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https://www.readbyqxmd.com/read/28430035/noninvasive-neuromodulation-and-thalamic-mapping-with-low-intensity-focused-ultrasound
#1
Robert F Dallapiazza, Kelsie F Timbie, Stephen Holmberg, Jeremy Gatesman, M Beatriz Lopes, Richard J Price, G Wilson Miller, W Jeffrey Elias
OBJECTIVE Ultrasound can be precisely focused through the intact human skull to target deep regions of the brain for stereotactic ablations. Acoustic energy at much lower intensities is capable of both exciting and inhibiting neural tissues without causing tissue heating or damage. The objective of this study was to demonstrate the effects of low-intensity focused ultrasound (LIFU) for neuromodulation and selective mapping in the thalamus of a large-brain animal. METHODS Ten Yorkshire swine ( Sus scrofa domesticus) were used in this study...
April 21, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28429603/effect-of-high-flow-nasal-cannula-oxygen-therapy-versus-conventional-oxygen-therapy-and-noninvasive-ventilation-on-reintubation-rate-in-adult-patients-after-extubation-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#2
Hua-Wei Huang, Xiu-Mei Sun, Zhong-Hua Shi, Guang-Qiang Chen, Lu Chen, Jan O Friedrich, Jian-Xin Zhou
PURPOSE: We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the effect of high-flow nasal cannula (HFNC) on reintubation in adult patients. PROCEDURES: Ovid Medline, Embase, and Cochrane Database of Systematic Reviews were searched up to November 1, 2016, for RCTs comparing HFNC versus conventional oxygen therapy (COT) or noninvasive ventilation (NIV) in adult patients after extubation. The primary outcome was reintubation rate, and the secondary outcomes included complications, tolerance and comfort, time to reintubation, length of stay, and mortality...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28428038/non-invasive-tracking-of-hydrogel-degradation-using-upconversion-nanoparticles
#3
Yuqing Dong, Guorui Jin, Changchun Ji, Rongyan He, Min Lin, Xin Zhao, Ang Li, Tian Jian Lu, Feng Xu
Tracking the distribution and degradation of hydrogels in vivo is important for various applications including tissue engineering and drug delivery. Among various imaging modalities, fluorescence imaging has attracted intensive attention due to their high sensitivity, low cost and easy operation. Particularly, upconversion nanoparticles (UCNPs) that emit visible lights upon near-infrared (NIR) light excitation as tracking probes are promising in deciphering the fate of hydrogels after transplantation. Herein, we reported a facile and non-invasive in vivo hydrogel tracking method using UCNPs, where the degradation of hydrogels was determined using the decrease in fluorescence intensity from the UCNPs encapsulated in the hydrogels...
April 17, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28427534/methodologies-for-the-characterization-of-the-quality-of-dairy-products
#4
Romdhane Karoui
The growing interest of consumers in food quality and safety issues has contributed to the increasing demand for sensitive and rapid analytical technologies. Physicochemical, textural, sensory, etc., methods have been used to evaluate the quality and authenticity of milk and dairy products. Despite the importance of these standard methods, they are expensive and time consuming. Recently, spectroscopic methods have shown great potential due to speed of analysis, minimal sample preparation, high repeatability, low cost, and, most of all, the fact that these techniques are noninvasive and nondestructive and, therefore, could be applied to any on-line monitoring system...
2017: Advances in Food and Nutrition Research
https://www.readbyqxmd.com/read/28427298/recent-advances-in-pediatric-gastrointestinal-endoscopy-an-overview
#5
Salvatore Oliva, Salvatore Cucchiara, Stanley Allen Cohen
Pediatric gastrointestinal endoscopy has become a fundamental component of health care for infants and children. New imaging technologies and creative extraluminal applications have brought exciting and clinically important benefits to pediatric gastrointestinal endoscopy. Areas covered: The impact of different new technologies in pediatric endoscopy and focused on improvements in mucosa visualization and the application of new noninvasive tools and procedures to avoid biopsies or surgery are reviewed. Expert commentary: Enhancement in mucosal visualization and reduction of anesthesia and biopsies are the main goals that guide the endoscopy development in pediatrics...
