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bladder outlet obstruction

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https://www.readbyqxmd.com/read/27900218/a-prospective-randomised-controlled-study-comparing-bipolar-plasma-vaporisation-of-the-prostate-to-monopolar-transurethral-resection-of-the-prostate
#1
Ahmed M Elsakka, Hssan H Eltatawy, Khaled H Almekaty, Ahmed R Ramadan, Tarik A Gameel, Yasser Farahat
OBJECTIVES: To compare the safety and efficacy of bipolar transurethral plasma vaporisation (B-TUVP) as an alternative to the 'gold standard' monopolar transurethral resection of the prostate (M-TURP) for the treatment of benign prostatic hyperplasia (BPH) in a prospective randomised controlled study. PATIENTS AND METHODS: In all, 82 patients indicated for prostatectomy were assigned to two groups, group I (40 patients) underwent B-TUVP and group II (42 patients) underwent M-TURP...
December 2016: Arab Journal of Urology
https://www.readbyqxmd.com/read/27876076/bladder-outlet-obstruction-a-rare-complication-of-the-neglected-schistosome-schistosoma-haematobium-two-case-reports-and-public-health-challenges
#2
Valirie Ndip Agbor, Tsi Njim, Franklin Ngu Mbolingong
BACKGROUND: Schistosomiasis is a severe parasitic infestation with debilitating complications and is the third most devastating tropical disease in the world. It is one of the neglected tropical diseases (NTDs) with a high disease-burden. We present two rare cases of bladder outlet obstruction: one which led to a chronic kidney disease and ultimately death and a second which recovered after treatment with praziquantel. CASE PRESENTATIONS: A 72 year old male presented with lower urinary tract symptoms which culminated in an episode of acute urinary retention...
November 22, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27847918/does-uroflowmetry-parameter-facilitate-discrimination-between-detrusor-underactivity-and-bladder-outlet-obstruction
#3
Kwon Soo Lee, Phil Hyun Song, Young Hwii Ko
PURPOSE: Though urodynamic study (UDS) is the current established standard to distinguish between detrusor underactivity (DU) and bladder outlet obstruction (BOO), concerns of patient discomfort and potential complications of catheterization deters its use. We inspected clinical variables to discriminate between DU and BOO in uroflowmetry, which can be more easily performed in clinical practice. MATERIALS AND METHODS: Total 240 men who both underwent UDS and uroflowmetry were reviewed...
November 2016: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/27845695/-prognostic-factors-for-the-efficacy-of-silodosin-in-the-treatment-of-symptomatic-benign-prostatic-hyperplasia-subanalysis-of-the-ural-study
#4
Jesús Salinas-Casado, Miguel Vírseda-Chamorro, Santiago Méndez-Rubio, Marcos Luján-Galán, Manuel Esteban-Fuertes, Jesús Moreno-Sierra
OBJECTIVE: To identify the prognostic factors influencing the clinical and urodynamics results on symptomatic benign prostatic hypertrophy (BHP) treatment in a series of patients with silodosin therapy from the URAL study. METHODS: A retrospective study was performed in a cohort of 318 patients with BPH which underwent silodosine treatment, during at least 12 weeks. RESULTS: Univariate analysis demonstrated that the variables in relationship with a decrease of urinary symptoms` punctuation postreatment (measured with the IPSS Questionnaire), a maximum peak flow (Q max) postreatment equal or superior to 15 ml/s, a postreatment postvoid residual lower to 100 ml, and a postreatment obstruction index ( Bladder Outlet Obstruction Index: BOOI) equal or lower to 20 cm H2O, presented such both as a clinical and urodynamic character...
November 2016: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/27844406/partial-bladder-outlet-obstruction-is-associated-with-decreased-expression-and-function-of-the-small-conductance-ca-2-activated-k-channel-in-guinea-pig-detrusor-smooth-muscle
#5
Ning Li, Xiaoning He, Zizheng Li, Yili Liu, Ping Wang
PURPOSE: Partial bladder outlet obstruction (PBOO) usually induces overactive bladder (OAB) associated with detrusor overactivity (DO) which is related to the increased contractility of detrusor smooth muscle (DSM). The pharmacological activation of small-conductance Ca(2+)-activated K(+) (SK) channels dramatically attenuates DSM contractility. However, the role of SK channels in the PBOO DSM is less clear. Here, we tested the hypothesis that PBOO is associated with decreased expression and function of SK channels in DSM and that the activation of SK channels is a potential target to regulate DO...
