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https://www.readbyqxmd.com/read/28207915/suicidal-and-death-ideation-among-adults-with-obsessive-compulsive-disorder-presenting-for-intensive-intervention
#1
Eric A Storch, Brian Kay, Monica S Wu, Joshua M Nadeau, Bradley Riemann
BACKGROUND: This study examined the frequency and relation of death and/or suicidal ideation to treatment response in 101 adults with obsessive-compulsive disorder (OCD) presenting for intensive intervention. METHODS: Within 2 days of admission to an intensive treatment program, 101 adults with OCD completed the Yale-Brown Obsessive Compulsive Scale-Self Report, Quick Inventory of Depressive Symptomatology-Self Report, Intolerance of Uncertainty Scale, Obsessive-Compulsive Inventory-Revised, Penn State Worry Questionnaire, and Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form, and were administered the Columbia Suicide Scale by a trained clinician...
February 2017: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
https://www.readbyqxmd.com/read/28194835/mindfulness-based-cognitive-therapy-as-an-augmentation-treatment-for-obsessive-compulsive-disorder
#2
Brenda L Key, Karen Rowa, Peter Bieling, Randi McCabe, Elizabeth J Pawluk
: A significant number of obsessive-compulsive disorder (OCD) patients continue to experience symptoms that interfere with their functioning following cognitive behavioural therapy (CBT). Providing an additional augmentation treatment following CBT could help reduce these residual symptoms. Mindfulness interventions that facilitate less reactivity to thoughts and feelings may be helpful for patients suffering from residual OCD symptoms. The purpose of the current randomized waitlist control trial was to evaluate the feasibility and impact of providing an 8-week mindfulness-based cognitive therapy (MBCT) intervention following completion of a CBT intervention to OCD patients who continued to suffer from significant symptoms...
February 13, 2017: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/28183286/register-based-study-of-the-incidence-comorbidities-and-demographics-of-obsessive-compulsive-disorder-in-specialist-healthcare
#3
Hanna Rintala, Roshan Chudal, Sami Leppämäki, Susanna Leivonen, Susanna Hinkka-Yli-Salomäki, Andre Sourander
BACKGROUND: Incidence of obsessive-compulsive disorder (OCD) has been suspected to increase but nationwide epidemiological studies are limited. This study aims to examine sex-specific incidence time trends and characterize psychiatric and neurodevelopmental comorbidities and sociodemographic risk factors of OCD in specialist healthcare in Finland. METHODS: A nationwide register-based study using data from four Finnish registers identified 3372 OCD cases and 13,372 matched controls (1:4)...
February 10, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28161615/what-do-spanish-adolescents-think-about-obsessive-compulsive-disorder-mental-health-literacy-and-stigma-associated-with-symmetry-order-and-aggression-related-symptoms
#4
Gemma García-Soriano, María Roncero
Obsessive-compulsive disorder (OCD) is a frequent and disabling disorder with a long delay in seeking help that could partly be due to poor mental health literacy and stigmatizing attitudes. This study analyzes the mental health literacy and stigma associated with symmetry/order and aggression-related OCD in a Spanish adolescent sample. This age group was chosen because adolescence is a vulnerable period for the development of OCD, and adolescents are often reluctant to seek professional help. One hundred and two non-clinical adolescents read two vignettes describing symmetry/order and aggression-related OCD...
January 31, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28160276/harm-avoidance-and-childhood-adversities-in-patients-with-obsessive-compulsive-disorder-and-their-unaffected-first-degree-relatives
#5
K Bey, L Lennertz, A Riesel, J Klawohn, C Kaufmann, S Heinzel, R Grützmann, N Kathmann, M Wagner
OBJECTIVE: The etiology of obsessive-compulsive disorder (OCD) is assumed to involve interactions between genetically determined vulnerability factors and significant environmental features. Here, we aim to investigate how the personality trait harm avoidance and the experience of childhood adversities contribute to OCD. METHOD: A total of 169 patients with OCD, 157 healthy comparison subjects, and 57 unaffected first-degree relatives of patients with OCD participated in the study...
