keyword
MENU ▼
Read by QxMD icon Read
search

Albendazole

keyword
https://www.readbyqxmd.com/read/28336270/the-natural-history-of-cystic-echinococcosis-in-untreated-and-albendazole-treated-patients
#1
N Solomon, M Kachani, E Zeyhle, C N L Macpherson
The World Health Organization (WHO) treatment protocols for cystic echinococcosis (CE) are based on the standardized ultrasound (US) classification. This study examined whether the classification reflected the natural history of CE in untreated and albendazole-treated patients. Data were collected during mass US screenings in CE endemic regions among transhumant populations, the Turkana and Berber peoples of Kenya and Morocco. Cysts were classified using the WHO classification. Patient records occurring prior to treatment, and after albendazole administration, were selected...
March 20, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28325339/toward-novel-antiparasitic-formulations-complexes-of-albendazole-desmotropes-and-%C3%AE-cyclodextrin
#2
Ana K Chattah, Laura Y Pfund, Ariana Zoppi, Marcela R Longhi, Claudia Garnero
Novel complexes of two different solid forms of Albendazol and β-cyclodextrin were investigated in an attempt to obtain promising candidates for the preparation of alternative matrices used in pharmaceutical oral formulations. The interaction between each form of Albendazol and β-cyclodextrin was studied in solution and solid state, in order to investigate their effect on the solubility and dissolution rate of Albendazol solid forms. The solid supramolecular systems were characterized using a variety of techniques including natural-abundance (13)C cross-polarization magic-angle-spinning nuclear magnetic resonance, powder X-ray diffraction, Fourier transform-infrared spectroscopy and scanning electron microscopy...
May 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28324468/ascariasis-and-hyperosmolar-hyperglycemic-state-a-surprising-ultrasound-finding-in-the-emergency-department
#3
Giles N Cattermole, Jean-Paul Nzabandora
BACKGROUND: We report the ultrasound finding of ascariasis in a patient with hyperosmolar hyperglycemic state (HHS). Although ascariasis is common in low-resource settings, there has been no previous report associating ascariasis with HHS. CASE PRESENTATION: A 26-year-old Rwandan man was admitted to the emergency department in coma, with a glycemia of 600 mg/dl. He was resuscitated with fluids, intubated and ventilated, and treated with insulin and antibiotics...
December 2017: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28320391/quantification-of-resistant-alleles-in-the-%C3%AE-tubulin-gene-of-field-strains-of-gastrointestinal-nematodes-and-their-relation-with-the-faecal-egg-count-reduction-test
#4
Myriam Esteban-Ballesteros, Francisco A Rojo-Vázquez, Philip J Skuce, Lynsey Melville, Camino González-Lanza, María Martínez-Valladares
BACKGROUND: Benzimidazole (BZ) resistance in gastrointestinal nematodes is associated with a single nucleotide polymorphism (SNP) at codons 167, 198 and 200 in the isotype 1 of beta-tubulin gene although in some species these SNPs have also been associated with resistance to macrocyclic lactones. In the present study we compared the levels of resistance in Teladorsagia circumcincta and Trichostrongylus colubriformis by means of the faecal egg reduction test (FECRT) and the percentage of resistant alleles obtained after pyrosequencing...
March 20, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28319358/albendazole-therapy-in-human-lung-and-liver-hydatid-cysts-a-13-year-experience
#5
Seyed Hossein Fattahi Masoom, Shahrzad Mohammadzadeh Lari, Asieh Sadat Fattahi, Negin Ahmadnia, Mahla Rajabi, Maliheh NaderiKalat
BACKGROUND: Cystic echinococcosis (CE) is an endemic disease in Iran. This study has aimed to report the efficacy of Albendazole therapy in patients with CE. METHOD: Among 164 patients with echinococcosis who were referred to the surgery clinic, Ghaem hospital, Mashhad University of Medical Sciences between 2001 and 2013, two were diagnosed with alveolar echinococcosis (AE) and 162 with CE; 43 of whom underwent surgery. The rest 119 patients received medical therapy by Albendazole 15 mg/kg/day for three phases...
