Peng Sun, Yusong Luan, Xuhao Cai, Qi Liu, Peide Ren, Pengpan Xin, Yonggang Yu, Bolun Song, Yangyang Wang, Huijing Chang, Haoyue Ma, Yinggang Chen
Colorectal cancer (CRC), also known as colon cancer, is the third most common cancer and the fourth most cause of cancer-related death in the world. CRC can be classified into two major subtypes, including microsatellite instability (MSI) and microsatellite stability (MSS), which showed different characteristics in immunotherapy. Low sensitivity of diagnostic biomarkers and metastasis are still the principal cause of mortality, especially in MSI. Here, applying computational programs, we identified recurring expression programs based on single cell RNA sequencing (scRNA-Seq) data of CRC cell lines...
March 30, 2024: Heliyon