April 20, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28427056/blood-pressure-during-the-immediate-neonatal-transition-is-the-mean-arterial-blood-pressure-relevant-for-the-cerebral-regional-oxygenation
#6
Nariae Baik, Berndt Urlesberger, Bernhard Schwaberger, Alexander Avian, Lukas Mileder, Georg M Schmölzer, Gerhard Pichler
BACKGROUND: Measurement of mean arterial blood pressure (MABP) is feasible during neonatal transition. OBJECTIVE: The objective of this study was to investigate a potential influence of MABP on the cerebral regional oxygen saturation (crSO2) in preterm and term infants during the immediate neonatal transition. MATERIALS AND METHODS: Preterm and term infants were included in this observational study. The crSO2 was measured by near-infrared spectroscopy with the INVOS 5100C (Somanetics Corp...
April 21, 2017: Neonatology
https://www.readbyqxmd.com/read/28426506/applications-of-noninvasive-hemodynamic-monitoring-in-obstetric-management
#7
John T Sullivan
Clinicians managing obstetric patients are dependent on valid hemodynamic measurements to guide care. Heart rate and noninvasive blood pressure guide most current care. New hemodynamic monitors are being used to report research findings and are being investigated by clinicians for their value to supplement standard monitoring. These include arterial pulse contour analysis, Doppler velocimetry, and bioimpedance among others. This chapter serves to present these new devices with a critical review of their advantages and limitations, and most importantly the validity of their measurements...
June 2017: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28421189/optic-nerve-sheath-diameter-ultrasound-evaluation-in-intensive-care-unit-possible-role-and-clinical-aspects-in-neurological-critical-patients-daily-monitoring
#8
M Toscano, G Spadetta, P Pulitano, M Rocco, V Di Piero, O Mecarelli, E Vicenzini
Background. The increase of the optic nerve sheath diameter (ONSD) is a reliable, noninvasive sonographic marker of intracranial hypertension. Aim of the study was to demonstrate the efficacy of ONSD evaluation, when monitoring neurocritical patients, to early identify malignant intracranial hypertension in patients with brain death (BD). Methods. Data from ultrasound ONSD evaluation have been retrospectively analyzed in 21 sedated critical patients with neurological diseases who, during their clinical course, developed BD...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28420362/clinical-hemispheric-and-autonomic-changes-associated-with-use-of-closed-loop-allostatic-neurotechnology-by-a-case-series-of-individuals-with-self-reported-symptoms-of-post-traumatic-stress
#9
Charles H Tegeler, Jared F Cook, Catherine L Tegeler, Joshua R Hirsch, Hossam A Shaltout, Sean L Simpson, Brian C Fidali, Lee Gerdes, Sung W Lee
BACKGROUND: The objective of this pilot study was to explore the use of a closed-loop, allostatic, acoustic stimulation neurotechnology for individuals with self-reported symptoms of post-traumatic stress, as a potential means to impact symptomatology, temporal lobe high frequency asymmetry, heart rate variability (HRV), and baroreflex sensitivity (BRS). METHODS: From a cohort of individuals participating in a naturalistic study to evaluate use of allostatic neurotechnology for diverse clinical conditions, a subset was identified who reported high scores on the Posttraumatic Stress Disorder Checklist (PCL)...
April 19, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28420215/a-phonocardiographic-based-fiber-optic-sensor-and-adaptive-filtering-system-for-noninvasive-continuous-fetal-heart-rate-monitoring
#10
Radek Martinek, Jan Nedoma, Marcel Fajkus, Radana Kahankova, Jaromir Konecny, Petr Janku, Stanislav Kepak, Petr Bilik, Homer Nazeran
This paper focuses on the design, realization, and verification of a novel phonocardiographic- based fiber-optic sensor and adaptive signal processing system for noninvasive continuous fetal heart rate (fHR) monitoring. Our proposed system utilizes two Mach-Zehnder interferometeric sensors. Based on the analysis of real measurement data, we developed a simplified dynamic model for the generation and distribution of heart sounds throughout the human body. Building on this signal model, we then designed, implemented, and verified our adaptive signal processing system by implementing two stochastic gradient-based algorithms: the Least Mean Square Algorithm (LMS), and the Normalized Least Mean Square (NLMS) Algorithm...
