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JOURNAL ARTICLE
Zainali S Chunawala, Melissa C Caughey, Deepak L Bhatt, Michael Hendrickson, Sameer Arora, Sripal Bangalore, John P Erwin, Justin P Levisay, Jonathan R Rosenberg, Mark J Ricciardi, Ron Blankstein, Kunihiro Matsushita, Sidney Smith, Arman Qamar
Background Prevention strategies targeting standard modifiable cardiovascular risk factors (SMuRFs; diabetes, hypertension, smoking, hypercholesterolemia) are critical to improving cardiovascular disease outcomes. However, acute myocardial infarction (AMI) among individuals who lack 1 or more SMuRFs is not uncommon. Moreover, the clinical characteristics and prognosis of SMuRFless individuals are not well characterized. Methods and Results We analyzed AMI hospitalizations from 2000 to 2014 captured by the ARIC (Atherosclerosis Risk in Community) study community surveillance...
June 29, 2023: Journal of the American Heart Association
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JOURNAL ARTICLE
Peta Lonski, Michael MacManus, Belinda A Campbell, Greg Wheeler, Elena Ungureanu, Tomas Kron
INTRODUCTION: Total body irradiation (TBI) practices vary considerably amongst centres, and the risk of treatment related toxicities remains unclear. We report lung doses for 142 TBI patients who underwent either standing TBI with lung shield blocks or lying TBI without blocks. METHODS: Lung doses were calculated for 142 TBI patients treated between June 2016 and June 2021. Patients were planned using Eclipse (Varian Medical Systems) using AAA_15.6.06 for photon dose calculations and EMC_15...
June 21, 2023: Journal of Medical Imaging and Radiation Oncology
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JOURNAL ARTICLE
Timothy D Keiper, Kelly Kisling, Patricia Hua, Ryan P Manger
PURPOSE: To compare the superficial dose when using brass mesh bolus (BMB), no bolus, or 3 mm tissue-equivalent bolus with a pseudo-flash volumetric modulated arc therapy (VMAT) breast treatment planning technique. METHODS: Two different beam arrangements for right-sided irradiation and one beam arrangement for bilateral irradiation were planned on an inhomogeneous thorax phantom in accordance with our clinical practice for VMAT postmastectomy radiotherapy (PMRT)...
June 7, 2023: Journal of Applied Clinical Medical Physics
#24
JOURNAL ARTICLE
Heng-Liang Liu, Zi-Xuan Jin, Ke-Lei Su, Peng-Qian Wang, Xing-Jiang Xiong
Chaihu Jia Longgu Muli Decoction was firstly recorded in Treatise on Cold Damage(ZHANG Zhong-jing, Eastern Han dynasty). According to this medical classic, it is originally used in the treatment of the Shaoyang and Yangming syndrome. Based on the modern pathophysiological mechanism, this study interpreted the classic provisions of Chaihu Jia Longgu Muli Decoction. Original records of "chest fullness" "annoyance" "shock" "difficult urination" "delirium" "heavy body and failing to turn over" all have profound pathophysiological basis, involving disorders in cardiovascular, respiratory, nervous, and mental systems...
May 2023: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
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JOURNAL ARTICLE
Steindór Ellertsson, Hlynur D Hlynsson, Hrafn Loftsson, Emil L Sigur Sson
PURPOSE: Respiratory symptoms are the most common presenting complaint in primary care. Often these symptoms are self resolving, but they can indicate a severe illness. With increasing physician workload and health care costs, triaging patients before in-person consultations would be helpful, possibly offering low-risk patients other means of communication. The objective of this study was to train a machine learning model to triage patients with respiratory symptoms before visiting a primary care clinic and examine patient outcomes in the context of the triage...
