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https://www.readbyqxmd.com/read/28453514/gut-check-the-evolution-of-an-educational-board-game
#1
David A Coil, Cassandra L Ettinger, Jonathan A Eisen
The "gamification" of science has gained a lot of traction in recent years, and games that convey scientific concepts or themes are increasingly popular. While a number of existing games touch on microbiology, very few consider the beneficial (as opposed to the detrimental) aspects of microbes. We designed a board game called "Gut Check: The Microbiome Game" to fill this gap. The game is meant to be both educational as well as challenging and fun. Here we discuss the development of the game, some of the logistics of game development in this context, and offer suggestions for others thinking of similar projects...
April 2017: PLoS Biology
https://www.readbyqxmd.com/read/28440970/factors-associated-with-cigarette-smoking-in-central-parts-of-iran
#2
Mujtaba Shuja, Nizal Sarrafzadegan, Hamid Reza Roohafza, Masoumeh Sadeghi, Mahin Ghafari, Mahdi Mohammadian, Abdollah Mohammadian Hafshejani
Background: This study aims to assess factors associated with cigarette smoking in central parts of Iran. Materials and methods: We used the data of the post intervention phase of Isfahan Healthy Heart Program (IHHP) that was conducted in 2007. Logistic regression was used for calculating crude and adjusted Odds Ratios (OR). The group with the least prevalence of smoking was considered as the Reference Group (RG) and the OR for other parts of the variable was calculated based on the RG and reported with a confidence interval of 95%...
March 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28439379/injuries-violence-and-bullying-among-middle-school-students-in-oman
#3
Richard P Peyton, Shamika Ranasinghe, Kathryn H Jacobsen
OBJECTIVES: Injuries account for a substantial proportion of the burden of disease in adolescents globally. This paper describes injury rates and associated exposures, and risk behaviors in Oman's 2010 Global School-based Student Health Survey (GSHS). METHODS: This study used complex samples analysis to examine nationally-representative data from 1 606 students in grades eight, nine, and 10 who participated in the 2010 Oman GSHS. RESULTS: In total, 34...
March 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28438419/importance-of-extended-blood-group-genotyping-in-multiply-transfused-patients
#4
Nadila Haryani Osman, Jameela Sathar, Chooi Fun Leong, Noor Fadzilah Zulkifli, Raja Zahratul Azma Raja Sabudin, Ainoon Othman, Asral Wirda Ahmad Asnawi
Blood group antigen systems are not limited to the ABO blood groups. There is increasing interest in the detection of extended blood group systems on the red cell surface. The conventional method used to determine extended blood group antigens or red cell phenotype is by serological testing, which is based on the detection of visible haemagglutination or the presence of haemolysis. However, this technique has many limitations due to recent exposure to donor red cell, certain drugs or medications or other diseases that may alter the red cell membrane...
April 9, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/28434251/a-mock-randomized-controlled-trial-with-audience-response-technology-for-teaching-and-learning-epidemiology
#5
Philip R A Baker, Daniel P Francis, Abby Cathcart
The study's objective was to apply and assess an active learning approach to epidemiology and critical appraisal. Active learning comprised a mock, randomized controlled trial (RCT) conducted with learners in 3 countries. The mock trial consisted of blindly eating red Smarties candy (intervention) compared to yellow Smarties (control) to determine whether red Smarties increase happiness. Audience response devices were employed with the 3-fold purposes to produce outcome data for analysis of the effects of red Smarties, identify baseline and subsequent changes in participant's knowledge and confidence in understanding of RCTs, and assess the teaching approach...
April 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28424217/use-of-life-jackets-and-other-types-of-flotation-for-in-water-recreation-in-designated-swim-areas-in-washington-state
#6
Linda Quan, Thomas Mangione, Elizabeth Bennett, Wendy Chow
Most fatal drownings worldwide occur in open water. Flotation devices may protect swimmers. Their use by those recreating in water has not been described. METHODS: Observational survey of swimmers and waders at designated swim sites at lakes and rivers evaluated them by age group, sex, type of flotation used (life jacket vs substandard flotation, eg, water wings, noodles, inflatables) and, for children <6 years, being within arm's reach of an adult. RESULTS: Of 1967 swimmers/waders observed, 37% used some type of flotation device...
