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https://www.readbyqxmd.com/read/29663540/extreme-toughening-of-soft-materials-with-liquid-metal
#1
Navid Kazem, Michael D Bartlett, Carmel Majidi
Soft and tough materials are critical for engineering applications in medical devices, stretchable and wearable electronics, and soft robotics. Toughness in synthetic materials is mostly accomplished by increasing energy dissipation near the crack tip with various energy dissipation techniques. However, bio-materials exhibit extreme toughness by combining multi-scale energy dissipation with the ability to deflect and blunt an advancing crack tip. Here, we demonstrate a synthetic materials architecture that also exhibits multi-modal toughening, whereby embedding a suspension of micron sized and highly deformable liquid metal (LM) droplets inside a soft elastomer, the fracture energy dramatically increases by up to 50x (from 250 ± 50 J m-2 to 11,900 ± 2600 J m-2 ) over an unfilled polymer...
April 16, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29650745/circles-of-care-for-people-with-intellectual-and-developmental-disabilities-communication-collaboration-and-coordination
#2
REVIEW
Karen McNeil, Meg Gemmill, Dara Abells, Samantha Sacks, Terry Broda, Catherine R Morris, Cynthia Forster-Gibson
OBJECTIVE: To review health information exchange (HIE) processes that affect the health of people with intellectual and developmental disabilities (IDD) and to suggest practical tips and strategies for communicating, collaborating, and coordinating in the primary care setting. SOURCES OF INFORMATION: The "Primary care of adults with intellectual and developmental disabilities. 2018 Canadian consensus guidelines" literature review and interdisciplinary input...
April 2018: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29626926/interpreting-chromosomal-rearrangements-in-the-context-of-3-dimentional-genome-organization-a-practical-guide-for-medical-genetics
#3
REVIEW
V S Fishman, P A Salnikov, N R Battulin
In this exciting era of "next-gen cytogenetics", the use of novel molecular methods such as comparative genome hybridization and whole genome and whole exome sequencing becomes more and more common in clinics. This results in generation of large amounts of high-resolution patient-specific data and challenges the development of new approaches for interpretation of obtained information. Usually, interpretation of chromosomal rearrangements is focused on alterations of linear genome sequence, underestimating the role of spatial chromatin organization...
April 2018: Biochemistry. Biokhimii︠a︡
https://www.readbyqxmd.com/read/29616176/surgical-treatment-for-kirner-s-deformity-single-osteotomy-through-a-palmar-approach
#4
Emiko Horii, Junko Otsuka, Shukuki Koh
Background: Patients with Kirner's deformity often seek medical attention for aesthetic improvement when they reach the age of approximately 10 years, when the deformity becomes evident. The operative technique described in textbooks is the palmar opening-wedge with multiple osteotomies through a mid-lateral incision, which is technically demanding. The purpose of this article was to introduce our surgical technique of a single transverse osteotomy through a palmar approach and to present the short-term outcomes of this technique...
February 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29614542/-gastrointestinal-bleeding-update
#5
Jonel Trebicka, Martin Götz
PREENDOSCOPIC MANAGEMENT:  In suspected gastrointestinal bleeding (GIB), standard operating procedures help in risk stratification, early patient management and endoscopy. If variceal bleeding is suspected, specific medication (vasoconstrictors, antimicrobial therapy) are additive to standard pharmacological management (PPI, erythromycin) prior to endoscopy. COAGULATION REQUIRMENTS:  An emergency endoscopy can be performed independent of the patient's current coagulation status...
April 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29607185/a-novel-suction-based-lung-stabilizing-device-for-video-assisted-thoracoscopic-surgical-procedures
#6
Yusuke Muranishi, Toshihiko Sato, Yuichiro Ueda, Yojiro Yutaka, Yasuto Sakaguchi, Tatsuo Nakamura, Hiroshi Date
Video-assisted thoracoscopic surgery (VATS) has become more commonly used in recent years. To provide a sufficient field of view during these procedures, surgeons must manipulate the lung using conventional devices such as cotton-tipped medical applicators and graspers. However, medical applicators are unable to pull on the target lung lobes, and graspers can damage the lung tissue. We developed a novel suction-based lung-stabilizing silicon device to easily and safely manipulate the lung in order to provide an optimal view during VATS procedures...
February 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29605243/diagnostic-and-prognostic-efficacy-of-coronary-flow-capacity-obtained-using-pressure-temperature-sensor-tipped-wire-derived-physiological-indices
#7
Rikuta Hamaya, Taishi Yonetsu, Yoshihisa Kanaji, Eisuke Usui, Masahiro Hoshino, Masao Yamaguchi, Masahiro Hada, Yoshinori Kanno, Tadashi Murai, Kenzo Hirao, Tsunekazu Kakuta
OBJECTIVES: This study aimed to evaluate the feasibility and efficacy of pressure-temperature sensor-tipped wire-derived coronary flow capacity (PTW-CFC) for assessing flow impairment and prognosis. BACKGROUND: CFC provides an integrated coronary physiological assessment in which coronary flow reserve and coronary flow during hyperemia are organized. METHODS: A total of 643 native de novo lesions for which physiological assessments were performed using a PressureWire (St...