April 18, 2017: Sensors
https://www.readbyqxmd.com/read/28419403/adaptive-optics-of-small-choroidal-melanoma
#11
Murilo W Rodrigues, Emil A Say, Carol L Shields, Rodrigo Jorge
The authors report the use of an adaptive optics (AO) system in an asymptomatic patient with small choroidal melanoma. A noninvasive, novel assessment that detected potential photoreceptor abnormalities in the retina overlying the choroidal lesion and adjacent retina is presented. These findings may help current clinical evaluation to monitor structural damage to the outer retina and possibly justify earlier intervention in borderline cases. Future research is warranted to recognize full potential of this imaging modality...
April 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28418937/clinical-validation-of-a-new-wrist-continuous-noninvasive-hemodynamic-monitoring-system-in-comparison-with-invasive-radial-artery-measurement
#12
Chen Li, Chanjuan Li, Wei Zhang, Ling Wang, Zhidong Wang, Yongji Wang, Jielai Xia
BACKGROUND: An ideal arterial pressure monitoring system for perioperative care is required to be accurate, noninvasive, continuous, and risk free. Although several continuous noninvasive arterial pressures (CNAP) are determined on the finger, a new wrist CNAP monitoring system was developed. This prospective study was designed as a randomized-controlled trial to assess its validity in comparison with invasive arterial pressure (IAP) monitoring. PATIENTS AND METHODS: Sixty patients undergoing elective surgery under general anesthesia were enrolled...
April 17, 2017: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/28417345/imaging-markers-for-monitoring-disease-activity-in-multiple-sclerosis
#13
REVIEW
Suradech Suthiphosuwan, David Kim, Aditya Bharatha, Jiwon Oh
Multiple sclerosis (MS) is an immune-mediated disease affecting the central nervous system (CNS). Magnetic resonance imaging (MRI) has long been recognized as an important tool in the diagnosis of MS. It is increasingly recognized that in addition to its role in diagnosis, MRI can play a key role as a noninvasive tool for prognostication, disease monitoring, assessment of treatment efficacy, and safety monitoring of disease-modifying therapies (DMTs). A confluence of factors, including increased availability of MRI, development of improved MRI techniques, and increased availability of DMTs have contributed to the expanding role of MRI in MS clinical care...
May 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/28416667/autonomous-sweat-extraction-and-analysis-applied-to-cystic-fibrosis-and-glucose-monitoring-using-a-fully-integrated-wearable-platform
#14
Sam Emaminejad, Wei Gao, Eric Wu, Zoe A Davies, Hnin Yin Yin Nyein, Samyuktha Challa, Sean P Ryan, Hossain M Fahad, Kevin Chen, Ziba Shahpar, Salmonn Talebi, Carlos Milla, Ali Javey, Ronald W Davis
Perspiration-based wearable biosensors facilitate continuous monitoring of individuals' health states with real-time and molecular-level insight. The inherent inaccessibility of sweat in sedentary individuals in large volume (≥10 µL) for on-demand and in situ analysis has limited our ability to capitalize on this noninvasive and rich source of information. A wearable and miniaturized iontophoresis interface is an excellent solution to overcome this barrier. The iontophoresis process involves delivery of stimulating agonists to the sweat glands with the aid of an electrical current...
April 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28415647/contrast-agents-in-dynamic-contrast-enhanced-magnetic-resonance-imaging
#15
REVIEW
Yuling Yan, Xilin Sun, Baozhong Shen
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a noninvasive method to assess angiogenesis, which is widely used in clinical applications including diagnosis, monitoring therapy response and prognosis estimation in cancer patients. Contrast agents play a crucial role in DCE-MRI and should be carefully selected in order to improve accuracy in DCE-MRI examination. Over the past decades, there was much progress in the development of optimal contrast agents in DCE-MRI. In this review, we describe the recent research advances in this field and discuss properties of contrast agents, as well as their advantages and disadvantages...