November 14, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27843222/prolapsing-cystitis-cystica-causing-bladder-outlet-obstruction-an-unusual-complication
#6
Pankaj Halder, Kartik Chandra Mandal, Sumedha Mukherjee
Cystitis cystica (CC) is aproliferative disorder of bladder urothelium and usually subsides with medical therapy. However, this is not true for severe CC where surgical intervention is required to control breakthrough urinary tract infection (UTI). It may be mistaken as bladder neoplasm or posterior urethral valve, especially in children. Here, we report a case of CC in a 2-year-old boy where we had to excise the large pedunculated intravesical lesion to control breakthrough UTI and ongoing renal damage.
October 2016: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/27842627/polyarteritis-nodosa-presenting-as-a-bladder-outlet-obstruction
#7
M Borkum, H Y Abdelrahman, R Roberts, A A Kalla, I G Okpechi
Polyarteritis nodosa (PAN) of the urinary tract is rare. An unusual case of systemic PAN involving the bladder neck is described. A 27-year-old man, with known diastolic hypertension diagnosed 2 years earlier, was admitted with chronic urinary obstruction complicated by hydronephrosis. He had symptoms of myalgia and weight loss, was afebrile but had an elevated erythrocyte sedimentation rate and acute-on-chronic renal impairment. All virological and serological tests including hepatitis B and anti-neutrophil cytoplasmic antibody were negative...
November 2, 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/27800470/holmium-laser-enucleation-of-the-prostate-patient-selection-and-perspectives
#8
REVIEW
Tracy Marien, Mustafa Kadihasanoglu, Nicole L Miller
BACKGROUND: Multiple endoscopic surgical options exist to treat benign prostatic hyperplasia (BPH), including holmium laser enucleation of the prostate (HoLEP). HoLEP alleviates obstructive prostatic tissue via enucleation, both bluntly with a resectoscope and by cutting tissue with the holmium laser, and removal of adenoma via morcellation. This article reviews patient selection for HoLEP in order to optimize outcomes, costs, and patient satisfaction. METHODS: A literature review of all studies on HoLEP was conducted...
2016: Research and Reports in Urology
https://www.readbyqxmd.com/read/27794187/the-relevance-of-immune-responses-to-partial-bladder-outlet-obstruction-and-reversal
#9
Wei-Yu Lin, Yi-Pai Lin, Robert M Levin, Miaw-Ling Chen
AIMS: Partial bladder outlet obstruction (PBOO) causes tissue inflammation, a significant increase in markers of systemic oxidative stress, and proliferation of circulating myeloid-derived suppressor cells. Here, we investigated the regulatory mechanisms underlying inflammation and helper T cell involvement in PBOO. METHODS: Surgical PBOO was performed in four groups of rats: control (C), obstruction at 2 (O2) and 4 (O4) weeks, and 4 weeks after the relief of PBOO (R4) (n = 6 each)...
October 29, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27794178/the-effect-of-doxazosin-and-sildenafil-citrate-combination-on-bladder-tissue-contractility-alpha-adrenergic-receptor-and-inos-subtype-expression-in-a-male-rat-model-of-partially-bladder-outlet-obstruction
#10
Abdulkadir Gumrah, Yiloren Tanidir, Ilker Tinay, Mustafa Ozyurek, Tufan Tarcan
AIMS: Our aim was to investigate the effects of doxazosin, sildenafil, and their combination on bladder tissue contractility and adrenergic receptor (AR) and inducible nitric oxide synthase (iNOS) expression utilizing a male rat model of partial urethral obstruction (PUO). METHODS: Thirty male Sprague Dawley rats were divided into five groups. Except the SHAM group, all animals in remaining four groups underwent surgery for PUO. No further treatment was given to the first group (NT group)...
