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Mieczysław Grzesik, Krzysztof Górnik, Regina Janas, Mariusz Lewandowki, Zdzislawa Romanowska-Duda, Bert van Duijn
The aim of the study was to improve the effect of stratification of apple "Ligol" seeds by application of selected compounds, phytohormones, and physical methods For this purpose the seeds were stratified at 3°C in distilled water or in the presence of potassium nitrate (KNO3), ethephon (ET), carbon monoxide (CO), hydrogen peroxide (H2O2), a mixture of KNO3, ET, CO, H2O2, gibberellins (GA3), 6-benzylaminopurine (BAP), jasmonic acid (JA), salicylic acid (SA) and a mixture of SA, GA3, BAP, JA, nitric oxide (NO), hydrogen chloride (HCL)...
September 28, 2017: Journal of Plant Physiology
Zhao Guo, Shuang Zhu, Yuan Yong, Xiao Zhang, Xinghua Dong, Jiangfeng Du, Jiani Xie, Qing Wang, Zhanjun Gu, Yuliang Zhao
Developing an effective theranostic nanoplatform remains a great challenge for cancer diagnosis and treatment. Here, BiOI@Bi2 S3 @BSA (bovine serum albumin) semiconductor heterojunction nanoparticles (SHNPs) for triple-combination radio/photodynamic/photothermal cancer therapy and multimodal computed tomography/photoacoustic (CT/PA) bioimaging are reported. On the one hand, SHNPs possess strong X-ray attenuation capability since they contain high-Z elements, and thus they are anticipated to be a very competent candidate as radio-sensitizing materials for radiotherapy enhancement...
October 16, 2017: Advanced Materials
Francesco Menzella, Mirco Lusuardi, Carla Galeone, Nicola Facciolongo
Asthma is characterized by inflammation of the airways that includes eosinophils, basal membrane thickening, epithelial sloughing, vascular changes, smooth muscle hypertrophy and hyperplasia, and mucous gland hyperplasia. Recently, there have been studies on the role of hypersensitivity and inflammation in asthma, but the role of bronchial smooth muscle remains unclear. Bronchial thermoplasty is an endoscopic procedure that is approved by the US Food and Drug Administration (FDA) for the treatment of severe refractory asthma, based on the local delivery of radio frequency at 65°C to the airways, with the aim of controlling bronchospasm through a reduction of airway smooth muscle (ASM)...
2017: Therapeutics and Clinical Risk Management
Vinay Ganapathy, Ramesh Ramachandran
The response of a quadrupolar nucleus (nuclear spin with I >12) to an oscillating radio-frequency pulse/field is delicately dependent on the ratio of the quadrupolar coupling constant to the amplitude of the pulse in addition to its duration and oscillating frequency. Consequently, analytic description of the excitation process in the density operator formalism has remained less transparent within existing theoretical frameworks. As an alternative, the utility of the "concept of effective Floquet Hamiltonians" is explored in the present study to explicate the nuances of the excitation process in multilevel systems...
October 14, 2017: Journal of Chemical Physics
Blair P Dudeck, Michael Clinchy, Marek C Allen, Liana Y Zanette
Fear itself (perceived predation risk) can affect wildlife demography, but the cumulative impact of fear on population dynamics is not well understood. Parental care is arguably what most distinguishes birds and mammals from other taxa, yet only one experiment on wildlife has tested fear effects on parental food provisioning and the repercussions this has for the survival of dependent offspring, and only during early-stage care. We tested the effect of fear on late-stage parental care of mobile dependent offspring, by locating radio-tagged song sparrow fledglings and broadcasting predator or non-predator playbacks in their vicinity, measuring their parent's behaviour and their own, and tracking the offspring's survival to independence...
October 14, 2017: Ecology
El Mostafa Benchafia, Zhenhua Yao, Gu Yuan, Tsengmin Chou, Hong Piao, Xianqin Wang, Zafar Iqbal
The long-sought cubic gauche phase of polymeric nitrogen (cg-PN) with nitrogen-nitrogen single bonds has been synthesized together with a related phase by a radio-frequency plasma reaction under near-ambient conditions. Here, we report the synthesis of polymeric nitrogen using a mixture of nitrogen and argon flowing over bulk β-sodium azide or β-sodium azide dispersed on 100 nm long multiwall carbon nanotubes. The cg-PN phase is identified by Raman and attenuated total reflection-Fourier transform infrared spectroscopy, and powder X-ray diffraction...
