that included 217 participants from the PREDIMED trial...
February 2024: Journal of Nutrition, Health & Aging
#11
REVIEW
Miguel Á Martínez-González, Aitor Hernández Hernández
The Mediterranean diet is the best evidence-based model for cardiovascular prevention. In addition to 2 major randomized secondary prevention trials (Lyon Heart and CORDIOPREV) and 1 primary prevention trial (PREDIMED) that have demonstrated these benefits, there is an unprecedented body of high-quality prospective epidemiological evidence supporting these beneficial effects. The key elements of this traditional pattern are the abundant use of extra-virgin olive oil and high consumption of foods of natural plant-based origin (fruits, vegetables, nuts, and legumes) and fish, along with a reduction in processed meats, red meats, and ultraprocessed products...
February 7, 2024: Revista Española de Cardiología
#12
JOURNAL ARTICLE
Beatriz Candás-Estébanez, Bárbara Fernández-Cidón, Emili Corbella, Cristian Tebé, Marta Fanlo-Maresma, Virginia Esteve-Luque, Jordi Salas-Salvadó, Montserrat Fitó, Antoni Riera-Mestre, Emilio Ros, Xavier Pintó
Metabolic syndrome (MetS) is associated with alterations of lipoprotein structure and function that can be characterized with advanced lipoprotein testing (ADLT). The effect of the Mediterranean diet (MedDiet) and weight loss on the lipoprotein subclass profile has been scarcely studied. Within the PREDIMED-Plus randomized controlled trial, a sub-study conducted at Bellvitge Hospital recruiting center evaluated the effects of a weight loss program based on an energy-reduced MedDiet (er-MedDiet) and physical activity (PA) promotion (intervention group) compared with energy-unrestricted MedDiet recommendations (control group) on ADLT-assessed lipoprotein subclasses...
January 22, 2024: International Journal of Molecular Sciences
#13
JOURNAL ARTICLE
Ismael García-Campanario, María Jesús Viñolo Gil, Luc E Vanlinthout, Carlos Pérez Pérez, Cristina O'Ferrall González
The COVID-19 pandemic was an unprecedented situation that raised concerns about the physical and mental health of adolescents. Several surveys demonstrated that post-lockdown, women reported more complaints and lower perceived quality of life compared to men. The aim of this study was to analyze gender differences in self-reported physical and mental health immediately after the second lock-down restrictions (July 2020 to December 2020) were suspended and physical exercise classes resumed after a break of several months...
January 12, 2024: Healthcare (Basel, Switzerland)
#14
JOURNAL ARTICLE
Daniel Sanz-Martín, Félix Zurita-Ortega, Eduardo Melguizo-Ibáñez, José Manuel Alonso-Vargas, Rafael Caracuel-Cáliz, José Luis Ubago-Jiménez
Student lifestyles change during university. This research aimed to classify university students according to their levels of physical activity, alcohol consumption, adherence to the Mediterranean diet, and anxiety and studied the relationships between the variables using a multigroup equation model according to gender. The sample was composed of 549 participants (M = 23.06; S.D. = 6.22), of whom 409 were women and 140 were men. Validated and adapted instruments such as the Beck Anxiety Inventory, the PREDIMED Questionnaire, and the Alcohol Use Disorder Identification Test were used...
December 25, 2023: European journal of investigation in health, psychology and education
#15
JOURNAL ARTICLE
Hernando J Margara-Escudero, Indira Paz-Graniel, Jesús García-Gavilán, Miguel Ruiz-Canela, Qi Sun, Clary B Clish, Estefania Toledo, Dolores Corella, Ramón Estruch, Emilio Ros, Olga Castañer, Fernando Arós, Miquel Fiol, Marta Guasch-Ferré, José Lapetra, Cristina Razquin, Courtney Dennis, Amy Deik, Jun Li, Enrique Gómez-Gracia, Nancy Babio, Miguel A Martínez-González, Frank B Hu, Jordi Salas-Salvadó
BACKGROUND: Legume consumption has been linked to a reduced risk of type 2 diabetes (T2D) and cardiovascular disease (CVD), while the potential association between plasma metabolites associated with legume consumption and the risk of cardiometabolic diseases has never been explored. Therefore, we aimed to identify a metabolite signature of legume consumption, and subsequently investigate its potential association with the incidence of T2D and CVD. METHODS: The current cross-sectional and longitudinal analysis was conducted in 1833 PREDIMED study participants (mean age 67 years, 57...