October 29, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27790521/incisional-hernia-as-a-cause-of-blader-outlet-obstruction-a-case-report
#11
Suhani, Shadan Ali, Gunjan Desai, Kartikeya Sharma, Shaji Thomas
Incisional hernia usually contains intra peritoneal organs as its content. Extra peritoneal structures like bladder as a content of incisional hernia are relatively uncommon. We managed a young male with an incisional hernia containing a large bladder diverticulum as its content. The bladder diverticulum was going up to the base of scrotum along the posterolateral surface of penile corpora. The patient was diagnosed pre operatively with radiological investigations and underwent exploration with release of diverticulum from corpora and pubic arch followed by diverticulectomy and herniorraphy...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27784873/atp-release-from-bladder-urothelium-and-serosa-in-a-rat-model-of-partial-bladder-outlet-obstruction
#12
Kazuhiro Shiina, Ken-Ichiro Hayashida, Kazuo Ishikawa, Masahito Kawatani
Overactive bladder is one of the major health problem especially in elderly people. Adenosine triphosphate (ATP) is released from urinary bladder cells and acts as a smooth muscle contraction and sensory signal in micturition but little is known about the role of ATP release in the pathophysiology of overactive bladder. To assess the relationship between ATP and overactive bladder, we used a partial bladder outlet obstruction (pBOO) model in rats. The bladder caused several changes by pBOO: An increase in bladder weight, hypertrophy of sub-urothelium and sub-serosal area, and frequent non-voiding bladder contraction during urine storage...
2016: Biomedical Research
https://www.readbyqxmd.com/read/27778388/detrusor-overactivity-increases-bladder-wall-thickness-in-male-patients-a-urodynamic-multicenter-cohort-study
#13
Cosimo De Nunzio, Fabrizio Presicce, Riccardo Lombardo, Simon Carter, Carlo Vicentini, Andrea Tubaro
AIMS: To evaluate the role of Bladder wall thickness (BWT) as a predictor of Detrusor overactivity (DO) in patients with Lower urinary tract symptoms (LUTS)/Benign prostatic enlargement without Bladder Outlet Obstruction. METHODS: From January 1996 to December 2000, each new patient, aged 45 years or older with LUTS, underwent standard diagnostic assessment, urodynamic studies (cystometry and pressure flow studies), and ultrasound measurements of the bladder wall thickness (BWT) in two centers...
October 24, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27771424/impact-of-minimally-invasive-benign-prostatic-hyperplasia-therapies-on-30-and-90-day-postoperative-office-encounters
#14
Ram A Pathak, Gregory A Broderick, Todd C Igel, Steven P Petrou, Paul R Young, Michael J Wehle, Michael G Heckman, Nancy N Diehl, Emily R Vargas, Kandarp Shah, David D Thiel
OBJECTIVE: To compare the frequency of postoperative encounters in the 30-day and 90-day postoperative periods for various bladder outlet obstruction surgical therapies. METHODS: All patients who underwent transurethral resection of the prostate (TURP), GreenLight laser photovaporization of the prostate (GL-PVP) (American Medical Systems Inc.), and holmium laser enucleation of the prostate (HoLEP) from January 1(st), 2012 through December 31(st), 2014 were followed for 6 months postoperatively...
October 19, 2016: Urology
https://www.readbyqxmd.com/read/27761589/-minimally-invasive-treatment-of-benign-prostatic-hyperplasia
#15
G Magistro, C G Stief, C Gratzke
Novel minimally invasive treatment options for the management of male lower urinary tract symptoms (LUTS) due to bladder outlet obstruction (BOO) aim to provide equal efficacy compared to standard techniques with a more favourable safety profile. The preservation of all aspects of male sexual function including antegrade ejaculation is increasingly important to patients. It should be ideally performed in an outpatient setting under local anesthesia to assure a short recovery time. Novel injectables for intraprostatic application (botulinum neurotoxin A, NX-1207, PRX302) have emerged and first phase III results could not confirm the promising initial data...