April 19, 2017: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/28420588/comparison-of-an-electronic-versus-traditional-food-diary-for-assessing-dietary-intake-a-validation-study
#7
Nicholas R Fuller, Mackenzie Fong, James Gerofi, Fatima Ferkh, Chloris Leung, Lisa Leung, Shaoyu Zhang, Michael Skilton, Ian D Caterson
BACKGROUND: Paper-based estimated food diaries are often used in research to collect dietary data, despite this method being burdensome for both participants and researchers. Such food diaries are often time consuming, labour intensive, and rely on participant literacy and therefore may lead to greater rates of under-reporting. METHODS: This study assessed the validity of the 'Boden Food Plate', a novel web-based electronic application, compared to a paper-based three-day estimated food diary...
April 15, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28418404/a-pathway-linking-reward-circuitry-impulsive-sensation-seeking-and-risky-decision-making-in-young-adults-identifying-neural-markers-for-new-interventions
#8
H W Chase, J C Fournier, M A Bertocci, T Greenberg, H Aslam, R Stiffler, J Lockovich, S Graur, G Bebko, E E Forbes, M L Phillips
High trait impulsive sensation seeking (ISS) is common in 18-25-year olds, and is associated with risky decision-making and deleterious outcomes. We examined relationships among: activity in reward regions previously associated with ISS during an ISS-relevant context, uncertain reward expectancy (RE), using fMRI; ISS impulsivity and sensation-seeking subcomponents; and risky decision-making in 100, transdiagnostically recruited 18-25-year olds. ISS, anhedonia, anxiety, depression and mania were measured using self-report scales; clinician-administered scales also assessed the latter four...
April 18, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28416247/adaptive-crt-in-patients-with-normal-av-conduction-and-left-bundle-branch-block-does-qrs-duration-matter
#9
Hiro Yamasaki, Daniel Lustgarten, Jeffrey Cerkvenik, David Birnie, Maurizio Gasparini, Kathy Lia-Fun Lee, Yukio Sekiguchi, Niraj Varma, Bernd Lemke, Randall C Starling, Kazutaka Aonuma
BACKGROUND: Adaptive cardiac resynchronization therapy (aCRT) is a dynamic optimization algorithm which paces only the left ventricle (LV) when atrio-ventricular (AV) conduction is normal, thus reducing right ventricular (RV) pacing. However, the impact of QRS duration on aCRT efficacy remains uncertain. We examined whether QRS duration impacts aCRT effectiveness in patients with left bundle branch block (LBBB) and preserved AV conduction. METHODS: Randomized patients in the Adaptive CRT trial, which enrolled NYHA III/IV patients, were used in this analysis...
April 12, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28412835/validation-of-a-seven-factor-structure-for-the-motives-for-playing-drinking-games-measure
#10
Byron L Zamboanga, Shannon Audley, Janine V Olthuis, Heidemarie Blumenthal, Cara C Tomaso, Ngoc Bui, Brian Borsari
Playing drinking games can be characterized as a high-risk drinking activity because games are typically designed to promote heavy alcohol consumption. While research suggests that young adults are motivated to play drinking games for a variety of reasons (e.g., for thrills/fun, for the competition), the Motives for Playing Drinking Games measure has received limited empirical attention. We examined the psychometric properties of this measure with a confirmation sample of young adults recruited from Amazon's MTurk ( N = 1,809, ages 18-25 years, 47% men; 41% not currently enrolled in college) and a validation sample of college students ( N = 671; ages 18-23 years; 26% men)...