March 20, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28316382/effect-of-punica-granatum-fruit-peel-on-glucose-6-phosphate-dehydrogenase-and-malate-dehydrogenase-in-amphistome-gastrothylax-indicus
#6
Rama Aggarwal, Upma Bagai
Increasing anthelmintic resistance and the impact of conventional anthelmintics on the environment, it is important to look for alternative strategies against helminth parasite in sheep. Important lipogenic enzymes like glucose-6-phosphate dehydrogenase (G-6-PDH) and malate dehydrogenase (MDH) show subcellular distribution pattern. Activity of G-6-PDH was largely restricted to cytosolic fraction while MDH was found in both cytosolic and mitochondrial fraction in Gastrothylax indicus. Following in vitro treatment with ethanolic and aqueous extracts of Punica granatum fruit peel and commercial anthelmintic, albendazole G-6-PDH activity was decreased by 19-32 %, whereas MDH was suppressed by 24-41 %, compared to the respective control...
March 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28301809/evaluation-of-drug-uptake-and-deactivation-in-plant-fate-of-albendazole-in-ribwort-plantain-plantago-laceolata-cells-and-regenerants
#7
Lucie Stuchlíková Raisová, Radka Podlipná, Barbora Szotáková, Eliška Syslová, Lenka Skálová
Albendazole (ABZ) is a benzimidazole anthelmintic widely used especially in veterinary medicine. Along with other drugs, anthelmintics have become one of a new class of micro-pollutants that disturb the environment but the information about their fate in plants remains limited. The present study was designed to test the uptake and biotransformation of ABZ in the ribwort plantain (Plantago lancelota), a common meadow plant, which can come into contact with this anthelmintic through the excrements of treated animals in pastures...
March 13, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28299767/huge-renal-hydatid-cyst-an-unusual-presentation-a-case-report
#8
Jamal Jafari Nodoushan, Samad Zare, Seyed Mostafa Tabatabaei, Mojtaba Babaei Zarch, Fatemeh Imani, Fatemeh Ehsani
Isolated renal hydatid cyst is a rare entity accounting for only 2-4% of cases. A 60-year-old male presented to our clinic complaining of pain in right flank. He had a history of eating raw sheep liver. Imaging revealed an expansive cystic mass measuring approximately300×180 mm in the right side of abdomen. The patient was treated by open surgery in combination with perioperative chemotherapy with albendazol. In this case, we reported an unusual presentation of hydatid cyst disease. Physicians should be aware of its clinical presentations and complications...
March 16, 2017: Urology Journal
https://www.readbyqxmd.com/read/28283015/-cutaneous-larva-migrans-in-turkey-an-imported-case-report
#9
Meliha Çağla Sönmezer, Şebnem Erdinç, Necla Tülek, Cahit Babür, Ayşe Büyükdemirci, Tuba İlgar, Günay Ertem
Cutaneous larva migrans (CLM) is a parasitic infection most commonly found in tropical and subtropical areas. However, with the ease and increase of foreign travel to many countries around the world, the infection is not limited to these areas. CLM is an erythematous, serpiginous infection with skin eruption caused by percutaneous penetration of the larvae to the skin. In this report, a case diagnosed as imported CLM after an Amazon trip and treated with albendazole was presented. A 36 year-old male patient admitted to infectious diseases clinic with intense itching, erythematous, raised, streaklike serpiginious eruptionand some redness at bilateral foot especially at the right foot for about one week...
January 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28258982/the-sodium-salt-of-the-enantiomers-of-ricobendazole-preparation-solubility-and-chiroptical-properties
#10
Roberto Cirilli, Paolo Guglielmi, Francesca Romana Formica, Adriano Casulli, Simone Carradori
Albendazole (ABZ) is a sulfanyl-benzimidazole anthelmintic drug used worldwide in the treatment and prevention of parasitic diseases in animals and humans. Following oral administration, ABZ is rapidly oxidized into the pharmacologically active chiral sulfoxide metabolite known as ricobendazole (RBZ). As its achiral precursor, RBZ shows very low intestinal absorption due to its poor solubility in water (0.06mgmL(-1)). To the best of our knowledge, there is no known example in human medicine of a water-soluble salt form of racemic or enantiomerically pure RBZ...