January 20, 2024: Cardiovascular Diabetology
#16
JOURNAL ARTICLE
I Baenas, L Camacho-Barcia, R Granero, C Razquin, D Corella, C Gómez-Martínez, O Castañer-Niño, J A Martínez, Á M Alonso-Gómez, J Wärnberg, J Vioque, D Romaguera, J López-Miranda, R Estruch, F J Tinahones, J Lapetra, J L Serra-Majem, N Cano-Ibáñez, J A Tur, V Martín-Sánchez, X Pintó, J J Gaforio, P Matía-Martín, J Vidal, C Vázquez, L Daimiel, E Ros, S Jiménez-Murcia, S Dalsgaard, A Garcia-Arellano, N Babio, J V Sorli, C Lassale, M García-de-la-Hera, E Gómez-García, M A Zulet, J Konieczna, S Martín-Peláez, L Tojal-Sierra, F J Basterra-Gortari, S de Las Heras-Delgado, O Portoles, M Á Muñoz-Pérez, A P Arenas-Larriva, L Compañ-Gabucio, S Eguaras, S Shyam, M Fitó, R M Baños, J Salas-Salvadó, F Fernández-Aranda
OBJECTIVES: To examine the cross-sectional association between baseline depressive symptoms and the presence of type 2 diabetes (T2D), and its association with glycated hemoglobin (HbA1c) and other metabolic variables, and the prospective association of depressive symptoms and HbA1c after 1 year of follow-up. METHODS: n = 6224 Mediterranean older adults with overweight/obesity and metabolic syndrome (48% females, mean age 64.9 ± 4...
January 13, 2024: Journal of Endocrinological Investigation
#17
JOURNAL ARTICLE
Luigi Barrea, Ludovica Verde, Rosario Suárez, Evelyn Frias-Toral, Celina Andrade Vásquez, Annamaria Colao, Silvia Savastano, Giovanna Muscogiuri
BACKGROUND: Mediterranean Diet (MD) has many health benefits, particularly in reducing cardiovascular risk (CVR). However, it is still little known if there are any sex differences in following this nutritional pattern and, thus, the potential sex-related repercussions on CVR in obesity. The study aimed to characterize sex-related adherence to MD and its association with CVR factors in subjects with obesity. METHODS: A total of 968 females (33.81 ± 11...
January 10, 2024: Journal of Translational Medicine
#18
REVIEW
Miguel A Martínez-González
Moderate alcohol intake (or, more specifically, red wine) represents one of the postulated beneficial components of the traditional Mediterranean diet. Many well-conducted nonrandomized studies have reported that light-to-moderate alcohol intake is not only associated with reduced risk of cardiovascular disease, but also of all-cause mortality. Nonetheless, alcohol is an addictive substance imposing huge threats for public health. Alcohol consumption is associated with increased risks of cancer, neurological harms, injuries, and other adverse outcomes...
December 28, 2023: American Journal of Clinical Nutrition
#19
RANDOMIZED CONTROLLED TRIAL
S Shyam, J F García-Gavilán, I Paz-Graniel, J J Gaforio, M Á Martínez-González, D Corella, J A Martínez, Á M Alonso-Gómez, J Wärnberg, J Vioque, D Romaguera, J López-Miranda, R Estruch, F J Tinahones, J Lapetra, J L Serra-Majem, A Bueno-Cavanillas, J A Tur, V Martín Sánchez, X Pintó, P Matía-Martín, J Vidal, M Del Mar Alcarria, L Daimiel, E Ros, F Fernandez-Aranda, S K Nishi, Ó García-Regata, R Perez Araluce, E M Asensio, O Castañer, A Garcia-Rios, A Oncina-Cánovas, C Bouzas, M A Zulet, E Rayó, R Casas, S Martin-Pelaez, L Tojal-Sierra, M R Bernal-López, S Carlos, J V Sorlí, A Goday, P J Peña-Orihuela, A Pastor-Morel, S Eguaras, M D Zomeño, M Delgado-Rodríguez, N Babio, M Fitó, J Salas-Salvadó
OBJECTIVES: We tested the effects of a weight-loss intervention encouraging energy-reduced MedDiet and physical activity (PA) in comparison to ad libitum MedDiet on COVID-19 incidence in older adults. DESIGN: Secondary analysis of PREDIMED-Plus, a prospective, ongoing, multicentre randomized controlled trial. SETTING: Community-dwelling, free-living participants in PREDIMED-Plus trial. PARTICIPANTS: 6,874 Spanish older adults (55-75 years, 49% women) with overweight/obesity and metabolic syndrome...
2023: Journal of Nutrition, Health & Aging
#20
JOURNAL ARTICLE
Margalida Monserrat-Mesquida, Cristina Bouzas, Silvia García, Maria Magdalena Quetglas-Llabrés, David Mateos, Lucía Ugarriza, Cristina Gómez, Antoni Sureda, Josep A Tur
BACKGROUND: Carbon dioxide (CO2 ) is a primary greenhouse gas (GHG) causing global temperature to rise. Unsustainable diets induce an increment in the risk of obesity and noncommunicable diseases but also contribute to the global GSG burden. OBJECTIVE: To assess whether CO2 dietary emissions influence the inflammatory and oxidative status of subjects with metabolic syndrome (MetS). METHODS: As part of the PREDIMED-Plus study, 100 adults (55-75 years old) from the Balearic Islands, Spain, were recruited and classified according to their dietary CO2 emissions...
December 8, 2023: Nutrients
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