2023: Annals of Family Medicine
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JOURNAL ARTICLE
Jin An, Ji-Hyang Lee, Youngsang Yoo, Hyouk-Soo Kwon, Jae-Seung Lee, Sei Won Lee, Tae-Bum Kim, Yeon-Mok Oh, You Sook Cho, Sang-Do Lee, Woo-Jung Song
BACKGROUND: The role of chest computed tomography (CT) scan is controversial in the management of chronic cough patients with normal chest X-rays. We investigated the utilization pattern and diagnostic outcomes of chest CT scans using institutional routinely collected data (RCD) in South Korea. METHODS: This is a retrospective analysis of adults with chronic cough (>8 weeks in duration) identified from routinely collected electronic health records (EHRs). Structured data were retrieved, including demographics, medical history, symptoms, and diagnostic test results (including chest X-rays and CT scans)...
April 28, 2023: Journal of Thoracic Disease
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JOURNAL ARTICLE
Tarso Augusto Duenhas Accorsi, Renato Paladino Nemoto, Jairo Tavares Nunes, Antônio Fernando Barros de Azevedo Filho, Flavio Tocci Moreira, Karen Francine Kohler, Karine de Amicis Lima, Bruna Dayanne Reges Amaral, Renata Albaladejo Morbeck, Carlos Henrique Sartorato Pedrotti
BACKGROUND: Cardiovascular diseases are the leading cause of adult mortality. Geographically remote and low-income Brazilian regions lack specialized consultations. The telemedicine management of this population by cardiologists is not fully known. OBJECTIVES: To analyze cardiology teleconsultation in the Brazilian region with the highest number of isolated cities. METHODS: From February 2020 to October 2021, patients from the North Region of Brazil evaluated by local general practitioners were referred for cardiological evaluation by telemedicine...
April 2023: Arquivos Brasileiros de Cardiologia
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JOURNAL ARTICLE
Reena Phurailatpam, Muktar Kumar Sah, Tabassum Wadasadawala, Asfiya Khan, Jithin Palottukandy, Umesh Gayake, Jeevanshu Jain, Rajiv Sarin, Rima Pathak, Revathy Krishnamurthy, Kishore Joshi, Jamema Swamidas
INTRODUCTION: To validate and evaluate the performance of knowledge-based treatment planning for Volumetric Modulated Arc Radiotherapy for post-mastectomy loco-regional radiotherapy. MATERIAL AND METHODS: Two knowledge-based planning (KBP) models for different dose prescriptions were built using the Eclipse RapidPlanTM v 16.1 (Varian Medical Systems, Palo Alto, USA) utilising the plans of previously treated patients with left-sided breast cancer who had undergone irradiation of the left chest wall, internal mammary nodal (IMN) region and supra-clavicular fossa (SCF)...
2023: Frontiers in Oncology
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JOURNAL ARTICLE
Pokhraj P Suthar, Miral Jhaveri, Mustafa Mafraji
A 44-year-old previously healthy man with a 9-month history of progressive cognitive decline, depression, urinary incontinence, and inability to perform tasks of daily living presented to the emergency department with worsening cognitive and neuropsychiatric symptoms. He had become more distressed, and his family noticed him departing the house without closing doors, leaving water faucets running, and sending his children to school on Sundays. History taken from the patient's wife revealed that his brother had passed away in his late 30s after a slowly progressing functional and cognitive decline over the course of 5 years...
May 2023: Radiology
#30
JOURNAL ARTICLE
Pei-An Liao, Sheng-Wei Pan, Chun-Yu Chen, Chung-Yeh Deng, Yaa-Hui Dong
BACKGROUND: The clinical guideline recommends use of long-acting β2 agonists/long-acting muscarinic antagonists (LABA/LAMA) or long-acting β2 agonists/inhaled corticosteroids (LABA/ICS) combination therapies for patients with severe chronic obstructive pulmonary disease (COPD). The fixed-dose combination (FDC) inhalers of LABA/LAMA and LABA/ICS were reimbursed in Taiwan in 2015 and in 2002, respectively. This study aimed to examine prescription patterns of new use of either FDC therapy in real-world practice...