February 3, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28154539/temporal-association-of-certain-neuropsychiatric-disorders-following-vaccination-of-children-and-adolescents-a-pilot-case-control-study
#6
Douglas L Leslie, Robert A Kobre, Brian J Richmand, Selin Aktan Guloksuz, James F Leckman
BACKGROUND: Although the association of the measles, mumps, and rubella vaccine with autism spectrum disorder has been convincingly disproven, the onset of certain brain-related autoimmune and inflammatory disorders has been found to be temporally associated with the antecedent administration of various vaccines. This study examines whether antecedent vaccinations are associated with increased incidence of obsessive-compulsive disorder (OCD), anorexia nervosa (AN), anxiety disorder, chronic tic disorder, attention deficit hyperactivity disorder, major depressive disorder, and bipolar disorder in a national sample of privately insured children...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28151703/the-child-behavior-checklist-obsessive-compulsive-subscale-detects-severe-psychopathology-and-behavioral-problems-among-school-aged-children
#7
Laura O Saad, Maria C do Rosario, Raony C Cesar, Marcelo C Bastituzzo, Marcelo Q Hoexter, Gisele G Manfro, Roseli G Shavitt, James F Leckman, Eurípedes C Miguel, Pedro G Alvarenga
OBJECTIVE: The aims of this study were (1) to assess obsessive-compulsive symptoms (OCS) dimensionally in a school-aged community sample and to correlate them with clinical and demographical variables; (2) to determine a subgroup with significant OCS ("at-risk for OCD") using the Child Behavior Checklist (CBCL-OCS) and (3) to compare it with the rest of the sample; (4) To review the CBCL-OCS subscale properties as a screening tool for pediatric OCD. METHODS: Data from the Brazilian High Risk Cohort were analyzed...
February 2, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28137336/a-pilot-investigation-of-cognitive-behavioural-therapy-for-clinical-perfectionism-in-obsessive-compulsive-disorder
#8
Shalane K Sadri, Rebecca A Anderson, Peter M McEvoy, Robert T Kane, Sarah J Egan
BACKGROUND: Perfectionism is strongly associated with obsessive compulsive disorder (OCD). Cognitive behavioural therapy for perfectionism (CBT-P) has been found to result in reductions in a range of symptoms in individuals with anxiety disorders, depression and eating disorders. AIM: To pilot-test the efficacy of group CBT for perfectionism in participants with OCD and elevated perfectionism. METHOD: Participants were randomized to receive immediate 8-week group CBT-P (n = 4) or an 8-week waitlist followed by CBT-P (n = 7)...
January 31, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28135888/curcumin-for-neuropsychiatric-disorders-a-review-of-in-vitro-animal-and-human-studies
#9
Adrian L Lopresti
Turmeric has been used in traditional medicine for centuries to treat a range of ailments. Its primary active constituent curcumin, can influence an array of biological activities. Many of these, such as its anti-inflammatory, antioxidant, neuroprotective, and monoaminergic effects are dysregulated in several neuropsychiatric disorders. In this systematic review, in vitro, animal, and human studies investigating the potential of curcumin as a treatment for neuropsychiatric disorders such as major depressive disorder, post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), bipolar disorder, psychotic disorders, and autism are reviewed, and directions for future research are proposed...
