keyword
MENU ▼
Read by QxMD icon Read
search

Albendazole

keyword
https://www.readbyqxmd.com/read/29774301/-mansonella-perstans-onchocerca-volvulus-and-strongyloides-stercoralis-infections-in-rural-populations-in-central-and-southern-togo
#1
Francois Korbmacher, Kossi Komlan, Richard G Gantin, Wiyao P Poutouli, Koffi Padjoudoum, Potchoziou Karabou, Peter T Soboslay, Carsten Köhler
Background: Mansonella perstans , Onchocerca volvulus and Strongyloides stercoralis are widespread helminth parasites in the tropics. Their distribution remains difficult to determine as it may change during national disease control programs and with regional mass drug administration (MDA). Epidemiological surveys are of importance to evaluate the geographical distribution of these helminth parasites and the diseases they may cause, however, up to date epidemiological evaluations on M...
May 2018: Parasite Epidemiology and Control
https://www.readbyqxmd.com/read/29774291/significant-decline-in-lymphatic-filariasis-associated-with-nationwide-scale-up-of-insecticide-treated-nets-in-zambia
#2
M Nsakashalo-Senkwe, E Mwase, E Chizema-Kawesha, V Mukonka, P Songolo, F Masaninga, M P Rebollo, B Thomas, M J Bockarie, H Betts, J R Stothard, L A Kelly-Hope
Lymphatic filariasis (LF) is a mosquito-borne disease, broadly endemic in Zambia, and is targeted for elimination by mass drug administration (MDA) of albendazole and diethylcarbamazine citrate (DEC) to at-risk populations. Anopheline mosquitoes are primary vectors of LF in Africa, and it is possible that the significant scale-up of malaria vector control over the past decade may have also impacted LF transmission, and contributed to a decrease in prevalence in Zambia. We therefore aimed to examine the putative association between decreasing LF prevalence and increasing coverage of insecticide-treated mosquito nets (ITNs) for malaria vector control, by comparing LF mapping data collected between 2003-2005 and 2009-2011 to LF sentinel site prevalence data collected between 2012 and 2014, before any anti-LF MDA was started...
November 2017: Parasite Epidemiology and Control
https://www.readbyqxmd.com/read/29772478/bacillus-thuringiensis-cry5b-protein-as-a-new-pan-hookworm-cure
#3
Yan Hu, Thanh-Thanh Nguyen, Alice C Y Lee, Joseph F Urban, Melanie M Miller, Bin Zhan, David J Koch, Jason B Noon, Ambily Abraham, Ricardo Toshio Fujiwara, Dwight D Bowman, Gary R Ostroff, Raffi V Aroian
Hookworms are intestinal nematode parasites that infect nearly half a billion people and are globally one of the most important contributors to iron-deficiency anemia. These parasites have significant impacts in developing children, pregnant women and working adults. Of all the soil-transmitted helminths or nematodes (STNs), hookworms are by far the most important, with disease burdens conservatively estimated at four million DALYs (Disability-Adjusted Life Years) and with productivity losses of up to US$139 billion annually...
May 4, 2018: International Journal for Parasitology, Drugs and Drug Resistance
https://www.readbyqxmd.com/read/29770671/-prevalence-of-clonorchis-sinensis-infection-and-effect-of-albendazole-treatment-among-residents-in-two-communities-of-zhongshan-city
#4
Zheng Ying-Yan, Xie Ting-Jun, Wang Man, Fang Yue-Yi, Luo Le
OBJECTIVE: To understand the prevalence of Clonorchis sinensis infection among residents in two communities of Zhongshan City, and evaluate the effect of albendazole treatment, so as to offer the evidence for formulating the strategy of clonorchiasis prevention and control. METHODS: The stool specimens were collected from the residents of two comprehensive demonstration areas, and the eggs of C. sinensis were detected by Kato-Katz technique. Those who were tested positive were treated with albendazole (0...
February 22, 2018: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29768412/adverse-events-following-single-dose-treatment-of-lymphatic-filariasis-observations-from-a-review-of-the-literature
#5
Philip J Budge, Carly Herbert, Britt Andersen, Gary J Weil
BACKGROUND: WHO's Global Programme to Eliminate Lymphatic Filariasis (LF) uses mass drug administration (MDA) of anthelmintic medications to interrupt LF transmission in endemic areas. Recently, a single dose combination of ivermectin (IVM), diethylcarbamazine (DEC), and albendazole (ALB) was shown to be markedly more effective than the standard two-drug regimens (DEC or IVM, plus ALB) for achieving long-term clearance of microfilaremia. OBJECTIVE AND METHODS: To provide context for the results of a large-scale, international safety trial of MDA using triple drug therapy, we searched Ovid Medline for studies published from 1985-2017 that reported adverse events (AEs) following treatment of LF with IVM, DEC, ALB, or any combination of these medications...
