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https://www.readbyqxmd.com/read/29336147/urolithins-attenuate-lps-induced-neuroinflammation-in-bv2microglia-via-mapk-akt-and-nf-%C3%AE%C2%BAb-signaling-pathways
#1
Jialin Xu, Chunhui Yuan, Guihua Wang, Jiaming Luo, Hang Ma, Li Xu, Yu Mu, Yuanyuan Li, Navindra P Seeram, Xueshi Huang, Liya Li
Emerging data suggest that urolithins, gut microbiota metabolites of ellagitannins, contribute toward multiple health benefits attributed to ellagitannin-rich foods, including walnuts, red raspberry, strawberry, and pomegranate. However, there is limited data on whether the potential neuroprotective effects of these ellagitannin-rich foods are mediated by urolithins. Herein, we evaluated the potential mechanisms of antineuroinflammatory effects of urolithins (urolithins A, B, and C; 8-methyl-O-urolithin A; and 8,9-dimethyl-O-urolithin C) in BV2 murine microglia in vitro...
January 16, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29335694/the-seventh-biennial-berry-health-benefits-symposium
#2
EDITORIAL
Navindra P Seeram, Britt Burton-Freeman
Research advancing current scientific understanding of the health benefits of berries continues to increase. The Berry Health Benefits Symposium (BHBS) is a biennial meeting highlighting the most recent berry health benefits research from all over the world. Pismo Beach, California was the venue for the seventh biennial BHBS in 2017, and featured oral invited papers on heart health and healthy aging, gut/microbiome health, brain aging, inflammation, cancer prevention, berry special topics, technology and chemistry...
January 16, 2018: Food & Function
https://www.readbyqxmd.com/read/29329839/bioaccessibility-and-potential-bioavailability-of-phenolic-compounds-from-achenes-as-a-new-target-for-strawberry-breeding-programs
#3
María Teresa Ariza, Patricia Reboredo-Rodríguez, Lucía Cervantes, Carmen Soria, Elsa Martínez-Ferri, Carmen González-Barreiro, Beatriz Cancho-Grande, Maurizio Battino, Jesús Simal-Gándara
Strawberry is a major natural source of bioactive compounds. Botanically, strawberry is an aggregate fruit consisting of a fleshy floral receptacle that bears a cluster of real dry fruits (achenes). Existing knowledge on the phenolic composition of achenes and its contribution to that of the whole fruit is limited. Also, the gastric and intestinal bioavailability of phenols is poorly known. In this work, a combination of spectrophotometric and HPLC-DAD methods was used to analyse the phenolic composition of whole fruits and achenes before and after in vitro digestion...
May 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29324257/effects-of-pelargonidin-3-o-glucoside-and-its-metabolites-on-lipopolysaccharide-stimulated-cytokine-production-by-thp-1-monocytes-and-macrophages
#4
Anna M Amini, Jeremy P E Spencer, Parveen Yaqoob
Epidemiological evidence suggests cardioprotective effects of anthocyanin consumption. This study examined the predominant strawberry anthocyanin, pelargonidin-3-O-glucoside (Pg-3-glc), and three of its plasma metabolites (protocatechuic acid [PCA], 4-hydroxybenzoic acid, and phloroglucinaldehyde [PGA]) for effects on the production of selected cytokines by lipopolysaccharide-stimulated THP-1 monocytes and macrophages. Concentrations of tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6, IL-8 and IL-10 were determined using a cytometric bead array kit...
January 8, 2018: Cytokine
https://www.readbyqxmd.com/read/29318244/metabolic-fate-of-strawberry-polyphenols-after-chronic-intake-in-healthy-older-adults
#5
Amandeep K Sandhu, Marshall G Miller, Nopporn Thangthaeng, Tammy M Scott, Barbara Shukitt-Hale, Indika Edirisinghe, Britt Burton-Freeman
Strawberries contain a wide array of nutrients and phytochemicals including polyphenols such as anthocyanins, proanthocyanidins and ellagitannins. These polyphenols are absorbed and metabolized to various phenolic metabolites/conjugates in the body, which may play a role in disease risk reduction. In the present study, we investigated the metabolic fate of strawberry polyphenols after chronic (90 days) supplementation of freeze-dried strawberry (24 g d-1, equivalent to 2 cups of fresh strawberries) vs. control powder in 19 healthy older adults...
