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bladder outlet obstruction

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https://www.readbyqxmd.com/read/28807625/role-of-urodynamics-in-management-of-urethral-diverticulum-in-females
#1
Kuan-Jung Lin, Yu-Hua Fan, Alex Tong-Long Lin
BACKGROUND: Few studies have focused on the urodynamic findings of urethral diverticula (UD). We characterized the symptoms and urodynamic findings in women with UD. METHODS: A retrospective review of all women in a single center having surgical treatment for symptomatic UD between May 2004 and September 2014 was done. Lower urinary tract symptoms were evaluated with International Prostate Symptom Score and Overactive Bladder Symptom Score questionnaires. All patients underwent magnetic resonance imaging and videourodynamic study (VUDS) prior to surgery, and postoperative evaluation with VUDS...
August 11, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28795212/a-review-of-adverse-events-related-to-prostatic-artery-embolization-for-treatment-of-bladder-outlet-obstruction-due-to-bph
#2
Airton Mota Moreira, André Moreira de Assis, Francisco Cesar Carnevale, Alberto Azoubel Antunes, Miguel Srougi, Giovanni Guido Cerri
INTRODUCTION: Minimally invasive procedures have gained great importance among the treatments for benign prostate hyperplasia (BPH) due to their low morbidity. Prostate artery embolization has emerged as a safe and effective alternative for patients with large volume BPH, not suited for surgery. MATERIALS AND METHODS: Low adverse events rates have been reported following prostate artery embolization and may include dysuria, urinary infection, hematuria, hematospermia, acute urinary retention and rectal bleeding...
August 9, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28794589/is-urodynamic-study-is-a-necessity-for-evaluation-of-lower-urinary-tract-symptoms-in-postmenopausal-female-patients-result-of-a-prospective-observational-study
#3
Sunirmal Choudhury, Susanta Kumar Das, Debarshi Jana, Dilip Kumar Pal
AIM: The aim of this study is to evaluate the causes of lower urinary tract symptoms (LUTS) in postmenopausal female patients (PMFP) and correlate their symptoms with their urodynamic study (UDS) findings. MATERIALS AND METHODS: A prospective observational study analyzing the clinical and UDS findings of PMFP presenting with LUTS. A detailed history including history of diabetes, neurological disease, drug history, and pelvic surgeries was taken, followed by physical examination and urodynamic assessment...
July 2017: Urology Annals
https://www.readbyqxmd.com/read/28794586/does-prostate-size-predict-the-urodynamic-characteristics-and-clinical-outcomes-in-benign-prostate-hyperplasia
#4
Kawaljit Singh, Rahul Janak Sinha, Ashok Sokhal, Vishwajeet Singh
AIMS: Bladder outlet obstruction (BOO) in large and small prostates is managed in a similar manner despite considerably different pathophysiology, which can result in higher failure rates. We investigate the clinical and urodynamic features and study the outcome of patients with benign prostate hyperplasia (BPH) according to their prostate size. SUBJECTS AND METHODS: We prospectively analyzed 100 BPH patients undergoing urodynamic study between January 2015 and August 2016 and divided them into two groups according to their prostate size: small (≤30 mL) and large prostate (>30 mL) groups...
July 2017: Urology Annals
https://www.readbyqxmd.com/read/28794457/characteristics-of-the-mechanosensitive-bladder-afferent-activities-in-relation-with-microcontractions-in-male-rats-with-bladder-outlet-obstruction
#5
Naoki Aizawa, Koji Ichihara, Hiroshi Fukuhara, Tetsuya Fujimura, Karl-Erik Andersson, Yukio Homma, Yasuhiko Igawa
We investigated the characteristics of bladder mechanosensitive single-unit afferent activities (SAAs) in rats with a bladder outlet obstruction (BOO) and their relationship with bladder microcontractions. Male Wistar rats were divided into Sham and BOO groups. Four or 10 days after the surgery, rats were anesthetized with urethane. The SAAs of Aδ- or C-fibers from the L6 dorsal roots were recorded during bladder filling. The BOO group showed a higher number of microcontractions and lower SAAs of Aδ-fibers compared with those of the Sham group...