April 1, 2017: Assessment
https://www.readbyqxmd.com/read/28411334/normative-values-for-a-tablet-computer-based-application-to-assess-chromatic-contrast-sensitivity
#11
Lakshmi Bodduluri, Mei Ying Boon, Malcolm Ryan, Stephen J Dain
Tablet computer displays are amenable for the development of vision tests in a portable form. Assessing color vision using an easily accessible and portable test may help in the self-monitoring of vision-related changes in ocular/systemic conditions and assist in the early detection of disease processes. Tablet computer-based games were developed with different levels of gamification as a more portable option to assess chromatic contrast sensitivity. Game 1 was designed as a clinical version with no gaming elements...
April 14, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/28402539/associating-resting-state-connectivity-with-trait-impulsivity
#12
Nicholas H Angelides, Jayesh Gupta, Timothy J Vickery
Psychometric research has identified stable traits that predict inter-individual differences in appetitive motivation and approach behavior. Behavioral Inhibition System/Behavioral Activation System (BIS/BAS) scales have been developed to quantitatively assess these traits. However, neural mechanisms corresponding to the proposed constructs reflected in BIS/BAS are still poorly defined. The ventral striatum (VS) and orbitofrontal cortex (OFC) are implicated in subserving reward-related functions that are also associated with the BAS...
April 11, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28392229/impact-of-intravenous-contrast-used-in-computed-tomography-on-radiation-dose-to-carotid-arteries-and-thyroid-in-intensity-modulated-radiation-therapy-planning-for-nasopharyngeal-carcinoma
#13
Victor Ho Fun Lee, Sherry Chor Yi Ng, Dora Lai Wan Kwong, Ka On Lam, To Wai Leung
The aim of this study was to investigate if intravenous contrast injection affected the radiation doses to carotid arteries and thyroid during intensity-modulated radiation therapy (IMRT) planning for nasopharyngeal carcinoma (NPC). Thirty consecutive patients with NPC underwent plain computed tomography (CT) followed by repeated scanning after contrast injection. Carotid arteries (common, external, internal), thyroid, target volumes, and other organs-at-risk (OARs), as well as IMRT planning, were based on contrast-enhanced CT (CE-CT) images...
April 6, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28389855/management-of-rheumatoid-arthritis-in-clinical-practice-using-treat-to-target-strategy-where-do-we-stand-in-the-multi-ethnic-malaysia-population
#14
Bee Eng Tan, Ai Lee Lim, Sow Lai Kan, Chong Hong Lim, Ying Fun Ng, Serene Li Ching Tng, Nur Syakirah Hassin, Losshenee Chandran, Norshahida Abdul Hamid, Yvonne Yin Leng Lee
To evaluate the achievement of treat-to-target (T2T) strategy in rheumatoid arthritis (RA) and identify factors associated with failed treatment target in a public rheumatology center. A cross-sectional study was conducted from June 2015 to February 2016. RA patients with disease duration greater than 2 years and under T2T for over a year were invited to the study. Demographic, clinical data, disease activity score of 28 joints (DAS28), and clinical disease activity index (CDAI) were collected in a single routine clinic visit...
April 7, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28388494/energy-drink-and-alcohol-mixed-energy-drink-use-among-high-school-adolescents-association-with-risk-taking-behavior-social-characteristics
#15
REVIEW
Marco Scalese, Francesca Denoth, Valeria Siciliano, Luca Bastiani, Rodolfo Cotichini, Arianna Cutilli, Sabrina Molinaro
PURPOSE: The aims of the study were to: a) examine the prevalence of energy drink (ED) and alcohol mixed with energy drink (AmED) consumption; b) investigate the relationships between ED and AmED with alcohol, binge drinking and drugs accounting for at risk behaviors among a representative sample of Italian adolescents. METHODS: A representative sample of 30,588 Italian high school students, aged 15-19years, was studied. Binary and multivariate logistic regression analyses were performed to determine the independent association of the potential predictors' characteristics with the ED and AmED drinking during the last year...