2023: International Journal of Chronic Obstructive Pulmonary Disease
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JOURNAL ARTICLE
Daniel Fernandez-Guzman, Brenda Caira-Chuquineyra, Fiorella Baca-Rondan, Maria Cristina Yucra-Sosa, Fabricio Ccami-Bernal, David R Soriano-Moreno, Wendy Nieto-Gutierrez, Vicente A Benites-Zapata
OBJECTIVE: To evaluate the association between self-rated evidence-based medicine (EBM) competencies and the prescription of drugs without scientific evidence against mild COVID-19 (present with any of the signs and symptoms of COVID-19 but who do not have shortness of breath, dyspnea, or abnormal chest imaging) among recently graduated physicians in Peru. METHODS: We conducted an analytical cross-sectional study where we evaluated a non-probability sample of recently graduated physicians during June and July 2021 (end of second wave of COVID-19 in Peru)...
April 2023: Heliyon
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JOURNAL ARTICLE
Carlotta Biagi, Ludovica Betti, Elisa Manieri, Arianna Dondi, Luca Pierantoni, Ramsiya Ramanathan, Daniele Zama, Monia Gennari, Marcello Lanari
Bronchiolitis is the main cause of hospitalization in infants. Diagnosis is clinical, and treatment is based on hydration and oxygen therapy. Nevertheless, unnecessary diagnostic tests and pharmacological treatments are still very common. This retrospective study aimed to evaluate whether the setting of bronchiolitis care influences diagnostic and therapeutic choices. The management of 3201 infants, referred to our Italian Tertiary Care Center for bronchiolitis between 2010 and 2020, was analyzed by comparing children discharged from the pediatric emergency department (PEDd group) undergoing short-stay observation (SSO group) and hospitalization...
February 24, 2023: Life
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JOURNAL ARTICLE
Sara Ares-Blanco, Marina Guisado-Clavero, Lourdes Ramos Del Rio, Ileana Gefaell Larrondo, Louise Fitzgerald, Limor Adler, Radost Assenova, Maria Bakola, Sabine Bayen, Elena Brutskaya-Stempkovskaya, Iliana-Carmen Busneag, Philippe-Richard Domeyer, Dragan Gjorgjievski, Kathryn Hoffmann, Оксана Ільков, Vasilis Trifon Karathanos, Aleksandar Kirkovski, Snežana Knežević, Büsra Çimen Korkmaz, Bruno Heleno, Katarzyna Nessler, Liubovė Murauskienė, Ana Luisa Neves, Naldy Parodi López, Ábel Perjés, Davorina Petek, Ferdinando Petrazzuoli, Goranka Petricek, Bohumil Seifert, Alice Serafini, Theresa Sentker, Paula Tiili, Péter Torzsa, Bert Vaes, Gijs van Pottebergh, Shlomo Vinker, María Pilar Astier-Peña, Raquel Gómez-Bravo, Heidrun Lingner
BACKGROUND: Most COVID-19 patients were treated in primary health care (PHC) in Europe. OBJECTIVES: To demonstrate the scope of PHC workflow during the COVID-19 pandemic emphasising similarities and differences of patient's clinical pathways in Europe. METHODS: Descriptive, cross-sectional study with data acquired through a semi-structured questionnaire in PHC in 30 European countries, created ad hoc and agreed upon among all researchers who participated in the study...
December 2023: European Journal of General Practice
#34
JOURNAL ARTICLE
Yuqin Zeng, Martijn A Spruit, Qichen Deng, Frits M E Franssen, Ping Chen
BACKGROUND: Sex differences in symptoms exist in patients with COPD. Our aim is to measure the differences between men and women with COPD, focusing on risk factors, symptoms, quality of life and drug prescriptions. METHODS: In this cross-sectional observational study, patients with COPD were collected in China; demographic characteristics, smoking history, occupational exposure, biomass exposure, lung function, dyspnea, quality of life, and prescriptions for inhaled medications were collected...
January 21, 2023: Toxics
#35
JOURNAL ARTICLE
José Knüsli, Loïc Lhopitallier, Andreas Kronenberg, Jean-Yves Meuwly, Onya Opota, Marc-Antoine Perrenoud, Marie-Anne Page, Kevin C Kain, Aline Mamin, Valérie D'Acremont, Nicolas Senn, Yolanda Mueller, Isabella Locatelli, Noémie Boillat-Blanco
BACKGROUND: Lower respiratory tract infections (LRTIs) in primary care are a promising target for antibiotic stewardship. A clinical trial in Switzerland showed a large decrease in antibiotic prescriptions with procalcitonin guidance (cut-off < 0.25 µg/L) compared with usual care. However, one-third of patients with low procalcitonin at baseline received antibiotics by day 28. AIM: To explore the factors associated with the overruling of initial procalcitonin guidance...