August 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28791388/bioinformatic-analysis-of-microrna-mrna-expression-profiles-of-bladder-tissue-induced-by-bladder-outlet-obstruction-in-a-rat-model
#6
Liu Jian Duan, Qi Feng Cao, Ding Xu, Hai Long Liu, Jun Qi
Various microRNAs (miRNAs) have previously been demonstrated to exhibit an association with the process of bladder remodeling, induced by bladder outlet obstruction (BOO). However, little is known about miRNA and gene expression profiles and the molecular mechanism underlying bladder pathophysiological alterations. The present study used bioinformatic analysis technology to examine the altered miRNA and mRNA expression profiles of bladder tissue in a rat model of BOO and validate the involved signaling pathways...
August 7, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28791238/the-underactive-bladder-diagnosis-and-surgical-treatment-options
#7
REVIEW
Johan Gani, Derek Hennessey
The underactive bladder (UAB)/detrusor underactivity (DU) is a relatively common condition. It is difficult to diagnose and can be difficult to manage. The aim of this review is to provide a review of the diagnosis and different surgical treatment options for UAB/DU. A comprehensive literature review using medical search engines was performed. The search included a combination of the following terms, UAB, DU, TURP, reduction cystoplasty, bladder diverticulectomy and sacral neuromodulation (SNM). Search results were assessed for their overall relevance to this review...
July 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28782261/minimally-invasive-measurement-of-vesical-pressure-for-diagnosis-of-infravesical-obstruction
#8
João C M de Almeida, Carlos A L D'Ancona, José W M Bassani
AIMS: This study was focused on the clinical test of an improved and portable version of a previously described urethral connector (UC), designed for minimally invasive measurement of vesical pressure and diagnosis of infravesical obstruction in men. METHODS: The conventional pressure-flow study (PFS) and the test with the new version of UC were applied to individuals reporting lower urinary tract symptoms (LUTS), who were then classified as obstructed or non-obstructed/equivocal based on the bladder outlet obstruction index (BOOI) from PFS data...
August 7, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28776126/management-of-urethral-stricture-and-bladder-neck-contracture-following-primary-and-salvage-treatment-of-prostate-cancer
#9
REVIEW
Brendan Michael Browne, Alex J Vanni
PURPOSE OF REVIEW: This article discusses the incidence, evaluation, and treatment of bladder outlet obstruction from urethral stricture, vesicourethral anastomotic stricture, and bladder neck contracture following primary and salvage treatment of prostate cancer. RECENT FINDINGS: Rates of stenosis after prostate cancer treatment appear similar across all primary treatment modalities including radical prostatectomy, radiation therapy, cryoablation, and high-intensity focused ultrasound in contemporary series...
October 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28768664/preventative-effects-of-a-hif-inhibitor-17-dmag-on-partial-bladder-outlet-obstruction-induced-bladder-dysfunction
#10
Nao Iguchi, M İrfan Dönmez, Anna P Malykhina, Alonso Carrasco, Duncan T Wilcox
Posterior urethral valves are the most common cause of partial bladder outlet obstruction (PBOO) in the pediatric population. Pathological changes in the bladder developed during PBOO are responsible for long-lasting voiding dysfunction in this population despite early surgical interventions. Increasing evidence showed PBOO induces an upregulation of Hypoxia inducible factors (HIFs) and their transcriptional target genes, and they play a role in pathophysiological changes in the obstructed bladders. We hypothesized that blocking HIF pathways can prevent PBOO-induced bladder dysfunction...