May 16, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29759885/terfenadone-is-a-strong-inhibitor-of-cyp2j2-present-in-the-human-liver-and-intestinal-microsomes
#6
Eunyoung Lee, Ju-Hyun Kim, Jong Cheol Shon, Zhexue Wu, Hyun Ji Kim, Minsik Gim, Taeho Lee, Kwang-Hyeon Liu
Cytochrome P450 2J2 (CYP2J2) is involved in the metabolism of drugs, including albendazole, astemizole, ebastine, and endogenous substrates. In a previous study, we used recombinant CYP2J2 and determined whether danazol, hydroxyebastine, telmisartan, and terfenadone inhibited CYP2J2 by using four representative CYP2J2 substrates, namely albendazole, astemizole, ebastine, and terfenadine. In this study, we evaluated the inhibitory potential of these four chemicals on human liver and intestinal microsomes, which are commonly used in a reaction phenotyping study...
March 15, 2018: Drug Metabolism and Pharmacokinetics
https://www.readbyqxmd.com/read/29755711/parasitic-hypereosinophilia-in-childhood-a-diagnostic-challenge
#7
Roberto Antonucci, Nadia Vacca, Giulia Boz, Cristian Locci, Rosanna Mannazzu, Claudio Cherchi, Giacomo Lai, Claudio Fozza
Severe hypereosinophilia (HE) in children is rare, and its etiological diagnosis is challenging. We describe a case of a 30-month-old boy, living in a rural area, who was admitted to our Clinic with a 7-day history of fever and severe hypereosinophilia. A comprehensive diagnostic workup could not identify the cause of this condition. On day 6, the rapidly increasing eosinophil count (maximum value of 56,000/mm3 ), the risk of developing hypereosinophilic syndrome, and the patient's history prompted us to undertake an empiric treatment with albendazole...
2018: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/29747967/endless-story-of-a-spinal-column-hydatid-cyst-disease-a-case-report
#8
Gokhan Cavus, Vedat Acik, Emre Bilgin, Yurdal Gezercan, Ali Ihsan Okten
We describe a case of multifocal relapsing hydatid cyst following multilevel thoracic corpectomy and 360° instrumentation surgery. A 41-year-old male patient presented with cord compression and paraplegia due to a multiseptated cystic lesion at T10-11 level. The cyst was excised with a combined anterior and posterior approach and 360° stabilization was performed. The patient received albendazole for 1 year after the surgery. The patient presented with paraparesis 5 years after the surgery. Cystic lesions between C2-T1 and T10-11 were detected on the spinal MRI and the patient was operated with removal of the lesions on both levels and adjuvant local 20% hypertonic saline application...
May 7, 2018: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/29746870/in-vitro-and-in-vivo-efficacies-of-carbazole-aminoalcohols-in-the-treatment-of-alveolar-echinococcosis
#9
Zhisheng Dang, Shuo Xu, Haobing Zhang, Weifeng Gui, Yumin Zhao, Liping Duan, Wei Hu
Benzimidazoles, including albendazole and mebendazole, are the major drugs for clinical chemotherapy of echinococcosis. They mainly exert parasitostatic effects depending on high dosages for long-term. Previous studies have identified carbazole aminoalcohols as novel anti-CE (cystic echinococcosis) agents. However, it is still to be confirmed whether it is effective on alveolar echinococcosis (AE) or not. In the present study, efficacies of novel carbazole aminoalcohols, propylamine, R-propylamine and S-propylamine were evaluated under in vitro and in vivo conditions...
May 7, 2018: Acta Tropica
https://www.readbyqxmd.com/read/29744124/neurological-disorders-caused-by-two-cerebral-alveolar-hydatid-cysts-in-an-old-woman-a-rare-case-report
#10
Hossein Mokhtari, Mohammadamin Sadeghdoust, Farnaz Aligolighasemabadi, Amirhossein Hashemiattar, Vahid Ariabod, Saied Rahighi
Alveolar hydatid disease, caused by Echinococcus multilocularis , is a life-threatening infectious disease which primarily occurs in the liver. Intracranial hydatid disease is a rare presentation with reported incidence of ~1% of all cases. Here we reported a 60-year-old woman, with the past history of hydatid cysts in her liver, who was presented to us with progressive symptoms consist of headaches, diminished vision, cognitive disorders and delusion. She was disoriented in time, space and person. Bilateral mild papilledema and exaggerated reflexes were observed...