January 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28096676/aripiprazole-augmentation-in-managing-comorbid-obsessive-compulsive-disorder-and-bipolar-disorder-a-case-with-suicidal-attempts
#10
Jianbo Lai, Qiaoqiao Lu, Peng Zhang, Tingting Xu, Yi Xu, Shaohua Hu
Comorbid obsessive-compulsive disorder (OCD) and bipolar disorder (BD) have long been an intractable problem in clinical practice. The increased risk of manic/hypomanic switch hinders the use of antidepressants for managing coexisting OCD symptoms in BD patients. We herein present a case of a patient with BD-OCD comorbidity, who was successfully treated with mood stabilizers and aripiprazole augmentation. The young female patient reported recurrent depressive episodes and aggravating compulsive behaviors before hospitalization...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28066002/management-of-obsessive-compulsive-disorder-comorbid-with-bipolar-disorder
#11
REVIEW
Firoz Kazhungil, E Mohandas
Obsessive-compulsive disorder (OCD) is one of the most common comorbidities in bipolar disorder (BD). Clinicians often get perplexed in making treatment decisions when encountering comorbid OCD and BD as treatment of OCD by pharmacotherapy may induce or exacerbate mood instability and psychotherapeutic approaches for OCD may not be feasible in acute manic or depressive state of BD. In this study, we reviewed literature, whether existing guideline-based treatments of BD may be effective in OCD and whether newer agents will be of use for treating this comorbidity...
July 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28063400/relationships-between-neuropsychological-variables-and-factor-analysed-symptom-dimensions-in-obsessive-compulsive-disorder
#12
Himani Kashyap, J Keshav Kumar, Thennarasu Kandavel, Y C Janardhan Reddy
Despite mounting evidence for the distinctiveness of symptom dimensions in obsessive-compulsive disorder, neuropsychological studies have been few, focused on small samples, and relying on classification of participants based on mutually exclusive symptom categories, resulting in lack of concordance across neuropsychological and imaging studies. Neuropsychological assessment was undertaken with 150 individuals with DSM IV OCD, and neuropsychological variables were analysed in relation to symptom dimension scores derived from factor analysis...
December 29, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/28052778/co-morbid-obsessive-compulsive-disorder-and-depression-a-bayesian-network-approach
#13
R J McNally, P Mair, B L Mugno, B C Riemann
BACKGROUND: Obsessive-compulsive disorder (OCD) is often co-morbid with depression. Using the methods of network analysis, we computed two networks that disclose the potentially causal relationships among symptoms of these two disorders in 408 adult patients with primary OCD and co-morbid depression symptoms. METHOD: We examined the relationship between the symptoms constituting these syndromes by computing a (regularized) partial correlation network via the graphical LASSO procedure, and a directed acyclic graph (DAG) via a Bayesian hill-climbing algorithm...
January 5, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28041946/hyperactive-performance-monitoring-as-a-transdiagnostic-marker-results-from-health-anxiety-in-comparison-to-obsessive-compulsive-disorder
#14
Anja Riesel, Stefanie Goldhahn, Norbert Kathmann
Hyperactive error-related brain activity has been found in individuals with obsessive-compulsive disorder (OCD), generalized and social anxiety as well as depression and has been proposed as a transdiagnostic marker. The specific phenotype to which it is related is still debated and anxious apprehension, threat sensitivity and checking have been proposed as promising candidates. To validate the idea that hyperactive performance monitoring is shared by anxiety and anxiety-related disorders and to refine our knowledge about its specificity, data from further anxiety and anxiety-related disorders are required...
February 2017: Neuropsychologia
https://www.readbyqxmd.com/read/27995068/shared-white-matter-alterations-across-emotional-disorders-a-voxel-based-meta-analysis-of-fractional-anisotropy
#15
Lisanne Michelle Jenkins, Alyssa Barba, Miranda Campbell, Melissa Lamar, Stewart A Shankman, Alex D Leow, Olusola Ajilore, Scott Aaron Langenecker
BACKGROUND: White matter (WM) integrity may represent a shared biomarker for emotional disorders (ED). Aims: To identify transdiagnostic biomarkers of reduced WM by meta-analysis of findings across multiple EDs. METHOD: Web of Science was searched systematically for studies of whole brain analysis of fractional anisotropy (FA) in adults with major depressive disorder, bipolar disorder, social anxiety disorder, obsessive-compulsive disorder or posttraumatic stress disorder compared with a healthy control (HC) group...