August 2, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28763116/urodynamic-characteristics-of-pelvic-lipomatosis-with-glandular-cystitis-patients-correlate-with-morphologic-alterations-of-the-urinary-system-and-disease-severity
#11
Yuke Chen, Yang Yang, Wei Yu, Yunxiang Xiao, Yu Fan, Jihong Duan, Yuan Tang, Jie Jin, Huihui Wang, He Wang, Sainan Zhu, Zhijun Xi, Shiliang Wu
AIMS: To explore urodynamic characteristics and their clinical value in pelvic lipomatosis (PL) patients. METHODS: We reviewed the clinical information of 84 PL patients. A voiding pressure-flow study was used to classify patients into nonoutlet obstruction (NOO), latter-half-section obstruction (LHSO), or whole-section bladder outlet obstruction (BOO) groups. Urinary morphologic features were measured by imaging examination and cystoscopy. RESULTS: A unique LHSO that presented as sudden increasing detrusor pressure (Pdet) and decreasing flow rate in the latter half of voiding was observed for 52...
August 1, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28762694/pelvic-organ-prolapse
#12
REVIEW
Cheryl B Iglesia, Katelyn R Smithling
Pelvic organ prolapse is the descent of one or more of the anterior vaginal wall, posterior vaginal wall, the uterus (cervix), or the apex of the vagina (vaginal vault or cuff scar after hysterectomy). Prevalence increases with age. The cause of prolapse is multifactorial but is primarily associated with pregnancy and vaginal delivery, which lead to direct pelvic floor muscle and connective tissue injury. Hysterectomy, pelvic surgery, and conditions associated with sustained episodes of increased intra-abdominal pressure, including obesity, chronic cough, constipation, and repeated heavy lifting, also contribute to prolapse...
August 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28757770/recent-research-on-the-role-of-urodynamic-study-in-the-diagnosis-and-treatment-of-male-lower-urinary-tract-symptoms-and-urinary-incontinence
#13
REVIEW
Yuan-Hong Jiang, Hann-Chorng Kuo
Although evidence shows that urodynamic study may not improve outcomes, it can be used to evaluate men with lower urinary tract symptoms (LUTSs) which have not been adequately delineated and treated. In young men with LUTS not responding to treatment based on clinical examination, or elderly men with LUTS and incontinence, a complete urodynamic evaluation is mandatory to understand the pathophysiology underlying LUTS, such as bladder outlet obstruction (BOO), detrusor overactivity, and detrusor underactivity...
April 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/28757757/current-consensus-and-controversy-on-the-diagnosis-of-male-lower-urinary-tract-symptoms-benign-prostatic-hyperplasia
#14
REVIEW
Cheng-Ling Lee, Hann-Chorng Kuo
Traditionally, male lower urinary tract symptoms (LUTS) have been considered a synonym for benign prostate hyperplasia (BPH) because most male LUTS develops in aging men. Medical treatment should be the first-line treatment for BPH and surgical intervention should be performed when there are complications or LUTS refractory to medical treatment. Recent investigations have revealed that bladder dysfunction and bladder outlet dysfunction contribute equally to male LUTS. In the diagnosis of LUTS suggestive of BPH (LUTS/BPH), the following questions should be considered: Is there an obstruction? Are the LUTS caused by an enlarged prostate? What are the appropriate tools to diagnose an obstructive BPH? Should patients with LUTS be treated before bladder outlet obstruction is confirmed? This article discusses the current consensus and controversies in the diagnosis of LUTS/BPH...
January 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/28757756/current-consensus-and-controversy-on-the-treatment-of-male-lower-urinary-tract-symptoms-benign-prostatic-hyperplasia
#15
REVIEW
Chun-Hou Liao, Hann-Chorng Kuo
Lower urinary tract symptoms (LUTS) are highly prevalent in men and increase with age. Because LUTS are common among elderly men, they are usually considered synonymous with benign prostatic hyperplasia (BPH). Drugs should be the first-line treatment for BPH and surgical intervention should be performed only when there are complications or LUTS refractory to medical treatment. In addition to medical treatment, several minimally invasive therapies, such as thermal therapy, prostatic lift, laser evaporation, or laser enucleation techniques have been developed...