January 10, 2018: Food & Function
https://www.readbyqxmd.com/read/29306187/the-ellagitannin-het-induces-electrolyte-leakage-calcium-influx-and-the-accumulation-of-nitric-oxide-and-hydrogen-peroxide-in-strawberry
#6
Gustavo Gabriel Martos, Alicia Mamaní, María Paula Filippone, Atilio Pedro Castagnaro, Juan Carlos Díaz Ricci
HeT (1-0-galloyl-2,3; 4,6-bis-hexahydroxydiphenoyl-β-D-glucopyranose) is a penta-esterified ellagitannin obtained from strawberry leaves. Previous studies have shown that foliar application of HeT prior to inoculation with a virulent pathogen increases the resistance toward Colletotrichum acutatum in strawberry plants and to Xanthomonas citri subsp. citri in lemon plants. In this work we report that HeT induces an immediate leak of electrolytes, the hyperpolarization of the cellular membrane, a rapid Ca2+ influx to the cytoplasm during the first few seconds, which in turn modulates the accumulation of nitric oxide 5 min after treatment...
December 27, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29299233/mating-status-correlates-with-dorsal-brightness-in-some-but-not-all-poison-frog-populations
#7
Corinna E Dreher, Ariel Rodríguez, Molly E Cummings, Heike Pröhl
Sexual signals are important for intraspecific communication and mate selection, but their evolution may be driven by both natural and sexual selection, and stochastic processes. Strawberry poison frogs (Oophaga pumilio) show strong color divergence among populations, but coloration also varies among individuals of the same population. The importance of coloration for female mate choice has been studied intensely, and sexual selection seems to affect color divergence in strawberry poison frogs. However, the effect of coloration on mating success under field conditions has received very little attention...
December 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29298111/colonization-and-movement-of-xanthomonas-fragariae-in-strawberry-tissues
#8
Hehe Wang, Christine McTavish, William W Turechek
Xanthomonas fragariae causes angular leaf spot of strawberry, an important disease in strawberry growing regions worldwide. To better understand how X. fragariae multiplies and moves in strawberry plants, a GFP-labelled strain was constructed and used to monitor the pathogen's presence in leaf, petiole, and crown tissue with fluorescence microscopy following natural and wound inoculation in three strawberry cultivars. Taqman PCR was used to quantify bacterial densities in these same tissues regardless of the presence of GFP signal...
January 3, 2018: Phytopathology
https://www.readbyqxmd.com/read/29297940/oral-mucosa-lesions-and-gingival-bleeding-can-indicate-the-progression-of-liver-disease-in-children-and-adolescents-aged-two-to-18-years
#9
Dorota Olczak-Kowalczyk, Ewa Krasuska-Sławińska, Dariusz Gozdowski, Wojciech Kowalczyk, Joanna Pawłowska
AIM: This study assessed correlations between systemic disturbances of paediatric chronic liver diseases (CLD) and oral symptoms in subjects aged 2-18 years. METHODS: It was carried out during outpatient appointments at the Children's Memorial Health Institute, Warsaw, Poland, from 2010-2015 and comprised 52 CLD patients with a mean age of 12.3 ±4.6. We also recruited 54 generally healthy controls with a mean age of 12.0 ±3.7 from the Department of Paediatric Dentistry at the Medical University of Warsaw...
January 3, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29291263/overexpression-of-anthocyanidin-synthase-ans-gene-in-strawberry-enhances-antioxidant-capacity-and-cytotoxic-effects-on-human-hepatic-cancer-cells
#10
Francesca Giampieri, Massimiliano Gasparrini, Tamara Yuliett Forbes-Hernandez, Luca Mazzoni, Franco Capocasa, Silvia Sabbadini, José M Alvarez-Suarez, Sadia Afrin, Carlo Rosati, Tiziana Pandolfini, Barbara Molesini, José F Sanchez-Villa, Iraida Amaya, Bruno Mezzetti, Maurizio Battino
Food fortification through the increase and/or modulation of bioactive compounds has become a major goal for preventing several diseases, including cancer. Here, strawberry lines of cv. Calypso transformed with a construct containing an anthocyanidin synthase (ANS) gene were produced to study the effects on anthocyanin biosynthesis, metabolism and transcriptome. Three strawberry ANS transgenic lines (ANS L5, ANS L15 and ANS L18) were analysed for phytochemical composition and total antioxidant capacity (TAC), and their fruit extracts assessed for cytotoxic effects on hepatocellular carcinoma...