February 12, 2023: Antibiotics
#36
JOURNAL ARTICLE
Yi-Ran Zhao, Qian Li, Min Wang, Ying Gao, Zhen-Yuan Chen, Jing Li
Based on data mining technology, the rules of acupoint selection of acupuncture-moxibustion for scrofula in ancient times were analyzed. The relevant articles of acupuncture and moxibustion for scrofula were searched in the Chinese Medical Code , and the original article, acupoint name, acupoint characteristic, and acupoint meridian tropism, etc. were screened and extracted. The Microsoft Excel 2019 was used to establish a acupoint prescription database, and the frequency of acupoints as well as their meridian tropism and characteristics were analyzed...
February 12, 2023: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
#37
JOURNAL ARTICLE
Bhavika Kaul, Joyce S Lee, Laura A Petersen, Charles McCulloch, Ivan O Rosas, Venkata D Bandi, Ning Zhang, Alison M DeDent, Harold R Collard, Mary A Whooley
BACKGROUND: Two antifibrotic medications, pirfenidone and nintedanib, are approved for the treatment of idiopathic pulmonary fibrosis (IPF). Little is known about their real-world adoption. RESEARCH QUESTION: What are the real-world antifibrotic utilization rates and factors associated with uptake among a national cohort of veterans with IPF? STUDY DESIGN AND METHODS: This study identified veterans with IPF who received care either provided by the Veterans Affairs (VA) Healthcare System or non-VA care paid for by the VA...
August 2023: Chest
#38
JOURNAL ARTICLE
Ali Amanati, Mahdi Shahriari, Mohammad Reza Bordbar, Seyyed Bozorgmehr Hedayati, Mazyar Ziyaeyan, Marzieh Jamalidoust, Mehdi Kalani, Nahid Heydari Marandi
BACKGROUND: Like other viral infections, severe acute respiratory syndrome coronavirus-2 infection could affect different human body systems, including host immune responses. Three years after its pandemic, we learn more about this novel coronavirus. As we expected, different co-infections with various organisms, such as viruses, bacteria, and even fungi, have been reported. However, concurrent infection with two severe acute respiratory syndrome coronavirus-2 strains and cytomegalovirus is extremely unusual...
February 10, 2023: Journal of Medical Case Reports
#39
JOURNAL ARTICLE
Yeliz Akturk, Serra Ozbal Gunes, Esra Soyer Guldogan, Irfan Sencan, Baki Hekimoğlu
OBJECTIVES: It is known that COVID-19 has multisystemic effects. However, its early effects on muscle tissue have not been clearly elucidated. The aim of this study is to investigate early changes in the pectoral muscle in patients with COVID-19 infection. MATERIALS AND METHODS: The pectoral muscle areas (PMA) and pectoral muscle index (PMI) of 139 patients diagnosed with COVID-19 were measured from chest CTs taken at the time of the first diagnosis and within 6 months after the diagnosis...
February 1, 2023: Radiología
#40
JOURNAL ARTICLE
Juana María Plasencia-Martínez, Rafael Pérez-Costa, Mónica Ballesta-Ruiz, José María García-Santos
OBJECTIVE: Rapid progression of COVID-19 pneumonia may put patients at risk of requiring ventilatory support, such as non-invasive mechanical ventilation or endotracheal intubation. Implementing tools that detect COVID-19 pneumonia can improve the patient's healthcare. We aim to evaluate the efficacy and efficiency of the artificial intelligence (AI) tool GE Healthcare's Thoracic Care Suite (featuring Lunit INSIGHT CXR, TCS) to predict the ventilatory support need based on pneumonic progression of COVID-19 on consecutive chest X-rays...
January 31, 2023: Radiología
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