January 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/28754926/videourodynamic-studies-of-women-with-voiding-dysfunction
#16
Sheng-Mou Hsiao, Ho-Hsiung Lin, Hann-Chorng Kuo
This retrospective study is aimed to present videourodynamic findings of women with symptoms of voiding dysfunction in a medical center. Of 1914 women, the diagnoses included bladder outlet obstruction (BOO, n = 810, 42.3%), bladder dysfunction (n = 1,048, 54.8%) and normal tracings (n = 56, 2.9%). Anatomic BOO (n = 49) included cystocele (n = 19) and urethral stricture (n = 30). Common functional BOOs included dysfunctional voiding (n = 325, 17.0%) and poor relaxation of the external sphincter (n = 336, 17...
July 28, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28748746/long-term-urodynamic-findings-following-radical-prostatectomy-and-salvage-radiotherapy
#17
Maria Ervandian, Jens Christian Djurhuus, Morten Høyer, Charlotte Graugaard-Jensen, Michael Borre
OBJECTIVE: Lower urinary tract symptoms (LUTS) are common following radical prostatectomy (RP) or intended curative radiotherapy in prostate cancer patients. One-quarter of those treated with RP experience biochemical failure and are subsequently offered salvage radiotherapy (SRT) to the prostatic bed. The aim of this study was to elucidate long-term LUTS after surgery and SRT. MATERIALS AND METHODS: Urodynamic parameters from 16 patients treated with RP and subsequent SRT in the period 2000-2010 were evaluated with uroflowmetry, filling cystometry, pressure-flow and urethral pressure profile (UPP)...
July 27, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28745805/tac-302-promotes-neurite-outgrowth-of-isolated-peripheral-neurons-and-prevents-bladder-denervation-related-bladder-dysfunctions-following-bladder-outlet-obstruction-in-rats
#18
Shohei Yoshida, Naoki Orimoto, Hiroshi Tsukihara, Takahisa Noma, Atsushi Hakozaki, Eiji Sasaki
AIMS: To evaluate the ability of TAC-302, a cyclohexenoic fatty alcohol derivative, to enhance neurite outgrowth in cultured rat dorsal root ganglion (DRG) neurons, and the preventive effects of TAC-302 on bladder denervation-related storage and voiding dysfunctions in rats with bladder outlet obstruction (BOO). METHODS: Rat DRG neurons were cultured in the presence of TAC-302. Cell numbers and neurite lengths were quantified after a 24 h culture. BOO was achieved by partial ligature of the proximal urethra in female rats...
July 26, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28735019/1-year-surgical-outcomes-of-complete-or-incomplete-enucleation-of-prostate-by-monopolar-electrocoagulation-photoselective-vapoenucleation-of-120w-greenlight-laser-and-holmium-laser
#19
Sung Yong Cho, Juhyun Park, Sangjun You, Min Chul Cho, Hyeon Jeong, Hwancheol Son
OBJECTIVE: To evaluate surgical outcomes of patients who underwent complete or incomplete enucleation technique during a short-term postoperative period METHODS: Patients having intractable LUTS/BPH and prostates > 30 grams with obstructed pattern in the urodynamic examinations were included. They underwent TUR-P, 120 W greenlight laser HPS-PVEP, or HoLEP. Patients with the size of remnant prostates minus surgical defects < 25 grams were grouped into the completely enucleated group (group C) and other were group into the partially enucleated group (group P)...
July 19, 2017: Urology
https://www.readbyqxmd.com/read/28730405/non-neurogenic-chronic-urinary-retention-what-are-we-treating
#20
REVIEW
John T Stoffel
PURPOSE OF REVIEW: This review examines current terminology used to define non-neurogenic chronic urinary retention (CUR), describes the pathophysiology of urinary retention, and highlights contemporary diagnostic and treatment algorithms. RECENT FINDINGS: There is no standardized definition for the condition, but volumes >300 ml are commonly used to describe CUR. It is a clinical diagnosis which does not require urodynamics. Pathophysiologic causes of CUR be from myogenic, neurogenic, bladder outlet obstruction, or a combination of these sources...
September 2017: Current Urology Reports
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