March 27, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28372536/hoxa10-and-hoxa11-regulate-the-expression-of-contraction-associated-proteins-and-contribute-to-regionalized-myometrium-phenotypes-in-women
#16
Yinan Li, Haolong Li, Ning Xie, Ruiqi Chen, Ahn Rhi Lee, Donna Slater, Stephen Lye, Xuesen Dong
A relaxed fundus (FUN) and a contracted lower uterine segment (LUS) of human myometrium are required for maintaining pregnancy. How this regional myometrium function is regulated remains unclear. We have previously reported that the homeobox protein A13 (HoxA13) is highly expressed in the LUS and can enhance the expression of contraction-associated proteins (CAPs). Here, we show that in contrast to HoxA13, HoxA10 and HoxA11 genes are expressed at significantly higher levels in myometrium tissues and primary myocytes from the FUN...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28366291/the-power-in-being-together-for-young-adults-who-have-heart-disease-the-photoshoot-experience
#17
Robyn Gallagher, Ellen Potter, Linda Thomson Mangnall, Laila Ladak, Patrick Gallagher, Lis Neubeck
OBJECTIVES: The study aimed to determine perceived motivations and benefits of photoshoot participation for young adults who have heart disease. BACKGROUND: Feeling isolated and different can have lifelong affects on quality of life in heart disease survivors. Photoshoots, where people create a photographic image of themselves, promote positive interpretation of their cardiac illness experience, but participant experiences remain under-investigated. METHODS: Young adult heart disease support group members completing a photoshoot were interviewed and data were thematically analyzed...
March 30, 2017: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/28360025/design-and-implementation-of-a-novel-web-based-e-learning-tool-for-education-of-health-professionals-on-the-antibiotic-vancomycin
#18
Stuart Evan Bond, Shelley P Crowther, Suman Adhikari, Adriana J Chubaty, Ping Yu, Jay P Borchard, Craig Steven Boutlis, Wilfred Winston Yeo, Spiros Miyakis
BACKGROUND: Traditional approaches to health professional education are being challenged by increased clinical demands and decreased available time. Web-based e-learning tools offer a convenient and effective method of delivering education, particularly across multiple health care facilities. The effectiveness of this model for health professional education needs to be explored in context. OBJECTIVES: The study aimed to (1) determine health professionals' experience and knowledge of clinical use of vancomycin, an antibiotic used for treatment of serious infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and (2) describe the design and implementation of a Web-based e-learning tool created to improve knowledge in this area...
March 30, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28350247/the-transgenic-zebrafish-display-fluorescence-reflecting-the-expressional-dynamics-of-dihydrofolate-reductase
#19
Wen-Ni Chang, Wan-Yu Chi, Tseng-Ting Kao, Jen-Ning Tsai, Wangta Liu, Shih-Shin Liang, Chien-Chih Chiu, Bing-Hung Chen, Tzu-Fun Fu
Dihydrofolate reductase (DHFR) reduces folic acid and recycles dihydrofolate generated during dTMP biosynthesis to tetrahydrofolate. DHFR is upregulated in rapidly proliferating cells and hence a favored target of antifolate drug against cancers, autoimmune diseases, and microbial infections. However, increased expression of dhfr contributed to the often emerging drug resistance and impeded the therapeutic efficacy of antifolate drugs. Therefore, comprehensive knowledge on the expressional control of dhfr becomes crucial...
March 28, 2017: Zebrafish
https://www.readbyqxmd.com/read/28342472/-the-room-of-errors-a-fun-learning-tool
#20
Émilie Estival, Justine Sinoquet, Franck Cluzel
Simulation in health care, a source of innovative pedagogical developments, is particularly well-suited to the training of nursing teams. It enables them to acquire or reinforce their knowledge, without any risk for the patients, in a calm and reassuring environment. In psychiatry in particular, the use of a room of errors constitutes a useful learning tool for professionals.
March 2017: Soins; la Revue de Référence Infirmière
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