January 1, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29288828/the-effects-of-strawberry-tree-water-leaf-extract-arbutin-and-hydroquinone-on-haematological-parameters-and-levels-of-primary-dna-damage-in-white-blood-cells-of-rats
#11
Karlo Jurica, Irena Brčić Karačonji, Nevenka Kopjar, Ana Shek-Vugrovečki, Tihana Cikač, Vesna Benković
ETHNOPHARMACOLOGICAL RELEVANCE: Strawberry tree (Arbutus unedo L., Ericaceae) leaves represent a potent source of biologically active compounds and have been used for a long to relieve symptoms of various health impairments and diseases. Two major compounds related to their beneficial activities in animals and humans are arbutin and hydroquinone. AIM OF THE STUDY: To establish potential benefit/risk ratio associated with daily oral administration of strawberry tree water leaf extract, arbutin and hydroquinone in doses expected to be non-toxic...
December 27, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29288326/fverga1-encoding-a-della-protein-negatively-regulates-runner-production-in-fragaria-vesca
#12
Weijia Li, Junxiang Zhang, Hongying Sun, Shouming Wang, Keqin Chen, Yuexue Liu, He Li, Yue Ma, Zhihong Zhang
FveRGA1 was highly expressed in tender tissues such as young leaves and stem apices and was localized in the nucleus. RNAi silencing of FveRGA1 in non-runnering woodland strawberry produced many runners. FveRGA1 is thus a key gene controlling strawberry runner formation. The propagation of strawberry is mainly based on runners, while the genes controlling runner production have not been well characterized. Exogenous applications of optimum concentration gibberellins (GAs) promote runner formation in strawberry cultivation and GA can accelerate the degradation of DELLA proteins...
December 29, 2017: Planta
https://www.readbyqxmd.com/read/29287382/the-validated-and-sensitive-hplc-dad-method-for-determination-of-patulin-in-strawberries
#13
Ilona Sadok, Agnieszka Szmagara, Magdalena Maria Staniszewska
This work outlines HPLC coupled with DAD detection for accurate quantification of patulin (mycotoxin) in strawberries. The optimized extraction of fruit samples through the modified QuEChERS technique in acetonitrile acidified with acetic acid (1%, v/v) and citrate-buffered salts followed by dispersive solid phase extraction using a primary secondary amine and graphitized carbon is described. The method presents LOD and LOQ of 1.5 and 5µg/kg, respectively and has been validated in strawberry matrix at three concentration levels (5, 10 and 50µg/kg), according to SANTE/11945/2015 and the 2002/657/EC Decision requirements...
April 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29281111/a-leu-rich-repeat-receptor-like-protein-kinase-faripk1-interacts-with-aba-receptor-faabar-to-regulate-strawberry-fragaria-%C3%A3-ananassa-fruit-ripening
#14
Bing-Zhu Hou, Cheng Xu, Yuan-Yue Shen
Strawberry (Fragaria × ananassa) is a model plant for studying non-climacteric fruit ripening regulated by abscisic acid (ABA), however, its defined molecular mechanisms are yet not fully understood. Here, a strawberry predicted leu-rich repeat (LRR) receptor-like kinase, red-initial protein kinase 1 (FaRIPK1), was screened and shown to interact with a putative ABA receptor, FaABAR, using a yeast two-hybrid assay. This association was confirmed by bimolecular fluorescence complementation and co-immunoprecipitation assays, and shown to occur in the nucleus...
December 21, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29280150/shelf-life-dating-of-shelf-stable-strawberry-juice-based-on-survival-analysis-of-consumer-acceptance-information
#15
Carolien Buvé, Tine Van Bedts, Annelien Haenen, Biniam Kebede, Roel Braekers, Marc Hendrickx, Ann Van Loey, Tara Grauwet
BACKGROUND: Accurate shelf-life dating of food products is crucial for consumers and industries. Therefore, present work applied a science-based approach for shelf-life assessment, including accelerated shelf-life testing (ASLT), acceptability testing and the screening of analytical attributes for fast shelf-life predictions. Shelf-stable strawberry juice was selected as a case study. RESULTS: Ambient storage (20 °C) had no effect on the aroma-based acceptance of strawberry juice...