October 13, 2017: Nature Communications
Sarkhosh S Chaharborj, Abbas Moameni
In this article, fractional calculus has been applied to study the motion of ions in a three-dimensional radio frequency quadrupole ion trap; we have called this arrangement a fractional quadrupole ion trap. The main purpose of the article is to show that by controlling the fractional parameter of a trapped ion, one can gain a more efficient mass separation. In what follows, we will see that with decreasing the fractional parameter, we can achieve a smaller first stability region. Note that a small stability diagram will result in a good and acceptable mass separation...
October 2017: European Journal of Mass Spectrometry
Przemyslaw Krehlik, Harald Schnatz, Lukasz Sliwczynski
We describe a fiber-optic solution for simultaneous distribution of all signals generated at today's most advanced time and frequency laboratories, i.e. an ultrastable optical reference frequency derived from an optical atomic clock, a radio frequency precisely linked to a realization of the SI-Second, and a realization of an atomic timescale, being the local representation of the virtual, global UTC timescale. In our solution both the phase of the optical carrier and the delay of electrical signals (10 MHz frequency reference and one pulse-persecond time tags) are stabilized against environmental perturbations influencing the fiber link instability and accuracy...
October 12, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Wenhao Li, Xiang Peng, Dmitry Budker, Arne Wickenbrock, Bo Pang, Rui Zhang, Hong Guo
Dynamic hybrid optical pumping effects with a radio-frequency field-driven nonlinear magneto-optical rotation scheme are studied in a dual-species paraffin coated vapor cell. By pumping K atoms and probing Rb87 atoms, we achieve an intrinsic magnetic resonance linewidth of 3 Hz, and the observed resonance is immune to power broadening and light-shift effects. Such an operation scheme shows favorable prospects for atomic magnetometry applications.
October 15, 2017: Optics Letters
Prasanna Naik, M M A Faridi, Prerna Batra, S V Madhu
BACKGROUND: Exclusively breastfed infants are at increased risk of vitamin D deficiency and many lactating mothers have been found deficient in 25OHD stores. OBJECTIVE: To compare serum vitamin D levels in exclusively breastfed infants at 6 months of age with or without oral supplementation of 600,000 IU of vitamin D3 to mothers in early postpartum period. METHODS: Exclusively breastfeeding term parturient mothers were randomized 24-48 hours following delivery to receive either 600,000 IU of vitamin D3 (Cholecalciferol) over 10 days in a dose of 60,000 IU/day or placebo...
October 13, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
Benjamin Frey, Michael Rückert, Lisa Deloch, Paul F Rühle, Anja Derer, Rainer Fietkau, Udo S Gaipl
Ionizing radiation is often regarded as an element of danger. But, danger responses on the cellular and molecular level are often beneficial with regard to the induction of anti-tumor immunity and for amelioration of inflammation. We outline how in dependence of radiation dose and fraction, radiation itself-and especially in combination with immune modulators-impacts on the innate and adaptive immune system. Focus is set on radiation-induced changes of the tumor cell phenotype and the cellular microenvironment including immunogenic cancer cell death...
November 2017: Immunological Reviews
Kouki Tomari, Masahiro Goto, Aya Shimada, Hiroko Yagi, Yuka Nagashima, Yukihiro Hasegawa
There are three major therapeutic options for the treatment of Graves' disease (GD): antithyroid drugs (ATDs), thyroidectomy, and radio-iodine (RAI) therapy. ATDs are the initial treatment option for children. However, some pediatric GD patients who are initially treated with ATDs require other type of treatments later on. We reviewed the medical records of childhood-onset GD cases retrospectively to report the clinical course of patients who received either surgery or RAI therapy subsequent to treatment with ATDs...
2017: Clinical Pediatric Endocrinology: Case Reports and Clinical Investigations: Official Journal of the Japanese Society for Pediatric Endocrinology
Bruno Di Maggio, Pasquale Sessa, Patrizia Mantelli, Pietro Maniscalco, Fabrizio Rivera, Giorgio Maria Calori, Luigi Bisogno, Gabriele Scaravilli, Marco Caforio
INTRODUCTION: Open reduction and internal fixation (ORIF) with plate and screws represents the recommended treatment for unstable intra-articular distal radius fractures. Although significant progresses in surgical technique have been made, anatomical reconstruction of radio-carpal articular surface still represent a difficult task, especially in multifragmentary fractures. Available PEEK reinforced-carbon fiber composite radiolucent devices allow both an easier and more careful assessment of intra-operative reduction of the articular surface of distal radius and prompt correction of any residual step deformity...