October 19, 2016: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/27756599/piezo1-expression-increases-in-rat-bladder-after-partial-bladder-outlet-obstruction
#16
Mai Michishita, Kazuo Yano, Ken-Ichi Tomita, Osamu Matsuzaki, Ken-Ichi Kasahara
AIMS: For patients with benign prostatic hyperplasia (BPH), storage symptoms due to bladder dysfunction are bothersome, and that mechanism elucidation is needed. Piezo1, a mechanically activated ion channel, is believed to play a role in sensing bladder distension. To investigate the involvement of Piezo1 in bladder dysfunction, we examined the expression and distribution of Piezo1 and neurofilament (NF-L) to understand pathological alterations in rat bladders with partial bladder outlet obstruction (pBOO), an animal model of BPH...
October 15, 2016: Life Sciences
https://www.readbyqxmd.com/read/27752927/%C3%AE-1-blockers-in-men-with-lower-urinary-tract-symptoms-suggestive-of-benign-prostatic-obstruction-is-silodosin-different
#17
REVIEW
Claus G Roehrborn, Francisco Cruz, Ferdinando Fusco
Available α1-blockers (ABs) have different profiles of receptor selectivity. Silodosin exhibits the highest selectivity for the α1A adrenergic receptor. This pharmacological feature couples with a singular urodynamic and clinical profile. The magnitude of bladder outlet obstruction improvement in patients receiving silodosin is higher if compared to other ABs. From a clinical point of view, current evidence suggests an advantage in favor of silodosin in terms of nocturia improvement and cardiovascular safety...
October 17, 2016: Advances in Therapy
https://www.readbyqxmd.com/read/27736908/urodynamic-investigation-a-valid-tool-to-define-normal-lower-urinary-tract-function
#18
Lorenz Leitner, Matthias Walter, Ulla Sammer, Stephanie C Knüpfer, Ulrich Mehnert, Thomas M Kessler
OBJECTIVES: To evaluate whether urodynamic investigation (UDI), the gold standard to assess refractory lower urinary tract symptoms (LUTS), is appropriate to select healthy volunteers with apparent normal lower urinary tract function as control subjects for comparative studies. SUBJECTS AND METHODS: 42 healthy subjects (22 women, mean age 32±10 years; 20 men, mean age 37±12 years) without LUTS were included into this prospective single-centre cohort study. All subjects recorded a 3-day bladder diary, completed validated questionnaires regarding LUTS, and underwent neuro-urological assessment as well as free uroflowmetry...
2016: PloS One
https://www.readbyqxmd.com/read/27721639/role-of-urodynamics-in-stress-urinary-incontinence-a-critical-appraisal
#19
Shirish Dattatraya Yande, Omkar Vinay Joglekar, Maya Joshi
INTRODUCTION: Role of urodynamics prior to surgery of stress urinary incontinence (SUI) is under constant debate. Demonstration of the presence of detrusor overactivity is the only aspect that has been emphasized in the literature so far. We believe that there are number of other factors which may influence the evaluation and in turn the choice of surgical management and prediction of outcome of treatment. They are as follows: (1) Presence of voiding inefficiency, (2) asymptomatic detrusor overactivity, (3) and severity of SUI...
July 2016: Journal of Mid-life Health
https://www.readbyqxmd.com/read/27707652/bladder-continent-catheterizable-conduit-the-mitrofanoff-procedure-long-term-issues-that-should-not-be-underestimated
#20
Alice Faure, Rebecca Cooksey, Aurore Bouty, Alan Woodward, John Hutson, Mike O'Brien, Yves Heloury
BACKGROUND: Effective bladder emptying by clean intermittent catheterization for children with severe bladder dysfunction is critical for renal preservation and social integration. Use of a continent catheterizable conduit (CCC) as urethral alternative procedure provides effective bladder drainage. However, it brings a substantive maintenance. METHODS: Retrospective review of the indications and long-term outcomes of 54 patients with a Mitrofanoff procedure in a single center over a 20-year period (1995-2015)...
September 23, 2016: Journal of Pediatric Surgery
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