2016: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27994542/the-retrograde-connections-and-anatomical-segregation-of-the-g%C3%A3-ttingen-minipig-nucleus-accumbens
#16
Anders C Meidahl, Dariusz Orlowski, Jens C H Sørensen, Carsten R Bjarkam
Nucleus accumbens (NAcc) has been implicated in several psychiatric disorders such as treatment resistant depression (TRD), and obsessive-compulsive disorder (OCD), and has been an ongoing experimental target for deep brain stimulation (DBS) in both rats and humans. In order to translate basic scientific results from rodents to the human setting a large animal model is needed to thoroughly study the effect of such therapeutic interventions. The aim of the study was, accordingly, to describe the basic anatomy of the Göttingen minipig NAcc and its retrograde connections...
2016: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/27988419/health-anxiety-in-obsessive-compulsive-disorder-and-obsessive-compulsive-symptoms-in-severe-health-anxiety-an-investigation-of-symptom-profiles
#17
Erik Hedman, Brjánn Ljótsson, Erland Axelsson, Gerhard Andersson, Christian Rück, Erik Andersson
Severe health anxiety (SHA) shares features with obsessive-compulsive disorder (OCD) and in recent years there has been a debate as to whether the two disorders may represent two facets of the same condition. Few studies have however investigated the overlap and differences in symptom profiles between the disorders. The primary aim of the present study was to investigate these aspects using one sample of participants with a principal diagnosis of SHA and one sample of participants with a principal OCD diagnosis...
January 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/27979316/seasonal-mood-changes-in-patients-with-obsessive-compulsive-disorder
#18
Oğuz Tan, Barış Metin, Barış Önen Ünsalver, Gökben Hızlı Sayar
Obsessive-compulsive disorder (OCD) is frequently associated with mood disorders. However, to date, the co-occurrence of OCD with seasonal affective disorder (SAD) has not been investigated. We have aimed to estimate the prevalence of seasonal mood changes in patients with OCD and explore the contribution of seasonality in mood to the severity of OCD. The Seasonal Pattern Assessment Questionnaire (SPAQ), the Yale-Brown Obsession and Compulsion Scale (Y-BOCS), the Hamilton Depression Rating Scale-17 Items (HDRS-17), and the Beck Anxiety Inventory (BAI) were administered to patients with OCD (n=104) and controls (n=125)...
June 16, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27939647/intolerance-of-uncertainty-not-just-right-experiences-and-compulsive-checking-test-of-a-moderated-mediation-model-on-a-non-clinical-sample
#19
Gioia Bottesi, Marta Ghisi, Claudio Sica, Mark H Freeston
OBJECTIVE: Intolerance of uncertainty (IU) and not just right experiences (NJREs) have been claimed putative vulnerability factors for obsessive-compulsive disorder (OCD). The aim of the present study was to test whether IU could represent a trans-diagnostic construct accountable for OC checking behaviors and whether NJREs could embody an OCD-specific criterion through which IU operates. METHOD: One hundred and eighty-eight Italian community individuals completed self-report measures of IU, NJREs, OC symptoms, worry, anxiety, and depression...
December 2, 2016: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/27937062/cognitive-flexibility-in-juvenile-anorexia-nervosain-relation-to-comorbid-symptoms-of-depression-obsessive-compulsive-symptoms-and-duration-of-illness
#20
Anne Rößner, Izabela Juniak, Betteke Maria van Noort, Ernst Pfeiffer, Ulrike Lehmkuhl, Viola Kappel
OBJECTIVE: Whereas the evidence in adolescents is inconsistent, anorexia nervosa (AN) in adults is characterized by weak cognitive flexibility. This study investigates cognitive flexibility in adolescents with AN and its potential associations with symptoms of depression, obsessive compulsive disorder (OCD), and duration of illness. METHODS: 69 patients and 63 age-matched healthy controls (HC) from 9 till 19 years of age were assessed using the Trail-Making Test (TMT) and self-report questionnaires...
December 12, 2016: Zeitschrift Für Kinder- und Jugendpsychiatrie und Psychotherapie
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