March 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28415600/the-value-of-mri-in-evaluating-the-efficacy-and-complications-with-the-treatment-of-intra-arterial-chemotherapy-for-retinoblastoma
#16
Shuxian Chen, Xunda Ji, Ming Liu, Zhengrong Xia, Hui Zheng, Qiufeng Yin, He Wang, Yuhua Li
Retinoblastoma is the most common intraocular malignant tumor of childhood. Intra-arterial chemotherapy (IAC) is a recently popularized technique used for the treatment of retinoblastoma, to decrease mortality, increase preservation of the eye, and prevent blindness. Along with the extensive use of IAC, it is important to apply noninvasive examination methods to assess the activity of the tumor and the risk factors for disease dissemination without histopathological confirmation. There are few studies that have assessed the value of magnetic resonance imaging (MRI) in evaluating the efficacy and complications of IAC for retinoblastoma...
March 21, 2017: Oncotarget
https://www.readbyqxmd.com/read/28413641/serum-mir-20a-is-a-promising-biomarker-for-gastric-cancer
#17
Ruirui Yang, Yun Fu, Ying Zeng, Mengqin Xiang, Yufang Yin, Li Li, Haifan Xu, Jing Zhong, Xi Zeng
Gastric cancer (GC) is a common type of cancer, particularly in China. Numerous studies have demonstrated that circulating microRNAs (miRNAs) have potential applications as noninvasive biomarkers for cancer diagnosis and prognosis. Microarray-based serum miRNA profiling was performed on the serum of 12 paired pre- and post-operative GC patients to screen differentially expressed serum miRNAs. Twelve different serum miRNAs between pre- and post-operative GC patients were identified. Those miRNAs were verified by real-time quantitative polymerase chain reaction in 110 paired pre- and post-operative serum samples from 55 GC patients...
April 2017: Biomedical Reports
https://www.readbyqxmd.com/read/28413621/recent-advances-in-pediatric-ventilatory-assistance
#18
REVIEW
Nicolas Nardi, Guillaume Mortamet, Laurence Ducharme-Crevier, Guillaume Emeriaud, Philippe Jouvet
In this review on respiratory assistance, we aim to discuss the following recent advances: the optimization and customization of mechanical ventilation, the use of high-frequency oscillatory ventilation, and the role of noninvasive ventilation. The prevention of ventilator-induced lung injury and diaphragmatic dysfunction is now a key aspect in the management of mechanical ventilation, since these complications may lead to higher mortality and prolonged length of stay in intensive care units. Different physiological measurements, such as esophageal pressure, electrical activity of the diaphragm, and volumetric capnography, may be useful objective tools to help guide ventilator assistance...
2017: F1000Research
https://www.readbyqxmd.com/read/28413489/retrospective-review-of-epidemic-viral-pneumonia-cases-in-turkey-a-multicenter-study
#19
Mustafa Çörtük, Murat Acat, Onur Yazici, Zehra Yasar, Kemal Kiraz, Sena Yapicioglu Ataman, Elif Tanriverdi, Burcak Zitouni, Cenk Kirakli, Ozlem Ediboglu, Fevziye Tuksavul, Adem Dirican, Hale Kefeli Celik, Sevket Ozkaya, Erdogan Cetinkaya
Influenza A (H1N1) caused its first pandemic in 2009 in USA and Mexico. Since then, clinicians have exercised great care in order to make an early diagnosis of viral pneumonias. This is due in part to pandemic influenza A infection having greater impact on populations <65 years old than other viral strains, including seasonal influenza. Chest radiographies of those affected displayed a rapid progression of patchy infiltrates, and a large proportion of individuals required admission to intensive care units (ICU)...
April 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28410347/accuracy-of-zero-heat-flux-cutaneous-temperature-in-intensive-care-adults
#20
Claire Dahyot-Fizelier, Solène Lamarche, Thomas Kerforne, Thierry Bénard, Benoit Giraud, Rémy Bellier, Elsa Carise, Denis Frasca, Olivier Mimoz
OBJECTIVES: To compare accuracy of a continuous noninvasive cutaneous temperature using zero-heat-flux method to esophageal temperature and arterial temperature. DESIGN: Prospective study. SETTING: ICU and NeuroICU, University Hospital. PATIENTS: Fifty-two ICU patients over a 4-month period who required continuous temperature monitoring were included in the study, after informed consent. INTERVENTIONS: All patients had esophageal temperature probe and a noninvasive cutaneous device to monitor their core temperature continuously...
April 13, 2017: Critical Care Medicine
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