March 23, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29602568/evaluation-of-ophthalmic-surgical-instrument-sterility-using-short-cycle-sterilization-for-sequential-same-day-use
#8
David F Chang, Nikki Hurley, Nick Mamalis, Jeffrey Whitman
PURPOSE: The common practice of short-cycle sterilization for ophthalmic surgical instrumentation has come under increased regulatory scrutiny. This study was undertaken to evaluate the efficacy of short-cycle sterilization processing for consecutive same-day cataract procedures. DESIGN: Testing of specific sterilization processing methods by an independent medical device validation testing laboratory. PARTICIPANTS: Phaco handpieces from 3 separate manufacturers were tested along with appropriate biologic indicators and controls using 2 common steam sterilizers...
March 27, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29581898/giant-left-ventricular-thrombus-in-a-patient-with-acute-ischemic-stroke-a-case-report-and-minireview
#9
Fan Ye, Burton V Silverstein, Matheen A Khuddus, Christopher L Bray, Arthur C Lee
A 56-year-old healthy male with no obvious risk factors or significant past medical history was admitted to the emergency room with acute ischemic stroke. On his transthoracic echocardiography (TTE), an extremely large thrombus was detected at the apex involving the distal anterior wall. The thrombus was predominantly adherent but with a mobile tip. The patient was subsequently managed with dual antiplatelet therapy. In this report, we present an interesting case of an acute ischemic stroke secondary to a giant left ventricular thrombus in a patient with no past significant cardiac or neurologic medical history...
2018: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29577037/chylous-ascites-a-review-of-pathogenesis-diagnosis-and-treatment
#10
REVIEW
Richa Bhardwaj, Haleh Vaziri, Arun Gautam, Enrique Ballesteros, David Karimeddini, George Y Wu
Chylous ascites (CA) is a rare form of ascites that results from the leakage of lipid-rich lymph into the peritoneal cavity. This usually occurs due to trauma and rupture of the lymphatics or increased peritoneal lymphatic pressure secondary to obstruction. The underlying etiologies for CA have been classified as traumatic, congenital, infectious, neoplastic, postoperative, cirrhotic or cardiogenic. Since malignancy and cirrhosis account for about two-thirds of all the cases of CA in Western countries, in this article we have attempted to reclassify CA based on portal and non-portal etiologies...
March 28, 2018: Journal of Clinical and Translational Hepatology
https://www.readbyqxmd.com/read/29570006/use-of-the-apollo-detachable-tip-microcatheter-for-endovascular-embolization-of-arteriovenous-malformations-and-arteriovenous-fistulas
#11
Bruno C Flores, Alfred P See, Gregory M Weiner, Brian T Jankowitz, Andrew F Ducruet, Felipe C Albuquerque
OBJECTIVE Liquid embolic agents have revolutionized endovascular management of arteriovenous malformations (AVMs) and arteriovenous fistulas (AVFs). Nonetheless, since 2005, the US FDA has received more than 100 reports of microcatheter breakage or entrapment related to Onyx embolization, including 9 deaths. In 2014, the Apollo detachable-tip microcatheter became the first of its kind available in the US. Since then, few reports on its safety have been published. METHODS The authors conducted a retrospective review of endovascular cases by searching the patient databases at 2 tertiary cerebrovascular centers (Barrow Neurological Institute and University of Pittsburgh Medical Center)...
March 23, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29569822/a-systematic-review-of-drug-treatment-of-vulvodynia-evidence-of-a-strong-placebo-effect
#12
Glaucia Miranda Varella Pereira, Milena Soriano Marcolino, Zilma Silveira Nogueira Reis, Marilene Vale de Castro Monteiro
BACKGROUND: Vulvodynia is the most common type of chronic pelvic pain and dyspareunia in premenopausal women. The effect of drugs for the treatment of vulvodynia remains poorly discussed. OBJECTIVES: To conduct a systematic review of randomised controlled studies which assess medications used to treat vulvar pain in vulvodynia. SEARCH STRATEGY: Web of Science, Cochrane Library, EBSCO Academic, LILACS and MEDLINE were searched from 1985 to September 2016...
March 23, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29564369/search-pattern-training-for-evaluation-of-central-venous-catheter-positioning-on-chest-radiographs
#13
William F Auffermann, Elizabeth A Krupinski, Srini Tridandapani
The goal of this research was to examine whether search pattern training for central line positioning on chest radiographs (CXRs) improves the ability of healthcare trainees and practitioners to identify malpositioned central venous catheters. Two sets of CXRs with central catheters were shown; half of the images contained catheters that were appropriately positioned, half that were malpositioned. Subjects were asked to: mark the tip of the catheter using the simulated radiology workstations, indicate their confidence in tip localization, and state whether the catheter was appropriately positioned or malpositioned...