August 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29741149/case-report-probable-case-of-spontaneous-encephalopathy-due-to-loiasis-and-dramatic-reduction-of-loa-loa-microfilariaemia-with-prolonged-repeated-courses-of-albendazole
#11
Divine B Arrey-Agbor, Hugues C Nana-Djeunga, Aude E Mogoung-Wafo, Mirabelle Mafo, Christian Danwe, Joseph Kamgno
Loiasis is a vector-borne parasitic disease caused by the filarial nematode Loa loa and transmitted by the tabanid vectors from the genus Chrysops . Loa loa infection is associated with clinical manifestations such as pruritus, migratory transient edema, passage of adult worm in the bulbar conjunctiva, retinal damage, glomerular damage, albuminuria, pleural effusion, hydrocele, and endomyocardial fibrosis. Data reporting the occurrence of spontaneous encephalopathy associated with loiasis are very scanty. Severe adverse events occurring post-ivermectin administered in the framework of the fight against onchocerciasis and/or lymphatic filariasis in loiasis co-endemic areas have been closely associated with very high L...
May 7, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29702653/efficacy-and-safety-of-co-administered-ivermectin-plus-albendazole-for-treating-soil-transmitted-helminths-a-systematic-review-meta-analysis-and-individual-patient-data-analysis
#12
Marta S Palmeirim, Eveline Hürlimann, Stefanie Knopp, Benjamin Speich, Vicente Belizario, Serene A Joseph, Michel Vaillant, Piero Olliaro, Jennifer Keiser
BACKGROUND: The soil-transmitted helminths (STH), Ascaris lumbricoides, Trichuris trichiura and hookworms infect 1.5 billion people worldwide and cause an estimated burden of 3.3 million disability-adjusted life years (DALYs). Current control strategies focus on morbidity reduction through preventive chemotherapy (PC) but the most commonly used recommended drugs (albendazole and mebendazole) are particularly inefficacious against T. trichiura. This, together with the threat of emerging drug resistance, calls for new control strategies, including co-administration with other anthelminthics...
April 27, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29693456/allium-sativum-methanolic-extract-garlic-improve-therapeutic-efficacy-of-albendazole-against-hydatid-cyst-in-vivo-study
#13
K H Haji Mohammadi, M Heidarpour, H Borji
After gas chromatography and mass spectrometry of prepared methanolic extract of Allium sativum, 40 laboratory BALB/c mice were infected intraperitoneally by injection of 1,500 viable protoscoleces. Five months after infection, the infected mice were allocated into four treatment groups, including 1- Albendazole (100 mg/kg); 2- Allium sativum methanolic extract (10 mL/L); 3- A. sativum methanolic extract (10 mL/L) + Albendazole (50 mg /kg); and 4- untreated control group. After 30 days of daily treatment, total number and weight of cysts and size of the largest cyst as well as blood serum bilirubin and liver enzymes were compared between the mice of different groups...
April 25, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29683544/high-folate-levels-are-not-associated-with-increased-malaria-risk-but-with-reduced-anemia-rates-in-the-context-of-high-dosed-folate-supplements-and-intermittent-preventive-treatment-against-malaria-in-pregnancy-with-sulphadoxine-pirymethamine-in-benin
#14
Violeta Moya-Alvarez, Smaila Ouédraogo, Manfred Accrombessi, Michel Cot
OBJECTIVES: To investigate if high-dosed folate supplements might diminish the efficacy of malaria intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) in a cohort of pregnant women in Benin, where malaria is holoendemic. METHODS: We followed 318 women during the entire pregnancy and analyzed hematological and P.falciparum indicators in the context of an intermittent preventive treatment trial in Benin. During the follow-up women received two-dose IPTp (1500/75 mg of SP per dose) at the maternity clinic, and 600 mg of albendazole, 200 mg ferrous sulfate and 5 mg folic acid per day for home treatment...
April 23, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29682390/hydatid-cyst-of-the-adrenal-gland-is-radical-surgery-necessary-for-recurrent-hydatid-disease
#15
Sami Akbulut, Mehmet Yilmaz
Hydatid cyst disease caused by E. granulosus is a zoonotic disease that may involve many body tissues and organs, mainly liver. Adrenal glands are rarely involved even in regions where hydatid cyst disease is endemic. A limited number of studies have been reported on adrenal gland involvement by hydatid cyst disease. Herein, we aimed to report a recurrent case of adrenal hydatid cyst that was misdiagnosed as a hepatic hydatid cyst. A 16-year-old boy with a history of partial cyst excision and evacuation for perforated adrenal hydatid cyst disease three years ago presented to our outpatient clinic with nonspecific abdominal pain...