February 20, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28256147/portal-hydatid-with-secondary-cavernomatosis
#11
Mª Belén Rodríguez Sanz, Mª Del Mar Roldán Cuena, Carlos Alberto Blanco Álvarez, Raúl Sánchez Jiménez
The hydatid cyst is a parasitic infection included within the category of zoonoses, in which there exists a direct or indirect relation with animals, particularly with dogs. We report a clinical case of a patient who has undergone surgery of hydatid cyst in the right hepatic lobe. Seven years later the patient presents hydatid cyst in portal vein with secondary cavernomatosis, which is a rare complication. There are few cases described in the literature. The symtomatology presented by hydatid cyst is variable and the diagnosis is made by ultrasonography, TC and/or RNM...
March 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28245883/schistosomiasis-and-soil-transmitted-helminthiasis-in-rwanda-an-update-on-their-epidemiology-and-control
#12
REVIEW
Nadine Rujeni, Domenica Morona, Eugene Ruberanziza, Humphrey D Mazigo
Even though Rwanda lies within a region that has a high prevalence of schistosomiasis and soil-transmitted helminth (STH) infections, epidemiological information regarding these infections in the country remains scarce. The present review attempts to compile the available data on schistosomiasis and STHs, from 1940 to 2014, to provide an insight on the epidemiological profile of these infections. This information will, in turn, support the design and implementation of sustainable control measures. The available records indicate that only Schistosoma mansoni and all the major species of STHs are endemic in Rwanda...
March 1, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28237476/effects-of-albendazole-artesunate-praziquantel-and-miltefosine-on-opisthorchis-viverrini-cercariae-and-mature-metacercariae
#13
Phornphitcha Pechdee, Monticha Chaiyasaeng, Chanisala Sereewong, Jukkrid Chaiyos, Apiporn Suwannatrai, Sutee Wongmaneeprateep, Smarn Tesana
OBJECTIVE: To explore larvicidal effects of anthelmintic drugs on Opisthorchis viverrini (O. viverrini) for alternative approach to interrupting its cycle for developing a field-based control program. METHODS: The larvicidal activities of albendazole (Al), artesunate (Ar), praziquantel (Pzq) and miltefosine (Mf) on O. viverrini cercariae and mature metacercariae were investigated. Lethal concentrations (LC50 and LC95) of these drugs were determined. Mature metacercariae previously exposed to various concentrations of the drugs were administered to hamsters...
February 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28218769/new-world-s-old-disease-cardiac-hydatid-disease-and-surgical-principles
#14
Omer Tanyeli, Yuksel Dereli, Ilker Mercan, Niyazi Gormus, Tahir Yuksek
BACKGROUND: Hydatid cyst is a parasitic disease caused by infection with the Echinococcus granulosus tapeworm larva. It is a major public health problem in endemic regions. Cardiac involvement of the disease is rare. METHODS: Between 1985 and 2015, 12 patients were admitted to our clinic with a possible diagnosis of cardiac hydatid disease. Of these patients, six (50%) were male and six (50%) were female. Mean age of the patients was 42.6 years. RESULTS: The most common location of cardiac hydatid disease was left sided (six patients, 50%)...
February 20, 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/28216368/in-vitro-and-in-vivo-cysticidal-activity-of-extracts-and-isolated-flavanone-from-the-bark-of-prunus-serotina-a-bio-guided-study
#15
Francisca Palomares-Alonso, Irma Susana Rojas-Tomé, Guadalupe Palencia Hernández, María Adelina Jiménez-Arellanes, Martha Lydia Macías-Rubalcava, Angélica González-Maciel, Andrea Ramos-Morales, Rosalba Santiago-Reyes, Nelly Castro, Iliana González-Hernández, Yadira Rufino-González, Helgi Jung-Cook
Currently, neurocysticercosis treatment involves two drugs: albendazole and praziquantel; however, their efficacy is suboptimal and new cysticidal drugs are needed. The present paper reports the cysticidal activity of extracts of the bark from Prunus serotina against Taenia crassiceps cysts and the isolation and identification of the main components of the most active extract. Results showed that all extracts displayed in vitro cysticidal activity (EC50=17.9-88.5μg/mL), being the methanolic the most active and selective...