July 2018: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29562841/real-time-ultrasound-guided-placement-of-peripherally-inserted-central-venous-catheter-without-fluoroscopy
#14
Soshi Nakamuta, Toshihiro Nishizawa, Shiori Matsuhashi, Arata Shimizu, Toshio Uraoka, Masato Yamamoto
BACKGROUND AND AIM: Malposition of peripherally inserted central catheters placed at the bedside is a well-recognized phenomenon. We report the success rate of the placement of peripherally inserted central catheters with ultrasound guidance for tip positioning and describe the knacks and pitfalls. MATERIALS AND METHODS: We retrospectively reviewed the medical case charts of 954 patients who received peripherally inserted central catheter procedure. Patient clinical data included success rate of puncture, detection rate of tip malposition with ultrasonography, adjustment rate after X-ray, and success rate of peripherally inserted central catheter placement...
March 1, 2018: Journal of Vascular Access
https://www.readbyqxmd.com/read/29560786/effect-of-catheter-diameter-on-left-innominate-vein-in-breast-cancer-patients-after-totally-implantable-venous-access-port-placement
#15
Myung Gyu Song, Tae-Seok Seo, Yun Hwan Kim, Sung Bum Cho, Hwan Hoon Chung, Seung Hwa Lee, Euichul Jung
The effect of catheter diameter on left innominate vein stenosis in breast cancer patients after totally implantable venous access port placement. PURPOSE: To evaluate the effect of catheter diameter on left innominate vein stenosis in breast cancer patients after placement of totally implantable venous access ports. MATERIALS AND METHODS: Totally implantable venous access ports were placed via the left internal jugular vein in 241 women with right breast cancer from January 2010 to December 2014 (mean age, 51...
March 1, 2018: Journal of Vascular Access
https://www.readbyqxmd.com/read/29554316/concurrent-placement-of-bilateral-suboccipital-and-supraorbital-nerve-stimulators-using-on-q-tunneler-technical-note
#16
Lara Massie, Rushna Ali, Konstantin V Slavin, Jason M Schwalb
BACKGROUND: Stimulation of the occipital and supraorbital nerves is used to treat chronic migraine refractory to medical management. Placement of cranial leads is often challenging due to the rigid Touhy needle included in the kit for its placement. OBJECTIVE: To report the first case of concurrent placement of bilateral supraorbital (SNS) and occipital nerve stimulators (ONS) from a unilateral approach using the On-Q* Tunneler, (Halyard Health, Alpharetta, Georgia) a flexible, blunt tipped plastic tunneler with a tear-away sheath...
March 14, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29550756/case-of-hepatic-flexure-ectopic-pregnancy-medically-managed-with-methotrexate
#17
Charlotte Elizabeth Trail, Andrew Watson, Alice Martha Schofield
Abdominal pregnancies represent 1.4% of extrauterine pregnancies. A literature search of six cases involving bowel ectopic pregnancies provided anecdotal treatment options. This case involves a woman admitted at 6 weeks gestation with right iliac fossa and shoulder tip pain. An ultrasound scan revealed an empty uterus with free fluid in both adnexa and a 31×21 mm heterogenous mass adjacent to the right ovary. At laparoscopy, an ectopic pregnancy was identified at the hepatic flexure. The patient received two doses of methotrexate and monitored until the beta human chorionic gonadotropin reduced...
March 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29548033/minor-behavioral-health-readiness-and-profiling-barriers-in-the-u-s-army
#18
Justin M Curley, Coleen Crouch, Joshua E Wilk
Introduction: Medical readiness for deployment is arguably the most important component of personnel readiness in the U.S. Army. Administrative documents called profiles provide individualized medical recommendations to the commander regarding how to best provide for a soldier's health and welfare, and contribute to an aggregated enumeration of a unit's overall readiness to deploy. Profiles that convey behavioral health (BH) limitations thus reflect what can be called the "behavioral health readiness" of the force...
March 14, 2018: Military Medicine
https://www.readbyqxmd.com/read/29545037/evolution-of-the-ureteral-stent-the-pivotal-role-of-the-gibbons-ureteral-catheter
#19
Ryan P Donahue, Andrew W Stamm, Robert P Gibbons, Christopher R Porter, Kathleen C Kobashi, John M Corman, Una J Lee
INTRODUCTION: The ureteral stent is engrained in the fabric of urologic practice. Virginia Mason Medical Center had a unique role in its development through the pioneering work of Dr. Robert Gibbons. Here, we review his contribution to the evolution of the modern ureteral stent. METHODS: We reviewed Dr. Gibbons' extensive work through primary sources, including interviews, projector slides, radiology images, stent prototypes, his personal writings and archived documents...
March 12, 2018: Urology
https://www.readbyqxmd.com/read/29537996/comparative-outcomes-in-functional-rhinoplasty-with-open-vs-endonasal-spreader-graft-placement
#20
Jason Talmadge, Robin High, William Wesley Heckman
IMPORTANCE: Spreader grafts are commonly used for nasal valve stenosis. There is debate among practitioners regarding the optimal approach for spreader graft placement. OBJECTIVE: This study aimed to determine whether an endonasal spreader graft placement leads to equivalent postoperative outcomes using a standardized nasal obstruction symptom score and whether there is a significant difference in operative time between the 2 approaches. DESIGN: A retrospective review of functional rhinoplasties by a single facial plastic surgeon over a 2-year period was conducted...
March 13, 2018: Annals of Plastic Surgery
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