October 2017: Injury
Zhao Jinping, Chu Qing, Song Wenying, Yang Chunyan, Xiang Lili, Shi Yao, Wang Yumin, Xu Zhenzhen, Zhang Li, Gao Yuguang
OBJECTIVE: Compelling evidence suggests that mitogen-activated protein kinases (Mapks) play an important role in amelogenesis. However, the role of transforming growth factor (TGF)-β-activating kinase 1 (Tak1, Map3k7), which is a known upstream kinase of Mapks, during amelogenesis remains to be determined. The aim of this study was to investigate the possible involvement of Map3k7 in amelogenesis. DESIGN: We generated transgenic mice that produced constitutively active human MAP3K7 (caMAP3K7) under the control of amelogenin (Amelx) gene promoter...
September 25, 2017: Archives of Oral Biology
Franziska Menzel, Nicole Kaiser, Susann Haehnel, Felicitas Rapp, Ina Patties, Nina Schöneberg, Zhana Haimon, Kerstin Immig, Ingo Bechmann
Irradiation is widely used to treat brain tumors, and also to create bone marrow (BM) chimeras. BM chimeras are widely used to dissect functions and origin of microglia and blood-derived mononuclear cells under homeostatic or pathological conditions. This is facilitated by the fact that microglia survive irradiation and are thus regarded radio-resistant. In this study, we tested whether microglia are indeed radio-resistant and looked for potential mechanisms that might explain this phenomenon. We analyzed the radio-resistance of microglia independently of their physiological brain environment compared to other mononuclear cells from spleen and brain after X-irradiation with 7 Gy or 30 Gy...
October 10, 2017: Glia
Ying Chen, Hardeep S Mehta, Mark C Butler, Eric D Walter, Patrick N Reardon, Ryan S Renslow, Karl T Mueller, Nancy M Washton
We present the numerical optimization and experimental characterization of two microstrip-based nuclear magnetic resonance (NMR) detectors. The first detector, introduced in our previous work, was a flat wire detector with a strip resting on a substrate, and the second detector was created by adding a ground plane on top of the strip conductor, separated by a sample-carrying capillary and a thin layer of insulator. The dimensional parameters of the detectors were optimized using numerical simulations with regards to radio frequency (RF) sensitivity and homogeneity, with particular attention given to the effect of the ground plane...
October 12, 2017: Physical Chemistry Chemical Physics: PCCP
Ruggero Rodriguez Y Baena, Riccardo D'Aquino, Antonio Graziano, Letizia Trovato, Antonio C Aloise, Gabriele Ceccarelli, Gabriella Cusella, André A Pelegrine, Saturnino M Lupi
Sinus lift augmentation is a procedure required for the placement of a dental implant, whose success can be limited by the quantity or quality of available bone. To this purpose, the first aim of the current study was to evaluate the ability of autologous periosteum-derived micrografts and Poly(lactic-co-glycolic acid) (PLGA) supplemented with hydroxyl apatite (HA) to induce bone augmentation in the sinus lift procedure. Secondly, we compared the micrograft's behavior with respect to biomaterial alone, including Bio-Oss® and PLGA/HA, commercially named Alos...
2017: Frontiers in Cell and Developmental Biology
Jiayi Yu, Yanyi Xu, Shan Li, Gabrielle V Seifert, Matthew L Becker
Hydroxyapatite (HA) nanocrystals were blended with 1,6-hexanediol L-phenylalanine-based poly(ester urea) (PEU). These composites were 3D-printed into porous scaffolds (75% porosity) via fused deposition modeling (FDM) technique and seeded with MC3T3-E1 pre-osteoblast cells in vitro to examine their bioactivity. The resulting 3D-printed scaffolds exhibited a compressive modulus of ~50 MPa after 1-week incubation in PBS at 37 °C, a cell viability of >95%, and a composition dependent enhancement of radio-contrast...
October 11, 2017: Biomacromolecules
Ranran Fan, Fei Lu, Kaikai Li
Photoluminescence (PL) of Er and Ge co-doped ZnO films synthesized by radio frequency magnetron co-sputtering was investigated. X-ray diffraction (XRD) patterns showed that the annealing process at 400-800 °C led to the formation of nanocrystal (nc) Ge. Samples containing nc-Ge showed a strong visible PL with a peak at 582-593 nm, which was consistent with the calculated energy of the exciton of the ~5 nm-sized nc-Ge, according to the quantum confinement effect. The formation of nc-Ge could greatly enhance the 1...
October 11, 2017: Nanomaterials
Sonia Medina, Luigi Tamè, Matthew R Longo
Identifying the spatial location of touch on the skin surface is a fundamental function of our somatosensory system. Despite the fact that stimulation of even single mechanoreceptive afferent fibres is sufficient to produce clearly localised percepts, tactile localisation can be modulated also by higher level processes such as body posture. This suggests that tactile events are coded using multiple representations using different coordinate systems. Recent reports provide evidence for systematic biases on tactile localisation task, which are thought to result from a supramodal representation of the skin surface...
October 10, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
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