February 16, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28207792/partnering-for-impact-integrated-transmission-assessment-surveys-for-lymphatic-filariasis-soil-transmitted-helminths-and-malaria-in-haiti
#16
Alaine Kathryn Knipes, Jean Frantz Lemoine, Franck Monestime, Carl R Fayette, Abdel N Direny, Luccene Desir, Valery E Beau de Rochars, Thomas G Streit, Kristen Renneker, Brian K Chu, Michelle A Chang, Kimberly E Mace, Kimberly Y Won, Patrick J Lammie
BACKGROUND: Since 2001, Haiti's National Program for the Elimination of Lymphatic Filariasis (NPELF) has worked to reduce the transmission of lymphatic filariasis (LF) through annual mass drug administration (MDA) with diethylcarbamazine and albendazole. The NPELF reached full national coverage with MDA for LF in 2012, and by 2014, a total of 14 evaluation units (48 communes) had met WHO eligibility criteria to conduct LF transmission assessment surveys (TAS) to determine whether prevalence had been reduced to below a threshold, such that transmission is assumed to be no longer sustainable...
February 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28192198/molecular-cloning-purification-and-characterization-of-brugia-malayi-phosphoglycerate-kinase
#17
Ranjeet Kumar, Pawan Kumar Doharey, Jitendra Kumar Saxena, Sushma Rathaur
Phosphoglycerate kinase (PGK) is a glycolytic enzyme present in many parasites. It has been reported as a candidate molecule for drug and vaccine developments. In the present study, a full-length cDNA encoding the Brugia malayi 3-phosphoglycerate kinase (BmPGK) with an open reading frame of 1.3 kb was isolated and PCR amplified and cloned. The exact size of the BmPGK's ORF is 1377 bps. The BmPGK gene was subcloned into pET-28a (+) expression vector, the expressed enzyme was purified by affinity column and characterized...
February 10, 2017: Protein Expression and Purification
https://www.readbyqxmd.com/read/28179024/impact-of-single-annual-treatment-and-four-monthly-treatment-for-hookworm-and-ascaris-lumbricoides-and-factors-associated-with-residual-infection-among-kenyan-school-children
#18
RANDOMIZED CONTROLLED TRIAL
Stella Kepha, Charles S Mwandawiro, Roy M Anderson, Rachel L Pullan, Fred Nuwaha, Jorge Cano, Sammy M Njenga, Maurice R Odiere, Elizabeth Allen, Simon J Brooker, Birgit Nikolay
BACKGROUND: School-based deworming is widely implemented in various countries to reduce the burden of soil-transmitted helminths (STHs), however, the frequency of drug administration varies in different settings. In this study, we compared the impact of a single annual treatment and 4-monthly treatment over a follow-up among Kenyan school children, and investigated the factors associated with residual infection. METHODS: We performed a secondary analysis of data from a randomized trial investigating whether deworming for STHs alters risk of acquiring malaria...
February 9, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28179008/unexpected-low-soil-transmitted-helminth-prevalence-in-the-butha-buthe-district-in-lesotho-results-from-a-cross-sectional-survey
#19
Wendelin Moser, Niklaus Daniel Labhardt, Molisana Cheleboi, Josephine Muhairwe, Jennifer Keiser
BACKGROUND: Soil-transmitted helminth (STH) infections with Ascaris lumbricoides, hookworm and Trichuris trichiura affect large parts of the world's population. For the implementation of national STH control programs, e.g. preventive chemotherapy (treatment with albendazole and mebendazole), the spatial distribution and prevalence of STH infections must be known. However, for Lesotho only little data were available and the STH distribution remains largely unknown. METHODS: In early 2016, a cross-sectional parasitological STH survey was conducted including six different primary schools in the Butha-Buthe district of Lesotho...
February 8, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28178374/simultaneous-densitometric-determination-of-anthelmintic-drug-albendazole-and-its-metabolite-albendazole-sulfoxide-by-hptlc-in-human-plasma-and-pharmaceutical-formulations
#20
Jui J Pandya, Mallika Sanyal, Pranav S Shrivastav
A new, simple, accurate and precise high-performance thin layer chromatographic method has been developed and validated for simultaneous determination of an anthelmintic drug, albendazole and its active metabolite albendazole sulfoxide. Planar chromatographic separation was performed on aluminium-backed layer of silica gel 60G F254 using a mixture of toluene- acetonitrile-glacial acetic acid (7.0: 2.9: 0.1, v/v/v) as the mobile phase. For quantitation, the separated spots were scanned densitometrically at 225 nm...
February 8, 2017: Biomedical Chromatography: BMC
keyword
keyword
96833
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"