2018: Case Reports in Surgery
https://www.readbyqxmd.com/read/29677189/progress-in-the-pharmacological-treatment-of-human-cystic-and-alveolar-echinococcosis-compounds-and-therapeutic-targets
#16
Mar Siles-Lucas, Adriano Casulli, Roberto Cirilli, David Carmena
Human cystic and alveolar echinococcosis are helmintic zoonotic diseases caused by infections with the larval stages of the cestode parasites Echinococcus granulosus and E. multilocularis, respectively. Both diseases are progressive and chronic, and often fatal if left unattended for E. multilocularis. As a treatment approach, chemotherapy against these orphan and neglected diseases has been available for more than 40 years. However, drug options were limited to the benzimidazoles albendazole and mebendazole, the only chemical compounds currently licensed for treatment in humans...
April 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29673735/efficacy-and-tolerability-of-triple-drug-therapy-with-albendazole-pyrantel-pamoate-and-oxantel-pamoate-compared-with-albendazole-plus-oxantel-pamoate-pyrantel-pamoate-plus-oxantel-pamoate-and-mebendazole-plus-pyrantel-pamoate-and-oxantel-pamoate-against-hookworm
#17
Wendelin Moser, Somphou Sayasone, Syda Xayavong, Bangon Bounheuang, Maxim Puchkov, Jörg Huwyler, Jan Hattendorf, Jennifer Keiser
BACKGROUND: Albendazole and mebendazole are commonly used to control hookworm, but have shortcomings in their efficacy profiles. We assessed whether triple drug therapy (TDT) with albendazole, pyrantel pamoate, and oxantel pamoate was more effective than the co-administration of two drugs for the treatment of hookworm infections. METHODS: A randomised, single-blind trial was done from Sept 27 until Nov 17, 2017, in Laos. Children (6-15 years) from six schools were invited to participate...
April 16, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29672249/urinary-tract-infection-by-strongyloides-stercoralis-a-case-report
#18
Nilo Manoel Pereira Vieira Barreto, Joelma Nascimento de Souza, Weslei Almeida Costa Araujo, Nadia Andrade Khouri, Ernesto Pereira de Oliveira, Márcia Cristina Aquino Teixeira, Neci Matos Soares
The objective of this study was to report a case of a hydronephrotic patient with Strongyloides stercoralis infection, with discharge of rhabditoid larva exclusively in urine. In 2013, a 72-yr-old, male patient, hypertensive, obese and diagnosed with hydronephrosis secondary to renal calculi, reported lumbar pain, polyuria, polaciuria and dysuria, as well as frequent urinary tract infections. The microscopic analysis of urine sediment showed the presence of S. stercoralis rabditoid larva. However, parasitological examinations by Baermann-Moraes, agar plate culture and spontaneous sedimentation, performed with 3 fecal samples on alternate days had negative results...
April 19, 2018: Journal of Parasitology
https://www.readbyqxmd.com/read/29663166/anthelmintic-efficacy-of-glycolipid-biosurfactant-produced-by-pseudomonas-plecoglossicida-an-insight-from-mutant-and-transgenic-forms-of-caenorhabditis-elegans
#19
Sabarinathan Devaraj, Mohankumar Amirthalingam, Poorna Chandrika Sabapathy, Shanmugam Govindan, Sundararaj Palanisamy, Preethi Kathirvel
The current research focuses on the production and characterization of glycolipid biosurfactant (GB) from Pseudomonas plecoglossicida and its anthelmintic activity against Caenorhabditis elegans. The GB was purified and characterized by Fourier Transform Infrared Spectroscopy (FTIR) and Gas Chromatography and Mass Spectrometry (GC-MS) analysis. Anthelmintic activity of GB was studied at six different pharmacological doses from 10 to 320 µg/mL on C. elegans. Exposure of different developmental stages (L1, L2, L3, L4 and adult) of C...
April 16, 2018: Biodegradation
https://www.readbyqxmd.com/read/29661454/successful-treatment-of-strongyloides-stercoralis-hyperinfection-in-a-kidney-transplant-recipient-case-report
#20
J Rego Silva, R A Macau, A Mateus, P Cruz, M J Aleixo, M Brito, A Alcobia, C Oliveira, A Ramos
Strongyloides stercoralis (SS) can cause hyperinfection and disseminated infection in immunosuppressed individuals, with risk of mortality. We report the case of a cadaveric kidney transplant recipient who developed gastrointestinal symptoms and eosinophilia, approximately 3 months after transplantation. Stool examination and esophagogastroduodenoscopy with biopsies were positive for SS larvae. The patient was started on oral ivermectin and immunosuppression was reduced, but still the clinical picture got worse with metabolic ileus and respiratory symptoms, with the need for administration of subcutaneous ivermectin and combined therapy with albendazol...
April 2018: Transplantation Proceedings
keyword
keyword
96833
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"