December 27, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29277255/validation-and-application-of-a-multiresidue-method-based-on-liquid-chromatography-tandem-mass-spectrometry-for-evaluating-the-plant-uptake-of-74-microcontaminants-in-crops-irrigated-with-treated-municipal-wastewater
#16
A B Martínez-Piernas, M I Polo-López, P Fernández-Ibáñez, A Agüera
Reuse of treated wastewater for agricultural purposes can mitigate water stress in some regions where the lack of water is an extended problem. However, the environmental long-term consequences of this practice are still unknown. It is demonstrated that using reclaimed water for irrigation lead to accumulation and translocation of some microcontaminants (MCs) in soil and crops. However, so far, only a small group of contaminants has been investigated. This study aims to develop and validate a simple and efficient multiresidue method based on QuEChERs (Quick, Easy, Cheap, Effective and Rugged) extraction coupled to liquid chromatography tandem mass spectrometry (LC-MS/MS)...
December 15, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29277232/isolation-of-strawberry-anthocyanins-using-high-speed-counter-current-chromatography-and-the-copigmentation-with-catechin-or-epicatechin-by-high-pressure-processing
#17
Hui Zou, Yan Ma, Zhenzhen Xu, Xiaojun Liao, Ailiang Chen, Shuming Yang
Three anthocyanins were isolated from strawberry extract by high-speed counter-current chromatography, using a biphasic mixture of tert-butyl methyl ether, n-butanol, acetonitrile, water and trifluoroacetic acid (2.5:2.0:2.5:5.0:1.0%). The anthocyanins were identified as pelargonidin-3-rutinoside, cyanidin-3-glucoside and pelargonidin-3-glucoside with purity of 95.6%, 96.2% and 99.3% respectively. Additionally, the copigmentation reaction rates between pelargonidin-3-glucoside and phenolic acids (catechin or epicatechin) at pH 1...
May 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29277228/molecular-mechanism-of-action-of-pelargonidin-3-o-glucoside-the-main-anthocyanin-responsible-for-the-anti-inflammatory-effect-of-strawberry-fruits
#18
Larissa Jeremias Duarte, Vitor Clasen Chaves, Marcus Vinicius Pereira Dos Santos Nascimento, Eunice Calvete, Mingchuan Li, Elisa Ciraolo, Alessandra Ghigo, Emilio Hirsch, Claudia Maria Oliveira Simões, Flávio Henrique Reginatto, Eduardo M Dalmarco
Fragaria x ananassa Duch., popularly called strawberry, is known for its worldwide consumption and important biological activities, and these effects are related to its high concentration of anthocyanins. Pelargonidin-3-O-glucoside (P3G) is a major anthocyanin found in strawberry, and was evaluated for its anti-inflammatory action in experimental models. The effect of strawberry extract and P3G, on leukocyte migration, exudation levels and many inflammatory mediators, was therefore evaluated in an in vivo model...
May 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29262412/integrated-karyotyping-of-woodland-strawberry-fragaria-vesca-with-oligopaint-fish-probes
#19
Manman Qu, Kunpeng Li, Yanli Han, Lei Chen, Zongyun Li, Yonghua Han
Chromosome identification is critical for many aspects of cytogenetic research. However, for Fragaria vesca, definite identification of individual chromosomes is almost impossible because of their small size and high similarity. Here, we demonstrate that bulked oligonucleotide (oligo) probes can be used as chromosome-specific DNA markers for chromosome identification in F. vesca. Oligos specific to entire pseudochromosomes in the draft genome of F. vesca were identified and synthesized as libraries. In all, we synthesized 6 oligo libraries corresponding to 6 pseudochromosomes of F...
December 21, 2017: Cytogenetic and Genome Research
https://www.readbyqxmd.com/read/29259594/evaluation-of-sanitizing-methods-for-reducing-microbial-contamination-on-fresh-strawberry-cherry-tomato-and-red-bayberry
#20
Wei Wei, Xu Wang, Zhongwen Xie, Wen Wang, Junfeng Xu, Yuanjing Liu, Haiyan Gao, Yu Zhou
Strawberries, cherry tomatoes, and red bayberries, which are the most popular types of fresh produce in China, are vulnerable to microbial contamination. In this study, different sanitizing methods [treatment with 2% organic acids, 0.02% sodium hypochlorite (SH), 0.1% sodium chlorite (SC), and 0.1% acidified sodium chlorite (ASC)] were applied to fresh strawberry, cherry tomato, and red bayberry, and their abilities to reduce aerobic bacteria, Escherichia coli O157:H7, mold, yeast, and Salmonella Typhimurium were evaluated...
2017: Frontiers in Microbiology
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